Tea bag for preventing and relieving respiratory virus infection

Abstract

The invention provides a tea bag for preventing and relieving respiratory virus infection, and relates to the technical field of tea bags, a preparation method of the tea bag comprises the following steps: (1) respectively weighing 1-4 parts by mass of houttuynia cordata, 1-3 parts by mass of honeysuckle, 2-4 parts by mass of mint, 2-5 parts by mass of agastache rugosus and 1-2 parts by mass of liquorice, and respectively dehydrating and drying to obtain tea bags; crushing into particles smaller than 10 meshes; (2) mixing the crushed herba houttuyniae and liquorice, performing screw heating through a screw extruder, and extruding to obtain a puffed raw material; heating the puffed raw material to obtain a heating product, and performing fermentation and alcohol extraction to obtain micro powder A; (3) mixing the crushed honeysuckle flower, mint and wrinkled gianthyssop herb, and carrying out enzymolysis, fermentation and enzymolysis to obtain micro powder B; and (4) uniformly mixing the micro powder A and the micro powder B, subpackaging into tea bag paper bags, and then performing irradiation sterilization to obtain the tea bags. The teabag disclosed by the invention has the effects of preventing and relieving respiratory virus infection.

Description

Technical Field

[0001] The invention belongs to the technical field of tea bags, and in particular relates to a tea bag used for preventing and alleviating respiratory viral infection. Background Art

[0003] Respiratory viral infections are common illnesses caused by a variety of viruses and typically include the common cold, flu, etc. These infections primarily affect the respiratory system and symptoms may include cough, sore throat, nasal congestion, runny nose, fever, and body aches. For most healthy people, respiratory viral infections are self-limiting, however, for certain high-risk groups (such as the elderly, infants, and people with compromised immune systems), these infections may cause more serious complications, such as pneumonia.

[0004] The current prevention methods are mostly health and epidemic prevention, but due to the wide range of pathogens of respiratory viral infection, there is still a lack of clear and effective vaccines for prevention. Medicinal tea is a special liquid beverage with certain effects made by adding food or medicinal tea to tea. After the combination of tea and medicine, it can not only be used as a thirst-quenching drink for men, women, young and old in all seasons, but also can be used for fitness and treatment. However, the current medicinal tea is mostly soaked in hot water after mixing tea and raw materials, with poor leaching effect, and some water-insoluble ingredients cannot exert their efficacy.

[0005] Therefore, there is an urgent need for a tea bag for preventing and alleviating respiratory viral infections. Summary of the invention

[0006] The purpose of the invention is to provide a tea bag for preventing and alleviating respiratory virus infection.

[0007] In order to achieve the above object, the present invention provides the following technical solutions: A tea bag for preventing and alleviating respiratory viral infection, the preparation method of the tea bag comprising the following steps: (1) Weigh 1-4 parts by weight of Houttuynia cordata, 1-3 parts by weight of Honeysuckle, 2-4 parts by weight of Menthus officinalis, 2-5 parts by weight of Patchouli, and 1-2 parts by weight of Licorice, dehydrate and dry them respectively, and grind them into particles smaller than 10 mesh; (2) Mix the crushed Houttuynia cordata and Licorice, and pass through a screw extruder to heat the screw and extrude to obtain an expanded raw material; add 60-70 parts by weight of water to the expanded raw material, stir and heat for 40-45 minutes, cool to 35-40° C. to obtain a heated product, add composite bacteria A, perform anaerobic fermentation at 35-40° C. for 5-8 hours, sterilize, and obtain a fermentation product A; add 50-55 parts of ethanol to the fermentation product A, heat and reflux for extraction for 1.5-2 hours, extract 2-3 times, obtain an extracted product, and vacuum concentrate and dry the extracted product to obtain micropowder A; (3) Mix the crushed honeysuckle, mint and patchouli, add 40-45 parts by weight of water to obtain a mixed raw material, continue to add cellulase, perform enzymolysis at 30-35° C. for 1-3 days, inactivate the enzyme, and obtain a cellulase enzymolysis product, continue to add composite bacteria B, perform anaerobic fermentation at 35-40° C. for 10-12 days, and sterilize to obtain a fermentation product B; add bromelain to the fermentation product, perform enzymolysis at 30-35° C. for 3-5 days, inactivate the enzyme, and obtain a bromelain enzymolysis product; vacuum concentrate and dry the bromelain enzymolysis product to obtain micro powder B; (4) The micro powder A and the micro powder B are mixed evenly, and the mixture is packed into tea bag paper bags, and then irradiated and sterilized to obtain tea bags.

