Radio frequency ablation capsule

Abstract

The invention provides a radiofrequency ablation capsule, which can adjust the distribution of ablation electrodes around a focus so as to carry out multiple ablation, is convenient to operate and ensures the ablation effectiveness. The device comprises a permanent magnet shell and an ablation electrode, the periphery of a suspension is rotationally arranged on the permanent magnet shell, and an inner gear ring is arranged on the lower portion of the suspension; an ablation electrode and a pcb (printed circuit board) are arranged on a sliding table below the suspension; a motor shaft of a motor fixed at the lower end of the permanent magnet shell penetrates through a sleeve and fixes a sun gear; a planetary gear carrier is fixed at the upper end of the sleeve; a planetary gear is simultaneously meshed with the sun gear and the inner gear ring; the ablation electrode penetrates through the suspension; the lower part of the periphery of the sleeve is a spiral section matched with the spiral hole in the sliding table, and the upper part of the periphery of the sleeve is a smooth section; the motor shaft rotates in a certain direction, the ablation electrode moves upwards relative to the suspension while the ablation electrode rotates forwards relative to the permanent magnet shell, and the ablation electrode stops moving upwards, the motor shaft continues to rotate in a certain direction, and the ablation electrode continues to rotate forwards relative to the permanent magnet shell until the sliding table is separated from the spiral section.

Description

Technical Field

[0001] This patent relates to a radiofrequency therapeutic device with ablation and cutting functions in medicine, specifically a radiofrequency ablation capsule. Background Art

[0002] Radiofrequency ablation technology is a minimally invasive treatment method, which is widely used clinically because of its small trauma and good effect. It mainly relies on radiofrequency therapy devices with ablation and cutting functions, and the treatment mechanism is mainly thermal effect. When radiofrequency current flows through human tissue, the rapid change of the electromagnetic field causes the polarized water molecules in the tissue to move at high speed, generating heat (i.e., endogenous thermal effect), causing coagulative necrosis of the tissue at the lesion site, thereby achieving the purpose of treatment.

[0003] When a common radiofrequency ablation capsule with an ablation electrode enters the human body and contacts the lesion, the contact pressure between the ablation electrode and the lesion is often difficult to accurately define, and the operating doctor needs to make judgments based on experience, which is relatively random. In addition, after the ablation electrode contacts the lesion, only part of the lesion can be ablated. If the ablation electrode can rotate, it can fully contact different parts of the lesion and ablate the lesion tissue multiple times, which is more convenient to operate and has better ablation treatment effects, and can also reduce the patient's pain.

[0004] But existing radiofrequency ablation capsules cannot achieve this. Summary of the invention

[0005] This patent provides a radiofrequency ablation capsule, which can adjust the distribution of ablation electrodes around the lesion to perform multiple ablations. It is easy to operate, ensures the effectiveness of ablation, and alleviates the patient's pain. At the same time, its structure is ingenious, compact, and small in size.

[0006] In order to achieve the above technical objectives, the technical solution adopted by this patent is:

[0007] A radiofrequency ablation capsule comprises a permanent magnet shell, an ablation electrode electrically connected to a PCB board, a suspension outer periphery rotatably arranged on the inner periphery of the upper end of the permanent magnet shell, and an inner gear ring is arranged at the lower part of the suspension; the lower end of the ablation electrode and the PCB board are arranged on a slide table which can move up and down in the permanent magnet shell, the slide table is located below the suspension, and a motor fixed to the lower end of the permanent magnet shell is arranged below the slide table; the motor shaft passes upward through a sleeve fixed to the permanent magnet shell and extending upward, and a sun gear is fixed to the top end of the motor shaft; a planetary gear frame is fixed to the upper end of the sleeve, and the planetary gears rotatably arranged on the planetary gear frame are meshed with the sun gear and the inner gear ring at the same time; the upper part of the ablation electrode passes through a guide hole opened on the suspension; the sleeve passes through a spiral hole opened on the slide table, the lower part of the outer periphery of the sleeve is a spiral section with a spiral line matching the spiral hole, and the upper part of the outer periphery of the sleeve is a smooth section with a diameter smaller than the spiral hole;

