Atomization product, application method and application thereof, and preparation method of porous material

Abstract

The invention relates to an atomizing product. The atomizing product comprises an atomizing agent, a functional substance and an atomizer, the atomizing agent can generate atomizing agent aerosol after being atomized; the atomizer comprises a first cavity and a second cavity which are separated by an isolation mechanism, the atomizing agent is loaded in the first cavity, the functional substance is loaded in the second cavity, and the isolation mechanism limits the atomizing agent in the first cavity; the second cavity is further provided with an air suction port, the atomizing agent aerosol penetrates through the isolation mechanism from the first cavity to enter the second cavity and makes contact with the functional substance to form aerosol carrying the functional substance, and the aerosol carrying the functional substance is discharged from the air suction port.

Description

Technical Field

[0001] The present application relates to the technical field of atomization products, and in particular to an atomization product and an application method and application thereof, and a method for preparing a porous material. Background Art

[0002] Atomization technology is an operation technology that disperses liquid into tiny droplets through a nozzle or high-speed airflow. It has been widely used in the medical and tobacco fields. In the medical field, for example, solid or liquid drugs can be atomized into tiny particles through a medical atomizer, and the drugs are absorbed by the respiratory tract and lungs through inhalation, thereby achieving the purpose of painless, rapid and effective treatment of respiratory and nervous system diseases. In the tobacco field, atomization technology is also an important part of the e-cigarette industry. For example, in heat-not-burn (HNB), the smoking section of the cigarette can produce atomized aerosol after heating. Summary of the invention

[0003] Based on this, it is necessary to provide an atomization product and its application method and application which can improve the performance stability of functional substances and thus have a better suction effect.

[0004] Furthermore, it is necessary to provide a method for preparing a porous material with physical adsorption capacity.

[0005] An embodiment of the present application provides an atomization product, including: an atomizer, a functional substance, and an atomizer;

[0006] The atomizer can generate an atomizer aerosol after atomization;

[0007] The atomizer comprises a first cavity and a second cavity separated by an isolation mechanism, the atomizer is loaded in the first cavity, the functional substance is loaded in the second cavity, and the isolation mechanism confines the atomizer in the first cavity;

[0008] The second cavity is also provided with an air inlet, and the aerosol of the atomizer passes through the isolation mechanism from the first cavity into the second cavity and contacts with the functional substance to form an aerosol carrying the functional substance, and the aerosol carrying the functional substance is discharged from the air inlet.

[0009] In one embodiment, the aerosolizing agent includes an inert liquid that can be atomized to form an aerosol;

[0010] Optionally, the atomization temperature of the atomizer is ≤250°C;

[0011] Optionally, the atomizer includes one or more of water, propylene glycol, glycerin, limonene and glyceride substances;

[0012] Further optionally, the glyceride substance includes one or more of triacetin and caprylic decanoic acid glyceride.

[0013] In one embodiment, the functional substance includes at least one of a substance having biological activity and a substance having sensory properties;

[0014] Optionally, the biologically active substance includes one or more of ketotifen, rimantadine and nicotine;

[0015] Optionally, the substance with organoleptic properties includes one or more of essences, essential oils, cooling agents and sweeteners.

[0016] In one embodiment, the second cavity is further loaded with a first solid carrier, and the functional substance is loaded on the first solid carrier;

[0017] Optionally, the loading amount of the functional substance is ≥ 0.05%.

[0018] In one embodiment, a second solid carrier is further loaded in the first cavity, and the atomizer is loaded on the second solid carrier;

[0019] Optionally, the loading amount of the aerosol agent is ≥20%.

[0020] In one embodiment, the first solid carrier and the second solid carrier are each independently selected from a porous material having physical adsorption capacity;

[0021] Optionally, the water content of the porous material having physical adsorption capacity is ≤8%;

[0022] Optionally, the chemical composition of the porous material having physical adsorption capacity includes one or more of starch and cellulose;

[0023] Further optionally, the cellulose includes one or more of natural plant cellulose, microcrystalline cellulose, methyl cellulose and hydroxypropyl methyl cellulose.

[0024] In one embodiment, the method of loading the functional substance on the first solid carrier comprises the following steps: spraying a liquid containing the functional substance on the first solid carrier;

[0025] The method of loading the atomizer on the second solid carrier comprises the following steps: spraying the liquid containing the atomizer on the second solid carrier.

[0026] In one embodiment, the isolation mechanism has at least one air hole, and the diameter of the air hole is smaller than the diameters of the first solid carrier and the second solid carrier.

[0027] In one of the embodiments, during the process in which the aerosol of ...

[0028] In one embodiment, the temperature of the aerosol carrying the functional substance discharged from the inhalation port is ≤ 40°C.

[0029] An embodiment of the present application also provides a method for applying the atomized product as described in any of the above embodiments, comprising the following steps:

[0030] Atomizing the atomizer to generate the atomizer aerosol;

[0031] Inhalation is performed through the inhalation port, and the atomizer aerosol passes through the isolation mechanism from the first cavity into the second cavity and contacts with the functional substance to form an aerosol carrying the functional substance, and the aerosol carrying the functional substance is discharged from the inhalation port.

[0032] One embodiment of the present application also provides an application of the atomization product described in any of the above embodiments in the field of medical products or in the field of tobacco.

[0033] An embodiment of the present application also provides a method for preparing a porous material with physical adsorption capacity, comprising the following steps: mixing the chemical components of the porous material with physical adsorption capacity with water, granulating the mixture, and drying the mixture.

[0034] The present application provides an atomization product, including an atomizer, a functional substance and an atomizer. The atomizer and the functional substance are located in different cavities of the atomizer and are isolated by an isolation mechanism. In daily product storage, the atomizer and the functional substance do not contact each other. During inhalation, the atomizer aerosol passes through the isolation mechanism from the first cavity of the atomizer into the second cavity. The temperature of the atomizer aerosol gradually decreases during the flow process, and when in contact with the functional substance, it has a relatively low suitable temperature to ensure the stability of the performance of the functional substance, avoid the adverse effects such as long-term contact between the atomizer and the functional substance, or deterioration of the functional substance due to excessively high atomization temperature, so that the performance of the functional substance is more stable and controllable, and the suction effect of the atomization product can be greatly improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] Figure 1 Schematic diagram of the structure of an atomizer in one embodiment.

[0036] Figure 2 It is a schematic diagram of the structure of the atomization product in Examples 1, 2, 3, and 6.

[0037] Figure 3It is a schematic diagram of the structure of the atomization product in Examples 4, 5, 7 and 8.

