Preparation method of gum-protecting and tooth-strengthening toothpaste
By combining a variety of Chinese medicine extracts and essential oil extracts, gingival and tooth-retaining toothpaste is prepared, which solves the problem of poor effectiveness in treating gingivitis, periodontitis and oral ulcers, and achieves significant auxiliary treatment effects on a variety of oral inflammatory symptoms.
Patent Information
- Application Number
- CN202411984514.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-31
- Publication Date
- 2025-03-18
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Existing toothpastes have limited effects in solving oral inflammation such as gingivitis, periodontitis and oral ulcers, and the use of Chinese herbal extracts and essential oil extracts has problems with complex processes and insufficient anti-inflammatory and antibacterial ability.
By combining a variety of traditional Chinese medicine extracts and essential oil extracts with anti-inflammatory, antibacterial and analgesic functions, a gingival-protecting toothpaste is prepared, so that the paste penetrates deep into the gums and teeth nerves, achieving auxiliary treatment for symptoms such as gingival redness, periodontitis and oral ulcers.
It effectively improves and relieves discomfort symptoms such as gingival redness, inflammation, ulcers, inflammation of the teeth, loose teeth, periodontitis, pulpitis, toothache, cold and warmth sensitivity, and children's dental caries. It has the advantages of assisting in the treatment of toothache and gum diseases, and strengthening the foundation of the teeth.
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Figure BDA0005222252050000091
Abstract
Description
Technical Field
[0001] The invention relates to the field of new biology and medical technology, and in particular to a method for preparing a gum-protecting and tooth-strengthening toothpaste. Background Art
[0002] According to the functions, toothpastes on the market can be divided into two categories: one is ordinary toothpaste, which can only remove food residues and keep the mouth clean; the other is toothpaste with special functions, which has antibacterial or antibacterial, anti-inflammatory, whitening, descaling, anti-allergic, caries and periodontal disease prevention and treatment functions. With the development of new surfactants, special functional active ingredients, functional additives and other technologies, toothpaste has also been given many new functions, and has expanded from the initial requirement of brushing teeth to multi-functions.
[0003] However, in order to achieve different effects, a variety of chemical agents are often added to toothpaste. These ingredients will cause different side effects when used for a long time, and the effects of many existing functional toothpastes are still unsatisfactory. For example: users brush their teeth every morning and evening, and as time accumulates, dental plaque will still grow. Dental plaque is a soft and unmineralized bacterial group wrapped in a matrix that adheres to each other or to the tooth surface, between teeth, and the surface of restorations, and is associated with the occurrence of gingivitis, periodontitis, caries and other forms of periodontal disease. Dental plaque is cohesive and highly resistant to removal from the teeth and / or oral surfaces. The anaerobic bacteria in the plaque metabolize sugars to produce acids that dissolve tooth minerals, thereby damaging the tooth enamel and eventually forming caries.
[0004] Although most of the toothpastes on the market for oral inflammation are based on simple cleaning and fluoride anti-caries ingredients, they can temporarily clean teeth and mouth and solve caries problems, but they have limited effects on oral inflammation such as periodontitis, bleeding gums, and oral ulcers. Some toothpastes even add the Western medicine hemostatic ingredient tranexamic acid to treat bleeding gums.
[0005] Toothpaste's anti-plaque effect is mainly achieved through the pharmacological effects of anti-plaque drugs added to toothpaste. It is now recognized that certain drugs are added to toothpaste for the prevention of oral diseases such as gingivitis. Chinese herbal medicine is abundant in my country, many ancient prescriptions have certain efficacy, and their toxic side effects are significantly smaller than those of Western medicine. It also has a high acceptance among the people. Therefore, the use of Chinese herbal toothpaste to prevent oral diseases does have good prospects.
