Traditional Chinese medicine composition as well as decoction method and application thereof

Abstract

The invention relates to a traditional Chinese medicine composition. Comprising dried ginger, fried semen brassicae, schisandra chinensis, asarum, platycodon grandiflorum, ephedra, ginger processed pinellia, semen armeniacae amarae, rhizoma acori graminei, radix bupleuri, fried radix paeoniae alba, fried fructus aurantii, fried fructus aurantii immaturus, pericarpium citri reticulatae, radix paeoniae rubra seaweed, flos farfarae, pericarpium citri reticulatae viride, blackberry lily, herba epimedii, fried rhizoma atractylodis macrocephalae, fried semen raphani, codonopsis pilosula, trichosanthes kirilowii maxim, honey loquat leaves, honey violet, glossy privet fruit, peach kernels, rhizoma bolbostemmae, radix curcumae, thunberg fritillary bulb, glabrous sarcandra herb, semen cuscutae, radix glehniae, fried endothelium corneum gigeriae galli and The traditional Chinese medicine composition is prepared from poria cocos, gypsum, radix pseudostellariae, salted eucommia ulmoides, amethyst, fried coix seeds, calcined concha arcae, cortex magnoliae officinalis, astragalus membranaceus, adenophora tetraphylla, salvia chinensis, radix actinidiae chinensis, houttuynia cordata, cortex lycii radicis, Chinese waxgourd seeds, oysters and fried cowherb seeds. Compared with the prior art, the traditional Chinese medicine composition disclosed by the invention has obvious differences in component selection, action mechanism, clinical curative effect, safety and indication coverage range, has high innovation value and practical significance, and opens up a new path for treating pulmonary nodules.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicines, and in particular to a traditional Chinese medicine composition and a decocting method and application thereof. Background Art

[0002] As a type of increasingly common lung disease, multiple pulmonary nodules have attracted widespread attention from the medical community due to their increasing incidence rate year by year. Although Western medicine provides certain solutions, it is limited by the limitations of treatment methods and some patients' intolerance to Western medicine. Finding safer and more effective treatment methods has become an urgent need. In this context, traditional Chinese medicine treatment, with its unique concept of syndrome differentiation and treatment and relatively small side effects, has shown its potential in improving patients' clinical symptoms, shrinking or even eliminating lung nodules. Traditional Chinese medicine treatment emphasizes individualization. By comprehensively considering multiple factors such as the patient's constitution, course of disease, and etiology, a personalized treatment plan is formulated to achieve better clinical efficacy.

[0003] Therefore, there is an urgent need for a Chinese medicine composition and a decocting method and application thereof. Summary of the invention

[0004] The purpose of the present invention is to provide a Chinese medicine composition and a decoction method and application thereof in view of the deficiencies in the prior art.

[0005] To achieve the above object, the technical solution adopted by the present invention is:

[0006] The first aspect of the present invention is to provide a traditional Chinese medicine composition, comprising: dried ginger, fried white mustard seeds, schisandra chinensis, asarum, platycodon, ephedra, ginger pinellia, bitter almond, calamus, bupleurum, fried white peony root, fried bitter orange peel, fried bitter orange peel, red peony root seaweed, coltsfoot flower, green peel, iris, epimedium, fried atractylodes, fried radish seeds, codonopsis, trichosanthes, honey loquat leaves, honey purple, Ligustrum lucidum fruit, peach kernel, Fritillaria thunbergii, curcuma, Fritillaria thunbergii, swollen joint wind, dodder seed, northern adenophora, fried chicken gizzard lining, floating sea stone, Poria, gypsum, Pseudostellaria zizi, salt eucommia, purple quartz, fried coix seeds, calcined corrugated iron bark, Magnolia officinalis, Astragalus, Adenophora australis, Lithospermum officinale, root of rattan pear, houttuynia cordata, cortex lycii, wax gourd seeds, oyster, and fried fenugreek.

