Spinal cord disconnector for animal experiment

By designing a spinal cord separator for animal experiments, using the mechanism of adjusting thread columns and compression springs, the error problem in the spinal cord separator in the prior art is solved, and the accuracy and reliability of the experiment are improved.

CN119587205AInactive Publication Date: 2025-03-11安徽理工大学第一附属医院(淮南市第一人民医院)
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Patent Information

Application Number
CN202411696246.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-25
Publication Date
2025-03-11
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

The lack of special tools in the spinal cord dissociation model in the prior art leads to errors in the dissociation process, affecting the accuracy and reliability of the research.

Method used

An animal experimental spinal cord separator was designed, using two identical scissors to set side by side. By adjusting the coordination between the threaded column and the compression spring, the distance between the scissor heads is adjusted to ensure the accuracy and quality of spinal cord separator separation.

Benefits of technology

Through this spinal cord separator, it can significantly reduce artificial errors, improve the degree of standardization of the experiment, and ensure that multiple sets of consistent lengths or different spinal cord samples are obtained to meet different research needs.

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Abstract

The invention belongs to the technical field of experimental instruments, and discloses an animal experiment spinal cord dissecting device which comprises two same scissors which are arranged side by side, a scissor shaft of one of the scissors is fixedly connected with an adjusting threaded column, the adjusting threaded column penetrates through a scissor shaft of the other scissor, and the scissor shaft of the other scissor is fixedly connected with the adjusting threaded column. The scissors are connected with the adjusting threaded column in a sliding mode, the adjusting threaded column is sleeved with a compression spring, the compression spring is located between the two scissors, the outer side end of the adjusting threaded column is in threaded connection with an adjusting nut, and the distance between the scissors can be accurately adjusted and fixed. According to the spinal cord dissecting device, required accuracy and quality can be achieved during spinal cord dissecting, personal errors are reduced, and the standardization degree of an experiment is improved.
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Description

Technical Field

[0001] The invention belongs to the technical field of experimental instruments, and in particular relates to a spinal cord disconnector for animal experiments. Background Art

[0002] The spinal cord disconnection model is an important basis for neural regeneration research experiments. It plays a key role in understanding the regeneration mechanism after spinal cord injury and developing new treatment strategies. The key technical point of the spinal cord disconnection model lies in the disconnection distance, which is usually measured in millimeters. Therefore, there are precise and homogeneous requirements for the accuracy and quality of disconnection. At present, there are disputes about the disconnection distance and accuracy. Due to the lack of special tools, there may be errors in the disconnection process, which affects the accuracy and reliability of the research. The patent of this invention aims to provide a spinal cord disconnector with high precision and stable quality for the study of spinal cord disconnection models to improve the accuracy and repeatability of the experiment. Summary of the invention

[0003] In view of the deficiencies of the prior art, the object of the present invention is to provide a spinal cord disconnector for animal experiments, which can ensure that the required accuracy and quality can be achieved when performing spinal cord disconnection, reduce human errors, and improve the standardization of experiments.

[0004] The purpose of the present invention can be achieved through the following technical solutions:

[0005] A spinal cord disconnector for animal experiments comprises two identical scissors, which are arranged side by side. The shear shaft of one of the scissors is fixedly connected with an adjusting threaded column, which passes through the shear shaft of the other pair of scissors, so that the scissors are slidably connected with the adjusting threaded column. A compression spring is sleeved on the adjusting threaded column, and the compression spring is located between the two scissors. The outer end of the adjusting threaded column is threadedly connected with an adjusting nut.

[0006] The above technical solution, its principle and technical effect:

[0007] Since the compression spring is always in a compressed state, the elastic force of the compression spring makes the two scissors tend to move in opposite directions. By rotating the adjustment nut to screw in or out along the adjustment thread column, and then cooperating with the elastic force of the compression spring, the distance between the scissor heads of the two scissors can be adjusted. When in use, the spinal cord of the experimental subject is placed horizontally on the scissor heads of the two scissors, and the two scissors are driven to jointly sever the spinal cord. When the distance between the two scissors is kept unchanged, the spinal cord is severed to obtain multiple groups of spinal cord samples with the same length. The spinal cord can also be severed after adjusting the distance between the two scissors to obtain multiple groups of spinal cord samples with different lengths.