[0006] Although the existing patent CN108295023B discloses a method for preparing a Chinese herbal toothpaste with antibacterial, anti-inflammatory and gingival analgesic effects, its production process is relatively complicated and does not conform to the Chinese medicinal properties of some Chinese herbal extracts. For example, ethanol extraction of Galla chinensis and Ophiopogon japonicus is not suitable, and the anti-inflammatory and antibacterial capabilities of these Chinese herbal medicines are not strong. Therefore, how to use Chinese herbal extracts and essential oil extracts to prepare a toothpaste that can effectively improve gingival and tooth swelling and pain has become a technical problem to be solved urgently. Summary of the invention
[0007] In view of this, in order to overcome the above-mentioned shortcomings and deficiencies in the prior art, the present invention provides a method for preparing a gum protecting and teeth strengthening toothpaste, by combining a variety of Chinese medicine extracts and essential oil extracts with anti-inflammatory, antibacterial and analgesic functions, so that the prepared toothpaste paste penetrates deeply into the gums and dental nerves, achieving an obvious auxiliary treatment effect on symptoms such as gingival redness and swelling, periodontitis and oral ulcers, and effectively improving and relieving the discomfort symptoms such as gingival redness and swelling, inflammation, ulcers, dental nerve inflammation, loose teeth, periodontitis, pulpitis, toothache, sensitivity to cold and heat, and children's caries.
[0008] In order to achieve the above object, the present invention provides the following technical solutions:
[0009] The present invention provides a method for preparing a gum protecting and teeth strengthening ointment, comprising the following preparation steps:
[0010] 1) Weigh the raw materials according to the proportion and divide them into phase A, phase B, phase C, phase D and phase E;
[0011] Phase A includes calcium carbonate, hydrated silica, menthane carboxamide, detergent components and water; Phase B includes sorbitol, sodium lauryl sulfate, sodium benzoate and tetrasodium pyrophosphate; Phase C includes polyethylene glycol-8, sodium saccharin, butylated hydroxytoluene, sodium hydroxide and sodium bicarbonate; Phase D includes cellulose gum and guar gum; Phase E includes traditional Chinese medicine components, essential oil components, sodium hydroxide and butylated hydroxytoluene;
[0012] The cleaning agent components include blue salt and zeolite powder; the Chinese medicine components include cloves, myrrh, frankincense, eucalyptus leaves, sage, angelica dahurica, aconite root, wild soybean seeds and peppermint; the essential oil component includes red pine oil;
[0013] 2) mixing the phase A and deionized water to obtain a phase A solution; mixing the phase C and the phase D to obtain a pre-dispersed phase;
[0014] 3) Add the phase A solution and the phase B into a paste-making container, stir until they are evenly dispersed, and obtain a mixed raw material 1;
[0015] 4) mixing the mixed raw material 1 and the pre-dispersed phase, and stirring until the colloid is dispersed and hydrated completely to obtain the mixed raw material 2;
[0016] 5) After mixing phase E and the mixed raw material 2, stirring and degassing, the gum protecting and teeth strengthening toothpaste is obtained.
[0017] Preferably, the weight ratio of the blue salt to the zeolite powder in the cleaning agent is 3-5:1-2.
[0018] Preferably, the weight ratio of the calcium carbonate, hydrated silica, menthanecarboxamide and detergent component is 8-12:8-12:0.01-0.06.
[0019] Preferably, the weight ratio of polyethylene glycol-8, sodium saccharin, butylated hydroxytoluene, sodium hydroxide and sodium bicarbonate is 1-5:0.10-0.15:0.05-0.1:0.01-0.05:1-1.6.
[0020] Preferably, the weight ratio of the traditional Chinese medicine component to the essential oil component is 0.81-0.90:0.8-0.12.
[0021] Preferably, the weight ratio of clove, myrrh, frankincense, eucalyptus leaves, sage, angelica dahurica, aconite root, wild soybean seeds and peppermint in the traditional Chinese medicine components is 0.4-0.6:0.4-0.6:0.8-1.0:0.4-0.6:0.4-0.6:0.4-0.6:0.01-0.15:0.1-0.2:0.4-0.6.
[0022] Preferably, the stirring and degassing in step 5) are both performed under vacuum conditions.
[0023] Preferably, the weight ratio of phase A, phase B, phase C, phase D and phase E is 46.10-47.10:38.4-39.5:4.4-5.2:4.45-5.25.