[0008] The motor is working, the motor shaft rotates in a certain direction, and the sun gear drives the inner ring gear, suspension, slide, and ablation electrode to rotate in the positive direction relative to the permanent magnet housing and sleeve through the planetary gear. At the same time, the slide and ablation electrode move upward relative to the sleeve and suspension until the slide moves upward to the smooth section of the sleeve and the slide is separated from the cooperation with the spiral section. Then, the slide and ablation electrode stop moving upward. At this time, the motor shaft continues to rotate in a certain direction, and the inner ring gear, suspension, slide, and ablation electrode continue to rotate in the positive direction relative to the permanent magnet housing and sleeve.

[0009] The motor shaft rotates in a direction opposite to a certain direction. The sun gear drives the inner ring gear, suspension, slide, and ablation electrode to rotate in the opposite direction relative to the permanent magnet housing and sleeve through the planetary gear. At the same time, the slide cooperates with the spiral section of the sleeve, and the slide and ablation electrode move downward relative to the sleeve and suspension.

[0010] As a further improvement to the above-mentioned radiofrequency ablation capsule, the upper end of the suspension is provided with an LED light for lighting and an optical sensor for photographing.

[0011] As a further improvement to the above-mentioned radio frequency ablation capsule, the upper part of the stacked flexible circuit board is electrically connected to the PCB board, and the LED lamp and the optical sensor are electrically connected to the upper part of the stacked flexible circuit board.

[0012] As a further improvement to the above-mentioned radio frequency ablation capsule, a receiving groove for receiving the stacked flexible circuit board is provided at the bottom of the suspension.

[0013] As a further improvement to the above-mentioned radiofrequency ablation capsule, the cable passes through the lower end of the permanent magnet housing and is electrically connected to a socket connected to the lower part of the PCB board.

[0014] As a further improvement to the above-mentioned radiofrequency ablation capsule, there are two ablation electrodes, which are symmetrically arranged with the axis of the motor shaft as the center.

[0015] As a further improvement of the above-mentioned radiofrequency ablation capsule, the ablation electrode includes an electrode sleeve fixed on a slide, extending up and down, and passing through a guide hole, an electrode slidably set in the electrode sleeve, and a pressure sensor is set between the lower end of the electrode and the lower part of the electrode sleeve.

[0016] As a further improvement to the above radio frequency ablation capsule, it also includes an elastic material arranged between the pressure sensor and the lower end of the electrode sleeve.

[0017] As a further improvement to the above radiofrequency ablation capsule, it also includes a processor, the motor is a stepper motor, and the optical sensor, the pressure sensor, and the stepper motor controller are electrically connected to the processor and work under the control of the processor.

[0018] The beneficial effects of this patent are:

[0019] The motor is working, the motor shaft rotates in a certain direction (assuming it is counterclockwise), and the sun gear drives the inner gear ring, suspension, slide, and ablation electrode to rotate in the positive direction relative to the permanent magnet housing and sleeve through the planetary gear (assuming it is clockwise). At the same time, when the slide and the spiral section of the sleeve are matched, the slide and the ablation electrode move upward relative to the sleeve and the suspension until the slide moves upward to the smooth section of the sleeve and the slide is separated from the matching with the spiral section. The slide and the ablation electrode stop moving upward, and the upper end of the ablation electrode completely extends out of the suspension. At this time, the motor shaft continues to rotate counterclockwise, and the inner gear ring, suspension, slide, and ablation electrode continue to rotate clockwise relative to the permanent magnet housing and sleeve; the purpose of rotating the ablation electrode and placing it at different positions around the lesion can be achieved. Then move the entire radiofrequency ablation capsule so that the ablation electrode can be in contact with the lesion and then ablation treatment can be performed.

[0020] The motor shaft rotates clockwise, and the sun gear drives the inner ring gear, suspension, slide, and ablation electrode to rotate counterclockwise relative to the permanent magnet housing and sleeve through the planetary gear. At the same time, the slide cooperates with the spiral section of the sleeve, and the slide and ablation electrode move downward relative to the sleeve and suspension.

