Functional composition and application thereof in enhancing immunity and relieving visual fatigue

Abstract

The invention relates to a functional composition and application thereof in enhancing immunity and relieving visual fatigue, and belongs to the technical field of food. In order to solve the problem that scientific and reasonable compatibility capable of improving the efficacy of the composition is lacked among novel functional components, the invention provides a functional composition and application thereof in enhancing immunity and relieving visual fatigue. The bovine colostrum powder, the blueberry juice powder, the blueberry anthocyanin, the chrysanthemum powder and the Chinese wolfberry fruit powder are taken as natural active functional components, and the synergistic interaction effects of the functional components in the aspects of enhancing immunity and relieving visual fatigue are fully exerted through scientific and reasonable compatibility; the functional composition which is natural, safe, healthy and effective and contributes to enhancing the immunity of the organism and relieving visual fatigue is developed. When the functional composition provided by the invention is applied to food or health care products, the snack degree of homology of medicine and food in the aspects of food and health care products can be greatly improved, and meanwhile, the functional composition also has the characteristics of being convenient to carry and eat.

Description

Technical Field

[0001] The invention belongs to the field of food technology, and in particular relates to a functional composition and application thereof in enhancing immunity and alleviating visual fatigue. Background Art

[0002] In the fast-paced and high-pressure modern life, people are paying more and more attention to health and wellness. As an important part of the health industry, functional compositions have become a hot topic of current research due to their unique health-promoting effects. Such compositions are designed to achieve specific health benefits, such as enhancing immunity, by scientifically proportioning a variety of functional ingredients. Common functional ingredients that enhance immunity mainly include trace elements such as vitamin C, vitamin E, zinc, and selenium, as well as natural extracts such as polysaccharides and flavonoids. These ingredients effectively enhance the body's immunity through various pathways.

[0003] With the rapid development of science and technology and the accelerated pace of life, modern people are increasingly dependent on electronic products, such as mobile phones and computers. Staring at the screen for a long time not only consumes a lot of vision, but also causes visual fatigue. In order to solve this problem, many functional ingredients for visual fatigue have emerged on the market. These ingredients work together through multiple mechanisms to effectively relieve visual fatigue. Lutein and zeaxanthin, as important components of the retinal macular area, can absorb blue light and reduce light damage; vitamin A participates in the synthesis of retinal rhodopsin to maintain normal visual function.

[0004] With the advancement of science and technology and the diversification of consumer demand, the research and development of functional compositions has become increasingly sophisticated, involving not only the optimization and utilization of traditional ingredients, but also the exploration and development of new ingredients, such as bovine colostrum powder, blueberry anthocyanins, etc. However, the effects of the mutual compatibility between various new ingredients are unpredictable, and the absorption, distribution, metabolism and excretion of functional components in the body may be affected by other components. This unpredictable influence may lead to mutual enhancement of functionality, or it may lead to functional weakening. Therefore, how to scientifically and rationally combine new functional components to achieve better effects of enhancing immunity and relieving visual fatigue is still a problem to be solved in this field. Summary of the invention

[0005] In order to solve the problem of lack of scientific and reasonable compatibility between new functional components that can improve the efficacy of the composition, the present invention provides a functional composition and its application in enhancing immunity and relieving visual fatigue.

[0006] The technical solution of the present invention:

[0007] A functional composition comprises the following components in parts by weight: 57.1-97.8 parts of bovine colostrum powder, 0.83-17.7 parts of blueberry juice powder, 0.33-15.6 parts of blueberry anthocyanin, 0.33-13.6 parts of chrysanthemum powder and 0.33-13.6 parts of wolfberry powder.

[0008] Furthermore, the invention comprises the following components in parts by weight: 69.7-95.3 parts of bovine colostrum powder, 1.7-10.9 parts of blueberry juice powder, 0.95-10.8 parts of blueberry anthocyanin, 0.75-7.4 parts of chrysanthemum powder and 0.75-7.4 parts of wolfberry powder.

[0009] Furthermore, the invention comprises the following components in parts by weight: 81.1-91.3 parts of bovine colostrum powder, 2.7-5.8 parts of blueberry juice powder, 2.1-5.7 parts of blueberry anthocyanin, 1.8-4.3 parts of chrysanthemum powder and 1.8-4.3 parts of wolfberry powder.

