Fermentation production device for biological medicine

Abstract

The invention relates to the technical field of biological medicine fermentation production, and discloses a biological medicine fermentation production device which comprises a bottom plate for supporting a biological medicine fermentation device, an equipment main body is arranged at the top of the bottom plate, and the equipment main body comprises an auxiliary device fixedly connected to the top of the bottom plate, the auxiliary device is arranged at the top of the bottom plate and used for shaking the biological medicine in the horizontal direction in the fermentation stirring process of the biological medicine and fermentation liquor, so that the overall stirring effect of the device is improved, and a user can use the device conveniently; the driving device is used for providing power for operation of the left side of the fermentation production device for the biological medicine and assisting follow-up assemblies to further improve the mixing and stirring effect of the device, the situation that a large number of bubbles appear in the stirring and mixing process of the device is reduced, and a user can use the device conveniently; the device has the advantages of improving the mixing and stirring effects of the device, being convenient for users to use and the like.

Description

Technical Field

[0001] The invention relates to the technical field of biomedical fermentation production, and in particular to a biomedical fermentation production device. Background Art

[0002] In production, fermentation tanks are used as equipment for biopharmaceutical fermentation production. The main body of the fermentation tank is generally a main cylinder made of stainless steel plates. It can withstand steam sterilization, has certain operational flexibility, strong material and energy transfer performance, and can be adjusted to a certain extent, making it suitable for the production of a variety of products.

[0003] Publication No.: CN220665288U discloses a biological fermentation culture tank with a cleaning mechanism, characterized in that the cleaning mechanism includes: a driving device, the driving device is installed on the top of the tank body of the culture tank and is located outside the tank body, a driving shaft is installed on the driving device and is located inside the tank body, the driving device is used to drive the driving shaft to rotate, and a stirring paddle, the stirring paddle is installed on the driving shaft, the device realizes thorough cleaning of the biological fermentation culture tank, and can save cleaning time and improve cleaning efficiency. However, in actual use, when the device and the existing equipment ferment the biomedicine inside the fermentation tank, the biomedicine and the fermentation liquid need to be mixed and stirred, and in order to prevent a large number of bubbles from being generated during the stirring process, the user usually chooses to add a defoaming agent to the fermentation tank for defoaming treatment, but the prior art usually uses a stirring rod and a stirring blade for stirring during stirring, which makes the stirring force of the part away from the stirring rod small, and the device needs to increase the stirring speed to complete the stirring of this part of the biomedicine. Increasing the stirring rate makes the part close to the stirring rod easy to be over-stirred, thereby generating a large number of bubbles. The stirring effect of the existing equipment on the biomedicine during the fermentation process has further room for improvement. Summary of the invention

[0004] In view of the deficiencies in the prior art, the present invention provides a biomedical fermentation production device, which has the advantages of improving the mixing and stirring effect of the device and being easy for users to use.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical scheme: a biomedical fermentation production device, comprising: a bottom plate, an equipment body, an auxiliary device, a through groove, a first rotary drive component, a first rotating shaft, a toothed disc, a return groove plate, a movable plate, a guide sleeve, a mounting member, a slider, a mounting plate, a driving device, a second rotary drive component, a second rotating shaft, a first bevel gear, a first shaft rod, a side plate, a second shaft rod, a second bevel gear, a third bevel gear, a first fixed rod, a bottom plate, a fermentation device, a feed door, a second fixed rod, a rotating member, a drainage blade, a first linear drive component, a first output rod, a crushing plate, a stirring rod, a first connecting plate, a first stirring blade, a drug delivery device, a bracket, a storage bin, a second linear drive component, a second output rod, a movable bin, a piston plate, a movable rod, an output pipe, a first one-way valve, an extraction pipe, a second one-way valve, a processing plate, a second connecting plate, a second stirring blade, a push rod, a rotating disk, a drug delivery disk, a movable groove, a spray head, a sliding member, and a gas delivery bin.

[0006] The positions and connection relationships of the above structures are as follows: A biomedical fermentation production device includes a bottom plate for supporting the biomedical fermentation device, and a device body is arranged on the top of the bottom plate, and the device body includes: An auxiliary device, which is fixedly connected to the top of the bottom plate, is used to shake the biopharmaceutical in the horizontal direction during the fermentation and stirring of the biopharmaceutical and the fermentation liquid, so as to improve the overall stirring effect of the device and facilitate user use; A driving device is arranged on the top of the bottom plate, and is used to provide power for the left side operation of the biomedical fermentation production device, and assist subsequent components to further improve the mixing and stirring effect of the device, reduce the occurrence of a large number of bubbles during the mixing process of the device, and facilitate user use; A fermentation device, which is fixedly connected to the bottom of the driving device, is used to store biomedicine and fermentation liquid and cooperates with the driving device to further improve the mixing and stirring effect of the device, so that the mixing degree of each part of the mixed liquid of biomedicine and fermentation liquid is the same, which is convenient for users to use; The drug delivery device is fixedly connected to the top of the fermentation device. The drug delivery device is used to transport the defoaming agent inside the fermentation device and adjust the delivery direction of the defoaming agent at the same time, so as to further improve the mixing degree of the defoaming agent in the fermentation liquid and the biopharmaceutical, reduce the bubble generation phenomenon of the device, improve the stirring effect of the device, and facilitate user use.