[0021] Optical sensors such as CMOS sensors can take pictures of lesions, etc., which is convenient for operators to observe in real time. LED lights can illuminate lesions, etc., which is more conducive to observation and taking pictures.

[0022] The stacked flexible circuit board can be stacked or unfolded according to the distance between the suspension and the slide, realizing the transmission of electrical signals between the PCB board and the LED lights and optical sensors.

[0023] The pressure sensor can detect the pressure between the ablation electrode and the lesion, and the operator can move the radiofrequency ablation capsule more accurately based on the value of the pressure sensor.

[0024] The motor drives the suspension to rotate at a reduced speed through the planetary gear mechanism, and the slide table and the sleeve are matched with a spiral, which can effectively reduce the lifting speed of the slide table and prevent the ablation electrode from suddenly extending and causing accidental damage to human organs. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 Schematic diagram of the main view of the radiofrequency ablation capsule (ablation electrode retracted).

[0026] Figure 2 Schematic diagram of the main view of the radiofrequency ablation capsule (ablation electrode extended).

[0027] Figure 3 Schematic diagram of the side view of the radiofrequency ablation capsule (ablation electrode retracted).

[0028] Figure 4Schematic diagram of the side view of the radiofrequency ablation capsule (ablation electrode extended).

[0029] Figure 5 , 6 , 7 and 8 are the front view, bottom view, top view and side view of the suspension, etc. respectively.

[0030] Fig. 9 , 10 1 and 11 are respectively the front view, bottom view and top view of the sleeve, planetary gear mechanism, etc.

[0031] Fig.12 , 13 They are the front view and top view of the slide, ablation electrode, PCB board, etc.

[0032] Fig.14 This is a block diagram of the electrical connection principle of the radiofrequency ablation capsule.

[0033] Fig.15 This is a flowchart of radiofrequency ablation operation.

[0034] Fig.16 This is the workflow diagram of the radiofrequency ablation capsule.

[0035] Fig.17 It is a flowchart of the ablation electrode extension instruction processing.

[0036] Fig.18 It is a flow chart of the processing of the suspension rotation instruction after the ablation electrode is extended.

[0037] In the figure, suspension 1, bearing 2, permanent magnet housing 3, cover 5, optical sensor 6, LED lamp 7, guide hole 8, inner ring gear 9, accommodating groove 10, stacked flexible circuit board 11, slide 12, spiral hole 121, ablation electrode 13, electrode sleeve 131, electrode 132, pressure sensor 133, elastic material 134, PCB board 14, motor 15; motor shaft 151, sleeve 16, spiral section 161, smooth section 162, sun gear 17, planetary gear carrier 18, planetary gear 19, cable 20, socket 21, FPC socket 22. DETAILED DESCRIPTION

[0038] The specific implementation of this patent is further described below according to the accompanying drawings:

[0039] See also Figure 1-4 In the radiofrequency ablation capsule shown, the outer periphery of the suspension 1 is slidably arranged on the inner periphery of the upper end of the permanent magnet housing 3 through the bearing 2.

[0040] A cover 5 is provided at the center of the upper end of the suspension 1, and an optical sensor (such as CMOS) 6 for shooting is arranged in the cover 5. Two symmetrical LED lights 7 for lighting are arranged at the upper edge of the suspension 1, and two symmetrical guide holes 8 are provided. An inner gear ring 9 is fixed at the center of the bottom of the suspension 1. A receiving groove 10 capable of accommodating a laminated flexible circuit board 11 after lamination is provided at the bottom of the suspension 1 outside the inner gear ring 9.

[0041] The lower part of the stacked flexible circuit board 11 is electrically connected to the PCB board through the FPC socket 22 , the upper end of the stacked flexible circuit board is located in the receiving groove 10 , and the LED lamp 7 and the optical sensor 6 are electrically connected to the upper part of the stacked flexible circuit board 11 .

[0042] Two ablation electrodes 13 are symmetrically arranged on the slide table 12 with the axis of the motor shaft as the center.

