Anchoring guide wire for nerve intervention

Abstract

The invention provides a nerve intervention anchoring guide wire, and relates to the technical field of medical instruments, the nerve intervention anchoring guide wire comprises a main guide wire, the main guide wire comprises a core wire, the far end of the core wire is sequentially connected with a first supporting ball and a second supporting ball in the axial direction, and when the first supporting ball and the second supporting ball are in an expansion state, the expansion size can be adjusted. The first supporting ball and the second supporting ball are controlled through a pull wire, and the pull wire penetrates through the core wire and extends to the near end of the core wire. The radial supporting force of the anchoring guide wire in a blood vessel is improved by increasing the number of the supporting balls, so that a more stable fixing effect is provided, the supporting force of the first supporting ball and the supporting force of the second supporting ball can be adjusted by arranging the first pull wire and the second pull wire, secondary expansion of the first supporting ball and the second supporting ball can be achieved, and therefore the problem of insufficient supporting force is solved. The first supporting ball and the second supporting ball can be obtained by weaving weaving wires, and filter membranes are laid on the surfaces of the first supporting ball and the second supporting ball, so that thrombus in blood flow can be filtered while the supporting effect is achieved.

Description

Technical Field

[0001] The invention belongs to the technical field of medical devices, and in particular relates to a neural intervention anchoring guidewire. Background Art

[0002] Stroke, commonly known as stroke, is divided into two types: ischemic stroke and hemorrhagic stroke. It is a disease caused by various reasons that damage cerebral blood vessels and cause focal or overall brain tissue damage. Common symptoms include sudden numbness or weakness, language or comprehension problems, vision problems, headache, dizziness, etc. Ischemic stroke accounts for the vast majority of strokes and can usually be treated with neurointerventional surgery.

[0003] Neurointerventional surgery uses intravascular catheter operation technology with the support of angiography system to diagnose and treat lesions involving the human neurovascular system through specific methods such as selective angiography, embolization, dilatation, mechanical removal, and drug delivery. Specifically, neurointerventional surgery first establishes a pathway through the guidance of a guidewire, and then delivers the treatment device to the lesion through a catheter and releases it to achieve the treatment purpose. In neurointerventional treatment surgery, the operator often needs to exchange multiple interventional devices. However, in the process of exchanging interventional devices, due to the large interaction force between the guidewire and the device, it is very likely to cause the guidewire to shift, or even cause the guidewire to move out of the lesion, resulting in prolonged operation time and even affecting the treatment effect.

[0004] An anchoring guidewire is a guidewire whose distal end can be fixed on the blood vessel wall. A support ball is provided at the distal end. When the support ball expands, it contacts the blood vessel wall and applies pressure to the blood vessel wall, thereby fixing the anchoring guidewire to the inner wall of the blood vessel. This can prevent the guidewire from being displaced when a catheter or other instrument is subsequently pushed along the guidewire.

[0005] However, the existing anchoring guidewires still have the following shortcomings, such as: the guidewire tip is too long, which affects the positioning of the support ball; the radial support force of the support ball is insufficient, and displacement may occur during the operation; there is a risk of the wire untwisting and falling off the guidewire.

[0006] Therefore, it is necessary to provide an improved technical solution to address the above-mentioned deficiencies in the prior art. Summary of the invention

[0007] The purpose of the present invention is to provide a neurointervention anchoring guidewire with good supporting force and positioning ability to solve the problems existing in the existing anchoring guidewires.

[0008] In order to achieve the above object, the present invention provides the following technical solutions:

[0009] A neurointervention anchoring guidewire includes a main guidewire, wherein the main guidewire includes a core wire, wherein the distal end of the core wire is axially connected to a first support ball and a second support ball in sequence, and when the first support ball and the second support ball are in an expanded state, their expanded sizes are adjustable.

[0010] Preferably, the first support ball and the second support ball are controlled by a pull wire, and the pull wire passes through the core wire and extends to the proximal end of the core wire.

[0011] Preferably, the pull wire comprises a first pull wire and a second pull wire, when the first pull wire is pulled, the first support ball gradually expands, and when the second pull wire is pulled, the second support ball gradually expands.

