Traditional Chinese medicine composition for treating chronic prostatitis and preparation method and application thereof

By using traditional Chinese medicine compositions of pony lotus, corn squirrel, autumn sorghum, mutong, Morinica, Angelica, Kumbu and Mutus, the problem of unsatisfactory treatment of chronic prostatitis and prone to recurrence was solved, and significant Clinical efficacy and low recurrence rates provide an affordable and safe treatment option.

CN119258177APending Publication Date: 2025-01-07马成
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Patent Information

Application Number
CN202411691139.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-25
Publication Date
2025-01-07

AI Technical Summary

Technical Problem

The existing methods for treating chronic prostatitis are not effective, especially in the long-term efficacy and are prone to recurrence. There are insufficient specificity of Western medical methods, and traditional Chinese medicine methods are cumbersome and have poor results.

Method used

Provided a traditional Chinese medicine composition, including pony lotus, corn squid, autumn sorghum, mutong, Morindae, Angelica sinensis, Kermbu and Mutus seeds, prepared by soaking and decocting in water, and has the ability to clear heat and diuresis, promote blood circulation and remove blood stasis and soften hardness. The effect of dispersing the nodules is used to treat chronic prostatitis.

Benefits of technology

This traditional Chinese medicine composition significantly improves inflammation symptoms in clinical applications, with a cure rate of more than 67%, a total effective rate of more than 93%, and few or no recurrence cases within 6 months. It has the characteristics of accurate efficacy, economical and small side effects. .

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Abstract

The invention provides a traditional Chinese medicine composition for treating chronic prostatitis and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 3-6 parts of herba lepidogrammitis, 2-5 parts of corn stigma, 4-8 parts of autumn sorghum, 1-2 parts of caulis akebiae, 1-2 parts of radix morindae officinalis, 1-2 parts of radix angelicae sinensis, 1-2 parts of kelp and 1-2 parts of semen momordicae. The traditional Chinese medicine composition is reasonable in formula compatibility, has the effects of eliminating dampness and heat, promoting blood circulation to remove blood stasis and softening hardness to dissipate stagnation, has a remarkable effect on clinical treatment of chronic prostatitis, and is free of residues and not prone to relapse.
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Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating chronic prostatitis, and a preparation method and application thereof. Background Art

[0002] Chronic prostatitis (CP) is a syndrome characterized by pain (in the lower abdomen, lumbosacral region, medial thigh, perineum, scrotum, etc.), abnormal urination (dysuria, frequent urination, urgency, burning or itching sensation in the urethra, residual urine, white dripping from the urethral orifice), and psychoneurological symptoms (insomnia, dreaminess, dizziness, tinnitus, tension, anxiety, etc.), or sexual dysfunction such as premature ejaculation and impotence. There is widespread controversy in the study of etiology and pathogenesis in Western medicine. The main purpose of treatment is to relieve symptoms, which lacks specificity. Its methods mainly include oral treatment with Western medicine antibiotics, nonsteroidal anti-inflammatory analgesics, biofeedback therapy, physical therapy, prostate massage, and surgery, but the efficacy is general, especially the long-term efficacy is not ideal. Traditional Chinese medicine is a huge treasure trove. It has obvious advantages in the treatment of CP, such as a profound theoretical basis, diverse treatment methods, good clinical efficacy, and fewer toxic and side effects. However, some methods are cumbersome, difficult to operate, and have poor effects, and are prone to recurrence. Summary of the invention

[0003] In view of this, the object of the present invention is to provide a Chinese medicine composition for treating chronic prostatitis, which has the characteristics of significant efficacy, low recurrence and no toxic side effects.

[0004] The invention provides a traditional Chinese medicine composition, comprising the following raw materials in parts by weight: 3-6 parts of smilax china, 2-5 parts of corn silk, 4-8 parts of autumn sorghum, 1-2 parts of akebia, 1-2 parts of morinda officinalis, 1-2 parts of angelica sinensis, 1-2 parts of kelp and 1-2 parts of momordica seeds.

