Ball pricking needle for uniform injection in tumor

Abstract

The invention relates to the technical field of medical instruments, in particular to a ball pricking needle for uniform injection in tumors, which comprises a puncture part and a handheld part, the handheld part comprises an upper tube body, a lower tube body and a connecting arm connected between the upper tube body and the lower tube body; the puncture part comprises an outer tube, a core needle movably inserted into the outer tube and a puncture needle assembly connected between the outer tube and the core needle, the core needle is in threaded connection with a nut and sleeved with a sealing ring, the nut is rotationally connected between the upper tube body and the lower tube body and located on the inner side of the connecting arm, and the sealing ring is sleeved with the nut. The sealing ring is in sealing contact with the inner wall of the outer pipe, the upper end of the outer pipe is connected with the lower end of the lower pipe body, and the axis of the outer pipe coincides with the axis of the upper pipe body and the axis of the lower pipe body. One-time puncture and multi-point injection in a tumor can be achieved more easily, liquid medicine can be prevented from flowing out in the injection process, organs around the tumor are not prone to being damaged in the injection process, and use is safer.

Description

Technical Field

[0001] The invention relates to the technical field of medical instruments, and in particular to a pricking ball needle for uniform intratumor injection. Background Art

[0002] Chemical ablation is a commonly used minimally invasive interventional treatment for tumors. Under the guidance of imaging, chemical ablation drugs are directly injected into tumor tissue through percutaneous puncture to achieve the purpose of killing tumors. Currently, the most commonly used chemical ablation needle in clinical practice is represented by the PTC-B puncture needle (interventional puncture needle) State Food and Drug Administration Medical Device (Enterprise) No. 2010 3152572. This type of puncture needle has a single lumen and end hole, and the injection range of the drug is small and limited, so that the drug cannot be evenly diffused in the tumor.

[0003] The Chinese invention patent with application number CN201910724906.0 discloses a fluoroscopic lower airway tumor drug injection device, including an outer sheath and an inner push rod, the inner push rod is coaxially inserted in the outer sheath, the rear end of the inner push rod is provided with a thumb buckle, the rear end of the outer sheath is provided with an index finger buckle, the length of the inner push rod is greater than the outer sheath, and the front end of the inner push rod is fixed with a mounting ring, the mounting ring is hexagonal, and the mounting ring is installed with a drug injection assembly. The technology provided by the invention controls the index finger to push the injection needle forward out of the outer sheath, and the injection needle is expanded and punctured into the tumor tissue by expanding the airbag through drug injection. The injection needles are evenly distributed, and the chemotherapy drugs can be evenly injected into the tumor tissue, which has a good chemotherapy effect, avoids multiple punctures of the tumor tissue, reduces the operation steps, and avoids tumor spread caused by multiple punctures.

[0004] However, in the experimental test of the above patent technology, it was found that the technology still has the following problems: 1. The front end of the outer sheath needs to be opened with a larger opening to facilitate the entry and exit of the injection component. During the insertion process, the front end of the outer sheath is not smooth, the puncture resistance is large, and the texture of the tumor tissue is relatively hard, making puncture difficult, and the larger end opening wall is also easy to shear the normal tissue and / or tumor tissue passing through, so that the puncture process is damaged, and it is easy to cause problems such as overflow during the injection process and after the needle is withdrawn, and tumor cell metastasis; 2. Because the injection needle is extended backward and the angle between the injection needle and the linkage rod 7 is 45°-60°, when the injection needle penetrates the tumor tissue, although the gas in the injection balloon has been discharged, the injection needle that has penetrated into the tumor tissue will still be hooked with the tumor and is not easy to detach. Although the four linkage rods 7 can be retracted into the outer sheath 1, the injection needle will hook and break the tumor and normal tissue organs during the withdrawal process, and the damage will be large, and it is also easy to cause tumor spread. Summary of the invention

[0005] The purpose of the present invention includes providing a puncture ball needle which can perform multiple-point injection in a tumor at one time, can prevent the outflow of drug solution during the injection process, and is safe to use for uniform injection in the tumor.

