Traditional Chinese medicine formula for treating rheumatoid arthritis and preparation method of external tincture

Abstract

The invention discloses a traditional Chinese medicine formula for treating rheumatoid arthritis and a preparation method of an external tincture. The traditional Chinese medicine composition is mainly prepared from radix aconiti agrestis, radix aconiti, rhizoma sparganii, honeysuckle stem, caulis spatholobi, cortex periplocae, safflower, semen brassicae, myrrh, frankincense, arisaema cum bile, uncaria, radix saposhnikoviae, cassia twig, clove, asarum, costus root, angelica sinensis, radix paeoniae rubra, radix clematidis, ardisia crenata, caulis sinomenii, gaultheria yunnanensis, lycopodium clavatum, asiatic toddalia root, dipsacus asper, camphor and menthol. The traditional Chinese medicine formula is adopted and matched with the method to prepare the external tincture, the traditional Chinese medicine formula is prepared according to a traditional Chinese medicine theory scientific formula, has the effects of dispelling wind and removing dampness, promoting blood circulation to remove blood stasis and stimulating menstrual flow to relieve pain, can effectively treat rheumatoid arthritis, does not generate drug-resistant toxic and side effects, and is worthy of popularization and application.

Description

Technical Field

[0001] The invention relates to the technology of traditional Chinese medicine field, in particular to a traditional Chinese medicine formula for treating rheumatoid arthritis and a preparation method of an external tincture. Background Art

[0002] With the acceleration of the pace of life and the increase of work pressure, the number of patients with rheumatoid arthritis is increasing, and the market demand for rheumatoid arthritis drugs is huge. The main cause of rheumatism is that the occurrence of rheumatoid arthritis is closely related to infection. Streptococcal infection is considered to be a common factor inducing rheumatoid arthritis. Some people are prone to rheumatoid arthritis due to genetic factors. The cold and humid external environment is conducive to the reproduction of bacteria and is an important factor in the onset and recurrence of rheumatoid arthritis. However, autoimmune dysfunction, blood in a hypercoagulable state, and endocrine factors may also be related to the onset of rheumatoid arthritis. Rheumatoid arthritis is a migratory, multiple arthritis, mainly involving large joints such as the neck, shoulder, waist, knee, ankle, elbow, and wrist. There may be redness, swelling, heat, pain, and tenderness locally, which may be accompanied by exudation but no suppuration. Joint pain usually occurs or worsens when the climate becomes cold or rainy. There is no residual deformation after the attack, but it often recurs. The joints are painful and swollen for a long time, and the flexion and extension are not good, resulting in stiffness and deformation, and even effusion in the joints. Mild and atypical cases may involve a single joint or a few joints, or involve some uncommon joints, such as the hip joint, finger joint, mandibular joint, sternoclavicular joint, sternocostal joint, and frontal joint. The latter is often mistaken for a symptom of cardiac inflammation. The incidence rate is often related to the living standard. Overcrowded housing, poor nutrition, and lack of medicine are conducive to the reproduction and spread of streptococci, which often lead to the prevalence of this disease.

[0003] At present, rheumatism is mainly treated with Western medicine, which has no significant effect and may cause drug resistance and side effects. Traditional Chinese medicine believes that when rheumatism becomes a disease, one must not rush for results, but only use wind-dispelling and dampness-removing drugs and blood-activating and stasis-removing drugs for treatment, and use reasonable drug treatment; the wind-dispelling and dampness-removing drugs and blood-activating and stasis-removing drugs commonly used in traditional Chinese medicine include Panax notoginseng, Chuanxiong, Millettia reticulata, peach kernel, Angelica dahurica, Gentiana macrophylla, Chuanwu, and Aconite. Therefore, the development of rheumatism preparations with traditional Chinese medicine characteristics can not only enrich patients' medication options, but also give play to the advantages of traditional Chinese medicine and Chinese medicine, and has broad market prospects. Summary of the invention

[0004] In view of this, the present invention aims at the deficiencies in the prior art, and its main purpose is to provide a Chinese medicine formula for treating rheumatoid arthritis and a method for preparing an external tincture, which can effectively solve the problem that the existing rheumatism treatment methods using Western medicines have insignificant efficacy and can also produce drug resistance and toxic side effects.

