Parasite-expelling traditional Chinese medicine extract trace element vitamin sustained-release pill for ruminants

By developing trace element vitamin sustained-release pills for deworming Chinese medicine extract for ruminants, the drug resistance and drug residues of traditional deworming drugs have been solved, and long-acting deworming and trace element vitamin supplementation has been achieved, and it is convenient and safe to use. Environmental friendly.

CN119454625AInactive Publication Date: 2025-02-18SHANDONG LUXI ANIMAL MEDICINE SHARE CO LTD
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Patent Information

Application Number
CN202411523490.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-10-29
Publication Date
2025-02-18
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

In the prior art, traditional antiworming drugs have drug resistance problems and require frequent feeding, which consumes a lot of manpower and material resources. At the same time, it may lead to drug residues in livestock products, endangering human health.

Method used

A sustained-release pill of trace element vitamin in ruminants was developed. By combining anti-worm Chinese herbal extract, trace element and vitamin with molding substances such as silicate cement, it forms sustained-release pills, using iron powder and The counterweight effect of silicate cement and the epoxy resin to prevent digestion and corrosion of the shell, achieving the slow release of traditional Chinese medicine extracts.

Benefits of technology

Sustained-release pills that feed 1-2 capsules at a time can be effectively dewormed within 6-9 months, meeting the needs of trace elements and vitamins, avoiding drug resistance problems and drug residues, and are easy to use, safe and environmentally friendly.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses insect-expelling traditional Chinese medicine extract trace element vitamin sustained-release pills for ruminants, and belongs to the technical field of cultivation, the insect-expelling traditional Chinese medicine extract trace element vitamin sustained-release pills comprise insect-expelling pills for releasing insect-expelling traditional Chinese medicines, counterweight pills, a digestion corrosion resistant shell for preventing the sustained-release pills from being quickly dissolved and released, and the insect-expelling pills are embedded in the inner wall of the digestion corrosion resistant shell. The counter weight pill is embedded in the inner wall of one end of the digestion corrosion resisting shell, and the parasite expelling pill comprises the following raw materials: parasite expelling traditional Chinese medicine extract, trace elements, vitamins and extrusion forming materials. The parasite-expelling traditional Chinese medicine extract is prepared by mixing one or more of szechwan chinaberry fruit, azedarach, Chinese torreya, smoked plum, quispualis indica, radix stemonae, betel nut, stone-like omphalia, rhizoma dryopteris crassirhizomae, wild carrot fruit, radix euphorbiae lantu and pumpkin seed according to any proportion. The purpose of expelling parasites for cattle and sheep for 6-9 months can be achieved by feeding the cattle and sheep with sustained-release pills, meanwhile, the requirements of microelements and vitamins are met, the problem of drug resistance is avoided, drug residues are avoided, and the method is labor-saving, safe and environment-friendly.
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Description

Technical Field

[0001] The invention relates to the technical field of breeding, and more particularly to a sustained-release pill of anthelmintic Chinese medicine extracts and trace elements and vitamins for ruminants. Background Art

[0002] If my country's cattle and sheep farming industry is to achieve healthy and sustainable development, the only way to achieve better economic benefits is to reduce breeding costs, change breeding methods, and adopt more low-input natural grazing models or low-input (feeding less or no concentrate supplements) confinement models.

[0003] Deworming is very important to keep cattle and sheep healthy. The traditional deworming method is to do it regularly, usually once every 1-2 months, by gathering cattle and sheep together and injecting or feeding them with deworming drugs. This method requires a lot of manpower and material resources and is not economical.

[0004] Traditional antiparasitic drugs mainly include: 1. Benzimidazoles: albendazole, fenbendazole; 2. Avermectins: ivermectin, avermectin; 3. Others: praziquantel, iodoxamide sodium. These drugs have been used for decades, have serious drug resistance, and are prone to cause drug residues in livestock products, endangering human health.