[0038] Figure 4 This is a schematic diagram of the structure of the atomization product in Comparative Example 1.

[0039] Figure 5 This is a schematic diagram of the structure of the atomization product in Comparative Example 2.

[0040] Figure 6 This is a schematic diagram of the structure of the atomization product in Comparative Example 3.

[0041] Description of reference numerals:

[0042] 10: atomizer; 110: isolation mechanism; 120: first cavity; 130: second cavity; 140: air inlet; 150: filtering mechanism; 20: first solid carrier; 30: functional substance; 40: atomizer; 50: second solid carrier. DETAILED DESCRIPTION

[0043] For ease of understanding of the application, the application will be described more fully below in conjunction with embodiments and accompanying drawings. The application can be implemented in many different forms and is not limited to the embodiments described in the application. On the contrary, the purpose of providing these embodiments is to make the understanding of the disclosure of the application more thorough and comprehensive.

[0044] Unless otherwise defined, all technical and scientific terms used in this application have the same meaning as those commonly understood by those skilled in the art to which this application belongs. The terms used herein in the specification of this application are only for the purpose of describing specific embodiments and are not intended to limit this application. The term "and / or" used in this application includes any and all combinations of one or more related listed items.

[0045] In the present application, the technical features described in an open manner include closed technical solutions composed of the listed features, and also include open technical solutions containing the listed features.

[0046] An embodiment of the present application provides an atomization product, including: an atomizer, a functional substance, and an atomizer;

[0047] The nebulizer can generate nebulizer aerosol after being nebulized;

[0048] The atomizer comprises a first cavity and a second cavity separated by an isolation mechanism, the atomizer is loaded in the first cavity, the functional substance is loaded in the second cavity, and the isolation mechanism confines the atomizer in the first cavity;

[0049] The second cavity is also provided with an air inlet, and the aerosol of the atomizer passes through the isolation mechanism from the first cavity into the second cavity and contacts with the functional substance to form an aerosol carrying the functional substance, and the aerosol carrying the functional substance is discharged from the air inlet.

[0050] The present application provides an atomization product, including an atomizer, a functional substance and an atomizer. The atomizer and the functional substance are located in different cavities of the atomizer and are isolated by an isolation mechanism. In daily product storage, the atomizer and the functional substance do not contact each other. During inhalation, the atomizer aerosol passes through the isolation mechanism from the first cavity of the atomizer into the second cavity. The temperature of the atomizer aerosol gradually decreases during the flow process, and when in contact with the functional substance, it has a relatively low suitable temperature to ensure the stability of the performance of the functional substance, avoid the adverse effects such as long-term contact between the atomizer and the functional substance, or deterioration of the functional substance due to excessively high atomization temperature, so that the performance of the functional substance is more stable and controllable, and the suction effect of the atomization product can be greatly improved.

[0051] Furthermore, the atomizer provided by the present application has a simple structure and can be made into a product with a smaller volume, which is easy to carry, convenient to use, and highly private.

[0052] In one embodiment, the aerosolizing agent includes an inert liquid that can be atomized to form an aerosol.

[0053] Optionally, the atomization temperature of the atomizer is ≤250°C.

[0054] Optionally, the atomizer includes one or more of water, propylene glycol, glycerin, limonene and glyceride substances.

[0055] Further optionally, the glyceride substance includes one or more of triacetin and caprylic decanoic acid glyceride.

[0056] In one embodiment, the functional substance includes at least one of a substance having biological activity and a substance having sensory properties.

[0057] Bioactive substances refer to substances that produce biological effects on the inhaler after inhalation. In the medical field, bioactive substances can be, for example, drugs that have the effect of preventing or treating diseases, such as ketotifen, which can be used to treat asthma, and rimantadine, which can be used to prevent and treat influenza. In the tobacco field, bioactive substances can be, for example, substances that have a nerve stimulating effect, such as nicotine.

[0058] Substances with sensory properties are substances with characteristics such as smell, color, taste, etc. For example, flavors, essential oils, cooling agents, and sweeteners, etc., wherein cooling agents can be natural cooling agents or artificial cooling agents, such as menthol, etc., artificial cooling agents such as WS-23, etc., and sweeteners such as neotame, sucralose, etc.

[0059] In one embodiment, the second cavity is also loaded with a first solid carrier, and the functional substance is loaded on the first solid carrier. Since the functional substance in the atomized product is used for inhalation into the body, the dosage of the functional substance is generally low, and loading the functional substance in the first solid carrier is more convenient for loading the functional substance in the first cavity. Furthermore, through the form of solid loading, the low content of functional substances in the product can be made more stable and controllable.

[0060] Optionally, the loading amount of the functional substance is ≥ 0.05%. By controlling the loading amount of the functional substance on the first solid carrier within an appropriate range, the dosage of the functional substance carried by the aerosol can be controlled to achieve the desired suction effect. Preferably, the loading amount of the functional substance is 0.1% to 67%.

[0061] In one embodiment, a second solid carrier is also loaded in the first cavity, and the atomizer is loaded on the second solid carrier. In some application scenarios, liquid atomizer directly loaded in the atomizer is prone to leakage, and loading the atomizer on the second solid carrier can effectively avoid leakage.

[0062] Optionally, the loading amount of the atomizer is ≥ 20%. By controlling the loading amount of the atomizer on the second solid carrier within an appropriate range, the atomizer can be controlled to generate enough atomizer aerosol to effectively carry out the functional substance. Preferably, the loading amount of the atomizer is 20% to 67%.

[0063] It can be understood that in the present application, the loading amount of functional substance = mass of functional substance / (mass of functional substance + mass of first solid carrier) × 100%; the loading amount of atomizer = mass of atomizer / (mass of atomizer + mass of second solid carrier) × 100%.

[0064] In one embodiment, the first solid carrier and the second solid carrier are each independently selected from a porous material having physical adsorption capacity. The porous material having physical adsorption capacity can effectively adsorb the functional substance or the atomizer, and during use, compared with a compact structure, can significantly improve the release capacity of the functional substance or the atomizer. Furthermore, compared with a compact structure, when the atomizer is loaded on a second solid carrier with a loose porous structure, the atomizer heats up more evenly during heating and atomization, and can form an atomizer aerosol more quickly and release it from the pores of the second solid carrier; when the functional substance is loaded on a first solid carrier with a loose porous structure, the atomizer aerosol can enter the internal pores of the first solid carrier when passing through the first solid carrier loaded with the functional substance during the process of being sucked out, thereby increasing the contact area between the functional substance and the atomizer aerosol, so that the atomizer aerosol can carry out the functional substance more efficiently, and the functional substance can be released more stably at a lower temperature. The porous material with physical adsorption capacity has a better cooling effect on the atomizer aerosol. Using it as the first solid carrier can help reduce the temperature of the aerosol when it is discharged from the air inlet, thereby avoiding overheating and burns to the human body.

