Biological sample low-temperature storage refrigerator

Through the design of the lifting shovel mechanism and Stirling refrigeration mechanism in the low temperature storage refrigerator of biological samples, the problems such as mechanical damage and large liquid consumption during the sample storage and use are solved, and efficient and safe sample management and safe sample management and safe samples Low -cost liquid nitrogen.

CN119334033APending Publication Date: 2025-01-21SHANGHAI ORIGINCELL BIOLOGICAL CRYO EQUIP CO LTD
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Patent Information

Application Number
CN202411020018.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-07-29
Publication Date
2025-01-21

AI Technical Summary

Technical Problem

Existing biological sample low-temperature storage equipment can easily cause damage in the long-term operation of the robotic arm in ultra-low temperature environment, affecting the accuracy of sample storage and use. At the same time, liquid nitrogen consumption is high, and the cost is high, and the safety of the shovel mechanism is low, which can easily cause the sample box to fall off. .

Method used

Design a biological sample low temperature storage refrigerator, and use the lifting shovel mechanism to use the sample box in the sample storage tank to remove and transfer, and to adjust the components and grab components to achieve the clamping and safe transfer of the sample box through the angle. At the same time, the Sterling refrigeration mechanism is used to circulate and vaporize and liquefaction of liquid nitrogen, saving the amount of liquid nitrogen, reducing costs, and realizing automatic temperature adjustment.

Benefits of technology

It improves the efficiency and safety of the shovel and transport of the sample box, reduce the amount and cost of liquid nitrogen, and ensure the safety and stability of the sample during the storage and use.

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Abstract

The invention discloses a biological sample low-temperature storage refrigerator which comprises a sample storage cabin, an operation area and a refrigeration mechanism. An operation area is arranged on the side edge of the sample storage cabin, a refrigeration mechanism is arranged on the sample storage cabin, and the refrigeration mechanism can refrigerate the interior of the sample storage cabin; the operation area can be used for storing and taking samples in the sample storage cabin, transferring and picking the samples, and the sample storage cabin can be used for storing the samples in the basket; a lifting shovel plate mechanism is arranged in the operation area and can grab and transfer sample boxes. The device has the beneficial effects that the lifting shovel plate mechanism penetrates through the revolving door assembly to shovel and transfer the sample box in the sample storage cabin, the lifting shovel plate mechanism can shovel samples and clamp the samples, it can be guaranteed that the sample box cannot fall off, Stirling refrigeration is adopted by the refrigeration mechanism, the usage amount of liquid nitrogen can be reduced, and the sample box can be conveniently stored. The cost of using liquid nitrogen for a long time is reduced, the liquid nitrogen can be used for a long time after being supplemented once, and automatic temperature adjustment can be achieved.
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Description

Technical Field

[0001] The invention relates to the technical field of sample storage, in particular to a biological sample low-temperature storage refrigerator. Background Art

[0002] In the field of biological sample storage, cryogenic storage and retrieval equipment is used to store biological samples such as blood samples, vaccines, bacteria and virus strains at low temperatures, so that the samples are kept in a low temperature state and preserved active.

[0003] The publication number is CN116409573A, and the application date is 2023.02.27. A fully automatic sample low-temperature storage and retrieval system is disclosed, in which two sets of rotating drums for storing plate racks are arranged in its shell, thereby improving its storage capacity. At the same time, the rotating drum is a single-layer rotating drum, which greatly simplifies the complexity of the lifting and shoveling mechanism for storing and retrieving plate racks; however, the two storage devices arranged in the sample storage shell are both in an ultra-low temperature environment, and the mechanical arm arranged in the middle is easily damaged by long-term work, which affects the accuracy of its precise picking of plate racks, thereby causing extremely serious impact on sample safety; and the currently used liquid nitrogen consumes too much and the cost of liquid nitrogen is relatively high; and the currently used shoveling mechanism has low safety, and there is a risk of falling off during the shoveling and transportation of the sample box. For this reason, the inventor has designed a biological sample low-temperature storage refrigerator with large storage capacity and safe shoveling process. Summary of the invention

[0004] The purpose of this section is to summarize some aspects of embodiments of the present invention and briefly introduce some preferred embodiments. Some simplifications or omissions may be made in this section and the specification abstract and the invention title of this application to avoid blurring the purpose of this section, the specification abstract and the invention title, and such simplifications or omissions cannot be used to limit the scope of the present invention.

[0005] In view of the above problems or problems existing in the prior art, the present invention is proposed.

[0006] Therefore, the purpose of the present invention is to provide a biological sample low-temperature storage refrigerator, which can scoop samples from the sample storage compartment through a shoveling mechanism, and can ensure the clamping operation of the sample box during the scooping process and transportation. After scooping to a specific position, the sample box can be stored, which improves the scooping efficiency and safety, and reduces the risk of the sample box falling during the scooping process. Refrigeration can be carried out by compressor refrigeration or Stirling refrigeration. By using Stirling refrigeration, liquid nitrogen can be circulated, vaporized and liquefied, thereby saving liquid nitrogen, greatly reducing the cost of liquid nitrogen, and realizing the automatic temperature adjustment function.

[0007] In order to solve the above technical problems, the present invention provides the following technical solutions: a biological sample low-temperature storage refrigerator, which includes a sample storage cabin, an operation area, and a refrigeration mechanism; the operation area is arranged on the side of the sample storage cabin, and the refrigeration mechanism is arranged on the sample storage cabin, and the refrigeration mechanism can cool the sample storage cabin; the operation area can store and retrieve samples in the sample storage cabin, and the sample storage cabin can store basket samples; a lifting shovel mechanism is arranged in the operation area, and the lifting shovel mechanism can grab and transport sample boxes.