[0005] In order to solve the above problems, we invented a kind of anthelmintic Chinese medicine extract trace element vitamin sustained-release pill for ruminants. Feeding 1-2 pills at a time can achieve the purpose of anthelmintic for cattle and sheep for 6-9 months, and meet the needs of trace elements and vitamins at the same time. There is no drug resistance problem, no drug residue, and it saves labor and energy, is safe and environmentally friendly, and is beneficial to human health. Summary of the invention

[0006] 1. Technical problems to be solved

[0007] In view of the problems existing in the prior art, the present invention provides a ruminant Chinese medicine extract trace element vitamin sustained-release pill, which includes ruminant Chinese medicine extract, trace elements, vitamin A, vitamin D3 and vitamin E required by ruminants, and is extruded using silicate cement as a molding material. The weighted pills extruded with iron powder and silicate cement are used to prevent the pills from being discharged (the iron powder is destroyed under the acidic effect in the rumen and eventually discharged from the body with the gastrointestinal contents). Except for the S2 end, the outside of the pills is coated with epoxy resin, which ensures that the pills can only slowly dissolve and release the Chinese medicine extract, trace elements and vitamins from the head end.

[0008] The anthelmintic extracts used are: extracts of Chuanlianzi, Melia azedarach bark, Torreya grandis, Prunus mume, Quisqualis chinensis, Stemona tuberosa, Areca catechu, Thunder ball, Cynomorium strychnifolium, South Heshi, Wolfberry and Pumpkin Seed. For example, Chuanlianzi has the functions of soothing the liver and relieving depression, relieving pain and expelling worms. It is mainly used to treat abdominal distension caused by qi stagnation, pain in the waist and hips, and worm accumulation. The active ingredient in the extract is Toosendanin (C 30 H 38 O 11 ), a cow only needs 0.03-0.05g at a time to have a very good deworming effect. Another example is the above-mentioned Quisqualis chinensis, which has the function of killing insects and eliminating accumulation, and is mainly used to treat abdominal pain caused by insect accumulation, ascariasis, and pinworm disease. The active ingredient in the extract is trigonelline (C7H7NO2), and a cow only needs 0.1-0.2g of deworming dose at a time. Using one or more of the above drug extracts in combination according to the 9-month dosage to add to the sustained-release pills, it can achieve the purpose of long-term deworming or prevention of tapeworms, pinworms, hookworms and ascaris while supplementing trace elements and vitamins with a single dose.

[0009] 2. Technical solution

[0010] To solve the above problems, the present invention adopts the following technical solutions:

[0011] A ruminant Chinese medicine extract trace element vitamin sustained-release pill comprising:

[0012] Anti-worm pills are used to release anti-worm Chinese medicine.

[0013] Weight pills, used for counterweight.

[0014] The digestion-resistant shell is used to prevent the sustained-release pellets from being rapidly dissolved and released.

[0015] A plurality of the anthelmintic pills are embedded in the inner wall of the anti-digestion and corrosion shell, and the weighted pills are embedded in the inner wall of one end of the anti-digestion and corrosion shell.

[0016] The anthelmintic pills include the following raw materials: anthelmintic Chinese medicine extracts, trace elements, vitamins, and extrusion molding materials.

[0017] The anthelmintic Chinese medicine extract is prepared by mixing one or more of Toosendan fruit, Melia azedarach bark, Torreya grandis, Prunus mume, Quisqualis chinensis, Stemona tuber, Areca catechu, Lepidium melongena, Cynomorium strychnos, Ligusticum chuanxiong, Wolfberry chamaejasme and Cucurbita cuspidata in any proportion, and the proportion of the anthelmintic Chinese medicine extract in the anthelmintic pill is 1%-10%.

[0018] The trace elements include 0.8%-1.2% sodium selenite, 15%-25% copper oxide, 0.3%-0.6% cobalt carbonate, 0.8%-1% calcium iodate, 20%-32% manganese sulfate, 7%-11% zinc sulfate and 10%-16% zinc oxide.

[0019] The vitamins include vitamin A 0.9%-1.3%, vitamin D 30.1%-0.3%, and vitamin E 1.0%-2.0%.

[0020] Furthermore, the extrusion molding material is prepared by mixing one or more of silicate cement, mine silicate cement, pozzolanic silicate cement, pulverized coal silicate cement and composite silicate cement in any proportion, and the extrusion molding material accounts for 9%-25%.

[0021] Furthermore, the weighted pills are made by mixing iron powder and silicate cement and then extruding them into pills, wherein the iron powder accounts for 75%-85% and the silicate cement accounts for 15%-25%.

[0022] Furthermore, the mixing ratio of the weighted pills to the anthelmintic pills is 15-25:100.

[0023] Furthermore, the anti-corrosion shell is epoxy resin.

[0024] Furthermore, the anthelmintic pill is cylindrical, 2-8 cm long and 1-3 cm in diameter.