[0043] The ablation electrode 13 includes an electrode sleeve 131 fixed on the slide, extending up and down, and passing through the guide hole, an electrode 132 slidably arranged in the electrode sleeve, and a pressure sensor 133 and an elastic material 134 are arranged in sequence between the lower end of the electrode and the lower part of the electrode sleeve. The upper part of the ablation electrode 13 passes through the guide hole 8 opened on the suspension.

[0044] A pcb board 14 is fixed at the bottom of a slide 12 that can move up and down in a permanent magnet housing. The slide is located below the suspension. A motor 15 is fixed to the lower end of the permanent magnet housing. The motor shaft 151 passes upward through a sleeve 16 that is fixed to the permanent magnet housing and extends upward, and a sun gear 17 is fixed to the top of the motor shaft. A planetary gear carrier 18 is fixed to the upper end of the sleeve, and two planetary gears 19 that are rotated and arranged on the planetary gear carrier are simultaneously engaged with the sun gear 17 and the inner gear ring 9. The sleeve 16 passes through the spiral hole 121 opened in the center of the slide 12 and the pcb board 14. The lower part of the outer periphery of the sleeve 16 is a spiral section 161 with a spiral line that matches the spiral hole, and the upper part of the outer periphery of the sleeve is a smooth section 162 with a diameter smaller than the spiral hole.

[0045] The cable 20 passes through the lower end of the permanent magnet housing and is electrically connected to a socket 21 connected to the lower part of the PCB board 14. The motor 15 is a stepping motor.

[0046] The PCB 14 is connected to a processor, and the optical sensor and the pressure sensor communicate with the processor. The LED lamp, the stepper motor controller, etc. work under the control of the processor. See the overall block diagram Fig.14 .

[0047] The motor is working, the motor shaft rotates counterclockwise, and the sun gear drives the inner gear ring, suspension, slide, and ablation electrode to rotate clockwise relative to the permanent magnet housing and sleeve through the planetary gear. At the same time, when the slide and the spiral section of the sleeve are matched, the slide and the ablation electrode move upward relative to the sleeve and the suspension until the slide moves upward to the smooth section of the sleeve and the slide is separated from the spiral section. The slide and the ablation electrode stop moving upward, and the upper end of the ablation electrode completely extends out of the suspension. At this time, the motor shaft continues to rotate counterclockwise, and the inner gear ring, suspension, slide, and ablation electrode continue to rotate clockwise relative to the permanent magnet housing and sleeve, so as to achieve the purpose of rotating the ablation electrode and placing it at different positions around the lesion. Then move the entire radiofrequency ablation capsule so that the ablation electrode can be in contact with the lesion for ablation treatment.

[0048] The motor shaft rotates clockwise, and the sun gear drives the inner ring gear, suspension, slide, and ablation electrode to rotate counterclockwise relative to the permanent magnet housing and sleeve through the planetary gear. At the same time, the slide cooperates with the spiral section of the sleeve, and the slide and ablation electrode move downward relative to the sleeve and suspension.

[0049] When the slide rises to the non-threaded section (smooth section) of the sleeve, the clockwise rotation of the slide around the sleeve will not cause the slide to rise, and the counterclockwise rotation of the slide at this position will cause the slide to fall.

[0050] The following is a detailed description of the specific operation process of ablation treatment of gastric lesions. Fig.15 .

[0051] a. The patient swallows the radiofrequency ablation capsule until it reaches the stomach;

[0052] b. The radiofrequency ablation capsule is powered on; the dynamic image acquired by the optical sensor is transmitted back through the cable;

[0053] c. Under the guidance of the image, the capsule is driven by an external magnetic field to move to the vicinity of the lesion and hover;

[0054] d. Send the ablation electrode extension command through the cable, so that the motor shaft of the stepper motor rotates counterclockwise, and the stepper motor stops rotating after the RF ablation capsule is fully extended to the ablation electrode (see Fig.17 );

[0055] e. Fine-tune the position of the radiofrequency ablation capsule through external magnetic field control so that the lesion is in the center of the image;