[0012] Preferably, the first pull wire is connected to the distal end of the first support ball, and the second pull wire is connected to the distal end of the second support ball.

[0013] Preferably, the first support ball and / or the second support ball are woven from a plurality of elastic threads.

[0014] Preferably, a winding wire is provided on the outer surface of the core wire, the winding wire is spiral and covers at least the distal end of the core wire, and the proximal end of the winding wire extends to the proximal end of the second supporting ball.

[0015] Preferably, heat shrink tubes are provided at both ends of the first support ball and / or the second support ball, and the heat shrink tubes cover the connection between the first support ball and / or the second support ball and the core wire.

[0016] Preferably, the distal end of the core wire is located inside the distal end of the first support ball.

[0017] Preferably, a filter membrane is disposed on the surface of the first support ball and / or the second support ball.

[0018] Preferably, a support rod is provided on the inner side of the core wire, and the support rod is connected to the proximal end of the second support ball.

[0019] Beneficial effects:

[0020] (1) The neurointervention anchoring guidewire provided by the present invention is provided with two support balls, which increases the radial support force of the anchoring guidewire in the blood vessel and can solve the problem of insufficient anchoring force;

[0021] (2) The distal end of the core wire is located inside the distal end of the first support ball, thereby preventing the excessively long distal end of the guide wire from affecting the placement of the first support ball;

[0022] (3) The first support ball and the second support ball are controlled by a pull wire inside the core wire, and the expansion degree of the first support ball and the second support ball can be adjusted at the proximal end of the core wire, thereby ensuring that the supporting force of the first support ball and the second support ball is moderate;

[0023] (4) The first support ball and the second support ball can be woven from a plurality of elastic threads, so that the first support ball and the second support ball can act as a filter to filter the blood flow, thereby preventing the thrombus fragments generated during the operation from escaping to the distal end of the blood vessel. On this basis, a filter membrane can be further laid on the surface of the first support ball and the second support ball to improve the filtering effect;

[0024] (5) The wire wrapping outside the core wire is fixed to the core wire through a heat shrink tube, which can effectively prevent the wire wrapping from untwisting and falling off. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] The drawings constituting a part of the present application are used to provide a further understanding of the present invention. The exemplary embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation of the present invention. Among them:

[0026] Figure 1 This is a front view of a neurointervention anchoring guidewire provided in Example 1 of the present invention.

[0027] Figure 2 This is a schematic structural diagram of a neurointervention anchoring guidewire provided in Example 1 of the present invention.

[0028] Figure 3 This is a front view of a neurointervention anchoring guidewire provided in Example 2 of the present invention.

[0029] Figure 4 This is a front view of a neurointervention anchoring guidewire provided in Example 4 of the present invention.

[0030] Figure 5 This is a front view of a neurointervention anchoring guidewire provided in Example 5 of the present invention.

[0031] Figure 6 It is a schematic diagram of arranging a winding wire outside the core wire in an embodiment of the present invention.

[0032] In the figure: 100, core wire; 101, winding wire; 201, first support ball; 202, second support ball; 301, first pull wire; 302, second pull wire; 400, heat shrink tube; 500, filter membrane; 600, support rod. DETAILED DESCRIPTION

[0033] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention belong to the scope of protection of the present invention.

[0034] In the description of the present invention, it should be understood that descriptions involving orientations, such as up, down, front, back, left, right, etc., and orientations or positional relationships indicated are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0035] In the description of the present invention, "several" means one or more, "more" means more than two, "greater than", "less than", "exceed" etc. are understood as not including the number itself, and "above", "below", "within" etc. are understood as including the number itself. If there is a description of "first" or "second", it is only used for the purpose of distinguishing the technical features, and cannot be understood as indicating or implying the relative importance or implicitly indicating the number of the indicated technical features or implicitly indicating the order of the indicated technical features.

[0036] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, the features defined as "first" and "second" may explicitly or implicitly include one or more features.

[0037] In the present invention, "proximal end" refers to the end close to the operator, and "distal end" refers to the end far from the operator. Unless otherwise specified, the left side in the drawings is the "proximal end" and the right side is the "distal end".