[0065] Optionally, the water content of the porous material with physical adsorption capacity is ≤8%. For the first solid carrier, the lower the water content of the porous material with physical adsorption capacity, the better the adsorption performance of the functional substance can be, and the functional substance is easier to desorb from the first solid carrier after contacting with the atomizer aerosol. If the water content is too high, the desorption performance will be weakened, which will affect the release of the functional substance. For the second solid carrier, the lower the water content of the porous material with physical adsorption capacity, the more conducive it is to reduce the temperature of the aerosol discharged from the air inlet. If the water content is too high, due to the high specific heat capacity of water, the aerosol has a high temperature when it is sucked out and is easy to burn the mouth.

[0066] Optionally, the chemical components of the porous material having physical adsorption capacity include one or more of starch and cellulose.

[0067] Optionally, the cellulose includes one or more of natural plant cellulose, microcrystalline cellulose, methyl cellulose and hydroxypropyl methyl cellulose.

[0068] Preferably, the chemical composition of the porous material with physical adsorption capacity is selected from natural plant cellulose; or, selected from a mixture of natural plant cellulose and other celluloses, and the amount of other cellulose added does not exceed 10% of the total cellulose mass. Although derivatized celluloses such as methyl cellulose and hydroxypropyl methyl cellulose have good adsorption properties, their desorption properties are poor. In contrast, natural plant cellulose can have both good adsorption and desorption properties.

[0069] In one embodiment, the method of loading the functional substance on the first solid carrier comprises the following steps: spraying the liquid containing the functional substance on the first solid carrier. In one embodiment, the method of loading the atomizer on the second solid carrier comprises the following steps: spraying the liquid containing the atomizer on the second solid carrier. After first preparing a solid carrier with a loose porous structure, the atomizer or the functional substance is loaded on the solid carrier. Compared with directly mixing the chemical components of the functional substance and the solid carrier and then granulating, it can ensure the stability of the dosage and performance of the functional substance or the atomizer, and has no effect on the biological performance or sensory characteristics of the functional substance. Moreover, this loading method is more conducive to the dissociation of the atomizer or the functional substance from the solid carrier, and the release is more efficient.

[0070] In one embodiment, the isolation mechanism has at least one air hole, and the diameter of the air hole is smaller than the diameter of the first solid carrier and the second solid carrier. The isolation mechanism can store the atomizer and the functional substance separately. Before use, the two are isolated from each other and do not affect each other, ensuring that the quality of the atomized product is more stable. When in use, the atomizer needs to be atomized at a higher temperature to form an atomized aerosol. Separating the functional substance from the atomizer through the isolation mechanism can avoid the adverse effects of excessive atomization temperature on the performance of the functional substance, such as inactivation of drug efficacy, too fast release, etc. The diameter of the air hole of the isolation mechanism is smaller than the diameter of the first solid carrier and the second solid carrier, which can ensure that the first solid carrier and the second solid carrier are respectively confined to the corresponding cavities, and only the atomizer aerosol can flow between the first cavity and the second cavity.

[0071] In one embodiment, during the process of the atomizer aerosol contacting with the functional substance to form the aerosol carrying the functional substance, the temperature of the atomizer aerosol is ≤150°C. The temperature of the atomizer aerosol is lower than the atomization temperature, but it still has a good ability to carry out the functional substance. Preferably, during the process of the atomizer aerosol contacting with the functional substance to form the aerosol carrying the functional substance, the temperature of the atomizer aerosol is ≤100°C. Further preferably, during the process of the atomizer aerosol contacting with the functional substance to form the aerosol carrying the functional substance, the temperature of the atomizer aerosol is ≤80°C.

[0072] In one embodiment, the temperature of the aerosol carrying the functional substance discharged from the air inlet is ≤40° C. The temperature of the aerosol is highest when the aerosol is generated at the atomization temperature. During the discharge process, the temperature of the aerosol will gradually decrease. The temperature of the aerosol carrying the functional substance discharged from the air inlet is controlled within 40° C. to avoid burns to the human body due to excessive temperature.

[0073] In one embodiment, Figure 1 As shown, a schematic diagram of the structure of an atomizer is provided:

[0074] The atomizer 10 includes a first cavity 120 and a second cavity 130 separated by an isolation mechanism 110 , the atomizer is loaded in the first cavity 120 , and the functional substance is loaded in the second cavity 130 ;

[0075] The second cavity 130 is also provided with an inhalation port 140 , through which air is inhaled, the aerosol of the atomizer passes through the isolation mechanism 110 from the first cavity 120 into the second cavity 130 , and contacts with the functional substance to form an aerosol carrying the functional substance, and the aerosol carrying the functional substance is discharged from the inhalation port 140 .

[0076] It is understandable that the inhalation port 140 can be set in any area in the second cavity 130, and the aerosol carrying the functional substance can be effectively discharged after inhaling through the inhalation port 140. For example, the end of the second cavity 130 away from the isolation mechanism 110, the entire end can be used as the inhalation port 140. It is understandable that after the aerosol carrying the functional substance is discharged from the inhalation port 140, it can enter the human body through the oral cavity and respiratory tract.

[0077] Further, the second cavity 130 is also provided with a filter mechanism 150 in a direction away from the isolation mechanism 110, the air inlet 140 is provided on the filter mechanism 150, and the functional substance is loaded between the isolation mechanism 110 and the filter mechanism 150. During inhalation, the aerosol of the atomizer enters the second cavity 130 and first contacts with the functional substance to form an aerosol carrying the functional substance, and the aerosol carrying the functional substance passes through the filter mechanism 150 and is discharged from the air inlet 140. The filter mechanism 150 can further reduce the temperature of the inlet aerosol to prevent burns to the oral cavity and respiratory mucosa. Further, when the atomizer or functional substance is loaded on a solid carrier, the filter mechanism 150 can also be used to filter solid carrier particles or dust to avoid inhaling dust particles into the oral cavity or respiratory tract, and reduce possible respiratory irritation. Further, the material of the filter mechanism can be, for example, but not limited to, acetate fiber, propionate fiber, and the like.