[0025] Furthermore, the weight of the sustained-release pills is 30-120 g.

[0026] A method for preparing a vitamin sustained-release pill, which is applied to any one of the above-mentioned anthelmintic Chinese medicine extract trace element vitamin sustained-release pills for ruminants, comprises the following steps:

[0027] S1. Mix the weighed iron powder and silicate cement evenly, add water and continue mixing until uniform, then put the mixed materials into a pressing mold, press them into a cylindrical shape to obtain weighted pills, and the pressing pressure is 10-15 tons.

[0028] S2. Evenly mix the weighed Chinese herbal extract, trace elements, vitamins and cement, add appropriate amount of water and continue mixing until uniform, then put the mixed materials into a pressing mold, press into a cylindrical shape to obtain anthelmintic pills, and the pressing pressure is 10-15 tons.

[0029] S3, stacking the above pressed weighted pills and a plurality of anthelmintic pills, and filling them into the interior of the digestion and corrosion-resistant shell.

[0030] Furthermore, one end of the anti-oxidation and corrosion shell is sealed, the sealed end of the anti-oxidation and corrosion shell matches with the counterweight pill, and the other end of the anti-oxidation and corrosion shell is open.

[0031] A method for using a vitamin sustained-release pill, wherein the sustained-release pill is put into the rumen of a ruminant using a dosing device.

[0032] 3. Beneficial effects

[0033] Compared with the prior art, the advantages of the present invention are:

[0034] The anthelmintic extracts used are: extracts of Toosendan, Melia azedarach, Torreya grandis, Prunus mume, Quisqualis chinensis, Stemona tuberosa, Areca catechu, Thunder ball, Cynomorium strychnos, South Heshi, Wolfberry and Pumpkin Seed. For example, Toosendan has the functions of soothing liver and relieving depression, relieving pain and expelling worms. It is mainly used to treat abdominal distension caused by qi stagnation, waist and hip pain and worm accumulation. The active ingredient in the extract is Toosendanin (C 30 H 38 O 11 ), a cow only needs 0.03-0.05g at a time to have a very good anthelmintic effect. For example, the above-mentioned Quisqualis has the function of killing insects and eliminating accumulation. It is mainly used to treat abdominal pain caused by worm accumulation, ascariasis, and pinworm disease. The active ingredient in the extract is trigonelline (C7H7NO2). A cow only needs 0.1-0.2g of anthelmintic dose at a time. Use one or more of the above medicinal extracts in combination and add them to the sustained-release pills according to the dosage for 9 months. It can achieve the purpose of long-term anthelmintic or prevention of tapeworms, pinworms, hookworms and ascaris while supplementing trace elements and vitamins with a single dose. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] Figure 1 The present invention is a schematic structural diagram of a sustained-release pill of anthelmintic Chinese medicine extract trace elements and vitamins for ruminants.

[0036] Figure 2 The present invention is a schematic diagram of the preparation process of a worm-removing Chinese medicine extract trace element and vitamin sustained-release pill for ruminants.

[0037] In the picture: 1. Anthelmintic pills; 2. Weighted pills; 3. Anti-digestion and corrosion shell. DETAILED DESCRIPTION

[0038] The technical solutions in the embodiments of the present invention will be described clearly and completely below in combination with the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0039] Example 1, see Figure 1-2 :

[0040] Ratio of 1000g of weighted pellet 2:

[0041] Iron powder 800g

[0042] Cement 200g

[0043] Ratio of 1000g of anthelmintic pill 1:

[0044]

[0045] Production steps: S1. Evenly mix the weighed iron powder and silicate cement, add water to continue mixing until uniform, then put the mixed materials into a pressing mold, press into a cylindrical shape, and obtain a weighted pill 2, with a pressing pressure of 10-15 tons. S2. Evenly mix the weighed Chinese medicine extract, trace elements, vitamins and cement, add appropriate amount of water to continue mixing until uniform, then put the mixed materials into a pressing mold, press into a cylindrical shape, and obtain an anthelmintic pill 1, with a pressing pressure of 10-15 tons. S3. Stack the above pressed and formed weighted pills 2 with multiple anthelmintic pills 1, fill them into the interior of the anti-digestive corrosion shell 3, seal one end of the anti-digestive corrosion shell 3, the sealed end of the anti-digestive corrosion shell 3 matches the weighted pill 2, and the other end of the anti-digestive corrosion shell 3 is open, thus obtaining the present invention.

