Composition with mosquito repelling, soothing and after-sun repairing effects

Abstract

The invention relates to the technical field of mosquito repellent, soothing and after-sun repair compositions, and in particular to a composition capable of repelling mosquitoes, soothing and after-sun repairing effects. The composition comprises the following components by weight: 75.0-90.0 parts of water; 3.0-7.0 parts of methyl propanediol; 3.0-7.0 parts of olea europaea seed oil; 2.0-6.0 parts of menthol; 0.3-0.7 parts of sorbitan olivate; 0.3-0.7 parts of cetearyl glucoside; 0.3-0.7 parts of 1,2-hexanediol; 0.3-0.7 parts of citronella oil; 0.2-0.6 parts of phenoxyethanol; 0.03-0.07 parts of caper fruit extract; 0.02-0.05 parts of chrysanthemum cactus stem extract; and 0.03-0.06 parts of olive leaf extract. The fatty acids in the olea europaea seed oil not only have excellent mosquito repellent effects, but also can strengthen skin barrier functions.

Description

Technical Field

[0001] The invention relates to the technical field of mosquito repelling, soothing and after-sun repairing compositions, and in particular to a composition having mosquito repelling, soothing and after-sun repairing effects. Background Art

[0002] As people's enthusiasm for outdoor activities and exploring nature grows, the demand for multifunctional outdoor care products that can fully protect the skin is also increasing. However, existing outdoor care products often have problems such as single efficacy, inconvenience in use, or potential harm to the skin and the environment.

[0003] Currently, common mosquito repellent products on the market mainly rely on chemically synthesized mosquito repellents, such as DEET (N,N-diethyl-3-methylbenzamide). Although such products have a strong mosquito repellent effect, long-term use may cause skin irritation and even pose potential risks to human health. In addition, these chemical mosquito repellents often lack other skin care effects and cannot meet users' needs for comprehensive skin protection during outdoor activities.

[0004] On the other hand, although some natural plant essential oil-based mosquito repellent products are relatively safe, their mosquito repellent effect and durability are often not as good as chemical mosquito repellents. At the same time, such products usually lack additional functions such as soothing and repairing, and are difficult to cope with the multiple damages caused to the skin by the complex outdoor environment.

[0005] In the field of after-sun repair, most existing products focus on moisturizing and soothing, but few can provide effective mosquito repellent protection at the same time. This means that users need to carry a variety of products with different functions during outdoor activities, which is not convenient to use.

[0006] Based on the above situation, developing a product that integrates multiple functions of mosquito repellent, soothing and after-sun repair has become a technical problem that needs to be solved urgently. Summary of the invention

[0007] The present invention aims to solve the following technical problems. The present invention provides a composition with mosquito repelling, soothing and after-sun repairing effects. This product not only needs to have strong and lasting mosquito repelling ability, but also should be able to effectively soothe and repair damaged skin while ensuring safety to the human body and the environment.

[0008] The object of the present invention is to provide a composition having mosquito repelling, soothing and after-sun repairing effects, wherein the composition comprises the following components by weight:

[0009] Water 75.0-90.0 parts;

[0010] 3.0-7.0 parts of methyl propylene glycol;

[0011] 3.0-7.0 parts of oleifera seed oil;

[0012] Menthol 2.0-6.0 parts;

[0013] Sorbitan olivate 0.3-0.7 parts;

[0014] Cetearyl glucoside 0.3-0.7 parts;

[0015] 1,2-hexanediol 0.3-0.7 parts;

[0016] Citronella oil 0.3-0.7 parts;

[0017] Phenoxyethanol 0.2-0.6 parts;

[0018] 0.03-0.07 parts of Capparis spinosa fruit extract;

[0019] 0.02-0.05 parts of Xiantao cactus stem extract;

[0020] Olive leaf extract 0.03-0.06 parts;

[0021] Maltodextrin 0.08-0.15 parts;

[0022] Trehalose 0.08-0.12 parts;

[0023] Carbomer 0.08-0.12 parts;

[0024] 0.08-0.12 parts of triethanolamine;

[0025] Ethylhexylglycerin 0.08-0.12 parts.

[0026] Preferably, the calendula seed oil has the following characteristics:

[0027] Appearance: light yellow to yellowish brown oily liquid;

[0028] Density at 25°C: 0.90-0.93 g / cm³;

[0029] The refractive index at 25°C is 1.460-1.470;

[0030] Acid value ≤5.0 mg KOH / g;

[0031] The iodine value is 60-75 g I2 / 100g.

[0032] Preferably, the citronella oil has the following characteristics:

[0033] Appearance: light yellow to yellow transparent liquid;

[0034] Relative density at 20°C is 0.880-0.900;

[0035] The refractive index at 20°C is 1.470-1.490;

[0036] The optical rotation is -5° to +2°;

[0037] Citral content ≥75%.

[0038] Preferably, the total flavonoids content of the Capparis spinosa fruit extract is ≥5% in terms of rutin; the total polysaccharide content of the Opuntia fasciata stem extract is ≥30%; and the total phenol content of the olive leaf extract is ≥15% in terms of hydroxytyrosol.

[0039] Preferably, the preparation method of the composition comprises the following steps:

[0040] Step (1), preparing an oil phase: mixing balsam pear seed oil, citronella oil, sorbitan olivate and cetearyl glucoside, and stirring at 40-50° C. and 200-300 rpm for 15-20 minutes;

[0041] Step (2), preparing an aqueous phase: mixing half of the purified water with carbomer, stirring at 300-400 rpm for 10-15 minutes at room temperature, then adding methylpropanediol, 1,2-hexanediol and trehalose, and continuing stirring for 5-10 minutes;

[0042] Step (3), emulsification: slowly adding the oil phase into the water phase at 40-50° C., stirring at a speed of 400-600 rpm for 15-20 minutes;

[0043] Step (4), adding active ingredients: at 45-55° C., add menthol, caper fruit extract, opuntia cactus stem extract and olive leaf extract in sequence, stirring for 2-3 minutes after each addition of an ingredient, then add the remaining purified water and stir for 5-10 minutes;

[0044] Step (5), pH adjustment and preservation: at 35-40°C, add triethanolamine to adjust the pH to 6.5-7.5, then add phenoxyethanol and ethylhexylglycerin, and stir for 5-10 minutes;

[0045] Step (6), homogenization and cooling: use a high shear homogenizer to homogenize at 5000-8000 rpm for 10-15 minutes, and then slowly cool to room temperature while maintaining low speed stirring at 100-200 rpm.

[0046] Preferably, in step (1), the preparation temperature of the oil phase is 45-48°C, the stirring speed is 250-280 rpm, and the stirring time is 17-18 minutes.

[0047] Preferably, in step (2), the preparation of the aqueous phase is carried out at 22-24° C., the dispersion stirring speed of the carbomer is 350-380 rpm, and the stirring time is 12 to 13 minutes.

[0048] Preferably, in step (3), the temperature of the emulsification process is 46-48°C, the stirring speed is 500-550 rpm, and the stirring time is 17-18 minutes.

[0049] Preferably, in step (4), the adding temperature of the active ingredient is 48-52° C., and the stirring time of each active ingredient is 2.5-3 minutes.

[0050] Preferably, in step (6), the rotation speed of the homogenization process is 6500-7500 rpm, the homogenization time is 12-13 minutes, and the stirring speed during the cooling process is 150-180 rpm.

[0051] The present invention discloses a composition having mosquito repelling, soothing and sun-repairing effects, which has the following innovative features and beneficial effects:

[0052] The present invention successfully combines mosquito repellent, soothing and repairing functions through a carefully designed combination of natural plant extracts. Among them, the synergistic effect of oleoresin seed oil and citronella oil is one of the core innovations of the present invention. The fatty acids in oleoresin seed oil not only have excellent mosquito repellent effects, but also strengthen the skin barrier function. The citral in citronella oil further enhances the mosquito repellent effect while providing a fresh aroma. This unique combination not only surpasses the performance of a single ingredient in mosquito repellent effects, but also unexpectedly exhibits excellent anti-inflammatory and antioxidant capabilities.

[0053] Furthermore, the present invention introduces a variety of plant extracts, such as Capparis spinosa fruit extract, Opuntia ficus-indica stem extract and olive leaf extract. These extracts are rich in polyphenolic compounds, which can effectively inhibit the release of inflammatory factors, thereby achieving a soothing effect. At the same time, they also have strong antioxidant activity, which can neutralize free radicals and protect the skin from oxidative damage. This combination of multiple plant extracts not only provides comprehensive skin protection, but also enhances the overall effect through synergistic effects.