[0008] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, the lifting shovel plate mechanism includes an angle adjustment component and a grabbing component; the angle adjustment component can perform at least one level of rotation, and a grabbing component is arranged on the angle adjustment component, the angle adjustment component can drive the grabbing component to turn, and the grabbing component can scoop and store the sample box inside the sample storage compartment.

[0009] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, the grabbing assembly includes a supporting telescopic member and a grabbing member; the supporting telescopic member can drive the grabbing member to move horizontally, and the sample box can be scooped by the grabbing member.

[0010] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, the grabbing component also includes a guide limit frame, which is connected to the supporting telescopic member, and the guide limit frame can clamp the grabbing member.

[0011] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, wherein: the supporting telescopic member includes a supporting plate, a first driving member, and a first follower; one end of the supporting plate is connected to the angle adjustment component, the first driving member is arranged on the supporting plate, the first follower is arranged on the side of the first driving member, the front end of the first follower is connected to the grabbing member, the first driving member can drive the first follower to move horizontally along the supporting plate, and the first follower can drive the grabbing member to move horizontally.

[0012] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, the grabbing member includes a supporting claw, an elastic telescopic member, and a guide end; the elastic telescopic members are respectively arranged on both sides of the front end of the first follower, the side of the elastic telescopic member is arranged with a supporting claw, and the outer side of the supporting claw is arranged with a guide end, and the guide end can guide the supporting claw to enter the guide limit frame.

[0013] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, the two groups of supporting jaws can move away from or towards each other, and the supporting jaws can clamp or loosen the plate rack.

[0014] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, the first follower can pass through the guide limit frame to be connected with the grabbing member.

[0015] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, wherein: the angle adjustment component includes a primary rotating part, a secondary rotating part, and a tertiary rotating part; the two sides of the secondary rotating part are respectively connected to the primary rotating part and the tertiary rotating part, one end of the tertiary rotating part is connected to the grasping component, and the primary rotating part, the secondary rotating part, and the tertiary rotating part can all rotate at different angles.

[0016] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, it also includes a vertical driving mechanism, on which an angle adjustment component is provided, and the vertical driving mechanism can drive the angle adjustment component and the grabbing component to move up and down.

[0017] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, the refrigeration mechanism is a compressor refrigeration mechanism or a Stirling refrigeration mechanism, the Stirling refrigeration mechanism is arranged at the upper end of the sample storage compartment, and the compressor refrigeration mechanism is arranged at the side end of the sample storage compartment.

[0018] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, a ventilation mechanism is arranged in the compressor refrigeration mechanism, and the ventilation mechanism can ventilate the compressor refrigeration mechanism. A maintenance port is also arranged on the compressor refrigeration mechanism, and the compressor refrigeration mechanism can be repaired through the maintenance port.

[0019] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, the ventilation mechanism includes an exhaust member and a pipe; the exhaust member is arranged in the pipe, one end of the pipe is connected to the compressor refrigeration mechanism, and the other end passes through the operating area and leads to the outside of the operating area.

[0020] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, wherein: the Stirling refrigeration mechanism includes a Stirling refrigeration module, a cold head, and a storage cavity; the lower end of the Stirling refrigeration module is connected to the cold head, the storage cavity and the Stirling refrigeration module are detachably connected, and the cold head is arranged inside the storage cavity, liquid nitrogen can be stored in the storage cavity, and the cold head can liquefy the vaporized nitrogen.

[0021] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, a revolving door assembly is also provided on the sample storage compartment, and the revolving door assembly is arranged inside the operating area, and the revolving door assembly can open and close the scooping channel.

[0022] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, the revolving door assembly includes a revolving door driver and a revolving door; the lower end of the revolving door driver is connected to the revolving door, and the revolving door driver can drive the revolving door to open and close the scooping channel.

[0023] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, a rotatable storage rack assembly is provided in the sample storage compartment, and the rotatable storage rack assembly can store and retrieve sample boxes.

[0024] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, a transfer port is arranged on the side of the operation area, a transfer door is arranged in the transfer port, and the transfer door can be opened and closed by the transfer port.

[0025] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, a code scanning mechanism is provided on the side of the transfer door, and the code scanning mechanism can scan the sample box.

[0026] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, a storage compartment inspection port is opened on the sample storage compartment, and an inspection door is arranged inside the storage compartment inspection port. The inspection door can open and close the storage compartment inspection port, and the interior of the sample storage compartment can be inspected when the inspection door is opened.

[0027] As a preferred solution of the biological sample low-temperature storage refrigerator of the present invention, a display control device is also provided on the sample storage compartment, and the display control device can display the internal parameters of the sample storage compartment and adjust the control work.

[0028] Beneficial effects of the present invention: the present invention can scoop and transport the sample boxes in the sample storage cabin through the revolving door assembly through the lifting shovel plate mechanism, which can improve the efficiency of scooping the sample boxes. The lifting shovel plate mechanism can scoop and clamp the samples to ensure that the sample boxes will not fall off during the transportation process. The refrigeration mechanism can adopt Stirling refrigeration to reduce the use of liquid nitrogen and the cost of long-term use of liquid nitrogen. Liquid nitrogen can be used for a long time after being replenished once, and automatic temperature adjustment can be achieved. It is not only energy-saving and environmentally friendly, but also easy to disassemble and replace, and easy to clean. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative labor. Among them:

[0030] Figure 1 This is an overall schematic diagram of Example 1 of a biological sample low-temperature storage refrigerator.

[0031] Figure 2 This is a schematic diagram of another perspective of Example 1 of the biological sample low-temperature storage refrigerator.

[0032] Figure 3The compressor refrigeration mechanism in Example 1 of the biological sample low-temperature storage refrigerator.

[0033] Figure 4 This is a schematic diagram of the interior of a biological sample low-temperature storage refrigerator in Example 1.

