Application of traditional Chinese medicine inunction prescription for nourishing liver and kidney as medicine for treating polymyalgia rheumatica

Abstract

The invention relates to an application of a traditional Chinese medicine inunction prescription for nourishing liver and kidney as a medicine for treating polymyalgia rheumatic, and belongs to the field of traditional Chinese medicine preparations for treating polymyalgia rheumatic. In the traditional Chinese medicine inunction prescription, polygonum cuspidatum, kalimeris indica root and ramulus mori are used as monarch drugs for dispelling wind, eliminating dampness and easing joint movement; the pedicularis and the radix angelicae have the effects of dispelling wind and relieving pain, enhancing local blood circulation and promoting drug absorption, the borneol, the gypsum and the nightshade assist the monarch drug to enhance the anti-inflammatory effect, and the discolor cinquefoil herb and the bulbus tulip bulb have the effects of clearing away heat and toxic materials and relieving swelling and pain and are all ministerial drugs; the manyleaf paris rhizome and the artemisia anomala are used for assisting the monarch drugs to dissipate blood stasis, relieve pain and promote blood circulation to subdue swelling, and the pepper, the croton and the far infrared ceramic powder are used for anesthesia, analgesia and enhancement of drug permeability and are used as adjuvant drugs; rhododendron molle and periploca forrestii schltr harmonize the medicines, enhance the overall curative effect and serve as conductant medicines together. Therefore, according to the traditional Chinese medicine inunction prescription provided by the invention, dialectical treatment is performed from the perspective of nourishing the liver and the kidney, and the treatment effect is relatively good.

Description

Technical Field

[0001] The invention belongs to the field of traditional Chinese medicine preparations for treating polymyalgia rheumatica, and specifically relates to the application of a traditional Chinese medicine rubbing prescription for nourishing the liver and kidney as a medicine for treating polymyalgia rheumatica. Background Art

[0002] Polymyalgia rheumatica (PMR) is an autoimmune disease with typical symptoms including pain and stiffness in the neck, shoulder girdle and pelvic girdle muscles, which may be accompanied by systemic symptoms such as increased erythrocyte sedimentation rate and fever. It is particularly prone to affect women aged 50 and above. In traditional Chinese medicine theory, polymyalgia rheumatica can be classified as "muscle paralysis" and "tendon paralysis". Its pathological basis is mainly attributed to the weakness of liver and kidney function, which is manifested as insufficient vital energy and obstructed circulation of qi, blood and body fluids, which in turn leads to the accumulation of damp heat, phlegm and blood stasis. These pathological products are deposited in muscles and joints throughout the body, causing tendon discomfort and skin pain. It is worth noting that polymyalgia rheumatica is common in perimenopausal women. Patients in this period are often accompanied by the physical characteristics of liver blood deficiency and kidney essence deficiency. The core manifestations of this disease - pain and stiffness - are closely related to the blocking of meridians by phlegm and blood stasis and the poor circulation of qi and blood, reflecting the pathological characteristics of "deficiency in the root and excess in the superficial symptoms" in traditional Chinese medicine. Summary of the invention

[0003] The object of the present invention is to provide a Chinese medicine rubbing prescription for nourishing liver and kidney as a therapeutic drug for rheumatic polymyalgia, the Chinese medicine rubbing prescription comprises Artemisia selengensis, Herba Lycopodii, Radix Achyranthis Bidentatae, Rhizoma Mori, Gypsum, Polygonum Cuspidati, Solanum nigrum, Rhizoma Cynomorii, Far Infrared Ceramic Powder, Herba Polygoni Multiflori, Angelicae Dahuricae, Borneolum Syntheticum, Zanthoxylum bungeana, Glehnia littoralis, Croton tiglium, and Rhizoma Achyranthis Bidentatae. The Chinese medicine rubbing prescription is dialectically treated from the perspective of nourishing liver and kidney, and has a good therapeutic effect.

