Multifunctional film output equipment and use method
By setting the blowing components and powder absorbing components in the punch plate of the tablet press, the problem of limited punch plate space of the tablet press is solved, and the lubrication spraying and powder absorption of the upper and lower punches and the inner walls of the middle mold cavity is realized, which solves the problem of the thickness of the tablet press. The problems of sticking and astringent punching in tablet production have expanded the scope of application.
Patent Information
- Application Number
- CN202411716906.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-27
- Publication Date
- 2024-12-31
AI Technical Summary
The existing tablet press has limited space inside the punch plate, making it difficult to install spraying equipment, which makes it difficult to solve the problems of sticking and astringent punching in tablet production.
Design a multi-functional tablet-out device, including a blowing assembly and a powder absorbing assembly, fixed between the punch and the middle mold cavity of the punch press press, and spray lubricating powder on the upper and lower punch and the middle mold through the blowing assembly. The inner wall of the cavity and the powder absorbing assembly absorbs excess powder to solve the problems of sticking and astringent flushing.
Based on the original tablet extraction device, the spraying and vacuuming functions are added, which solves the problems of sticking and astringent flushing in tablet production, expands the scope of application of tablet presses, and maintains the flexibility and easy installation of the device. sex.
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Figure CN119217776A_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the field of pharmaceutical machinery technology, and in particular to a multifunctional tablet discharging device and a method of using the same. Background Art
[0002] Tablet press is the most important equipment for pharmaceutical companies to produce tablets. It can press various granular raw materials into shapes. It is mainly used for mass production of single-layer or double-layer round, special-shaped tablets, sugar tablets, calcium tablets and other tablets. It is widely used in pharmaceutical, chemical, food, electronics and other industries.
[0003] During the tableting process, a small amount of lubricating powder is sprayed on the working end faces of the upper and lower punches respectively. When the upper and lower punches press the material particles, the tablets can be easily separated from the pressed contact surfaces of the upper and lower punches under the action of the lubricating powder after pressing, which effectively solves the problem of sticking to the punches in tablet production.
[0004] During the tableting process, after the tablet is ejected in the ejection section, the lower punch continues to rotate and move downward. At this time, the inner wall of the middle die cavity is exposed, and a small amount of lubricating powder is sprayed on the inner wall of the middle die cavity. After the material particles are pressed and formed in the main pressing process, when they are pushed out of the middle die hole by the lower punch in the tableting process, the friction between the inner wall of the middle die cavity and the outer circular vertical surface of the tablet (ejection force) is greatly reduced under the action of the lubricating powder, and the tablet becomes smooth when ejected from the die, which effectively solves the problem of astringency in tablet production.
[0005] However, the space inside the punching plate of the existing tablet press is limited, and how to set up the spraying equipment inside the punching plate is an urgent problem to be solved. Summary of the invention
[0006] The embodiment of the present application provides a multifunctional tablet discharging device and a method of use, which solves the problem that the space inside the punching plate of the tablet press is small and it is difficult to set up a spraying device.
[0007] In the first aspect, the embodiment of the present application provides a multifunctional tablet discharge device, which is fixedly arranged between the punch of the tablet press and the middle die cavity, and includes a blowing assembly and a tablet discharge blocking rod. The blowing assembly is a hollow cavity, and the two opposite side walls of the cavity are respectively provided with blowing ports, one end of the cavity is closed, and the other end is provided with an air inlet. The tablet discharge blocking rod has one side facing the rotation direction of the tablet press punch to block the tablets ejected from the middle die cavity by the punch; the other side is provided with a blowing assembly. The blowing ports on both sides of the blowing assembly are respectively facing the upper punch and the lower punch of the tablet press punch.
[0008] In one embodiment, the powder suction component is also included. The powder suction component is a hollow cavity, the side wall of the cavity is provided with a powder suction port in the same direction as the opening of the blowing port, the powder suction component is arranged on the side of the blowing component along the rotation direction of the punching disc of the tablet press, one end of the cavity is closed, and the other end is provided with an air outlet.
[0009] Furthermore, the powder suction assembly and the sheet discharging blocking rod are integrally formed.
[0010] In one embodiment, it also includes a powder suction assembly, which includes a front powder suction head, a rear powder suction head and a powder suction tube. The front powder suction head and the rear powder suction head are two independent hollow cavities, one end of the two hollow cavities is closed, and the other end is connected to the powder suction tube, and the side wall of the cavity is provided with a powder suction port with the same opening direction as the blowing port. The front powder suction head and the rear powder suction head are respectively arranged on both sides of the blowing assembly along the rotation direction of the tablet press punching disc. One end of the powder suction tube is respectively connected to the front powder suction head and the rear powder suction head. The other end is provided with an air outlet.
[0011] Furthermore, the front powder suction head and the sheet discharging blocking rod are integrally formed.
[0012] In one embodiment, a lubricating powder atomizing device is also included, which is connected to the air inlet and is used to deliver atomized lubricating powder into the cavity of the spray assembly.
[0013] In one embodiment, the invention further comprises: a control component. The control component comprises a filter pressure reducing valve and a solenoid valve. The filter pressure reducing valve is used to filter the spray airflow. The solenoid valve is used to control the on and off of the spray airflow. The filter pressure reducing valve, the solenoid valve and the spray component are connected through an air pipe.