[0034] Figure 5 This is a three-dimensional schematic diagram of the lifting shovel mechanism of the biological sample low-temperature storage refrigerator.

[0035] Figure 6 Schematic diagram of a rotating storage rack assembly of a biological sample low-temperature storage refrigerator.

[0036] Figure 7 This is an enlarged schematic diagram of the lifting and shoveling mechanism of the biological sample low-temperature storage refrigerator.

[0037] Figure 8 This is a schematic diagram of the lifting and shoveling mechanism of the biological sample low-temperature storage refrigerator.

[0038] Fig. 9 Schematic diagram of the revolving door assembly of a biological sample low-temperature storage refrigerator.

[0039] Fig.10 This is an overall schematic diagram of Example 2 of a biological sample low-temperature storage refrigerator.

[0040] Fig.11 This is a schematic diagram of the operating area of ​​Example 2 of a biological sample low-temperature storage refrigerator.

[0041] Fig.12 This is a schematic diagram of another perspective of Example 2 of the biological sample low-temperature storage refrigerator.

[0042] Fig.13 This is a schematic diagram of the interior of a biological sample low-temperature storage refrigerator in Example 2.

[0043] Fig.14 This is a cross-sectional view of the sample storage compartment in Example 2 of the biological sample low-temperature storage refrigerator.

[0044] Figure numerals: sample storage cabin, 1; operation area, 2; refrigeration mechanism, 3; lifting shovel mechanism, 21; supporting telescopic member, 2121; grabbing member, 2122; guiding limit frame member, 2123; supporting plate, 21211; first driving member, 21212; first driven member, 21213; supporting clamp, 21221; elastic telescopic member, 21222; guide end, 21223; vertical driving mechanism, 213; compressor refrigeration mechanism, 31; Stirling refrigeration mechanism, 32; ventilation mechanism, 33; exhaust member, 331; pipeline, 332; Stirling refrigeration module, 321; cold head, 322; storage chamber, 323; revolving door assembly, 4; revolving door driving member, 41; revolving door, 42; rotating storage rack assembly, 11; transfer door, 29; code scanning mechanism, 5; inspection door, 7; display control device, 8; DETAILED DESCRIPTION

[0045] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are described in detail below in conjunction with the accompanying drawings.

[0046] In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein, and those skilled in the art may make similar generalizations without violating the connotation of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0047] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The term "in one embodiment" that appears in different places in this specification does not necessarily refer to the same embodiment, nor does it refer to a separate or selective embodiment that is mutually exclusive with other embodiments.

[0048] Example 1

[0049] Reference Figures 1 to 9 , which is the first embodiment of the present invention, provides a biological sample low-temperature storage refrigerator, which includes a sample storage cabin 1, an operation area 2, and a refrigeration mechanism 3; the sample storage cabin 1 is provided with a refrigeration mechanism 3, and the sample in the sample storage cabin 1 can be low-temperature frozen by the refrigeration mechanism 3, and the side of the sample storage cabin 1 is provided with an operation area 2, and the sample box in the sample storage cabin 1 can be scooped, transported and picked up by the operation area 2.

[0050] Specifically, the sample storage cabin 1, the operation area 2, and the refrigeration mechanism 3; the side of the sample storage cabin 1 is provided with the operation area 2, and the sample storage cabin 1 is provided with the refrigeration mechanism 3, and the refrigeration mechanism 3 can refrigerate the sample storage cabin 1; the operation area 2 can store and retrieve the samples in the sample storage cabin 1, and the sample storage cabin 1 can store the basket samples;

[0051] A lifting shovel mechanism 21 is provided in the operation area 2, and the lifting shovel mechanism 21 can grab and transport the sample box.

[0052] Preferably, the lifting shovel mechanism 21 can be raised and lowered, and can also adjust the horizontal angle.

[0053] Furthermore, the lifting shovel mechanism 21 includes an angle adjustment component and a grabbing component; the angle adjustment component can perform at least one level of rotation, and a grabbing component is arranged on the angle adjustment component, the angle adjustment component can drive the grabbing component to turn, and the grabbing component can scoop and store the sample box inside the sample storage cabin 1.

[0054] Preferably, the angle adjustment component can drive the grabbing component to change its angle; the grabbing component can be used to scoop up the sample box and clamp the sample box to prevent the sample box from falling off during transportation.

[0055] Furthermore, the grabbing assembly includes a supporting telescopic member 2121 and a grabbing member 2122 ; the supporting telescopic member 2121 can drive the grabbing member 2122 to move horizontally, and the sample box can be scooped through the grabbing member 2122 .

[0056] Furthermore, the grabbing assembly further includes a guide and limit frame 2123 , which is connected to the supporting telescopic member 2121 , and the guide and limit frame 2123 can clamp the grabbing member 2122 .

[0057] Preferably, the supporting telescopic member 2121 can drive the grabbing member 2122 to move horizontally, and the sample box grabbed by the grabbing member 2122 can be brought into the guiding limit frame 2123 through the supporting telescopic member 2121, and the grabbing member 2122 can be squeezed and limited by the guiding limit frame 2123, so that the grabbing member 2122 clamps the sample box.

[0058] Furthermore, the supporting telescopic member 2121 includes a supporting plate 21211, a first driving member 21212, and a first follower 21213; one end of the supporting plate 21211 is connected to the angle adjustment assembly, the first driving member 21212 is arranged on the supporting plate 21211, the first follower 21213 is arranged on the side of the first driving member 21212, the front end of the first follower 21213 is connected to the grabbing member 2122, the first driving member 21212 can drive the first follower 21213 to move horizontally along the supporting plate 21211, and the first follower 21213 can drive the grabbing member 2122 to move horizontally.

[0059] Preferably, the first driving member 21212 includes a motor and a gear, and the first follower 21213 is a spur plate. The gear can drive the spur plate to move forward and backward, and the spur plate moves horizontally along the support plate 21211, and the support plate 21211 can support and guide the spur plate.