[0024] The present invention also provides the use of the gum protecting and teeth strengthening toothpaste prepared according to the preparation method in improving periodontitis and gingival swelling and pain.
[0025] The present invention adopts the traditional Chinese medicine formula idea, fully applies the principle of monarch, minister, assistant and envoy, and combines the characteristics of good penetration and fast effect of modern essential oils, and innovatively proposes a method of combining a variety of Chinese medicine extracts and essential oil extracts with anti-inflammatory, antibacterial and analgesic functions, so that the prepared toothpaste paste can penetrate deeply into the gums and teeth and dental nerves, and achieves obvious auxiliary treatment effects on symptoms such as gingival swelling, periodontitis and oral ulcers, effectively improves and relieves the uncomfortable symptoms of gingival swelling, inflammation, ulcers, dental nerve inflammation, loose teeth, periodontitis, pulpitis, toothache, cold and heat sensitivity, children's caries, etc., has the advantages of significant auxiliary treatment of diseases such as toothache and gums, and strengthening the foundation of teeth.
[0026] Compared with the prior art, the present invention has the following beneficial effects:
[0027] The present invention utilizes the synergistic effect of Chinese herbal medicine and essential oil, so that Chinese herbal medicines such as isatis salt and cyperus root powder can penetrate into gums and dental nerves under the penetration of essential oil, thereby achieving the effect of nourishing cementum, enamel and dentin; at the same time, the present invention achieves the effects of promoting blood circulation, removing blood stasis, relieving pain and reducing inflammation by infiltrating frankincense and myrrh essential oil extracts into gums.
[0028] The invention improves the mouth feel of the toothpaste by adding a trace amount of sodium saccharin, peppermint oil and the like, making the mouth feel more suitable for the taste of the general public, especially children have a good acceptance of the product, can be used for a long time, is safe and has no toxic side effects, and can effectively solve a variety of oral inflammation problems, such as gingivitis, oral ulcers, halitosis and the like.
[0029] The present invention achieves the effects of relieving fever, swelling, pain and relieving anesthesia of dental nerves by adding angelica dahurica and clove essential oil extracts to the raw materials. At the same time, the European red pine oil extract added in the present invention can resist bacteria and inflammation and promote blood circulation in gums; eucalyptus essential oil directly acts on toothache and helps to quickly achieve the effect of regulating qi and relieving pain; rat tail essential oil achieves the effects of reducing inflammation, treating sores, promoting cell regeneration and repairing gum cells, and the roasted aconite can play a role in strengthening teeth. DETAILED DESCRIPTION
[0030] The present invention provides a method for preparing a gum protecting and teeth strengthening toothpaste, comprising the following preparation steps:
[0031] 1) Weigh the raw materials according to the proportion and divide them into phase A, phase B, phase C, phase D and phase E;
[0032] Phase A includes calcium carbonate, hydrated silica, menthane carboxamide, detergent components and water; Phase B includes sorbitol, sodium lauryl sulfate, sodium benzoate and tetrasodium pyrophosphate; Phase C includes polyethylene glycol-8, sodium saccharin, butylated hydroxytoluene, sodium hydroxide and sodium bicarbonate; Phase D includes cellulose gum and guar gum; Phase E includes traditional Chinese medicine components, essential oil components, sodium hydroxide and butylated hydroxytoluene;
[0033] The cleaning agent components include blue salt and zeolite powder; the Chinese medicine components include cloves, myrrh, frankincense, eucalyptus leaves, sage, angelica dahurica, aconite root, wild soybean seeds and peppermint; the essential oil component includes red pine oil;
[0034] 2) mixing the phase A and deionized water to obtain a phase A solution; mixing the phase C and the phase D to obtain a pre-dispersed phase;
[0035] 3) Add the phase A solution and the phase B into a paste-making container, stir until they are evenly dispersed, and obtain a mixed raw material 1;
[0036] 4) mixing the mixed raw material 1 and the pre-dispersed phase, and stirring until the colloid is dispersed and hydrated completely to obtain the mixed raw material 2;
[0037] 5) After mixing phase E and the mixed raw material 2, stirring and degassing, the gum protecting and teeth strengthening toothpaste is obtained.