[0005] Preferably, the following raw materials are included in parts by weight:

[0006] 4-6 parts of small Ma Lian, 3-4 parts of corn silk, 5-7 parts of autumn sorghum, 1.5-2 parts of Akebia, 1.5-2 parts of Morinda officinalis, 1.5-2 parts of Angelica sinensis, 1.5-2 parts of Kelp and 1.5-2 parts of Momordica cochinchinensis.

[0007] Preferably, the following raw materials are included in parts by weight:

[0008] 6 parts of Malianthus fragrans, 3 parts of Corn Silk, 6 parts of Autumn Sorghum, 2 parts of Akebia, 2 parts of Morinda Officinalis, 2 parts of Angelica Sinensis, 2 parts of Kelp and 2 parts of Momordica charantia.

[0009] The present invention provides a method for preparing the Chinese medicine composition, comprising the following steps:

[0010] The raw materials of smilax china, corn silk, autumn sorghum, akebia, morinda officinalis, angelica sinensis, kelp and momordica charantia are soaked in water, then boiled and the boiling liquid is separated.

[0011] Preferably, the volume ratio of the total mass of the raw materials to water is 70-145 g:600 ml.

[0012] Preferably, the decocting time is 30 to 40 minutes.

[0013] Preferably, after the decoction is completed and the decoction liquid is separated, the remaining medicinal residue is decocted again with water for 2 to 3 times, the second decoction liquid is separated, and the decoction liquid is combined with the decoction liquid to obtain a traditional Chinese medicine composition.

[0014] Preferably, the mass volume ratio of the medicinal residue to water is 70-145 g:300 ml;

[0015] The time for the second decoction is 30 to 40 minutes.

[0016] The present invention provides application of the Chinese medicine composition or the Chinese medicine composition prepared by the preparation method in preparing medicine for treating chronic prostatitis.

[0017] Preferably, the dosage form of the drug includes at least one of the following: decoction, pills, pills and granules.

[0018] The present invention provides a Chinese medicine composition, comprising the following raw materials in parts by weight: 3-6 parts of small horsetail, 2-5 parts of corn silk, 4-8 parts of autumn sorghum, 1-2 parts of akebia, 1-2 parts of Morinda officinalis, 1-2 parts of angelica, 1-2 parts of kelp and 1-2 parts of Momordica. The Chinese medicine composition provided by the present invention has the effects of clearing away heat and promoting diuresis, promoting blood circulation and removing blood stasis, and softening and dispersing nodules, and has a significant effect in treating chronic prostatitis, no adverse reactions are found, and it is not easy to relapse. The results of the embodiment of the present invention show that the Chinese medicine composition decoction prepared by the present invention is taken by the confirmed chronic prostatitis patients, and the treatment is 1 month. According to clinical observation, the cure rate reaches more than 67%, the total effective rate is more than 93%, and there are fewer or no recurrence cases within 6 months, and the clinical treatment effect is better than that of other Chinese medicine compositions. It can be seen that the Chinese medicine composition provided by the present invention has the characteristics of definite efficacy, economical and practical, small side effects, and not easy to relapse, which provides a new means for the clinical treatment of prostatitis patients. DETAILED DESCRIPTION

[0019] The invention provides a traditional Chinese medicine composition, comprising the following raw materials in parts by weight: 3-6 parts of smilax china, 2-5 parts of corn silk, 4-8 parts of autumn sorghum, 1-2 parts of akebia, 1-2 parts of morinda officinalis, 1-2 parts of angelica sinensis, 1-2 parts of kelp and 1-2 parts of momordica seeds.

[0020] The raw materials of the Chinese medicine composition provided by the present invention include small horsetail. By weight, the small horsetail is preferably 4 to 6 parts, and can be 5 parts or 6 parts. The small horsetail is the whole herb of the Asteraceae plant horsetail, which is bitter, cold in nature, and enters the heart and liver meridians. It has the effect of clearing away heat and detoxifying, and can be used clinically to treat colds and fever, sore throat, heat toxic bloody diarrhea, carbuncle swelling and sore; it also has the effect of cooling blood and stopping bleeding, and can be used clinically to treat bloody stools, metrorrhagia, hematuria, epistaxis and other diseases. It has the effect of promoting urination and relieving urination discomfort. In the present invention, chronic prostatitis is caused by damp-heat toxic evil accumulated in the genitals, and the small horsetail plays a role in clearing heat and promoting diuresis and promoting urination.

