Medicinal and edible formula for resisting cold and enhancing immunity

Abstract

The invention discloses a medicinal and edible formula for resisting cold and enhancing immunity. The invention belongs to the technical field of medicine and food, according to the theory of traditional Chinese medicine, a plurality of medicine and food homologous raw materials with the effects of resisting cold and enhancing immunity are selected for scientific compatibility; the raw materials used in the traditional Chinese medicine composition cooperate with each other, so that the traditional Chinese medicine composition not only can effectively prevent cold, but also can relieve symptoms and promote physical rehabilitation during a cold period, and meanwhile, can improve organism immunity and enhance defense capability of organisms to various diseases after being taken for a long time; the health-care food adopts medicinal and edible raw materials, is high in safety, has no obvious toxic or side effect, is suitable for people of different ages to take for a long time, and is used as a functional food or health-care product for daily health care and cold prevention; the preparation method is simple and easy to implement, can be prepared into different oral dosage forms according to actual requirements, and is convenient to produce, store, transport and take.

Description

Technical Field

[0001] The invention belongs to the technical field of medicine and food, and specifically refers to a medicine and food homologous formula for resisting cold and enhancing immunity. Background Art

[0002] As one of the most common respiratory diseases, colds have a very high incidence rate worldwide. According to relevant medical statistics, adults catch colds an average of 2-5 times a year, and children catch them even more frequently. This not only poses a direct threat to personal health, causing a series of uncomfortable symptoms such as fever, cough, nasal congestion, runny nose, fatigue, etc., seriously affecting daily life, learning and work efficiency, but also in some special groups such as the elderly, children, people with low immunity and people with chronic underlying diseases, colds may also cause more serious complications such as pneumonia and bronchitis, which significantly increases the medical burden and may endanger life safety.

[0003] When dealing with colds, modern medicine mainly focuses on relieving and treating specific symptoms. For example, when patients have fever symptoms, antipyretics are often used to lower body temperature; when cough symptoms are obvious, cough suppressants are used to suppress cough; for nasal congestion and runny nose, antihistamines or decongestants are often used to improve nasal ventilation. However, this symptomatic treatment method can often only relieve the patient's pain in the short term, and there is no specific direct treatment for the root cause of the cold - viral infection. In addition, modern medicine provides relatively limited effective intervention measures in preventing colds and comprehensively enhancing the body's own immunity to resist viral invasion.

[0004] In contrast, TCM theory has a long history, and its concept of "preventing illness before it occurs" contains profound preventive medical ideas. TCM believes that the human body is an organic whole, and the balance of yin and yang is the key to maintaining health. Once the yin and yang are out of balance, external evils (such as wind-cold, wind-heat and other pathogenic factors that cause colds) can easily take advantage of the situation and enter. By using a variety of methods such as Chinese medicine, acupuncture, massage, and diet therapy to adjust the balance of yin and yang in the human body, strengthen the body and eliminate evil, diseases can be effectively prevented and treated.

[0005] Among them, the concept of medicine and food homology occupies an extremely important position in the field of TCM health care. Many natural food ingredients and Chinese medicinal materials have been found to have both nutritional and medicinal values ​​in the long history of practice. For example, in traditional Chinese medicine classics and folk experience, many foods are widely used in daily health care and disease prevention. These medicine and food homology substances contain rich bioactive ingredients, such as polysaccharides, flavonoids, volatile oils, vitamins, minerals, etc. They can act on the human immune system from multiple levels, including promoting the generation and differentiation of immune cells, enhancing the activity of immune cells, regulating the secretion and balance of immune factors, etc., thereby enhancing the overall immune function of the body and making it more capable of resisting the invasion of external pathogens. At the same time, when a cold occurs, some medicine and food homology raw materials can also rely on their special pharmacological effects, such as antiviral, antibacterial, anti-inflammatory, and antipyretic effects, to alleviate cold symptoms and promote the body's recovery process. Reasonable combination of these medicine and food homology raw materials can give full play to the synergistic effect between them, providing a very potential way to develop safe, effective, and long-term anti-cold and immunity-enhancing products. Summary of the invention

[0006] The purpose of the present invention is to provide a medicine-food formula for resisting colds and enhancing immunity. The medicine-food formula of the present invention is based on the theory of traditional Chinese medicine, selects a variety of medicine-food raw materials with the effects of resisting colds and enhancing immunity for scientific compatibility, and the raw materials work together, which can not only effectively prevent the occurrence of colds, but also relieve symptoms during colds and promote physical recovery. At the same time, long-term use can improve the body's immunity and enhance the body's defense ability against various diseases; the formula adopts medicine-food raw materials, has high safety, has no obvious toxic and side effects, is suitable for long-term use by people of different ages, and is used as a functional food or health product for daily health care and prevention of colds; the preparation method is simple and easy, and can be made into different oral dosage forms according to actual needs, which is convenient for production, storage, transportation and use.