[0004] The technical solution adopted by the present invention is:

[0005] A Chinese medicinal rubbing formula for nourishing the liver and kidneys is used as a drug for treating polymyalgia rheumatica, wherein the effective ingredients of the Chinese medicinal rubbing formula for nourishing the liver and kidneys are prepared from the following Chinese medicinal raw materials by weight:

[0006]

[0007] In the Chinese medicine rubbing prescription, the medicinal properties of each Chinese medicine raw material are as follows:

[0008] Pedicularis: bitter and cold, enters the kidney and bladder meridians, eliminates rheumatism, promotes diuresis and relieves stranguria, and attacks toxins and kills insects.

[0009] Herba Lycopodii: pungent and warm, enters the Liver Channel, is highly toxic, dispels wind and dampness, disperses blood stasis and relieves pain.

[0010] Malan root: pungent, neutral, enters the lung, liver, stomach, and large intestine meridians, cools blood and relieves pain, clears heat and removes dampness, detoxifies and reduces swelling.

[0011] Black bone vine: pungent, warm, enters the liver and kidney meridians, slightly toxic, dispels wind and dampness, relaxes muscles and promotes blood circulation, and has anti-inflammatory and detoxification effects.

[0012] Mulberry branch: bitter and flat in taste, enters the liver meridian, eliminates rheumatism and benefits joints.

[0013] Gypsum: pungent, sweet, and very cold. It enters the lung and stomach meridians. It absorbs dampness, promotes accumulation, heals sores, and stops bleeding.

[0014] Polygonum cuspidatum: bitter and cold, enters the liver, gallbladder and lung meridians, promotes bile secretion and reduces jaundice, clears away heat and detoxifies, disperses blood stasis and relieves pain, and relieves cough and resolves phlegm.

[0015] Solanum nigrum: bitter and cold, enters the liver and stomach meridians, clears away heat and detoxifies, reduces swelling and resolves nodules, and has anti-inflammatory and diuretic effects.

[0016] Radix Angelicae Pubescentis: bitter and cold, enters the Liver Channel, clears away heat and promotes blood circulation, detoxifies, strengthens the body, invigorates Qi and regulates the body.

[0017] Far-infrared ceramic powder: warms the meridians and dredges the collaterals, disperses nodules and relieves pain.

[0018] Herba Discoloris: sweet and bitter, neutral, enters the stomach and large intestine meridians, cools blood, detoxifies, stops bleeding and reduces swelling.

[0019] Angelica dahurica: pungent and warm, it enters the stomach, large intestine, and lung meridians. It can relieve exterior symptoms and dispel cold, dispel wind and relieve pain, dredge the nasal passages, dry up dampness and stop leukorrhea, and reduce swelling and discharge pus.

[0020] Borneol: pungent, bitter, slightly cold, enters the heart, spleen and lung meridians, opens the orifices and refreshes the mind, clears away heat and relieves pain.

[0021] Zanthoxylum bungeanum: spicy and warm, enters the spleen, stomach and kidney meridians, warms the middle and relieves pain, kills insects and relieves itching.

[0022] Glehnia littoralis: sweet, pungent, and cold, it enters the liver, stomach, and lung meridians, clears away heat and detoxifies, reduces swelling, and inhibits bacteria.

[0023] Croton: pungent and hot, enters the stomach and large intestine meridians, is highly toxic, can eliminate cold accumulation, expel water and reduce swelling, and relieve phlegm and sore throat.

[0024] Liu Jinu: bitter, warm, enters the heart, liver and spleen meridians, promotes blood circulation and menstruation, reduces swelling and relieves pain, and helps digestion and eliminates stagnation.