[0054] At the molecular level, the components of the present invention form a complex and efficient synergistic network. For example, the long-chain fatty acids in the oleifera seed oil may interact with the lipid layer on the surface of the skin to form a sustained-release system that continuously releases mosquito repellent ingredients. At the same time, this lipid layer can also serve as a carrier to help other active ingredients such as polyphenols better penetrate into the deep layers of the skin. This unique intermolecular interaction may be the key to the long-lasting mosquito repellent and deep repair effects of the present invention.

[0055] The present invention also cleverly utilizes molecular orbital theory to optimize the stability and bioavailability of the overall formula by adjusting the electronic structure of each component. For example, the unsaturated compounds in citronella oil may enhance the intermolecular forces of the entire system through π-π interactions, thereby improving the durability of the product.

[0056] In addition, the formula of the present invention also takes into account the interaction at the atomic scale. By precisely controlling the atomic ratio of each component, the optimal spatial configuration is achieved, ensuring that the active ingredients can fully exert their effects while minimizing potential adverse reactions.

[0057] In general, the present invention has successfully developed a multifunctional, efficient and safe outdoor skin care product by deeply understanding and utilizing complex chemical mechanisms. It not only solves the problems of single efficacy and inconvenience in use in the prior art, but also achieves synergistic enhancement of multiple efficacy through unique formula design. This innovative technical solution provides a comprehensive and convenient skin protection solution for outdoor activity enthusiasts, which has important practical value and broad market prospects. DETAILED DESCRIPTION

[0058] In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be clearly and completely described below in conjunction with the specific embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0059] The use of olea europaea seed oil as the main mosquito repellent ingredient is an important innovation of the present invention. Olea europaea seed oil originates from the Amazon region and has a natural mosquito repellent effect. The selection of this natural ingredient rather than synthetic chemical mosquito repellents not only ensures the effectiveness of the product, but also improves safety and environmental friendliness. The addition of citronella oil further enhances the mosquito repellent effect. The synergistic effect of these two plant essential oils may produce a better mosquito repellent effect than using them alone, while also increasing the aroma of the product and improving the user experience. The combination of caper fruit extract, peach cactus stem extract and olive leaf extract is another innovation. Caper fruit extract, peach cactus stem extract and olive leaf extract are all purchased from the market. These extracts each have different effects: Caper fruit extract: promotes cell regeneration and repair; peach cactus stem extract: anti-inflammatory, anti-oxidant, promotes wound healing; olive leaf extract: anti-oxidant, anti-inflammatory, antibacterial, the combination of these three extracts produces a synergistic effect, and together provides comprehensive skin protection and repair functions, especially for the repair of sunburned skin.

[0060] The addition of menthol (4%) not only provides a cooling sensation, but also relieves itching and has a calming effect. This complements the mosquito repellent function and can relieve discomfort after mosquito bites. The combination of methylpropanediol, trehalose and 1,2-hexanediol forms an effective moisturizing system. These ingredients not only lock in moisture, but also absorb moisture from the environment to keep the skin moisturized for a long time. This is very important for preventing dry skin and flaking after sun exposure. The combination of sorbitan olivate and cetearyl glucoside as emulsifiers of natural origin can form a stable emulsion system. This choice not only ensures the stability of the product, but also avoids the use of chemical synthetic emulsifiers that may cause skin irritation. The absence of alcohol in the formula is an important feature. This avoids the skin irritation and dryness that may be caused by alcohol, and is particularly suitable for sensitive skin and after sun use.

[0061] Capparis seed oil and Citronella oil provide effective mosquito repellent protection. Antioxidant protection: Olea europaea leaf extract and Opuntia cymbopogon extract have antioxidant effects that protect the skin from free radical damage. Antimicrobial protection: Olea europaea leaf extract and Citronella oil have antimicrobial effects that prevent skin infections. Capparis spinosa fruit extract promotes cell regeneration and accelerates the repair of sunburned skin. The anti-inflammatory effects of Opuntia cymbopogon extract and Olea europaea leaf extract can relieve redness and swelling after sunburn. Moisturizing ingredients such as trehalose prevent skin dehydration and accelerate the repair process. The cooling sensation provided by menthol can immediately relieve the burning sensation and discomfort of skin after sunburn. The combination of multiple moisturizing ingredients can provide long-lasting moisturizing effects and prevent skin dryness and peeling. The use of alcohol-free formula and natural plant extracts makes the product gentle on the skin and reduces the risk of irritation.

[0062] The main innovation of the present invention is to combine the traditional mosquito repellent function with modern skin care technology to create a multifunctional skin care product. It can not only effectively repel mosquitoes, but also provide comprehensive protection and repair functions for the skin.

[0063] It is particularly noteworthy that the formula cleverly utilizes the synergistic effect of natural plant extracts to achieve both effective mosquito repellent effect and comprehensive skin care function. This approach avoids the possible side effects of a single chemical ingredient, while also meeting the current consumer demand for natural and safe products.

[0064] In addition, the formula also performs well in resolving technical contradictions. For example, it can provide effective mosquito repellent effect without causing skin dryness or irritation; it can quickly relieve discomfort after sun exposure while providing long-term repair and protection. This balance of multiple effects is a major technical highlight of the product.

[0065] In general, this combination represents the fusion innovation of mosquito repellent products and skin care products, providing consumers with a new and multifunctional outdoor skin care solution. It not only meets practical needs, but also reflects the trend of modern cosmetics technology towards multi-effect, natural and safe development.

[0066] Example 1

[0067] This embodiment provides a composition with mosquito repellent, soothing and after-sun repair effects. The composition comprises the following components (by weight): 85.0 parts of water, 5.0 parts of methylpropanediol, 5.0 parts of olea europaea seed oil, 4.0 parts of menthol, 0.5 parts of sorbitan olivate, 0.5 parts of cetearyl glucoside, 0.5 parts of 1,2-hexanediol, 0.5 parts of citronella oil, 0.4 parts of phenoxyethanol, 0.05 parts of caper fruit extract, 0.0375 parts of chrysanthemum cactus stem extract, 0.045 parts of olive leaf extract, 0.1175 parts of maltodextrin, 0.1 parts of trehalose, 0.1 parts of carbomer, 0.1 parts of triethanolamine and 0.1 parts of ethylhexylglycerin.

[0068] The preparation method of the composition comprises the following steps:

[0069] First, prepare the oil phase. Add 5.0 parts of olea europaea seed oil, 0.5 parts of citronella oil, 0.5 parts of sorbitan olivate and 0.5 parts of cetearyl glucoside into a clean stainless steel reactor. Stir at 250 rpm for 17 minutes at 45°C until completely mixed. It is worth noting that olea europaea seed oil and citronella oil are the main mosquito repellent ingredients, and their synergistic effect can provide a more effective mosquito repellent effect. At the same time, the selection of these two natural essential oils not only ensures the effectiveness of the product, but also improves safety and environmental friendliness.

[0070] Next, prepare the water phase. In another clean stainless steel reactor, add 42.5 parts of purified water (half of the total water volume). At 23°C, slowly add 0.1 parts of carbomer and stir at 350rpm for 12 minutes until completely dispersed. Then add 5.0 parts of methylpropanediol, 0.5 parts of 1,2-hexanediol and 0.1 parts of trehalose and continue stirring for 7 minutes. The combination of these moisturizing ingredients constitutes an effective moisturizing system that not only locks in moisture, but also absorbs moisture from the environment to keep the skin moisturized for a long time, which is very important for preventing dry skin and peeling after sun exposure.

[0071] Next, the emulsification process is carried out. The oil phase is slowly added to the water phase at 47°C while stirring at 500rpm for 17 minutes until a uniform emulsion is formed. Sorbitan olivate and cetearyl glucoside, as emulsifiers of natural origin, can form a stable emulsion system, which not only ensures the stability of the product but also avoids the use of chemical synthetic emulsifiers that may cause skin irritation.

[0072] Then, add the active ingredients. At 50°C, add the following ingredients in order, stirring for 2.5 minutes after each addition: 4.0 parts of menthol, 0.05 parts of caper fruit extract, 0.0375 parts of opuntia cactus stem extract, and 0.045 parts of olive leaf extract. Add the remaining 42.5 parts of purified water and stir for 7 minutes. The combination of these plant extracts may produce a synergistic effect, jointly providing comprehensive skin protection and repair functions, especially for the repair of sunburned skin. Menthol not only provides a cooling sensation, but also has a soothing and calming effect on the skin, which complements the mosquito repellent function and can relieve the discomfort after mosquito bites.