[0078] An embodiment of the present application also provides a method for applying the atomized product as in any of the above embodiments, comprising the following steps:

[0079] atomizing the atomizing agent to generate an atomizing agent aerosol;

[0080] Inhale through the inhalation port, the atomizer aerosol passes through the isolation mechanism from the first cavity into the second cavity, and contacts with the functional substance to form an aerosol carrying the functional substance, and the aerosol carrying the functional substance is discharged from the inhalation port.

[0081] In one embodiment, the atomizer is atomized by heating. Further, the bottom of the first cavity is heated so that the atomizer in the first cavity reaches an atomization temperature for atomization. Further, the heating source can be located in the first cavity or outside the first cavity.

[0082] One embodiment of the present application also provides the application of the atomization product in any of the above embodiments in the field of medical products or in the field of tobacco. Further, in the field of medical products, the atomization product can be used as a medical atomizer; in the field of tobacco, the atomization product can be used in heat-not-burn cigarettes, electronic cigarettes, and traditional cigarettes.

[0083] An embodiment of the present application also provides a method for preparing a porous material with physical adsorption capacity, comprising the following steps: mixing the chemical components of the porous material with physical adsorption capacity with water, granulating the mixture, and drying the mixture.

[0084] The porous material that is more suitable for the adsorption and desorption of the atomizer or functional substance can be prepared by granulation and drying. The granulation method may include, but is not limited to, rotary extrusion granulation, screw extrusion granulation, fluidized bed granulation, dry granulation, and the like.

[0085] It can be understood that, in other embodiments, the porous material with physical adsorption capacity referred to in the present application can also be selected from natural porous materials with physical adsorption capacity.

[0086] The following is a further detailed description of the atomization product of the present application and its application method, application, and preparation method of the porous material through specific examples. It can be understood that in the following specific examples, unless otherwise specified, all raw materials can be sourced from commercial sources.

[0087] Example 1

[0088] See also Figure 2 :

[0089] (1) Preparation of the first solid carrier 20: 1000 g of medicinal starch was placed in a mixer, and 1000 g of an aqueous solution containing 5% pregelatinized starch was added while stirring. After stirring for a while, an appropriate amount of water was added to adjust the viscosity and humidity of the starch to a moderate level. The starch granules were obtained by granulating using a rotary granulator. The drying conditions were controlled and the granules were screened through a sieve to obtain porous starch granules with a particle size of 20 to 24 mesh and a water content of 5%.

[0090] (2) Loading the functional substance 30 on the first solid carrier 20: 90 g of the porous starch particles prepared in step (1) are placed in a mixer, and 50 g of a hot ethanol solution containing 0.2% ketotifen is sprayed onto the porous starch particles in batches while stirring. The mixture is stirred in the mixer for half an hour at 40° C. to remove the ethanol and cool to room temperature. Then, 10 g of sweet orange essential oil is sprayed onto the porous starch particles at room temperature to prepare a first solid carrier 20 loaded with the functional substance 30 (the ketotifen loading amount is about 0.1%, and the sweet orange essential oil loading amount is about 10%).

[0091] (3) Preparing and applying an atomized product: providing an atomizer 10 , the atomizer 10 comprising a first cavity 120 and a second cavity 130 separated by an isolation mechanism 110 , the second cavity 130 being provided with a filter mechanism 150 in a direction away from the isolation mechanism 110 , and the air inlet 140 being provided on the filter mechanism 150 . Propylene glycol is added as the atomizer 40 into the first cavity 120 of the atomizer 10, 0.1 g of the first solid carrier 20 loaded with the functional substance 30 prepared in step (2) is added into the second cavity 130 of the atomizer 10 and is located between the isolation mechanism 110 and the filtering mechanism 150, the first cavity 120 is heated by an external heat source so that the atomizer 40 reaches an atomization temperature to form an atomizer aerosol, and air is inhaled from the air inlet 140, and the atomizer aerosol is sucked out. During the aspiration process, the atomizer aerosol contacts with the particles of the first solid carrier 20 loaded with the functional substance 30, so that ketotifen and sweet orange essential oil are dissociated from the first solid carrier 20, and ketotifen and sweet orange essential oil are carried out to form an aerosol carrying the functional substance, and the aerosol carrying the functional substance is discharged from the air inlet 140.

[0092] After 20 consecutive suctions, no functional substance 30 was released. After analysis, the collected aerosol contained a total of 0.05 mg of ketotifen, and the total release rate of ketotifen was 50%. After testing with an infrared thermometer, the aerosol temperature from the filter mechanism 150 to the air inlet 140 was about 37 ° C at most, which was not hot. The atomized product provided in this embodiment can achieve oral mucosal and pulmonary administration of ketotifen, and can be used to prevent the onset of asthma in daily use.

[0093] Example 2

[0094] See also Figure 2 :

[0095] (1) Preparation of the first solid carrier 20: 1000 g of natural cellulose with a length and width of less than or equal to 30 μm is placed in a mixer, and 1000 g of an aqueous solution containing 5% pregelatinized starch is added while stirring. After stirring for a while, an appropriate amount of water is added to adjust the viscosity and humidity of the cellulose to a moderate level. After granulation and shaping, cellulose particles are obtained. The drying conditions are controlled and porous cellulose particles with a particle size of 20 to 24 mesh and a water content of 2.5% are screened through a sieve.

[0096] (2) Loading the functional substance 30 on the first solid carrier 20: 90 g of the cellulose particles prepared in step (1) are placed in a mixer, and 100 g of a hot ethanol solution containing 1% ketotifen is sprayed onto the porous cellulose particles in batches while stirring. The mixture is stirred in the mixer at 50° C. for half an hour to remove the ethanol, and then 9 g of sweet orange essential oil is sprayed onto the porous cellulose particles at room temperature to prepare a first solid carrier 20 loaded with the functional substance 30 (the loading amount of ketotifen is 1%, and the loading amount of sweet orange essential oil is 9%).

[0097] (3) Preparing and applying an atomized product: providing an atomizer 10 , the atomizer 10 comprising a first cavity 120 and a second cavity 130 separated by an isolation mechanism 110 , the second cavity 130 being provided with a filter mechanism 150 in a direction away from the isolation mechanism 110 , and the air inlet 140 being provided on the filter mechanism 150 . A mixed solvent of propylene glycol and glycerol (mass ratio 1:1) is added as an atomizer 40 into the first cavity 120 of the atomizer 10, 0.1 g of the first solid carrier 20 loaded with the functional substance 30 prepared in step (2) is added into the second cavity 130 of the atomizer 10 and located between the isolation mechanism 110 and the filtering mechanism 150, the first cavity 120 is heated by an external heat source so that the atomizer 40 reaches an atomization temperature to form an atomizer aerosol, and air is inhaled from the air inlet 140, and the atomizer aerosol is sucked out. During the aspiration process, the atomizer aerosol contacts the first solid carrier 20 loaded with the functional substance 30, so that ketotifen and sweet orange essential oil are dissociated from the first solid carrier 20, and ketotifen and sweet orange essential oil are carried out to form an aerosol carrying the functional substance, and the aerosol carrying the functional substance is discharged from the air inlet 140.