[0014] In one of the embodiments, it also includes: a negative pressure system for providing negative pressure to the powder suction component cavity.
[0015] In a second aspect, an embodiment of the present application further provides a method for using a multifunctional film output device, using the multifunctional film output device described in any one embodiment of the first aspect, comprising the steps of: Connecting the lubricating powder atomization device to the air inlet, and connecting the negative pressure system to the air outlet; Turn on the lubricating powder atomization equipment and negative pressure system, and start the tablet press; Turn off the tablet press, lubrication powder atomization equipment and negative pressure system.
[0016] In a third aspect, the embodiments of the present application further provide a method for using a multifunctional film output device, using the multifunctional film output device described in any one of the embodiments of the first aspect, comprising the steps of: Connect the control component to the air inlet, and connect the negative pressure system to the air outlet; Turn on the control components and negative pressure system, and start the tablet press; Turn off the tablet press, close the control components and the vacuum system.
[0017] At least one of the above technical solutions adopted in the embodiments of the present application can achieve the following beneficial effects: The present application is optimized and designed based on the structure of the original tablet discharging baffle rod. The device's external dimensions and installation method are the same as the original tablet discharging device, that is, it is also installed and fixed on the feeder. In addition to satisfying the basic function of guiding tablet discharging during tablet production, it can also connect to an external lubricating powder atomization device to achieve the spraying of lubricating powder on the upper and lower punches and the inner wall of the middle mold cavity during the production process, thereby solving the problems of sticking and astringent punches during tablet production and expanding the scope of application of material particles for tablet press tablet production. The installation method and installation space of the present application are the same as the original tablet discharging device, and can be flexibly replaced without modification, satisfying the basic functions of the tablet discharging device. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] The drawings described herein are used to provide a further understanding of the present application and constitute a part of the present application. The illustrative embodiments of the present application and their descriptions are used to explain the present application and do not constitute an improper limitation on the present application. In the drawings: Figure 1 It is a schematic diagram of the tablet pressing process flow of the tablet pressing machine in the prior art; Figure 2 It is a structural schematic diagram of a tablet discharging device of a tablet press in the prior art; Figure 3 This is a schematic diagram of the installation of a tablet discharging device of a tablet press in the prior art; Figure 4-1 A structural diagram of a multifunctional film output device provided in an embodiment of the present application; Figure 4-2 A schematic diagram of the installation structure of a multifunctional film output device provided in an embodiment of the present application; Figure 5 A structural diagram of a spray assembly provided in an embodiment of the present application; Figure 6 A structural diagram of a powder suction assembly provided in an embodiment of the present application; Figure 7 A schematic diagram of the structure of a connection control component of a multifunctional film output device provided in an embodiment of the present application; Figure 8 A flowchart of a method for using a multifunctional film output device provided in an embodiment of the present application; Fig. 9 A flowchart of another method for using a multifunctional film output device provided in an embodiment of the present application. DETAILED DESCRIPTION
[0019] In order to make the purpose, technical solution and advantages of the present application clearer, the technical solution of the present application will be clearly and completely described below in combination with the specific embodiments of the present application and the corresponding drawings. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present application.
[0020] The tablet pressing process of the tablet press includes feeding, dosing, pre-pressing, main pressing and tablet discharge. The tablet pressing process is completed to obtain the finished tablet. The upper and lower punch dies are driven by the punch plate and move along the upper and lower guide rail assemblies respectively. When the punch moves to the feeding and filling section, the upper punch moves upward to bypass the feeder. At the same time, the lower punch moves downward. The upper surface of the lower punch and the middle die hole form a cavity. The powder particles are filled into the middle die cavity through the feeder to complete the material filling process. After that, the upper punch moves downward and the lower punch moves upward to complete the material dosing process in the dosing section. The pre-pressing process of the material is then completed through the pre-pressing wheel. Then, the material enters the main pressing section to complete the final compression and molding process of the material. The compressed tablet is finally ejected from the working surface of the middle punch plate through the tablet discharge guide rail. Following the rotation of the punch plate assembly, under the action of the friction force with the surface of the middle punch plate, the tablet discharge device guides the tablet along the direction of the tablet discharge baffle rod to the tablet discharge box device to complete all the processes of tablet production. Figure 1 As shown, the tablet pressing process flow chart of the tablet press.
[0021] The tablet discharge device of the tablet press in the prior art generally consists of a tablet discharge baffle rod, a baffle rod bracket and a fastener, such as Figure 2 The tablet discharge baffle is fixed to the baffle rod bracket by fasteners, and the baffle rod bracket is fixed to the tablet press feeder by fasteners, as shown in FIG. Figure 3 shown.
[0022] The technical solutions provided by various embodiments of the present application are described in detail below in conjunction with the accompanying drawings.
[0023] Figure 4-1 A multifunctional tablet discharge device structure diagram provided in an embodiment of the present application is fixedly arranged between the punch head and the middle die cavity of the tablet press punching disc, such as Figure 4-2 As shown, it includes a blowing assembly 11 and a sheet discharging baffle rod (in the figure, the sheet discharging baffle rod and the powder suction assembly are integrally formed).