[0021] The raw materials of the Chinese medicine composition provided by the present invention include corn silk. The corn silk is preferably 3 to 4 parts by weight. The corn silk is the style and stigma of the plant of Zea mays of the Gramineae family, and has the effects of promoting diuresis and reducing swelling, promoting dampness and reducing jaundice. It is mainly used to treat edema and jaundice. Corn silk and autumn high grain enhance the effect of clearing heat and promoting diuresis, make up for the lack of the effect of Xiaoma lotus seeds in clearing heat and promoting diuresis, and have the effects of food therapy and supporting positive energy.

[0022] The raw materials of the Chinese medicine composition provided by the present invention include autumn sorghum. In terms of weight, the autumn sorghum is preferably 5 to 7 parts, and can be 6 parts. The autumn sorghum belongs to the annual herb of the genus Sorghum of the Gramineae family and is one of the cereal crops. There are many types of sorghum, which can be divided into white sorghum, red sorghum, yellow sorghum, etc. according to the appearance and color of the sorghum ear. Sorghum likes warmth and light, is sweet in taste and warm in nature, and has the effects of stopping diarrhea, lowering blood sugar, strengthening the spleen and stomach, and promoting digestion.

[0023] The raw materials of the Chinese medicine composition provided by the present invention include Akebia. The Akebia preferably includes 1.5 to 2 parts by weight. The Akebia has the effects of clearing away heat and promoting diuresis, removing dampness and reducing swelling, detoxifying, relieving pain, and promoting menstruation and lactation, and is mainly used to treat symptoms such as stranguria, edema, phlegm and water vapor, amenorrhea and dysmenorrhea. When using it, it should be noted that it is cold in nature, and long-term and large-scale use can easily damage the yin.

[0024] The raw materials of the Chinese medicine composition provided by the present invention include Morinda officinalis. The Morinda officinalis preferably includes 1.5 to 2 parts by weight. The Morinda officinalis has the effects of nourishing the kidney and strengthening yang, increasing semen volume, regulating endocrine, strengthening tendons and bones, and improving immunity.

[0025] The raw materials of the Chinese medicine composition provided by the present invention include angelica. By weight, the angelica preferably includes 1.5 to 2 parts. The angelica is the root of the perennial herbaceous plant angelica of the Umbelliferae family, which is sweet, pungent, warm in nature, and enters the liver, heart, and spleen meridians. It has the functions of nourishing blood, promoting blood circulation, regulating menstruation and relieving pain, moistening and lubricating the intestines, and is mainly used for various symptoms of blood deficiency, irregular menstruation, amenorrhea, dysmenorrhea, accumulation of masses, metrorrhagia, abdominal pain due to deficiency and cold, paralysis, numbness of the skin, difficulty in defecation due to dry intestines, heaviness after dysentery, carbuncle, ulcer, and injury due to falls, etc. Angelica and Akebia clear away heat and cool blood, promote blood circulation and nourish blood, and heat and toxicity will accumulate, which will cause qi stagnation and blood stasis. The longer the course of the disease, the more severe the mutual binding of evil toxins and blood stasis.

[0026] The raw materials of the Chinese medicine composition provided by the present invention include kelp. The kelp preferably includes 1.5 to 2 parts by weight. The kelp is the dried fronds of Laminaria japonica or Laminaria japonica, which is salty in taste and cold in nature. It enters the liver, stomach and kidney meridians and has the effects of eliminating phlegm, softening and dispersing nodules, promoting diuresis and reducing swelling. It is used for goiter, scrofula, testicular swelling and pain, and edema caused by phlegm and fluid retention.