[0098] After 20 consecutive suctions, no functional substance 30 was released. After analysis, the collected aerosol contained a total of 0.7 mg of ketotifen, and the total release rate of ketotifen was 70%. After testing with an infrared thermometer, the aerosol temperature from the filter mechanism 150 to the air inlet 140 was about 32 ° C at most, which was not hot. The atomized product provided in this embodiment can achieve oral mucosal and pulmonary administration of ketotifen, and can be used to prevent and treat asthma in daily use.

[0099] Example 3

[0100] See also Figure 2

[0101] (1) Preparation of the first solid carrier 20: Referring to the method of step (1) of Example 2, the drying conditions were adjusted to prepare porous cellulose particles with a water content of 6%.

[0102] (2) Loading the functional substance 30 on the first solid carrier 20: 90 g of the cellulose particles prepared in step (1) are placed in a mixer, and 100 g of a hot ethanol solution containing 5% rimantadine is sprayed onto the porous cellulose particles in batches while stirring. The solution is dried in an explosion-proof drying oven at 50° C. for half an hour to remove the ethanol. Then, 5 g of peppermint oil is sprayed onto the porous cellulose particles at room temperature to prepare a first solid carrier 20 loaded with the functional substance 30 (the loading amount of rimantadine is 5%, and the loading amount of peppermint oil is 5%).

[0103] (3) Preparing and applying an atomized product: providing an atomizer 10 , the atomizer 10 comprising a first cavity 120 and a second cavity 130 separated by an isolation mechanism 110 , the second cavity 130 being provided with a filter mechanism 150 in a direction away from the isolation mechanism 110 , and the air inlet 140 being provided on the filter mechanism 150 . A mixed solvent of propylene glycol and glycerol (mass ratio 2:3) is added as an atomizer 40 into the first cavity 120 of the atomizer 10, 0.2 g of the first solid carrier 20 loaded with the functional substance 30 prepared in step (2) is added into the second cavity 130 of the atomizer 10 and located between the isolation mechanism 110 and the filtering mechanism 150, the first cavity 120 is heated by an external heat source so that the atomizer 40 reaches an atomization temperature to form an atomizer aerosol, and air is inhaled from the air inlet 140, and the atomizer aerosol is sucked out. During the aspiration process, the atomizer aerosol contacts the first solid carrier 20 loaded with the functional substance 30, so that rimantadine and peppermint oil are dissociated from the first solid carrier 20, and rimantadine and peppermint oil are carried out to form an aerosol carrying the functional substance, and the aerosol carrying the functional substance is discharged from the air inlet 140.

[0104] After 22 consecutive suctions, no functional substance 30 was released after simulating suction by a suction machine (the parameters were set as follows: flow rate 18.3 mL / s, 3 seconds of simulated suction, and then simulated exhalation 5 seconds). After 22 consecutive suctions, no functional substance 30 was released. After analysis, the collected aerosol contained a total of 8 mg of rimantadine, and the total release rate of rimantadine was 80%. According to the infrared thermometer test, the aerosol temperature from the filter mechanism 150 to the air inlet 140 was about 38 ° C at most, which was not hot. The atomized product provided in this embodiment can achieve oral mucosal and pulmonary administration of rimantadine, and can be used for the prevention and treatment of influenza in daily use.

[0105] Example 4

[0106] See also Figure 3 :

[0107] (1) Preparation of the first solid carrier 20 and the second solid carrier 50: Referring to the method of step (1) of Example 2, the natural cellulose is replaced with tea stem powder (containing natural cellulose), and the drying conditions are adjusted to prepare porous tea stem particles with a moisture content of 7.6%.

[0108] (2) Loading the functional substance 30 on the first solid carrier 20: 90 g of the porous tea stem particles prepared in step (1) are placed in a mixer, and 100 g of a hot ethanol solution containing 1% ketotifen is sprayed onto the porous tea stem particles in batches while stirring. The mixture is stirred in the mixer for half an hour at 50° C. to remove the ethanol, and then 9 g of sweet orange essential oil is sprayed onto the porous tea stem particles at room temperature to prepare a first solid carrier 20 loaded with the functional substance 30 (the loading amount of ketotifen is 1%, and the loading amount of sweet orange essential oil is 9%).

[0109] (3) Loading the atomizer 40 onto the second solid carrier 50: Take 10 g of the porous tea stem particles prepared in step (1) and place them in a mixer. At 60°C, 10 g of glycerol is sprayed onto the porous tea stem particles in batches while stirring to obtain a second solid carrier 50 loaded with the atomizer 40 (the loading amount of the glycerol atomizer is 50%).

[0110] (4) Preparing and applying an atomized product: providing an atomizer 10 , the atomizer 10 comprising a first cavity 120 and a second cavity 130 separated by an isolation mechanism 110 , the second cavity 130 being provided with a filter mechanism 150 in a direction away from the isolation mechanism 110 , and the air inlet 140 being provided on the filter mechanism 150 . The second solid carrier 50 loaded with the atomizer 40 prepared in step (3) is added into the first cavity 110 of the atomizer 10, and 0.1 g of the first solid carrier 20 loaded with the functional substance 30 prepared in step (2) is added into the second cavity 130 of the atomizer 10 and is located between the isolation mechanism 110 and the filtering mechanism 150. The first cavity 120 is heated by an external heat source so that the glycerin in the second solid carrier 50 loaded with the atomizer 40 reaches an atomization temperature to form an atomizer aerosol. Inhalation is performed from the air inlet 140, and the atomizer aerosol is sucked out. During the aspiration process, the atomizer aerosol contacts the first solid carrier 20 loaded with the functional substance 30, so that ketotifen and sweet orange essential oil are dissociated from the first solid carrier 20, and ketotifen and sweet orange essential oil are carried out to form an aerosol carrying the functional substance. The aerosol carrying the functional substance is discharged from the air inlet 140.