[0007] Preferably, the auxiliary device includes a through groove, which is opened at the top of the auxiliary device, and a first rotation drive component is fixedly connected to the inner wall of the bottom side of the auxiliary device, and the first rotation drive component is configured as a driving motor, and a first rotating shaft is fixedly connected to the top output end of the first rotation drive component, and a gear disk is fixedly connected to the end of the first rotating shaft away from the first rotation drive component, and the gear disk is only provided with half of the teeth, and a return groove plate is movably connected to the outer surface of the gear disk, and a plurality of teeth are fixedly connected to the inside of the return groove plate, and the gear disk is meshed with the teeth and connected to the inside of the return groove plate, and movable plates are fixedly connected to the left and right sides of the return groove plate to ensure normal operation of the device.

[0008] Preferably, the auxiliary device also includes two guide sleeves, which are respectively sleeved on the outer surface of the movable plate, the bottom of the two guide sleeves are fixedly connected with mounting parts, the mounting parts are fixedly connected to the inner wall of the bottom side of the auxiliary device, the top of the two movable plates are fixedly connected with sliders, the sliders extend to the outer side of the top of the auxiliary device through the through groove, the extended part of the slider is fixedly connected with a mounting plate, and the top of the mounting plate is provided with a drug delivery device to ensure the normal operation of the device.

[0009] Preferably, the driving device includes a second rotary drive component, which is fixedly connected to the inner wall of the top side of the driving device. The second rotary drive component is configured as a driving motor. A second rotating shaft is fixedly connected to the bottom output end of the second rotary drive component. An end of the second rotating shaft away from the second rotary drive component is fixedly connected to a first bevel gear. The bottom of the first bevel gear is fixedly connected to a first shaft rod to ensure normal operation of the device.

[0010] Preferably, the driving device also includes a side plate, which is fixedly connected to the interior of the driving device and the side plate is arranged at the rear side of the interior of the driving device, the front end of the side plate is rotatably connected to the second shaft rod, the end of the second shaft rod away from the side plate is fixedly connected to the second bevel gear, the first bevel gear is meshingly connected to the top of the second bevel gear, the bottom of the second bevel gear is meshingly connected to the third bevel gear, the third bevel gear is provided with a through hole inside, four first fixed rods are fixedly connected to the bottom of the third bevel gear, the end of the first fixed rod away from the third bevel gear is fixedly connected to the chassis, the chassis extends to the interior of the fermentation device and the chassis is rotatably connected to the driving device, the first shaft rod penetrates the third bevel gear and the chassis and extends to the interior of the fermentation device to ensure normal operation of the device.

[0011] Preferably, the fermentation device includes a feed door, which is movably connected to the front end surface of the fermentation device, three second fixed rods are fixedly connected to the extended part of the chassis, the bottom of the three second fixed rods is fixedly connected to a rotating part, and the end of the rotating part away from the second fixed rod is fixedly connected to a drainage blade, the three drainage blades are arranged in a spiral shape and the three drainage blades are movably connected to the bottom inner wall of the fermentation device to ensure the normal operation of the device.

[0012] Preferably, the fermentation device also includes a first linear drive component, which is fixedly connected to the extended part of the first shaft rod, the first linear drive component is configured as a hydraulic cylinder, and the first output rod is differentially connected to the bottom output end of the first linear drive component, and the end of the first output rod away from the first linear drive component is fixedly connected to a crushing plate, and the bottom of the crushing plate is fixedly connected to a plurality of crushing teeth, and a stirring rod is fixedly connected to the bottom center of the crushing plate, and a plurality of first connecting plates are fixedly connected to the outer surface of the stirring rod, and the first connecting plate is fixedly connected to the end away from the stirring rod with a first stirring blade, and the rotation range of the plurality of first stirring blades is smaller than the rotation range of the three drainage blades, so as to ensure the normal operation of the device.

[0013] Preferably, the drug delivery device includes a bracket, which is fixedly connected to the bottom of the drug delivery device and the bracket is fixedly connected to the top of the mounting plate. A storage bin is rotatably connected to the inner wall of the bottom side of the drug delivery device. Defoaming agent is stored in the storage bin. A second linear drive component is fixedly connected to the top of the storage bin. The second linear drive component is configured as a hydraulic cylinder. A second output rod is differentially connected to the top output end of the second linear drive component. The second output rod is fixedly connected to a movable bin at one end away from the second linear drive component to ensure normal operation of the device.