[0027] The raw materials of the Chinese medicine composition provided by the present invention include Momordica cochinchinensis. According to weight, the Momordica cochinchinensis preferably includes 1.5 to 2 parts. The Momordica cochinchinensis is the dried mature seeds of the Momordica cochinchinensis of the Cucurbitaceae family, and is also known as: wooden crab, earthen turtle, shell turtle, leaking lingzi, ground tung seed, rattan tung seed, Momordica cochinchinensis, bitter, slightly sweet, cool in nature, and enters the liver, spleen, and stomach meridians. It has the effects of dispersing stagnation and reducing swelling, attacking toxins and treating sores, and is effective in treating swelling and hyperplasia of the prostate.

[0028] In the present invention, the Chinese medicine composition is composed of small horsetail, corn silk, autumn sorghum, aketong, Morinda officinalis, angelica, kelp, and cochinchinensis; in the square, small horsetail has the effect of clearing heat and promoting diuresis, and promoting urination; cochinchinensis plays the role of attacking poison and curing sores, dispersing nodules and reducing swelling, and the two have the effect of clearing heat and detoxifying, diuresis and dispersing nodules, and are the main medicine; corn silk and autumn sorghum have the effect of clearing heat and promoting diuresis, combined with the salty and cold effect of kelp, they have the effect of eliminating phlegm, softening and dispersing nodules, and help the main medicine to strengthen the heat-clearing and detoxifying diuresis, and dissipate as the minister; angelica and aketong have the merits of clearing heat and cooling blood, promoting blood circulation and nourishing blood, and diuresis, and promote the excretion of damp heat adjuvant; Morinda officinalis adjuvant replenishes kidney yang, enhances immunity, and strengthens body metabolism. The whole prescription is rigorous, the medicine is specialized and refined, the curative effect is remarkable and fast, the price is low, and it is not easy to relapse, and it has significant promotion value.

[0029] The present invention provides a method for preparing the Chinese medicine composition, comprising the following steps:

[0030] The raw materials of smilax china, corn silk, autumn sorghum, akebia, morinda officinalis, angelica sinensis, kelp and momordica charantia are soaked in water, then boiled and the boiling liquid is separated.

[0031] In the present invention, the volume ratio of the total mass of the raw materials to water is preferably 70-145g:600ml, which can be 21g:120mL. The soaking time is preferably 30-40min, which can be 35min. The decoction time is preferably 30-40min, which can be 35min. After the decoction is completed and the decoction liquid is separated, the remaining medicinal residue is preferably decocted again with water for 2-3 times, the decoction liquid is separated again, and the decoction liquid is combined with the decoction liquid to obtain a traditional Chinese medicine composition. The mass volume ratio of the medicinal residue and water is preferably 70-145g:300ml, which can be 7g:20ml. The time for the second decoction is preferably 30-40min.

[0032] The present invention provides application of the Chinese medicine composition or the Chinese medicine composition prepared by the preparation method in preparing medicine for treating chronic prostatitis.

[0033] In the present invention, the clinical symptoms of chronic prostatitis include abnormal urination (frequent urination, urgent urination, painful urination, dribbling urination, residual urine after urination, burning urethra, short and red urine, etc.), pain symptoms (can be seen in the lower abdomen, perineum, testicles, lumbosacral region or urethra, which can be manifested as burning pain in the urethra during urination, pain during sexual intercourse or pain during ejaculation, etc.), and associated symptoms (urinary tract itching, scrotal moisture, dry mouth and bitter mouth, sexual dysfunction, depression and anxiety, insomnia and forgetfulness, etc. Rectal examination: the prostate is slightly enlarged, not large or slightly smaller, tender, and slightly hard in texture). The auxiliary examination indicators of chronic prostatitis include urinary system color Doppler ultrasound (uneven prostate echo, calcification spots or calcification foci), urine routine (white blood cell count within the normal range) and prostate fluid routine (lecithin bodies are reduced or normal, white blood cell count is increased or normal). The treatment of chronic prostatitis is manifested in improving the inflammatory symptom index, relieving or alleviating pain or discomfort, urination symptoms and improving the quality of life, as well as reducing the number of white blood cells in serum.

