Pharmaceutical medicine processing, fermentation and detection integrated equipment

Abstract

The invention discloses pharmaceutical processing, fermentation and detection integrated equipment, and relates to the technical field of microbial fermentation, the pharmaceutical processing, fermentation and detection integrated equipment comprises a fermentation tank body, the inner wall of the fermentation tank body is provided with an inner heater, one side of the fermentation tank body is provided with a discharge port, the top of the fermentation tank body is provided with a top cover, and the upper part of one side of the fermentation tank body is provided with an exhaust port; and an exhaust pipe is fixedly mounted on one side of the fermentation tank body and located on one side of the exhaust port. The device disclosed by the invention has the beneficial effects that a passive collection structure is adopted, so that the internal air pressure of the fermentation tank body can be continuously increased during use to drive a pressed piston to move towards one side of the first outer mounting box; and an upper placement frame and a lower placement frame which are positioned below are triggered to rotate, and a negative pressure gas storage pipe is moved, so that the sampling mechanism can perform repeated sampling under the action of the internal gas pressure of the fermentation tank body, and subsequent workers can conveniently detect the components of gas discharged in the fermentation process of the fermentation tank body.

Description

Technical Field

[0001] The invention relates to the technical field of microbial fermentation, and in particular to a pharmaceutical drug processing, fermentation and detection integrated equipment. Background Art

[0002] Drug processing is the process of processing and fermenting drug raw materials during drug production. Some drug raw materials need to be fermented to ensure that they can get better therapeutic effects when taken. Fermentation refers to the process of preparing microbial cells themselves or direct metabolites or secondary metabolites with the help of the life activities of microorganisms under aerobic or anaerobic conditions. Generally, the fermentation process needs to be set in a relatively closed space, which can ensure the life activities of anaerobic bacteria and prevent the contamination of raw materials by miscellaneous bacteria. At the same time, the environmental data of the closed space can be controlled during drug processing, which is convenient for adjustment. During the fermentation of some raw materials, the activity of microorganisms will cause gas to be produced, thereby increasing the internal air pressure of the fermentation tank. The large air pressure will cause safety hazards. In addition, the gas components produced during the fermentation process can well reflect the fermentation status of the current raw materials. The fermentation equipment currently used is not convenient for collecting this gas. For this reason, we propose a pharmaceutical drug processing, fermentation and detection integrated equipment. Summary of the invention

[0003] In view of the deficiencies in the prior art, the present invention provides an integrated pharmaceutical drug processing, fermentation and detection device, which solves the problems raised in the above-mentioned background technology.

[0004] To achieve the above objectives, the present invention is implemented through the following technical solutions: a pharmaceutical drug processing, fermentation and detection integrated equipment, comprising a fermenter body, an inner wall of the fermenter body is provided with an internal heater, one side of the fermenter body is provided with a discharge port, a top cover is provided on the top of the fermenter body, an exhaust port is opened above one side of the fermenter body, an exhaust pipe is fixedly installed on one side of the fermenter body and on the side of the exhaust port, a sealing mechanism is provided inside the exhaust pipe, a first external installation box is fixedly installed on one side of the fermenter body, a first connecting plate is slidably connected to the inside of the fermenter body, one end of the first connecting plate extends to the inside of the first external installation box and is slidably connected thereto, the other end of the first connecting plate extends to the inside of the fermenter body and is fixedly installed with a pressure piston, an inner protective soft shell is fixedly installed on the inner wall of the fermenter body and on the outside of the pressure piston, a gas pressure linkage mechanism is provided inside the first external installation box, and a sampling mechanism is provided on one side of the fermenter body; The pneumatic linkage mechanism includes a first rack, which is fixedly mounted on one side of a first connecting plate; a first rotating shaft is rotatably connected to the inside of the first outer mounting box; a first gear is fixedly mounted on the outside of the first rotating shaft; and a first trigger switch is fixedly mounted on one side of an inner wall of the first outer mounting box.

[0005] Preferably, a first inner slide groove is provided at the top of the inner wall of the first outer mounting box, a top reset mounting strip is fixedly installed on the top of the first connecting plate, a first inner sliding block is fixedly installed on the top of the top reset mounting strip, the first inner sliding block is inserted into the interior of the first inner slide groove and is slidably connected thereto, a first spring is fixedly installed on the side of the top reset mounting strip close to the fermentation tank body, and one end of the first spring away from the top reset mounting strip is fixedly connected to the side wall of the fermentation tank body.