[0038] In the present invention, the weight ratio of the isotretinoin and the zeolite powder in the detergent is preferably 3-5; 1-2, more preferably 5:2; the weight ratio of the calcium carbonate, hydrated silica, menthanecarboxamide and detergent components is preferably 8-12:8-12:0.01-0.06, more preferably 10:10:0.05; the weight ratio of polyethylene glycol-8, sodium saccharin, butylated hydroxytoluene, sodium hydroxide and sodium bicarbonate is preferably 1-5:0.10-0.15:0.05-0.1:0.01-0.05:1-1.6, more preferably 3:0.15:0.1:0.05:1.5.
[0039] In the present invention, the weight ratio of the traditional Chinese medicine component to the essential oil component is preferably 0.81-0.90:0.8-0.12, more preferably 0.87:0.1; the weight ratio of clove, myrrh, frankincense, eucalyptus leaves, sage, angelica dahurica, aconite, wild soybean seeds and peppermint in the traditional Chinese medicine component is preferably 0.4-0.6:0.4-0.6:0.8-1.0:0.4-0.6:0.4-0.6:0.4-0.6: 0.01-0.15:0.1-0.2:0.4-0.6, more preferably 0.5:0.5:1:0.5:0.5:0.5:0.15:0.2:0.5; the weight ratio of phase A, phase B, phase C, phase D and phase E is preferably 46.10-47.10:38.4-39.5:4.4-5.2:4.45-5.25, more preferably 46.55:38.9:4.8:4.85.
[0040] The present invention utilizes the synergistic effect of Chinese herbal medicine and essential oil, so that Chinese herbal medicines such as green salt and cyperus root powder can penetrate into gums and dental nerves under the penetration of essential oil, thereby achieving the effect of nourishing cementum, enamel and dentin; at the same time, the present invention achieves the effects of promoting blood circulation, removing blood stasis, relieving pain and reducing inflammation in a manner in which frankincense and myrrh essential oil extracts penetrate into the gums.
[0041] The invention improves the mouth feel of the toothpaste by adding trace amounts of sodium saccharin, peppermint oil, etc., so that the taste is more suitable for the taste of the general public, especially children have a good acceptance of the product, can be used for a long time, is safe and has no toxic side effects, and can effectively solve a variety of oral inflammation problems, such as gingivitis, oral ulcers, halitosis, etc.
[0042] The invention achieves the effects of relieving fever, swelling, pain, and soothing and anesthetizing tooth nerves by adding angelica dahurica and clove essential oil extracts into the raw materials.
[0043] In the present invention, the European red pine oil extract can be antibacterial and anti-inflammatory, and promote blood circulation in the gums; the eucalyptus essential oil can regulate qi and relieve pain, and directly act on toothache; the rat tail essential oil can reduce inflammation, treat sores, promote cell regeneration, and repair gum cells, and the roasted aconite can play a role in strengthening teeth.
[0044] The present invention adopts the traditional Chinese medicine formula idea, fully applies the monarch, minister, assistant and envoy principle, and combines the characteristics of good penetration and fast effect of modern essential oils, and innovatively proposes a preparation method of combining a variety of Chinese medicine extracts and essential oil extracts with anti-inflammatory, antibacterial and analgesic functions, so that the prepared toothpaste paste penetrates deeply into the gums and teeth and dental nerves, and achieves obvious auxiliary treatment effects on symptoms such as gingival swelling, periodontitis and oral ulcers, effectively improves and relieves the uncomfortable symptoms of gingival swelling, inflammation, ulcers, dental nerve inflammation, loose teeth, periodontitis, pulpitis, toothache, sensitivity to cold and heat, children's caries, etc., has the advantages of significant auxiliary treatment of diseases such as toothache and gums, and strengthening the foundation of teeth.
[0045] In order to better understand the present invention, the content of the present invention is further explained below in conjunction with the embodiments, but the content of the present invention is not limited to the following embodiments.