[0010] Furthermore, the composition includes the following components in parts by weight: 90.4 parts of bovine colostrum powder, 3.1 parts of blueberry juice powder, 2.3 parts of blueberry anthocyanin, 2.1 parts of wolfberry powder and 2.1 parts of chrysanthemum powder.

[0011] The components of the functional composition provided by the present invention can better enhance immunity and relieve visual fatigue by cooperating with each other, wherein the immunoglobulins and other antibacterial factors (lactoferrin, osteopontin, lactoperoxidase, lysozyme, antimicrobial peptides, etc.) in bovine colostrum can work together to remove pathogens. It can be used as a natural nutritional source for enhancing immune function. Igs in bovine colostrum mainly include IgG, IgM, IgA and IgD, and high levels of Igs can not only provide passive immunity for the body, but also regulate the adaptive and innate immune systems. The immunoregulatory function of bovine colostrum Igs is not limited to calves, and it also has a clearing effect on pathogens of other mammals such as humans. Bovine colostrum IgG can reach the intestine intact and exert antibacterial and immunoregulatory functions. Bovine colostrum is rich in various nutrients such as neurotrophic growth factor, brain peptides, lysine, taurine, etc., which helps to enhance memory, promote retinal development, and improve vision.

[0012] Blueberry anthocyanins contain 15 complete anthocyanin components, which can reduce the oxidative damage of light to retinal cells, strengthen the elasticity of eye microvessels, promote blood circulation, and maintain normal eye pressure. It is a functional component that truly protects the eyes. Blueberry anthocyanins can not only protect the eyes, but also improve the body's immune function. Anthocyanins can activate the immune system, protect serum immunoglobulins from free radicals, activate macrophages, and enhance human immunity. Blueberry anthocyanins can improve the immunoregulatory activity of lymphocytes by promoting the proliferation of spleen lymphocytes and the secretion of cytokines IL-6 and TNF-α; by promoting the phagocytic function of macrophages and the secretion of cytokines IL-12 and reducing the secretion of IL-4, it can improve the immunoregulatory activity of macrophages, thereby improving the body's immune function.

[0013] Blueberries have the functions of enhancing and regulating human immunity, promoting and activating the resynthesis of rhodopsin in the retina, relieving eye fatigue, dryness, swelling, pain, photophobia, etc., protecting the eyes from light damage, delaying the aging process of the eyes, reducing blurred vision, preventing the occurrence of diseases, increasing macular pigment density, promoting the development of the macula, and enhancing near vision, protecting and improving human vision.

[0014] Chrysanthemum has the effect of clearing the liver and improving eyesight, and is used to treat red, swollen and painful eyes, blurred vision, etc. Chrysanthemum polysaccharides also have immunomodulatory functions, regulating the levels of tumor necrosis factor TNF-α and gamma-interferon (IFN), increasing the thymus index and spleen index, enhancing the phagocytic activity of macrophages, and accelerating the removal rate of carbon particles in the blood.

[0015] Lycium barbarum has a strong antioxidant capacity, which not only protects eye nerve cells, but also blood vessels. Lycium barbarum polysaccharides can reduce the degeneration and oxidative stress of photoreceptor cells, improve vision, and reduce the number of apoptosis of retinal ganglion cells without affecting intraocular pressure. Many studies have also shown that Lycium barbarum polysaccharides have the effects of promoting immunity, anti-tumor, and scavenging free radicals.

[0016] Blueberries, chrysanthemums, and wolfberries contain antioxidant ingredients that can enhance the activity of immune cells, improve the body's immunity, and provide a solid immune barrier for the eyes. A strong immune system is an important line of defense for the human body against the invasion of external pathogens. By regulating immune function, the body's resistance to eye diseases is enhanced and the risk of eye infections is reduced. At the same time, good immune function can also promote the repair and regeneration of eye tissues and accelerate the recovery process of eye diseases.

[0017] The invention also provides application of the functional composition in food or health care products.

[0018] Furthermore, the food is a formula milk powder, a formula milk, a solid beverage, a liquid beverage, a ready-to-eat mixed food or a baked food.