[0038] In the description of the present invention, it should be noted that, unless otherwise clearly stipulated and limited, the term "connection" should be understood in a broad sense. For example, it can be a fixed connection or a movable connection, a detachable connection or a non-detachable connection, or an integral connection; it can be a mechanical connection, an electrical connection, or mutual communication; it can be a direct connection, or an indirect connection through an intermediate medium, and it can be internal connection between two elements, indirect connection, or an interactive relationship between two elements.

[0039] The present invention will be described in detail below in conjunction with embodiments. It should be noted that the embodiments and features in the embodiments of the present invention can be combined with each other without conflict.

[0040] In view of the problems of insufficient radial supporting force in current anchoring guidewires, the present invention provides a neurointervention anchoring guidewire, comprising a main guidewire, the main guide wire comprising a core wire 100, the distal end of the core wire 100 being axially connected to a first support ball 201 and a second support ball 202 in sequence, and when the first support ball 201 and the second support ball 202 are in an expanded state, their expanded sizes can be adjusted.

[0041] In view of the different anchoring positions of the first support ball 201 and the second support ball 202 in the blood vessel, the inner diameters of the blood vessels corresponding to their anchoring positions are also different, and their expansion sizes are adjustable, which can well solve the adaptation problem between the support balls and the inner diameters of the blood vessels. By setting two support balls, the radial support force of the anchoring guide wire in the blood vessel is increased, which can solve the problem of insufficient anchoring force. Furthermore, the first support ball 201 and the second support ball 202 are controlled by a pull wire, which passes through the core wire 100 and extends to the proximal end of the core wire 100. The expansion degree of the first support ball 201 and the second support ball 202 can be adjusted by operating the pull wire at the proximal end.

[0042] Specifically, the pull wire includes a first pull wire 301 and a second pull wire 302. The first pull wire 301 is connected to the distal end of the first support ball 201. When the first pull wire 301 is pulled, the first support ball 201 gradually expands. The second pull wire 302 is connected to the distal end of the second support ball 202. When the second pull wire 302 is pulled, the second support ball 202 gradually expands.

[0043] In a preferred embodiment of the present invention, the first support ball 201 and / or the second support ball 202 are woven from a plurality of elastic threads, and their shapes are as shown in the figure, so that the first support ball 201 and the second support ball 202 can act as a filter to filter the blood flow, thereby preventing thrombus fragments generated during the operation from escaping to the distal end of the blood vessel.

[0044] Furthermore, a filter membrane 500 is applied on the surface of the first support ball 201 and / or the second support ball 202 to enhance the filtering effect on micro thrombi.

[0045] In a preferred embodiment of the present invention, Figure 6 As shown, a winding wire 101 is provided on the outer surface of the core wire 100 . The winding wire 101 is spiral and covers at least the distal end of the core wire 100 . The proximal end of the winding wire 101 extends to the proximal end of the second supporting ball 202 .

[0046] In a preferred embodiment of the present invention, heat shrink tubes 400 are provided at both ends of the first support ball 201 and / or the second support ball 202. The heat shrink tubes 400 cover the connection between the first support ball 201 and / or the second support ball 202 and the core wire 100. On the one hand, they can be used to further fix the first support ball 201 and / or the second support ball 202 to make it difficult for them to fall off the core wire 100. On the other hand, they can be used to fix the winding wire 101 on the outer surface of the core wire 100 to prevent the winding wire 101 from untwisting and falling off. The heat shrink tube 400 can be made of PTFE material.

[0047] In addition, in some embodiments, the first support ball 201 and the second support ball 202 are integrated with the core wire 100 , which can avoid the problem of the first support ball 201 and the second support ball 202 falling off.

[0048] In a preferred embodiment of the present invention, the distal end of the core wire 100 is located inside the distal end of the first support ball 201 to prevent the distal end of the core wire 100 from being too long and affecting the first support ball 201 from being in place.