[0046] Example 1
[0047] The raw materials used in the toothpaste described in this embodiment are composed of the following ingredients by weight percentage: 10% calcium carbonate, 24% water, 38% sorbitol, 10% hydrated silica, 83% polyethylene glycol, 0.5% sodium lauryl sulfate, 2% zeolite powder, 5% blue salt, 0.5% eucalyptus globulus leaf oil, 0.5% sage, 0.5% angelica dahurica, 0.5% clove, 0.5% myrrh, 0.5% Scots pine leaf oil, 0.5% peppermint oil, 0.2% wild soybean seeds, 0.15% aconite, 0.2% cellulose gum, 0.2% guar gum, 0.2% sodium benzoate, 0.2% tetrasodium pyrophosphate, 0.15% saccharin sodium, 0.1% butylated hydroxytoluene, 0.05% sodium hydroxide, 0.05% menthanecarboxamide, 1% frankincense, and 1.5% sodium bicarbonate.
[0048] The preparation method of the gum protecting and teeth strengthening toothpaste in this embodiment comprises the following steps:
[0049] 1) Weigh the raw materials in a ratio of 46.55:38.9:4.8:4.85 and divide them into phase A, phase B, phase C, phase D, and phase E;
[0050] Phase A includes calcium carbonate, hydrated silica, menthane carboxamide, detergent components and water; Phase B includes sorbitol, sodium lauryl sulfate, sodium benzoate and tetrasodium pyrophosphate; Phase C includes polyethylene glycol-8, sodium saccharin, butylated hydroxytoluene, sodium hydroxide and sodium bicarbonate; Phase D includes cellulose gum and guar gum; Phase E includes traditional Chinese medicine components, essential oil components, sodium hydroxide and butylated hydroxytoluene;
[0051] The cleaning agent components include blue salt and zeolite powder; the Chinese medicine components include cloves, myrrh, frankincense, eucalyptus leaves, sage, angelica dahurica, aconite root, wild soybean seeds and peppermint; the essential oil component includes red pine oil;
[0052] 2) mixing the phase A and deionized water to obtain a phase A solution; mixing the phase C and the phase D to obtain a pre-dispersed phase;
[0053] 3) Add the phase A solution and the phase B into a paste-making container, stir until they are evenly dispersed, and obtain a mixed raw material 1;
[0054] 4) mixing the mixed raw material 1 and the pre-dispersed phase, and stirring until the colloid is dispersed and hydrated completely to obtain the mixed raw material 2;
[0055] 5) After mixing phase E and the mixed raw material 2, stirring and degassing, the gum protecting and teeth strengthening toothpaste is obtained.
[0056] Example 2
[0057] The raw materials used in the toothpaste described in this embodiment are composed of the following ingredients by weight percentage: 10% calcium carbonate, 24% water, 38% sorbitol, 10% hydrated silica, 84% polyethylene glycol, 0.5% sodium lauryl sulfate, 2% zeolite powder, 3% blue salt, 0.6% eucalyptus leaf oil, 0.6% sage, 0.6% angelica, 0.6% clove, 0.6% myrrh, 0.6% Scots pine leaf oil, 0.6% peppermint oil, 0.1% wild soybean seeds, 0.15% aconite, 0.2% cellulose gum, 0.2% guar gum, 0.2% sodium benzoate, 0.2% tetrasodium pyrophosphate, 0.15% saccharin sodium, 0.15% butylated hydroxytoluene, 0.06% sodium hydroxide, 0.05% menthanecarboxamide, 1% frankincense, and 1.5% sodium bicarbonate.