[0008] The houttuynia cordata in the prescription has inhibitory effects on herpes simplex virus (HSV), influenza A virus H1N1 and other viruses; honeysuckle can effectively alleviate the clinical symptoms of COVID-19 and inhibit the replication of SARS-COV-2, and has inhibitory effects on a variety of viruses, including avian influenza virus, influenza A virus, influenza virus, etc.; mint has inhibitory effects on HSV, H3N1 / H1N1, mumps and other viruses; patchouli has a good inhibitory effect on viruses such as H1N1 and H2N2; licorice can inhibit the replication of different enveloped viruses in vitro, including coronaviruses, and plays a role in harmonizing the medicinal properties in the prescription.

[0009] Houttuynia cordata is pungent and slightly cold, and enters the lung meridian; honeysuckle is sweet and cold, and enters the lung, stomach, and large intestine meridians; mint is pungent and cool, and enters the liver and lung meridians; patchouli is pungent and slightly warm, and enters the spleen, stomach, and lung meridians; licorice is sweet and neutral, and enters the heart, lung, spleen, and stomach meridians. In the prescription, houttuynia cordata, honeysuckle, and mint are cold in nature, patchouli is slightly warm, and licorice is neutral, so the whole prescription is balanced in nature, and the five medicinal and edible Chinese medicines all enter the lung meridian, and together they play a preventive and health-care role in lung diseases.

[0010] The prescription contains relatively high levels of mint and patchouli volatile oils. Mint volatile oil has a cool and transparent feeling, while patchouli volatile oil has a unique aromatic taste. Houttuynia cordata and honeysuckle both contain a small amount of volatile oil. Houttuynia cordata has a unique fishy smell, while honeysuckle has a bitter taste. Licorice is sweet, especially the aftertaste.

[0011] The present invention selects houttuynia cordata, honeysuckle, mint, patchouli and liquorice to prepare tea bags for preventing and alleviating respiratory viral infections. The effect of mixing raw materials and soaking them in hot water is not ideal. The present invention uses houttuynia cordata and liquorice as a group, and honeysuckle, mint and patchouli as a group, respectively using different methods for extraction, and the prepared tea bags have better effects of preventing and alleviating respiratory viruses.

[0012] In the process of preparing micro powder A, the present invention first uses a screw extruder to heat and expand Houttuynia cordata and licorice, and then uses composite bacteria A to ferment Houttuynia cordata and licorice, which has a better effect on preventing respiratory viruses. Analysis shows that Houttuynia cordata and licorice after heating and expansion help release more bioactive ingredients, and then continue to use Houttuynia cordata and licorice fermented by specific strains. The obtained micro powder A contains more active components, has high immunity, antioxidant and anti-inflammatory effects to enhance the body's resistance and reduce the chance of virus invasion. However, the effect of relieving respiratory viruses under this condition is limited.

[0013] Furthermore, the composite bacteria A includes Bifidobacterium animalis, Lactobacillus plantarum and Lactobacillus casei.

[0014] Furthermore, the concentration of animal Bifidobacterium in the heated product is 10 6 -10 7 CFU / mL; the concentration of Lactobacillus plantarum in the heated product is 10 8 -10 9 CFU / mL; the concentration of Lactobacillus casei in the heated product is 10 10 -10 11 CFU / mL.

[0015] Furthermore, the composite bacteria B includes Bifidobacterium bifidum, Bifidobacterium lactis and Lactobacillus bulgaricus.