[0005] To achieve the above purpose, the present invention adopts the following technical solutions:

[0006] A Chinese medicine formula for treating rheumatoid arthritis, comprising the following raw materials in parts by weight: 50-100 parts of Chuanwu, 50-100 parts of Caowu, 30-60 parts of Tripterygium wilfordii, 40-80 parts of Lonicera japonica, 60-120 parts of Millettia spatholobi, 30-60 parts of Perennial Cortex, 30-60 parts of Carthamus tinctorius, 30-60 parts of Sinapis alba, 30-60 parts of Myrrh, 30-60 parts of Frankincense, 40-80 parts of Arisaema ciliata, 40-80 parts of Uncaria rhynchophylla, 40-80 parts of Saposhnikovia divaricata, 40-80 parts of cassia twig, 40-80 parts of cloves, 40-80 parts of asarum, 30-60 parts of magnolia officinalis, 30-60 parts of angelica sinensis, 30-60 parts of red peony root, 40-80 parts of clematis, 80-160 parts of cyperus rotundus, 80-160 parts of caulis spatholobi, 90-180 parts of radix pelargonidis, 80-160 parts of herba schizonepetae, 80-160 parts of palmatum frutescens, 80-160 parts of dipsera, 80-160 parts of camphor, and 60-120 parts of menthol.

[0007] Preferably, the following raw materials are included in parts by weight: 50 parts of Chuanwu, 50 parts of Kusnezoffii, 30 parts of Tripterygium wilfordii, 40 parts of Honeysuckle Caulis, 60 parts of Millettia spatholobi, 30 parts of Perennial Cortex, 30 parts of Carthamus tinctorius, 30 parts of White Mustard Seed, 30 parts of Myrrh, 30 parts of Frankincense, 40 parts of Arisaema cinerea, 40 parts of Uncaria rhynchophylla, 40 parts of Saposhnikovia divaricata, 40 parts of Cassia twig, 40 parts of Clove, 40 parts of Asarum, 30 parts of Magnolia officinalis, 30 parts of Angelica sinensis, 30 parts of Red Peony Root, 40 parts of Clematis, 80 parts of Nine-clawed Dragon, 80 parts of Caulis Sinomenii, 90 parts of Pennisetum radix, 80 parts of Lycopodiella cernua, 80 parts of Palmatum oxyphylla, 80 parts of Dipsacus asper, 80 parts of Camphor, and 60 parts of Menthol.

[0008] Preferably, the aconite, chuanwu, trillium, honeysuckle, millettia, cortex perillae, safflower, white mustard, myrrh, frankincense, arisaema, Uncaria, siler, cassia twig, clove, asarum, costusroot, angelica, red peony root, clematis, nine-clawed dragon, green wind vine, radix poriae, herba spatholobi, herba spatholobi, camphor and menthol are all Chinese herbal medicine slices.

[0009] A method for preparing an external tincture comprises the following steps: using the aforementioned Chinese medicine formula for treating rheumatoid arthritis, grinding the above raw materials into fine powder to form Chinese medicine powder, then soaking the Chinese medicine powder in ethanol, and then performing a distillation extraction process, adding Chinese medicinal materials such as nine-clawed dragon, green wind vine, bone-penetrating ball, stretch tendon grass, blood-sealing palm, and Sichuan teasel to the extracted liquid, soaking for 72 hours, filtering to remove residues, and then adding camphor and menthol, waiting for them to dissolve, and filtering to obtain an external tincture.

[0010] Compared with the prior art, the present invention has obvious advantages and beneficial effects. Specifically, it can be seen from the above technical solution that:

[0011] The external tincture is prepared by adopting the Chinese medicine formula of the present invention and using the method of the present invention. The Chinese medicine formula of the present invention is scientifically formulated according to traditional Chinese medicine theory, has the effects of dispelling wind and dampness, promoting blood circulation and removing blood stasis, and promoting menstruation and relieving pain, can effectively treat rheumatoid arthritis, will not produce drug resistance and toxic side effects, and is worthy of popularization and use. DETAILED DESCRIPTION