[0006] In order to achieve the above object, the present invention has the following technical solutions:

[0007] The present invention provides a puncture ball needle for uniform intratumor injection, comprising a puncture part and a hand-held part, wherein the hand-held part comprises an upper tube body, a lower tube body, and a connecting arm connected between the upper tube body and the lower tube body;

[0008] The puncture part includes an outer tube, a core needle movably inserted in the outer tube, and a puncture needle assembly connected between the outer tube and the core needle. The core needle is threaded with a nut and sleeved with a sealing ring. The nut is rotatably connected between the upper tube body and the lower tube body and is located on the inner side of the connecting arm. The sealing ring is in sealing contact with the inner wall of the outer tube. The upper end of the outer tube is connected to the lower end of the lower tube body, and the axis of the outer tube coincides with the axis of the upper tube body and the lower tube body.

[0009] Preferably, the core needle comprises a syringe connector, a stop tube section, a threaded tube section, a lower tube section, a grooved tube section, a puncture section and a flow channel at least connecting the syringe connector, the stop tube section, the threaded tube section and the lower tube section.

[0010] The syringe connector is a convex edge that is the same as an existing conventional syringe needle and can be connected to an existing syringe.

[0011] The anti-rotation pipe section is connected between the syringe connector and the upper end of the threaded pipe section, and is slidably inserted into the upper pipe body;

[0012] The threaded pipe section is threadedly connected with the nut;

[0013] The lower part of the lower pipe section is provided with a sealing ring groove, a side hole and an elastic pipe end groove in sequence from top to bottom, the side hole is connected to the flow channel, and the lower pipe section is connected between the lower end of the threaded pipe section and the upper end of the grooved pipe section;

[0014] A plurality of grooves are arranged on the outer peripheral surface of the grooved tube section, and the lower end of the grooved tube section is connected to the upper end of the puncture section.

[0015] Preferably, the number of the grooves is 4, and the 4 grooves are evenly arranged outside the grooved pipe section.

[0016] Preferably, a needle hole is provided on the side of the puncture section, and the needle hole is communicated with the flow channel and the side hole.

[0017] Preferably, the diameter of the side hole is larger than the diameter of the pinhole.

[0018] Preferably, the needle assembly includes an elastomeric tube and a plurality of needles vertically fixedly connected to the elastomeric tube, the holes on the needles are in communication with the inside and outside of the elastomeric tube, and the needles can enter and exit the groove as the elastic tube body flips on the groove tube section; one end of the elastomeric tube is connected to the lower part of the outer tube, and the other end is connected to the elastic tube end slot on the core needle, and the elastomeric tube can be tightly fitted on the groove tube section.

[0019] Preferably, the diameter of the elastic tube gradually increases from the end connected to the elastic tube end slot to the end connected to the outer tube end.

[0020] Preferably, the inner diameter of the elastomeric tube is smaller than the outer diameter of the grooved tube section on the core needle.

[0021] Preferably, the elastomeric tube is a rubber tube.

[0022] Preferably, the length of the needle is greater than 5 times the wall thickness of the outer tube, so that when the lower end of the needle is against the lower tube section, the liquid outlet of the needle is higher than the outside of the outer tube, and the liquid outlet of the needle can penetrate the tumor.

[0023] Preferably, the liquid outlet hole on the puncture needle is located on the side of the puncture needle.

[0024] Preferably, the gap between the outer surface of the core needle and the inner wall of the outer tube is greater than the thickness of the elastomer tube.

[0025] Preferably, the radial cross-section of the anti-rotation pipe section is square in shape.