[0008] In a preferred example, the present invention can be further configured as follows: a pair of scissors includes two scissor heads, one of which is provided with a first concave arc-shaped blade, and the other is provided with a second concave arc-shaped blade, and the first arc-shaped blade and the second arc-shaped blade are arranged correspondingly.

[0009] In a preferred example, the present invention can be further configured as follows: the depth of the first arc-shaped blade is greater than the depth of the second arc-shaped blade, and the maximum width of the first arc-shaped blade is not greater than the maximum width of the second arc-shaped blade.

[0010] In a preferred example, the present invention can be further configured as follows: the first arc-shaped blade and the scissors tips form an arc-shaped hook structure.

[0011] In a preferred example, the present invention can be further configured as follows: at least one limiting rod is fixedly connected to the side of the handle of one pair of the scissors, and the limiting rod passes through the handle of the other pair of the scissors, so that the handle of the scissors is slidably connected to the limiting rod.

[0012] In a preferred example, the present invention can be further configured as follows: the outer side surface of the adjusting nut is rotatably connected to a limiting ring, the limiting ring is sleeved on the adjusting threaded column, a gap is left between the limiting ring and the adjusting threaded column, and a fastening bolt is connected to the limiting ring along its radial thread.

[0013] In a preferred example, the present invention can be further configured as follows: two grooves are provided on the circumferential side of the adjusting threaded column along its length, and the fastening bolt is located in one of the grooves.

[0014] In a preferred example, the present invention can be further configured as follows: the interior of another of the grooves is engraved with scale lines along its length.

[0015] In a preferred example, the present invention can be further configured as follows: the diameter of the compression spring decreases gradually from the middle to both ends.

[0016] The nouns, conjunctions or adjectives involved in the above technical solution are explained as follows:

[0017] Fixed connection refers to a connection in which parts or components are fixed without any relative movement. There are two types of connection: detachable and non-detachable.

[0018] (1) A removable connection is a connection that uses screws, splines, wedge pins, etc. to hold parts together. This type of connection can be disassembled for maintenance without damaging the parts. However, the specifications of the connectors used must be correct (such as the length of the bolts, keys, and wedge pins) and they must be properly tightened.

[0019] (2) Non-detachable connections mainly refer to welding, riveting and tenoning. Since they need to be disassembled by forging, sawing or oxygen cutting for maintenance or replacement, spare parts generally cannot be reused. At the same time, when making connections, attention should be paid to process quality, technical inspection and remedial measures (such as calibration, polishing, etc.).

[0020] A threaded connection refers to a detachable connection in which the connected parts are connected together using threaded parts (or the threaded parts of the connected parts).

[0021] A sliding connection is when two objects are in contact but not fixed and can slide relative to each other.

[0022] A rotational connection is a connection between parts that allows the parts to rotate relative to each other.

[0023] Beneficial effects of the present invention:

[0024] 1. The spinal cord disconnector of the present invention ensures that the required accuracy and quality can be achieved when performing spinal cord disconnection, reduces human errors, and improves the standardization of experiments.

[0025] 2. Place the subject's spinal cord horizontally on the scissor heads of two pairs of scissors, and drive the two scissors to sever the spinal cord at the same time. While keeping the distance between the two scissors unchanged, the spinal cord is severed to obtain multiple groups of spinal cord samples of the same length. Alternatively, the distance between the two scissors can be adjusted and the spinal cord is severed to obtain multiple groups of spinal cord samples of different lengths.

[0026] 3. The tip of the scissors is hook-shaped, which can easily hook up the spinal cord. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, for ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0028] Figure 1 It is a side view schematic diagram of the overall structure of an embodiment of the present invention;

[0029] Figure 2 It is another side view schematic diagram of the overall structure of an embodiment of the present invention;

[0030] Figure 3 is a schematic plan view of a pair of scissors according to an embodiment of the present invention;

[0031] Figure 4 It is a partial structural schematic diagram of the adjusting threaded column of an embodiment of the present invention. DETAILED DESCRIPTION

[0032] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0033] In the description of the present invention, it should be understood that the terms "opening", "upper", "lower", "thickness", "top", "middle", "length", "inside", "all around" and the like indicating orientation or positional relationship are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the components or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the present invention.