[0034] In the present invention, the dosage form of the drug preferably includes at least one of the following: decoction, pill, pill and granule. The present invention has no special restrictions on the preparation method of the drug, and the preparation method of the drug dosage form known in the art can be used. The method of taking the drug is to take it continuously for 10 days, three times a day, and the total mass of the raw material of the drug per day is 105g.

[0035] In one embodiment of the present invention, the cure rate of the treatment group using the Chinese medicine composition provided by the present invention is more than 67%, the total effective rate is more than 93%, and there are no recurrence cases or fewer recurrence cases in 6 months. The total effective rate of the Western medicine control group (tamsulosin hydrochloride sustained-release capsules) is only 80%, and the recurrence rate in 6 months is 43%. At the same time, the total effective rate of the control Chinese medicine composition group is 77% to 90%, the cure rate is only 14% to 40%, and the recurrence rate in 6 months is 13.3% to 26.7%.

[0036] The following is a detailed description of a Chinese medicine composition for treating chronic prostatitis provided by the present invention, as well as its preparation method and application, in conjunction with the embodiments. However, they should not be construed as limiting the scope of protection of the present invention.

[0037] Example 1

[0038] A preparation method of a Chinese medicine composition for treating chronic prostatitis

[0039] 1. Weigh the Chinese medicine according to the following ratio:

[0040] 30g of Malianthus annuus, 15g of corn silk, 30g of autumn sorghum, 10g of Akebia, 10g of Morinda officinalis, 10g of Angelica sinensis, 10g of Kelp and 10g of Momordica charantia.

[0041] 2. Mix the weighed medicines and put them into a medicine pot. First, add 600 ml of water to soak for 30 minutes, boil for 40 minutes, filter out, then add 300 ml of water to the medicine pot and boil for 30 minutes, filter out, and finally add 300 ml of water to the medicine pot and boil for 30 minutes, filter out, combine the three filtrates, and collect the medicine soup.

[0042] 3. Directions for use: Divide the medicine soup into three equal portions, heat it to a suitable temperature each time and take it three times a day for 10 consecutive days.

[0043] Example 2

[0044] A preparation method of a Chinese medicine composition for treating chronic prostatitis

[0045] 1. Weigh the Chinese medicine according to the following ratio:

[0046] 15g of Malianthus annuus, 25g of corn silk, 20g of autumn sorghum, 5g of Akebia, 5g of Morinda officinalis, 5g of Angelica sinensis, 5g of Kelp and 5g of Momordica charantia.

[0047] 2. Mix the weighed medicines and put them into a medicine pot. First, add 600 ml of water to soak for 30 minutes, boil for 40 minutes, filter out, then add 300 ml of water to the medicine pot and boil for 30 minutes, filter out, and finally add 300 ml of water to the medicine pot and boil for 30 minutes, filter out, combine the three filtrates, and collect the medicine soup.

[0048] 3. Directions for use: Divide the medicine soup into three equal portions, heat it to a suitable temperature each time and take it three times a day for 10 consecutive days.

[0049] Example 3

[0050] A preparation method of a Chinese medicine composition for treating chronic prostatitis

[0051] 1. Weigh the Chinese medicine according to the following ratio:

[0052] 25g of Malianthus annuus, 10g of corn silk, 40g of autumn sorghum, 7.5g of Akebia, 7.5g of Morinda officinalis, 7.5g of Angelica sinensis, 7.5g of Kelp and 7.5g of Momordica charantia.

[0053] 2. Mix the weighed medicines and put them into a medicine pot. First, add 600 ml of water to soak for 30 minutes, boil for 40 minutes, filter out, then add 300 ml of water to the medicine pot and boil for 30 minutes, filter out, and finally add 300 ml of water to the medicine pot and boil for 30 minutes, filter out, combine the three filtrates, and collect the medicine soup.

[0054] 3. Directions for use: Divide the medicine soup into three equal portions, heat it to a suitable temperature each time and take it three times a day for 10 consecutive days.