[0016] Furthermore, the concentration of Bifidobacterium bifidum in the cellulase hydrolysate is 10 6 -10 7 CFU / mL; the concentration of Bifidobacterium lactis in the cellulase hydrolysate was 10 8 -10 9 CFU / mL; the concentration of Lactobacillus bulgaricus in the cellulase hydrolysate was 10 10 -10 11 CFU / mL.

[0017] Furthermore, the amount of cellulase in the mixed raw material is 60U / mL-80U / mL.

[0018] Furthermore, the amount of bromelain in the fermentation product is 100U / mL-120U / mL.

[0019] In order to improve the effect of teabags on relieving respiratory viruses, the present invention first enzymolyzes honeysuckle, mint, and patchouli with cellulase, then ferments with composite bacteria B, and finally enzymolyzes with bromelain, and the obtained micropowder B can improve the effect of teabags on relieving respiratory viruses. Analysis shows that the active components in the micropowder B prepared under this condition have antiviral effects when relieving respiratory viral infections, can directly inhibit the replication and spread of viruses, and the active components can help alleviate the discomfort caused by the disease through the antiviral effects, immunomodulatory effects, and symptom relief effects of teabags.

[0020] Furthermore, the four-stage temperature gradient of the screw heating is 80-90°C, 110-120°C, 140-150°C, and 170-180°C.

[0021] Furthermore, the stirring and heating conditions in step (2) are: under the conditions of steam pressure of 0.2-0.4 MPa and temperature of 125-130°C.

[0022] Furthermore, 2 parts by mass of Houttuynia cordata, 2 parts by mass of Honeysuckle, 2 parts by mass of Menthus fragrans, 3 parts by mass of Patchouli, and 2 parts by mass of Licorice were weighed respectively.

[0023] Tea bags made of Houttuynia cordata, honeysuckle, mint, patchouli and licorice (3g per bag) can play a certain health-care role in preventing and relieving respiratory viral infections. On this basis, you can add white tea or rock sugar according to your personal taste, which can balance yin and yang and regulate the body's qi.

[0024] Compared with the prior art, the advantages and beneficial effects of the present invention are: 1. The present invention takes Houttuynia cordata and Licorice as one group, and honeysuckle, mint and Patchouli as one group, and uses different methods to extract them respectively, so that the prepared tea bags have better effects on preventing and alleviating respiratory viruses.

[0025] 2. When compound bacteria A is used to ferment Houttuynia cordata and licorice, the effect of preventing respiratory viruses is better.

[0026] 3. In the present invention, honeysuckle, mint and patchouli are first enzymolyzed with cellulase, then fermented with composite bacteria B, and finally enzymolyzed with bromelain. The obtained micropowder B can improve the effect of teabags on relieving respiratory viruses. DETAILED DESCRIPTION

[0027] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0028] Bifidobacterium animalis, accession number: SHBCCD24407AS1.1852, was purchased from China Center for Type Culture Collection.

[0029] Lactobacillus plantarum, accession number: CCTCCAB2010210, was purchased from China Center for Type Culture Collection.

[0030] Lactobacillus casei, accession number: SHBCCD24737, was purchased from Shanghai Microbiological Collection Center.

[0031] Bifidobacterium bifidum, accession number: SHBCCD24408ATCC35914, was purchased from Shanghai Microbiological Collection Center.

[0032] Bifidobacterium lactis, accession number: SHBCCD24675, was purchased from Shanghai Microbiological Collection Center.

[0033] Lactobacillus bulgaricus, accession number: CCTCCCB20082295; purchased from China Center for Type Culture Collection.