[0019] Furthermore, the health care product is in the form of powder, granules, tablets, pills, capsules or oral liquid.

[0020] Furthermore, the effective intake of the functional composition is 1.152 g / day.

[0021] Beneficial effects of the present invention:

[0022] The present invention uses bovine colostrum powder, blueberry juice powder, blueberry anthocyanin, chrysanthemum powder and wolfberry powder as natural active functional components, and fully exerts the synergistic effect of each functional component in enhancing immunity and relieving visual fatigue through scientific and reasonable compatibility, and develops a natural, safe, healthy and effective functional composition that helps to enhance matrix immunity and relieve visual fatigue.

[0023] The functional composition provided by the present invention is particularly suitable for people with low immunity and those with easily fatigued eyes. Since low immunity of the human body can also cause eye discomfort, low immunity may lead to reduced tear secretion, dry eye surface, conjunctivitis, keratitis and other eye symptoms, and the functional composition provided by the present invention can improve immunity while better preventing eye discomfort, and has very important application value.

[0024] The functional composition provided by the present invention is applied to food or health care products, which can greatly improve the snack status of medicine and food in food and health care products, and at the same time has the characteristics of being easy to carry and easy to eat. DETAILED DESCRIPTION

[0025] The technical solution of the present invention is further described below in conjunction with the embodiments, but it is not limited thereto. Any modification or equivalent replacement of the technical solution of the present invention without departing from the spirit and scope of the technical solution of the present invention shall be included in the protection scope of the present invention. The process equipment or devices not specifically noted in the following embodiments are all conventional equipment or devices in the art. If not specifically specified, the raw materials used in the embodiments of the present invention can be obtained commercially; if not specifically specified, the technical means used in the embodiments of the present invention are all conventional means well known to those skilled in the art.

[0026] Example 1

[0027] This embodiment provides a functional composition, which is composed of the following components in parts by weight: 90.4 parts of bovine colostrum powder, 3.1 parts of blueberry juice powder, 2.3 parts of blueberry anthocyanins, 2.1 parts of wolfberry powder and 2.1 parts of chrysanthemum powder.

[0028] In this embodiment, the bovine colostrum powder is a powder product made from the bovine colostrum within 24 hours after the birth of a healthy dairy cow, which is sterilized, centrifuged and defatted, and low-temperature / freeze-dried; the blueberry juice powder is a powder product made from fresh blueberries squeezed and low-temperature dried; the blueberry anthocyanin is made from blueberry fruits as raw materials, and is made into a powder product through processes such as enzymolysis, water extraction, purification, concentration, and drying, and the purity is not less than 40%; the wolfberry powder and the chrysanthemum powder are respectively made by grinding and drying wolfberries and chrysanthemums.

[0029] Example 2

[0030] This embodiment provides a functional composition, which is composed of the following components in parts by weight: 95.3 parts of bovine colostrum powder, 1.7 parts of blueberry juice powder, 0.95 parts of blueberry anthocyanins, 0.75 parts of wolfberry powder and 1.3 parts of chrysanthemum powder.

[0031] Example 3

[0032] This embodiment provides a functional composition, which is composed of the following components in parts by weight: 81.1 parts of bovine colostrum powder, 5.8 parts of blueberry juice powder, 5.7 parts of blueberry anthocyanins, 3.1 parts of wolfberry powder and 4.3 parts of chrysanthemum powder.

[0033] Example 4

[0034] This embodiment provides a functional composition, which is composed of the following components in parts by weight: 97.8 parts of bovine colostrum powder, 0.83 parts of blueberry juice powder, 0.52 parts of blueberry anthocyanins, 0.52 parts of wolfberry powder and 0.33 parts of chrysanthemum powder.

[0035] Example 5

[0036] This embodiment provides a functional composition, which is composed of the following components in parts by weight: 69.7 parts of bovine colostrum powder, 10.9 parts of blueberry juice powder, 10.8 parts of blueberry anthocyanins, 5.3 parts of wolfberry powder and 3.3 parts of chrysanthemum powder.