[0034] like Figures 1 to 4 As shown, an animal experimental spinal cord disconnector comprises two identical scissors 1, which are arranged side by side. The shear shaft 2 of one of the scissors 1 is fixedly connected with an adjusting threaded column 3, and the adjusting threaded column 3 passes through the shear shaft 2 of the other scissors 1, so that the scissors 1 are slidably connected with the adjusting threaded column 3, and a compression spring 4 is sleeved on the adjusting threaded column 3, and the compression spring 4 is located between the two scissors 1. The outer end of the adjusting threaded column 3 is threadedly connected with an adjusting nut 5.

[0035] Since the compression spring 4 is always in a compressed state, the elastic force of the compression spring 4 makes the two scissors 1 have a tendency to move in opposite directions. By rotating the adjustment nut 5 and screwing it in or out along the adjustment threaded column 3, and then cooperating with the elastic force of the compression spring 4, the distance between the scissor heads 6 of the two scissors 1 can be adjusted. When in use, the spinal cord of the experimental subject is placed horizontally on the scissor heads 6 of the two scissors 1, and the two scissors 1 are driven to perform a spinal cord severing operation together. When the distance between the two scissors 1 is kept unchanged, the spinal cord is severed to obtain multiple groups of spinal cord samples with the same length. The spinal cord can also be severed after adjusting the distance between the two scissors 1 to obtain multiple groups of spinal cord samples with different lengths.

[0036] In one embodiment of the present invention, a pair of scissors 1 includes two scissor heads 6, one of which is provided with a first arc-shaped blade 7 and the other is provided with a second arc-shaped blade 8, and the first arc-shaped blade 7 and the second arc-shaped blade 8 are arranged correspondingly. When the spinal cord needs to be severed, the spinal cord can be placed between the first arc-shaped blade 7 and the second arc-shaped blade 8 on the two scissors 1. When the two scissor heads 6 are closed to each other, the space enclosed by the first arc-shaped blade 7 and the second arc-shaped blade 8 gradually decreases until the final closure, and the spinal cord is cut. Such a design prevents the spinal cord from moving horizontally and detaching during shearing.

[0037] In one embodiment of the present invention, the depth of the first arc-shaped blade 7 is greater than the depth of the second arc-shaped blade 8, and the maximum width of the first arc-shaped blade 7 is not greater than the maximum width of the second arc-shaped blade 8. Such a design allows the spinal cord to be positioned at the first arc-shaped blade 7, thereby preventing the spinal cord from moving horizontally and detaching during shearing.

[0038] In one embodiment of the present invention, the first arc-shaped blade 7 and the scissors tip 9 form an arc-shaped hook structure. This design facilitates the insertion of the scissors tip 9 of the scissors 1 into the body of the experimental subject to hook up the spinal cord, making it easier for the spinal cord to enter the first arc-shaped blade 7.

[0039] In one embodiment of the present invention, at least one limiting rod 11 is fixedly connected to the side of the handle 10 of one pair of scissors 1, and the limiting rod 11 passes through the handle 10 of another pair of scissors 1, so that the handle 10 of the scissors 1 is slidably connected to the limiting rod 11. Such a design, on the one hand, does not hinder the distance adjustment between the two pairs of scissors 1, and on the other hand, enables the two pairs of scissors 1 to perform the spinal cord cutting operation simultaneously and synchronously.

[0040] In one embodiment of the present invention, the outer side of the adjusting nut 5 is rotatably connected to a limiting ring 12, which is sleeved on the adjusting threaded column 3, with a gap between the limiting ring 12 and the adjusting threaded column 3, and a fastening bolt 13 is threadedly connected along the radial direction of the limiting ring 12. In order to reduce the rotation of the adjusting nut 5 and affect the length of the spinal cord sample, the fastening bolt 13 is tightened so that the fastening bolt 13 is tightly against the adjusting threaded column 3, thereby limiting the lateral movement of the adjusting nut 5.

[0041] In one embodiment of the present invention, two grooves 14 are provided along the length of the peripheral side of the adjusting threaded column 3, and the fastening bolt 13 is located in one of the grooves 14. With such a design, when the fastening bolt 13 is tightened, the thread on the surface of the adjusting threaded column 3 will not be damaged.