[0034] Example 1 This embodiment provides a tea bag for preventing and alleviating respiratory viral infection. The preparation method of the tea bag comprises the following steps: (1) Weigh 2 parts by weight of Houttuynia cordata, 2 parts by weight of Honeysuckle, 2 parts by weight of Menthus officinalis, 3 parts by weight of Patchouli, and 2 parts by weight of Licorice, dehydrate and dry them respectively, and grind them into particles smaller than 10 mesh; (2) Mix the crushed Houttuynia cordata and licorice, and pass through a screw extruder to perform screw heating. The four-stage temperature gradient of the screw heating is 85°C, 115°C, 145°C, and 175°C. Extrude to obtain a puffed raw material; add 65 parts by mass of water to the puffed raw material, stir and heat for 42 minutes. The stirring and heating conditions are: steam pressure 0.3MPa, temperature 128°C; cool to 37°C to obtain a heated product, and add composite bacteria A. The composite bacteria A includes animal Bifidobacterium, plant Lactobacillus, and casei. The concentration of animal Bifidobacterium in the heated product is 10 6 CFU / mL heated product; the concentration of Lactobacillus plantarum in the heated product was 10 9 CFU / mL heated product; the concentration of Lactobacillus casei in the heated product was 10 10 CFU / mL heating product. Anaerobic fermentation was carried out at 38°C for 6 hours, and sterilized to obtain fermentation product A; 52 parts of ethanol were added to fermentation product A, and the mixture was heated under reflux for 1.7 hours, and extracted 3 times to obtain an extract product, and the extract product was vacuum concentrated and dried to obtain micro powder A; (3) Mix the crushed honeysuckle, mint and patchouli, add 43 parts by weight of water to obtain a mixed raw material, continue to add cellulase, the amount of cellulase in the mixed raw material is 70U / mL mixed raw material, perform enzymolysis at 32°C for 2 days, after inactivating the enzyme, obtain a cellulase hydrolysis product, continue to add composite bacteria B, the composite bacteria B includes Bifidobacterium bifidum, Bifidobacterium lactis and Lactobacillus bulgaricus. The concentration of Bifidobacterium bifidum in the cellulase hydrolysis product is 10 7 CFU / mL cellulase hydrolyzate; the amount of Bifidobacterium lactis in the cellulase hydrolyzate was 10 8 CFU / mL cellulose enzymatic hydrolysate; the amount of Lactobacillus bulgaricus in the cellulose enzymatic hydrolysate was 10 11 CFU / mL cellulase hydrolysis product; performing anaerobic fermentation at 37°C for 11 days, and sterilizing to obtain fermentation product B; adding bromelain to the fermentation product, wherein the amount of bromelain in the fermentation product B is 110U / mL fermentation product B, performing enzymolysis at 32°C for 4 days, and inactivating the enzyme to obtain bromelain hydrolysis product; vacuum concentrating and drying the bromelain hydrolysis product to obtain micro powder B; (4) The micro powder A and the micro powder B are mixed evenly, and the mixture is packed into tea bag paper bags, and then irradiated and sterilized to obtain tea bags.