[0007] In order to achieve the above-mentioned purpose, the technical scheme adopted by the present invention is as follows: a medicine-food formula for resisting colds and enhancing immunity, the medicine-food formula comprising the following components in parts by weight: 5-90 grams of astragalus or its extract; 5-90 grams of ginseng or its extract; 5-90 grams of perilla leaf or its extract; 10-90 grams of purslane or its extract; 5-60 grams of honeysuckle or its extract; 5-60 grams of kudzu root or its extract; 5-60 grams of salvia miltiorrhiza or its extract; 5-60 grams of epimedium or its extract; 5-60 grams of ophiopogon or its extract; 5-60 grams of licorice or its extract; 5-60 grams of schisandra or its extract; 5-60 grams of polygonatum or its extract; 5-60 grams of rehmannia root or its extract; 5-60 grams of atractylodes or its extract.

[0008] Preferably, the medicine-food formula includes the following components in parts by weight: 10-70 grams of astragalus or its extract; 20-80 grams of ginseng or its extract; 5-70 grams of perilla leaf or its extract; 20-80 grams of purslane or its extract; 15-60 grams of honeysuckle or its extract; 10-50 grams of kudzu root or its extract; 10-60 grams of salvia miltiorrhiza or its extract; 10-60 grams of epimedium or its extract; 20-50 grams of ophiopogon or its extract; 10-50 grams of licorice or its extract; 15-60 grams of schisandra or its extract; 10-50 grams of polygonatum or its extract; 20-50 grams of rehmannia root or its extract; 10-60 grams of atractylodes or its extract.

[0009] Preferably, the medicine-food formula includes the following components in parts by weight: 20-40 grams of Astragalus or its extract; 30-50 grams of Ginseng or its extract; 10-50 grams of Perilla leaf or its extract; 30-50 grams of Portulaca oleracea or its extract; 20-40 grams of Honeysuckle or its extract; 20-40 grams of Pueraria or its extract; 10-30 grams of Salvia miltiorrhiza or its extract; 20-40 grams of Epimedium or its extract; 30-50 grams of Ophiopogon or its extract; 10-30 grams of Licorice or its extract; 20-60 grams of Schisandra or its extract; 20-40 grams of Polygonatum sibiricum or its extract; 30-40 grams of Rehmannia glutinosa or its extract; 20-40 grams of Atractylodes macrocephala or its extract.

[0010] The present invention also provides a method for preparing a medicine-food formula for resisting colds and enhancing immunity, the preparation method comprising the following steps:

[0011] (1) taking the above-mentioned Chinese medicinal raw materials by weight, washing them and drying them;

[0012] (2) placing the mixed raw materials in a container and adding water to soak them;

[0013] (3) First, boil the water over high heat, then simmer over low heat for 30-60 minutes, filter, and obtain the first decoction;

[0014] (4) adding 3-5 times the amount of water to the filter residue, decocting for a second time according to the above decoction method, filtering, and obtaining a second decoction liquid;

[0015] (5) combining the two decoctions and concentrating them into an extract with a relative density of 1.05-1.15;

[0016] (6) Drying and crushing the extract to prepare a powder.

[0017] Furthermore, the weight of water in step (2) is 5-10 times the total weight of the raw materials.

[0018] Furthermore, the soaking time in step (2) is 1-2 hours.

[0019] Furthermore, the temperature condition of relative density in step (5) is 60-70°C.

[0020] Furthermore, in step (6), appropriate auxiliary materials such as starch, dextrin, etc. can be added to prepare oral dosage forms such as granules, tablets or capsules.

[0021] The beneficial effects achieved by the present invention using the above structure are as follows: (1) The food-medicine formula of the present invention is based on the theory of traditional Chinese medicine, and a variety of food-medicine raw materials with anti-cold and immunity-enhancing effects are scientifically combined; (2) The raw materials used in the present invention work together to effectively prevent the occurrence of colds, relieve symptoms during colds, and promote physical recovery. At the same time, long-term use can improve the body's immunity and enhance the body's defense against various diseases; (3) The present invention uses food-medicine raw materials with high safety and no obvious toxic and side effects. It is suitable for long-term use by people of different ages as a functional food or health product for daily health care and prevention of colds; (4) The preparation method of the present invention is simple and easy to implement, and can be made into different oral dosage forms according to actual needs, which is convenient for production, storage, transportation and use. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 Mouse immune organ index.