[0026] Due to the adoption of the above technical solution, the advantages of the present invention are:

[0027] 1. After the puncture ball needle for uniform intratumor injection provided by the present invention is inserted into the interior of the tumor, the multiple needles on the puncture section and the needle assembly can be dispersed to penetrate into different areas inside the tumor. After the injected drug flows through the flow channel, it can be injected into multiple points inside the tumor from the needle holes of the multiple needles and the puncture section, thereby achieving more uniform drug administration at multiple points in the tumor through one puncture.

[0028] 2. The puncture ball needle for uniform intratumor injection provided by the present invention can deploy the puncture needle on the puncture needle assembly by rotating the nut clockwise after the puncture portion punctures the interior of the tumor, and can also re-enter the puncture needle into the groove of the groove tube section by rotating the nut counterclockwise after the intratumor injection is completed. It is not easy for the puncture needle to scratch the normal tissue outside the tumor, and it is safe to use;

[0029] 3. After the liquid medicine is injected into the puncture needle assembly provided by the present invention, the elastic tube deforms and expands under the pressure of the liquid medicine, so that the outer wall of the elastic tube is closely attached to the tumor, thereby sealing the puncture needle opening and the needle hole, and preventing the liquid medicine from flowing out during the injection process.

[0030] 4. The needle hole of the puncture section provided by the thorn ball needle for uniform intratumor injection provided by the present invention is located on the side of the puncture section, and the caliber can be smaller, so puncture is easier and the puncture wound surface is smaller.

[0031] 5. In the process of rotating the nut clockwise to extend the core needle, the lower tube section gradually moves to the lower end of the needle, pushing the tip of the needle into the tumor, making it easier for the needle to penetrate the tumor; in the process of rotating the nut counterclockwise to retract the core needle, the end of the elastic tube connected to the core needle moves backward with the core needle and gradually sleeves on the groove tube section. At the same time, the elastic tube pulls the needle on it out of the tumor and transfers it to the groove of the groove tube section, so that the needle is separated from the tumor and is retracted into the groove.

[0032] 6. The thorn ball needle for uniform intratumor injection provided by the present invention has a simple structure, is easy to manufacture, and is convenient to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for use in the embodiments are briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without creative work.

[0034] Figure 1 A schematic front view of the overall structure of a thorn ball needle for uniform intratumor injection provided by an embodiment of the present invention;

[0035] Figure 2 for Figure 1 A top view schematic diagram of

[0036] Figure 3 for Figure 1 A schematic diagram of the core needle main view in FIG.

[0037] Figure 4 for Figure 3 AA sectional view of FIG.

[0038] Figure 5 for Figure 1 A schematic axial cross-sectional view of the lower part of the puncture portion;

[0039] Figure 6 For the general Figure 1 Schematic diagram of the state after the puncture part in the figure pierces the inside of the tumor and then the nut is screwed clockwise;

[0040] Figure 7 For Figure 6 Schematic diagram of the state after the drug solution is injected into the flow channel.

[0041] In the figure: 1, puncture needle; 2, tumor; 3, nut; 4, sealing ring; 5, gap; 10, hand-held part; 11, upper tube body; 12, connecting arm; 13, lower tube body; 20, puncture part; 21, outer tube; 22, puncture needle assembly; 221, elastic tube; 222, puncture needle; 23, core needle; 231, syringe connector; 232, anti-rotation tube section; 233, threaded tube section; 234, lower tube section; 2341, sealing ring slot; 2342, side hole; 2343, elastic tube end slot; 235, grooved tube section; 2351, groove; 236, puncture section; 2361, needle hole; 237, flow channel. DETAILED DESCRIPTION

[0042] In the description of the present invention, it should be noted that if the terms "upper", "lower", "inside", "outside", "left", "right", "front", "back" and the like appear to indicate directions or positional relationships, they are based on the directions or positional relationships shown in the accompanying drawings, or are the directions or positional relationships in which the inventive product is usually placed when in use. These are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore should not be understood as a limitation on the present invention.