[0035] Example 2 This embodiment provides a tea bag for preventing and alleviating respiratory viral infection. The preparation method of the tea bag comprises the following steps: (1) Weigh 2 parts by weight of Houttuynia cordata, 2 parts by weight of Honeysuckle, 2 parts by weight of Menthus officinalis, 3 parts by weight of Patchouli, and 2 parts by weight of Licorice, dehydrate and dry them respectively, and grind them into particles smaller than 10 mesh; (2) Mix the crushed Houttuynia cordata and licorice, and pass through a screw extruder to perform screw heating. The four-stage temperature gradient of the screw heating is 80°C, 120°C, 140°C, and 180°C. Extrude to obtain a puffed raw material; add 60 parts by mass of water to the puffed raw material, stir and heat for 45 minutes. The stirring and heating conditions are: under a steam pressure of 0.2 MPa and a temperature of 130°C; cool to 35°C to obtain a heated product, and add composite bacteria A. The composite bacteria A includes animal bifidobacterium, plant lactobacillus, and casei. The amount of animal bifidobacterium in the heated product is 10 7 CFU / mL; the amount of Lactobacillus plantarum in the heated product is 10 8 CFU / mL; the amount of Lactobacillus casei in the heated product is 10 11CFU / mL. Anaerobic fermentation was carried out at 35°C for 8 hours, followed by sterilization to obtain fermentation product A; 50 parts of ethanol were added to the fermentation product A, and the mixture was heated under reflux for extraction for 2 hours, and the extraction was repeated twice to obtain an extract product, and the extract product was vacuum concentrated and dried to obtain micro powder A; (3) Mix the crushed honeysuckle, mint and patchouli, add 45 parts by weight of water to obtain a mixed raw material, continue to add cellulase, the amount of cellulase in the mixed raw material is 60U / mL, perform enzymolysis at 35°C for 1 day, after inactivating the enzyme, obtain a cellulase hydrolysis product, continue to add composite bacteria B, the composite bacteria B includes Bifidobacterium bifidum, Bifidobacterium lactis and Lactobacillus bulgaricus. The concentration of Bifidobacterium bifidum in the cellulase hydrolysis product is 10 7 CFU / mL; the concentration of Bifidobacterium lactis in the cellulase hydrolysate was 10 8 CFU / mL; the concentration of Lactobacillus bulgaricus in the cellulase hydrolysate was 10 11 CFU / mL; performing anaerobic fermentation at 35°C for 12 days, sterilizing, and obtaining a fermentation product B; adding bromelain to the fermentation product, wherein the amount of bromelain in the fermentation product B is 100U / mL, performing enzymolysis at 35°C for 3 days, inactivating the enzyme, obtaining a bromelain enzymolysis product, and vacuum concentrating and drying the bromelain enzymolysis product to obtain micro powder B; (4) The micro powder A and the micro powder B are mixed evenly, and the mixture is packed into tea bag paper bags, and then irradiated and sterilized to obtain tea bags.

[0036] Example 3

[0037] This embodiment provides a tea bag for preventing and alleviating respiratory viral infection. The preparation method of the tea bag comprises the following steps: (1) Weigh 2 parts by weight of Houttuynia cordata, 2 parts by weight of Honeysuckle, 2 parts by weight of Menthus officinalis, 3 parts by weight of Patchouli, and 2 parts by weight of Licorice, dehydrate and dry them respectively, and grind them into particles smaller than 10 mesh; (2) Mix the crushed Houttuynia cordata and licorice, and pass through a screw extruder to perform screw heating. The four-stage temperature gradient of the screw heating is 90°C, 110°C, 150°C, and 170°C. Extrude to obtain a puffed raw material; add 70 parts by weight of water to the puffed raw material, stir and heat for 40 minutes. The stirring and heating conditions are: under a steam pressure of 0.4 MPa and a temperature of 125°C; cool to 40°C to obtain a heated product, and add composite bacteria A. The composite bacteria A includes animal bifidobacterium, plant lactobacillus, and casei. The amount of animal bifidobacterium in the heated product is 10 6 CFU / mL; the amount of Lactobacillus plantarum in the heated product is 10 9 CFU / mL; the amount of Lactobacillus casei in the heated product is 10 10CFU / mL. Anaerobic fermentation was carried out at 40°C for 5 hours, followed by sterilization to obtain fermentation product A; 55 parts of ethanol were added to the fermentation product A, and the mixture was heated under reflux for extraction for 1.5 hours, and the extraction was repeated 3 times to obtain an extract product, and the extract product was vacuum concentrated and dried to obtain micro powder A; (3) Mix the crushed honeysuckle, mint and patchouli, add 45 parts by weight of water to obtain a mixed raw material, continue to add cellulase, the amount of cellulase in the mixed raw material is 80 U / mL, perform enzymolysis at 30°C for 3 days, after enzyme inactivation, obtain a cellulase hydrolysis product, continue to add composite bacteria B, the composite bacteria B includes Bifidobacterium bifidum, Bifidobacterium lactis and Lactobacillus bulgaricus. The amount of Bifidobacterium bifidum in the cellulase hydrolysis product is 10 6 CFU / mL; the amount of Bifidobacterium lactis in the cellulase hydrolysate was 10 9 CFU / mL; the amount of Lactobacillus bulgaricus in the cellulase hydrolysate was 10 10 CFU / mL; performing anaerobic fermentation at 40°C for 10 days, sterilizing, and obtaining a fermentation product B; adding bromelain to the fermentation product, wherein the amount of bromelain in the fermentation product B is 120U / mL, performing enzymolysis at 30°C for 5 days, inactivating the enzyme, obtaining a bromelain enzymolysis product, and vacuum concentrating and drying the bromelain enzymolysis product to obtain micro powder B; (4) The micro powder A and the micro powder B are mixed evenly, and the mixture is packed into tea bag paper bags, and then irradiated and sterilized to obtain tea bags.