[0056] f. Send a rotation command to the RF ablation capsule, and the ablation electrode, suspension, etc. rotate together until the ablation electrode rotates to the required ablation angle (see Fig.18 );

[0057] g. Adjust the external magnetic field so that the radiofrequency ablation capsule can reliably contact the lesion. During the process of adjusting the external magnetic field, the data of the two pressure sensors are continuously read to determine whether the pressure of the two ablation electrodes on the lesion reaches the expected threshold value; if the pressure reaches the expected threshold value, the adjustment of the external magnetic field ends; if the pressure does not reach the expected threshold value, the external magnetic field continues to be adjusted;

[0058] h. After the external magnetic field adjustment is completed, turn on the radiofrequency therapy device to perform radiofrequency ablation treatment;

[0059] i. Then observe the lesion morphology and evaluate whether ablation is needed again. If ablation is not needed again, send the ablation electrode retraction command through the cable, so that the motor shaft of the stepper motor rotates clockwise, and the stepper motor stops rotating after the RF ablation capsule is completely retracted to the ablation electrode; then retract the RF ablation capsule through the cable, and the whole process ends. If ablation is needed again after evaluation, proceed to step j.

[0060] j. Adjust the external magnetic field to drive the capsule away from the lesion area, and then proceed to step ei.

[0061] In order to accurately control the retraction or extension state of the ablation electrode, the following methods can be used, see Fig.17 .

[0062] Assume that the reduction ratio of the planetary gear mechanism composed of the sun gear, planetary gear, inner ring gear, etc. is 1:3, that is, the sun gear rotates counterclockwise for one circle, and the suspension rotates clockwise for 1 / 3 circle. And assume that when the slide rotates clockwise around the sleeve for 4 circles, the ablation electrode moves from the lowest end (retracted state) to the highest end (extended state), that is, when the slide rotates clockwise around the sleeve for 4 circles, the ablation electrode extends; when the slide rotates counterclockwise around the sleeve for 4 circles, the ablation electrode retracts.

[0063] a) First determine whether the current state of the ablation electrode is contracted based on the rotation counter.

[0064] b) If it is in the contracted state, set the motor controller to enable: the rotation direction (counterclockwise) and the rotation counter are cleared;

[0065] c) Send pulses to the motor controller to make the driving shaft (motor shaft) rotate counterclockwise for one circle;

[0066] d) Read the xyz acceleration value of the MPU6050 acceleration sensor on the PCB board and integrate it;

[0067] e) Determine whether the slide attitude has changed. If the slide attitude has changed, the rotation counter is incremented by 1; if the slide attitude has not changed, proceed to step g)

[0068] f) Determine whether the count of the rotation counter is greater than or equal to 12. If so, set the current ablation electrode state to extended; end the operation.

[0069] g) Send an ablation electrode extension error message to the remote end, read the rotation counter count, and if the rotation counter count is not equal to 0, control the motor shaft to rotate clockwise so that the ablation electrode returns to the initial contracted state and ends the operation.

[0070] The end of the radiofrequency ablation capsule is connected to a 2mm diameter four-core Teflon soft cable to realize system power supply, communication and radiofrequency ablation. The CMOS optical (video) sensor combined with magnetic control technology and motor control can achieve stable gastric lesion positioning and effective radiofrequency treatment. The purpose of the present invention is to reduce preoperative links and alleviate patient pain.

[0071] The PCB chassis is equipped with the main cable socket and FPC socket, and also provides electrical connections for the ablation electrode and the corresponding pressure sensor.

[0072] The MP6050 acceleration sensor can obtain the attitude data of the slide.

[0073] The stacked flexible circuit board FPC can be folded and stretched. It provides signal connection for optical sensors and white light LEDs. When the ablation electrode is extended, the FPC naturally folds in the space between the suspension's receiving groove and the slide chassis.

[0074] The present invention provides a radiofrequency ablation capsule for radiofrequency ablation treatment of the stomach, which contains a bipolar radiofrequency ablation electrode, the extension and retraction of the ablation electrode can be controlled by instructions, and the distribution of the ablation electrode around the lesion can be adjusted by rotating the suspension to ensure the effectiveness of multiple ablations.