[0024] The blowing assembly is a hollow cavity, and the two opposite side walls of the cavity are respectively provided with blowing ports, one end of the cavity is closed, and the other end is provided with an air inlet. The blowing ports on both sides of the blowing assembly are respectively facing the upper punch and the lower punch of the tablet press punch.
[0025] The blowing assembly and the sheet discharging blocking rod are fixedly connected via a connecting member 13 .
[0026] The connecting piece is made of stainless steel plate and is used to complete the connection between the spraying component and the powder suction component. The mounting hole of the connecting piece is designed as a long slot structure and can be adjusted according to the actual spraying situation.
[0027] The long slot fixing hole on the connecting part in the component can adjust the spraying distance of the spraying component from the upper punch and the middle mold plate according to the size of the spraying airflow required on the upper and lower sides, so as to achieve the best airflow spraying effect.
[0028] Furthermore, the connecting piece is used to connect the device described in the present application to the support of the feeder of the tablet press. The internal blowing assembly of the device is connected and fastened to the tablet discharge baffle rod by the fastener 14, and the device described in the present application is also connected and fastened to the feeder by the fastener.
[0029] Further, the connecting piece is used to connect the support between the device described in the present application and the feeder of the tablet press. The internal blowing assembly of the device is connected and fastened to the sheet discharging baffle rod by the fastener 14, and the device described in the present application is also connected and fastened to the feeder by the fastener. Further, the connecting piece is used to connect the support between the device described in the present application and the feeder of the tablet press. The internal blowing assembly of the device is connected and fastened to the sheet discharging baffle rod by the fastener, and the device described in the present application is also connected and fastened to the feeder by the fastener.
[0030] Furthermore, if Figure 5 As shown, the blowing assembly includes a connecting pipe 111 and a blowing head 112 .
[0031] The interior of the blowing head is a cavity structure, and the air inlet 113 at one end is connected to the outside through a connecting pipe, and a blowing port is arranged on the side wall of the blowing head.
[0032] The spray port can be selected to be hole-shaped or strip-shaped. Since the spray port is used to evenly spray the atomized Ruihua powder on the working end faces of the upper and lower punches and the inner wall of the middle mold wall, preferably, the spray port is a strip-shaped through hole opened along the length direction of the strip-shaped spray head.
[0033] For example, the connecting pipe is made of a stainless steel pipe with a standard diameter and is used to complete the connection with external equipment.
[0034] The blowing head is made of stainless steel bending and welding, and has a cavity structure inside. One side wall of the blowing head cavity is provided with an upper blowing port 114 in the shape of a long groove strip, which is used to spray or spray the lubricating powder on the upper punch working end face. The opposite side of the upper blowing port is also designed with a lower blowing port 115 in the shape of a long groove strip, which is used to spray or spray the lubricating powder on the lower punch working end face and the inner wall of the middle die cavity. Preferably, the lengths of the upper and lower blowing ports both cover the maximum tablet size of the tablet press, and the center position of the blowing port is consistent with the center of the die cavity in the punch disk of the tablet press, ensuring that the lubricating powder can be sprayed evenly and can meet the production of tablets of all sizes.
[0035] For example, the spraying distance between the spray head and the working end faces of the upper and lower punches is adjusted to achieve the best spraying effect of the lubricating powder.
[0036] The air inlet on the blowing assembly is connected to an external air source through an air pipe. Under the action of the airflow blown by the external air source, the working end faces of the upper and lower punches, the steps on the working cylindrical surface of the upper punch, the upper end face of the middle die, the working surface of the middle punch plate and the residual dust attached to the non-working surface of the upper punch are blown in all directions.
[0037] For example, a connecting pipe is fixedly arranged on the air inlet of the blowing assembly, which is connected to an external air source through an air pipe. The strip-shaped upper blowing port on the upper end face of the blowing head cavity is opposite to the working end face of the upper punch, and is responsible for separating the dust adhering to the working end face of the upper punch and the step of the working cylindrical surface from the upper punch rod under the impact of the airflow, and being sucked away and cleaned in time by the dust suction component in the device, thereby completing the cleaning of the dust adhering to the upper punch rod. The strip-shaped lower blowing port on the lower end face of the blowing head cavity is opposite to the working end face of the upper punch, the middle disk surface (including the working surface and the non-working surface), and the upper end face of the middle mold, and the length of the lower blowing port covers the above-mentioned area, and is responsible for separating the upper end face of the middle mold, the working surface of the middle punch disk, and the residual dust attached to the non-working surface of the upper punch die from the above-mentioned surfaces under the impact of the airflow, and being sucked away and cleaned in time by the powder suction component in the device.
[0038] Preferably, the opening in the spray assembly connected to the connecting piece is a long slot fixed hole, and the spray distance of the spray assembly from the upper punch and the middle mold plate can be adjusted according to the size of the spray airflow required on the upper and lower sides, so that the airflow spraying effect reaches the best state.
[0039] The tablet discharging blocking rod has one side facing the rotating direction of the punching disc of the tablet press machine, and is used to block the tablets ejected from the middle die cavity by the punch; and the other side is provided with a blowing component.