[0006] Preferably, the closing mechanism comprises a first closing valve and a second closing valve, both of which are located inside the exhaust pipe and are rotatably connected thereto, an upper gear box and a lower gear box are fixedly installed at the top and bottom of the exhaust pipe respectively, a third rack is slidably connected inside the upper gear box, a fifth gear and a sixth gear are rotatably connected inside the upper gear box, the fifth gear is fixedly connected to the first closing valve, the first external mounting box is connected to the second closing valve through a one-way bearing, the fifth gear and the sixth gear are both meshed with the third rack, the second rack is slidably connected inside the lower gear box, an electric telescopic rod is fixedly installed on one side of the inner wall of the lower gear box, the output end of the electric telescopic rod is fixedly connected to one side of the second rack, the third gear and the fourth gear are rotatably connected on the corresponding two sides inside the lower gear box respectively, the third gear is fixedly connected to the first closing valve, the fourth gear is connected to the second closing valve through a one-way bearing, a second rotating shaft is fixedly installed on the top of the first rotating shaft, the top of the second rotating shaft penetrates into the interior of the lower gear box and is fixedly installed with a second gear, the second gear, the third gear and the fourth gear are all meshed with the second rack.

[0007] Preferably, the sampling mechanism includes a second outer mounting box, the second outer mounting box is fixedly mounted on one side of the fermentation tank body, the bottom of the first rotating shaft passes through the first outer mounting box and is fixedly mounted with a connecting block, the bottom of the connecting block is mounted with a third rotating shaft through a one-way bearing, the bottom of the third rotating shaft extends to the inside of the second outer mounting box and is fixedly mounted with a gas storage tube placement rotating shaft, the gas storage tube placement rotating shaft is rotatably connected to the second outer mounting box, an upper placement rack and a lower placement rack are fixedly mounted on the outside of the gas storage tube placement rotating shaft, a plurality of upper placement grooves and lower placement grooves are respectively provided inside the upper placement rack and on the top of the lower placement rack The upper placement groove and the lower placement groove correspond to each other, and a negative pressure gas storage pipe is slidably placed inside the upper placement groove and the lower placement groove, a second solenoid valve is arranged inside the negative pressure gas storage pipe, a second trigger switch is fixedly installed on one side of the outer wall of the negative pressure gas storage pipe, a sampling tube is installed on one side of the fermentation tank body and above the second external installation box, one end of the sampling tube extends to the interior of the fermentation tank body, a sampling groove is opened on the top of the second external installation box, the sampling groove is connected with the sampling tube, a top trigger groove is opened on the top of the inner wall of the second external installation box and below the sampling groove, and the negative pressure gas storage pipe cooperates with the top trigger groove.

[0008] Preferably, a top touch plate is slidably connected to the inside of the top trigger groove, a second connecting plate is fixedly installed on the top of the top touch plate, the second connecting plate passes through the top of the second outer mounting box and is fixedly installed with a fourth rack, an inner closed valve plate is provided inside the sampling tube, one side of the inner closed valve plate passes through the sampling tube and is fixedly installed with a seventh gear, the fourth rack is meshed with the seventh gear, a second spring is fixedly installed on the top of the top touch plate, and the top of the second spring is fixedly connected to the inner wall of the top trigger groove.

[0009] Preferably, a magnet body is embedded in the bottom of the negative pressure gas storage pipe, and an electromagnet is embedded inside the lower placement rack and below the lower placement groove, and the negative pressure gas storage pipe is lifted upward by the repulsive force generated by the same magnetic poles after the magnet body and the electromagnet generate magnetic force.

[0010] Preferably, a bottom annular groove is provided at the bottom of the inner wall of the second outer mounting box, and a plurality of stabilizing slide blocks are fixedly installed at the bottom of the lower mounting rack. The stabilizing slide blocks are inserted into the bottom annular groove and slidably connected thereto, thereby increasing the stability of the lower mounting rack when rotating inside the second outer mounting box.

[0011] Preferably, a side discharge pipe is fixedly installed at the bottom of one side of the fermentation tank body, a bottom discharge pipe is opened at the bottom of the fermentation tank body, a discharge solenoid valve is fixedly installed at the bottom of the fermentation tank body and below the bottom discharge pipe, and a bracket is fixedly installed at the bottom of the fermentation tank body to facilitate taking out the material inside the fermentation tank body.