[0014] Preferably, the drug delivery device also includes a piston plate, which is movably connected to the interior of the movable bin, and a movable rod is fixedly connected to the top of the piston plate, which penetrates the movable bin and extends to the outside of the top of the movable bin, an extraction pipe is fixedly connected to the inner wall of the left end of the movable bin, and the other end of the extraction pipe is fixedly connected to the top of the storage bin, a second one-way valve is fixedly connected to the connection between the extraction pipe and the movable bin, an output pipe is fixedly connected to the right inner wall of the movable bin, and a first one-way valve is fixedly connected to the connection between the output pipe and the movable bin, and a plurality of processing plates are fixedly connected to the top of the movable bin, and a rotating disk is provided on the top of the movable bin, the processing plate, the movable rod and the conveying pipe penetrate the rotating disk and extend to the top of the rotating disk, and the rotating disk is rotatably connected to the inner wall of the bottom side of the drug delivery device, the processing plate, the movable rod and the conveying pipe all extend to the interior of the fermentation device, and the end of the extended part of the processing plate away from the movable rod is fixedly connected to the second connecting plate, and the end of the second connecting plate away from the processing plate is fixedly connected to the second stirring blade, and the top of the extended part of the processing plate is fixedly connected to a push rod to ensure the normal operation of the device.

[0015] Preferably, the drug delivery device also includes a drug delivery tray, which is arranged on the top of the extended part of the processing plate, and a movable groove is opened at one end of the drug delivery device close to the push rod, and a spray head is rotatably connected inside the movable groove, and one end of the spray head away from the center of the drug delivery tray is fixedly connected to a sliding member, the push rod is movably connected to the inside of the sliding member, and an air delivery bin is fixedly connected to the center of the drug delivery tray and extends to the bottom of the drug delivery tray, and a plurality of spray heads are communicated with the air delivery bin, and the extended part of the delivery pipe is fixedly connected to the bottom of the air delivery bin, and the air delivery bin is arranged in a circular ring shape, and the extended part of the movable rod is movably connected to the bottom of the air delivery bin, and the bottom of the stirring rod is movably connected to the inside of the air delivery bin, and the stirring rod is sleeved inside the movable rod and the stirring rod is limited inside the movable rod to ensure the normal operation of the device.

[0016] Beneficial Effects 1. The biomedical fermentation production device can shake the biomedical and fermentation liquid in the horizontal direction by turning on the auxiliary device during the fermentation and stirring of the biomedical and fermentation liquid, so as to improve the overall stirring effect of the device and the mixing and stirring effect of the device, which is convenient for users to use.

[0017] 2. The biomedical fermentation production device, by turning on the fermentation device, prevents the fermentation liquid from being far away from the stirring rod, the biomedical stirring force is weak, the device needs to increase the stirring speed to complete the stirring of the biomedical at that location, and the increased stirring rate makes the part close to the stirring rod prone to excessive stirring, thereby generating a large number of bubbles. The device reduces the generation of bubbles while improving the mixing and stirring degree of the device, which is convenient for users to use.

[0018] 3. The biomedical fermentation production device reduces bubbles generated by the fermentation liquid and the biomedicine by opening the drug delivery device to improve the mixing of the defoaming agent in the fermentation liquid and the biomedicine, thereby improving the mixing and stirring effect of the device and being convenient for users to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic diagram of the appearance structure of a biomedical fermentation production device of the present invention; Figure 2 This is a schematic diagram of the internal structure of a biomedical fermentation production device of the present invention; Figure 3 This is a schematic diagram of the structure of the first rotary drive component of a biomedical fermentation production device of the present invention; Figure 4 This is a schematic diagram of the main appearance structure of a biomedical fermentation production device of the present invention; Figure 5 This is a schematic diagram of the internal structure of a biomedical fermentation production device of the present invention; Figure 6This is a schematic diagram of the internal structure of a driving device for a biomedical fermentation production device of the present invention; Figure 7 This is a schematic diagram of the internal structure of a fermentation device for a biomedical fermentation production device of the present invention; Figure 8 This is a schematic diagram of the internal structure of a drug delivery device for a biomedical fermentation production device of the present invention; Fig. 9 This is a schematic diagram of the internal structure of a movable chamber of a biomedical fermentation production device of the present invention; Fig.10 This is a schematic diagram of the structure of a rotating disk of a biomedical fermentation production device of the present invention; Fig.11 This is a schematic diagram of the structure of a drug delivery plate of a biomedical fermentation production device of the present invention.