[0075] The protection scope of this patent includes but is not limited to the above implementation methods. The protection scope of this patent shall be based on the claims. Any replacement, deformation, and improvement of this technology that can be easily thought of by technicians in this field shall fall within the protection scope of this patent.

Claims

1. A radiofrequency ablation capsule, comprising a permanent magnet housing and an ablation electrode electrically connected to a PCB, characterized in that: The outer periphery of the suspension is rotatably arranged on the inner periphery of the upper end of the permanent magnet shell, and an inner gear ring is arranged on the lower part of the suspension; the lower end of the ablation electrode and the PCB board are arranged on a slide that can move up and down in the permanent magnet shell, the slide is located below the suspension, and a motor fixed to the lower end of the permanent magnet shell is arranged below the slide; the motor shaft passes through a sleeve that is fixed on the permanent magnet shell and extends upward, and the top end of the motor shaft is fixed with a sun gear; the upper end of the sleeve is fixed with a planetary gear carrier, and the planetary gears rotatably arranged on the planetary gear carrier are meshed with the sun gear and the inner gear ring at the same time; the upper part of the ablation electrode passes through a guide hole opened on the suspension; the sleeve passes through a spiral hole opened on the slide, the lower part of the outer periphery of the sleeve is a spiral section with a spiral line that matches the spiral hole, and the upper part of the outer periphery of the sleeve is a smooth section with a diameter smaller than the spiral hole; The motor is working, the motor shaft rotates in a certain direction, and the sun gear drives the inner ring gear, suspension, slide, and ablation electrode to rotate in the positive direction relative to the permanent magnet housing and sleeve through the planetary gear. At the same time, the slide and ablation electrode move upward relative to the sleeve and suspension until the slide moves upward to the smooth section of the sleeve and the slide is separated from the cooperation with the spiral section. Then, the slide and ablation electrode stop moving upward. At this time, the motor shaft continues to rotate in a certain direction, and the inner ring gear, suspension, slide, and ablation electrode continue to rotate in the positive direction relative to the permanent magnet housing and sleeve. The motor shaft rotates in a direction opposite to a certain direction. The sun gear drives the inner ring gear, suspension, slide, and ablation electrode to rotate in the opposite direction relative to the permanent magnet housing and sleeve through the planetary gear. At the same time, the slide cooperates with the spiral section of the sleeve, and the slide and ablation electrode move downward relative to the sleeve and suspension.

2. The radiofrequency ablation capsule according to claim 1, characterized in that: The upper end of the suspension has an LED light for lighting and an optical sensor for shooting.

3. The radiofrequency ablation capsule according to claim 2, characterized in that: The upper part of the stacked flexible circuit board is electrically connected to the PCB board, and the LED lamp and the optical sensor are electrically connected to the upper part of the stacked flexible circuit board.

4. The radiofrequency ablation capsule according to claim 3, characterized in that: The bottom of the suspension is provided with a receiving groove for receiving the stacked flexible circuit boards.

5. The radiofrequency ablation capsule according to claim 1, characterized in that: The cable passes through the lower end of the permanent magnet housing and is electrically connected to a socket connected to the lower part of the PCB board.

6. The radiofrequency ablation capsule according to claim 1, characterized in that: There are two ablation electrodes, which are symmetrically arranged with the axis of the motor shaft as the center.

7. The radiofrequency ablation capsule according to claim 1, characterized in that: The ablation electrode comprises an electrode sleeve fixed on a slide table, extending up and down and passing through a guide hole, an electrode slidably arranged in the electrode sleeve, and a pressure sensor arranged between the lower end of the electrode and the lower part of the electrode sleeve.

8. The radiofrequency ablation capsule according to claim 8, characterized in that: It also includes an elastic material arranged between the pressure sensor and the lower end of the electrode sleeve.

9. The radiofrequency ablation capsule according to claim 3, characterized in that: It also includes a processor, the motor is a stepper motor, and the optical sensor, the pressure sensor, and the stepper motor controller are electrically connected to the processor and work under the control of the processor.

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