[0073] Next, adjust the pH and preserve. At 37°C, slowly add 0.1 parts of triethanolamine to adjust the pH to 7.0. Add 0.4 parts of phenoxyethanol and 0.1 parts of ethylhexylglycerin and stir for 7 minutes. This alcohol-free formula avoids the skin irritation and dryness that alcohol may cause, and is especially suitable for sensitive skin and after sun exposure.

[0074] Finally, homogenize and cool. Use a high shear homogenizer at 7000 rpm for 12 minutes. Slowly cool to 23°C while maintaining a low speed of 150 rpm.

[0075] Preferably, in an embodiment of the present invention, the density (25°C) of the olea oleifera seed oil is 0.92 g / cm³, the refractive index (25°C) is 1.465, the acid value is 4.5 mg KOH / g, and the iodine value is 70 g I2 / 100g. The relative density (20°C) of the citronella oil is 0.890, the refractive index (20°C) is 1.480, the optical rotation is -2°, and the citral content is 80%. The total flavonoids content of the caper fruit extract is 6% (in terms of rutin), the total polysaccharide content of the celery cactus stem extract is 35%, and the total phenol content of the olive leaf extract is 18% (in terms of hydroxytyrosol). These characteristics ensure the high quality and effectiveness of each component, thereby ensuring the mosquito repellent, soothing and after-sun repair effects of the entire composition.

[0076] Example 2

[0077] This embodiment provides another composition with mosquito repellent, soothing and after-sun repair effects. The composition comprises the following components (by weight): 75.0 parts of water, 7.0 parts of methylpropanediol, 7.0 parts of olea europaea seed oil, 6.0 parts of menthol, 0.7 parts of sorbitan olivate, 0.7 parts of cetearyl glucoside, 0.7 parts of 1,2-hexanediol, 0.7 parts of citronella oil, 0.6 parts of phenoxyethanol, 0.07 parts of caper fruit extract, 0.05 parts of chrysanthemum cactus stem extract, 0.06 parts of olive leaf extract, 0.15 parts of maltodextrin, 0.12 parts of trehalose, 0.12 parts of carbomer, 0.12 parts of triethanolamine and 0.12 parts of ethylhexylglycerin.

[0078] The preparation method of the composition comprises the following steps:

[0079] First, prepare the oil phase. Add 7.0 parts of balsam oil, 0.7 parts of citronella oil, 0.7 parts of sorbitan olivate and 0.7 parts of cetearyl glucoside into a clean stainless steel reactor. Stir at 300 rpm for 20 minutes at 50°C until the mixture is completely mixed. The content of mosquito repellent active ingredients is increased here to provide a stronger mosquito repellent effect, which is particularly suitable for use in seasons or areas where mosquitoes are active.

[0080] Next, prepare the water phase. In another clean stainless steel reactor, add 37.5 parts of purified water (half the total amount of water). At 25°C, slowly add 0.12 parts of carbomer and stir at 400 rpm for 15 minutes until completely dispersed. Then add 7.0 parts of methylpropanediol, 0.7 parts of 1,2-hexanediol and 0.12 parts of trehalose and continue stirring for 10 minutes. This formula has a higher content of moisturizing ingredients, which can provide stronger moisturizing effects for the skin, especially suitable for dry climates or after-sun skin care.

[0081] Next, the emulsification process is carried out. The oil phase is slowly added to the water phase at 50°C while stirring at 600rpm for 20 minutes until a uniform emulsion is formed. Higher emulsifier content and stronger stirring conditions help form a more stable emulsion system and improve the long-term stability of the product.

[0082] Then, add the active ingredients. At 55°C, add the following ingredients in order, stirring for 3 minutes after each addition: 6.0 parts of menthol, 0.07 parts of caper fruit extract, 0.05 parts of opuntia cactus stem extract, 0.06 parts of olive leaf extract. Add the remaining 37.5 parts of purified water and stir for 10 minutes. This formula has increased the content of active plant extracts to provide stronger anti-inflammatory, antioxidant and repair effects, especially suitable for repairing severely sunburned or sensitive skin.

[0083] Next, pH adjustment and preservation are performed. At 40°C, slowly add 0.12 parts of triethanolamine to adjust the pH to 7.5. Add 0.6 parts of phenoxyethanol and 0.12 parts of ethylhexylglycerin and stir for 10 minutes. A higher level of preservatives can provide better microbial protection and extend the shelf life of the product.

[0084] Finally, homogenize and cool. Use a high shear homogenizer and homogenize at 8000rpm for 15 minutes. Slowly cool to 20℃, while maintaining a low-speed stirring of 200rpm. This stronger homogenization condition can produce a more delicate emulsion structure, improving the texture and user experience of the product.

[0085] Preferably, in an embodiment of the present invention, the density (25°C) of the olea oleifera seed oil is 0.93 g / cm³, the refractive index (25°C) is 1.470, the acid value is 3.5 mg KOH / g, and the iodine value is 75 g I2 / 100g. The relative density (20°C) of the citronella oil is 0.900, the refractive index (20°C) is 1.490, the optical rotation is +2°, and the citral content is 85%. The total flavonoids content of the caper fruit extract is 7% (in terms of rutin), the total polysaccharide content of the celery cactus stem extract is 40%, and the total phenol content of the olive leaf extract is 20% (in terms of hydroxytyrosol). These parameters indicate that each component is in a high-quality range, which is conducive to exerting the best efficacy.

[0086] Example 3

[0087] This embodiment provides a composition with mosquito repellent, soothing and after-sun repair effects. The composition comprises the following components (by weight): 90.0 parts of water, 3.0 parts of methylpropanediol, 3.0 parts of olea europaea seed oil, 2.0 parts of menthol, 0.3 parts of sorbitan olivate, 0.3 parts of cetearyl glucoside, 0.3 parts of 1,2-hexanediol, 0.3 parts of citronella oil, 0.2 parts of phenoxyethanol, 0.03 parts of caper fruit extract, 0.02 parts of chrysanthemum cactus stem extract, 0.03 parts of olive leaf extract, 0.08 parts of maltodextrin, 0.08 parts of trehalose, 0.08 parts of carbomer, 0.08 parts of triethanolamine and 0.08 parts of ethylhexylglycerin.

[0088] The preparation method of the composition comprises the following steps:

[0089] First, prepare the oil phase. Add 3.0 parts of balsam oil, 0.3 parts of citronella oil, 0.3 parts of sorbitan olivate, and 0.3 parts of cetearyl glucoside to a clean stainless steel reactor. Stir at 200 rpm for 15 minutes at 40°C until completely mixed. This formula has a lower content of oil phase ingredients and is suitable for making lighter products, especially suitable for summer or oily skin.

[0090] Next, prepare the water phase. In another clean stainless steel reactor, add 45.0 parts of purified water (half the total amount of water). At 20°C, slowly add 0.08 parts of carbomer and stir at 300 rpm for 10 minutes until fully dispersed. Then add 3.0 parts of methylpropanediol, 0.3 parts of 1,2-hexanediol, and 0.08 parts of trehalose and continue stirring for 5 minutes. This formula has a higher water content, which can provide a more refreshing and easier to absorb experience.

[0091] Next, the emulsification process is carried out. The oil phase is slowly added to the water phase at 40°C while stirring at 400 rpm for 15 minutes until a uniform emulsion is formed. The lower emulsification temperature and stirring speed help protect heat-sensitive ingredients and maintain their activity.

[0092] Then, add the active ingredients. At 45°C, add the following ingredients in order, stirring for 2 minutes after each addition: 2.0 parts of menthol, 0.03 parts of Capparis spinosa fruit extract, 0.02 parts of Opuntia ficus-indica stem extract, 0.03 parts of Olea europaea leaf extract. Add the remaining 45.0 parts of purified water and stir for 5 minutes. This formula has a low active ingredient content and is suitable for daily use or sensitive skin, providing a gentle care effect.

[0093] Next, pH adjustment and preservation are performed. At 35°C, slowly add 0.08 parts of triethanolamine to adjust the pH to 6.5. Add 0.2 parts of phenoxyethanol and 0.08 parts of ethylhexylglycerin and stir for 5 minutes. This formula has a lower pH value, which is closer to the natural pH value of the skin and helps maintain the acid-base balance of the skin.

[0094] Finally, homogenize and cool. Use a high shear homogenizer and homogenize at 5000 rpm for 10 minutes. Slowly cool to 25°C while maintaining a low speed of 100 rpm. This milder homogenization condition is suitable for protecting the active ingredients while still ensuring the stability of the emulsion.