[0060] Furthermore, the grabbing member 2122 includes a supporting jaw 21221, an elastic telescopic member 21222, and a guide end 21223; the first follower member 21213 is respectively provided with elastic telescopic members 21222 on both sides of the front end, the side of the elastic telescopic member 21222 is provided with a supporting jaw 21221, and the outer side of the supporting jaw 21221 is provided with a guide end 21223, and the guide end 21223 can guide the supporting jaw 21221 to enter the guide limit frame 2123.

[0061] Preferably, the supporting jaws 21221 can scoop up the sample box and support the sample box. After the supporting jaws 21221 grab the sample box, the first follower member 21213 is driven by the first driving member 21212 to drive the grabbing member 2122 to enter the guide limit frame 2123, and the guide end 21223 first contacts the guide limit frame 2123, and then the guide limit frame 2123 squeezes the supporting jaws 21221, so that the supporting jaws 21221 squeeze the elastic telescopic member 21222, so that the two groups of supporting jaws 21221 move toward the middle, so that the supporting jaws 21221 clamp the sample box.

[0062] Preferably, after reaching the transfer position, when the sample box needs to be placed in a specified position, the first drive member 21212 drives the first follower member 21213 to drive the grasping member 2122 to disengage from the guide limit frame 2123, and under the action of the elastic telescopic member 21222, the two groups of supporting jaws 21221 move away from each other. At this time, the two groups of supporting jaws 21221 cancel the limit on the sample box and can be placed in a specific position.

[0063] Preferably, the elastic telescopic member 21222 can adopt a pin and a spring, and a spring is arranged on the pin. Of course, the elastic device of the prior art can also be adopted, as long as it can make the supporting jaws 21221 move away from each other or towards each other.

[0064] Furthermore, the two groups of supporting jaws 21221 can move away from each other or towards each other, and the supporting jaws 21221 can clamp or release the plate rack.

[0065] Furthermore, the first follower 21213 can pass through the guide limit frame 2123 to be connected with the grabbing member 2122 .

[0066] Furthermore, the angle adjustment component includes a primary rotating part, a secondary rotating part, and a tertiary rotating part; the primary rotating part and the tertiary rotating part are respectively connected to the two sides of the secondary rotating part, one end of the tertiary rotating part is connected to the grasping component, and the primary rotating part, the secondary rotating part, and the tertiary rotating part can all rotate at different angles.

[0067] Preferably, the primary rotating member can rotate on the vertical driving mechanism 213, the secondary rotating member can rotate around the primary rotating member, and the tertiary rotating member can rotate around the secondary rotating member, thereby achieving more conversion angles and a wider range of adaptability.

[0068] Furthermore, it also includes a vertical driving mechanism 213, on which an angle adjustment component is arranged. The vertical driving mechanism 213 can drive the angle adjustment component and the grabbing component to move up and down.

[0069] Preferably, by providing a vertical driving mechanism 213 , the sample boxes on each vertical layer of the rotating storage rack assembly 11 can be scooped.

[0070] Furthermore, the refrigeration mechanism 3 is a compressor refrigeration mechanism 31 ; the compressor refrigeration mechanism 31 is arranged at a side end of the sample storage compartment 1 .

[0071] Preferably, the samples in the sample storage compartment 1 can be frozen by compressor refrigeration.

[0072] Furthermore, a ventilation mechanism 33 is provided in the compressor refrigeration mechanism 31, and the ventilation mechanism 33 can ventilate the compressor refrigeration mechanism 31. The compressor refrigeration mechanism 31 is also provided with a maintenance port, through which the compressor refrigeration mechanism 31 can be maintained.

[0073] Preferably, the heat generated by the compressor refrigeration mechanism 31 can be transported out through the ventilation mechanism 33; and the compressor refrigeration mechanism 31 can be conveniently maintained through the maintenance port.

[0074] Furthermore, the ventilation mechanism 33 includes an exhaust member 331 and a pipe 332 ; the exhaust member 331 is disposed in the pipe 332 , one end of the pipe 332 is connected to the compressor refrigeration mechanism 31 , and the other end passes through the operating area 2 and leads to the outside of the operating area 2 .

[0075] Furthermore, a revolving door assembly 4 is provided on the sample storage cabin 1, and the revolving door assembly 4 is arranged inside the operating area 2, and the revolving door assembly 4 can open and close the scooping channel.

[0076] Preferably, when the revolving door assembly 4 is in an open state for the scooping channel, the lifting shovel mechanism 21 can scoop the sample box in the sample storage cabin 1 through the scooping channel; when the revolving door assembly 4 is in a closed state for the scooping channel, the sample storage cabin 1 and the operating area 2 are isolated, and the lifting shovel mechanism 21 cannot scoop the sample box in the sample storage cabin 1.

[0077] Furthermore, the revolving door assembly 4 includes a revolving door driving member 41 and a revolving door 42; the lower end of the revolving door driving member 41 is connected to the revolving door 42, and the revolving door driving member 41 can drive the revolving door 42 to open and close the scooping channel.

[0078] Furthermore, a rotatable storage rack assembly 11 is provided in the sample storage compartment 1, and the rotatable storage rack assembly 11 can store and retrieve the sample boxes.

[0079] Preferably, by providing a rotatable rotating storage rack assembly 11, it can cooperate with the lifting shovel mechanism 21, so that the sample boxes on each vertical column and each horizontal column of the rotating storage rack assembly 11 can be scooped.

[0080] Furthermore, a transfer port is provided at the side of the operation area 2, and a transfer door 29 is provided in the transfer port. The transfer door 29 can open and close the transfer port.

[0081] Preferably, after the transfer door 29 is opened, the sample box can be transferred from the outside to the operation area 2 through the transfer port to perform tube picking or sample storage work.