[0111] After 20 consecutive suctions, no functional substance 30 was released. After analysis, the collected aerosol contained a total of 0.71 mg of ketotifen, and the total release rate of ketotifen was 71%. After testing with an infrared thermometer, the aerosol temperature from the filter mechanism 150 to the air inlet 140 was about 36 ° C at most, which was not hot. The atomized product provided in this embodiment can achieve oral mucosal and pulmonary administration of ketotifen, and can be used to prevent the onset of asthma in daily use.

[0112] Example 5

[0113] See also Figure 3 :

[0114] (1) Preparation of the first solid carrier 20 and the second solid carrier 50: Referring to the method of step (1) of Example 2, the drying conditions were adjusted to prepare porous cellulose particles with a water content of less than 2.5%.

[0115] (2) Loading the functional substance 30 on the first solid carrier 20: 10 g of the porous cellulose particles prepared in step (1) were placed in a mixer, and 10 g of mango essence was sprayed onto the porous cellulose particles in batches while stirring at 50° C. to prepare a first solid carrier 20 loaded with the functional substance 30 (the loading amount of mango essence was 50%).

[0116] (3) Loading the atomizer 40 on the second solid carrier 50: Take 10 g of the porous cellulose particles prepared in step (1) and place them in a mixer. At 60° C., 10 g of atomizer (3 g of propylene glycol, 5 g of glycerol, and 2 g of caprylic acid glyceride) are sprayed onto the porous cellulose particles in batches while stirring to obtain a second solid carrier 50 loaded with the atomizer 40 (the loading amount of the atomizer is 50%).

[0117] (4) Preparing and applying an atomized product: providing an atomizer 10 , the atomizer 10 comprising a first cavity 120 and a second cavity 130 separated by an isolation mechanism 110 , the second cavity 130 being provided with a filter mechanism 150 in a direction away from the isolation mechanism 110 , and the air inlet 140 being provided on the filter mechanism 150 . The second solid carrier 50 loaded with the atomizer 40 prepared in step (3) is added into the first cavity 120 of the atomizer 10. 0.1 g of the first solid carrier 20 loaded with the functional substance 30 prepared in step (2) is added into the second cavity 130 of the atomizer 10 and is located between the isolation mechanism 110 and the filtering mechanism 150. The first cavity 120 is heated by an external heat source so that the atomizer 40 in the second solid carrier 50 reaches an atomization temperature to form an atomizer aerosol. Inhalation is performed from the air inlet 140 and the atomizer aerosol is sucked out. During the aspiration process, the atomizer aerosol contacts the first solid carrier 20 loaded with the functional substance 30, so that the flavor is dissociated from the first solid carrier 20 and the flavor is carried out to form an aerosol carrying the functional substance. The aerosol carrying the functional substance is discharged from the air inlet 140.

[0118] After artificial inhalation, the mango flavor has obvious characteristics, and the balance of each puff is good, and there is no burning or hot feeling in the part contacting the lips, and the overall comfort is good; after testing with an infrared thermometer, the maximum temperature of the aerosol passing through the filter mechanism 150 to the inhalation port 140 is about 35°C, which is not hot to the mouth. The atomization product provided in this embodiment can be applied to heat-not-burn cigarettes, which plays a role in improving the aroma and reducing the aerosol temperature.

[0119] Example 6

[0120] See also Figure 2 :

[0121] (1) Preparation of a first solid carrier 20: The method is the same as step (1) of Example 1, using starch, natural cellulose, tea stem powder and hydroxypropyl methylcellulose as the base material of the first solid carrier, respectively, and controlling the drying conditions to obtain porous starch particles with a water content of 5%, porous natural cellulose particles with a water content of 5%, porous tea stem particles with a water content of 5%, and porous hydroxypropyl methylcellulose particles with a water content of 5%, respectively.

[0122] (2) Loading the functional substance 30 onto the first solid carrier 20: The method is the same as that in step (2) of Example 1, and porous starch particles loaded with the functional substance 30, porous natural cellulose particles loaded with the functional substance 30, porous tea stem particles loaded with the functional substance 30, and porous hydroxypropyl methylcellulose particles loaded with the functional substance are obtained respectively, and the loaded functional substances are all 2% nicotine benzoate.

[0123] (3) Preparing and applying atomized products: The method is the same as that in step (3) of Example 1, wherein porous starch particles loaded with the functional substance 30, porous natural cellulose particles loaded with the functional substance 30, porous tea stem particles loaded with the functional substance 30, and porous hydroxypropyl methylcellulose particles loaded with the functional substance 30 are respectively added into the second cavity 130 of different atomizers 10 and applied.

[0124] After simulated suction by a suction machine (parameters were set as: flow rate 18.3 mL / s, simulated inhalation for 3 seconds, and then simulated exhalation for 5 seconds), the total release rate of nicotine benzoate in the atomized product with porous starch particles as the first solid carrier 20 was 50%, the total release rate of nicotine benzoate in the atomized product with porous natural cellulose particles as the first solid carrier 20 was 73%, and the total release rate of nicotine benzoate in the atomized product with porous tea stem particles as the first solid carrier 20 was 80%. The total release rate of nicotine benzoate in the atomized product with porous hydroxypropyl methylcellulose particles as the first solid carrier 20 was 65%.

[0125] According to the test of infrared thermometer, the maximum aerosol temperature of the atomized product whose first solid carrier 20 is porous starch particles passing through the filtering mechanism 150 to the air inlet 140 is about 50°C, which is not hot. The maximum aerosol temperature of the atomized product whose first solid carrier 20 is porous natural cellulose particles passing through the filtering mechanism 150 to the air inlet 140 is about 52°C, which is not hot. The maximum aerosol temperature of the atomized product whose first solid carrier 20 is porous tea stem particles passing through the filtering mechanism 150 to the air inlet 140 is about 50°C, which is not hot. The maximum aerosol temperature of the atomized product whose first solid carrier 20 is porous hydroxypropyl methylcellulose particles passing through the filtering mechanism 150 to the air inlet 140 is about 39°C, which is not hot.

[0126] Example 7

[0127] See also Figure 3 :

[0128] (1) Preparing a first solid carrier 20 and a second solid carrier 50: Referring to the method of step (1) of Example 4, the drying conditions were adjusted to prepare porous tea stem particles with a water content of 10% as the first solid carrier 20 and porous tea stem particles with a water content of 7.6% as the second solid carrier 50.

[0129] (2) Loading the functional substance 30 on the first solid carrier 20: the same as step (2) of Example 4.

[0130] (3) Loading the atomizer 40 onto the second solid carrier 50: the same as step (3) of Example 4.

[0131] (4) Preparation of atomized product and application: the same as step (4) of Example 4.