[0055] Comparative Example 1

[0056] A preparation method of a Chinese medicine composition for treating chronic prostatitis

[0057] On the basis of Example 1, the addition of Momordica cochinchinensis was omitted. The preparation method thereof was the same as that of Example 1.

[0058] Comparative Example 2

[0059] A preparation method of a Chinese medicine composition for treating chronic prostatitis

[0060] On the basis of Example 1, the addition of kelp was omitted. The preparation method was the same as that of Example 1.

[0061] Comparative Example 3

[0062] A preparation method of a Chinese medicine composition for treating chronic prostatitis

[0063] On the basis of Example 1, the addition of autumn sorghum is omitted. The preparation method is the same as that of Example 1.

[0064] Comparative Example 4

[0065] A preparation method of a Chinese medicine composition for treating chronic prostatitis

[0066] On the basis of Example 1, the addition of Herba Lysimachiae was omitted. The preparation method thereof is the same as that of Example 1.

[0067] Comparative Example 5

[0068] A preparation method of a Chinese medicine composition for treating chronic prostatitis

[0069] On the basis of Example 1, the addition of Morinda officinalis and Angelica sinensis was omitted. The preparation method thereof is the same as that of Example 1.

[0070] Comparative Example 6

[0071] A preparation method of a Chinese medicine composition for treating chronic prostatitis

[0072] On the basis of Example 1, the two herbs of small lotus and autumn sorghum are replaced by plantain and shiwei. The preparation method is the same as that of Example 1.

[0073] Example 4

[0074] Clinical trial results

[0075] 1. Clinical data

[0076] 1.1 General Information

[0077] A total of 210 patients with flat warts who visited the outpatient clinic of Huixian People's Hospital from January 2018 to June 2024, aged 16 to 76 years, were selected and divided into 7 groups by random number method according to the needs of clinical research, with 30 patients in each group.

[0078] 1.2 Diagnostic criteria

[0079] Western medicine diagnostic criteria: The diagnostic criteria for CP were formulated with reference to the 2014 edition of the "Guidelines for Diagnosis and Treatment of Urological Diseases in China".

[0080] Clinical symptoms: ① Abnormal urination: frequent urination, urgent urination, painful urination, dribbling urination, residual urination, burning sensation in the urethra, short and dark urine, etc.;

[0081] ② Pain symptoms: can be seen in the lower abdomen, perineum, testicles, lumbar sacral region or urethra, which can manifest as burning pain in the urethra during urination, pain during sexual intercourse or pain during ejaculation;

[0082] ③ Associated symptoms: urethral itching, scrotal moisture, dry mouth and bitter taste, sexual dysfunction, depression and anxiety, insomnia and forgetfulness, etc. Rectal examination: The prostate is slightly enlarged, not large or slightly smaller, tender, and slightly hard.

[0083] Auxiliary examinations: ①Urinary system color Doppler ultrasound: uneven echo of the prostate, with calcification spots or calcification foci;

[0084] ② Urinalysis: white blood cell count is within the normal range;

[0085] ③ Routine examination of prostatic fluid: decreased or normal lecithin bodies, increased or normal white blood cell count.

[0086] Symptom indicators and laboratory indicators were evaluated before treatment and one month after treatment. Symptom indicators were evaluated according to the Chronic Prostatitis Symptom Index (NIH-CPSI), including pain or discomfort, urination symptoms, and quality of life. Laboratory indicators selected the white blood cell count in prostatic fluid, and the white blood cell count was measured in prostatic fluid before treatment and one month after treatment.

[0087] 1.3 Treatment methods

[0088] The first to sixth groups were orally administered the pharmaceutical preparations and administration methods prepared in Examples 1 to 3 and Comparative Examples 1 to 5. The seventh group was set as the control group and treated with conventional tamsulosin hydrochloride sustained-release capsules (Astellas Co., Ltd., National Medicine Standard No.: H20000681). One capsule was taken orally every night for 4 consecutive weeks.