[0007] Preferably, the ingredients, by weight, include: 1-5 parts of dried ginger, 4-8 parts of stir-fried white mustard seeds, 4-8 parts of schisandra chinensis, 4-8 parts of asarum, 6-10 parts of platycodon grandiflorum, 6-10 parts of ephedra, 7-11 parts of ginger pinellia, 7-11 parts of bitter almonds, 7-11 parts of calamus, 10-14 parts of bupleurum, 10-14 parts of stir-fried white peony root, 10-14 parts of stir-fried fructus aurantii, 10-14 parts of stir-fried immature bitter orange peel, 1 0-14 parts, red peony root 10-14 parts, seaweed 10-14 parts, coltsfoot flower 10-14 parts, green peel 10-14 parts, beam dry 10-14 parts, epimedium 10-14 parts, stir-fried atractylodes 13-17 parts, stir-fried radish seeds 13-17 parts, Codonopsis pilosula 13-17 parts, Trichosanthes kirilowii 13-17 parts, honey loquat leaves 13-17 parts, honey purple 13-17 parts, Ligustrum lucidum 13-17 parts , 13-17 parts of peach kernel, 13-17 parts of Tubei, 13-17 parts of Curcuma, 13-17 parts of Zhejiang Fritillaria, 13-17 parts of Zhongjiefeng, 16-20 parts of Cuscuta, 18-22 parts of Northern Adenophora, 18-22 parts of stir-fried chicken gizzard, 18-22 parts of Fuhai Stone, 18-22 parts of Poria, 18-22 parts of Gypsum, 18-22 parts of Pseudostellariae Radix, 18-22 parts of Salt Eucommia, 18-22 parts of Purple Stone 18-22 parts of Radix Coix, 28-32 parts of stir-fried coix seeds, 28-32 parts of calcined corrugated seeds, 28-32 parts of Magnolia officinalis, 28-32 parts of Astragalus, 28-32 parts of Adenophora australis, 28-32 parts of Lithospermum officinale, 28-32 parts of Rhizoma Cynomorii, 28-32 parts of Houttuynia cordata, 43-47 parts of Cortex Lycii, 43-47 parts of Wax gourd seeds, 43-47 parts of Oyster, and 58-62 parts of stir-fried Vaccaria segetalis.

[0008] Preferably, the ingredients, by weight, include: 3 parts of dried ginger, 6 parts of stir-fried white mustard seeds, 6 parts of schisandra chinensis, 6 parts of asarum, 8 parts of platycodon grandiflorum, 8 parts of ephedra, 9 parts of ginger pinellia, 9 parts of bitter almonds, 9 parts of calamus, 12 parts of bupleurum, 12 parts of stir-fried white peony root, 12 parts of stir-fried fructus aurantii, 12 parts of stir-fried immature aurantium, 12 parts of tangerine peel, 12 parts of red peony root, 12 parts of seaweed, 12 parts of coltsfoot flower, 12 parts of green peel, 12 parts of belamcanda chinensis, 12 parts of epimedium, 15 parts of stir-fried atractylodes macrocephala, 15 parts of stir-fried radish seeds, 15 parts of codonopsis pilosula, 15 parts of trichosanthes, 15 parts of honey loquat leaves, 15 parts of honey purple, and 15 parts of Ligustrum lucidum. , 15 parts of peach kernel, 15 parts of Tubei, 15 parts of Curcuma, 15 parts of Thunbergia, 15 parts of Sarcandra, 18 parts of Cuscuta, 20 parts of Adenophora australis, 20 parts of stir-fried chicken gizzard lining, 20 parts of Fuhai Stone, 20 parts of Poria, 20 parts of Gypsum, 20 parts of Pseudostellaria heterophylla, 20 parts of Salt Eucommia, 20 parts of Amethyst, 30 parts of stir-fried Coix seeds, 30 parts of calcined Corrugated Fructus, 30 parts of Magnolia officinalis, 30 parts of Astragalus, 30 parts of Adenophora australis, 30 parts of Lithospermum officinale, 30 parts of Tengli root, 30 parts of Houttuynia cordata, 45 parts of Lycium bark, 45 parts of Wax gourd seeds, 45 parts of oysters, and 60 parts of stir-fried Vaccaria segetalis.