[0095] Preferably, in an embodiment of the present invention, the density (25°C) of the olea oleifera seed oil is 0.90 g / cm³, the refractive index (25°C) is 1.460, the acid value is 5.0 mg KOH / g, and the iodine value is 60 g I2 / 100g. The relative density (20°C) of the citronella oil is 0.880, the refractive index (20°C) is 1.470, the optical rotation is -5°, and the citral content is 75%. The total flavonoids content of the caper fruit extract is 5% (in terms of rutin), the total polysaccharide content of the chrysanthemum cactus stem extract is 30%, and the total phenol content of the olive leaf extract is 15% (in terms of hydroxytyrosol). These parameters indicate that each component is within the standard range, ensuring the basic efficacy.

[0096] Example 4

[0097] This embodiment provides a composition with mosquito repellent, soothing and after-sun repair effects. The composition comprises the following components (in parts by weight): 82.5 parts of water, 5.5 parts of methylpropanediol, 5.5 parts of olea europaea seed oil, 4.5 parts of menthol, 0.5 parts of sorbitan olivate, 0.5 parts of cetearyl glucoside, 0.5 parts of 1,2-hexanediol, 0.5 parts of citronella oil, 0.4 parts of phenoxyethanol, 0.05 parts of caper fruit extract, 0.04 parts of chrysanthemum cactus stem extract, 0.05 parts of olive leaf extract, 0.12 parts of maltodextrin, 0.1 parts of trehalose, 0.1 parts of carbomer, 0.1 parts of triethanolamine and 0.1 parts of ethylhexylglycerin.

[0098] The preparation method of the composition comprises the following steps:

[0099] First, prepare the oil phase. Add 5.5 parts of balsam oil, 0.5 parts of citronella oil, 0.5 parts of sorbitan olivate and 0.5 parts of cetearyl glucoside into a clean stainless steel reactor. Stir at 270 rpm for 18 minutes at 46°C until the mixture is completely mixed. This formula has a moderate content of oil phase ingredients, balancing the mosquito repellent effect and comfort.

[0100] Next, prepare the water phase. In another clean stainless steel reactor, add 41.25 parts of purified water (half the total amount of water). Slowly add 0.1 parts of carbomer at 22°C and stir at 370 rpm for 13 minutes until completely dispersed. Then add 5.5 parts of methylpropanediol, 0.5 parts of 1,2-hexanediol and 0.1 parts of trehalose and continue stirring for 8 minutes. This formula has the right ratio of moisturizing ingredients to provide good moisturizing effect without making the skin feel too sticky.

[0101] Next, the emulsification process is carried out. The oil phase is slowly added to the water phase at 47°C while stirring at 530 rpm for 18 minutes until a uniform emulsion is formed. This medium-intensity emulsification condition can form a stable emulsion system while maintaining a good texture.

[0102] Then, add the active ingredients. At 50°C, add the following ingredients in order, stirring for 2.7 minutes after each addition: 4.5 parts menthol, 0.05 parts caper fruit extract, 0.04 parts opuntia cactus stem extract, 0.05 parts olive leaf extract. Add the remaining 41.25 parts purified water and stir for 8 minutes. This formula has a moderate amount of active ingredients and provides a balanced mosquito repellent, soothing and repairing effect.

[0103] Next, adjust the pH and preserve the product. At 38°C, slowly add 0.1 parts of triethanolamine to adjust the pH to 7.2. Add 0.4 parts of phenoxyethanol and 0.1 parts of ethylhexylglycerin and stir for 8 minutes. This pH value and preservative content are moderate, which can ensure the stability of the product without causing irritation to the skin.

[0104] Finally, homogenize and cool. Use a high shear homogenizer and homogenize at 7000 rpm for 13 minutes. Slowly cool to 22°C while maintaining a low-speed stirring of 170 rpm. This homogenization condition ensures the fineness and stability of the emulsion without excessively destroying the active ingredients.

[0105] Preferably, in an embodiment of the present invention, the density (25°C) of the oleifera seed oil is 0.915 g / cm³, the refractive index (25°C) is 1.465, the acid value is 4.2 mg KOH / g, and the iodine value is 67 g I2 / 100g. The relative density (20°C) of the citronella oil is 0.890, the refractive index (20°C) is 1.480, the optical rotation is -1°, and the citral content is 82%. The total flavonoids content of the caper fruit extract is 6.5% (in terms of rutin), the total polysaccharide content of the celery cactus stem extract is 37%, and the total phenol content of the olive leaf extract is 19% (in terms of hydroxytyrosol). These parameters indicate that the quality of each component is at a high level, which is conducive to exerting a good comprehensive effect.

[0106] Example 5

[0107] This embodiment provides a composition with mosquito repellent, soothing and after-sun repair effects. The composition comprises the following components (by weight): 78.0 parts of water, 6.5 parts of methylpropanediol, 6.5 parts of olea europaea seed oil, 5.5 parts of menthol, 0.6 parts of sorbitan olivate, 0.6 parts of cetearyl glucoside, 0.6 parts of 1,2-hexanediol, 0.6 parts of citronella oil, 0.5 parts of phenoxyethanol, 0.06 parts of caper fruit extract, 0.045 parts of chrysanthemum cactus stem extract, 0.055 parts of olive leaf extract, 0.14 parts of maltodextrin, 0.11 parts of trehalose, 0.11 parts of carbomer, 0.11 parts of triethanolamine and 0.11 parts of ethylhexylglycerin.

[0108] The preparation method of the composition comprises the following steps:

[0109] First, prepare the oil phase. Add 6.5 parts of calendula seed oil, 0.6 parts of citronella oil, 0.6 parts of sorbitan olivate and 0.6 parts of cetearyl glucoside into a clean stainless steel reactor. Stir at 280 rpm for 19 minutes at 48°C until the mixture is completely mixed. This formula has a high content of mosquito repellent active ingredients and is suitable for use in environments where mosquitoes are active.

[0110] Next, prepare the water phase. In another clean stainless steel reactor, add 39.0 parts of purified water (half of the total water volume). At 24°C, slowly add 0.11 parts of carbomer and stir at 380 rpm for 14 minutes until completely dispersed. Then add 6.5 parts of methylpropanediol, 0.6 parts of 1,2-hexanediol and 0.11 parts of trehalose and continue stirring for 9 minutes. This formula has a high content of moisturizing ingredients, which can provide stronger moisturizing effects for the skin and is particularly suitable for use in dry environments or after sun exposure.

[0111] Next, the emulsification process is carried out. The oil phase is slowly added to the water phase at 49°C while stirring at 570rpm for 19 minutes until a uniform emulsion is formed. This stronger emulsification condition can form a more stable emulsion system, which is beneficial to the long-term stability of the product.

[0112] Then, add the active ingredients. At 53°C, add the following ingredients in order, stirring for 2.8 minutes after each addition: 5.5 parts menthol, 0.06 parts caper fruit extract, 0.045 parts opuntia cactus stem extract, 0.055 parts olive leaf extract. Add the remaining 39.0 parts purified water and stir for 9 minutes. This formula has a higher content of active ingredients and can provide stronger soothing and repairing effects, especially suitable for severely sunburned or sensitive skin.

[0113] Next, pH adjustment and preservation were performed. At 39°C, 0.11 parts of triethanolamine were slowly added to adjust the pH to 7.3. 0.5 parts of phenoxyethanol and 0.11 parts of ethylhexylglycerin were added and stirred for 9 minutes. This formula has a higher preservative content, which can provide better microbial protection and extend the shelf life of the product.

[0114] Finally, homogenize and cool. Use a high shear homogenizer and homogenize at 7500rpm for 14 minutes. Slowly cool to 21°C while maintaining a low-speed stirring of 180rpm. This strong homogenization condition can produce a more delicate emulsion structure, improving the texture and user experience of the product.

[0115] Preferably, in an embodiment of the present invention, the density (25°C) of the oleifera seed oil is 0.925 g / cm³, the refractive index (25°C) is 1.468, the acid value is 3.8 mg KOH / g, and the iodine value is 72 g I2 / 100g. The relative density (20°C) of citronella oil is 0.895, the refractive index (20°C) is 1.485, the optical rotation is 0°, and the citral content is 83%. The total flavonoids content of the caper fruit extract is 6.8% (in terms of rutin), the total polysaccharide content of the celery cactus stem extract is 38%, and the total phenol content of the olive leaf extract is 19.5% (in terms of hydroxytyrosol). These parameters indicate that each component is in a high quality range, which is conducive to exerting a stronger effect.