[0020] In the figure: 1, bottom plate; 2, equipment body; 3, auxiliary device; 30, through groove; 31, first rotary drive assembly; 310, first rotating shaft; 32, toothed disc; 33, return groove plate; 330, movable plate; 331, guide sleeve; 332, mounting member; 34, slider; 35, mounting plate; 4, driving device; 40, second rotary drive assembly; 400, second rotating shaft; 41, first bevel gear; 410, first shaft rod; 42, side plate; 420, second shaft rod; 421, second bevel gear; 43, third bevel gear; 430, first fixed rod; 431, bottom plate; 5, fermentation device; 50, feed door; 51, second fixed rod; 52, rotating member; 520, drainage blade; 53. first linear drive assembly; 530. first output rod; 54. crushing plate; 540. stirring rod; 541. first connecting plate; 542. first stirring blade; 6. drug delivery device; 60. bracket; 61. storage bin; 610. second linear drive assembly; 611. second output rod; 62. movable bin; 620. piston plate; 621. movable rod; 622. output pipe; 623. first one-way valve; 624. extraction pipe; 625. second one-way valve; 63. processing plate; 630. second connecting plate; 631. second stirring blade; 632. push rod; 64. rotating disk; 65. drug delivery disk; 650. movable slot; 651. spray head; 652. sliding member; 66. gas delivery bin. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0022] Embodiment 1 See also Figures 1 to 11 A biomedical fermentation production device includes a base plate 1 for supporting a biomedical fermentation device 5, a device body 2 is arranged on the top of the base plate 1, and the device body 2 includes: The auxiliary device 3 is fixedly connected to the top of the bottom plate 1. The auxiliary device 3 is used to shake the biomedicine in the horizontal direction during the fermentation and stirring of the biomedicine and the fermentation liquid, so as to improve the overall stirring effect of the device and facilitate the use of the user; The driving device 4 is arranged on the top of the bottom plate 1. The driving device 4 is used to provide power for the left side operation of the biomedical fermentation production device and assist the subsequent components to further improve the mixing and stirring effect of the device, reduce the occurrence of a large number of bubbles in the device during the mixing and stirring process, and facilitate user use; The fermentation device 5 is fixedly connected to the bottom of the driving device 4. The fermentation device 5 is used to store the biomedicine and the fermentation liquid and cooperate with the driving device 4 to further improve the mixing and stirring effect of the device, so that the mixing degree of each part of the mixed liquid of the biomedicine and the fermentation liquid is the same, which is convenient for users to use; The drug delivery device 6 is fixedly connected to the top of the fermentation device 5. The drug delivery device 6 is used to transport the defoaming agent inside the fermentation device 5 and adjust the delivery direction of the defoaming agent to further improve the mixing degree of the defoaming agent in the fermentation liquid and the biopharmaceutical, reduce the bubble generation phenomenon of the device, improve the stirring effect of the device, and facilitate user use.

[0023] The auxiliary device 3 includes a through slot 30, which is opened at the top of the auxiliary device 3. A first rotation drive component 31 is fixedly connected to the inner wall of the bottom side of the auxiliary device 3. The first rotation drive component 31 is configured as a driving motor. A first rotating shaft 310 is fixedly connected to the top output end of the first rotation drive component 31. A toothed disc 32 is fixedly connected to the end of the first rotating shaft 310 away from the first rotation drive component 31. The toothed disc 32 is only provided with half of the teeth. A return groove plate 33 is movably connected to the outer surface of the toothed disc 32. A plurality of teeth are fixedly connected to the inside of the return groove plate 33. The toothed disc 32 is meshed with the teeth and is connected to the inside of the return groove plate 33. A movable plate 330 is fixedly connected to the left and right sides of the return groove plate 33 to ensure the normal operation of the device.

[0024] The auxiliary device 3 also includes two guide sleeves 331, which are respectively sleeved on the outer surface of the movable plate 330. The bottoms of the two guide sleeves 331 are fixedly connected with mounting members 332, and the mounting members 332 are fixedly connected to the inner wall of the bottom side of the auxiliary device 3. The tops of the two movable plates 330 are fixedly connected with sliders 34, and the sliders 34 extend to the outer side of the top of the auxiliary device 3 through the through grooves 30. The extended part of the sliders 34 is fixedly connected with mounting plates 35, and the top of the mounting plates 35 is provided with a drug delivery device 6 to ensure the normal operation of the device.

[0025] Embodiment 2 See also Figures 1 to 11 Further on the basis of embodiment 1, the driving device 4 includes a second rotating driving component 40, which is fixedly connected to the inner wall of the top side of the driving device 4. The second rotating driving component 40 is configured as a driving motor. A second rotating shaft 400 is fixedly connected to the bottom output end of the second rotating driving component 40. An end of the second rotating shaft 400 away from the second rotating driving component 40 is fixedly connected to a first bevel gear 41. The bottom of the first bevel gear 41 is fixedly connected to a first shaft rod 410 to ensure the normal operation of the device.

[0026] The driving device 4 also includes a side plate 42, which is fixedly connected to the interior of the driving device 4 and the side plate 42 is arranged at the rear side of the interior of the driving device 4. The front end of the side plate 42 is rotatably connected to the second shaft rod 420, and the end of the second shaft rod 420 away from the side plate 42 is fixedly connected to the second bevel gear 421, the first bevel gear 41 is meshedly connected to the top of the second bevel gear 421, and the bottom of the second bevel gear 421 is meshedly connected to the third bevel gear 43, and the third bevel gear 43 is provided with a through hole inside. Four first fixed rods 430 are fixedly connected to the bottom of the third bevel gear 43, and the end of the first fixed rod 430 away from the third bevel gear 43 is fixedly connected to the chassis 431, the chassis 431 extends to the interior of the fermentation device 5 and the chassis 431 is rotatably connected to the driving device 4, the first shaft rod 410 passes through the third bevel gear 43 and the chassis 431 and extends to the interior of the fermentation device 5 to ensure the normal operation of the device.