[0009] The second aspect of the present invention is to provide a method for decocting the Chinese medicine composition as described above, the steps comprising:

[0010] Step 1: Mix gypsum, purple quartz, calcined corrugated stone, and oyster in water, and boil to obtain a first medicinal liquid;

[0011] Step 2: Mix dried ginger, fried white mustard seeds, schisandra, asarum, platycodon, ephedra, ginger pinellia, bitter almond, calamus, bupleurum, fried white peony root, fried bitter orange peel, fried bitter orange peel, tangerine peel, red peony root, seaweed, coltsfoot flower, green peel, iris, epimedium, fried atractylodes, fried radish seeds, codonopsis, trichosanthes, gauze wrapped with honey loquat leaves, honey purple, privet fruit, peach kernel, Fritillaria thunbergii, curcuma, Fritillaria thunbergii, swollen knotweed, dodder seed, northern adenophora, fried chicken gizzard lining, floating sea stone, tuckahoe, pseudostellaria, salt eucommia, fried coix seed, magnolia bark, astragalus, adenophora australis, lithospermum officinale, vine pear root, houttuynia cordata, lycium bark, wax gourd seeds, and fried fenugreek in the first medicinal liquid, and decoct to obtain the second medicinal liquid.

[0012] Preferably, in step one,

[0013] Mix gypsum, purple quartz, calcined corrugated stone, and oyster in 2L of water, and boil over high heat for 30 minutes to obtain the first medicinal solution.

[0014] Preferably, in step 2,

[0015] Dried ginger, fried white mustard seeds, schisandra, asarum, platycodon, ephedra, ginger pinellia, bitter almond, calamus, bupleurum, fried white peony root, fried aurantium, fried aurantium immaturum, tangerine peel, red peony root, seaweed, coltsfoot flower, green peel, iris, epimedium, fried atractylodes, fried radish seeds, codonopsis, trichosanthes, gauze wrapped with honey loquat leaves, honey purple, privet fruit, peach kernel, Fritillaria thunbergii, curcuma, Fritillaria thunbergii, swollen knotweed , Cuscuta australis, Adenophora dahurica, stir-fried chicken gizzard lining, Fuhai stone, Poria, Pseudostellaria heterophylla, Eucommia ulmoides, stir-fried Coix seeds, Magnolia officinalis, Astragalus, Adenophora australis, Lithospermum officinale, Pyrus trichosanthis, Houttuynia cordata, Lycium bark, Wax gourd seeds, and stir-fried Vaccaria segetalis are mixed in the first medicinal liquid, simmered until the volume of the medicinal liquid is 400 mL, and then simmered for 10 min-20 min to obtain the second medicinal liquid.

[0016] The third aspect of the present invention is to provide a Chinese medicine composition as described above, or the use of the medicinal liquid prepared by the decoction method as described above in the preparation of a medicine for treating multiple pulmonary nodules.

[0017] The present invention adopts the above technical solution, and has the following technical effects compared with the prior art:

[0018] The Chinese medicine composition of the present invention and its decoction method and application are significantly different from the prior art in terms of ingredient selection, mechanism of action, clinical efficacy, safety and scope of indications, and have high innovative value and practical significance, opening up a new path for the treatment of pulmonary nodules. Specifically:

[0019] The Chinese medicine composition of the present invention, through the scientific compatibility of medicinal materials, follows the theories of traditional Chinese medicine such as strengthening the body and eliminating evil, promoting lung function and resolving phlegm, strengthening the spleen and soothing the liver, regulating qi and softening and dispersing nodules, regulating qi and blood, clearing away heat and detoxifying, and nourishing yin and moistening the lungs, and constructs a complex system that comprehensively covers the treatment needs of lung nodules, especially in the treatment of lung nodules of phlegm, turbidity and blood stasis and qi stagnation type, and shows excellent clinical effects;

[0020] Different from the single action mode of traditional therapies, the Chinese medicine composition of the present invention achieves the goal of strengthening the body and dispelling evil, harmonizing qi and blood through the synergistic effect of multiple ingredients, and intervenes at multiple levels such as soothing the liver and regulating qi, resolving phlegm and removing blood stasis, clearing away heat and detoxifying, softening and dispersing nodules, etc., targeting the pathogenesis of lung nodules, fundamentally improving the lesion environment, promoting lesion absorption, and achieving comprehensive conditioning and treatment;

[0021] The Chinese medicine composition of the present invention has shown remarkable results in the treatment of pulmonary nodules, and can significantly reduce the size of the lesions in a short period of time, or even completely absorb them. Compared with the treatment methods in the prior art, the present invention has achieved a significant breakthrough in cure rate and efficacy.