[0049] In a preferred embodiment of the present invention, a support rod 600 is provided on the inner side of the core wire 100, and the support rod 600 is connected to the proximal end of the second support ball 202. The first support ball 201 and the second support ball 202 can be conveniently adjusted by means of the support rod 600. Specifically, the support rod 600 can be held at the proximal end of the core wire 100, and then the first pull wire 301 can be pulled to expand the first support ball 201 for a second time. At this time, the proximal end of the first pull wire 301 can be fixed to the core wire 100 with a fixing clip, so that the first support ball 201 can maintain the supporting force; when the second support ball 202 needs to be adjusted, the core wire 100 acts as a support, and the second support ball 202 can be expanded for a second time by pulling the second pull wire 302.

[0050] The following is a detailed description of a neural intervention anchoring guidewire of the present invention through specific embodiments.

[0051] Example 1

[0052] This embodiment provides a neural intervention anchoring guidewire, such as Figure 1 , 2 As shown, it includes a core wire 100, the distal end of the core wire 100 is connected to the first support ball 201 and the second support ball 202 in sequence along the axial direction, and the first support ball 201 is located at the distal end of the second support ball 202, the distal end of the core wire 100 is flush with the distal end of the first support ball 201, and the core wire 100 adopts a hollow structure, and its proximal end and distal end are connected to form an inner cavity, and the first pull wire 301 and the second pull wire 302 are arranged in the inner cavity, wherein the first pull wire 301 is connected to the distal end of the first support ball 201, and the second pull wire 302 is connected to the distal end of the second support ball 202, and the first pull wire 301 and the second pull wire 302 do not interfere with each other.

[0053] In this embodiment, when the first pull wire 301 or the second pull wire 302 is pulled toward the proximal direction, the distal end of the first support ball 201 or the second support ball 202 can be moved closer to the proximal direction, thereby squeezing the first support ball 201 or the second support ball 202, causing it to expand and gradually increase its radial diameter. When the first support ball 201 and the second support ball 202 are in an expanded state, their expanded size can be adjusted by retracting and releasing the first pull wire 301 and the second pull wire 302 to adjust the supporting force of the first support ball 201 and the second support ball 202.

[0054] Example 2

[0055] This embodiment provides a neural intervention anchoring guidewire, such as Figure 1As shown, it includes a core wire 100, the distal end of the core wire 100 is axially connected to the first support ball 201 and the second support ball 202 in sequence, and the first support ball 201 is located at the distal end of the second support ball 202, the distal end of the core wire 100 is flush with the distal end of the first support ball 201, and the core wire 100 adopts a hollow structure, and its proximal end and distal end are connected to form an inner cavity, and the first pull wire 301 and the second pull wire 302 are arranged in the inner cavity, wherein the first pull wire 301 is connected to the distal end of the first support ball 201, and the second pull wire 302 is connected to the distal end of the second support ball 202, and the first pull wire 301 and the second pull wire 302 do not interfere with each other.

[0056] In this embodiment, when the first pull wire 301 or the second pull wire 302 is pulled toward the proximal direction, the distal end of the first support ball 201 or the second support ball 202 can be moved closer to the proximal direction, thereby squeezing the first support ball 201 or the second support ball 202, causing it to expand and gradually increase its radial diameter. When the first support ball 201 and the second support ball 202 are in an expanded state, their expanded size can be adjusted by retracting and releasing the first pull wire 301 and the second pull wire 302 to adjust the supporting force of the first support ball 201 and the second support ball 202.

[0057] The difference between this embodiment and embodiment 1 is that Figure 3 As shown, the first support ball 201 and the second support ball 202 are woven from a plurality of nickel-titanium alloy wires. When forming support for the blood vessel wall, the first support ball 201 and the second support ball 202 can be used as filters to filter the blood flow, thereby preventing thrombus fragments generated during the operation from escaping to the distal end of the blood vessel with the blood flow.