[0037] Comparative Example 1

[0038] This comparative example provides a composition, which is composed of the following components in parts by weight: 95.8 parts of blueberry juice powder, 2.1 parts of wolfberry and 2.1 parts of chrysanthemum powder.

[0039] Comparative Example 2

[0040] This comparative example provides a composition, which consists of the following components in parts by weight: 95.6 parts of blueberry juice powder, 2.3 parts of blueberry anthocyanins and 2.1 parts of chrysanthemum powder.

[0041] Comparative Example 3

[0042] This comparative example provides a composition, which consists of the following components in parts by weight: 95.6 parts of blueberry juice powder, 2.3 parts of blueberry anthocyanins and 2.1 parts of wolfberry powder.

[0043] Test Example 1

[0044] This test example investigated the immunity-enhancing function of the functional composition of the present invention. The functional composition sample provided in Example 1 was mixed into feed by the multiple dilution method and given to mice to conduct a test on the immunity-enhancing function of the functional composition.

[0045] 1. This experiment is to compare the feeding effects of Example 1, Comparative Example 1, Comparative Example 2, and Comparative Example 3 when feeding mice; wherein, the functional composition of Example 1 was fed to mice at three addition amounts: low, medium, and high, and mice were fed with distilled water as a control group.

[0046] 2. Experimental materials: 280 healthy female mice weighing 18-22g were selected and randomly divided into 5 immunization groups, each of which was further divided into 7 subgroups, with 8 mice in each subgroup. The experimental period was 30 days. The carbon clearance test and animal organ / body ratio were determined in the first immunization group, the half hemolysis value (HC50) was determined in the second immunization group, and the antibody-producing cell detection was detected, the delayed-type hypersensitivity reaction test was conducted in the third immunization group, the mouse peritoneal macrophage phagocytosis chicken red blood cell test was conducted in the fourth immunization group, and the ConA-induced mouse spleen lymphocyte transformation test and NK cell activity determination were conducted in the fifth immunization group.

[0047] The functional composition of Example 1 is divided into three dosage groups of low, medium and high according to 5, 10 and 30 times of the daily intake (19.2 mg / kg BW) (i.e. 96, 192 and 576 mg / kg BW). Comparative Examples 1 to 3 are calculated separately, and the daily intake of Comparative Examples 1 to 3 is 192 mg / kg BW, 192 mg / kg BW and 192 mg / kg BW respectively.

[0048] 3. Test results

[0049] (I) The effects on the body weight of mice in each group after being fed with the functional composition of Example 1 and Comparative Examples 1-3 for 30 days are shown in Tables 1-5 respectively.

[0050] Table 1: Effect of the functional composition on the body weight of mice (immunized group)

[0051]

[0052] Table 2: Effects of the functional composition on the body weight of mice (immunization group 2)

[0053]

[0054] Table 3: Effects of the functional composition on the body weight of mice (three immunized groups)

[0055]

[0056] Table 4: Effects of the functional composition on the body weight of mice (four immunized groups)

[0057]

[0058] Table 5: Effect of the functional composition on the body weight of mice (five immunization groups)

[0059]

[0060] As can be seen from the results in Tables 1 to 5, there was no significant difference in the initial and final body weights of the animals in the low, medium and high doses of each immunization test group and in comparative examples 1-3 compared with those in the control group (P>0.05), indicating that under the experimental conditions, the functional composition and comparative examples 1-3 had no effect on the weight gain of mice.

[0061] (II) The effects on the organ / body weight ratio of each group of mice after being fed with the functional composition of Example 1 and Comparative Examples 1-3 for 30 days are shown in Table 6.

[0062] Table 6: Effects of the functional composition on the organ / body weight ratio of mice

[0063]

[0064] As can be seen from Table 6, when mice were orally fed with different doses of the functional composition of Example 1 for 30 days, there was no significant difference in the spleen / body weight ratio and thymus / body weight ratio between the low, medium, and high dose groups, comparative examples 1-3 and the control group (P>0.05), indicating that under the experimental conditions, the functional composition of Example 1 and comparative examples 1-3 had no effect on the organ / body weight ratio of mice.

[0065] (III) The effects of the functional composition of Example 1 and the samples of Comparative Examples 1-3 on delayed-type hypersensitivity (DTH) of each group of mice after administration for 30 days are shown in Table 7.