[0022] The medicinal materials selected for the Chinese medicine composition of the present invention are relatively mild, and the side effects on the liver, kidneys and other organs of the human body after long-term use are extremely low. At the same time, Chinese medicine treatment focuses on overall conditioning, which helps to restore the body's self-healing ability, reduce the adverse reactions that may be caused by Western medicine treatment, and ensure the safety and comfort of patients during the treatment process;

[0023] The Chinese medicine composition of the present invention shows good adaptability to different pathological types of lung nodules, such as phlegm-dampness blocking the lungs, qi stagnation and blood stasis, yin deficiency and hyperactivity of fire, and lung and spleen qi deficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 This is a comparison of nodule diameters before and after treatment in each group;

[0025] Figure 2 This is a cross-comparison chart of the treatment efficacy of each group. DETAILED DESCRIPTION

[0026] The specific embodiments of the present invention will be described in detail below.

[0027] Unless otherwise defined, technical or scientific terms used in the claims and the specification shall have the common meanings understood by persons having ordinary skills in the technical field to which the present invention belongs.

[0028] The words "include" or similar words used in the patent application specification and claims of the present invention mean that the items appearing before "include" include the items listed after "include" or their equivalents, and do not exclude other items.

[0029] The numerical values ​​mentioned in the present invention include all numerical values ​​that increase from low to high by one unit, assuming that there are at least two units between any lower value and the higher value. For example, if a component or a physical quantity is said to be from 1 to 100, 10 to 90 is more preferred, and 20 to 80 is the most preferred, it is intended to express that values ​​such as 5 to 95, 14 to 76, 23 to 67, 32 to 58, 41 to 49 are clearly listed in this specification; for values ​​less than 1, 0.0001, 0.001, 0.01 or 0.1 are considered to be more suitable as a unit. The above examples are for illustrative purposes only. In fact, all numerical combinations between the lowest value and the highest value listed are deemed to be clearly listed in this specification in a similar manner.

[0030] Example 1

[0031] The present embodiment provides a traditional Chinese medicine composition, which comprises, by weight: 3g of dried ginger, 6g of stir-fried white mustard seeds, 6g of schisandra chinensis, 6g of asarum, 8g of platycodon grandiflorum, 8g of ephedra, 9g of ginger pinellia, 9g of bitter almond, 9g of calamus, 12g of bupleurum, 12g of stir-fried white peony root, 12g of stir-fried fructus aurantii, 12g of stir-fried immature bitter orange peel, 12g of red peony root, 12g of seaweed, 12g of coltsfoot flower, 12g of green peel, 12g of belamcanda chinensis, 12g of epimedium, 15g of stir-fried atractylodes, 15g of stir-fried radish seeds, 15g of codonopsis pilosula, 15g of trichosanthes, 15g of honey loquat leaves, 15g of honey purple, 15g of female 15g of Zhenzi, 15g of peach kernel, 15g of Tubeimu, 15g of Curcuma, 15g of Zhejiang Fritillary, 15g of Sarcandra, 18g of Cuscuta, 20g of Northern Adenophora, 20g of stir-fried chicken gizzard lining, 20g of Fuhai Stone, 20g of Poria, 20g of Gypsum, 20g of Pseudostellaria, 20g of Salt Eucommia, 20g of Purple Quartz, 30g of stir-fried Coix seeds, 30g of calcined Corrugated Iron Fern, 30g of Magnolia officinalis, 30g of Astragalus, 30g of Southern Adenophora, 30g of Lithospermum officinale, 30g of Tengli root, 30g of Houttuynia cordata, 45g of Rehmannia root bark, 45g of Wax Melon Seed, 45g of Oyster, and 60g of stir-fried Vaccaria.