[0043] It should be noted that, in the absence of conflict, the features in the embodiments of the present invention may be combined with each other.

[0044] The specific implementation method is now described as follows:

[0045] An embodiment of a thorn ball needle for uniform intratumoral injection provided by the present invention is shown in Figure 1 , Figure 2 , comprising a puncture part 20 and a hand-held part 10, wherein the hand-held part 10 comprises an upper tube body 11, a lower tube body 13, and a connecting arm 12 connected between the upper tube body 11 and the lower tube body 13;

[0046] The puncture part 20 includes an outer tube 21, a core needle 23 movably inserted in the outer tube 21, and a puncture needle assembly 22 connected between the outer tube 21 and the core needle 23. The upper end of the outer tube 21 is connected to the lower end of the lower tube body 13, and the axis of the outer tube 21 coincides with the axis of the upper tube body 11 and the lower tube body 13.

[0047] The core needle 23 includes a syringe connector 231, a stop tube section 232, a threaded tube section 233, a lower tube section 234, a grooved tube section 235, a puncture section 236 and a flow channel 237. The radial cross-section of the stop tube section 232 is square in shape. The stop tube section 232 is connected between the syringe connector 231 and the upper end of the threaded tube section 233, and is slidably inserted in the upper tube body 11; the outer diameter of the threaded tube section 233 is smaller than the outer diameter of the stop tube section 232 and the outer diameter of the lower tube section 234, and a nut 3 is threaded on the threaded tube section 233, and the nut 3 is rotatably connected between the upper tube body 11 and the lower tube body 13, and is located on the inner side of the connecting arm 12; the lower part of the lower tube section 234 is provided with a sealing ring groove 2341, a side hole 2342 and an elastic tube end groove 2343 from top to bottom, and the sealing ring groove 2 A sealing ring 4 is clamped in 341, and the outer peripheral surface of the sealing ring 4 is in sealing contact with the inner wall of the outer tube 21. The lower tube section 234 is connected between the lower end of the threaded tube section 233 and the upper end of the grooved tube section 235; four grooves 2351 for accommodating the puncture needle 222 are evenly arranged on the outer peripheral surface of the grooved tube section 235, and the lower end of the grooved tube section 235 is connected to the upper end of the puncture section 23; a needle hole 2361 is arranged on the side of the puncture section 236; the flow channel 237 passes through the anti-rotation tube section 232, the threaded tube section 233, the lower tube section 234, the grooved tube section 235 and the puncture section 236, and connects the syringe connector 231, the side hole 2342 and the needle hole 2361, the aperture of the side hole 2342 is larger than the diameter of the flow channel 237, and the aperture of the needle hole 2361 is equal to the diameter of the flow channel 237, see Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 .

[0048] The needle assembly 22 includes an elastomeric tube 221 and 12 needles 222 vertically fixedly connected to the elastomeric tube 221. The holes on the needles 222 are connected to the inside and outside of the elastomeric tube 221. The liquid outlet holes on the needles 222 are located on the side of the needles 222. The distance from the lower edge of the liquid outlet hole to the lower end of the needle 222 is greater than the distance from the outside of the lower tube section 234 to the outside of the outer tube 21. One end of the elastomeric tube 221 is fixedly connected to the lower part of the outer tube 21, and the other end is connected to the elastic tube end slot 2343. The inner diameter of the elastomeric tube 221 is smaller than the outer diameter of the slot tube section 235. The wall thickness of the elastomeric tube 221 is smaller than the gap distance between the outside of the lower tube section 234 and the inner wall of the outer tube 21. Figure 1 , Figure 5 , Figure 6 , Figure 7 .

[0049] In this embodiment, the syringe connector 231 is a convex edge that is the same as an existing conventional syringe needle and can be connected to an existing syringe; the diameter of the elastic tube 221 gradually increases from the end connected to the elastic tube end slot 2343 to the end connected to the outer tube 21; the elastomeric tube 221 is a rubber tube with a hardness of 65 degrees.

