Tooth film and preparation method thereof

Abstract

The invention provides a tooth film. The tooth film comprises a stripping layer, a whitening layer and a backing layer, the stripping layer and the backing layer are polyolefin films; the whitening layer is prepared from the following components in parts by weight: 10 to 20 parts of a modified whitening agent, 15 to 35 parts of a thickening agent, 5 to 10 parts of a humectant, 0.3 to 0.8 part of a stabilizer, 0.1 to 0.5 part of a bacteriostatic agent, 1 to 3 parts of a modified anti-allergic agent and 0.5 to 1.5 parts of a pH regulator. The tooth film prepared by the invention has a good whitening effect, and is non-irritant and good in stability.

Description

Technical Field

[0001] The invention belongs to the technical field of tooth whitening product preparation, and specifically relates to a tooth film and a preparation method thereof. Background Art

[0002] As people pay more and more attention to teeth whitening care, many related products have been produced accordingly, such as whitening care toothpaste, dental bleaching solution, mouthwash, teeth whitening gel, teeth whitening film, etc. Among them, the tooth whitening film is relatively simple, convenient and beautiful to use, and is recognized by more and more consumers.

[0003] Among the current products, the main methods for teeth whitening are ultrasonic cleaning or chemical bleaching. For the former, it only cleans the teeth, but cannot discolor and whiten tooth stains. In addition, the mechanical operation will thin the tooth enamel and damage the tooth substance. It requires professional personnel to operate and is inconvenient. For the latter, it is mainly administered through braces, which are worn for a long time, so that high-concentration peroxide bleaching agents such as hydrogen peroxide are in contact with the pressing surface for a long time, and then the teeth are whitened through the released effective ingredients. However, because high-concentration peroxides are highly acidic, they are more irritating to the teeth, and the treatment time is long and the price is expensive.

[0004] Currently, there are two types of teeth whitening films: dry films and wet films. Most of these films use peroxide as the main bleaching agent, and peroxide is irritating and has a strong irritating effect on teeth and surrounding tissues. Therefore, it is particularly necessary to develop a teeth film with less irritation and good whitening effect. Summary of the invention

[0005] The purpose of the present invention is to provide a tooth film and a preparation method thereof, wherein a peeling layer, a whitening layer and a backing layer are arranged, a modified whitening agent is obtained by loading superoxide dismutase, sodium hypochlorite and chitinase on diatomaceous earth, a modified stabilizer is obtained by modifying aluminum magnesium silicate and chitin with carbon fiber, and under the action of a thickener, a moisturizer, an antibacterial agent and the like, the obtained tooth film has a good whitening effect, is non-irritating and has good stability.

[0006] In order to achieve the above object, the present invention provides the following technical solutions: A tooth film comprises a peeling layer, a whitening layer and a backing layer; the peeling layer and the backing layer are both polyolefin films; the whitening layer is prepared from the following components in parts by weight: 10-20 parts of a modified whitening agent, 15-35 parts of a thickener, 5-10 parts of a moisturizer, 0.3-0.8 parts of a stabilizer, 0.1-0.5 parts of an antibacterial agent, 1-3 parts of a modified anti-sensitizer, and 0.5-1.5 parts of a pH regulator.

[0007] Preferably, the thickness of the peeling layer is 0.05-0.5 mm, the thickness of the whitening layer is 0.05-1.5 mm, and the thickness of the backing layer is 0.005-0.02 mm.

[0008] Preferably, the modified whitening agent is diatomaceous earth loaded with superoxide dismutase, sodium hypochlorite and chitinase; the thickener is prepared from carrageenan and ethyl cellulose; the moisturizer is prepared from propylene glycol, triethanolamine and menthol; the stabilizer is carbon fiber modified magnesium aluminum silicate and chitosan; the antibacterial agent is nano zinc oxide; the modified anti-allergic agent is a plant-extracted anti-allergic agent; the pH adjuster is malic acid or citric acid.