[0082] Furthermore, a code scanning mechanism 5 is provided on the side of the transfer door 29, and the code scanning mechanism 5 can scan the sample box.

[0083] Furthermore, a storage compartment inspection port is provided on the sample storage compartment 1 , and an inspection door 7 is provided in the storage compartment inspection port. The inspection door 7 can be opened and closed for the storage compartment inspection port. When the inspection door 7 is opened, the interior of the sample storage compartment 1 can be inspected.

[0084] Preferably, by providing the inspection door 7, when a fault occurs inside the sample storage chamber 1, the inspection door 7 can be quickly opened for maintenance, and the fast-rotating storage rack assembly 11 can be repaired.

[0085] Furthermore, a display control device 8 is also provided on the sample storage cabin 1, and the display control device 8 can display the internal parameters of the sample storage cabin 1 and adjust the control work.

[0086] Preferably, by providing a display control device 8, commands can be issued to make the device work, and the progress of each device can be displayed in real time, such as displaying the internal temperature, or displaying the position of the sample box on the rotating storage rack assembly 11, etc.

[0087] In summary, the present invention can scoop and transport the sample boxes in the sample storage cabin 1 through the rotating door assembly 4 through the lifting shovel mechanism 21, which can improve the efficiency of scooping the sample boxes. The lifting shovel mechanism 21 can scoop and clamp the samples to ensure that the sample boxes will not fall off during the transportation process; by providing the inspection door 7, the rotating storage rack assembly 11 inside the sample storage cabin 1 can be quickly maintained.

[0088] Example 2

[0089] Reference Figures 5 to 14 , which is the second embodiment of the present invention. In the previous embodiment, the biological sample low-temperature storage refrigerator includes a sample storage cabin 1, an operation area 2, and a refrigeration mechanism 3; the sample storage cabin 1 is provided with a refrigeration mechanism 3, and the sample in the sample storage cabin 1 can be low-temperature frozen by the refrigeration mechanism 3, and the side of the sample storage cabin 1 is provided with an operation area 2, and the sample box in the sample storage cabin 1 can be scooped, transported, and picked up by the operation area 2.

[0090] Specifically, the sample storage cabin 1, the operation area 2, and the refrigeration mechanism 3; the side of the sample storage cabin 1 is provided with the operation area 2, and the sample storage cabin 1 is provided with the refrigeration mechanism 3, and the refrigeration mechanism 3 can refrigerate the sample storage cabin 1; the operation area 2 can store and retrieve the samples in the sample storage cabin 1, and the sample storage cabin 1 can store the basket samples;

[0091] A lifting shovel mechanism 21 is provided in the operation area 2, and the lifting shovel mechanism 21 can grab and transport the sample box.

[0092] Preferably, the lifting shovel mechanism 21 can be raised and lowered, and the horizontal angle can also be adjusted.

[0093] Furthermore, the lifting shovel mechanism 21 includes an angle adjustment component and a grabbing component; the angle adjustment component can perform at least one level of rotation, and a grabbing component is arranged on the angle adjustment component, the angle adjustment component can drive the grabbing component to turn, and the grabbing component can scoop and store the sample box inside the sample storage cabin 1.

[0094] Preferably, the angle adjustment component can drive the grabbing component to change its angle; the grabbing component can be used to scoop up the sample box and clamp the sample box to prevent the sample box from falling off during transportation.

[0095] Furthermore, the grabbing assembly includes a supporting telescopic member 2121 and a grabbing member 2122 ; the supporting telescopic member 2121 can drive the grabbing member 2122 to move horizontally, and the sample box can be scooped through the grabbing member 2122 .

[0096] Furthermore, the grabbing assembly further includes a guide and limit frame 2123 , which is connected to the supporting telescopic member 2121 , and the guide and limit frame 2123 can clamp the grabbing member 2122 .

[0097] Preferably, the supporting telescopic member 2121 can drive the grabbing member 2122 to move horizontally, and the sample box grabbed by the grabbing member 2122 can be brought into the guiding limit frame 2123 through the supporting telescopic member 2121, and the grabbing member 2122 can be squeezed and limited by the guiding limit frame 2123, so that the grabbing member 2122 clamps the sample box.

[0098] Furthermore, the supporting telescopic member 2121 includes a supporting plate 21211, a first driving member 21212, and a first follower 21213; one end of the supporting plate 21211 is connected to the angle adjustment assembly, the first driving member 21212 is arranged on the supporting plate 21211, the first follower 21213 is arranged on the side of the first driving member 21212, the front end of the first follower 21213 is connected to the grabbing member 2122, the first driving member 21212 can drive the first follower 21213 to move horizontally along the supporting plate 21211, and the first follower 21213 can drive the grabbing member 2122 to move horizontally.

[0099] Preferably, the first driving member 21212 includes a motor and a gear, and the first follower 21213 is a spur plate. The gear can drive the spur plate to move forward and backward, and the spur plate moves horizontally along the support plate 21211, and the support plate 21211 can support and guide the spur plate.

[0100] Furthermore, the grabbing member 2122 includes a supporting jaw 21221, an elastic telescopic member 21222, and a guide end 21223; the first follower member 21213 is respectively provided with elastic telescopic members 21222 on both sides of the front end, the side of the elastic telescopic member 21222 is provided with a supporting jaw 21221, and the outer side of the supporting jaw 21221 is provided with a guide end 21223, and the guide end 21223 can guide the supporting jaw 21221 to enter the guide limit frame 2123.

[0101] Preferably, the supporting jaws 21221 can scoop up the sample box and support the sample box. After the supporting jaws 21221 grab the sample box, the first follower member 21213 is driven by the first driving member 21212 to drive the grabbing member 2122 to enter the guide limit frame 2123, and the guide end 21223 first contacts the guide limit frame 2123, and then the guide limit frame 2123 squeezes the supporting jaws 21221, so that the supporting jaws 21221 squeeze the elastic telescopic member 21222, so that the two groups of supporting jaws 21221 move toward the middle, so that the supporting jaws 21221 clamp the sample box.