[0046] Example 2, see Figure 1-2 :

[0047] Ratio of 1000g of weighted pellet 2:

[0048] Iron powder 800g

[0049] Cement 200g

[0050] Ratio of 1000g of anthelmintic pill 1:

[0051]

[0052]

[0053] Production steps: S1. Mix the weighed iron powder and silicate cement evenly, add water to continue mixing until uniform, then put the mixed materials into a pressing mold, press into a cylindrical shape, and obtain a weighted pill 2, with a pressing pressure of 10-15 tons. S2. Mix the weighed Chinese medicine extract, trace elements, vitamins and cement evenly, add appropriate amount of water to continue mixing until uniform, then put the mixed materials into a pressing mold, press into a cylindrical shape, and obtain an anthelmintic pill 1, with a pressing pressure of 10-15 tons. S3. Stack the above pressed and formed weighted pills 2 with multiple anthelmintic pills 1, and fill them into the interior of the anti-digestive corrosion shell 3, seal one end of the anti-digestive corrosion shell 3, and the sealed end of the anti-digestive corrosion shell 3 matches the weighted pill 2, and the other end of the anti-digestive corrosion shell 3 is open, thereby obtaining the present invention.

[0054] Example 3, see Figure 1-2 :

[0055] Trial of sustained-release pellets to improve cattle production performance;

[0056] Experimental animals: 30 crossbred beef cattle, weighing 165-175 kg;

[0057] Test materials: the anthelmintic Chinese medicine extract trace element vitamin sustained-release pills for ruminants obtained in Example 1; 5% beef cattle trace element vitamin composite premix;

[0058] Test method: Randomly divide the test cattle into 3 groups, 10 cattle in each group, group A is the blank control group, the test cattle are fed with forage, group B is the sustained-release pill test group, each test cattle is given two sustained-release pills, and is fed with forage daily, group C is the premix test group, the test cattle are fed with forage and compound premix daily, and 5% fenbendazole powder is fed monthly for deworming, and each time the drug is used for 3 consecutive days, 0.15g per kilogram of body weight. All cattle are weighed on the first day of the test, and all cattle are weighed again at the end of the test to compare the weight gain of cattle between the groups. The test period is 9 months.

[0059] Test results:

[0060]

[0061] Note: a and b, different letters indicate significant difference between the two groups, and the same letters indicate no significant difference between the two groups.

[0062] The test results show that there is no difference in the weight gain effect of cattle when using the sustained-release pills of the present invention and 5% trace element vitamin compound premixes for cattle, indicating that the present invention can replace 5% trace element vitamin compound premixes and anthelmintic fenbendazole powder for cattle, and the present invention can be fed once, saving time and labor, and can greatly reduce breeding costs.

[0063] Example 4, see Figure 1-2 :

[0064] Trial on improving sheep production performance with sustained-release pellets;

[0065] Experimental animals: 30 3-month-old Boer goats, weighing 25-28 kg;

[0066] Test materials: the anthelmintic Chinese medicine extract trace element vitamin sustained-release pills for ruminants obtained in Example 2; 4% sheep trace element vitamin composite premix;

[0067] Test method: The test sheep were randomly divided into 3 groups, each with 10 sheep. Group A was a blank control group, where the test sheep were fed with forage. Group B was a sustained-release pill test group, where each test sheep was given 1 sustained-release pill and fed with forage daily. Group C was a premix test group, where the test sheep were fed with forage and compound premix daily, and 5% fenbendazole powder was fed monthly for deworming, and each time the drug was used for 3 consecutive days, 0.15g per kilogram of body weight. All the sheep were weighed on the first day of the test, and all the sheep were weighed again at the end of the test to compare the weight gain of the sheep between the groups. The test period was 6 months.

[0068] Test results:

[0069]

[0070] Note: a and b, different letters indicate significant difference between the two groups, and the same letters indicate no significant difference between the two groups.

[0071] It can be seen from the test results that there is no significant difference in the average weight gain of group B and group C in 6 months, indicating that the sheep can achieve the same effect as feeding 4% trace element vitamin composite premix and anthelmintic fenbendazole by using the present invention.

[0072] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and improved concepts of the present invention within the technical scope disclosed by the present invention, and they should be covered by the protection scope of the present invention.