[0009] A method for preparing a tooth film comprises the following steps: S1: In parts by weight, 10-20 parts of modified whitening agent, 15-35 parts of thickener, 5-10 parts of moisturizer, 0.3-0.8 parts of stabilizer, 0.1-0.5 parts of antibacterial agent, 1-3 parts of modified anti-allergic agent, and 0.5-1.5 parts of pH adjuster are added into a vacuum tank according to the proportions, mixed and stirred to obtain a teeth whitening gel; S2: Prepare a release layer and a backing layer from a polyolefin film, respectively, and control the thickness of the release layer to be 0.05-0.5 mm, and the thickness of the backing layer to be 0.005-0.02 mm; apply the teeth whitening gel described in step S1 on the release layer made of the polyolefin film to obtain a whitening layer, and control the thickness of the whitening layer to be 0.05-1.5 mm; put the whole into a dryer for drying, and obtain a whitening tooth paste after cutting.

[0010] Preferably, the preparation process of the modified whitening agent in step S1 is: by weight, 7-12 parts of superoxide dismutase and 5-10 parts of chitinase are mixed for 5-10 minutes; then 4-8 parts of a 25% by weight sodium hypochlorite aqueous solution are added thereto, and the mixture is stirred for 10-15 minutes; then 1-3 parts of diatomaceous earth are added, and the mixture is stirred and reacted at a temperature of 40-50° C. for 25-45 minutes to obtain the modified whitening agent.

[0011] Preferably, the stabilizer in step S1 is calculated by weight, and 5-10 parts of carbon fiber, 3-7 parts of aluminum magnesium silicate and 2-5 parts of chitosan are mixed, and stirred at a temperature of 60-80° C. for 30-50 minutes to obtain a modified stabilizer.

[0012] Preferably, the thickener in step S1 is prepared by mixing 10-20 parts of carrageenan and 3-5 parts of ethyl cellulose by weight.

[0013] Preferably, the preparation process of the modified anti-allergic agent in step S1 is: by weight, 3-8 parts of Scutellaria baicalensis, 2-6 parts of Glycyrrhiza glabra, and 3-5 parts of Chamomile flowers are mixed, and the mixture is dried, crushed, and subjected to supercritical flow extraction to obtain the modified anti-allergic agent.

[0014] Preferably, the supercritical flow extraction in step S1 has a pressure of 30-50 MPa, a temperature of 35-45° C., a time of 80-100 min, an entrainer of ethyl acetate, and an addition amount of the entrainer of 2-6 wt %.

[0015] Preferably, the moisturizing agent is a mixture of 8-12 parts of propylene glycol, 4-7 parts of triethanolamine and 7-10 parts of menthol.

[0016] Compared with the prior art, the advantages and beneficial effects of the present invention are: The invention uses diatomaceous earth to modify superoxide dismutase, chitinase and sodium hypochlorite aqueous solution to prepare the modified whitening agent, and only a very small amount of peroxide is used to obtain a good whitening effect, and the whitening is mild and less irritating; under the synergistic effect of a stabilizer mixed with carbon fiber, aluminum magnesium silicate and chitosan, the stability is high; after supercritical flow extraction of scutellaria baicalensis, glycyrrhiza glabra and chamomile, the modified anti-sensitizer is obtained, so that the tooth paste maintains good anti-sensitivity and anti-inflammatory effects; the prepared tooth paste composed of a three-layer structure of a peeling layer, a whitening layer and a backing layer is equivalent to a traditional peroxide whitening paste, is safe and reliable, has no side effects, and has a better whitening effect. DETAILED DESCRIPTION

[0017] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0018] The sources of raw materials used in the present invention are as follows: Superoxide dismutase was from Shanghai Yuanye Biotechnology Co., Ltd., item number S10116; chitinase was from Shanghai Yuanye Biotechnology Co., Ltd., item number S10178; diatomaceous earth was from Shandong Zhengxing New Materials Co., Ltd., item number CG8; carbon fiber was from Xi'an Limei Building Materials Co., Ltd., item number 1955; chitin was from Shanghai Yuanye Biotechnology Co., Ltd., item number S11065; carrageenan was from Shanghai Yuanye Biotechnology Co., Ltd., item number S30559; ethyl cellulose was from Shanghai Yuanye Biotechnology Co., Ltd., item number S14026; scutellaria baicalensis was from Shanghai Yuanye Biotechnology Co., Ltd., item number B20571; glycyrrhiza uralensis was from Shanghai Yuanye Biotechnology Co., Ltd., item number B28337; chamomile was from Shenzhen Excellence Biotechnology Co., Ltd., item number 4692; menthol was from Shanghai Yuanye Biotechnology Co., Ltd., item number S30540; polyolefin film was from Haozheng New Materials Technology (Dongguan) Co., Ltd., item number QF570-3.