[0102] Preferably, after reaching the transfer position, when the sample box needs to be placed in a specified position, the first drive member 21212 drives the first follower member 21213 to drive the grasping member 2122 to disengage from the guide limit frame 2123, and under the action of the elastic telescopic member 21222, the two groups of supporting jaws 21221 move away from each other. At this time, the two groups of supporting jaws 21221 cancel the limit on the sample box and can be placed in a specific position.

[0103] Preferably, the elastic telescopic member 21222 can adopt a pin and a spring, and a spring is arranged on the pin. Of course, the elastic device of the prior art can also be adopted, as long as it can make the supporting jaws 21221 move away from each other or towards each other.

[0104] Furthermore, the two groups of supporting jaws 21221 can move away from each other or towards each other, and the supporting jaws 21221 can clamp or release the plate rack.

[0105] Furthermore, the first follower 21213 can pass through the guide limit frame 2123 to be connected with the grabbing member 2122 .

[0106] Furthermore, the angle adjustment component includes a primary rotating part, a secondary rotating part, and a tertiary rotating part; the primary rotating part and the tertiary rotating part are respectively connected to the two sides of the secondary rotating part, one end of the tertiary rotating part is connected to the grasping component, and the primary rotating part, the secondary rotating part, and the tertiary rotating part can all rotate at different angles.

[0107] Preferably, the primary rotating member can rotate on the vertical driving mechanism 213, the secondary rotating member can rotate around the primary rotating member, and the tertiary rotating member can rotate around the secondary rotating member, thereby achieving more conversion angles and a wider range of adaptability.

[0108] Furthermore, it also includes a vertical driving mechanism 213, on which an angle adjustment component is arranged. The vertical driving mechanism 213 can drive the angle adjustment component and the grabbing component to move up and down.

[0109] Preferably, by providing a vertical driving mechanism 213 , the sample boxes on each vertical layer of the rotating storage rack assembly 11 can be scooped.

[0110] Furthermore, the refrigeration mechanism 3 is a Stirling refrigeration mechanism 32 , and the Stirling refrigeration mechanism 32 is arranged at the upper end of the sample storage compartment 1 .

[0111] Preferably, the Stirling refrigeration mechanism 32 can significantly save liquid nitrogen, and the liquid nitrogen can be recycled, thereby reducing the cost of use.

[0112] Furthermore, the Stirling refrigeration mechanism 32 includes a Stirling refrigeration module 321, a cold head 322, and a storage cavity 323; the lower end of the Stirling refrigeration module 321 is connected to the cold head 322, the storage cavity 323 is detachably connected to the Stirling refrigeration module 321, and the cold head 322 is arranged inside the storage cavity 323, liquid nitrogen can be stored in the storage cavity 323, and the cold head 322 can liquefy the vaporized nitrogen.

[0113] Preferably, the storage cavity 323 can be circular, cylindrical or other irregular shapes; and different types of storage cavities 323 can be docked with the Stirling refrigeration module 321 and the cold head 322. The storage cavity 323 and the Stirling refrigeration module 321 are detachably connected, so that different types of storage cavities 323 can be easily replaced.

[0114] Preferably, only a certain amount of liquid nitrogen needs to be placed in the storage chamber 323 for the first time. The liquid nitrogen will be vaporized into nitrogen in the storage chamber 323, and the nitrogen will rise into the cold head 322. After being cooled by the Stirling refrigeration module 321 and the cold head 322, the nitrogen can be converted into liquid nitrogen and flow into the storage chamber 323 again. Then, the vaporization and liquefaction operations are performed again to achieve a cycle, and there is zero loss of liquid nitrogen, which greatly saves the use of liquid nitrogen and reduces the cost of liquid nitrogen.

[0115] Furthermore, a revolving door assembly 4 is provided on the sample storage cabin 1, and the revolving door assembly 4 is arranged inside the operating area 2, and the revolving door assembly 4 can open and close the scooping channel.

[0116] Preferably, when the revolving door assembly 4 is in an open state for the scooping channel, the lifting shovel mechanism 21 can scoop the sample box in the sample storage cabin 1 through the scooping channel; when the revolving door assembly 4 is in a closed state for the scooping channel, the sample storage cabin 1 and the operating area 2 are isolated, and the lifting shovel mechanism 21 cannot scoop the sample box in the sample storage cabin 1.

[0117] Furthermore, the revolving door assembly 4 includes a revolving door driving member 41 and a revolving door 42; the lower end of the revolving door driving member 41 is connected to the revolving door 42, and the revolving door driving member 41 can drive the revolving door 42 to open and close the scooping channel.

[0118] Furthermore, a rotatable storage rack assembly 11 is provided in the sample storage compartment 1, and the rotatable storage rack assembly 11 can store and retrieve the sample boxes.

[0119] Preferably, by providing a rotatable rotating storage rack assembly 11, it can cooperate with the lifting shovel mechanism 21, so that the sample boxes on each vertical column and each horizontal column of the rotating storage rack assembly 11 can be scooped.

[0120] Furthermore, a transfer port is provided at the side of the operation area 2, and a transfer door 29 is provided in the transfer port. The transfer door 29 can open and close the transfer port.

[0121] Preferably, after the transfer door 29 is opened, the sample box can be transferred from the outside to the operation area 2 through the transfer port to perform tube picking or sample storage work.

[0122] Furthermore, a code scanning mechanism 5 is provided on the side of the transfer door 29, and the code scanning mechanism 5 can scan the sample box.