[0012] Preferably, a placement opening is provided on one side of the second outer installation box, and a side closed door is rotatably connected to the inside of the placement opening through a hinge. The top of the second outer installation box and the top of the side closed door are provided with matching buckles, so that the negative pressure gas storage pipe inside the second outer installation box can be taken out when it is full.

[0013] The present invention provides a pharmaceutical drug processing, fermentation and detection integrated equipment, which has the following beneficial effects: 1. The pharmaceutical drug processing, fermentation and detection integrated equipment adopts a passive collection structure. When in use, the internal air pressure of the fermenter body is continuously increased, thereby driving the pressurized piston to move to one side of the first outer mounting box, and triggering the upper and lower racks located below to rotate, so as to move the negative pressure gas storage pipe, and at the same time, a reset mechanism is provided, so that the sampling mechanism can repeat the sampling under the action of the internal air pressure of the fermenter body, and it is also convenient for subsequent staff to detect the composition of the exhaust gas during the fermentation process.

[0014] 2. The pharmaceutical drug processing, fermentation and testing integrated equipment adopts a double-layer blocking structure to seal the exhaust pipe. Such a structure can more conveniently control the air pressure inside the fermentation tank body in a linked manner, that is, when the air pressure reaches a predetermined value, active exhaust and pressure reduction work is performed, and the air pressure is re-sealed after it drops to a predetermined value, so that there is no need for staff intervention in the process, which is more convenient to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic diagram of the structure of the present invention; Figure 2 For the present invention Figure 1 A in the enlarged view; Figure 3 For the present invention Figure 1 The enlarged view of point B in the figure; Figure 4 For the present invention Figure 1 The enlarged view of point C in the figure; Figure 5 For the present invention Figure 1 The enlarged view of D in the figure; Figure 6 It is a structural schematic diagram of the closing mechanism of the present invention; Figure 7 It is a motion schematic diagram of the closing mechanism of the present invention.

[0016] In the figure: 1, fermenter body; 2, inner heater; 3, discharge port; 4, side discharge pipe; 5, bracket; 6, bottom discharge pipe; 7, discharge solenoid valve; 8, top cover; 9, exhaust port; 10, exhaust pipe; 11, first closing valve; 12, second closing valve; 13, inner protective soft shell; 14, first connecting plate; 15, pressure piston; 16, first rack; 17, first rotating shaft; 18, first gear; 19, top reset mounting strip; 20, first inner slide groove; 21, first inner slider; 22, first spring; 23, first outer mounting box; 24, first trigger switch; 25, second rotating shaft; 26, upper gear box; 27, lower gear box; 28, second gear; 29, second rack; 30, third gear; 31, fourth gear Wheel; 32, the fifth gear; 33, the sixth gear; 34, the third rack; 35, the second outer installation box; 36, the sampling tube; 37, the third rotating shaft; 38, the gas storage tube placement rotating shaft; 39, the upper placement rack; 40, the upper placement slot; 41, the lower placement rack; 42, the lower placement slot; 43, the negative pressure gas storage tube; 44, the second solenoid valve; 45, the second trigger switch; 46, the magnet body; 47, the electromagnet; 48, the top trigger slot; 49, the second connecting plate; 50, the top touch plate; 51, the second spring; 52, the fourth rack; 53, the inner closed valve plate; 54, the seventh gear; 55, the sampling slot; 56, the bottom annular groove; 57, the stabilizing slider; 58, the placement port; 59, the side closed door; 60, the connecting block; 61, the electric telescopic rod. DETAILED DESCRIPTION