[0116] Example 6

[0117] This embodiment provides a composition with mosquito repellent, soothing and after-sun repair effects. The composition comprises the following components (by weight): 87.5 parts of water, 4.0 parts of methylpropanediol, 4.0 parts of olea europaea seed oil, 3.0 parts of menthol, 0.4 parts of sorbitan olivate, 0.4 parts of cetearyl glucoside, 0.4 parts of 1,2-hexanediol, 0.4 parts of citronella oil, 0.3 parts of phenoxyethanol, 0.04 parts of caper fruit extract, 0.03 parts of chrysanthemum cactus stem extract, 0.04 parts of olive leaf extract, 0.1 parts of maltodextrin, 0.09 parts of trehalose, 0.09 parts of carbomer, 0.09 parts of triethanolamine and 0.09 parts of ethylhexylglycerin.

[0118] The preparation method of the composition comprises the following steps:

[0119] First, prepare the oil phase. Add 4.0 parts of calendula seed oil, 0.4 parts of citronella oil, 0.4 parts of sorbitan olivate and 0.4 parts of cetearyl glucoside to a clean stainless steel reactor. Stir at 230 rpm for 16 minutes at 43°C until the mixture is thoroughly mixed. This formula contains a moderate amount of mosquito repellent active ingredients, providing effective mosquito repellent effects while maintaining a lighter texture.

[0120] Next, prepare the water phase. In another clean stainless steel reactor, add 43.75 parts of purified water (half the total amount of water). At 21°C, slowly add 0.09 parts of carbomer and stir at 330 rpm for 11 minutes until completely dispersed. Then add 4.0 parts of methylpropanediol, 0.4 parts of 1,2-hexanediol, and 0.09 parts of trehalose and continue stirring for 6 minutes. This formula has a high water content and provides a refreshing and easily absorbed experience, suitable for summer or oily skin.

[0121] Next, the emulsification process is carried out. The oil phase is slowly added to the water phase at 44°C while stirring at 450 rpm for 16 minutes until a uniform emulsion is formed. This medium-intensity emulsification condition can form a stable emulsion system while maintaining a good texture.

[0122] Then, add the active ingredients. At 47°C, add the following ingredients in order, stirring for 2.3 minutes after each addition: 3.0 parts menthol, 0.04 parts capparis fruit extract, 0.03 parts opuntia cactus stem extract, add the active ingredients. At 47°C, add the following ingredients in order, stirring for 2.3 minutes after each addition: 3.0 parts menthol, 0.04 parts capparis fruit extract, 0.03 parts opuntia cactus stem extract, 0.04 parts olive leaf extract. Add the remaining 43.75 parts purified water and stir for 6 minutes. This formula has a moderate amount of active ingredients and provides a balanced soothing and repairing effect, suitable for daily use.

[0123] Next, pH adjustment and preservation are performed. At 36°C, slowly add 0.09 parts of triethanolamine to adjust the pH to 6.8. Add 0.3 parts of phenoxyethanol and 0.09 parts of ethylhexylglycerin and stir for 6 minutes. This pH value is close to the natural pH value of the skin, which helps maintain the acid-base balance of the skin while providing a moderate preservative effect.

[0124] Finally, homogenize and cool. Use a high shear homogenizer and homogenize at 6000 rpm for 11 minutes. Slowly cool to 24°C while maintaining a low-speed stirring of 130 rpm. This medium-intensity homogenization condition ensures the fineness and stability of the emulsion without excessively destroying the active ingredients.

[0125] Preferably, in an embodiment of the present invention, the density (25°C) of the olea oleifera seed oil is 0.91 g / cm³, the refractive index (25°C) is 1.463, the acid value is 4.7 mg KOH / g, and the iodine value is 63 g I2 / 100g. The relative density (20°C) of the citronella oil is 0.885, the refractive index (20°C) is 1.475, the optical rotation is -3°, and the citral content is 78%. The total flavonoids content of the caper fruit extract is 5.5% (in terms of rutin), the total polysaccharide content of the chrysanthemum cactus stem extract is 33%, and the total phenol content of the olive leaf extract is 16.5% (in terms of hydroxytyrosol). These parameters indicate that the quality of each component is within the standard range, ensuring the basic efficacy.

[0126] Through the above six embodiments, it can be seen that the composition of the present invention can achieve the expected mosquito repellent, soothing and after-sun repair effects under different proportions and preparation conditions.

[0127] For example, the water content ranges from 75.0 to 90.0 parts, which can adjust the texture and feel of the product as needed. The content of mosquito repellent active ingredients such as calendula seed oil and citronella oil also varies, which can adjust the intensity of the mosquito repellent effect according to the use environment and needs. The content of moisturizing ingredients such as methylpropanediol and trehalose allows the moisturizing effect to be adjusted according to different skin types and climate conditions.

[0128] The changes in parameters such as temperature, stirring speed and time in the preparation method demonstrate the adaptability of the present invention under different production conditions. For example, the temperature of the oil phase preparation varies from 40°C to 50°C, and the stirring speed of the emulsification process varies from 400rpm to 600rpm, all of which may affect the texture and stability of the final product.

[0129] Comparative Example 1

[0130] This comparative example provides a mosquito repellent composition, which is compared with Example 1. The composition comprises the following components (in parts by weight): 85.0 parts of water, 5.0 parts of methylpropanediol, 5.0 parts of DEET (N,N-diethyl-m-toluamide), 4.0 parts of menthol, 0.5 parts of sorbitan olivate, and 0.5 parts of cetearyl glucoside.

[0131] The preparation method of the composition comprises the following steps:

[0132] First, prepare the oil phase. Add 5.0 parts of DEET, 0.5 parts of sorbitan olivate and 0.5 parts of cetearyl glucoside into a clean stainless steel reactor. Stir at 45°C and 250 rpm for 17 minutes until the mixture is completely mixed.

[0133] Next, prepare the aqueous phase. In another clean stainless steel reaction kettle, add 42.5 parts of purified water. Stir at 350 rpm for 12 minutes at 23°C. Then add 5.0 parts of methyl propanediol and continue stirring for 7 minutes.

[0134] Next, the emulsification process was performed. The oil phase was slowly added to the water phase at 47°C while stirring at 500 rpm for 17 minutes until a uniform emulsion was formed.

[0135] Then, the active ingredient was added. At 50°C, 4.0 parts of menthol were added and stirred for 2.5 minutes. The remaining 42.5 parts of purified water were added and stirred for 7 minutes.

[0136] Finally, homogenize and cool. Use a high shear homogenizer at 7000 rpm for 12 minutes. Slowly cool to 23°C while maintaining a low speed of 150 rpm.

[0137] Compared with Example 1, this comparative example uses the common chemical mosquito repellent DEET to replace the oleifera seed oil and citronella oil, and removes other plant extracts. Although DEET has a strong mosquito repellent effect, it lacks the synergistic effect and multiple effects of natural plant essential oils. For example, oleifera seed oil not only has a mosquito repellent effect, but also contains rich fatty acids and flavonoids, which can provide moisturizing and antioxidant effects for the skin. In addition to repelling mosquitoes, citronella oil also has a refreshing aromatic effect. In addition, this comparative example lacks caper fruit extract, fairy peach cactus stem extract and olive leaf extract, which play an important soothing and repairing role in the present invention. Therefore, it is expected that although this comparative example may have a strong mosquito repellent effect, the effect in skin soothing, moisturizing and after-sun repair will be significantly inferior to Example 1.

[0138] Comparative Example 2

[0139] This comparative example provides a soothing and repairing lotion, which is compared with Example 2. The composition comprises the following components (in parts by weight): 75.0 parts of water, 7.0 parts of methylpropanediol, 6.0 parts of aloe vera gel, 6.0 parts of menthol, 0.7 parts of sorbitan olivate, 0.7 parts of cetearyl glucoside, 0.7 parts of 1,2-hexanediol, 0.07 parts of caper fruit extract, 0.05 parts of chrysanthemum cactus stem extract, 0.06 parts of olive leaf extract, 0.15 parts of maltodextrin, 0.12 parts of trehalose, 0.12 parts of carbomer, 0.12 parts of triethanolamine, 0.6 parts of phenoxyethanol, and 0.12 parts of ethylhexylglycerin.

[0140] The preparation method of the present composition is substantially the same as that of Example 2, except that 6.0 parts of aloe vera gel are used in place of calendula seed oil and citronella oil in the oil phase preparation step.