[0123] Furthermore, a storage compartment inspection port is provided on the sample storage compartment 1 , and an inspection door 7 is provided in the storage compartment inspection port. The inspection door 7 can be opened and closed for the storage compartment inspection port. When the inspection door 7 is opened, the interior of the sample storage compartment 1 can be inspected.

[0124] Preferably, by providing the inspection door 7, when a fault occurs inside the sample storage chamber 1, the inspection door 7 can be quickly opened for maintenance, and the fast-rotating storage rack assembly 11 can be repaired.

[0125] Furthermore, a display control device 8 is also provided on the sample storage cabin 1, and the display control device 8 can display the internal parameters of the sample storage cabin 1 and adjust the control work.

[0126] Preferably, by providing a display control device 8, commands can be issued to make the device work, and the progress of each device can be displayed in real time, such as displaying the internal temperature, or displaying the position of the sample box on the rotating storage rack assembly 11, etc.

[0127] In summary, the present invention can realize the automatic adjustable technology of 5 to -150 degrees by providing a liquid storage tank at the bottom of the Stirling refrigeration mechanism 32 and injecting a certain amount of liquid nitrogen at one time and sealing it; a certain amount of liquid nitrogen is added into the storage cavity 323 at one time and sealed, and the Stirling refrigeration mechanism 32 is turned on, and the cold head 322 at one end of the Stirling refrigeration mechanism 32 generates a cold source, and the liquid nitrogen in the storage cavity 323 is gasified and rises to one end of the cold head 322 of the Stirling, and is cooled and liquefied by the cold head 322 of the Stirling refrigeration mechanism 32, and the liquid is automatically stored, and the automatic operation is repeated over and over again to achieve the effect of balanced cold conduction and refrigeration; a high-pressure cold head 322 and a high-pressure stainless steel shaft storage cavity 323 are used to form a high-pressure cavity without pressure relief; due to the high-pressure boiling point difference, the liquefaction ability of the liquid is improved, and the liquid sinks quickly and is evenly cooled; one-time liquid addition, lifelong use, no matter whether the power is turned on or stored, the gasified gas such as liquid nitrogen is automatically compressed in the cavity without affecting safe long-term storage; it is very easy to replace and upgrade and easy to clean and disinfect; low power consumption and energy saving of 50%.

[0128] Importantly, it should be noted that the construction and arrangement of the present application shown in a plurality of different exemplary embodiments are only exemplary. Although only a few embodiments are described in detail in this disclosure, it should be readily understood by those who refer to this disclosure that many modifications are possible (e.g., the size, scale, structure, shape and proportion of various elements, and parameter values ​​(e.g., temperature, pressure, etc.), installation arrangement, use of materials, color, directional changes, etc.) without substantially departing from the novel teachings and advantages of the subject matter described in the application. For example, the element shown as integrally formed can be composed of multiple parts or elements, the position of the element can be inverted or otherwise changed, and the nature or number or position of the discrete element can be changed or changed. Therefore, all such modifications are intended to be included in the scope of the present invention. The order or sequence of any process or method steps can be changed or reordered according to alternative embodiments. In the claims, any "device plus function" clause is intended to cover the structure of performing the function described herein, and is not only structurally equivalent but also equivalent structure. Without departing from the scope of the present invention, other replacements, modifications, changes and omissions can be made in the design, operating conditions and arrangement of the exemplary embodiments. Therefore, the invention is not limited to a specific embodiment, but extends to numerous modifications still falling within the scope of the appended claims.

[0129] Additionally, in order to provide a concise description of exemplary embodiments, all features of an actual embodiment (ie, those features that are not relevant to the best mode presently contemplated for carrying out the invention or those that are not relevant to implementing the invention) may not be described.

[0130] It will be appreciated that in the development of any actual implementation, as in any engineering or design project, numerous implementation-specific decisions may be made. Such a development effort may be complex and time-consuming, but will be a routine task of design, fabrication, and production for those of ordinary skill having the benefit of this disclosure without undue experimentation.

[0131] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present invention may be modified or replaced by equivalents without departing from the spirit and scope of the technical solutions of the present invention, which should all be included in the scope of the claims of the present invention.

Claims

1. A biological sample low-temperature storage refrigerator, characterized in that: The sample storage chamber (1) comprises a sample storage chamber (1), an operation area (2), and a refrigeration mechanism (3); the sample storage chamber (1) is provided with an operation area (2) on its side, the sample storage chamber (1) is provided with a refrigeration mechanism (3), and the refrigeration mechanism (3) can refrigerate the sample storage chamber (1); the operation area (2) can store and retrieve samples in the sample storage chamber (1), and the sample storage chamber (1) can store basket samples; A lifting shovel mechanism (21) is provided in the operation area (2), and the lifting shovel mechanism (21) can grab and transport the sample box.

2. The biological sample low-temperature storage refrigerator according to claim 1, characterized in that: The lifting shovel mechanism (21) includes an angle adjustment component and a grabbing component; the angle adjustment component can perform at least one level of rotation, and a grabbing component is arranged on the angle adjustment component. The angle adjustment component can drive the grabbing component to turn, and the grabbing component can scoop and store the sample box inside the sample storage chamber (1).

3. The biological sample low-temperature storage refrigerator according to claim 2, characterized in that: The grabbing assembly comprises a supporting telescopic member (2121) and a grabbing member (2122); the supporting telescopic member (2121) can drive the grabbing member (2122) to move horizontally, and the sample box can be scooped through the grabbing member (2122).

4. The biological sample low-temperature storage refrigerator according to claim 3, characterized in that: The grabbing assembly further comprises a guide and limit frame (2123), wherein the guide and limit frame (2123) is connected to the supporting telescopic member (2121), and the guide and limit frame (2123) can clamp the grabbing member (2122).