[0012] The invention discloses a Chinese medicine formula for treating rheumatoid arthritis, which comprises the following raw materials in parts by weight: 50-100 parts of Chuanwu, 50-100 parts of Caowu, 30-60 parts of Tripterygium wilfordii, 40-80 parts of Lonicera japonica, 60-120 parts of Millettia spatholobi, 30-60 parts of Perennial Cortex, 30-60 parts of Carthamus tinctorius, 30-60 parts of Sinapis alba, 30-60 parts of Myrrh, 30-60 parts of Frankincense, 40-80 parts of Arisaema cinerea, 40-80 parts of Uncaria rhynchophylla, and 40-80 parts of Saposhnikovia divaricata. 0 parts, 40-80 parts of cassia twigs, 40-80 parts of cloves, 40-80 parts of asarum, 30-60 parts of magnolia officinalis, 30-60 parts of angelica sinensis, 30-60 parts of red peony root, 40-80 parts of clematis, 80-160 parts of nine-clawed dragon, 80-160 parts of green wind vine, 90-180 parts of radix pentaphyllum, 80-160 parts of striata herba, 80-160 parts of blood-sealing palm, 80-160 parts of dipsera, 80-160 parts of camphor, and 60-120 parts of menthol. The aforementioned aconite, chuanwu, trillium, honeysuckle vine, millettia reticulata, cortex angelicae, safflower, white mustard, myrrh, frankincense, arisaema, Uncaria rhynchophylla, siler, cassia twig, clove, asarum, costusroot, angelica sinensis, red peony root, clematis, nine-clawed dragon, cereus, radix poriae, herba spatholobi, herba spatholobi, cactus, camphor and menthol are all Chinese medicinal pieces.

[0013] The invention also discloses a method for preparing an external tincture, which comprises the following steps: using the aforementioned Chinese medicine formula for treating rheumatoid arthritis, grinding the raw materials into fine powder to form Chinese medicine powder, then soaking the Chinese medicine powder in ethanol, and then performing a distillation extraction process, adding Chinese medicines such as Rhizoma Corydalis, Caulis Spatholobi, Herba Lycopodii, Caulis Polygoni Multiflori, etc. to the extracted liquid, soaking for 72 hours, filtering to remove residues, adding camphor and menthol, and filtering after dissolving to obtain an external tincture.

[0014] The present invention is further described in detail with multiple embodiments below:

[0015] Embodiment 1:

[0016] The present embodiment discloses a Chinese medicine formula for treating rheumatoid arthritis, comprising the following raw materials in parts by weight: 50 parts of Chuanwu, 50 parts of Kusnezoffii, 30 parts of Tripterygium wilfordii, 40 parts of Honeysuckle, 60 parts of Millettia spatholobi, 30 parts of Perennial Cortex, 30 parts of Carthamus tinctorius, 30 parts of White Mustard Seed, 30 parts of Myrrh, 30 parts of Frankincense, 40 parts of Arisaema cinerea, 40 parts of Uncaria rhynchophylla, 40 parts of Saposhnikovia divaricata, 40 parts of Cinnamomum cassia, 40 parts of Clove, 40 parts of Asarum, 30 parts of Magnolia officinalis, 30 parts of Angelica sinensis, 30 parts of Red Peony Root, 40 parts of Clematidis, 80 parts of Nine-clawed Dragon, 80 parts of Caulis Sinomenii, 90 parts of Perfume Ball, 80 parts of Lycopodiella cernua, 80 parts of Palmatum oxyphylla, 80 parts of Dipsacus asper, 80 parts of Camphor, and 60 parts of Menthol. The aforementioned aconite, chuanwu, trillium, honeysuckle vine, millettia reticulata, cortex angelicae, safflower, white mustard, myrrh, frankincense, arisaema, Uncaria rhynchophylla, siler, cassia twig, clove, asarum, costusroot, angelica sinensis, red peony root, clematis, nine-clawed dragon, cereus, radix poriae, herba spatholobi, herba spatholobi, cactus, camphor and menthol are all Chinese medicinal pieces.

[0017] The present embodiment also discloses a method for preparing an external tincture, which comprises the following steps: using the aforementioned Chinese medicine formula for treating rheumatoid arthritis, grinding the above raw materials into fine powder to form Chinese medicine powder, then soaking the Chinese medicine powder in ethanol, and then performing a distillation extraction process, adding Chinese medicinal materials such as Rhizoma Corydalis, Caulis Spatholobi, Herba Lycopodii, Herba Dipsaci, and Radix Dipsaci to the extracted liquid, soaking for 72 hours, filtering to remove residues, and adding camphor and menthol, waiting for them to dissolve, and filtering to obtain an external tincture.