[0141] Compared with Example 2, this comparative example removes the mosquito repellent component and adds aloe vera gel as the main soothing and repairing component. Aloe vera gel does have good moisturizing and soothing effects, but lacks the multiple functions of the oleifera seed oil and citronella oil in the present invention. The fatty acids contained in the oleifera seed oil not only have a mosquito repellent effect, but also can strengthen the skin barrier function, while citronella oil has natural antiseptic and antibacterial effects. This synergistic effect cannot be achieved in this comparative example. In addition, although this comparative example retains other plant extracts, it lacks mosquito repellent components and cannot provide comprehensive outdoor protection. Therefore, it is expected that this comparative example may perform well in soothing and moisturizing, but will not be as good as Example 2 in mosquito repellent and comprehensive skin protection.

[0142] Comparative Example 3

[0143] This comparative example provides a refreshing sunscreen lotion, which is compared with Example 3. The composition comprises the following components (parts by weight): 90.0 parts of water, 3.0 parts of methylpropanediol, 3.0 parts of titanium dioxide, 2.0 parts of menthol, 0.3 parts of sorbitan olivate, 0.3 parts of cetearyl glucoside, 0.3 parts of 1,2-hexanediol, 0.03 parts of caper fruit extract, 0.02 parts of celery cactus stem extract, 0.03 parts of olive leaf extract, 0.08 parts of maltodextrin, 0.08 parts of trehalose, 0.08 parts of carbomer, 0.08 parts of triethanolamine, 0.2 parts of phenoxyethanol, and 0.08 parts of ethylhexylglycerin.

[0144] The preparation method of the present composition is substantially the same as that of Example 3, except that 3.0 parts of titanium dioxide are used to replace calendula seed oil and citronella oil in the oil phase preparation step.

[0145] Compared with Example 3, this comparative example replaces the mosquito repellent ingredient with the physical sunscreen titanium dioxide. Although titanium dioxide can provide good sun protection, it lacks the multiple functions of the natural plant essential oils in the present invention. The balsam pear seed oil and the citronella oil not only have mosquito repellent effects, but also provide antioxidant and anti-inflammatory effects for the skin, which plays an important role in skin repair after sun protection. In addition, although this comparative example retains other plant extracts, it cannot provide comprehensive outdoor protection due to the lack of mosquito repellent ingredients. It is expected that this comparative example may perform well in terms of sun protection and cooling effects, but the comprehensive effects in terms of mosquito repellent and after-sun repair will not be as good as Example 3.

[0146] Comparative Example 4

[0147] This comparative example provides a moisturizing mosquito repellent spray, which is compared with Example 4. The composition comprises the following components (in parts by weight): 82.5 parts of water, 5.5 parts of glycerin, 5.5 parts of lemon eucalyptus oil, 4.5 parts of menthol, 0.5 parts of polysorbate 20, 0.5 parts of 1,2-hexanediol, 0.1 parts of trehalose, 0.1 parts of carbomer, 0.1 parts of triethanolamine, 0.4 parts of phenoxyethanol, and 0.1 parts of ethylhexylglycerin.

[0148] The preparation method of this composition is similar to that of Example 4, but some steps are simplified:

[0149] First, 5.5 parts of lemon eucalyptus oil and 0.5 parts of polysorbate 20 were mixed at 46° C. and stirred for 18 minutes.

[0150] Next, in another container, 82.5 parts of water, 5.5 parts of glycerin, 0.5 parts of 1,2-hexanediol, and 0.1 parts of trehalose were mixed and stirred at 22° C. for 13 minutes.

[0151] Then, the oil phase was slowly added to the water phase and stirred at 47°C for 18 minutes.

[0152] Finally, menthol, carbomer, triethanolamine, phenoxyethanol and ethylhexylglycerin were added in sequence, the pH was adjusted to 7.2, and then homogenized at 7000 rpm for 13 minutes.

[0153] Compared with Example 4, this comparative example uses a single lemon eucalyptus oil as a mosquito repellent ingredient, and removes the synergistic effect of oleoresin seed oil and citronella oil. Although lemon eucalyptus oil also has a certain mosquito repellent effect, it lacks the fatty acids and flavonoids in oleoresin seed oil, which not only enhance the mosquito repellent effect in the present invention, but also provide additional skin protection. In addition, this comparative example removes all plant extracts and loses the anti-inflammatory, antioxidant and repair effects they provide. It is expected that although this comparative example has a certain mosquito repellent and moisturizing effect, it will be significantly inferior to Example 4 in terms of comprehensive skin protection and repair.

[0154] Comparative Example 5

[0155] This comparative example provides a natural mosquito repellent cream for comparison with Example 5. The composition comprises the following components (in parts by weight): 35.0 parts of water, 43.0 parts of paraffin, 6.5 parts of calendula seed oil, 0.6 parts of citronella oil, 10.0 parts of beeswax, 4.0 parts of menthol, 0.5 parts of vitamin E, and 0.4 parts of phenoxyethanol.

[0156] The preparation method of this composition is as follows:

[0157] First, 43.0 parts of paraffin wax and 10.0 parts of beeswax were melted at 70°C and stirred until uniform.

[0158] Next, 6.5 parts of calendula seed oil and 0.6 parts of citronella oil were added to the above mixture, and stirred at 60° C. for 15 minutes.

[0159] Then, in another container, 35.0 parts of water were heated to 60°C.

[0160] Next, slowly add the oil phase to the water phase while stirring vigorously until a homogeneous emulsion is formed.

[0161] Finally, when the temperature dropped to 40° C., 4.0 parts of menthol, 0.5 parts of vitamin E and 0.4 parts of phenoxyethanol were added, and stirring was continued until the temperature reached room temperature.

[0162] Compared with Example 5, this comparative example adopts the traditional mosquito repellent cream formula, which mainly relies on high concentrations of oleifera seed oil and citronella oil to provide mosquito repellent effect. Although the main mosquito repellent ingredients are retained, the various plant extracts and moisturizing ingredients in the present invention are missing. Although the use of paraffin and beeswax can provide lasting protection, it may cause the skin to feel greasy and clog pores. In addition, due to the lack of caper fruit extract, peach cactus stem extract and olive leaf extract, the effect of this comparative example in skin soothing and repair will be greatly reduced. It is expected that this comparative example may have a strong mosquito repellent effect and durability, but it will not be as good as Example 5 in terms of comfort, skin friendliness and versatility.

[0163] Comparative Example 6

[0164] This comparative example provides a simplified version of a mosquito repellent skin care lotion, which is compared with Example 6. The composition comprises the following components (in parts by weight): 87.5 parts of water, 4.0 parts of glycerin, 4.0 parts of oleifera seed oil, 3.0 parts of menthol, 0.4 parts of cetearyl glucoside, 0.4 parts of 1,2-hexanediol, 0.09 parts of carbomer, 0.09 parts of triethanolamine, 0.3 parts of phenoxyethanol, and 0.09 parts of ethylhexylglycerin.

[0165] The preparation method of this composition is similar to that of Example 6, but some steps are simplified:

[0166] First, 4.0 parts of karaya seed oil and 0.4 parts of cetearyl glucoside were mixed at 43° C. and stirred for 16 minutes.

[0167] Next, in another container, 87.5 parts of water, 4.0 parts of glycerin, and 0.4 parts of 1,2-hexanediol were mixed and stirred at 21° C. for 11 minutes.

[0168] Then, the oil phase was slowly added to the water phase and stirred at 44°C for 16 minutes.

[0169] Finally, menthol, carbomer, triethanolamine, phenoxyethanol and ethylhexylglycerin were added in sequence, the pH was adjusted to 6.8, and then homogenized at 6000 rpm for 11 minutes.

[0170] Compared with Example 6, this comparative example retains the main mosquito repellent ingredient, olea europaea seed oil, but removes citronella oil, and loses the synergistic mosquito repellent effect of the two essential oils. In addition, this comparative example removes all plant extracts, including caper fruit extract, peach cactus stem extract and olive leaf extract, which play important anti-inflammatory, antioxidant and repairing effects in the present invention. Although the basic moisturizing ingredients are retained, the overall formula is greatly simplified. It is expected that this comparative example may have certain mosquito repellent and basic moisturizing effects, but it is expected that this comparative example may have certain mosquito repellent and basic moisturizing effects, but it will be significantly inferior to Example 6 in terms of versatility, skin soothing and repair. Especially in terms of after-sun repair and long-term skin protection, due to the lack of key plant extracts, its effect may be greatly reduced.

[0171] Through the above six comparative examples, we can clearly see the innovation and advantages of the present invention:

[0172] 1. Synergistic effect of mosquito repellent ingredients: The present invention uses a combination of calendula seed oil and citronella oil, which not only provides an effective mosquito repellent effect, but also avoids skin irritation that may be caused by chemical synthetic mosquito repellents. The single mosquito repellent ingredients used in Comparative Examples 1 and 4 are difficult to achieve such a synergistic effect.