5. The biological sample low-temperature storage refrigerator according to claim 4, characterized in that: The supporting telescopic member (2121) comprises a supporting plate (21211), a first driving member (21212), and a first follower (21213); one end of the supporting plate (21211) is connected to the angle adjustment component, the first driving member (21212) is arranged on the supporting plate (21211), the first follower (21213) is arranged on the side of the first driving member (21212), the front end of the first follower (21213) is connected to the grabbing member (2122), the first driving member (21212) can drive the first follower (21213) to move horizontally along the supporting plate (21211), and the first follower (21213) can drive the grabbing member (2122) to move horizontally.

6. The biological sample low-temperature storage refrigerator according to claim 5, characterized in that: The grasping member (2122) comprises a supporting clamp (21221), an elastic telescopic member (21222), and a guide end (21223); the first follower member (21213) is provided with elastic telescopic members (21222) on both sides of the front end, the supporting clamp (21221) is provided on the side of the elastic telescopic member (21222), and the outer side of the supporting clamp (21221) is provided with a guide end (21223), and the guide end (21223) can guide the supporting clamp (21221) to enter the guide limit frame (2123).

7. The biological sample low-temperature storage refrigerator according to claim 6, characterized in that: The two groups of support clamps (21221) can move away from each other or towards each other, and the support clamps (21221) can clamp or release the plate frame.

8. The biological sample low-temperature storage refrigerator according to claim 5, characterized in that: The first follower (21213) can pass through the guide limit frame (2123) to be connected with the grabbing member (2122).

9. The biological sample low-temperature storage refrigerator according to claim 2, characterized in that: The angle adjustment component includes a primary rotating part, a secondary rotating part, and a tertiary rotating part; the two sides of the secondary rotating part are respectively connected to the primary rotating part and the tertiary rotating part, one end of the tertiary rotating part is connected to the grabbing component, and the primary rotating part, the secondary rotating part, and the tertiary rotating part can all rotate at different angles.

10. The biological sample low-temperature storage refrigerator according to claim 2, characterized in that: It also comprises a vertical driving mechanism (213), on which an angle adjustment component is arranged, and the vertical driving mechanism (213) can drive the angle adjustment component and the grabbing component to move up and down.

11. The biological sample low-temperature storage refrigerator according to any one of claims 1 to 10, characterized in that: The refrigeration mechanism (3) is a compressor refrigeration mechanism (31) or a Stirling refrigeration mechanism (32); the Stirling refrigeration mechanism (32) is arranged at the upper end of the sample storage compartment (1); and the compressor refrigeration mechanism (31) is arranged at the side end of the sample storage compartment (1).

12. The biological sample low-temperature storage refrigerator according to claim 11, characterized in that: The compressor refrigeration mechanism (31) is provided with a ventilation mechanism (33), and the ventilation mechanism (33) can ventilate the compressor refrigeration mechanism (31). The compressor refrigeration mechanism (31) is also provided with a maintenance port, and the compressor refrigeration mechanism (31) can be maintained through the maintenance port.

13. The biological sample low-temperature storage refrigerator according to claim 12, characterized in that: The ventilation mechanism (33) comprises an exhaust member (331) and a pipe (332); the exhaust member (331) is arranged in the pipe (332); one end of the pipe (332) is connected to the compressor refrigeration mechanism (31), and the other end passes through the operating area (2) and leads to the outside of the operating area (2).

14. The biological sample low-temperature storage refrigerator according to claim 11, characterized in that: The Stirling refrigeration mechanism (32) comprises a Stirling refrigeration module (321), a cold head (322), and a storage cavity (323); the lower end of the Stirling refrigeration module (321) is connected to the cold head (322), the storage cavity (323) and the Stirling refrigeration module (321) are detachably connected, and the cold head (322) is arranged inside the storage cavity (323); liquid nitrogen can be stored in the storage cavity (323), and the cold head (322) can liquefy vaporized nitrogen.

15. The biological sample low-temperature storage refrigerator according to any one of claims 1 to 10, characterized in that: The sample storage cabin (1) is also provided with a revolving door assembly (4), and the revolving door assembly (4) is arranged inside the operating area (2), and the revolving door assembly (4) can open and close the scooping channel.

16. The biological sample low-temperature storage refrigerator according to claim 15, characterized in that: The revolving door assembly (4) comprises a revolving door driving member (41) and a revolving door (42); the lower end of the revolving door driving member (41) is connected to the revolving door (42), and the revolving door driving member (41) can drive the revolving door (42) to open and close the scooping channel.

17. The biological sample low-temperature storage refrigerator according to any one of claims 1 to 10, characterized in that: A rotatable storage rack assembly (11) is arranged in the sample storage compartment (1), and the rotatable storage rack assembly (11) can store and retrieve sample boxes.

18. The biological sample low-temperature storage refrigerator according to any one of claims 1 to 10, characterized in that: A transfer port is arranged on the side of the operation area (2), and a transfer door (29) is arranged in the transfer port. The transfer door (29) can be opened and closed by the transfer port.

19. The biological sample low-temperature storage refrigerator according to claim 18, characterized in that: A code scanning mechanism (5) is arranged on the side of the transfer door (29), and the code scanning mechanism (5) can scan the code of the sample box.

20. The biological sample low-temperature storage refrigerator according to claim 17, characterized in that: The sample storage compartment (1) is provided with a storage compartment inspection opening, and an inspection door (7) is arranged inside the storage compartment inspection opening. The inspection door (7) can be opened and closed to inspect the interior of the sample storage compartment (1).

21. The biological sample low-temperature storage refrigerator according to claim 20, characterized in that: The sample storage chamber (1) is also provided with a display control device (8), and the display control device (8) can display the internal parameters of the sample storage chamber (1) and adjust the control work.

Citation Information

Patent Citations

  • Full-automatic sample low-temperature storing and taking system

    CN116409573A