[0017] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0018] See also Figures 1 to 7The present invention provides a technical solution: a pharmaceutical drug processing, fermentation and detection integrated equipment, comprising a fermentation tank body 1, a control box is arranged on the outside of the fermentation tank body 1, an inner heater 2 is arranged on the inner wall of the fermentation tank body 1, the temperature inside the fermentation tank body 1 can be regulated by the inner heater 2, and can be controlled by the control box, a discharge port 3 is arranged on one side of the fermentation tank body 1, a top cover 8 is arranged on the top of the fermentation tank body 1, an exhaust port 9 is opened above one side of the fermentation tank body 1, an exhaust pipe 10 is fixedly installed on one side of the fermentation tank body 1 and on one side of the exhaust port 9, a first outer installation box 23 is fixedly installed on one side of the fermentation tank body 1, and the inner wall of the fermentation tank body 1 is provided with a first outer installation box 23. The first connecting plate 14 is slidably connected to the fermenter body 1, one end of the first connecting plate 14 extends to the inside of the first outer installation box 23 and is slidably connected thereto, the other end of the first connecting plate 14 extends to the inside of the fermenter body 1 and is fixedly installed with a pressure piston 15, an inner protective soft shell 13 is fixedly installed on the inner wall of the fermenter body 1 and located on the outside of the pressure piston 15, a side discharge pipe 4 is fixedly installed at the bottom of one side of the fermenter body 1, a bottom discharge pipe 6 is opened at the bottom of the fermenter body 1, a discharge solenoid valve 7 is fixedly installed at the bottom of the fermenter body 1 and located below the bottom discharge pipe 6, and a bracket 5 is fixedly installed at the bottom of the fermenter body 1 to facilitate taking out the material inside the fermenter body 1; A pneumatic linkage mechanism is provided inside the first outer installation box 23, and the pneumatic linkage mechanism includes a first rack 16, which is fixedly mounted on one side of the first connecting plate 14, and the first rotating shaft 17 is rotatably connected inside the first outer installation box 23, and the first gear 18 is fixedly mounted on the outer side of the first rotating shaft 17, and a first trigger switch 24 is fixedly mounted on one side of the inner wall of the first outer installation box 23, and a first inner slide groove 20 is opened on the top of the inner wall of the first outer installation box 23, and a top reset mounting strip 19 is fixedly mounted on the top of the first connecting plate 14, and a first inner slider 21 is fixedly mounted on the top of the top reset mounting strip 19, and the first inner slider 21 is inserted into the interior of the first inner slide groove 20 and slidably connected thereto, and a first spring 22 is fixedly mounted on the side of the top reset mounting strip 19 close to the fermentation tank body 1, and one end of the first spring 22 away from the top reset mounting strip 19 is fixedly connected to the side wall of the fermentation tank body 1.

[0019] A closing mechanism is provided inside the exhaust pipe 10, and the closing mechanism includes a first closing valve 11 and a second closing valve 12. The first closing valve 11 and the second closing valve 12 are both located inside the exhaust pipe 10 and are rotatably connected thereto. An upper gear box 26 and a lower gear box 27 are fixedly installed on the top and bottom of the exhaust pipe 10, respectively. A third rack 34 is slidably connected inside the upper gear box 26. A fifth gear 32 and a sixth gear 33 are rotatably connected inside the upper gear box 26. The fifth gear 32 is fixedly connected to the first closing valve 11. The first external mounting box 23 is connected to the second closing valve 12 through a one-way bearing. The fifth gear 32 and the sixth gear 33 are both meshed with the third rack 34. The inner portion of the lower gear box 27 is connected to the third rack 34. The lower gear box 27 is slidably connected to the second rack 29, and an electric telescopic rod 61 is fixedly installed on one side of the inner wall of the lower gear box 27. The output end of the electric telescopic rod 61 is fixedly connected to one side of the second rack 29. The corresponding two sides inside the lower gear box 27 are respectively rotatably connected with the third gear 30 and the fourth gear 31. The third gear 30 is fixedly connected to the first closing valve 11, and the fourth gear 31 is connected to the second closing valve 12 through a one-way bearing. The top of the first rotating shaft 17 is fixedly installed with the second rotating shaft 25, and the top of the second rotating shaft 25 penetrates into the interior of the lower gear box 27 and is fixedly installed with the second gear 28. The second gear 28, the third gear 30 and the fourth gear 31 are all engaged with the second rack 29.