[0032] Example 2

[0033] This embodiment provides a method for decocting the Chinese medicine composition as described in Embodiment 1, the steps comprising:

[0034] Step 1: Mix gypsum, purple quartz, calcined corrugated paper, and oyster in 2L of water, and boil over high heat for 30 minutes to obtain the first medicinal solution;

[0035] Step 2: Add dried ginger, fried white mustard seeds, schisandra, asarum, platycodon, ephedra, ginger pinellia, bitter almond, calamus, bupleurum, fried white peony root, fried aurantium, fried aurantium, tangerine peel, red peony root, seaweed, coltsfoot flower, green peel, iris, epimedium, fried atractylodes, fried radish seeds, codonopsis, trichosanthes, gauze wrapped with honey loquat leaves, honey purple, privet fruit, peach kernel, Fritillaria thunbergii, turmeric, Fritillaria thunbergii, swelling The first medicinal liquid is mixed with Radix et Rhizoma Jiefeng, Semen Cuscutae, Radix Adenophorae, stir-fried Gallus gallus domesticus, Fuhai Stone, Poria, Radix Pseudostellariae, Eucommia bark, stir-fried Semen Coicis, Magnolia officinalis, Radix Astragali, Radix Adenophorae, Radix Lithospermi, Root of Pyrus truncatula, Houttuynia cordata, Cortex Lycii, Seed of Wax Melon, and stir-fried Vaccaria segetalis, and the mixture is decocted over low heat until the volume of the medicinal liquid is 400 mL, and then decocted over low heat for 10 min-20 min to obtain the second medicinal liquid.

[0036] Example 3

[0037] This embodiment provides a use of the Chinese medicine composition as described in Example 1, or the medicinal liquid prepared by the decoction method as described in Example 2 in the preparation of a medicine for treating multiple pulmonary nodules.

[0038] The cases were selected from patients who visited the fever clinic, emergency internal medicine department, and traditional Chinese medicine department of Jinshan Hospital Affiliated to Fudan University from October 2018 to March 2024. They were randomly divided into a Chinese medicine compound treatment group, an antibiotic treatment group, and an untreated group according to the random number table method. The information is shown in the following table:

[0039] Chinese medicine compound treatment group Antibiotic treatment group Untreated group <![CDATA[F / χ 2 ]]> P age 46.400±13.820 52.250±19.695 49.650±16.044 0.616 0.543 gender 0.533 0.766 female 14(70.000) 16(80.000) 15(75.000) male 6(30.000) 4(20.000) 5(25.000)

[0040] There was no significant difference in the baseline information of the three groups of patients (P>0.05), and they were comparable.

[0041] Western medicine diagnostic standards: Refer to the diagnostic standards for lung nodules in the "Chinese Expert Consensus on the Diagnosis and Treatment of Pulmonary Nodules" (2018 edition). The imaging manifestations are focal, round, increased density, solid or subsolid lung shadows with a diameter of ≤3 cm, which may be isolated or multiple, without atelectasis, bronchohilar lymphadenopathy and pleural effusion.

[0042] TCM diagnostic criteria: There is no clear unified TCM diagnostic criteria for lung nodules, but it can be analyzed based on clinical manifestations, imaging examination results, and TCM syndrome differentiation and treatment principles. The following are some key points that can be used as a reference for TCM diagnosis of lung nodules:

[0043] 1. Clinical manifestations: Patients with lung nodules may experience symptoms such as cough, sputum, shortness of breath, chest pain, and fever. The severity and characteristics of the symptoms can be used to identify the cold, heat, deficiency, and excess of the disease.

[0044] 2. Imaging examination: Through chest CT, X-ray and other examinations, the size, shape, density and other characteristics of lung nodules are observed, and analyzed in combination with traditional Chinese medicine theory; if the nodule has a smooth shape and clear edges, it may be a benign lesion; if the nodule has an irregular shape and blurred edges, it may be a malignant lesion.

[0045] 3. TCM syndrome differentiation and treatment: According to the patient's constitution, medical history, symptoms and imaging examination results, the principles of TCM syndrome differentiation and treatment are applied to determine the TCM syndrome of lung nodules; common TCM syndromes include phlegm and dampness blocking the lungs, qi stagnation and blood stasis, yin deficiency and hyperactivity of fire, and lung and spleen qi deficiency.

[0046] 4. Disease staging: The lung nodules are staged based on the results of imaging examinations and TCM symptoms. For example, in the early stage of lung nodules, the pathogenic factors are relatively shallow and the vital energy is still sufficient. In the middle stage of lung nodules, the pathogenic factors gradually become deeper and the vital energy is damaged. In the late stage of lung nodules, the disease worsens and pulmonary insufficiency or lung cancer may occur.