[0058] The preparation method of the gum protecting and teeth strengthening toothpaste in this embodiment comprises the following steps:
[0059] 1) Weigh the raw materials according to the above ratios and divide them into phase A, phase B, phase C, phase D, and phase E;
[0060] Phase A includes calcium carbonate, hydrated silica, menthane carboxamide, detergent components and water; Phase B includes sorbitol, sodium lauryl sulfate, sodium benzoate and tetrasodium pyrophosphate; Phase C includes polyethylene glycol-8, sodium saccharin, butylated hydroxytoluene, sodium hydroxide and sodium bicarbonate; Phase D includes cellulose gum and guar gum; Phase E includes traditional Chinese medicine components, essential oil components, sodium hydroxide and butylated hydroxytoluene;
[0061] The cleaning agent components include blue salt and zeolite powder; the Chinese medicine components include cloves, myrrh, frankincense, eucalyptus leaves, sage, angelica dahurica, aconite root, wild soybean seeds and peppermint; the essential oil component includes red pine oil;
[0062] 2) mixing the phase A and deionized water to obtain a phase A solution; mixing the phase C and the phase D to obtain a pre-dispersed phase;
[0063] 3) Add the phase A solution and the phase B into a paste-making container, stir until they are evenly dispersed, and obtain a mixed raw material 1;
[0064] 4) mixing the mixed raw material 1 and the pre-dispersed phase, and stirring until the colloid is dispersed and hydrated completely to obtain the mixed raw material 2;
[0065] 5) After mixing phase E and the mixed raw material 2, stirring and degassing, the gum protecting and teeth strengthening toothpaste is obtained.
[0066] Example 3
[0067] The raw materials used in the toothpaste described in this embodiment are composed of the following ingredients by weight percentage: 10% calcium carbonate, 24% water, 40% sorbitol, 10% hydrated silica, 83% polyethylene glycol, 0.5% sodium lauryl sulfate, 1% zeolite powder, 4% blue salt, 0.4% eucalyptus globulus leaf oil, 0.4% sage, 0.4% angelica dahurica, 0.4% clove, 0.4% myrrh, 0.4% Scots pine leaf oil, 0.4% peppermint oil, 0.2% wild soybean seeds, 0.15% aconite, 0.2% cellulose gum, 0.2% guar gum, 0.2% sodium benzoate, 0.2% tetrasodium pyrophosphate, 0.15% saccharin sodium, 0.1% butylated hydroxytoluene, 0.05% sodium hydroxide, 0.05% menthanecarboxamide, 1% frankincense, and 1.5% sodium bicarbonate.
[0068] The preparation method of the gum protecting and teeth strengthening toothpaste in this embodiment comprises the following steps:
[0069] 1) Weigh the raw materials according to the above ratios and divide them into phase A, phase B, phase C, phase D, and phase E;
[0070] Phase A includes calcium carbonate, hydrated silica, menthane carboxamide, detergent components and water; Phase B includes sorbitol, sodium lauryl sulfate, sodium benzoate and tetrasodium pyrophosphate; Phase C includes polyethylene glycol-8, sodium saccharin, butylated hydroxytoluene, sodium hydroxide and sodium bicarbonate; Phase D includes cellulose gum and guar gum; Phase E includes traditional Chinese medicine components, essential oil components, sodium hydroxide and butylated hydroxytoluene;
[0071] The cleaning agent components include blue salt and zeolite powder; the Chinese medicine components include cloves, myrrh, frankincense, eucalyptus leaves, sage, angelica dahurica, aconite root, wild soybean seeds and peppermint; the essential oil component includes red pine oil;
[0072] 2) mixing the phase A and deionized water to obtain a phase A solution; mixing the phase C and the phase D to obtain a pre-dispersed phase;
[0073] 3) Add the phase A solution and the phase B into a paste-making container, stir until they are evenly dispersed, and obtain a mixed raw material 1;
[0074] 4) mixing the mixed raw material 1 and the pre-dispersed phase, and stirring until the colloid is dispersed and hydrated completely to obtain the mixed raw material 2;
[0075] 5) After mixing phase E and the mixed raw material 2, stirring and degassing, the gum protecting and teeth strengthening toothpaste is obtained.
[0076] Comparative Example 1
[0077] The raw materials of this comparative example do not contain Chinese herbal medicines such as frankincense, angelica dahurica and sage, and the remaining operation steps are the same as those in Example 1.
[0078] Comparative Example 2
[0079] In this comparative example, the essential oil extract European red pine oil was not used as the raw material, and the remaining operation steps were the same as those in Example 2.