[0066] Table 7: Effects of the functional composition on delayed-type hypersensitivity (DTH) in mice

[0067]

[0068]

[0069] Note: * Compared with the control group, there is a significant difference P<0.05, ** Compared with the control group, there is a very significant difference P<0.01; □ Compared with comparative example 1, there is a significant difference P<0.05. □□ Compared with comparative example 1, there is a very significant difference P<0.01; # Compared with comparative example 2, there is a significant difference P<0.05. ## Compared with comparative example 2, there is a very significant difference P<0.01; △ Compared with comparative example 3, there is a significant difference P<0.05. △△ Compared with comparative example 3, there is a very significant difference (P<0.01).

[0070] As shown in Table 7, mice were orally given different doses of the functional composition and comparative examples 1-3 samples for 30 days. After statistical processing, the difference in the swelling degree of the foot (thickening of the foot) before and after the injection of SRBC was statistically significant (P<0.05) and extremely significant (P<0.01) between the low, medium and high dose groups and the control group, and there was no significant difference (P>0.05) between the comparative examples 1-3 groups and the control group. The low dose group was significantly different from comparative example 1 (P<0.05), and the medium and high dose groups were significantly different from comparative examples 2 and 3 and extremely significant (P<0.01). It shows that the functional composition can enhance delayed allergic reactions in mice.

[0071] (IV) The effects of the functional composition and the samples of comparative examples 1-3 on the transformation of spleen lymphocytes in each group of mice 30 days after administration are shown in Table 8.

[0072] Table 8: Effects of the functional composition on transformation of mouse spleen lymphocytes

[0073]

[0074] As can be seen from Table 8, different doses of the functional composition and comparative examples 1-3 samples were orally administered to mice for 30 days. After statistical processing, there was no significant difference in the transformation function of the spleen lymphocytes of mice in each dosage group compared with the control group (P>0.05), indicating that the functional composition and comparative examples 1-3 could not enhance the transformation function of the spleen lymphocytes of mice.

[0075] (V) The effects of the functional composition and the samples of comparative examples 1-3 on the half hemolytic value (HC50) of mice in each group after administration for 30 days are shown in Table 9.

[0076] Table 9: Effect of the functional composition on the half hemolytic value (HC) of mice 50 )

[0077]

[0078] Note: ** Compared with the control group, there was a very significant difference (P<0.01); □□ Compared with comparative example 1, there is a very significant difference P<0.01; ## Compared with comparative example 2, there is a very significant difference P<0.01; △△ Compared with comparative example 3, there is a very significant difference (P<0.01).

[0079] As shown in Table 9, after different doses of the functional composition and samples of comparative examples 1-3 were orally administered to mice for 30 days, the HC50 values ​​of the medium and high dose groups were significantly different from those of the control group and comparative examples 1-3 (P<0.01), while there was no significant difference between the low dose group and comparative examples 1-3 and the control group (P>0.05), indicating that the functional composition can increase the HC50 value of mice.

[0080] (VI) The effects of different doses of the functional composition and samples of comparative examples 1-3 on mouse antibody-producing cells after 30 days of administration to each group of mice are shown in Table 10.

[0081] Table 10: Effects of the functional composition on mouse antibody-producing cells

[0082]

[0083] As can be seen from Table 10, when different doses of the functional composition and comparative examples 1-3 samples were orally administered to mice for 30 days, there was no significant difference in the number of plaques between each dose group and the comparative example group compared with the control group (P>0.05), indicating that the functional composition could not enhance the function of mouse antibody-producing cells.

[0084] (VII) The effects of different doses of the functional composition and samples of comparative examples 1-3 on the carbon clearance ability of mice in each group after 30 days of administration are shown in Table 11.

[0085] Table 11: Effects of functional composition on carbon clearance function of mice

[0086]

[0087] As can be seen from Table 11, different doses of the functional composition and comparative samples 1-3 were orally administered to mice for 30 days. After statistical processing, there was no significant difference in the phagocytic index between the dose groups and the comparative group and the control group (P>0.05), indicating that the functional composition could not increase the carbon clearance function of mice.