[0040] The tablet discharging baffle of the tablet press is fixed on the baffle bracket by fasteners, and the baffle bracket is further fixed on the tablet press feeder by fasteners.
[0041] In one embodiment, a powder suction component 12 is further included. The powder suction component is a hollow cavity, and a powder suction port is provided on the side wall of the cavity in the same direction as the opening of the blowing port. The powder suction component is arranged on the side of the blowing component along the rotation direction of the punching disc of the tablet press, one end of the cavity is closed, and an air outlet is provided at the other end.
[0042] For example, the powder suction component is connected to the tablet press dust suction device through the air outlet and the dust removal pipe, and is used to suck away and clean the excess lubricating powder after the spray component sprays the upper and lower punch working end faces and the inner wall of the middle mold cavity, thereby ensuring the cleanliness of the tablet production process environment and controlling the stability of the lubricating powder content in the tablet.
[0043] Furthermore, the powder suction assembly and the sheet discharging blocking rod are integrally formed.
[0044] For example, the powder suction assembly is made into a strip structure with a certain curvature like the sheet discharging baffle rod, so that the side facing the moving direction of the punching disk serves as a blocking structure of the sheet discharging baffle rod.
[0045] In one embodiment, if Figure 6 As shown, it also includes a powder suction component, which includes a front powder suction head 121, a rear powder suction head 122 and a powder suction tube 123.
[0046] The front powder suction head and the rear powder suction head are two independent hollow cavities, one end of the two hollow cavities is closed, and the other end is connected to the powder suction pipe, and the side wall of the cavity is provided with a powder suction port in the same direction as the opening of the blowing port. The front powder suction head and the rear powder suction head are respectively arranged on both sides of the blowing assembly along the rotation direction of the punching plate of the tablet press. One end of the powder suction pipe is respectively connected to the front powder suction head and the rear powder suction head. The other end is provided with an air outlet.
[0047] like Figure 6 As shown, the front powder suction head has a front powder suction head-upper powder suction port 1211 and a front powder suction head-lower powder suction port 1212; the rear powder suction head has a rear powder suction head-upper powder suction port 1221 and a rear powder suction head-lower powder suction port 1222.
[0048] For example, the powder suction assembly is welded by a front powder suction head, a rear powder suction head and a powder suction pipe, and the interior is a connected cavity structure. The powder suction pipe in the assembly is connected to the internal dust removal system of the tablet press through a pipeline, and the blowing assembly in the multi-functional baffle device of the tablet press is installed and fixed between the front powder suction head and the rear powder suction head.
[0049] Further, the front powder suction head is integrally formed with the sheet-discharging stopper. For example, the front powder suction head is arranged on the side of the blowing assembly facing the rotation direction of the punching disc, and is shaped into a strip structure with a certain curvature like the sheet-discharging stopper, so as to serve as a blocking structure of the sheet-discharging stopper.
[0050] Since the shape of the front powder suction head is consistent with the tablet discharging baffle rod, it can not only complete the tablet discharging guiding function of the standard tablet discharging device, but also complete the work of sucking away the excess lubricating powder after the spraying component sprays the upper and lower punch working end faces and the inner wall of the middle mold cavity, ensuring the cleanliness of the tablet production process environment and controlling the stability of the lubricating powder content in the tablet.
[0051] For example, the powder suction component can also be used to capture the dust blown up by the spray component, and to suck the dust back into the dust removal system of the tablet press through the dust suction pipeline.
[0052] Furthermore, for example, the front powder suction head is made of stainless steel plate, and the shape of the baffle position is the same as the shape of the original standard sheet-discharging baffle rod, which can be used to complete the baffle guiding function of the original standard sheet-discharging baffle rod. The interior of the powder suction head is a cavity structure, and the upper side wall of the cavity is designed with an upper powder suction port in the shape of a long groove strip, which is used to complete the suction and cleaning work of the excess lubricating powder on the upper front side of the spray assembly after the spray assembly sprays the upper punch working end face. The lower side wall of the cavity is also designed with a lower powder suction port in the shape of a long groove strip, which is used to complete the suction and cleaning work of the excess lubricating powder on the lower front side of the spray assembly after the spray assembly sprays the lower punch working end face and the inner wall of the middle mold cavity.
[0053] The rear powder suction head is made of stainless steel plate, with a cavity structure inside. The upper side wall of the cavity is designed with a long groove strip-shaped upper powder suction port, which is used to suck away the excess lubricating powder on the upper rear side of the spray assembly after the spray assembly sprays the upper punch working end face. The lower side wall of the cavity is also designed with a long groove strip-shaped lower dust suction port, which is used to suck away the excess lubricating powder on the lower rear side of the spray assembly after the spray assembly sprays the lower punch working end face and the inner wall of the middle mold cavity.
[0054] The powder suction pipe is made of a stainless steel pipe of standard diameter and is used to complete the connection with the internal dust removal system of the tablet press. The lubricating powder sucked away and cleaned by the front powder suction head and the rear powder suction head is recovered into the powder recovery barrel of the vacuum cleaner under the action of the negative pressure of the tablet press dust removal system.