[0027] The fermentation device 5 includes a feed gate 50, which is movably connected to the front end surface of the fermentation device 5, and three second fixed rods 51 are fixedly connected to the extended part of the chassis 431. The bottom of the three second fixed rods 51 is fixedly connected to a rotating member 52, and the end of the rotating member 52 away from the second fixed rod 51 is fixedly connected to a drainage blade 520. The three drainage blades 520 are arranged in a spiral shape and the three drainage blades 520 are all movably connected to the bottom inner wall of the fermentation device 5 to ensure the normal operation of the device.

[0028] The fermentation device 5 also includes a first linear drive component 53, which is fixedly connected to the extended part of the first shaft 410. The first linear drive component 53 is configured as a hydraulic cylinder. The first output rod 530 is differentially connected to the bottom output end of the first linear drive component 53. The end of the first output rod 530 away from the first linear drive component 53 is fixedly connected to a crushing plate 54. The bottom of the crushing plate 54 is fixedly connected to a plurality of crushing teeth. A stirring rod 540 is fixedly connected to the bottom center of the crushing plate 54. A plurality of first connecting plates 541 are fixedly connected to the outer surface of the stirring rod 540. The first connecting plates 541 are fixedly connected to the first stirring blades 542 at one end away from the stirring rod 540. The rotation range of the plurality of first stirring blades 542 is smaller than the rotation range of the three drainage blades 520, thereby ensuring the normal operation of the device.

[0029] Embodiment 3 See also Figures 1 to 11 On the basis of the second embodiment, the drug delivery device 6 includes a bracket 60, which is fixedly connected to the bottom of the drug delivery device 6 and the bracket 60 is fixedly connected to the top of the mounting plate 35. A storage bin 61 is rotatably connected to the inner wall of the bottom side of the drug delivery device 6. The storage bin 61 stores defoaming agent inside. A second linear drive component 610 is fixedly connected to the top of the storage bin 61. The second linear drive component 610 is configured as a hydraulic cylinder. A second output rod 611 is differentially connected to the top output end of the second linear drive component 610. The second output rod 611 is fixedly connected to the movable bin 62 at one end away from the second linear drive component 610 to ensure the normal operation of the device.

[0030] The drug delivery device 6 also includes a piston plate 620, which is movably connected to the inside of the movable bin 62. A movable rod 621 is fixedly connected to the top of the piston plate 620, which penetrates the movable bin 62 and extends to the outside of the top of the movable bin 62. An extraction tube 624 is fixedly connected to the inner wall of the left end of the movable bin 62. The other end of the extraction tube 624 is fixedly connected to the top of the storage bin 61. A second one-way valve 625 is fixedly connected to the connection between the extraction tube 624 and the movable bin 62. An output tube 622 is fixedly connected to the inner wall of the right side of the movable bin 62. A first one-way valve 623 is fixedly connected to the connection between the output tube 622 and the movable bin 62. The top of the movable bin 62 is fixedly connected to There are a processing plate 63 and a rotating disk 64 on the top of the movable bin 62. The processing plate 63, the movable rod 621, and the conveying tube 622 penetrate the rotating disk 64 and extend to the top of the rotating disk 64. The rotating disk 64 is rotatably connected to the inner wall of the bottom side of the drug delivery device 6. The processing plate 63, the movable rod 621, and the conveying tube 622 all extend to the interior of the fermentation device 5. The end of the extended part of the processing plate 63 away from the movable rod 621 is fixedly connected to the second connecting plate 630, and the end of the second connecting plate 630 away from the processing plate 63 is fixedly connected to the second stirring blade 631. The top of the extended part of the processing plate 63 is fixedly connected to the push rod 632 to ensure the normal operation of the device.

[0031] The drug delivery device 6 also includes a drug delivery tray 65, which is arranged on the top of the extended portion of the processing plate 63. The drug delivery device 6 is provided with a movable groove 650 at one end close to the push rod 632. A spray head 651 is rotatably connected inside the movable groove 650. The spray head 651 is fixedly connected to a sliding member 652 at one end away from the center of the drug delivery tray 65. The push rod 632 is movably connected to the inside of the sliding member 652. The center of the drug delivery tray 65 is fixedly connected to an air delivery bin 66, and the air delivery bin 66 extends to the drug delivery tray. At the bottom of 65, several spray heads 651 are interconnected with the gas delivery bin 66, the extended part of the delivery pipe 622 is fixedly connected to the bottom of the gas delivery bin 66, the gas delivery bin 66 is arranged in a circular ring shape, the extended part of the movable rod 621 is movably connected to the bottom of the gas delivery bin 66, the bottom of the stirring rod 540 is movably connected to the inside of the gas delivery bin 66, the stirring rod 540 is sleeved inside the movable rod 621 and the stirring rod 540 is limited inside the movable rod 621 to ensure the normal operation of the device.