[0132] After 20 consecutive suctions, no functional substance 30 was released. After analysis, the collected aerosol contained 0.28 mg of ketotifen in total, and the total release rate of ketotifen was 28%. The atomized product provided in this embodiment can achieve oral mucosal and pulmonary administration of ketotifen, and can be used to prevent the onset of asthma in daily use, but due to the high water content of the first solid carrier 20, the ability of the functional substance 30 to be desorbed from the first solid carrier 20 is weakened, and the total release rate is reduced.

[0133] According to the test of the infrared thermometer, the maximum temperature of the aerosol passing through the filter mechanism 150 to the air inlet 140 is about 40° C., which is not hot to the mouth.

[0134] Example 8

[0135] See also Figure 3 :

[0136] (1) Preparing a first solid carrier 20 and a second solid carrier 50: Referring to the method of step (1) of Example 4, the drying conditions were adjusted to prepare porous tea stem particles with a water content of 10% as the second solid carrier 50 and porous tea stem particles with a water content of 7.6% as the first solid carrier 20.

[0137] (2) Loading the functional substance 30 on the first solid carrier 20: the same as step (2) of Example 4.

[0138] (3) Loading the atomizer 40 onto the second solid carrier 50: the same as step (3) of Example 4.

[0139] (4) Preparation of atomized product and application: the same as step (4) of Example 4.

[0140] After 20 consecutive suctions, no functional substance 30 is released. After analysis, the collected aerosol contains 0.64 mg of ketotifen in total, and the total release rate of ketotifen is 64%. The atomized product provided in this embodiment can achieve oral mucosal and pulmonary administration of ketotifen, and can be used to prevent the onset of asthma in daily use, but due to the high water content of the first solid carrier 20, the ability of the functional substance 30 to be desorbed from the first solid carrier 20 is weakened, and the total release rate is reduced.

[0141] According to the test of the infrared thermometer, the maximum temperature of the aerosol passing through the filter mechanism 150 to the air inlet 140 is 44° C., which is slightly hot to the mouth.

[0142] Comparative Example 1

[0143] Comparative Example 1 is a comparative example of Example 4, except that: no isolation mechanism is provided in the atomizer, and both the functional substance and the atomizer are loaded on the second solid carrier and placed in the first cavity.

[0144] See also Figure 4 :

[0145] (1) Preparation of the second solid carrier 50: the same as step (1) of Example 4.

[0146] (2) Loading the functional substance 30 and the atomizer 40 on the second solid carrier 50: Take 10 g of the porous tea stem particles prepared in step (1) and place them in a mixer. While stirring, spray 1 g of a hot ethanol solution containing 1% ketotifen on the porous tea stem particles in batches. Continue stirring in the mixer at 50°C for half an hour to remove the ethanol. Then, while stirring at 60°C, spray 10 g of glycerol on the porous tea stem particles in batches to prepare a second solid carrier 50 loaded with the functional substance 30 and the atomizer 40 (the loading amount of ketotifen is about 0.05%, and the loading amount of the glycerol atomizer is about 50%).

[0147] (3) Preparing and applying an atomized product: providing an atomizer 10, the atomizer 10 comprising a first cavity 120, a filter mechanism 150 being disposed at one end of the first cavity 120, and an air inlet 140 being disposed on the filter mechanism 150. Adding the second solid carrier 50 loaded with the functional substance 30 and the atomizer 40 prepared in step (2) into the first cavity 120 of the atomizer 10, heating the first cavity 120 by an external heat source so that the glycerin in the second solid carrier 50 loaded with the functional substance 30 and the atomizer 40 reaches an atomization temperature to form an atomizer aerosol, inhaling air from the air inlet 140, the atomizer aerosol is sucked out, during the aspiration process, the atomizer aerosol contacts the functional substance 30, so that ketotifen is dissociated from the second solid carrier 50, and ketotifen is carried out to form an aerosol carrying the functional substance, and the aerosol carrying the functional substance is discharged from the air inlet 140.

[0148] After 23 consecutive puffs of simulated suction by the suction machine (parameters set as: flow rate 18.3 mL / s, simulated inhalation for 3 seconds, and then simulated exhalation for 5 seconds), no functional substance 30 was released. After analysis, the collected aerosol contained a total of 2.8 mg of ketotifen, and the total release rate of ketotifen was 28%. It can be seen that in the process of atomizing the atomizer 40 into aerosol, the functional substance 30 was also directly heated at high temperature, causing the functional substance 30 to deteriorate, greatly reducing the release rate of the functional substance 30.

[0149] According to the test of infrared temperature measuring instrument, the highest temperature of aerosol passing through the filter mechanism 220 to the air inlet 230 is 47°C, and the artificial inhalation test obviously burns the mouth.

[0150] Comparative Example 2

[0151] Comparative Example 1 is a comparative example of Example 4, except that: no isolation mechanism is provided in the atomizer, and the first solid carrier loaded with the functional substance and the second solid carrier loaded with the atomizer are both placed in the first cavity.

[0152] See also Figure 5 :

[0153] (1) Preparation of the first solid carrier 20 and the second solid carrier 50: the same as step (1) of Example 4.

[0154] (2) Loading the functional substance 30 on the first solid carrier 20: the same as step (2) of Example 4.

[0155] (3) Loading the atomizer 40 onto the second solid carrier 50: the same as step (3) of Example 4.

[0156] (4) Preparing and applying the atomized product: providing an atomizer 10 , the atomizer 10 comprising a first cavity 120 , a filter mechanism 150 being disposed at one end of the first cavity 120 , and an air inlet 140 being disposed on the filter mechanism 150 . The second solid carrier 50 loaded with the atomizer 40 prepared in step (3) is added into the first cavity 120 of the atomizer 10, and 0.1 g of the first solid carrier 20 loaded with the functional substance 30 prepared in step (2) is added into the first cavity 120 of the atomizer 10. The first cavity 120 is heated by an external heat source so that the glycerol in the second solid carrier 50 loaded with the atomizer 40 reaches an atomization temperature to form an atomizer aerosol. Inhalation is performed from the air inlet 140, and the atomizer aerosol is sucked out. During the aspiration process, the atomizer aerosol contacts the first solid carrier 20 loaded with the functional substance 30, so that ketotifen and sweet orange essential oil are dissociated from the first solid carrier 20, and ketotifen and sweet orange essential oil are carried out to form an aerosol carrying the functional substance. The aerosol carrying the functional substance is discharged from the air inlet 140.