[0038] Comparative Example 1 The difference between this comparative example and Example 1 is that 0.5 parts by mass of Houttuynia cordata, 3.5 parts by mass of Honeysuckle, 1 part by mass of Menthus officinalis, 1 part by mass of Patchouli, and 4 parts by mass of Licorice are weighed respectively.

[0039] Comparative Example 2 The difference between this comparative example and Example 1 is as follows: the crushed Houttuynia cordata and licorice are mixed to obtain a mixed raw material; 65 parts by weight of water are added to the mixed raw material, and the mixture is stirred and heated for 42 minutes under the conditions of steam pressure of 0.3 MPa and temperature of 128°C; the mixture is cooled to 37°C to obtain a heated product, and composite bacteria A is added, wherein the composite bacteria A includes animal bifidobacterium, plant lactobacillus and casei lactobacillus. The amount of animal bifidobacterium in the heated product is 10 6 CFU / mL; the amount of Lactobacillus plantarum in the heated product is 10 9 CFU / mL; the amount of Lactobacillus casei in the heated product is 10 10CFU / mL. Anaerobic fermentation was carried out at 38°C for 6 hours, followed by sterilization to obtain fermentation product A; 52 parts of ethanol were added to the fermentation product A, and the product was heated under reflux for extraction for 1.7 hours, and the extraction was repeated 3 times to obtain an extract product, and the extract product was vacuum concentrated and dried to obtain micro powder A.

[0040] Comparative Example 3 The difference between this comparative example and Example 1 is that the composite bacteria A includes Bifidobacterium bifidum, Bifidobacterium lactis and Lactobacillus bulgaricus. The amount of Bifidobacterium bifidum used in the heated product is 10 6 CFU / mL; the amount of Bifidobacterium lactis in the heated product is 10 9 CFU / mL; the amount of Lactobacillus bulgaricus in the heated product is 10 10 CFU / mL.

[0041] Comparative Example 4 The difference between this comparative example and Example 1 is that the amount of animal Bifidobacterium used in the heated product is 10 10 CFU / mL; the amount of Lactobacillus plantarum in the heated product is 10 6 CFU / mL; the amount of Lactobacillus casei in the heated product is 10 9 CFU / mL.

[0042] Comparative Example 5 The difference between this comparative example and Example 1 is that cellulase is replaced by pectinase; bromelain is replaced by chitosanase.

[0043] Comparative Example 6 The difference between this comparative example and Example 1 is that the composite bacteria B includes animal Bifidobacterium, plant Lactobacillus and casei Lactobacillus; the amount of animal Bifidobacterium in the cellulase hydrolyzate is 10 7 CFU / mL; the amount of Lactobacillus plantarum in the cellulase hydrolysate was 10 8 CFU / mL; the amount of Lactobacillus casei in the cellulase hydrolysate was 10 11 CFU / mL.

[0044] Comparative Example 7 The difference between this comparative example and Example 1 is that the amount of Bifidobacterium bifidum used in the cellulase hydrolyzate is 10 7 CFU / mL; the amount of Bifidobacterium lactis in the cellulase hydrolysate was 10 8 CFU / mL; the amount of Lactobacillus bulgaricus in the cellulase hydrolysate was 10 11 CFU / mL.