[0089] 1.4 Criteria for determining efficacy

[0090] ① Clinical efficacy criteria: Referring to the diagnostic criteria, clinical cure: NIH-CPSI score reduction ≥ 90%; marked effect: NIH-CPSI score reduction 70% to 89%; effective: NIH-CPSI score reduction 35% to 69%; ineffective: NIH-CPSI score reduction <35% or no change.

[0091] ② TCM syndrome efficacy standard: According to the "Guidelines for Clinical Research of New Chinese Medicines (Trial)" and "Expert Consensus on the Diagnosis and Treatment of Chronic Prostatitis with Integrated Chinese and Western Medicine", cure: symptom improvement rate ≥ 95%; marked effect: symptom improvement rate < 95% and ≥ 60%; effective: symptom improvement rate < 60% and ≥ 30%; ineffective: symptom improvement rate < 30%. Calculate the symptom improvement rate according to formula I:

[0092] Symptom improvement rate (%) = (total score before treatment - total score after treatment) / total score before treatment × 100% Formula I.

[0093] 2. Treatment Effect

[0094] After taking the present invention for treatment for 1 month, clinical observation showed that Example 1 had outstanding efficacy, and follow-up statistics showed no obvious discomfort and side effects, as shown in Table 1.

[0095] Table 1 Follow-up statistical results of treatment effect

[0096]

[0097] It can be seen from the statistical results in Table 1 that the prescription of Example 1 is the most reasonable, has the effects of clearing away dampness and heat, promoting blood circulation and removing blood stasis, and softening and dispersing nodules, and has a significant effect in treating chronic prostatitis, has no residue and is not prone to recurrence.

[0098] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A Chinese medicine composition for treating chronic prostatitis, characterized in that: The invention comprises the following raw materials in parts by weight: 3-6 parts of small Ma Lian, 2-5 parts of corn silk, 4-8 parts of autumn sorghum, 1-2 parts of Akebia, 1-2 parts of Morinda officinalis, 1-2 parts of Angelica sinensis, 1-2 parts of Kelp and 1-2 parts of Momordica cochinchinensis.

2. The Chinese medicine composition according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 4-6 parts of small Ma Lian, 3-4 parts of corn silk, 5-7 parts of autumn sorghum, 1.5-2 parts of Akebia, 1.5-2 parts of Morinda officinalis, 1.5-2 parts of Angelica sinensis, 1.5-2 parts of Kelp and 1.5-2 parts of Momordica cochinchinensis.

3. The Chinese medicine composition according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 6 parts of Malianthus fragrans, 3 parts of Corn Silk, 6 parts of Autumn Sorghum, 2 parts of Akebia, 2 parts of Morinda Officinalis, 2 parts of Angelica Sinensis, 2 parts of Kelp and 2 parts of Momordica charantia.

4. A method for preparing the Chinese medicine composition according to any one of claims 1 to 3, characterized in that: The following steps are involved: The raw materials of smilax china, corn silk, autumn sorghum, akebia, morinda officinalis, angelica sinensis, kelp and momordica charantia are soaked in water, then boiled and the boiling liquid is separated.

5. The preparation method according to claim 4, characterized in that: The volume ratio of the total mass of the raw materials to water is 70-145 g:600 ml.

6. The preparation method according to claim 4, characterized in that: The decoction time is 30 to 40 minutes.

7. The preparation method according to any one of claims 4 to 6, characterized in that: After the decoction is completed and the decoction liquid is separated, the remaining medicinal residue is decocted again with water for 2 to 3 times, the second decoction liquid is separated, and the decoction liquid is combined with the decoction liquid to obtain a traditional Chinese medicine composition.

8. The preparation method according to claim 7, characterized in that: The mass volume ratio of the medicinal residue to water is 70-145 g:300 ml; The time for the second decoction is 30 to 40 minutes.

9. Use of the Chinese medicine composition according to any one of claims 1 to 3 or the Chinese medicine composition prepared by the preparation method according to any one of claims 4 to 8 in the preparation of a medicament for treating chronic prostatitis.

10. The use according to claim 9, characterized in that: The dosage form of the drug includes at least one of the following: decoction, pills, pills and granules.