[0032] Working principle: biopharmaceuticals and fermentation liquid are injected into the fermentation device 5 through the feed door 50, and then the second rotary drive component 40 is turned on, the second rotary drive component 40 is turned on to drive the second rotating shaft 400 to rotate, the second rotating shaft 400 rotates to drive the first bevel gear 41 to rotate, the first bevel gear 41 rotates to drive the first shaft rod 410 and the second bevel gear 421 to rotate, the first shaft rod 410 rotates to drive the first linear drive component 53 and the first output rod 530 to rotate, the first output rod 530 rotates to drive the crushing plate 54 to rotate, the crushing plate 54 rotates through the stirring rod 540 and the first connecting plate 541 to drive a plurality of first stirring blades 542 to rotate, and the stirring rod 540 is sleeved on the movable rod 621. The stirring rod 540 is inside the movable rod 621 and is limited in position. The stirring rod 540 moves up and down in the movable rod 621 and the movable rod 621 remains stationary. The rotation of the stirring rod 540 can drive the movable rod 621 to rotate together. The rotation of the movable rod 621 drives the drug delivery plate 65, the processing plate 63, the rotating plate 64, the movable bin 62, the second linear drive assembly 610, and the storage bin 61 to rotate. At this time, the rotation of the processing plate 63 can drive the second stirring blade 631 to rotate through the second connecting plate 630. At this time, the coaxial rotation of the first stirring blade 542 and the second stirring blade 631 mixes and stirs the fermentation liquid and the biomedicine. In the above steps, the rotation of the second bevel gear 421 can drive the third bevel gear 43 to rotate with the first bevel gear 41. The third bevel gear 43 rotates in the opposite direction, and drives the chassis 431 to rotate through the first fixed rods 430. The chassis 431 rotates through the second fixed rod 51 to drive the rotating member 52 to rotate. The rotating member 52 rotates and drives the three guide vanes 520 to make circular motion. Since the guide vanes 520 are set in a spiral shape, the rotation of the guide vanes 520 at this time makes the fermentation liquid and biomedicine away from one end of the stirring rod 540 spiral and continuously approach the stirring rod 540. Since the spiral formed by the rotation of the guide vanes 520 is opposite to the direction of the stirring rod 540, the fermentation liquid and biomedicine at the two places continuously collide and continue to blend, which increases the turbulence of the overall fermentation liquid and biomedicine inside the fermentation device 5, thereby making the fermentation liquid and biomedicine at this place The fermentation liquid and the biomedicine are mixed more fully, avoiding the situation that the fermentation liquid and the biomedicine far away from the stirring rod 540 have weak stirring force, the device needs to increase the stirring speed to complete the stirring of the biomedicine at this place, and the stirring rate is increased so that the part close to the stirring rod 540 is easily over-stirred, thereby generating a large number of bubbles. When a large number of bubbles appear at the stirring rod 540, the device can start the first linear drive component 53, and the first linear drive component 53 is turned on to push out and move downward the first output rod 530. The downward movement of the first output rod 530 drives the crushing plate 54 and the stirring rod 540 to move downward until the crushing plate 54 moves to the mixed liquid surface of the fermentation liquid and the biomedicine. Since the bubble density is small, it will float up. At this time, the rotation of the crushing plate 54 can eliminate the floating bubbles.Reduce the bubble generation of the device while improving the mixing degree of the device, making it easier for users to use; In the above steps, the first rotary drive component 31 is turned on, and the first rotary drive component 31 is turned on to drive the first rotating shaft 310 to rotate. The rotation of the first rotating shaft 310 drives the toothed disc 32 to rotate. Since the toothed disc 32 is only provided with half of the latching teeth, the rotation of the toothed disc 32 can drive the return groove plate 33 to perform linear reciprocating motion. The movement of the return groove plate 33 drives the entire device body 2 to perform linear reciprocating motion through the through groove 30, the two sliders 34, and the mounting plate 35. The movable plate 330, the guide sleeve 331, and the mounting member 332 are used to limit the movement of the return groove plate 33. During the fermentation and stirring of the biopharmaceutical and the fermentation liquid, the device can shake the biopharmaceutical and the fermentation liquid in the horizontal direction to enhance the overall stirring effect of the device, enhance the mixing and stirring effect of the device, and facilitate user use. In the above steps, if the device selects a fermentation liquid with a higher concentration and more bubbles are generated, the device can start the second linear drive component 610 at this time. The second linear drive component 610 is turned on to drive the second output rod 611 to move upward, and the second output rod 611 moves upward to drive the movable bin 62 to move upward. The upward movement of the movable bin 62 causes the air pressure inside the movable bin 62 to change. At this time, the defoaming agent inside the movable bin 62 is transported to the gas transmission bin 66 through the delivery pipe 622. The second one-way valve 625 is used to prevent the defoaming agent in the storage bin 61 from flowing back. The upward movement of the movable bin 62 can drive the processing plate 63 to move upward. The upward movement of the processing plate 63 drives the spray head 651 to gradually rotate in the sliding member 652 through the push rod 632. When the movable bin 62 moves to the maximum distance, the spray head 651 rotates to one hundred and eighty degrees. Ten degrees, and during the rotation of the spray head 651, the spray head 651 continuously sprays the defoaming agent into the fermentation liquid and the biomedicine. At this time, the rotation of the spray head 651 further improves the mixing of the defoaming agent in the fermentation liquid and the biomedicine near one end of the stirring rod 540, and the setting of the drainage blade 520 can make the defoaming agent at the end away from the stirring rod 540 also be well mixed, and the bubbles generated by the fermentation liquid and the biomedicine are reduced by improving the mixing of the defoaming agent in the fermentation liquid and the biomedicine. The first linear drive component 53 drives the first output rod 530 to reset. Similarly, the movable bin 62 can extract the defoaming agent in the storage bin 61 through the extraction pipe 624. The first one-way valve 623 is used to prevent the fermentation liquid and the biomedicine from flowing back, improve the mixing and stirring effect of the device, and facilitate user use.