[0050] The principle of the needle 222 provided by the present invention piercing the tumor 2 and retracting to the groove 2351 is as follows:

[0051] After the puncture portion 20 of the present invention has pierced the tumor 2, when the nut 3 is rotated clockwise to extend the core needle 23, the elastic tube 221 body tightly sleeved on the groove tube section 235 is gradually pulled backward relative to the connecting end of the outer tube 21, and the elastic tube 221 body gradually turns outward from close to the puncture section 236, so that the tip of the needle 222 gradually turns upward and moves out of the groove 2351, and the lower tube section 234 gradually moves to the lower end of the needle 222 (that is, the body of the elastic tube 221 gradually sleeves on the lower tube section 2 34), during this process, the lower end of the needle 222 is pressed against the outside of the lower tube section 234, so that the tip of the needle 222 is pushed and inserted into the tumor 2. In addition, since the liquid outlet of the needle 222 penetrates into the tumor 2, when the liquid medicine is injected through the syringe connector 231, the liquid medicine enters the gap 5 from the flow channel 237 (under the action of the rebound force of the elastic tube 221, the inner surface of the elastic tube 221 can be attached to the lower tube section 234, and the space of the gap 5 can be small enough to be ignored), the liquid outlet and the needle hole 2361 of the needle 222 enter the tumor, and since the tumor The body is compact, so that the injection is slow. The increased injection pressure makes the elastic tube 221 expand. On the one hand, the expanded elastic tube 221 further carries the puncture needle 222 into the tumor. On the other hand, the wall of the expanded elastic tube 221 is close to the puncture entrance inside the tumor 2, blocking and sealing the puncture passage, at least preventing the liquid medicine from flowing out of the puncture entrance during the injection process. When the injection is completed, the nut 3 is rotated counterclockwise to retract the core needle 23. The end of the elastic tube 221 connected to the core needle 23 moves backward with the core needle 23. Since there is still residual material in the elastic tube 221, the elastic tube 221 is The resistance of the drug liquid prevents the elastic tube 221 from retracting, and because the diameter of the elastic tube 221 gradually increases from the end connected to the elastic tube end slot 2343 to the end connected to the outer tube 21, the body of the elastic tube 221 can be gradually turned over and put back into the slot tube section 235 again. At the same time, the elastic tube 221 pulls the puncture needle 222 connected thereto out of the tumor 2 and turns it into the groove 2351 of the groove tube section 235, so that the puncture needle 222 is separated from the tumor 2 and is stored in the groove 2351, and then it can be withdrawn from the human body to complete the intratumoral injection in the present invention.

[0052] The method of using the present invention:

[0053] S1, connecting the syringe filled with liquid medicine to the syringe connector 231;

[0054] S2, the operator holds the lower tube body 13 and, under the guidance of the image, punctures the puncture segment 236 into the tumor 2 through the skin until the elastic tube 221 completely enters the tumor 2;

[0055] S3, rotating the nut 3 clockwise until it cannot be rotated (the needle 222 extends out of the outer tube 21 and penetrates the tumor 2);

[0056] S4, operate the syringe to inject the drug into the tumor 2 through the flow channel 237, and the drug enters the tumor 2 through the needle hole 2361 and the puncture needle 222;

[0057] S5, after the injection is completed, the nut 3 is rotated counterclockwise until it cannot be rotated (the puncture needle 222 is separated from the tumor 2 and rotated to be stored in the groove 2351 and the puncture section 236 is retracted to be close to the end of the outer tube 21);

[0058] S6: The operator holds the lower tube body 13 and pulls out the puncture part 20.

[0059] The above embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not intended to limit the embodiments of the present invention. For those skilled in the art, other different forms of changes or modifications can be made based on the above description. It is impossible to list all the embodiments here. Any obvious changes or modifications derived from the technical solution of the present invention are still within the scope of protection of the present invention.