[0055] The interior of the powder suction component is a connected cavity structure, and the powder suction pipe in the component is connected to the dust removal system inside the tablet press through a pipeline, and the airflow spraying component in the multifunctional baffle device of the tablet press is installed and fixed between the front powder suction head and the rear powder suction head. On the basis of completing the tablet discharge function of the standard tablet discharge device, the airflow spraying component can also complete the suction and recovery of flying dust under the action of the airflow when cleaning the die and the middle plate surface, ensuring the cleanliness of the environment during the production process of double-layer tablets and solving the problems of tablet color mixing, unclear boundary lines, and unevenness.
[0056] For example, the length of the lower dust suction port of the front powder suction head covers the entire middle plate surface. Under the action of suction, most of the dust adhering to the surface of the middle plate surface can be sucked away and cleaned, preventing a large amount of dust from flying around and being inconvenient to capture and clean under the action of the subsequent airflow spraying component. It can also capture the dust blown up by the front side of the airflow spraying component under the action of the airflow spraying of the central mold plate and the end face of the middle mold. The upper dust suction port is used to capture the dust blown up by the front side of the airflow spraying component under the action of the spraying airflow.
[0057] The rear powder suction head can collect and clean the dust raised by the airflow blowing component under the action of suction force, and ensure that the dust of another layer of materials on the upper punch and middle plate surface is completely cleaned before entering the feeder.
[0058] In one embodiment, a lubricating powder atomizing device (not shown in the figure) is also included, which is connected to the air inlet and is used to transport atomized lubricating powder into the cavity of the spraying component.
[0059] It should be noted that, depending on the different requirements for the multifunctional sheet-discharging device described in the present application, the external device connected to the air inlet of the blowing assembly is also different.
[0060] For example, when the multifunctional sheet discharging device described in the present application is required to complete the covering work of the punch working plane on the punch disk and the lubricating powder in the middle die cavity, the air inlet is connected to the lubricating powder atomization device.
[0061] The air inlet on the spray assembly is connected to the external lubricant atomizing device of the tablet press through a pipeline, and is used to transmit and evenly spray the atomized lubricating powder produced by the external lubricant atomizing device onto the working end faces of the upper and lower punches and the inner wall of the middle die cavity.
[0062] For example, Figure 7 As shown, when the multifunctional sheet discharging device of the present application is required to clean the residual dust on the punch working plane of the punch plate and the middle die cavity, in one embodiment, it further comprises: a control component 15. The control component comprises a filter pressure reducing valve 151 and a solenoid valve 152.
[0063] The filter pressure valve is used to filter the spray air flow.
[0064] For example, the filter pressure reducing valve is responsible for filtering the spray airflow to prevent moisture or residue from being sprayed into the material and causing material contamination. Different materials with different characteristics require different spray airflow strengths, and the spray air pressure can be changed by adjusting the pressure regulating knob on the filter pressure reducing valve (the pressure gauge can display it) to ensure that all residual dust is blown away, cleaned and sucked away, and does not fall to other places due to excessive spray airflow.
[0065] The electromagnetic valve is used to control the on and off of the spraying airflow. The filter pressure reducing valve, the electromagnetic valve and the spraying assembly are connected through an air pipe.
[0066] For example, the solenoid valve controls the on and off of the spray air flow, which is controlled by the tablet press PLC system. By clicking a dedicated button on the computer control screen, the start and stop state of the solenoid valve can be switched. When working, the solenoid valve should be opened first and then the tablet press should be operated, and the solenoid valve should be closed after the tablet press is stopped.
[0067] A control component is designed to be added between the air flow spray component and the external air source to assist in completing the filtering, pressure regulation and on-off control of the air flow sprayed by the air flow spray component.
[0068] The control component is composed of a filter pressure reducing valve (with a pressure gauge) and a solenoid valve. The filter pressure reducing valve, the solenoid valve and the air flow spraying component are connected through an air pipe.
[0069] In one of the embodiments, it also includes: a negative pressure system (not shown in the figure) for providing negative pressure to the powder suction component cavity.
[0070] The negative pressure system provides negative pressure for the cavity of the powder suction component, so that the powder suction component can suck away the dust on the punching disc of the tablet press through the upper and lower powder suction ports and send it to the dust removal system of the tablet press.
[0071] During long-term tableting, powders, granules and other materials often have problems of sticking and astringency during the extrusion molding process. Sticking refers to the phenomenon that a thin layer or part of the surface of the tablet adheres to the surface of the upper or lower punch or separates during tableting due to high viscosity, high moisture, tablet shape with inscriptions or extrusion heat, resulting in uneven surface roughness or concave and convex marks on the tablet surface, which has a significant impact on the appearance of the tablet, and even to a certain extent, the tablet identification (such as trademark or tablet identification code) cannot be read. Astringency refers to the phenomenon that when the tablet is ejected from the middle die by the lower punch, due to the low content of lubricant in the material auxiliary materials or the high friction coefficient of the material itself, the friction resistance between the tablet and the middle die arm is too large when ejecting the middle die, resulting in uneven outer circular vertical surface roughness or concave and convex marks, which also has a significant impact on the appearance of the tablet. In severe cases, the tablet may even be crushed when it is ejected from the middle die. The astringency phenomenon will increase the resistance of the lower punch when ejecting the tablet, aggravate the wear of the lower punch and the ejection segment guide rail, and even cause the equipment to fail to work properly.