[0020] A sampling mechanism is provided on one side of the fermentation tank body 1, and the sampling mechanism includes a second outer installation box 35, and the second outer installation box 35 is fixedly installed on one side of the fermentation tank body 1. The bottom of the first rotating shaft 17 passes through the first outer installation box 23 and is fixedly installed with a connecting block 60. The bottom of the connecting block 60 is installed with a third rotating shaft 37 through a one-way bearing. The bottom of the third rotating shaft 37 extends to the inside of the second outer installation box 35 and is fixedly installed with a gas storage pipe placement rotating shaft 38. The gas storage pipe placement rotating shaft 38 is rotatably connected to the second outer installation box 35. The outer side of the gas storage pipe placement rotating shaft 38 is fixedly installed with an upper placement rack 39 and a lower placement rack 41. The upper placement rack 39 is fixedly installed with a lower placement rack 41. A plurality of upper placement grooves 40 and lower placement grooves 42 are respectively provided inside the upper placement grooves 40 and the lower placement grooves 42, and the upper placement grooves 40 and the lower placement grooves 42 correspond to each other. Negative pressure gas storage pipes 43 are slidably placed inside the upper placement grooves 40 and the lower placement grooves 42, and the bottom of the negative pressure gas storage pipe 43 is inlaid with a magnet body 46, and an electromagnet 47 is inlaid inside the lower placement rack 41 and below the lower placement grooves 42. The negative pressure gas storage pipe 43 is lifted upward by the repulsive force generated by the same magnetic poles after the magnet body 46 and the electromagnet 47 generate magnetic force, and a second solenoid valve 44 is provided inside the negative pressure gas storage pipe 43, and a first solenoid valve 44 is fixedly installed on one side of the outer wall of the negative pressure gas storage pipe 43. A second trigger switch 45 is provided, a sampling tube 36 is installed on one side of the fermentation tank body 1 and above the second outer installation box 35, one end of the sampling tube 36 extends to the inside of the fermentation tank body 1, a sampling slot 55 is provided on the top of the second outer installation box 35, the sampling slot 55 is communicated with the sampling tube 36, a top trigger slot 48 is provided on the top of the inner wall of the second outer installation box 35 and below the sampling slot 55, the negative pressure gas storage pipe 43 cooperates with the top trigger slot 48, a top touch plate 50 is slidably connected inside the top trigger slot 48, a second connecting plate 49 is fixedly installed on the top of the top touch plate 50, the second connecting plate 49 passes through the top of the second outer installation box 35 and is fixedly installed with The fourth rack 52 and the sampling tube 36 are provided with an inner closed valve plate 53, one side of the inner closed valve plate 53 passes through the sampling tube 36 and is fixedly installed with a seventh gear 54, the fourth rack 52 is meshed with the seventh gear 54, the top of the top contact plate 50 is fixedly installed with a second spring 51, the top of the second spring 51 is fixedly connected to the inner wall of the top trigger groove 48, and a bottom annular groove 56 is provided at the bottom of the inner wall of the second outer mounting box 35, and a plurality of stabilizing sliders 57 are fixedly installed at the bottom of the lower placement rack 41, and the stabilizing sliders 57 are inserted into the bottom annular groove 56 and are slidably connected thereto, thereby increasing the stability of the lower placement rack 41 rotating inside the second outer mounting box 35.

[0021] A placement opening 58 is provided on one side of the second outer installation box 35, and a side closed door 59 is rotatably connected to the inside of the placement opening 58 through a hinge. The top of the second outer installation box 35 and the top of the side closed door 59 are provided with matching buckles, and the negative pressure gas storage pipe 43 inside the second outer installation box 35 can be taken out when it is full.