[0023] The accompanying drawings are used to provide further understanding of the present invention and constitute a part of the specification. They are used to explain the present invention together with the embodiments of the present invention and do not constitute a limitation of the present invention. DETAILED DESCRIPTION

[0024] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments; based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0025] Unless otherwise defined, all professional and scientific terms used herein have the same meanings as those familiar to those skilled in the art. In addition, any methods and materials similar or equivalent to those described herein may be applied to the present invention. The preferred implementation methods and materials described herein are for demonstration purposes only and are not intended to limit the content of this application.

[0026] The experimental methods in the following examples are conventional methods unless otherwise specified; the experimental materials and test strains used in the following examples are purchased from commercial channels unless otherwise specified.

[0027] Example 1

[0028] A medicinal and edible formula for resisting colds and enhancing immunity

[0029] The medicine and food formula includes the following components in parts by weight: 20 grams of astragalus or its extract; 50 grams of ginseng or its extract; 10 grams of perilla leaf or its extract; 50 grams of purslane or its extract; 20 grams of honeysuckle or its extract; 40 grams of kudzu root or its extract; 10 grams of salvia miltiorrhiza or its extract; 40 grams of epimedium or its extract; 30 grams of ophiopogon or its extract; 30 grams of licorice or its extract; 20 grams of schisandra chinensis or its extract; 40 grams of polygonatum or its extract; 30 grams of rehmannia root or its extract; 40 grams of atractylodes or its extract.

[0030] The present invention also provides a method for preparing a medicine-food formula for resisting colds and enhancing immunity, the preparation method comprising the following steps:

[0031] (1) taking the above-mentioned Chinese medicinal raw materials by weight, washing them and drying them;

[0032] (2) placing the mixed raw materials in a container and adding water to soak them;

[0033] (3) First, boil the water over high heat, then simmer over low heat for 30-60 minutes, filter, and obtain the first decoction;

[0034] (4) adding 3-5 times the amount of water to the filter residue, decocting for a second time according to the above decoction method, filtering, and obtaining a second decoction liquid;

[0035] (5) combining the two decoctions and concentrating them into an extract with a relative density of 1.05-1.15;

[0036] (6) Drying and crushing the extract to prepare a powder.

[0037] Wherein, the weight of water in step (2) is 5-10 times the total weight of the raw materials.

[0038] Wherein, the soaking time in step (2) is 1-2 hours.

[0039] Wherein, the temperature condition of relative density in step (5) is 60-70°C.

[0040] In the step (6), suitable auxiliary materials such as starch, dextrin, etc. may be added to prepare oral dosage forms such as granules, tablets or capsules.

[0041] Example 2

[0042] A medicinal and edible formula for resisting colds and enhancing immunity

[0043] The medicine and food formula includes the following components in parts by weight: 30 grams of astragalus or its extract; 40 grams of ginseng or its extract; 30 grams of perilla leaf or its extract; 40 grams of purslane or its extract; 30 grams of honeysuckle or its extract; 30 grams of kudzu root or its extract; 20 grams of salvia miltiorrhiza or its extract; 30 grams of epimedium or its extract; 40 grams of ophiopogon or its extract; 20 grams of licorice or its extract; 40 grams of schisandra chinensis or its extract; 30 grams of polygonatum or its extract; 35 grams of rehmannia root or its extract; 30 grams of atractylodes or its extract.

[0044] The present invention also provides a method for preparing a medicine-food formula for resisting colds and enhancing immunity, and the preparation method is carried out with reference to Example 1.

[0045] Example 3

[0046] A medicinal and edible formula for resisting colds and enhancing immunity

[0047] The medicine and food formula includes the following components in parts by weight: 40 grams of astragalus or its extract; 30 grams of ginseng or its extract; 50 grams of perilla leaf or its extract; 30 grams of purslane or its extract; 40 grams of honeysuckle or its extract; 20 grams of kudzu root or its extract; 30 grams of salvia miltiorrhiza or its extract; 20 grams of epimedium or its extract; 50 grams of ophiopogon or its extract; 10 grams of licorice or its extract; 20 grams of schisandra chinensis or its extract; 60 grams of polygonatum or its extract; 30 grams of rehmannia root or its extract; 40 grams of atractylodes or its extract.

[0048] The present invention also provides a method for preparing a medicine-food formula for resisting colds and enhancing immunity, and the preparation method is carried out with reference to Example 1.

[0049] Experimental Example 1

[0050] Thirty healthy SPF-grade BALB / c mice were selected and randomly divided into three groups, each with 10 mice, namely, Example 1 group, Example 2 group and Example 3 group. The mice in each group were intraperitoneally injected with cyclophosphamide to establish an immunosuppression model, and were given oral administration at a dose equivalent to 10 g of the crude drug per kilogram of body weight, once a day, for 14 consecutive days; after the experiment, the mice were killed, the spleen and thymus were removed, weighed, and the immune organ index was calculated.