Claims

1. A ruminant Chinese medicine extract trace element vitamin sustained-release pill, characterized in that: include: Anti-worm pills (1), for releasing anti-worm Chinese medicine; A weight pill (2), used for weighting; A digestion-resistant corrosion shell (3) is used to prevent the sustained-release pellets from being rapidly dissolved and released; A plurality of the anthelmintic pills (1) are embedded in the inner wall of the anti-digestive corrosion shell (3), and the weighted pills (2) are embedded in the inner wall of one end of the anti-digestive corrosion shell (3); The anthelmintic pill (1) comprises the following raw materials: anthelmintic Chinese medicine extract, trace elements, vitamins, and extrusion molding materials; The anthelmintic Chinese medicine extract is prepared by mixing one or more of Toosendan fruit, Melia azedarach bark, Torreya grandis, Prunus mume, Quisqualis chinensis, Stemona tuber, Areca catechu, Lepidium melongena, Cynomorium strychnos, Stellera chamaejasme and Cucurbita pekinensis in any proportion, and the proportion of the anthelmintic Chinese medicine extract in the anthelmintic pill (1) is 1%-10%; The trace elements include sodium selenite 0.8%-1.2%, copper oxide 15%-25%, cobalt carbonate 0.3%-0.6%, calcium iodate 0.8%-1%, manganese sulfate 20%-32%, zinc sulfate 7%-11%, zinc oxide 10%-16%; The vitamins include vitamin A 0.9%-1.3%, vitamin D 30.1%-0.3%, and vitamin E 1.0%-2.0%.

2. The anthelmintic Chinese medicine extract trace element vitamin sustained-release pill for ruminants according to claim 1, characterized in that: The extrusion molding material is prepared by mixing one or more of silicate cement, mining silicate cement, pozzolanic silicate cement, pulverized coal silicate cement and composite silicate cement in any proportion, and the extrusion molding material accounts for 9%-25%.

3. The anthelmintic Chinese medicine extract trace element vitamin sustained-release pill for ruminants according to claim 1, characterized in that: The weighted pills (2) are made by mixing iron powder and silicate cement and then extruding them into pills, wherein the iron powder accounts for 75%-85% and the silicate cement accounts for 15%-25%.

4. The anthelmintic Chinese medicine extract trace element vitamin sustained-release pill for ruminants according to claim 1, characterized in that: The mixing ratio of the weighted pills (2) to the anthelmintic pills (1) is 15-25:

100.

5. The anthelmintic Chinese medicine extract trace element vitamin sustained-release pill for ruminants according to claim 1, characterized in that: The anti-corrosion shell (3) is epoxy resin.

6. The anthelmintic Chinese medicine extract trace element vitamin sustained-release pill for ruminants according to claim 1, characterized in that: The anthelmintic pill (1) is cylindrical, 2-8 cm long and 1-3 cm in diameter.

7. The anthelmintic Chinese medicine extract trace element vitamin sustained-release pill for ruminants according to claim 1, characterized in that: The weight of the sustained-release pills is 30-120 g.

8. A method for preparing a vitamin sustained-release pill, characterized in that: The method is applied to the anthelmintic Chinese medicine extract trace element vitamin sustained-release pills for ruminants as claimed in any one of claims 1 to 7, comprising the following steps: S1, the weighed iron powder and silicate cement are mixed evenly, water is added and the mixture is continued to mix until uniform, and then the mixed material is put into a pressing mold and pressed into a cylindrical shape to obtain a weighted pill (2), the pressing pressure is 10-15 tons; S2, mix the weighed Chinese herbal extract, trace elements, vitamins and cement evenly, add appropriate amount of water and continue mixing until uniform, then put the mixed materials into a pressing mold, press into a cylindrical shape, and obtain anthelmintic pills (1), the pressing pressure is 10-15 tons; S3, stacking the above pressed weighted pills (2) and a plurality of anthelmintic pills (1), and filling them into the interior of the digestion and corrosion-resistant shell (3).

9. The method for preparing a vitamin sustained-release pill according to claim 8, characterized in that: One end of the anti-oxidation and corrosion shell (3) is sealed, the sealed end of the anti-oxidation and corrosion shell (3) matches the counterweight pill (2), and the other end of the anti-oxidation and corrosion shell (3) is open.

10. A method for using a vitamin sustained-release pill, characterized in that: The sustained-release pellets are administered into the rumen of the ruminant using a dosing device.

Citation Information

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