[0072] The sticking and astringent phenomena are extremely difficult to solve. Usually, the sticking phenomenon is alleviated by adjusting the formula and process and special treatment of the mold surface, but the effect is not good. At present, the most effective way to solve the sticking and astringent problems is to spray a small amount of lubricating powder on the working end faces of the upper and lower punches and the inner wall of the middle mold during the tableting process. For example, spraying magnesium stearate lubricating powder. Magnesium stearate is a white, sand-free fine powder. It is an additive that is widely used in medicines and health products. It has the functions of lubrication and flow aid. It is mainly used to make lubricants and flow aids for tablet production material particles. The material particles made with magnesium stearate also have good fluidity and can effectively prevent adhesion and agglomeration between material particles.
[0073] During the tableting process, a small amount of lubricating powder is sprayed on the working end faces of the upper and lower punches respectively. When the upper and lower punches press the material particles, the tablets can be easily separated from the pressed contact surfaces of the upper and lower punches under the action of the lubricating powder after pressing, which effectively solves the problem of sticking to the punches in tablet production.
[0074] During the tableting process, after the tablet is ejected in the ejection section, the lower punch continues to rotate and move downward. At this time, the inner wall of the middle die cavity is exposed, and a small amount of lubricating powder is sprayed on the inner wall of the middle die cavity. After the material particles are pressed and formed in the main pressing process, when they are pushed out of the middle die hole by the lower punch in the tableting process, the friction between the inner wall of the middle die cavity and the outer circular vertical surface of the tablet (ejection force) is greatly reduced under the action of the lubricating powder, and the tablet becomes smooth when ejected from the die, which effectively solves the problem of astringency in tablet production.
[0075] In order to complete the micro-spraying of lubricating powder on the working end faces of the upper and lower punches and the inner wall of the middle die cavity, the device described in this application is designed. The design is optimized based on the structure of the original sheet discharging baffle. The external dimensions and installation method of the multi-functional sheet discharging device are the same as those of the original sheet discharging device, that is, it is also installed and fixed on the feeder. In addition to meeting the basic function of guiding the tablet production, it can also be connected to an external lubricating powder atomization device to achieve the spraying of lubricating powder on the upper and lower punches and the inner wall of the middle die cavity during the production process, thereby solving the problems of sticking and astringent punches in the tablet production process and expanding the scope of application of material particles in tablet press tablet production.
[0076] Figure 8 A method for using a multifunctional tablet discharging device provided in an embodiment of the present application is specifically for preventing sticking and astringency of a tablet press, using the multifunctional tablet discharging device described in any one embodiment of the first aspect, comprising the steps of: Step 210, connecting the lubricating powder atomization device to the air inlet, and connecting the negative pressure system to the air outlet; Step 220, start the lubricating powder atomization device and the negative pressure system, and start the tablet press; Step 230: Turn off the tablet press, the lubricating powder atomization device and the negative pressure system.
[0077] Using the method described in this application to prevent sticking and astringency in a tablet press has the following advantages: Advantage 1: The installation method and installation space are the same as the original film discharge device, and can be flexibly replaced without modification to meet the basic functions of the film discharge device.
[0078] Advantage 2: Through the external lubricating powder atomization device and the internal dust removal system, the more difficult problems of sticking and astringency in the tablet press production process can be effectively solved, expanding the application range of material particles in the tablet press tablet production.
[0079] Advantage 3: The powder suction component of the device surrounds the spray component on both sides, which can completely suck away and clean up the excess lubricating powder in the spray component, ensuring the cleanliness of the production process environment and the stability of the lubricating powder content inside the tablet.
[0080] Advantage 4: The dust suction pipe and the blowing connection pipe of the device are plugged into standard hoses, which are easy to disassemble and assemble.
[0081] Advantage 5: The device has a simple structure and is made of standard profiles, with low processing costs.
[0082] The main working process of the double-layer tablet press includes the filling, dosing, and pre-pressing of the first layer of materials, and the filling, dosing, main pressing, and tableting of the second layer of materials. The upper and lower punches are driven by the punch plate and move clockwise or counterclockwise along the upper and lower guide rails respectively. When the punch moves to the first layer filling section, the upper punch moves upward to bypass the first layer material feeder. At the same time, the lower punch moves downward, and the upper surface of the lower punch and the middle die hole form a cavity. The powder particles are filled into the middle die cavity through the feeder to complete the filling process of the first layer of materials. After that, the upper punch moves downward, and the lower punch moves upward and passes through the first side main pressing wheel to complete the pre-pressing process of the first layer of materials. Then, the filling, main pressing, and other processes of the second layer of materials are completed in the same way. The double-layer tablets after the main pressing are pushed out of the working surface of the middle punch plate through the tablet discharge guide rail, and the double-layer tablets are introduced into the tablet discharge device by the tablet discharge device. After the punch plate rotates one circle, each punch completes all the processes of pressing the double-layer tablets.