[0045] Comparative Example 8 The difference between this comparative example and Example 1 is: a tea bag for preventing and relieving respiratory viral infections, and the preparation method of the tea bag is: weigh 2 parts by mass of Houttuynia cordata, 2 parts by mass of Honeysuckle, 2 parts by mass of Menthus officinalis, 3 parts by mass of Patchouli, and 2 parts by mass of Licorice, dehydrate and dry them respectively, and crush them into particles smaller than 10 mesh; mix them evenly, pack them into tea bag paper bags, and then sterilize them by irradiation to obtain tea bags.

[0046] Performance Testing How to drink: Take 1 tea bag, open the bag, pour it into a cup, add 200 ml of hot water above 85℃, brew for 10 minutes, and then drink. Drink at least 800 ml of water for each tea bag.

[0047] The tea bags of Examples 1-3 and Comparative Examples 1-8 were tested for performance, as follows: 1. Experiments on prevention of respiratory viruses A total of 240 healthy subjects were randomly selected as samples, with half male and half female, ranging in age from 15 to 80 years old, and an average age of 45.16±20.29 years old. They were divided into 12 groups, with 20 subjects in each group.

[0048] The subjects were divided into an observation group and a control group, wherein the observation group took the tea bags of Examples 1-3 of the present invention and Comparative Examples 1-8, twice a day, one bag at a time, 3 g per bag, for 3 consecutive months. The control group did not take any product. The upper respiratory tract infection conditions of the observation group and the control group within 3 months were observed and recorded.

[0049] 2. Experiments to alleviate respiratory viruses 600 patients with lung discomfort due to respiratory viral infection were selected, and all patients were between 20 and 60 years old. The patients mainly showed symptoms of cough with sputum, chest tightness, shortness of breath, and difficulty breathing. During the trial, all patients stopped taking other drugs and health products and lived a normal life. Every 50 patients were divided into a group, and took the tea bags of Examples 1-3 and Comparative Examples 1-8, twice a day, one bag at a time, 3g per bag, and the number of people with different symptoms after taking it for two weeks was counted. The control group did not take any product.

[0050] Significant improvement: Breathing is smooth; chest tightness and shortness of breath are significantly reduced; cough frequency is reduced to less than 1 / 3 of the original frequency; sputum volume is reduced to less than 1 / 3 of the original frequency; Improved to a certain extent: Breathing is smoother; chest tightness and shortness of breath are relieved; cough frequency is reduced to 1 / 3~1 / 2 of the original frequency; sputum volume is reduced to 1 / 3~1 / 2 of the original sputum volume; No effect: breathing is still not smooth; chest tightness and shortness of breath; coughing frequency is reduced to more than 1 / 2 of the original frequency; the amount of sputum is reduced to more than 1 / 2 of the original amount of sputum.

[0051] The results of the effect test are shown in Table 1.

[0052] Table 1 Effect test

[0053] It can be seen from the above performance test results that the tea bags of Examples 1-3 are effective in preventing and alleviating respiratory viral infections, especially the comprehensive performance of Example 1 is the most outstanding. This is mainly because the content of effective components in the prepared tea bags is higher, resulting in a synergistic effect.

[0054] However, the comparative examples did not adopt the necessary technical solutions, resulting in that they were significantly worse than the embodiments in the corresponding performance tests. In comparative example 1, the ratio of raw materials was changed, and it can be seen that the comprehensive effect of the tea bag decreased, proving that the ratio of raw materials used has an important influence on the product effect. In comparative examples 2-4, the preparation method of micropowder A was changed, and the effect on preventing respiratory viral infections decreased. In comparative examples 5-7, the preparation method of micropowder B was changed, and the effect on alleviating respiratory viral infections decreased. Comparative example 8 used a commonly used method on the market to prepare tea bags, and the effect was worse than the tea bags prepared by the present invention. The above experimental results further prove the importance of the technical solution defined in the present invention for its technical effects.