[0019] Example 1 This embodiment provides a method for preparing a tooth film, comprising the following steps: S1: Take 7g superoxide dismutase and 5g chitinase and stir them at a rate of 350r / min for 5min; then add 4g sodium hypochlorite aqueous solution with a mass fraction of 25%, stir and mix at a rate of 400r / min for 10min at a temperature of 60℃; then add 1g diatomaceous earth, stir and react at a rate of 350r / min at a temperature of 40℃ for 25min to obtain a modified whitening agent; take 5g carbon fiber, 3g aluminum magnesium silicate and 2g chitin and mix them, stir and react at a temperature of 60℃ at a rate of 450r / min. 30 minutes to obtain a modified stabilizer; 10g carrageenan and 3g ethyl cellulose were stirred and mixed at a speed of 450r / min to obtain a 10min thickener; 3g scutellaria baicalensis, 2g licorice, and 3g chamomile were mixed, dried at 80°C, crushed, and subjected to supercritical flow extraction at a pressure of 30MPa, a temperature of 35°C, a time of 80min, and an entrainer of 2wt% ethyl acetate to obtain a modified anti-allergic agent; 8g propylene glycol, 4g triethanolamine, and 7g menthol were stirred and mixed at a speed of 250r / min for 10min to obtain a moisturizer; 10 g of modified whitening agent, 15 g of thickener, 5 g of moisturizer, 0.3 g of stabilizer, 0.1 g of antibacterial agent nano zinc oxide, 1 g of modified anti-allergic agent, and 0.5 g of pH regulator malic acid were added into a vacuum tank, the vacuum degree was 0.03 Pa, and the mixture was mixed and stirred at a rate of 400 r / min for 34 min to obtain a teeth whitening gel; S2: Prepare a release layer and a backing layer from a polyolefin film, respectively, and control the thickness of the release layer to be 0.05 mm and the thickness of the backing layer to be 0.005 mm; apply the teeth whitening gel described in step S1 on the release layer made of the polyolefin film to obtain a whitening layer, and control the thickness of the whitening layer to be 0.05 mm; put the whole into a dryer for drying, and obtain a whitening tooth paste after cutting.

[0020] Example 2 This embodiment provides a method for preparing a tooth film, comprising the following steps: S1: Take 12g superoxide dismutase and 10g chitinase and stir them at a rate of 250r / min for 10min; then add 8g sodium hypochlorite aqueous solution with a mass fraction of 25% and stir them at a rate of 300r / min for 15min; then add 3g diatomaceous earth and stir them at a temperature of 50℃ and a rate of 400r / min for 45min to obtain a modified whitening agent; take 10g carbon fiber, 7g aluminum magnesium silicate and 5g chitin and mix them, stir them at a temperature of 80℃ and a rate of 350r / min for 50min. min, to obtain a modified stabilizer; 20g carrageenan and 5g ethyl cellulose were stirred and mixed at a rate of 300r / min for 15min to obtain a thickener; 8g scutellaria baicalensis, 6g licorice, and 5g chamomile were mixed, dried at 80°C, crushed, and subjected to supercritical flow extraction at a pressure of 50MPa, a temperature of 45°C, a time of 100min, and an entrainer of 6wt% ethyl acetate to obtain a modified anti-allergic agent; 12g propylene glycol, 7g triethanolamine, and 10g menthol were stirred and mixed at room temperature at a rate of 300r / min for 10min to obtain a moisturizer; 20 g of modified whitening agent, 35 g of thickener, 10 g of moisturizer, 0.8 g of stabilizer, 0.5 g of antibacterial agent nano zinc oxide, 3 g of modified anti-allergic agent, and 1.5 g of pH regulator malic acid were added into a vacuum tank, the vacuum degree was 0.06 Pa, and the mixture was stirred at a rate of 500 r / min for 55 min to obtain a teeth whitening gel; S2: Prepare a release layer and a backing layer from a polyolefin film, respectively, with the thickness of the release layer controlled to be 0.5 mm and the thickness of the backing layer controlled to be 0.02 mm; apply the teeth whitening gel described in step S1 on the release layer made of the polyolefin film to obtain a whitening layer, with the thickness of the whitening layer controlled to be 1.5 mm; put the whole into a dryer for drying, and obtain a whitening tooth paste after cutting.