[0088] (VIII) The effects of different doses of the functional composition and samples of Comparative Examples 1-3 on the phagocytosis of chicken red blood cells by mouse peritoneal macrophages 30 days after administration of each group of mice are shown in Table 12.

[0089] Table 12: Effect of the functional composition on the phagocytosis of chicken red blood cells by mouse macrophages

[0090]

[0091] Note: * There was a significant difference compared with the control group (P<0.05). ** Compared with the control group, there was a very significant difference (P<0.01); □ Compared with comparative example 1, there is a significant difference P<0.05. □□ Compared with comparative example 1, there is a very significant difference P<0.01; # Compared with comparative example 2, there is a significant difference P<0.05. ## Compared with comparative example 2, there is a very significant difference P<0.01; △ Compared with comparative example 3, there is a significant difference P<0.05. △△ Compared with comparative example 3, there is a very significant difference (P<0.01).

[0092] As shown in Table 12, different doses of the functional composition and samples of comparative examples 1-3 were orally administered to mice for 30 days. After statistical processing, the phagocytosis rates of the four groups were subjected to a variance homogeneity test. If the variances were not homogeneous, variable transformation was performed. Where P is the phagocytic rate, expressed as a decimal. The four groups of comparison results are after the original data are transformed and the variance is equal. The phagocytic index of the low, medium and high dose groups is significantly different from that of the control group (P<0.05) and extremely significantly different (P<0.01), and the phagocytic index of the comparison group is not significantly different from that of the control group (P>0.05). There is a significant difference between the low dose group and comparison example 1 (P<0.05), and there is a significant difference and extremely significant difference (P<0.01) between the medium and high dose groups and comparison examples 2 and 3. It shows that the functional composition can enhance the phagocytic function of mouse peritoneal macrophages.

[0093] (IX) The effects of the functional composition and samples of comparative examples 1-3 on the NK cell activity of each group of mice after administration for 30 days are shown in Table 13.

[0094] Table 13: Effects of the functional composition on mouse NK cell activity

[0095]

[0096] As shown in Table 13, different doses of the functional composition and samples of Comparative Examples 1-3 were orally administered to mice for 30 days, and the NK cell activity was changed by variable transformation. Wherein P is NK cell activity, expressed as a decimal. After statistical processing, there was no significant difference in NK cell activity between each dosage group and the comparative group and the control group (P>0.05), indicating that the functional composition had no effect on the activity function of mouse NK cells.

[0097] 4. Test conclusion

[0098] Different doses of the functional composition of Example 1 were orally administered to mice for 30 days. The results showed that the functional composition of Example 1 in the low, high and medium dose groups could significantly enhance the delayed-type hypersensitivity of mice, increase the half hemolysis value (HC 50) of mice and enhance the phagocytic function of peritoneal macrophages. According to the criteria in the "Health Food Function Test and Evaluation Method (2023 Edition)", it is believed that the functional composition of Example 1 has the function of helping to enhance immunity.

[0099] It can be seen from the above test results that the functional composition prepared by the present invention has the function of helping to enhance immunity under the synergistic effect of various components.

[0100] Test Example 2

[0101] This test example investigates the function of the functional composition of the present invention in relieving visual fatigue, and a human test on relieving visual fatigue is conducted using a functional chewable tablet containing the functional composition Example 1.

[0102] 1. This test is conducted on 45 adults aged 18 to 65 who use their eyes for a long time and whose eyesight is easily fatigued.

[0103] 2. Test materials: The test period is 60 days. The method of consumption is once a day, 2 tablets each time, and 1.152 g of the functional composition is consumed daily.

[0104] 3. Test items

[0105] The effective rate of symptom improvement, average symptom score, visual acuity improvement and visual persistence were measured.

[0106] 4. Test results

[0107] The effects of the functional composition of Example 1 on visual fatigue of consumers are shown in Tables 14 to 17 respectively.