[0055] The above is a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A tea bag for preventing and alleviating respiratory viral infections, characterized in that: The preparation method of the tea bag comprises the following steps: (1) Weigh 1-4 parts by weight of Houttuynia cordata, 1-3 parts by weight of Honeysuckle, 2-4 parts by weight of Menthus officinalis, 2-5 parts by weight of Patchouli, and 1-2 parts by weight of Licorice, dehydrate and dry them respectively, and grind them into particles smaller than 10 mesh; (2) Mix the crushed Houttuynia cordata and Licorice, and pass through a screw extruder to heat the screw and extrude to obtain an expanded raw material; add 60-70 parts by weight of water to the expanded raw material, stir and heat for 40-45 minutes, cool to 35-40° C. to obtain a heated product, add composite bacteria A, perform anaerobic fermentation at 35-40° C. for 5-8 hours, sterilize, and obtain a fermentation product A; add 50-55 parts of ethanol to the fermentation product A, heat and reflux for extraction for 1.5-2 hours, extract 2-3 times, obtain an extracted product, and vacuum concentrate and dry the extracted product to obtain micropowder A; (3) Mix the crushed honeysuckle, mint and patchouli, add 40-45 parts by weight of water to obtain a mixed raw material, continue to add cellulase, perform enzymolysis at 30-35° C. for 1-3 days, inactivate the enzyme, and obtain a cellulase enzymolysis product, continue to add composite bacteria B, perform anaerobic fermentation at 35-40° C. for 10-12 days, and sterilize to obtain a fermentation product B; add bromelain to the fermentation product, perform enzymolysis at 30-35° C. for 3-5 days, inactivate the enzyme, and obtain a bromelain enzymolysis product; vacuum concentrate and dry the bromelain enzymolysis product to obtain micro powder B; (4) The micro powder A and the micro powder B are mixed evenly, and the mixture is packed into tea bag paper bags, and then irradiated and sterilized to obtain tea bags.

2. The tea bag for preventing and alleviating respiratory viral infection according to claim 1, characterized in that: Composite bacteria A includes Bifidobacterium animalis, Lactobacillus plantarum and Lactobacillus casei.

3. The tea bag for preventing and alleviating respiratory viral infection according to claim 2, characterized in that: The amount of animal bifidobacterium used in the heated product is 10 6 -10 7 CFU / mL; the amount of Lactobacillus plantarum in the heated product is 10 8 -10 9 CFU / mL; the amount of Lactobacillus casei in the heated product is 10 10 -10 11 CFU / mL.

4. The tea bag for preventing and alleviating respiratory viral infection according to claim 1, characterized in that: Complex B bacteria include Bifidobacterium bifidum, Bifidobacterium lactis and Lactobacillus bulgaricus.

5. The tea bag for preventing and alleviating respiratory viral infection according to claim 4, characterized in that: The amount of Bifidobacterium bifidum in the cellulase hydrolyzate is 10 6 -10 7 CFU / mL; the amount of Bifidobacterium lactis in the cellulase hydrolysate was 10 8 -10 9 CFU / mL; the amount of Lactobacillus bulgaricus in the cellulase hydrolysate was 10 10 -10 11 CFU / mL.

6. The tea bag for preventing and alleviating respiratory viral infection according to claim 1, characterized in that: The amount of cellulase used in the mixed raw material is 60U / mL-80U / mL.

7. The tea bag for preventing and alleviating respiratory viral infection according to claim 1, characterized in that: The amount of bromelain used in the fermentation product is 100U / mL-120U / mL.

8. The tea bag for preventing and alleviating respiratory viral infection according to claim 1, characterized in that: The four-stage temperature gradient of screw heating is 80-90℃, 110-120℃, 140-150℃, and 170-180℃.

9. The tea bag for preventing and alleviating respiratory viral infection according to claim 1, characterized in that: The stirring and heating conditions in step (2) are: steam pressure of 0.2-0.4 MPa and temperature of 125-130°C.

10. The tea bag for preventing and alleviating respiratory viral infection according to claim 1, characterized in that: Weigh 2 parts by mass of Houttuynia cordata, 2 parts by mass of Honeysuckle, 2 parts by mass of Menthus fragrans, 3 parts by mass of Patchouli, and 2 parts by mass of Licorice.

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