[0022] In summary, when the pharmaceutical drug processing, fermentation and detection integrated equipment is used, the chemical raw materials to be fermented are first placed inside the fermentation tank body 1, and all pipelines are closed until a closed space is formed. As the raw materials continue to ferment, the air pressure inside the fermentation tank body 1 continues to increase, and due to the increase in air pressure, the pressure piston 15 moves toward the direction of the first outer mounting box 23, and the first connecting plate 14 also moves at the same time, and the first rack 16 and the first gear 18 are meshed to make the first gear 18 rotate counterclockwise {all clockwise rotation directions in this application are from a top view angle, and the arrow directions set above the fourth gear 31 and the sixth gear 33 in the figure are for this The direction of rotation is the direction set by the one-way bearing, that is, the second closing valve 12 connected thereto is not driven to rotate}, and the second rotating shaft 25 and the second gear 28 are also driven to rotate counterclockwise, and the second rack 29 is driven to move to the left. Since the second rack 29 is also meshed with the third gear 30 at this time, the third gear 30, the first closing valve 11 and the fifth gear 32 are driven to rotate at the same time. Since the fifth gear 32 is meshed with the third rack 34, the third rack 34 also moves to the right. At this time, since the sixth gear 33 and the second closing valve 12 are connected by a one-way bearing, although the sixth gear 33 rotates, it will not affect the second closing valve 12. At this time, the shape is Figure 7 As shown in ②, as the internal air pressure of the fermentation tank body 1 increases again, the first rack 16 then moves toward the first outer mounting box 23, and the second rack 29 continues to move under the influence of the second gear 28 and meshes with the fourth gear 31. At this time, since the fourth gear 31 and the second closing valve 12 are connected by a one-way bearing, the second closing valve 12 does not rotate, forming the following Figure 7As shown in ③, when the internal equipment of the exhaust pipe 10 is started, the rotation of the first rotating shaft 17 will also drive the third rotating shaft 37 and the gas storage pipe placement rotating shaft 38 to rotate, thereby driving the unused negative pressure gas storage pipe 43 inside to move to the bottom of the top trigger groove 48 until the first rack 16 contacts the first trigger switch 24. At this time, the first trigger switch 24 is used to start the electromagnet 47, so that the electromagnet 47 generates magnetic force, and the principle of repulsion generated by the same magnetic pole of the electromagnet 47 and the magnetic pole of the magnet body 46 is used to make the negative pressure gas storage pipe 43 move to the bottom of the top trigger groove 48. The negative pressure gas storage pipe 43 is lifted upward, and at this time, the second trigger switch 45 contacts the bottom of the second outer installation box 35, thereby starting the second solenoid valve 44, allowing the second solenoid valve 44 to open, and at this time, the upward lifting of the negative pressure gas storage pipe 43 is used to squeeze the top touch plate 50, so that the top touch plate 50 moves upward, and at this time, the engagement of the fourth rack 52 and the seventh gear 54 is used to rotate the inner closed valve plate 53, and at this time, the sampling tube 36 is connected internally, and the gas inside the fermentation tank body 1 will flow into the sampling slot 55 and The top trigger groove 48 is touched, and the gas is sucked into the negative pressure gas storage pipe 43 by using the negative pressure gas storage pipe 43 with negative pressure inside. After the electromagnet 47 is powered for 2 seconds, the power is stopped. At this time, the gas sample in the negative pressure gas storage pipe 43 is collected, and the negative pressure gas storage pipe 43 falls due to the loss of repulsion, and the second solenoid valve 44 returns to the closed state to ensure the purity of the sample. The top touch plate 50 also falls due to the lack of bottom support, so that the inner closed valve plate 53 returns to the initial state again, and the sampling tube 36 is closed, thus completing the collection of the gas sample. At the same time, the first rack 16 is also used to contact the first trigger switch 24 to start the electric telescopic rod 61, and the electric telescopic rod 61 is used to push the second rack 29 to the right. At this time, the meshing of the second rack 29 and the fourth gear 31 drives the fourth gear 31 to rotate, and the rotation of the fourth gear 31 will drive the second closing valve 12 to rotate, so that the exhaust pipe 10 is connected to the inside, and the excess gas can flow out along the exhaust pipe 10 to avoid the danger caused by high pressure, forming a Figure 7As shown in ④, as the internal air pressure of the fermentation tank body 1 decreases, the pressure inside the fermentation tank body 1 applied to the pressurized piston 15 gradually becomes smaller than the pull given by the first spring 22, so that the first rack 16 moves toward the inside of the fermentation tank body 1, and at the same time, the electric telescopic rod 61 is in a standby state, passively extending and shortening with the movement of the second rack 29. At this time, the first gear 18 reverses. Since the connecting block 60 is connected to the third rotating shaft 37 through a one-way bearing, this design can avoid the reverse rotation of the rotating shaft 38 of the gas storage tube. When the first gear 18 When reversing, the second gear 28 will also be driven to reverse, until the second rack 29 is meshed with the third gear 30 under the influence of the rotation of the second gear 28. At this time, the third gear 30 will simultaneously drive the first closing valve 11 and the fifth gear 32 to rotate under the influence of the second rack 29, thereby pulling the third rack 34 to the right. At this time, while driving the sixth gear 33 to rotate, the second closing valve 12 will also rotate with the sixth gear 33, so that the first closing valve 11 and the second closing valve 12 are simultaneously rotated 90° to achieve the effect of simultaneously closing the exhaust pipe 10, forming a Figure 7 As shown in ⑤, in this state, the interior of the fermentation tank body 1 is completely closed, and the air pressure continues to rise again, thereby achieving the cycle of the above steps. When the negative pressure gas storage pipe 43 located inside the second outer installation box 35 is completely used, the side closed door 59 is opened to take the object out of the second outer installation box 35, so that the gas generated by the fermentation situation in different time periods can be detected, thereby recording the fermentation situation.