[0157] Through the simulated suction of suction machine (parameter setting is: flow rate 18.3mL / s, continuous 3s simulated suction, simulated exhalation 5s afterwards), after continuous suction 20 times, no functional substance 30 is released.After analysis, the ketotifen of 0.041mg is contained in the collected aerosol, and the total release rate of ketotifen is 41%.It can be seen that in the process that atomizer 40 is atomized into aerosol, high temperature heating is directly carried out to functional substance 30, part of functional substance 30 can be deteriorated, thereby the release rate of functional substance 30 is reduced, but, because functional substance 30 is loaded on the first solid carrier 20, not directly loaded on the second solid carrier 50, the first solid carrier 20 has certain fluidity in the first cavity 120, relative to comparative example 1, the degree of deterioration of functional substance 30 affected by high temperature is weakened, so the release rate is slightly higher than comparative example 1.But in general, because functional substance 30 still has the risk of high temperature deterioration, the release stability of functional substance 30 is significantly affected.

[0158] According to the test of infrared temperature measuring instrument, the highest temperature of aerosol passing through the filter mechanism 220 to the air inlet 230 is 53°C, and the artificial inhalation test obviously burns the mouth.

[0159] Comparative Example 3

[0160] Comparative Example 3 is a comparative example of Example 5, except that: the second solid carrier loaded with the atomizer is added into the first cavity, and the first solid carrier loaded with the functional substance is not added into the second cavity.

[0161] See also Figure 6 :

[0162] (1) Preparation of the second solid carrier 50: the same as step (1) of Example 5.

[0163] (2) Loading the atomizer 40 onto the second solid carrier 50: the same as step (3) of Example 5.

[0164] (4) Preparing and applying an atomized product: providing an atomizer 10, the atomizer 10 comprising a first cavity 120 and a second cavity 130 separated by an isolation mechanism 110, the second cavity 130 being provided with a filter mechanism 150 in a direction away from the isolation mechanism 110, and an air inlet 140 being provided on the filter mechanism 150. Adding the second solid carrier 50 loaded with the atomizer 40 prepared in step (3) into the first cavity 120 of the atomizer 10, heating the first cavity 120 by an external heat source, so that the atomizer 40 in the second solid carrier 50 reaches an atomization temperature to form an atomizer aerosol, inhaling air from the air inlet 140, and the atomizer aerosol is discharged from the air inlet 140.

[0165] According to the test of infrared temperature measuring instrument, the highest temperature of aerosol passing through the filter mechanism 150 to the air inlet 140 is 51°C, and the artificial inhalation test obviously burns the mouth.

[0166] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0167] The above-mentioned embodiments only express several implementation methods of the present invention, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of this application. Therefore, the protection scope of the patent of this application shall be subject to the attached claims.

Claims

1. An atomization product, characterized in that: include: Nebulizers, functional substances and nebulizers; The atomizer can generate an atomizer aerosol after atomization; The atomizer comprises a first cavity and a second cavity separated by an isolation mechanism, the atomizer is loaded in the first cavity, the functional substance is loaded in the second cavity, and the isolation mechanism confines the atomizer in the first cavity; The second cavity is also provided with an air inlet, and the aerosol of the atomizer passes through the isolation mechanism from the first cavity into the second cavity and contacts with the functional substance to form an aerosol carrying the functional substance, and the aerosol carrying the functional substance is discharged from the air inlet.

2. The atomization product according to claim 1, characterized in that: The atomizer includes an inert liquid that can be atomized to form an aerosol; Optionally, the atomization temperature of the atomizer is ≤250°C; Optionally, the atomizer includes one or more of water, propylene glycol, glycerin, limonene and glyceride substances; Further optionally, the glyceride substance includes one or more of triacetin and caprylic decanoic acid glyceride.

3. The atomization product according to claim 1, characterized in that: The functional substance includes at least one of a substance having biological activity and a substance having sensory properties; Optionally, the biologically active substance includes one or more of ketotifen, rimantadine and nicotine; Optionally, the substance with organoleptic properties includes one or more of essences, essential oils, cooling agents and sweeteners.

4. The atomization product according to any one of claims 1 to 3, characterized in that: The second cavity is also loaded with a first solid carrier, and the functional substance is loaded on the first solid carrier; Optionally, the loading amount of the functional substance is ≥ 0.05%.

5. The atomization product according to claim 4, characterized in that: The first cavity is also loaded with a second solid carrier, and the atomizer is loaded on the second solid carrier; Optionally, the loading amount of the aerosol agent is ≥20%.

6. The atomization product according to claim 5, characterized in that: The first solid support and the second solid support are each independently selected from a porous material having physical adsorption capacity; Optionally, the water content of the porous material having physical adsorption capacity is ≤8%; Optionally, the chemical composition of the porous material having physical adsorption capacity includes one or more of starch and cellulose; Further optionally, the cellulose includes one or more of natural plant cellulose, microcrystalline cellulose, methyl cellulose and hydroxypropyl methyl cellulose.

7. The atomization product according to claim 6, characterized in that: The method of loading the functional substance on the first solid carrier comprises the following steps: spraying a liquid containing the functional substance on the first solid carrier; The method of loading the atomizer on the second solid carrier comprises the following steps: spraying the liquid containing the atomizer on the second solid carrier.

8. The atomization product according to any one of claims 5 to 7, characterized in that: The isolation mechanism has at least one air permeable hole, and the diameter of the air permeable hole is smaller than the diameters of the first solid carrier and the second solid carrier.

9. The atomization product according to any one of claims 1 to 3 and 5 to 7, characterized in that: During the process in which the atomizer aerosol contacts the functional substance to form the aerosol carrying the functional substance, the temperature of the atomizer aerosol is ≤150°C.

10. The atomization product according to any one of claims 1 to 3 and 5 to 7, characterized in that: The temperature of the aerosol carrying the functional substance discharged from the air inlet is ≤40°C.

11. A method for applying the atomized product according to any one of claims 1 to 10, characterized in that: The steps include: Atomizing the atomizer to generate the atomizer aerosol; Inhalation is performed through the inhalation port, and the atomizer aerosol passes through the isolation mechanism from the first cavity into the second cavity and contacts with the functional substance to form an aerosol carrying the functional substance, and the aerosol carrying the functional substance is discharged from the inhalation port.

12. Use of the atomized product according to any one of claims 1 to 10 in the field of medical products or in the field of tobacco.

13. A method for preparing a porous material with physical adsorption capacity, characterized in that: The method comprises the following steps: mixing the chemical components of the porous material with physical adsorption capacity with water, granulating the mixture and drying the mixture.

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