[0108] Table 14: Effects of functional chewable tablets on eye symptoms of subjects

[0109] symptom Number of cases Number of Improved Cases Effectiveness / % Eye swelling 17 16 88.24 Eye pain 20 19 90.00 photophobia 13 12 84.62 Blurred vision 14 13 92.86 Dry eyes 24 22 91.67 Foreign body sensation 21 19 90.48 Tears 25 22 92.00 General discomfort associated with visual fatigue 18 17 94.44

[0110] As can be seen from Table 14, after the subjects consumed the functional chewable tablets for 60 days, the symptoms of visual fatigue such as eye swelling, eye pain, photophobia, blurred vision, dry eyes, foreign body sensation, tearing, and general discomfort were significantly improved, with an effective rate of ≥84.62%, which was significantly different from before the trial (P < 0.01).

[0111] Table 15: Symptom average score results

[0112] Number of cases Before tasting After tasting 45 2.91±2.17 0.91±0.89

[0113] As shown in Table 15, after the subjects consumed the functional chewable tablets for 60 days, the average symptom score decreased significantly compared with before consumption (P < 0.01).

[0114] Table 16: Visual persistence before and after the functional chewable tablets trial

[0115] Before tasting After tasting Increase 0.63±0.10 0.76±0.12 0.13±0.10

[0116] As shown in Table 16, after the subjects consumed the functional chewable tablets for 60 days, the subjects' visual persistence increased significantly compared with that before the trial (P < 0.01).

[0117] Table 17: Visual acuity improvement

[0118]

[0119] As shown in Table 17, after the subjects consumed the functional chewable tablets for 60 days, the visual acuity of both eyes improved compared with that before the trial, and the visual acuity of both eyes of the subjects increased extremely significantly (P < 0.01).

[0120] 5. Test conclusion

[0121] After the subjects took the functional chewable tablets for 60 days, their visual fatigue symptoms were significantly improved, with an effective rate of more than 84.62%. The average symptom score decreased significantly, the visual persistence increased by 0.13, and their vision was also significantly improved.

[0122] It can be seen from the consumption results of the above-mentioned groups of people that the functional composition prepared by the present invention has the function of alleviating visual fatigue under the synergistic effect of various components.

[0123] Although the present invention has been described in detail above with general descriptions and specific embodiments, it is obvious to those skilled in the art that some modifications or improvements may be made thereto based on the present invention. Therefore, these modifications or improvements made without departing from the principles and spirit of the present invention all fall within the scope of protection claimed by the present invention.

Claims

1. A functional composition, characterized in that: The invention comprises the following components in parts by weight: 57.1-97.8 parts of bovine colostrum powder, 0.83-17.7 parts of blueberry juice powder, 0.33-15.6 parts of blueberry anthocyanin, 0.33-13.6 parts of chrysanthemum powder and 0.33-13.6 parts of wolfberry powder.

2. A functional composition according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 69.7-95.3 parts of bovine colostrum powder, 1.7-10.9 parts of blueberry juice powder, 0.95-10.8 parts of blueberry anthocyanin, 0.75-7.4 parts of chrysanthemum powder and 0.75-7.4 parts of wolfberry powder.

3. A functional composition according to claim 2, characterized in that: The invention comprises the following components in parts by weight: 81.1-91.3 parts of bovine colostrum powder, 2.7-5.8 parts of blueberry juice powder, 2.1-5.7 parts of blueberry anthocyanin, 1.8-4.3 parts of chrysanthemum powder and 1.8-4.3 parts of wolfberry powder.

4. A functional composition according to claim 3, characterized in that: The invention comprises the following components in parts by weight: 90.4 parts of bovine colostrum powder, 3.1 parts of blueberry juice powder, 2.3 parts of blueberry anthocyanin, 2.1 parts of wolfberry powder and 2.1 parts of chrysanthemum powder.

5. Use of the functional composition according to any one of claims 1 to 4 in food or health products.

6. Use of the functional composition according to claim 5 in food or health products, characterized in that: The food is a formula milk powder, a formula milk, a solid beverage, a liquid beverage, a ready-to-eat mixed food or a baked food.

7. Use of the functional composition according to claim 6 in food or health products, characterized in that: The dosage form of the health care product is powder, granule, tablet, pill, capsule or oral liquid.

8. Use of the functional composition according to claim 7 in food or health products, characterized in that: The effective intake of the functional composition is 1.152 g / day.

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