[0018] Embodiment 2:

[0019] The present embodiment discloses an external tincture for treating rheumatoid arthritis, comprising the following raw materials in parts by weight: 100 parts of Chuanwu, 100 parts of Kusnezoffii, 60 parts of Tripterygium wilfordii, 80 parts of Lonicera japonica, 120 parts of Millettia spatholobi, 60 parts of Perennial Cortex, 60 parts of Carthamus tinctorius, 60 parts of White Mustard Seed, 60 parts of Myrrh, 60 parts of Frankincense, 80 parts of Arisaema cinerea, 80 parts of Uncaria rhynchophylla, 80 parts of Saposhnikovia divaricata, 80 parts of Cinnamomum cassia, 80 parts of Clove, 80 parts of Asarum, 60 parts of Aucklandia lappa, 60 parts of Angelica sinensis, 60 parts of Red Peony Root, 80 parts of Clematidis, 160 parts of Achyranthes bidentata, 160 parts of Caulis Sinomenii, 180 parts of Perilla frutescens, 160 parts of Herba Lycopodii, 160 parts of Palmatum oxyphylla, 160 parts of Dipsacus asper, 160 parts of Camphor, and 120 parts of menthol. The aforementioned aconite, chuanwu, trillium, honeysuckle vine, millettia reticulata, cortex angelicae, safflower, white mustard, myrrh, frankincense, arisaema, Uncaria rhynchophylla, siler, cassia twig, clove, asarum, costusroot, angelica sinensis, red peony root, clematis, nine-clawed dragon, cereus, radix poriae, herba spatholobi, herba spatholobi, cactus, camphor and menthol are all Chinese medicinal pieces.

[0020] The present embodiment also discloses a method for preparing an external tincture, which comprises the following steps: using the aforementioned Chinese medicine formula for treating rheumatoid arthritis, grinding the above raw materials into fine powder to form Chinese medicine powder, then soaking the Chinese medicine powder in ethanol, and then performing a distillation extraction process, adding Chinese medicinal materials such as Rhizoma Corydalis, Caulis Spatholobi, Herba Lycopodii, Herba Dipsaci, and Radix Dipsaci to the extracted liquid, soaking for 72 hours, filtering to remove residues, and adding camphor and menthol, waiting for them to dissolve, and filtering to obtain an external tincture.

[0021] Embodiment 3:

[0022] The present embodiment discloses a traditional Chinese medicine formula for treating rheumatoid arthritis, comprising the following raw materials in parts by weight: 75 parts of Chuanwu, 75 parts of Kusnezoffii, 45 parts of Tripterygium wilfordii, 60 parts of Honeysuckle Caulis, 90 parts of Millettia spatholobi, 45 parts of Perennial Cortex, 45 parts of Carthamus tinctorius, 45 parts of White Mustard Seed, 45 parts of Myrrh, 45 parts of Frankincense, 60 parts of Arisaema cinerea, 60 parts of Uncaria rhynchophylla, 60 parts of Saposhnikovia divaricata, 60 parts of Cinnamomum cassia, 60 parts of Clove, 60 parts of Asarum, 45 parts of Magnolia officinalis, 45 parts of Angelica sinensis, 45 parts of Red Peony Root, 60 parts of Clematidis, 120 parts of Achyranthes bidentata, 120 parts of Caulis Sinomenii, 130 parts of Perilla frutescens, 120 parts of Herba Lycopodii, 120 parts of Palmatum oxyphylla, 120 parts of Dipsacus asper, 120 parts of Camphor, and 90 parts of Menthol. The aforementioned aconite, chuanwu, trillium, honeysuckle vine, millettia reticulata, cortex angelicae, safflower, white mustard, myrrh, frankincense, arisaema, Uncaria rhynchophylla, siler, cassia twig, clove, asarum, costusroot, angelica sinensis, red peony root, clematis, nine-clawed dragon, cereus, radix poriae, herba spatholobi, herba spatholobi, cactus, camphor and menthol are all Chinese medicinal pieces.

[0023] The present embodiment also discloses a method for preparing an external tincture, which comprises the following steps: using the aforementioned Chinese medicine formula for treating rheumatoid arthritis, grinding the above raw materials into fine powder to form Chinese medicine powder, then soaking the Chinese medicine powder in ethanol, and then performing a distillation extraction process, adding Chinese medicinal materials such as Rhizoma Corydalis, Caulis Spatholobi, Herba Lycopodii, Herba Dipsaci, and Radix Dipsaci to the extracted liquid, soaking for 72 hours, filtering to remove residues, and adding camphor and menthol, waiting for them to dissolve, and filtering to obtain an external tincture.