[0047] Inclusion criteria: ① those who meet the diagnostic criteria for multiple pulmonary nodules; ② those who agree to be conservative users; ③ those aged 18-90 years old, regardless of gender; ④ those with a history of other tumors except lung cancer, and the possibility of tumor recurrence or lung metastasis has been ruled out.

[0048] Exclusion criteria: ① patients with obvious surgical indications and no obvious effect of conservative treatment; ② imaging characteristics include spicule sign, lobulation sign, cavitation sign, pleural traction sign, cavity sign, etc.; ③ patients with severe visceral diseases, functional insufficiency or multiple systemic tumors or severe mental illness; ④ pregnant and lactating women; ⑤ patients who take hormones for a long time or have severe mental illness and are unable to cooperate with the investigation.

[0049] Chinese medicine compound treatment group: use the Chinese medicine composition as described in Example 1, or the liquid medicine prepared by the decoction method as described in Example 2, twice a day, for 4 consecutive months. During use, patients with pneumonia, local skin infection, systolic blood pressure of more than 180 mmHg, severe acute bleeding, and severe heart disease are strictly prohibited from using.

[0050] Antibiotic treatment group: Western medicine anti-inflammatory and anti-infection treatment, oral cefixime 0.1g, combined with levofloxacin hydrochloride capsule 0.2g, twice a day, a course of 14 days, followed by observation for 3.5 months.

[0051] Untreated group: Observe the changes of lung nodules for 4 months without treatment.

[0052] The results are shown in the following table: Figure 1 As shown,

[0053] Chinese medicine compound treatment group Antibiotic treatment group Untreated group <![CDATA[F / χ 2 ]]> P Nodule diameter before treatment 8.503±1.798 8.357±2.267 7.809±3.068 0.451 0.639 Nodule diameter after treatment <![CDATA[4.533±1.465 ab ]]> <![CDATA[6.743±1.698 a ]]> 7.685±1.622 20.517 0.000** t 8.179 2.772 0.178 p 0.000** 0.012* 0.861

[0054] Note: *P<0.05, **P<0.01, a means P<0.05 compared with the untreated group, b means P<0.05 compared with the antibiotic treatment group

[0055] The treatment method showed a significant effect on the nodule diameter after treatment at the 0.01 level (F=20.517, P=0.000), and the specific comparison differences showed that there were obvious differences between the Chinese medicine compound treatment group, the antibiotic treatment group, and the untreated group.

[0056] The difference between the nodule diameter before and after treatment in the antibiotic treatment group showed a significance level of 0.05 (t=2.772, p=0.012), and the specific comparison difference showed that the average nodule diameter before treatment (8.36) was significantly higher than the average nodule diameter after treatment (6.74).

[0057] The difference between the nodule diameter before treatment and the nodule diameter after treatment in the Chinese medicine compound treatment group showed a significance level of 0.05 (t=2.772, p=0.012), and the specific comparison difference showed that the average nodule diameter before treatment (8.36) was significantly higher than the average diameter after treatment (6.74).

[0058] Group Number of cases Obvious absorption absorb Unabsorbed deterioration Total efficiency Chinese medicine compound treatment group 20 15(75.000) 2(10.000) 2(10.000) 1(5.000) <![CDATA[95.00% #▲ ]]> Antibiotic treatment group 20 2(10.000) 5(25.000) 8(40.000) 5(25.000) <![CDATA[75.00% # ]]> Untreated group 20 0(0.000) 0(0.000) 13(65.000) 7(35.000) 65.00％

[0059] Note: # Compared with the untreated group, P < 0.05. ▲ Compared with the antibiotic treatment group, P < 0.05

[0060] In summary, the Chinese medicine composition of the present invention, its decoction method and application, all show significant differences from the prior art in terms of ingredient selection, mechanism of action, clinical efficacy, safety and scope of indications, have high innovative value and practical significance, and have opened up a new path for the treatment of pulmonary nodules.

[0061] The above description is only a preferred embodiment of the present invention, and does not limit the implementation mode and protection scope of the present invention. For those skilled in the art, it should be aware that all solutions obtained by equivalent substitutions and obvious changes made using the description and illustrations of the present invention should be included in the protection scope of the present invention.