Claims

1. A puncture ball needle (1) for uniform intratumoral injection, comprising a puncture portion (20) and a hand-held portion (10), characterized in that: The handheld part (10) comprises an upper tube body (11), a lower tube body (13), and a connecting arm (12) connected between the upper tube body (11) and the lower tube body (13); The puncture part (20) comprises an outer tube (21), a core needle (23) movably inserted in the outer tube (21), and a puncture needle assembly (22) connected between the outer tube (21) and the core needle (23); a nut (3) is threadedly connected to the core needle (23) and a sealing ring (4) is sleeved thereon; the nut (3) is rotatably connected between the upper tube body (11) and the lower tube body (13) and is located on the inner side of the connecting arm (12); the sealing ring (4) is in sealing contact with the inner wall of the outer tube (21); the upper end of the outer tube (21) is connected to the lower end of the lower tube body (13); and the axis of the outer tube (21) coincides with the axis of the upper tube body (11) and the lower tube body (13).

2. The pricking ball needle (1) for uniform intratumoral injection according to claim 1, characterized in that: The core needle (23) comprises a syringe connector (231), a stop tube section (232), a threaded tube section (233), a lower tube section (234), a grooved tube section (235), a puncture section (236), and a flow channel (237) at least connecting the syringe connector (231), the stop tube section (232), the threaded tube section (233), and the lower tube section (234). The anti-rotation pipe section (232) is connected between the syringe connector (231) and the upper end of the threaded pipe section (233), and is slidably inserted into the upper pipe body (11); The threaded pipe section (233) is threadedly connected to the nut (3); The lower portion of the lower pipe section (234) is provided with a sealing ring groove (2341), a side hole (2342) and an elastic pipe end groove (2343) in sequence from top to bottom, the side hole (2342) is connected to the flow channel (237), and the lower pipe section (234) is connected between the lower end of the threaded pipe section (233) and the upper end of the grooved pipe section (235); A plurality of grooves (2351) are provided on the outer peripheral surface of the grooved tube section (235), and the lower end of the grooved tube section (235) is connected to the upper end of the puncture section (236).

3. The pricking ball needle (1) for uniform intratumoral injection according to claim 2, characterized in that: A needle hole (2361) is provided on the side of the puncture section (236), and the needle hole (2361) is communicated with the flow channel (237).

4. The pricking ball needle (1) for uniform intratumoral injection according to claim 2, characterized in that: The aperture of the side hole (2342) is larger than the aperture of the flow channel (237).

5. The pricking ball needle (1) for uniform intratumoral injection according to claim 1, characterized in that: The needle assembly (22) comprises an elastomeric tube (221) and a plurality of needles (222) vertically fixedly connected to the elastomeric tube (221); the holes on the needles (222) are in communication with the inside and outside of the elastomeric tube (221); one end of the elastomeric tube (221) is connected to the lower part of the outer tube (21), and the other end is connected to the core needle (23).

6. The pricking ball needle (1) for uniform intratumoral injection according to claim 5, characterized in that: The inner diameter of the elastic tube (221) is smaller than the outer diameter of the core needle (23).

7. The pricking ball needle (1) for uniform intratumoral injection according to claim 5, characterized in that: The length of the puncture needle (222) is greater than 5 times the wall thickness of the outer tube (21).

8. The pricking ball needle (1) for uniform intratumoral injection according to claim 5 or 7, characterized in that: The liquid outlet hole on the puncture needle (222) is located on the side of the puncture needle (222).

9. The pricking ball needle (1) for uniform intratumoral injection according to claim 5, characterized in that: The gap between the outer surface of the core needle (23) and the inner wall of the outer tube (21) is greater than the thickness of the elastomer tube (221).

10. The pricking ball needle (1) for uniform intratumoral injection according to claim 2, characterized in that: The radial cross-section of the anti-rotation pipe section (232) is in the shape of a square.

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