[0058] Example 3

[0059] This embodiment provides a neural intervention anchoring guidewire, such as Figure 1 As shown, it includes a core wire 100, the distal end of the core wire 100 is axially connected to the first support ball 201 and the second support ball 202 in sequence, and the first support ball 201 is located at the distal end of the second support ball 202, the distal end of the core wire 100 is flush with the distal end of the first support ball 201, and the core wire 100 adopts a hollow structure, and its proximal end and distal end are connected to form an inner cavity, and the first pull wire 301 and the second pull wire 302 are arranged in the inner cavity, wherein the first pull wire 301 is connected to the distal end of the first support ball 201, and the second pull wire 302 is connected to the distal end of the second support ball 202, and the first pull wire 301 and the second pull wire 302 do not interfere with each other.

[0060] In this embodiment, when the first pull wire 301 or the second pull wire 302 is pulled toward the proximal direction, the distal end of the first support ball 201 or the second support ball 202 can be moved closer to the proximal direction, thereby squeezing the first support ball 201 or the second support ball 202, causing it to expand and gradually increase its radial diameter. When the first support ball 201 and the second support ball 202 are in an expanded state, their expanded size can be adjusted by retracting and releasing the first pull wire 301 and the second pull wire 302 to adjust the supporting force of the first support ball 201 and the second support ball 202.

[0061] This embodiment is further improved on the basis of embodiment 1. Specifically, Figure 3 As shown, heat shrink tubes 400 are provided at both ends of the first support ball 201 and the second support ball 202. The heat shrink tubes 400 are used to fix the first support ball 201 and the second support ball 202 to prevent them from detaching from the core wire.

[0062] Example 4

[0063] This embodiment provides a neural intervention anchoring guidewire, such as Figure 1 As shown, it includes a core wire 100, the distal end of the core wire 100 is axially connected to the first support ball 201 and the second support ball 202 in sequence, and the first support ball 201 is located at the distal end of the second support ball 202, the distal end of the core wire 100 is flush with the distal end of the first support ball 201, and the core wire 100 adopts a hollow structure, and its proximal end and distal end are connected to form an inner cavity, and the first pull wire 301 and the second pull wire 302 are arranged in the inner cavity, wherein the first pull wire 301 is connected to the distal end of the first support ball 201, and the second pull wire 302 is connected to the distal end of the second support ball 202, and the first pull wire 301 and the second pull wire 302 do not interfere with each other.

[0064] In this embodiment, when the first pull wire 301 or the second pull wire 302 is pulled toward the proximal direction, the distal end of the first support ball 201 or the second support ball 202 can be moved closer to the proximal direction, thereby squeezing the first support ball 201 or the second support ball 202, causing it to expand and gradually increase its radial diameter. When the first support ball 201 and the second support ball 202 are in an expanded state, their expanded size can be adjusted by retracting and releasing the first pull wire 301 and the second pull wire 302 to adjust the supporting force of the first support ball 201 and the second support ball 202.

[0065] This embodiment is further improved on the basis of embodiment 2. Specifically, Figure 4 As shown, filter membranes 500 are applied on the surfaces of the first support ball 201 and the second support ball 202. The blood flow is filtered through the filter membranes 500, and thrombus fragments with smaller sizes can be filtered.

[0066] Example 5

[0067] This embodiment provides a neural intervention anchoring guidewire, such as Figure 1 As shown, it includes a core wire 100, the distal end of the core wire 100 is connected to the first support ball 201 and the second support ball 202 in sequence along the axial direction, and the first support ball 201 is located at the distal end of the second support ball 202, and the distal end of the core wire 100 is flush with the distal end of the first support ball 201. The core wire 100 adopts a hollow structure, and its proximal end and distal end are connected to form an inner cavity, such as Figure 5 As shown, a first pull wire 301 and a second pull wire 302 are arranged in the inner cavity, wherein the first pull wire 301 is connected to the distal end of the first support ball 201, and the second pull wire 302 is connected to the distal end of the second support ball 202, and the first pull wire 301 and the second pull wire 302 do not interfere with each other.

[0068] In this embodiment, when the first pull wire 301 or the second pull wire 302 is pulled toward the proximal direction, the distal end of the first support ball 201 or the second support ball 202 can be moved closer to the proximal direction, thereby squeezing the first support ball 201 or the second support ball 202, causing it to expand and gradually increase its radial diameter. When the first support ball 201 and the second support ball 202 are in an expanded state, their expanded size can be adjusted by retracting and releasing the first pull wire 301 and the second pull wire 302 to adjust the supporting force of the first support ball 201 and the second support ball 202.