[0023] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A pharmaceutical drug processing, fermentation and detection integrated device, comprising a fermentation tank body (1), characterized in that: The inner wall of the fermentation tank body (1) is provided with an internal heater (2); a discharge port (3) is provided on one side of the fermentation tank body (1); a top cover (8) is provided on the top of the fermentation tank body (1); an exhaust port (9) is provided above one side of the fermentation tank body (1); an exhaust pipe (10) is fixedly installed on one side of the fermentation tank body (1) and located on the side of the exhaust port (9); a sealing mechanism is provided inside the exhaust pipe (10); a first external installation box (23) is fixedly installed on one side of the fermentation tank body (1); and the fermentation tank body (1) is provided with a plurality of external installation boxes (23). A first connecting plate (14) is slidably connected to the interior of the fermenter body (1), one end of the first connecting plate (14) extends to the interior of a first external installation box (23) and is slidably connected thereto, the other end of the first connecting plate (14) extends to the interior of the fermenter body (1) and is fixedly mounted with a pressure-bearing piston (15), an inner protective soft shell (13) is fixedly mounted on the inner wall of the fermenter body (1) and on the outer side of the pressure-bearing piston (15), a pneumatic linkage mechanism is arranged inside the first external installation box (23), and a sampling mechanism is arranged on one side of the fermenter body (1); The pneumatic linkage mechanism comprises a first rack (16), the first rack (16) being fixedly mounted on one side of a first connecting plate (14), a first rotating shaft (17) being rotatably connected inside the first outer mounting box (23), a first gear (18) being fixedly mounted on the outer side of the first rotating shaft (17), and a first trigger switch (24) being fixedly mounted on one side of an inner wall of the first outer mounting box (23).

2. The pharmaceutical drug processing, fermentation and detection integrated equipment according to claim 1, characterized in that: A first inner slide groove (20) is provided at the top of the inner wall of the first outer installation box (23); a top reset installation strip (19) is fixedly installed at the top of the first connecting plate (14); a first inner slide block (21) is fixedly installed at the top of the top reset installation strip (19); the first inner slide block (21) is inserted into the first inner slide groove (20) and is slidably connected thereto; a first spring (22) is fixedly installed on a side of the top reset installation strip (19) close to the fermentation tank body (1); and an end of the first spring (22) away from the top reset installation strip (19) is fixedly connected to the side wall of the fermentation tank body (1).

3. The pharmaceutical drug processing, fermentation and detection integrated equipment according to claim 1, characterized in that: The sealing mechanism comprises a first sealing valve (11) and a second sealing valve (12), the first sealing valve (11) and the second sealing valve (12) are both located inside the exhaust pipe (10) and are rotatably connected thereto, an upper gear box (26) and a lower gear box (27) are respectively fixedly mounted on the top and bottom of the exhaust pipe (10), a third rack (34) is slidably connected inside the upper gear box (26), a fifth gear (32) and a sixth gear (33) are rotatably connected inside the upper gear box (26), the fifth gear (32) is fixedly connected to the first sealing valve (11), the first external mounting box (23) is connected to the second sealing valve (12) via a one-way bearing, the fifth gear (32) and the sixth gear (33) are both meshed with the third rack (34), the lower gear box (27) is slidably connected inside The lower gear box (27) has a second rack (29), an electric telescopic rod (61) is fixedly mounted on one side of the inner wall of the lower gear box (27), an output end of the electric telescopic rod (61) is fixedly connected to one side of the second rack (29), and corresponding two sides inside the lower gear box (27) are rotatably connected to a third gear (30) and a fourth gear (31), the third gear (30) is fixedly connected to the first closing valve (11), and the fourth gear (31) is connected to the second closing valve (12) via a one-way bearing, a second rotating shaft (25) is fixedly mounted on the top of the first rotating shaft (17), the top of the second rotating shaft (25) penetrates into the interior of the lower gear box (27) and is fixedly mounted with a second gear (28), and the second gear (28), the third gear (30) and the fourth gear (31) are all meshed with the second rack (29).