[0173] 2. Comprehensive effects of multiple plant extracts: The Capparis spinosa fruit extract, Opuntia ficus-indica stem extract and Olea europaea leaf extract in the present invention provide anti-inflammatory, antioxidant and repairing effects together. This is missing in Comparative Examples 2, 3, 5 and 6, resulting in poor effects of these formulas in terms of skin protection and repair.

[0174] 3. Balanced formula design: The present invention achieves a good balance between mosquito repellent effect, skin soothing, moisturizing and after-sun repair. In contrast, Comparative Example 2 focuses on soothing and repairing but lacks mosquito repellent effect, Comparative Example 3 focuses on sun protection but ignores mosquito repellent and deep repair, and Comparative Example 5 may have a stronger mosquito repellent effect but poor user experience and skin friendliness.

[0175] 4. Optimization of preparation process: The preparation method of the present invention fully considers the characteristics of various ingredients, such as mild emulsification conditions and precisely controlled pH values, which ensures the stability and effectiveness of the active ingredients. In contrast, the high temperature preparation of Comparative Example 5 may affect the activity of certain heat-sensitive ingredients.

[0176] 5. Comprehensive outdoor protection: The present invention not only provides mosquito repellent effect, but also protects against oxidative damage caused by ultraviolet rays and provides repair after sun exposure. This comprehensive protection is not achievable in the comparative examples with a single function.

[0177] In summary, these comparative examples fully demonstrate the innovation and superiority of the present invention in terms of formula design, functionality and user experience. The present invention achieves multiple functions of mosquito repelling, soothing and after-sun repair by carefully selecting and proportioning various natural active ingredients, providing users with a comprehensive outdoor skin protection solution.

[0178] The present invention also designs a series of experiments to comprehensively evaluate the efficacy of the product. These experiments not only verify the mosquito repellent, soothing and after-sun repair effects of the product, but also explore the synergistic effects between the various components.

[0179] 1. Evaluation of mosquito repellent effect

[0180] Test method: Refer to GB / T 13917.9-2009 "Indoor efficacy test and evaluation of registered pesticides and hygienic insecticides Part 9: Repellents"

[0181] Specific steps:

[0182] (1) Preparation: Select four healthy volunteers and draw a 50 mm × 50 mm test area on the back of each of their hands.

[0183] (2) Sample preparation: Apply the test product evenly at a dose of 1.5 μL / cm² to the test area of ​​one hand, and use the other hand as a blank control.

[0184] (3) Mosquito preparation: Select female Aedes albopictus that have not fed blood for 3-5 days after emergence.

[0185] (4) Test conditions: temperature 26.3°C, relative humidity 62.6%.

[0186] (5) Repellent test: First, place the control hand in a mosquito cage for 2 minutes and record the number of mosquitoes landing. Then place the hand coated with the product in a mosquito cage for 2 minutes and also record the number of mosquitoes landing.

[0187] (6) Data processing: The repellency rate was calculated using the formula P = (NK) / N × 100%, where N is the number of mosquitoes landing in the control group and K is the number of mosquitoes landing in the experimental group.

[0188] References:

[0189] [1] General Administration of Quality Supervision, Inspection and Quarantine of the People's Republic of China. GB / T 13917.9-2009 Indoor efficacy test and evaluation of pesticides for pesticide registration Part 9: Repellents [S]. Beijing: China Standards Press, 2009.

[0190] 2. Soothing effect evaluation (hyaluronidase inhibition rate test)

[0191] Test method: Refer to "Cosmetic efficacy evaluation method - Determination of hyaluronidase inhibition activity"

[0192] Specific steps:

[0193] (1) Sample preparation: Dilute the test sample to 100 mg / mL.

[0194] (2) Enzyme reaction:

[0195] a. Take 0.5 mL of the test sample solution and 0.5 mL of the hyaluronidase solution and incubate at 37°C for 20 min;

[0196] b. Add 0.1 mL of CaCl2 solution and incubate at 37°C for 20 min;

[0197] c. Add 0.5 mL of sodium hyaluronate solution, keep at 37°C for 40 minutes, and leave at room temperature for 10 minutes;

[0198] d. Add 0.5 mL of distilled water, 0.1 mL of NaOH solution and 0.5 mL of acetylacetone solution, heat in boiling water for 15 min, take out and cool with ice water for 10 min.

[0199] (3) Color development reaction: Add 5 mL of DAB-1.0 mL of horseradish peroxidase color development reagent, shake each test tube thoroughly, add anhydrous ethanol to 8 mL, and leave at room temperature for 30 min.

[0200] (4) Determination: Measure the absorbance at 530 nm.

[0201] (5) Data processing: Calculate the ability of samples to inhibit hyaluronidase activity and perform statistical difference analysis.

[0202] References:

[0203] [2] Liu Fang, Cao Xiaoxi, Sun Ruolin, et al. Cosmetic efficacy evaluation method - Determination of hyaluronidase inhibition activity [J]. Chinese Cosmetics, 2015, 24(6): 28-31.

[0204] 3. Evaluation of after-sun repair efficacy (zebrafish model)

[0205] Test method: Refer to "A method for evaluating antioxidant and spot-lightening effects using a zebrafish model"

[0206] Specific steps:

[0207] (1) Zebrafish preparation: Wild-type AB zebrafish at 3 days post fertilization (dpf) were used.

[0208] (2) Grouping: Zebrafish were randomly divided into a control group, a model group, and a sample group, with 10 zebrafish in each group.

[0209] (3) Model establishment: The zebrafish in the model group and the sample group were tail-clipped to simulate sunburn damage.

[0210] (4) Sample treatment: The zebrafish in the sample group were placed in a 0.1% product solution.

[0211] (5) Cultivation: Cultivate at 28°C for 48 hours.

[0212] (6) Observation and measurement: Use a stereo microscope to observe and take pictures, and use Image J software to measure the tail regeneration area.

[0213] (7) Data analysis: Statistical analysis was performed, and p < 0.05 was considered to be a significant difference.

[0214] References:

[0215] [3] Xu Yiqiao, Chen Xinghui, Huang Yanfeng, et al. A method for evaluating antioxidant and freckle-lightening effects using a zebrafish model: CN202010872184.6[P].

[0216] 4. Skin irritation test

[0217] Test method: Refer to Chapter 6 Toxicology Test Method 4 Skin Irritation / Corrosion Test of the 2015 Edition of the "Technical Specifications for Safety of Cosmetics"

[0218] Specific steps:

[0219] (1) Animal selection: Four healthy New Zealand white rabbits weighing approximately 2.5 kg were selected.

[0220] (2) Skin preparation: 24 hours before the experiment, the hair on both sides of the spine on the back of the animal was shaved to expose a skin area of ​​approximately 3 cm × 3 cm.

[0221] (3) Sample preparation: Use stock solution samples.

[0222] (4) Administration: Apply 0.5 mL of the sample to the shaved area with an area of ​​2.5 cm × 2.5 cm. The other side serves as a control.

[0223] (5) Observation: Apply once a day for 14 consecutive days. Starting from the second day, observe and score the skin reaction before each application.

[0224] (6) Scoring criteria: Scoring is based on the degree of erythema and edema.

[0225] (7) Data processing: Calculate the average score of each animal within 14 days and determine the irritation level.

[0226] References:

[0227] [4] China Food and Drug Administration. Cosmetic Safety Technical Specifications (2015 Edition)[S]. Beijing: China Standards Press, 2015.

[0228] 5. Evaluation of antioxidant activity (DPPH free radical scavenging ability assay)

[0229] Test method: Refer to "Cosmetic efficacy evaluation method in vitro antioxidant activity determination"

[0230] Specific steps:

[0231] (1) Sample preparation: The test samples were prepared into solutions of different concentrations (50-500 μg / mL).

[0232] (2) Preparation of DPPH solution: Prepare 0.1 mmol / L DPPH solution using anhydrous ethanol.

[0233] (3) Reaction: Take 2 mL of sample solution of different concentrations, add 2 mL of DPPH solution, mix well and react in the dark for 30 min.

[0234] (4) Measurement: Measure the absorbance at a wavelength of 517 nm.

[0235] (5) Control: Use vitamin C as a positive control.

[0236] (6) Calculation: DPPH free radical scavenging rate (%) = [1-(A sample-A sample blank) / A control] × 100%

[0237] Among them, A sample is the absorbance of the sample after the reaction with DPPH, A sample blank is the absorbance of the sample itself, and A control is the absorbance of the DPPH solution.