[0069] This embodiment is further improved on the basis of embodiment 2. Specifically, Figure 5 As shown, a support rod 600 is provided on the inner side of the core wire 100, and the support rod 600 is connected to the proximal end of the second support ball 202. The support rod 600 can be held at the proximal end of the core wire 100, and then the first pull wire 301 is pulled to make the first support ball 201 expand for a second time. At this time, the proximal end of the first pull wire 301 is fixed to the core wire 100 with a fixing clip, so that the first support ball 201 can maintain the supporting force; when the second support ball 202 needs to be adjusted, the core wire 100 acts as a support, and pulling the second pull wire 302 can make the second support ball 202 expand for a second time.

[0070] Example 6

[0071] This embodiment provides a neural intervention anchoring guidewire, which is further improved on the basis of embodiment 1, such as Figure 6 As shown, the difference from Example 1 is that the outer surface of the core wire 100 is provided with a winding wire 101, which is spiral and covers the distal end of the core wire 100, and the proximal end of the winding wire 101 extends to the proximal end of the second support ball 202. By providing the winding wire 101, the support force, controllability and tracking of the anchoring guidewire can be enhanced, so that the doctor or operator can more accurately control the direction and position of the guidewire.

[0072] In summary:

[0073] The present invention improves the radial supporting force of the anchoring guidewire in the blood vessel by increasing the number of supporting balls, thereby providing a more stable fixing effect. By setting the first pull wire 301 and the second pull wire 302, the supporting force of the first support ball 201 and the second support ball 202 can be adjusted to cause secondary expansion.

[0074] In the present invention, the first support ball 201 and the second support ball 202 can be woven from braided wire, and a filter membrane 500 is laid on the surface, so that they can filter blood clots in the blood flow while playing a supporting role.

[0075] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A neural intervention anchoring guidewire, comprising a main guidewire, characterized in that: The main guide wire comprises a core wire, the distal end of the core wire is axially connected to a first support ball and a second support ball in sequence, and when the first support ball and the second support ball are in an expanded state, the expanded sizes thereof are adjustable.

2. A neural intervention anchoring guidewire according to claim 1, characterized in that: The first support ball and the second support ball are controlled by a pull wire, which passes through the core wire and extends to the proximal end of the core wire.

3. A neural intervention anchoring guidewire according to claim 2, characterized in that: The pull wire includes a first pull wire and a second pull wire. When the first pull wire is pulled, the first support ball gradually expands. When the second pull wire is pulled, the second support ball gradually expands.

4. A neural intervention anchoring guidewire according to claim 3, characterized in that: The first pull wire is connected to the distal end of the first support ball, and the second pull wire is connected to the distal end of the second support ball.

5. A neural intervention anchoring guidewire according to any one of claims 1 to 4, characterized in that: The first supporting ball and / or the second supporting ball are woven from a plurality of elastic threads.

6. A neural intervention anchoring guidewire according to any one of claims 1 to 4, characterized in that: The outer surface of the core wire is provided with a winding wire, the winding wire is spiral and covers at least the distal end of the core wire, and the proximal end of the winding wire extends to the proximal end of the second supporting ball.

7. A neural intervention anchoring guidewire according to any one of claims 1 to 4, characterized in that: Heat shrink tubes are provided at both ends of the first supporting ball and / or the second supporting ball, and the heat shrink tubes cover the connection between the first supporting ball and / or the second supporting ball and the core wire.

8. A neural intervention anchoring guidewire according to any one of claims 1 to 4, characterized in that: The distal end of the core wire is located inside the distal end of the first supporting ball.

9. A neural intervention anchoring guidewire according to claim 5, characterized in that: A filter membrane is disposed on the surface of the first support ball and / or the second support ball.

10. A neural intervention anchoring guidewire according to claim 9, characterized in that: A support rod is provided inside the core wire, and the support rod is connected to the proximal end of the second support ball.

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