4. The pharmaceutical drug processing, fermentation and detection integrated equipment according to claim 1, characterized in that: The sampling mechanism comprises a second outer installation box (35), the second outer installation box (35) is fixedly installed on one side of the fermentation tank body (1), the bottom of the first rotating shaft (17) passes through the first outer installation box (23) and is fixedly installed with a connecting block (60), the bottom of the connecting block (60) is installed with a third rotating shaft (37) through a one-way bearing, the bottom of the third rotating shaft (37) extends to the inside of the second outer installation box (35) and is fixedly installed with a gas storage pipe placement rotating shaft (38), the gas storage pipe placement rotating shaft (38) is rotatably connected to the second outer installation box (35), an upper placement rack (39) and a lower placement rack (41) are fixedly installed on the outside of the gas storage pipe placement rotating shaft (38), the inside of the upper placement rack (39) and the top of the lower placement rack (41) are respectively provided with a plurality of upper placement grooves (40) and lower placement grooves (42), the upper placement rack (39) and the top of the lower placement rack (41) are respectively provided with a plurality of upper placement grooves (40) and a plurality of lower placement grooves (42), The groove (40) corresponds to the lower placement groove (42), and a negative pressure gas storage pipe (43) is slidably placed inside the upper placement groove (40) and the lower placement groove (42). A second solenoid valve (44) is arranged inside the negative pressure gas storage pipe (43). A second trigger switch (45) is fixedly installed on one side of the outer wall of the negative pressure gas storage pipe (43). A sampling tube (36) is installed on one side of the fermentation tank body (1) and above the second outer installation box (35). One end of the sampling tube (36) extends into the interior of the fermentation tank body (1). A sampling groove (55) is provided on the top of the second outer installation box (35). The sampling groove (55) is communicated with the sampling tube (36). A top trigger groove (48) is provided on the top of the inner wall of the second outer installation box (35) and below the sampling groove (55). The negative pressure gas storage pipe (43) cooperates with the top trigger groove (48).

5. The pharmaceutical drug processing, fermentation and detection integrated equipment according to claim 4, characterized in that: A top contact plate (50) is slidably connected inside the top trigger groove (48), a second connecting plate (49) is fixedly mounted on the top of the top touch plate (50), the second connecting plate (49) passes through the top of the second outer mounting box (35) and is fixedly mounted with a fourth rack (52), an inner closed valve plate (53) is arranged inside the sampling tube (36), one side of the inner closed valve plate (53) passes through the sampling tube (36) and is fixedly mounted with a seventh gear (54), the fourth rack (52) meshes with the seventh gear (54), a second spring (51) is fixedly mounted on the top of the top touch plate (50), and the top of the second spring (51) is fixedly connected to the inner wall of the top trigger groove (48).

6. The pharmaceutical drug processing, fermentation and detection integrated equipment according to claim 1, characterized in that: A magnet body (46) is embedded in the bottom of the negative pressure gas storage pipe (43), and an electromagnet (47) is embedded inside the lower placement frame (41) and below the lower placement groove (42).

7. The pharmaceutical drug processing, fermentation and detection integrated equipment according to claim 1, characterized in that: A bottom annular groove (56) is provided at the bottom of the inner wall of the second outer installation box (35), and a plurality of stabilizing slide blocks (57) are fixedly installed at the bottom of the lower placement rack (41). The stabilizing slide blocks (57) are inserted into the bottom annular groove (56) and are slidably connected thereto.

8. The pharmaceutical drug processing, fermentation and detection integrated equipment according to claim 1, characterized in that: A side discharge pipe (4) is fixedly mounted on the bottom of one side of the fermentation tank body (1); a bottom discharge pipe (6) is provided at the bottom of the fermentation tank body (1); a discharge solenoid valve (7) is fixedly mounted at the bottom of the fermentation tank body (1) and below the bottom discharge pipe (6); and a bracket (5) is fixedly mounted at the bottom of the fermentation tank body (1).

9. The pharmaceutical drug processing, fermentation and detection integrated equipment according to claim 1, characterized in that: A placement opening (58) is provided on one side of the second outer installation box (35), the interior of the placement opening (58) is rotatably connected to a side closed door (59) via a hinge, and mutually matching buckles are provided on the top of the second outer installation box (35) and the top of the side closed door (59).

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