[0083] After a long period of operation, the tablet press will accumulate some residual dust on the working surface of the middle punch plate and the working cylindrical step of the upper punch. If the material particles have strong adhesion and high viscosity, the material will adhere to the working end surfaces of the upper and lower punches when it is pressed and formed, and follow the upper and lower punches into the subsequent tableting process, resulting in color mixing of the double-layer tablets. The key to measuring the success or failure of the production of double-layer tablets by a tablet press is whether the boundary line of the two layers of the pressed double-layer tablets is clear and neat, and whether there is any color mixing. For the production of double-layer tablets, the dust attached to the working end surfaces of the upper and lower punches and the dust remaining on the two layers of the middle punch plate cannot be cleaned and sucked away in time. As the running time of the tablet press increases, the residual dust will increase, aggravating the cross-contamination between the two layers of materials. This is the main reason for the color mixing, unclear and uneven boundary lines of the two layers of double-layer tablets.
[0084] The dust generated by the tablet press during operation is mainly caused by the following three situations: ① There is generally a gap of less than or equal to 0.1 mm between the bottom surface of the forced feeder of the tablet press and the working surface of the middle punch disk. The purpose of leaving the gap is to prevent the working surface of the middle punch disk from scratching the bottom surface of the feeder during rotation. Therefore, when the feeder is feeding the middle die cavity, some fine powder in contact with the working surface of the middle punch disk will escape from the feeder from the gap between the bottom surface of the feeder and the working surface of the middle punch disk as the middle punch disk rotates (a certain amount of fine powder will be generated during the forced feeding or granulation process of the material through the feeding impeller). The escaping dust adheres to the working surface of the middle punch disk and rotates to the next process. ② When the middle die is installed in the middle die installation hole of the middle punch disk, the upper end surface of the middle die is about 0.03 mm lower than the working surface of the middle punch disk, which will create another gap. During the feeding process of the middle die cavity, some dust will remain in the gap between the upper end surface of the middle die and the working surface of the middle punch disk, and rotate to the next process as the punch disk rotates. ③ When the upper and lower punches of the tablet press simultaneously enter the first layer of main pressing wheel to complete the pre-pressing process or enter the second layer of main pressing wheel to complete the main pressing process, the material in the middle die cavity will be quickly squeezed by the upper and lower punches. The air between the material particles in the middle die cavity will be discharged through the gap between the non-working surface of the upper punch and the inner side of the middle die hole as the material is compressed. Some dust is also discharged with the air. Some of this dust falls on the working surface of the middle punch plate, and some of it will adhere to the non-working surface of the upper punch step, and rotate to the next process with the punch plate and the upper punch.
[0085] Traditional double-layer tablet presses generally use a dust suction device and a tablet discharge device with a dust suction function to remove residual dust. This powder removal method can remove and suck away some of the residual dust on the working surface of the middle punch and the upper end surface of the middle die, but some of the residual dust will still rotate with the middle punch to the next process. The dust attached to the non-working surface of the upper punch will not be removed and sucked away because it is far away from the dust suction device. After the tablet press has been running for a long time, the residual dust will gradually increase, resulting in aggravated cross-contamination of materials on both sides, resulting in mixed colors of the two layers of double-layer tablets, unclear and uneven dividing lines.
[0086] Double-layer tablets are generally made by filling different types of particles into the middle die hole in order. The weight of each layer of the double-layer tablet is controlled by a separate quality control device and material frame. Double-layer tablets have the following advantages: ① It can separate drugs that may cause incompatibility; ② The amount of sustained-release and immediate-release components in the tablet can be adjusted manually; ③ Drug particles of different colors are easy to distinguish and have beautiful appearance. The tablet press will generate dust during operation. As the tablet press runs longer, the residual dust will increase, aggravating the cross-contamination between the two layers of materials, and causing the double-layer tablets to mix colors, unclear and uneven boundaries. If the dust generated during the operation of the tablet press is not removed in time, the advantages of the double-layer tablets will eventually be lost.
[0087] Fig. 9 A method for using a multifunctional tablet discharging device is also provided in an embodiment of the present application, specifically for cleaning a punching plate of a tablet press, using the multifunctional tablet discharging device described in any one of the embodiments of the first aspect, comprising the steps of: Step 310, connecting the control component to the air inlet, and connecting the negative pressure system to the air outlet; For example, first connect the pipe joint in the device to the dust removal negative pressure system through a steel hose, connect the external air source to the filter pressure reducing valve in the auxiliary control system of the device through the air pipe, and adjust the air pressure of the filter pressure reducing valve to 0.1-0.3MPa. Enter the computer control interface of the tablet press, click the exclusive button on the control screen, and pre-check the operation of the solenoid valve and the airtightness of the spraying air path. Adjust the distance between the airflow spray component and the upper punch and the middle plate spraying distance to achieve the best spraying effect. Under the strong suction of the negative pressure system, the dust suction component will promptly capture and remove the dust blown up by the airflow spray component.
[0088] Step 320, start the control component and the negative pressure system, and start the tablet press; When tableting: first open the solenoid valve and negative pressure system, then start the tablet press.
[0089] Step 330: Turn off the tablet press, and turn off the control component and the negative pressure system.