[0025] The root cause of polymyalgia rheumatica is insufficient vital energy, which comes from insufficient nourishment of kidney essence and acquired water and food. Liver and kidney essence and blood are interdependent, and liver blood nourishes tendons and makes them flexible. Women over 50 years old are prone to liver blood and kidney essence deficiency due to their physiological characteristics and physiological processes, which affects the generation of vital energy, causing muscle pain and joint stiffness. Blood deficiency and low fever are accompanied by onset, and insufficient vital energy can easily lead to dysfunction of internal organs, such as liver qi stagnation leading to emotional discomfort, and kidney qi deficiency leading to tinnitus and deafness. As the "Shengji Zonglu" says: "The liver stores blood and combines with tendons. When the liver qi is harmonious, the qi and blood are strong and flow through the fascia, so the bones are straight and the tendons are soft, and the qi and blood are all in harmony." Patients with polymyalgia rheumatica need to focus on nourishing the liver and kidneys and replenishing vital energy to improve tendon and bone pain and enhance body function. Through Chinese medicine conditioning, balancing the internal organs and restoring the circulation of qi and blood can help relieve PMR symptoms and improve the quality of life.

[0026] The Chinese medicine rubbing prescription for nourishing the liver and kidney proposed by the present invention uses Polygonum cuspidatum, Malan root and Morus alba as main medicines, which can dispel wind and dampness and open up joints; Artemisia selengensis and Angelica dahurica can dispel wind and relieve pain, enhance local blood circulation and promote drug absorption; Borneol, gypsum and Solanum nigrum assist the main medicines to strengthen the anti-inflammatory effect; Herba Polygoni Multiflori and Herba Cibotii clear away heat and detoxicate, relieve swelling and relieve pain, and are collectively ministerial medicines; Rhizoma Cynomorii and Herba Ligustici amara assist the main medicines to disperse blood stasis and relieve pain, activate blood circulation and relieve swelling; Zanthoxylum bungeanum, Croton tiglium and far-infrared ceramic powder can anesthetize and relieve pain, and enhance drug penetration, and are collectively adjuvant medicines; Herba Lycopodii and Herba Aconiti Lateralis can coordinate various medicines, enhance the overall therapeutic effect, and are collectively guide medicines.

[0027] As a preferred technical solution of the present invention, the effective ingredients of the Chinese medicine rubbing prescription for nourishing the liver and kidney are prepared from the following Chinese medicine raw materials by weight:

[0028]

[0029] The preparation method of the Chinese medicine rubbing prescription for nourishing the liver and kidneys has the following steps:

[0030] (1) First, wash and dry each Chinese herbal medicine component and weigh it according to the amount;

[0031] (2) Grind the 16 medicinal materials except the far-infrared ceramic powder into powder, add the far-infrared ceramic powder, and stir evenly;

[0032] (3) adding the above-mentioned finely ground raw materials to lotus paste, with the weight ratio of Chinese medicine powder to lotus paste being 3:1;

[0033] (4) The prepared ointment is spread on a piece of paper to prepare a Chinese medicine ointment for treating polymyalgia rheumatica. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 Changes of ESR levels in the three groups during treatment.

[0035] Figure 2 Changes of CRP levels in the three groups during treatment. DETAILED DESCRIPTION

[0036] The application of a Chinese medicinal rubbing prescription for nourishing the liver and kidney as a therapeutic drug for polymyalgia rheumatica of the present invention is further described in detail below in conjunction with the accompanying drawings and examples.

[0037] Example 1

[0038] A Chinese medicinal rubbing prescription for nourishing the liver and kidney as a therapeutic drug for rheumatic polymyalgia is prepared from the following Chinese medicinal raw materials by weight:

[0039] Pedicularis 5g, Wolfberry 3g, Malan root 15g, Acanthus sinensis 3g, Morus 15g, Gypsum 5g, Polygonum cuspidatum 15g, Solanum nigrum 10g, Folium solanum 5g, Far-infrared ceramic powder 5g, Herba Pogostemonis 10g, Angelica dahurica 10g, Borneolum 10g, Zanthoxylum bungeanum 10g, Cnidium monnieri 10g, Croton 3g, Achyranthes bidentata 10g.