[0042] In one embodiment of the present invention, the inside of another groove 14 is engraved with scale lines along its length. The distance between the two scissors 1 can be more intuitively understood. The length of the spinal cord experimental sample of the present application often needs to be 2mm to 10mm, so when designing the scale lines of the present application, the minimum unit can be designed to be less than or equal to 1mm. The total length is not less than 10mm.

[0043] In one embodiment of the present invention, the diameter of the compression spring 4 decreases from the middle to both ends. When the compression spring 4 is compressed to the shortest length, the part with a small diameter shrinks into the part with a large diameter. Compared with the cylindrical spring, the compression spring 4 in the present application has a smaller thickness after being compressed, so that the minimum distance between the two scissors 1 can be smaller. For example, using the compression spring 4 in the present application, when the compression spring 4 is compressed to the shortest length, the shortest length is 2mm, then the distance adjustment range between the two scissors 1 in the present application is 2mm-10mm, then the corresponding length of the severable spinal cord is 2mm-10mm, if the same diameter spring wire and the same number of turns of the cylindrical spring are used, when the cylindrical spring is compressed to the shortest length, the shortest length is greater than 2mm, such as 4mm, then the distance adjustment range between the two scissors 1 is 4mm-10mm, then the corresponding length of the severable spinal cord is 4mm-10mm.

[0044] In the description of this specification, the description with reference to the terms "one embodiment", "example", "specific example", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0045] The above shows and describes the basic principles, main features and advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited by the above embodiments, and the above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, and these changes and improvements all fall within the scope of the present invention to be protected.

Claims

1. A spinal cord disconnector for animal experiments, comprising two identical scissors (1), the two scissors (1) being arranged side by side, characterized in that: The shear shaft (2) of one of the scissors (1) is fixedly connected to an adjusting threaded column (3), and the adjusting threaded column (3) passes through the shear shaft (2) of the other pair of scissors (1), so that the scissors (1) and the adjusting threaded column (3) are slidably connected, and a compression spring (4) is sleeved on the adjusting threaded column (3), and the compression spring (4) is located between the two scissors (1), and the outer end of the adjusting threaded column (3) is threadedly connected to an adjusting nut (5).

2. The animal experimental spinal cord disconnector according to claim 1, characterized in that: A pair of scissors (1) comprises two scissor heads (6), one of the scissor heads (6) is provided with a first inwardly concave arc-shaped blade edge (7), and the other of the scissor heads (6) is provided with a second inwardly concave arc-shaped blade edge (8), and the first arc-shaped blade edge (7) and the second arc-shaped blade edge (8) are arranged correspondingly.

3. The animal experimental spinal cord disconnector according to claim 2, characterized in that: The depth of the first arc-shaped blade (7) is greater than the depth of the second arc-shaped blade (8), and the maximum width of the first arc-shaped blade (7) is not greater than the maximum width of the second arc-shaped blade (8).

4. The animal experimental spinal cord disconnector according to claim 2, characterized in that: The first arc-shaped blade (7) and the scissor tips (9) of the scissors (1) form an arc-shaped hook structure.

5. The animal experimental spinal cord disconnector according to claim 1, characterized in that: At least one limiting rod (11) is fixedly connected to the side of the handle (10) of one of the scissors (1), and the limiting rod (11) passes through the handle (10) of the other pair of the scissors (1), so that the handle (10) of the scissors (1) is slidably connected to the limiting rod (11).

6. The animal experimental spinal cord disconnector according to claim 1, characterized in that: The outer side surface of the adjusting nut (5) is rotatably connected to a limiting ring (12), and the limiting ring (12) is sleeved on the adjusting threaded column (3). A gap is left between the limiting ring (12) and the adjusting threaded column (3), and a fastening bolt (13) is threadedly connected to the limiting ring (12) along its radial direction.

7. The animal experimental spinal cord disconnector according to claim 6, characterized in that: Two grooves (14) are provided on the circumferential side of the adjusting threaded column (3) along its length, and the fastening bolt (13) is located in one of the grooves (14).

8. The animal experimental spinal cord disconnector according to claim 7, characterized in that: The interior of the other groove (14) is engraved with scale lines along its length.

9. The animal experimental spinal cord disconnector according to claim 1, characterized in that: The diameter of the compression spring (4) decreases gradually from the middle to both ends.