[0090] When shutting down: first stop the tablet press, then close the solenoid valve and the dust removal negative pressure system. When pressing materials with different characteristics, observe the cleaning of residual dust on the working surface of the middle punch plate and the upper punch surface (working end surface and non-working step surface) after the airflow is blown, and adjust the air pressure of the filter pressure reducing valve appropriately. If the blowing air pressure is too small, the residual dust will not be blown away. If it is too large, the dust will be blown to other places, which will cause cross-contamination of the two layers of materials. Adjust it to blow away the residual dust without blowing it to other places. In this way, the double-layer tablet press equipped with this device, with the mutual cooperation of the various components of the device, greatly avoids the cross-contamination of the two layers of materials, so that even if the tablet press runs for a long time, the pressed double-layer tablets will not have mixed colors, unclear boundaries, and unevenness of the two layers of tablets.
[0091] Using the method described in this application to clean the punching plate of a tablet press has the following advantages: Advantage 1: The device has multiple functions. It can not only meet the basic function of the tablet discharging device, but also easily realize the other two extended functions by changing the connection between the device and the outside, so that the tablet press can be used for the production and pressing of more characteristic material particles.
[0092] Advantage 2: The powder suction component of the device surrounds the airflow blowing component in front and back, which can effectively and thoroughly remove the flying dust. It ensures that the tablet press using this device will not have the problem of mixed color of the two layers of tablets, unclear boundary lines, and unevenness after a long period of cumulative production. This device is a forced powder cleaning by airflow, which greatly improves the quality of pressed double-layer tablets.
[0093] Advantage 3: The control system of the device is controlled by the tablet press computer, and the control operation is simple.
[0094] Advantage 4: The device has a wide range of applications. By adjusting the air pressure of the filter pressure reducing valve, it can adapt to the compression of double-layer tablets of materials with different characteristics; by changing the shape of the adjustment device, it can adapt to tablet presses of different models.
[0095] Advantage 5: The device has a simple structure, is easy to disassemble and maintain, uses common components, and has a low cost.
[0096] The above is only an embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application may have various changes and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application should be included in the scope of the claims of the present application.
Claims
1. A multifunctional tablet discharge device, fixedly arranged between the punch of the tablet press and the middle die cavity, characterized in that: It includes a blowing assembly and a sheet discharging stopper rod; The blowing assembly is a hollow cavity, and two opposite side walls of the cavity are respectively provided with blowing ports, one end of the cavity is closed, and the other end is provided with an air inlet; The tablet-discharging blocking rod has one side facing the rotation direction of the punching disc of the tablet press, and is used to block the tablets ejected from the middle die cavity by the punch; and a blowing component is arranged on the other side; The blowing ports on both sides of the blowing assembly are respectively facing the upper punch and the lower punch of the punching plate of the tablet press.
2. The multifunctional film output device according to claim 1, characterized in that: It also includes a powder suction component; The powder suction component is a hollow cavity, and the side wall of the cavity is provided with a powder suction port in the same direction as the opening of the blowing port. The powder suction component is arranged on the side of the blowing component along the rotation direction of the tablet press punching disc. One end of the cavity is closed and the other end is provided with an air outlet.
3. The multifunctional film output device according to claim 1, characterized in that: It also comprises a powder suction component, which comprises a front powder suction head, a rear powder suction head and a powder suction tube; The front powder suction head and the rear powder suction head are two independent hollow cavities, one end of the two hollow cavities is closed, and the other end is connected to the powder suction pipe, and the side wall of the cavity is provided with a powder suction port in the same opening direction as the blowing port; The front powder suction head and the rear powder suction head are respectively arranged on both sides of the blowing assembly along the rotation direction of the punching disc of the tablet press; One end of the powder suction pipe is respectively connected to the front powder suction head and the rear powder suction head; The other end is provided with an air outlet.
4. The multifunctional film output device according to claim 2, characterized in that: The powder suction assembly and the sheet discharging blocking rod are integrally formed.
5. The multifunctional film output device according to claim 3, characterized in that: The front powder suction head and the sheet discharging blocking rod are integrally formed.
6. The multifunctional film output device according to claim 1, characterized in that: It also includes a lubricating powder atomizing device connected to the air inlet for conveying atomized lubricating powder into the cavity of the spraying assembly.
7. The multifunctional film output device according to claim 1, characterized in that: Also includes: control components; The control assembly comprises a filter pressure reducing valve and a solenoid valve; The filter pressure valve is used to filter the jet airflow; The solenoid valve is used to control the on and off of the spraying air flow; The filter pressure reducing valve, the solenoid valve and the spray assembly are connected through an air pipe.
8. The multifunctional film output device according to claim 2 or 3, characterized in that: It also includes: a negative pressure system, which is used to provide negative pressure for the cavity of the powder suction component.
9. A method for using a multifunctional film output device, characterized in that: Using the multifunctional film output device according to any one of claims 1 to 8 comprises the steps of: Connecting the lubricating powder atomization device to the air inlet, and connecting the negative pressure system to the air outlet; Turn on the lubricating powder atomization equipment and negative pressure system, and start the tablet press; Turn off the tablet press, lubrication powder atomization equipment and negative pressure system.
10. A method for using a multifunctional film output device, characterized in that: Using the multifunctional film output device according to any one of claims 1 to 8 comprises the steps of: Connect the control component to the air inlet, and connect the negative pressure system to the air outlet; Turn on the control components and negative pressure system, and start the tablet press; Turn off the tablet press, close the control components and the vacuum system.