[0040] The preparation steps are as follows:

[0041] (1) First, wash and dry each Chinese herbal medicine component and weigh it according to the amount;

[0042] (2) Grind the 16 medicinal materials except the far-infrared ceramic powder into powder, add the far-infrared ceramic powder, and stir evenly;

[0043] (3) adding the above-mentioned finely ground raw materials to lotus paste (purchased from the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine), with the weight ratio of Chinese medicine powder to lotus paste being 3:1;

[0044] (4) The prepared ointment is spread on a piece of paper to prepare a Chinese medicine ointment for treating polymyalgia rheumatica.

[0045] Example 2 Efficacy judgment and clinical observation data:

[0046] (1) The subjects strictly followed the experimental requirements: they maintained a normal life, did not engage in additional activities that might affect the experimental results, and did not receive any other treatment during the trial. Three groups of subjects (60 patients in each group) went to the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine 3 hours after lunch every day to receive massage (massage group), Chinese medicine application (application group), and Chinese medicine application plus far infrared intervention (application + FIR group), once a day, 25 min / time, for 4 consecutive weeks.

[0047] (2) Treatment method: In the treatment room, the three groups of subjects took a comfortable prone position on the massage beds. The massage beds were separated by curtains. The subjects wore loose shorts. The room was quiet and noise-free. The subjects were not allowed to play with mobile phones, watch videos, or do other actions that might affect the test results. The rubbing formula + FIR group used a pre-heated 15-minute Lid brand ordinary far-infrared device to apply hot compresses to the neck and shoulder girdle of the patients. They lay still for 25 minutes according to the test requirements, and then a dedicated person was responsible for data testing and collection.

[0048] Table 1 Treatment effect of patients after 4 weeks of treatment

[0049] Morning stiffness time (minutes) Upper limb raising degree (points) VAS evaluation (points) Massage Group Before treatment 32.41 1.68 5.32 After treatment 21.53 1.05 2.53 Rub-on group Before treatment 31.99 1.72 5.49 After treatment 18.27 0.84 1.73 Turuofang+FIR group Before treatment 31.54 1.71 5.64 After treatment 16.76 0.64 1.36

[0050] According to the data in Table 1 and Figure 1 , 2 As shown in the figure, the Chinese medicine rubbing prescription proposed by the present invention has a good therapeutic effect. The effect is more significant when combined with far-infrared intervention treatment.

[0051] The above contents are merely examples and explanations of the concept of the present invention. The technicians in this technical field may make various modifications or additions to the specific embodiments described or replace them in a similar manner. As long as they do not deviate from the concept of the invention or exceed the scope defined by the claims, they should all fall within the protection scope of the present invention.

Claims

1. A Chinese medicine rubbing prescription for nourishing the liver and kidney as a drug for treating polymyalgia rheumatica, characterized in that: The effective ingredients of the Chinese medicine rubbing prescription for nourishing the liver and kidney are prepared from the following Chinese medicine raw materials by weight:

2. The use according to claim 1, characterized in that The effective ingredients of the liver-nourishing and kidney-nourishing Chinese medicine rubbing prescription are prepared from the following Chinese medicine raw materials by weight:

3. The use according to claim 1 or 2, characterized in that: The preparation method of the Chinese medicine rubbing prescription for nourishing the liver and kidneys has the following steps: (1) First, wash and dry each Chinese herbal medicine component and weigh it according to the amount; (2) Grind the 16 medicinal materials except the far-infrared ceramic powder into powder, add the far-infrared ceramic powder, and stir evenly; (3) adding the above-mentioned finely ground raw materials to lotus paste, with the weight ratio of Chinese medicine powder to lotus paste being 3:1; (4) Place the prepared ointment on paper and spread it flat to prepare A traditional Chinese medicine rubbing prescription for treating polymyalgia rheumatica.

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