[0051] Result analysis: Figure 1 As shown, the immune organ indexes of the mice in Example 1-3 groups were all at a high level, among which the immune organ index of the mice in Example 2 group was the highest, followed by Example 1 group and Example 3 group.

[0052] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

[0053] The present invention and its embodiments are described above, and such description is not restrictive. The drawings show only one embodiment of the present invention, and the actual structure is not limited thereto. In short, if ordinary technicians in the field are inspired by it, without departing from the purpose of the invention, they can design a structure and embodiment similar to the technical solution without creativity, which should belong to the protection scope of the present invention.

Claims

1. A medicinal and edible formula for resisting colds and enhancing immunity, characterized in that: The medicine and food formula includes the following components in parts by weight: 5 to 90 grams of astragalus or its extract; 5 to 90 grams of ginseng or its extract; 5 to 90 grams of perilla leaf or its extract; 10 to 90 grams of purslane or its extract; 5 to 60 grams of honeysuckle or its extract; 5 to 60 grams of kudzu root or its extract; 5 to 60 grams of salvia miltiorrhiza or its extract; 5 to 60 grams of epimedium or its extract; 5 to 60 grams of ophiopogon or its extract; 5 to 60 grams of liquorice or its extract; 5 to 60 grams of schisandra chinensis or its extract; 5 to 60 grams of polygonatum or its extract; 5 to 60 grams of rehmannia root or its extract; 5 to 60 grams of atractylodes macrocephala or its extract.

2. The food-medicine formula for preventing colds and enhancing immunity according to claim 1, characterized in that: The medicine and food formula includes the following components in parts by weight: 10 to 70 grams of astragalus or its extract; 20 to 80 grams of ginseng or its extract; 5 to 70 grams of perilla leaf or its extract; 20 to 80 grams of purslane or its extract; 15 to 60 grams of honeysuckle or its extract; 10 to 50 grams of kudzu root or its extract; 10 to 60 grams of salvia miltiorrhiza or its extract; 10 to 60 grams of epimedium or its extract; 20 to 50 grams of ophiopogon or its extract; 10 to 50 grams of liquorice or its extract; 15 to 60 grams of schisandra or its extract; 10 to 50 grams of polygonatum or its extract; 20 to 50 grams of rehmannia root or its extract; 10 to 60 grams of atractylodes or its extract.

3. The food-medicine formula for preventing colds and enhancing immunity according to claim 2, characterized in that: The medicine and food formula includes the following components in parts by weight: 20-40 grams of astragalus or its extract; 30-50 grams of ginseng or its extract; 10-50 grams of perilla leaf or its extract; 30-50 grams of purslane or its extract; 20-40 grams of honeysuckle or its extract; 20-40 grams of kudzu root or its extract; 10-30 grams of salvia miltiorrhiza or its extract; 20-40 grams of epimedium or its extract; 30-50 grams of ophiopogon or its extract; 10-30 grams of liquorice or its extract; 20-60 grams of schisandra chinensis or its extract; 20-40 grams of polygonatum or its extract; 30-40 grams of rehmannia root or its extract; 20-40 grams of atractylodes macrocephala or its extract.

4. A method for preparing the medicine-food formula for resisting colds and enhancing immunity according to claim 3, characterized in that: The preparation method comprises the following steps: (1) taking the above-mentioned Chinese medicinal raw materials by weight, washing them and drying them; (2) placing the mixed raw materials in a container and adding water to soak them; (3) First, boil the water over high heat, then simmer over low heat for 30-60 minutes, filter, and obtain the first decoction; (4) adding 3-5 times the amount of water to the filter residue, decocting for a second time according to the above decoction method, filtering, and obtaining a second decoction liquid; (5) combining the two decoctions and concentrating them into an extract with a relative density of 1.05-1.15; (6) Drying and crushing the extract to prepare a powder.

5. The method for preparing a food-medicine combination for resisting colds and enhancing immunity according to claim 4, characterized in that: The weight of water in step (2) is 5-10 times the total weight of the raw materials.

6. The method for preparing a medicinal and edible formula for resisting colds and enhancing immunity according to claim 5, characterized in that: The soaking time in step (2) is 1-2 hours.

7. The method for preparing a medicinal and edible formula for resisting colds and enhancing immunity according to claim 6, characterized in that: The temperature condition of relative density in step (5) is 60-70°C.

8. The method for preparing a medicinal and edible formula for resisting colds and enhancing immunity according to claim 7, characterized in that: Appropriate auxiliary materials, such as starch, dextrin, etc., may also be added in step (6) to prepare oral dosage forms such as granules, tablets or capsules.

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