[0033] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A biomedical fermentation production device, comprising a base plate (1) for supporting a biomedical fermentation device (5), characterized in that: A device body (2) is arranged on the top of the base plate (1), and the device body (2) comprises: An auxiliary device (3) is fixedly connected to the top of the bottom plate (1), and is used to shake the biopharmaceutical in a horizontal direction during the fermentation and stirring of the biopharmaceutical and the fermentation liquid, so as to enhance the overall stirring effect of the device and facilitate use by the user; A driving device (4) is arranged on the top of the bottom plate (1), and is used to provide power for the left side operation of the biomedical fermentation production device, while assisting subsequent components to further improve the mixing and stirring effect of the device, reduce the occurrence of a large number of bubbles during the mixing and stirring process of the device, and facilitate user use; A fermentation device (5) is fixedly connected to the bottom of the driving device (4). The fermentation device (5) is used to store the biopharmaceutical and the fermentation liquid and cooperates with the driving device (4) to further enhance the mixing and stirring effect of the device, so that the mixing degree of each part of the mixed liquid of the biopharmaceutical and the fermentation liquid is the same, which is convenient for users to use; The drug delivery device (6) is fixedly connected to the top of the fermentation device (5). The drug delivery device (6) is used to adjust the delivery direction of the defoaming agent while delivering the defoaming agent inside the fermentation device (5), so as to further improve the mixing degree of the defoaming agent in the fermentation liquid and the biopharmaceutical, reduce the bubble generation phenomenon of the device, improve the stirring effect of the device, and facilitate user use.

2. A biomedical fermentation production device according to claim 1, characterized in that: The auxiliary device (3) comprises a through slot (30) which is opened at the top of the auxiliary device (3); a first rotary drive assembly (31) is fixedly connected to the inner wall of the bottom side of the auxiliary device (3); the first rotary drive assembly (31) is configured as a drive motor; a first rotating shaft (310) is fixedly connected to the top output end of the first rotary drive assembly (31); a toothed disc (32) is fixedly connected to one end of the first rotating shaft (310) away from the first rotary drive assembly (31); the toothed disc (32) is only provided with half of the latching teeth; a return groove plate (33) is movably connected to the outer surface of the toothed disc (32); a plurality of latching teeth are fixedly connected to the interior of the return groove plate (33); the toothed disc (32) is meshedly connected to the interior of the return groove plate (33) through the latching teeth; and movable plates (330) are fixedly connected to the left and right sides of the return groove plate (33).

3. A biomedical fermentation production device according to claim 2, characterized in that: The auxiliary device (3) further comprises two guide sleeves (331) which are respectively sleeved on the outer surface of the movable plate (330); the bottoms of the two guide sleeves (331) are fixedly connected to mounting members (332); the mounting members (332) are fixedly connected to the inner wall of the bottom side of the auxiliary device (3); the tops of the two movable plates (330) are fixedly connected to sliders (34); the sliders (34) extend through the through slots (30) to the outer side of the top of the auxiliary device (3); the extended portion of the sliders (34) is fixedly connected to a mounting plate (35); and the top of the mounting plate (35) is provided with a drug delivery device (6).

4. A biomedical fermentation production device according to claim 3, characterized in that: The driving device (4) comprises a second rotating driving assembly (40) which is fixedly connected to the inner wall of the top side of the driving device (4); the second rotating driving assembly (40) is configured as a driving motor; a second rotating shaft (400) is fixedly connected to the bottom output end of the second rotating driving assembly (40); an end of the second rotating shaft (400) away from the second rotating driving assembly (40) is fixedly connected to a first bevel gear (41); and a first shaft (410) is fixedly connected to the bottom of the first bevel gear (41).

5. A biomedical fermentation production device according to claim 4, characterized in that: The driving device (4) further comprises a side plate (42) which is fixedly connected to the inside of the driving device (4) and is arranged at the rear side of the inside of the driving device (4); the front end of the side plate (42) is rotatably connected to a second shaft rod (420); an end of the second shaft rod (420) away from the side plate (42) is fixedly connected to a second bevel gear (421); the first bevel gear (41) is meshingly connected to the top of the second bevel gear (421); and the bottom of the second bevel gear (421) is meshingly connected to a third bevel gear. (43), a through hole is provided inside the third bevel gear (43), four first fixing rods (430) are fixedly connected to the bottom of the third bevel gear (43), one end of the first fixing rod (430) away from the third bevel gear (43) is fixedly connected to a chassis (431), the chassis (431) extends to the inside of the fermentation device (5) and the chassis (431) is rotatably connected to the driving device (4), and the first shaft (410) passes through the third bevel gear (43) and the chassis (431) and extends to the inside of the fermentation device (5).