Claims

1. A Chinese medicine composition, characterized in that: include: Dried ginger, fried white mustard seeds, schisandra, asarum, platycodon, ephedra, ginger pinellia, bitter almond, calamus, bupleurum, fried white peony root, fried bitter orange peel, fried bitter orange peel, tangerine peel, red peony root, seaweed, coltsfoot, green peel, iris, epimedium, fried atractylodes, fried radish seeds, codonopsis, trichosanthes, honey loquat leaves, honey purple, Ligustrum lucidum, peach kernel, Fritillaria thunbergii, curcuma, Fritillaria thunbergii, swollen knotweed, dodder seed, northern adenophora, fried chicken gizzard lining, floating sea stone, Poria, gypsum, pseudostellaria, salt eucommia, purple quartz, fried coix seed, calcined corrugated iron bark, Magnolia officinalis, Astragalus, Adenophora australis, Lithospermum officinale, Pyrus nobilis, Houttuynia cordata, Lycium bark, wax gourd seeds, oyster, and fried fenugreek.

2. The Chinese medicine composition according to claim 1, characterized in that: The ingredients include, by weight: 1-5 parts of dried ginger, 4-8 parts of stir-fried white mustard seeds, 4-8 parts of schisandra chinensis, 4-8 parts of asarum, 6-10 parts of platycodon grandiflorum, 6-10 parts of ephedra, 7-11 parts of ginger pinellia, 7-11 parts of bitter almonds, 7-11 parts of calamus, 10-14 parts of bupleurum, 10-14 parts of stir-fried white peony root, 10-14 parts of stir-fried fructus aurantii, 10-14 parts of stir-fried immature bitter orange peel, 10-1 4 parts, 10-14 parts of red peony root, 10-14 parts of seaweed, 10-14 parts of coltsfoot flower, 10-14 parts of green peel, 10-14 parts of beam stem, 10-14 parts of epimedium, 13-17 parts of stir-fried atractylodes, 13-17 parts of stir-fried radish seeds, 13-17 parts of codonopsis, 13-17 parts of trichosanthes, 13-17 parts of honey loquat leaves, 13-17 parts of honey purple, 13-17 parts of Ligustrum lucidum, peach 13-17 parts of kernel, 13-17 parts of Fritillaria thunbergii, 13-17 parts of Curcuma aromatica, 13-17 parts of Fritillaria thunbergii, 13-17 parts of Sarcandra scutellariae, 16-20 parts of Cuscuta australis, 18-22 parts of Adenophora scutellariae, 18-22 parts of stir-fried chicken gizzard lining, 18-22 parts of Fuhai stone, 18-22 parts of Poria cocos, 18-22 parts of Gypsum, 18-22 parts of Pseudostellaria heterophylla, 18-22 parts of Eucommia ulmoides, 18-22 parts of Amethyst 18-22 parts, stir-fried coix seeds 28-32 parts, calcined corrugated seeds 28-32 parts, Magnolia officinalis 28-32 parts, Astragalus 28-32 parts, Adenophora australis 28-32 parts, Lithospermum officinale 28-32 parts, Pyrus trichosanthis root 28-32 parts, Houttuynia cordata 28-32 parts, Cortex Lycii 43-47 parts, Wax gourd seeds 43-47 parts, Oyster 43-47 parts, and stir-fried Vaccaria segetalis 58-62 parts.