[0021] Example 3 This embodiment provides a method for preparing a tooth film, comprising the following steps: S1: Take 10g superoxide dismutase and 8g chitinase and stir them at a rate of 300r / min for 7min; then add 6g sodium hypochlorite aqueous solution with a mass fraction of 25% and stir them at a rate of 400r / min for 12min; then add 2g diatomaceous earth and stir them at 350r / min for 35min at a temperature of 45℃ to obtain a modified whitening agent; take 7g carbon fiber, 5g aluminum magnesium silicate and 3g chitin and mix them, stir them at 350r / min for 45min at a temperature of 75℃ , a modified stabilizer was obtained; 16g carrageenan and 4g ethyl cellulose were stirred and mixed at a rate of 600r / min for 10min to obtain a thickener; 5g scutellaria baicalensis, 5g licorice, and 4g chamomile were mixed, dried at 80°C, crushed, and subjected to supercritical flow extraction at a pressure of 45MPa, a temperature of 40°C, a time of 90min, and 4wt% ethyl acetate as an entrainer to obtain a modified anti-allergic agent; 10g propylene glycol, 6g triethanolamine, and 8g menthol were stirred and mixed at room temperature at a rate of 400r / min for 10min to obtain a moisturizer; 10-20 g of modified whitening agent, 15-35 g of thickener, 5-10 g of moisturizer, 0.3-0.8 g of stabilizer, 0.1-0.5 g of antibacterial agent nano zinc oxide, 1-3 g of modified anti-allergic agent, and 0.5-1.5 g of pH regulator malic acid are added into a vacuum tank, the vacuum degree is 0.045 Pa, and the mixture is stirred at a rate of 500 r / min for 45 min to obtain a tooth whitening gel; S2: Prepare a release layer and a backing layer from a polyolefin film, respectively, with the thickness of the release layer controlled to be 0.25 mm and the thickness of the backing layer controlled to be 0.008 mm; apply the teeth whitening gel described in step S1 on the release layer made of the polyolefin film to obtain a whitening layer, with the thickness of the whitening layer controlled to be 0.95 mm; put the whole into a dryer for drying, and obtain a whitening tooth paste after cutting.

[0022] Comparative Example 1 The difference between this comparative example and Example 1 is that superoxide dismutase and chitinase are not added in step S1, and the other steps are the same.

[0023] Comparative Example 2 The difference between this comparative example and Example 1 is that diatomaceous earth is not added in step S1, and the other steps are the same.

[0024] Comparative Example 3 The difference between this comparative example and Example 1 is that sodium metasilicate is not added in step S1, and the other steps are the same.

[0025] Comparative Example 4 The difference between this comparative example and Example 1 is that chitosan is not added in step S1, and the other steps are the same.

[0026] Comparative Example 5 The difference between this comparative example and Example 1 is that no modified antisensitizer is added in step S1, and the other steps are the same.

[0027] Comparative Example 6 The difference between this comparative example and Example 1 is that in step S1, supercritical flow extraction is not used, but extraction is performed in an ethanol solution, and the other steps are the same.

[0028] Performance Test: Adhesion effect: The whitening tooth stickers made according to the embodiment and the comparative example are used by 3-5 people. The method of use is as follows: tear off the tooth sticker, stick it on the teeth for 15-20 minutes, then tear it off from the teeth, and observe whether there is gel retention on the teeth. If there is, it means that it is adhered to the teeth, and if not, it means that it is not adhered to the teeth.

[0029] Whitening effect: Use cow teeth as the test object, compare with the color card first, and get the initial chromaticity value; apply the gel layer of the whitening tooth paste on the cow teeth, place it in an environment of 25-30℃ for 30 minutes, then rinse and dry, and compare with the color card to get the chromaticity value after whitening. Initial chromaticity value - chromaticity value after whitening = whitening effect value.

[0030] Stability: After standing for 24 hours, the samples of each embodiment and comparative example were respectively placed in 100 ml transparent plastic bottles and stood for 3 months at 4°C, room temperature (20-25°C) and 45°C to observe the stability.

[0031] The results are shown in Table 1 below.

[0032] Table 1 Performance test results

[0033] From the above performance test results, it can be seen that Examples 1-3 have good whitening effect and anti-stickiness; in particular, the comprehensive performance of Example 3 is the most outstanding. However, since Comparative Examples 1-6 do not adopt the necessary technical solutions, their corresponding performance tests are significantly worse than those of the Examples. The above experimental results further prove the importance of the technical solutions defined in the present invention for its technical effects.