[0024] After use tests, the external tinctures prepared from the Chinese medicine formulas in the above embodiments are all scientifically formulated according to traditional Chinese medicine theory, have the effects of dispelling wind and dampness, promoting blood circulation and removing blood stasis, and relieving pain, and can effectively treat rheumatoid arthritis, among which Example 3 has the best therapeutic effect.

[0025] The technical principle of the present invention is described above in conjunction with specific embodiments. These descriptions are only for explaining the principle of the present invention and cannot be interpreted as limiting the scope of protection of the present invention in any way. Based on the explanations herein, those skilled in the art can associate other specific implementations of the present invention without paying creative labor, and these methods will fall within the scope of protection of the present invention.

Claims

1. A Chinese medicine formula for treating rheumatoid arthritis, characterized in that: The invention comprises the following raw materials in parts by weight: 50-100 parts of Chuanwu, 50-100 parts of Caowu, 30-60 parts of Tripterygium wilfordii, 40-80 parts of Lonicera japonica, 60-120 parts of Millettia spatholobi, 30-60 parts of Perennial Cortex, 30-60 parts of Carthamus tinctorius, 30-60 parts of White Mustard Seed, 30-60 parts of Myrrh, 30-60 parts of Frankincense, 40-80 parts of Arisaema cinerea, 40-80 parts of Uncaria rhynchophylla, 40-80 parts of Saposhnikovia divaricata, and 40-80 parts of Cinnamomum cassia. , 40-80 parts of cloves, 40-80 parts of asarum, 30-60 parts of magnolia officinalis, 30-60 parts of angelica, 30-60 parts of red peony root, 40-80 parts of clematis, 80-160 parts of nine-clawed dragon, 80-160 parts of green wind vine, 90-180 parts of radix pentaphyllum, 80-160 parts of striata herba, 80-160 parts of blood-sealing palm, 80-160 parts of dipsera, 80-160 parts of camphor, and 60-120 parts of menthol.

2. A Chinese medicine formula for treating rheumatoid arthritis as claimed in claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 50 parts of Chuanwu, 50 parts of Kusnezoffii, 30 parts of Tripterygium wilfordii, 40 parts of Honeysuckle vine, 60 parts of Millettia spatholobi, 30 parts of Perennial Cortex, 30 parts of Carthamus tinctorius, 30 parts of White Mustard Seed, 30 parts of Myrrh, 30 parts of Frankincense, 40 parts of Arisaema cinerea, 40 parts of Uncaria rhynchophylla, 40 parts of Saposhnikovia divaricata, 40 parts of Cinnamomum cassia, 40 parts of Clove, 40 parts of Asarum, 30 parts of Magnolia officinalis, 30 parts of Angelica sinensis, 30 parts of Red Peony Root, 40 parts of Clematis chinensis, 80 parts of Nine-clawed Dragon, 80 parts of Caulis Sinomenii, 90 parts of Pennisetum radix, 80 parts of Lycopodiella cernua, 80 parts of Palmatum oxyphylla, 80 parts of Dipsacus asper, 80 parts of Camphor and 60 parts of Menthol.

3. A Chinese medicine formula for treating rheumatoid arthritis as claimed in claim 1, characterized in that: The aforementioned aconite, chuanwu, trillium, honeysuckle vine, millettia reticulata, cortex angelicae, safflower, white mustard, myrrh, frankincense, arisaema, Uncaria rhynchophylla, siler, cassia twig, clove, asarum, costusroot, angelica sinensis, red peony root, clematis, nine-clawed dragon, cereus, radix poriae, herba spatholobi, herba spatholobi, cactus, camphor and menthol are all Chinese medicinal pieces.

4. A method for preparing an external tincture, characterized in that: A Chinese medicine formula for treating rheumatoid arthritis as described in any one of claims 1 to 3 is used, the above raw materials are ground into fine powder to form Chinese medicine powder, then the Chinese medicine powder is soaked in ethanol, and then subjected to a distillation extraction process, the extracted liquid is soaked in Chinese medicinal materials such as nine-clawed dragon, green wind vine, bone-penetrating ball, stretch tendon grass, blood-sealing palm, and Sichuan teasel for 72 hours, filtered to remove the residue, and camphor and menthol are added. After they are dissolved, they are filtered to obtain an external tincture.