3. The Chinese medicine composition according to claim 1 or 2, characterized in that: The ingredients are calculated by weight: 3 parts of dried ginger, 6 parts of stir-fried white mustard seeds, 6 parts of schisandra chinensis, 6 parts of asarum, 8 parts of platycodon grandiflorum, 8 parts of ephedra, 9 parts of ginger pinellia, 9 parts of bitter almonds, 9 parts of calamus, 12 parts of bupleurum, 12 parts of stir-fried white peony root, 12 parts of stir-fried fructus aurantii, 12 parts of stir-fried immature bitter orange peel, 12 parts of red peony root, 12 parts of seaweed, 12 parts of coltsfoot flower, 12 parts of green peel, 12 parts of belamcanda chinensis, 12 parts of epimedium, 15 parts of stir-fried atractylodes, 15 parts of stir-fried radish seeds, 15 parts of codonopsis pilosula, 15 parts of trichosanthes, 15 parts of honey loquat leaves, 15 parts of honey purple, 15 parts of glossy privet fruit, 12 parts of peach 15 parts of Radix Codonopsis pilosulae, 15 parts of Radix Fritillariae Tuberosum, 15 parts of Radix Curcumae, 15 parts of Fritillariae Thunbergii, 15 parts of Radix Sarcosomae Sarcosae, 18 parts of Semen Cuscutae, 20 parts of Radix Adenophorae Northernis, 20 parts of stir-fried Gallus gallus tuber, 20 parts of Puhai Stone, 20 parts of Poria, 20 parts of Gypsum, 20 parts of Radix Pseudostellariae Pseudostellariae, 20 parts of Salt Eucommia Bark, 20 parts of Amethyst, 30 parts of stir-fried Semen Coicis, 30 parts of calcined Fructus Corrugae, 30 parts of Magnolia Bark, 30 parts of Radix Astragali, 30 parts of Radix Adenophorae Southernis, 30 parts of Lithospermum Officinale, 30 parts of Radix Pyriferae, 30 parts of Houttuynia Cortex, 45 parts of Cortex Lycii, 45 parts of Seeds of Wax Gourd, 45 parts of Oyster, and 60 parts of stir-fried Vaccariae Semen.

4. A method for decocting the Chinese medicine composition according to any one of claims 1 to 3, characterized in that the steps include: Step 1: Mix gypsum, purple quartz, calcined corrugated stone, and oyster in water, and boil to obtain a first medicinal liquid; Step 2: Mix dried ginger, fried white mustard seeds, schisandra, asarum, platycodon, ephedra, ginger pinellia, bitter almond, calamus, bupleurum, fried white peony root, fried bitter orange peel, fried bitter orange peel, tangerine peel, red peony root, seaweed, coltsfoot flower, green peel, iris, epimedium, fried atractylodes, fried radish seeds, codonopsis, trichosanthes, gauze wrapped with honey loquat leaves, honey purple, privet fruit, peach kernel, Fritillaria thunbergii, curcuma, Fritillaria thunbergii, swollen knotweed, dodder seed, northern adenophora, fried chicken gizzard lining, floating sea stone, tuckahoe, pseudostellaria, salt eucommia, fried coix seed, magnolia bark, astragalus, adenophora australis, lithospermum officinale, vine pear root, houttuynia cordata, lycium bark, wax gourd seeds, and fried fenugreek in the first medicinal liquid, and decoct to obtain the second medicinal liquid.

5. The decoction method according to claim 4, characterized in that: In step one, Mix gypsum, purple quartz, calcined corrugated stone, and oyster in 2L of water, and boil over high heat for 30 minutes to obtain the first medicinal solution.

6. The decoction method according to claim 4, characterized in that: In step 2, Dried ginger, fried white mustard seeds, schisandra, asarum, platycodon, ephedra, ginger pinellia, bitter almond, calamus, bupleurum, fried white peony root, fried aurantium, fried aurantium immaturum, tangerine peel, red peony root, seaweed, coltsfoot flower, green peel, iris, epimedium, fried atractylodes, fried radish seeds, codonopsis, trichosanthes, gauze wrapped with honey loquat leaves, honey purple, privet fruit, peach kernel, Fritillaria thunbergii, curcuma, Fritillaria thunbergii, swollen knotweed , Cuscuta australis, Adenophora dahurica, stir-fried chicken gizzard lining, Fuhai stone, Poria, Pseudostellaria heterophylla, Eucommia ulmoides, stir-fried Coix seeds, Magnolia officinalis, Astragalus, Adenophora australis, Lithospermum officinale, Pyrus trichosanthis, Houttuynia cordata, Lycium bark, Wax gourd seeds, and stir-fried Vaccaria segetalis are mixed in the first medicinal liquid, simmered until the volume of the medicinal liquid is 400 mL, and then simmered for 10 min-20 min to obtain the second medicinal liquid.

7. Use of the Chinese medicine composition as claimed in any one of claims 1 to 3, or the medicinal liquid prepared by the decocting method as claimed in any one of claims 4 to 6, in the preparation of a medicine for treating multiple pulmonary nodules.

Images