6. A biomedical fermentation production device according to claim 5, characterized in that: The fermentation device (5) comprises a feed gate (50) which is movably connected to the front end surface of the fermentation device (5); three second fixed rods (51) are fixedly connected to the extended portion of the bottom plate (431); the bottoms of the three second fixed rods (51) are fixedly connected to rotating members (52); one end of the rotating member (52) away from the second fixed rods (51) is fixedly connected to a drainage blade (520); the three drainage blades (520) are arranged in a spiral shape and are all movably connected to the bottom inner wall of the fermentation device (5).

7. A biomedical fermentation production device according to claim 6, characterized in that: The fermentation device (5) further comprises a first linear drive assembly (53), which is fixedly connected to the extension portion of the first shaft (410). The first linear drive assembly (53) is configured as a hydraulic cylinder. A first output rod (530) is differentially connected to the bottom output end of the first linear drive assembly (53). A crushing plate (54) is fixedly connected to one end of the first output rod (530) away from the first linear drive assembly (53). A plurality of crushing teeth are fixedly connected to the bottom of the crushing plate (54). A stirring rod (540) is fixedly connected to the center of the bottom of the crushing plate (54). A plurality of first connecting plates (541) are fixedly connected to the outer surface of the stirring rod (540). A first stirring blade (542) is fixedly connected to one end of the first connecting plates (541) away from the stirring rod (540). The rotation range of the plurality of first stirring blades (542) is smaller than the rotation range of the three drainage blades (520).

8. The biomedical fermentation production device according to claim 3, characterized in that: The drug delivery device (6) comprises a bracket (60) which is fixedly connected to the bottom of the drug delivery device (6) and the bracket (60) is fixedly connected to the top of the mounting plate (35); a storage bin (61) is rotatably connected to the inner wall of the bottom side of the drug delivery device (6); a defoaming agent is stored in the storage bin (61); a second linear drive component (610) is fixedly connected to the top of the storage bin (61); the second linear drive component (610) is configured as a hydraulic cylinder; a second output rod (611) is differentially connected to the top output end of the second linear drive component (610); and a movable bin (62) is fixedly connected to one end of the second output rod (611) away from the second linear drive component (610).

9. A biomedical fermentation production device according to claim 7, characterized in that: The drug delivery device (6) further comprises a piston plate (620) which is movably connected to the interior of the movable bin (62); a movable rod (621) is fixedly connected to the top of the piston plate (620), which penetrates the movable bin (62) and extends to the outer side of the top of the movable bin (62); an extraction tube (624) is fixedly connected to the inner wall of the left end of the movable bin (62); the other end of the extraction tube (624) is fixedly connected to the top of the storage bin (61); a second one-way valve (625) is fixedly connected to the connection between the extraction tube (624) and the movable bin (62); an output tube (622) is fixedly connected to the inner wall of the right side of the movable bin (62); a first one-way valve (623) is fixedly connected to the connection between the output tube (622) and the movable bin (62); and a first one-way valve (624) is fixedly connected to the top of the movable bin (62). A plurality of processing plates (63) are connected, a rotating disk (64) is arranged on the top of the movable bin (62), the processing plates (63), the movable rod (621), and the conveying tube (622) penetrate the rotating disk (64) and extend to the top of the rotating disk (64), the rotating disk (64) is rotatably connected to the inner wall of the bottom side of the drug delivery device (6), the processing plates (63), the movable rod (621), and the conveying tube (622) all extend to the inside of the fermentation device (5), the end of the extended portion of the processing plate (63) away from the movable rod (621) is fixedly connected to a second connecting plate (630), the end of the second connecting plate (630) away from the processing plate (63) is fixedly connected to a second stirring blade (631), and the top of the extended portion of the processing plate (63) is fixedly connected to a push rod (632).

10. A biomedical fermentation production device according to claim 9, characterized in that: The drug delivery device (6) further comprises a drug delivery tray (65) which is arranged on the top of the extended portion of the processing plate (63). The drug delivery device (6) is provided with a movable groove (650) at one end close to the push rod (632). A spray head (651) is rotatably connected inside the movable groove (650). The spray head (651) is fixedly connected to one end away from the center of the drug delivery tray (65). The push rod (632) is movably connected inside the slide (652). An air delivery bin (66) is fixedly connected at the center of the drug delivery tray (65). 6) extends to the bottom of the medicine delivery tray (65), a plurality of spray heads (651) are interconnected with the gas delivery bin (66), an extended portion of the delivery pipe (622) is fixedly connected to the bottom of the gas delivery bin (66), the gas delivery bin (66) is arranged in a circular ring shape, an extended portion of the movable rod (621) is movably connected to the bottom of the gas delivery bin (66), a bottom of the stirring rod (540) is movably connected to the inside of the gas delivery bin (66), the stirring rod (540) is sleeved inside the movable rod (621), and the stirring rod (540) is limited inside the movable rod (621).

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