[0034] The above is a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A tooth film, characterized in that: It comprises a peeling layer, a whitening layer and a backing layer; the peeling layer and the backing layer are both polyolefin films; the whitening layer is prepared from the following components in parts by weight: 10-20 parts of a modified whitening agent, 15-35 parts of a thickener, 5-10 parts of a moisturizer, 0.3-0.8 parts of a stabilizer, 0.1-0.5 parts of an antibacterial agent, 1-3 parts of a modified anti-allergic agent, and 0.5-1.5 parts of a pH regulator.

2. A tooth film according to claim 1, characterized in that: The thickness of the peeling layer is 0.05-0.5 mm, the thickness of the whitening layer is 0.05-1.5 mm, and the thickness of the backing layer is 0.005-0.02 mm.

3. A tooth film according to claim 1, characterized in that: The modified whitening agent is made of diatomaceous earth loaded with superoxide dismutase, sodium hypochlorite and chitinase; the thickener is made of carrageenan and ethyl cellulose; the moisturizer is made of propylene glycol, triethanolamine and menthol; the stabilizer is made of carbon fiber modified aluminum magnesium silicate and chitin; the antibacterial agent is nano zinc oxide; the modified anti-allergic agent is a plant-extracted anti-allergic agent; and the pH regulator is malic acid or citric acid.

4. A method for preparing a tooth film, characterized in that: The following steps are included: S1: In parts by weight, 10-20 parts of modified whitening agent, 15-35 parts of thickener, 5-10 parts of moisturizer, 0.3-0.8 parts of stabilizer, 0.1-0.5 parts of antibacterial agent, 1-3 parts of modified anti-allergic agent, and 0.5-1.5 parts of pH adjuster are added into a vacuum tank according to the proportions, mixed and stirred to obtain a teeth whitening gel; S2: Prepare a release layer and a backing layer from a polyolefin film, respectively, and control the thickness of the release layer to be 0.05-0.5 mm, and the thickness of the backing layer to be 0.005-0.02 mm; apply the teeth whitening gel described in step S1 on the release layer made of the polyolefin film to obtain a whitening layer, and control the thickness of the whitening layer to be 0.05-1.5 mm; put the whole into a dryer for drying, and obtain a whitening tooth paste after cutting.

5. The method for preparing a tooth film according to claim 4, characterized in that: The preparation process of the modified whitening agent in step S1 is as follows: by weight, 7-12 parts of superoxide dismutase and 5-10 parts of chitinase are mixed for 5-10 minutes; then 4-8 parts of a 25% by weight sodium hypochlorite aqueous solution are added thereto, and the mixture is stirred for 10-15 minutes; then 1-3 parts of diatomaceous earth are added, and the mixture is stirred and reacted at a temperature of 40-50° C. for 25-45 minutes to obtain the modified whitening agent.

6. The method for preparing a tooth film according to claim 4, characterized in that: The stabilizer in step S1 is calculated by weight, and 5-10 parts of carbon fiber, 3-7 parts of magnesium aluminum silicate and 2-5 parts of chitosan are mixed, and stirred at a temperature of 60-80° C. for 30-50 minutes to obtain a modified stabilizer.

7. The method for preparing a tooth film according to claim 4, characterized in that: The thickener in step S1 is calculated by weight by mixing 10-20 parts of carrageenan and 3-5 parts of ethyl cellulose.

8. The method for preparing a tooth film according to claim 4, characterized in that: The preparation process of the modified anti-allergic agent in step S1 is as follows: by weight, 3-8 parts of Scutellaria baicalensis, 2-6 parts of Glycyrrhiza glabra, and 3-5 parts of Chamomile flowers are mixed, and the mixture is dried, crushed, and subjected to supercritical flow extraction to obtain the modified anti-allergic agent.

9. The method for preparing a tooth film according to claim 8, characterized in that: The supercritical flow extraction in step S1 has a pressure of 30-50 MPa, a temperature of 35-45° C., a time of 80-100 min, and an entrainer of ethyl acetate, and an addition amount of the entrainer of 2-6 wt %.

10. The method for preparing a tooth film according to claim 4, characterized in that: The moisturizing agent is a mixture of 8-12 parts of propylene glycol, 4-7 parts of triethanolamine and 7-10 parts of menthol.

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