[0238] (7) Data processing: draw the clearance-concentration curve and calculate the IC50 value.

[0239] These detailed test methods not only cover the main effects of the present invention (mosquito repellent, soothing, repairing, safety and antioxidant activity evaluation) to further prove the inventiveness of the present invention. Each method is based on national standards or authoritative literature to ensure the reliability and repeatability of the test results.

[0240] The following are the test results of each embodiment and comparative example, as well as the related analysis and discussion:

[0241] 1. Evaluation results of mosquito repellent effect

[0242] Table 1: Mosquito repellent effect evaluation results (repellent rate %)

[0243]

[0244] 2. Soothing effect evaluation results (hyaluronidase inhibition rate %)

[0245] Table 2 Soothing effect evaluation results

[0246]

[0247] 3. Evaluation results of after-sun repair efficacy (% of zebrafish tail regeneration area)

[0248] Table 3: After-sun repair efficacy evaluation results

[0249]

[0250] 4. Skin irritation test results

[0251] Table 4: Skin irritation test results (14-day average score)

[0252]

[0253] 5. Antioxidant activity evaluation results (DPPH free radical scavenging ability, IC50 value, μg / mL)

[0254] Table 5: Antioxidant activity evaluation results

[0255]

[0256] Analysis and discussion:

[0257] 1. Best Example: According to the comprehensive evaluation results, Example 4 performed best. It achieved the best or near-best performance in terms of mosquito repellent durability, soothing effect, after-sun repair and antioxidant activity, while maintaining zero skin irritation.

[0258] 2. Superiority analysis:

[0259] a) Mosquito repellent effect: All examples achieved 100% instant mosquito repellent effect, and the persistence was significantly better than the comparative examples, including DEET (Comparative Example 1). This shows that the natural formula of the present invention can not only achieve the effect of chemical mosquito repellents, but also has better persistence.

[0260] b) Soothing effect: The hyaluronidase inhibition rate of the examples was significantly higher than that of the comparative examples, especially that of Example 4, which reached 37.42%. This result proves the excellent performance of the present invention in soothing the skin.

[0261] c) After-sun repair: The examples showed significant repair effects in the zebrafish model, far exceeding the control examples. The tail regeneration area ratio of Example 4 reached 186.9%, which highlights the unique advantages of the present invention in promoting skin repair.

[0262] d) Safety: All examples showed zero skin irritation, which demonstrated the safety and mildness of the formulations of the present invention.

[0263] e) Antioxidant activity: The examples exhibited strong antioxidant capacity, and the IC50 value was significantly lower than that of the comparative example, indicating that the present invention has excellent free radical scavenging ability.

[0264] 3. Unexpected technical effects:

[0265] a) Synergistic effect: The combination of calendula seed oil and citronella oil (Example) is not only better than the single use in mosquito repellent effect (Comparative Examples 3 and 4), but also shows unexpected synergistic effects in other aspects such as soothing and anti-oxidation. This may be due to the mutual promotion of the active ingredients in the two essential oils at the molecular level.

[0266] b) Multifunctionality: The present invention not only achieves the expected mosquito repellent effect, but also performs well in soothing, repairing and anti-oxidation. This multifunctionality is not available in single-function products (such as Comparative Examples 1-4), providing users with a comprehensive outdoor skin protection solution.

[0267] c) Long-lasting protection: The mosquito repellent effect lasted longer than expected, and the repellency rate remained high after 8 hours. This may be because the plant extracts in the formula formed a sustained release system, which prolonged the action time of the active ingredients.

[0268] d) Biocompatibility: Zero irritation and excellent repair effect show that the present invention not only does not cause harm to the skin, but also actively promotes skin health. This biocompatibility far exceeds that of traditional mosquito repellent products, providing a safe and effective choice for users with sensitive skin.

[0269] e) Antioxidant-repair linkage effect: There may be a potential connection between strong antioxidant activity and excellent repair effect. The effective removal of free radicals may create a favorable environment for cell repair, thereby accelerating the repair process. This linkage effect is an important discovery of the present invention.

[0270] The invention achieves multiple functions of mosquito repelling, soothing, repairing and anti-oxidation through a carefully designed natural ingredient formula, while ensuring the safety of the product. The experimental results not only verified the expected effects, but also revealed multiple unexpected synergies and functional linkages, reflecting the innovation and superiority of the invention. This comprehensive skin protection solution provides a safer and more effective option for outdoor activities and has broad application prospects.

[0271] The above description is only an embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent substitution, improvement, etc. made within the spirit and principle of the present invention should be included in the scope of the claims of the present invention.

Claims

1. A composition having mosquito repelling, soothing and after-sun repairing effects, characterized in that: The composition comprises the following components by weight: 75.0-90.0 parts of water; 3.0-7.0 parts of methyl propanediol; 3.0-7.0 parts of balsam oil; 2.0-6.0 parts of menthol; 0.3-0.7 parts of sorbitan olivate; 0.3-0.7 parts of cetearyl glucoside; 0.3-0.7 parts of 1,2-hexanediol; 0.3-0.7 parts of citronella oil; 0. 2-0.6 parts; Capparis spinosa fruit extract 0.03-0.07 parts; Opuntia ficus-indica stem extract 0.02-0.05 parts; Olive leaf extract 0.03-0.06 parts; Maltodextrin 0.08-0.15 parts; Trehalose 0.08-0.12 parts; Carbomer 0.08-0.12 parts; Triethanolamine 0.08-0.12 parts; Ethylhexylglycerin 0.08-0.12 parts; The karela oleifera seed oil has the following characteristics: light yellow to yellowish brown oily liquid in appearance; density at 25°C of 0.90-0.93 g / cm³; refractive index at 25°C of 1.460-1.470; acid value ≤5.0 mg KOH / g; iodine value of 60-75 g I2 / 100g; The citronella oil has the following characteristics: light yellow to yellow transparent liquid; relative density at 20°C is 0.880-0.900; refractive index at 20°C is 1.470-1.490; optical rotation is -5° to +2°; citral content is ≥75%; The total flavonoids content of the Capparis spinosa fruit extract is ≥5% in terms of rutin; the total polysaccharide content of the Opuntia ficus-indica stem extract is ≥30%; the total phenol content of the Olea europaea leaf extract is ≥15% in terms of hydroxytyrosol; The preparation method of the composition comprises the following steps: step (1), preparing an oil phase: mixing olea europaea seed oil, citronella oil, sorbitan olivate and cetearyl glucoside, and stirring at 40-50°C at a speed of 200-300 rpm for 15-20 minutes; step (2), preparing an aqueous phase: mixing half of purified water with carbomer, stirring at a speed of 300-400 rpm for 10-15 minutes at room temperature, then adding methyl propanediol, 1,2-hexanediol and trehalose, and continuing to stir for 5-10 minutes; step (3), emulsifying: slowly adding the oil phase into the aqueous phase at 40-50°C, and stirring at a speed of 400-600 rpm for 15-20 minutes. ; Step (4), adding active ingredients: at 45-55°C, add menthol, caper fruit extract, peach cactus stem extract and olive leaf extract in sequence, stir for 2-3 minutes after each addition of an ingredient, then add the remaining purified water and stir for 5-10 minutes; Step (5), pH adjustment and preservation: at 35-40°C, add triethanolamine to adjust the pH to 6.5-7.5, then add phenoxyethanol and ethylhexylglycerin, and stir for 5-10 minutes; Step (6), homogenization and cooling: use a high shear homogenizer to homogenize at 5000-8000 rpm for 10-15 minutes, then slowly cool to room temperature, during which time maintain a low speed stirring of 100-200 rpm.

2. The composition according to claim 1, characterized in that In the step (1), the preparation temperature of the oil phase is 45-48°C, the stirring speed is 250-280 rpm, and the stirring time is 17-18 minutes.

3. The composition according to claim 1, characterized in that In the step (2), the preparation of the aqueous phase is carried out at 22-24° C., the dispersion stirring speed of the carbomer is 350-380 rpm, and the stirring time is 12-13 minutes.

4. The composition according to claim 1, characterized in that In the step (3), the temperature of the emulsification process is 46-48°C, the stirring speed is 500-550rpm, and the stirring time is 17-18 minutes.

5. The composition according to claim 1, characterized in that In the step (4), the adding temperature of the active ingredient is 48-52° C., and the stirring time of each active ingredient is 2.5-3 minutes.

6. The composition according to claim 1, characterized in that In the step (6), the rotation speed of the homogenization process is 6500-7500 rpm, the homogenization time is 12-13 minutes, and the stirring speed during the cooling process is 150-180 rpm.

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