[0080] Comparative Example 3
[0081] No blue salt or roasted aconite root was added to the raw materials of this comparative example, and the remaining operating steps were the same as those in Example 3.
[0082] Performance Testing
[0083] 1. Antibacterial property test of toothpaste: With reference to the antibacterial effect test method (suspension quantitative method) of antibacterial daily chemical products in QB / T 2738-2012 "Evaluation method for antibacterial and antibacterial effect of daily chemical products", the antibacterial rates of the toothpastes described in Examples 1-3 and Comparative Examples 1-3 against Porphyromonas gingivalis, Staphylococcus aureus, and Candida albicans were tested. The specific results are shown in Table 1.
[0084] Table 1
[0085]
[0086] It can be seen from the above table that compared with Examples 1-3, the toothpaste prepared in Comparative Examples 1-3 has a lower antibacterial rate against Porphyromonas gingivalis, Staphylococcus aureus, Candida albicans, etc., which further illustrates that the toothpaste prepared by the present invention has an obvious auxiliary therapeutic effect on symptoms such as gingival redness and swelling, periodontitis and oral ulcers, has a significant auxiliary treatment effect on toothache and gum disease, and has the advantage of strengthening the foundation of teeth.
[0087] 2. Toothpaste treatment of periodontitis;
[0088] The present invention tested the periodontitis treatment effect of the toothpaste prepared by the present invention on 30 volunteer subjects. The test period was 45 days, the toothpaste was used twice a day, and the disease progression of the volunteer subjects was observed and recorded every day.
[0089] According to the records, in subjects with gingivitis, significant improvement of inflammation was observed from 3-4 days after the start of treatment, and the inflammation was basically healed from the 5th to 7th day; in subjects with recurrent periodontal disease, no recurrence was observed in the subjects during the 3-month observation period after daily use of the toothpaste containing the present invention. It can be seen that the toothpaste prepared by the present invention can effectively improve and relieve the symptoms of red and swollen gums, inflammation, ulcers, periodontitis, pulpitis, etc., and has the advantages of significantly assisting in the treatment of toothache and gum diseases, and strengthening the foundation of teeth.
[0090] In summary, the present invention innovatively proposes a preparation method of combining a variety of traditional Chinese medicine extracts and essential oil extracts with anti-inflammatory, antibacterial and analgesic functions, so that the prepared toothpaste paste penetrates deeply into the gums and dental nerves of the teeth, achieving an obvious auxiliary treatment effect on symptoms such as gingival redness and swelling, periodontitis and oral ulcers, and effectively improves and alleviates the discomfort symptoms of gingival redness and swelling, inflammation, ulcers, dental nerve inflammation, loose teeth, periodontitis, pulpitis, toothache, sensitivity to cold and heat, children's caries, etc., and has the advantages of significantly assisting the treatment of diseases such as toothache and gums, and strengthening the foundation of teeth.
[0091] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.
Claims
1. A method for preparing a gum-protecting and tooth-strengthening toothpaste, characterized in that: The method comprises the following preparation steps: 1) Weigh the raw materials according to the proportion and divide them into phase A, phase B, phase C, phase D and phase E; Phase A includes calcium carbonate, hydrated silica, menthane carboxamide, detergent components and water; Phase B includes sorbitol, sodium lauryl sulfate, sodium benzoate and tetrasodium pyrophosphate; Phase C includes polyethylene glycol-8, sodium saccharin, butylated hydroxytoluene, sodium hydroxide and sodium bicarbonate; Phase D includes cellulose gum and guar gum; Phase E includes traditional Chinese medicine components, essential oil components, sodium hydroxide and butylated hydroxytoluene; The cleaning agent components include blue salt and zeolite powder; the Chinese medicine components include cloves, myrrh, frankincense, eucalyptus leaves, sage, angelica dahurica, aconite root, wild soybean seeds and peppermint; the essential oil component includes red pine oil; 2) mixing the phase A and deionized water to obtain a phase A solution; mixing the phase C and the phase D to obtain a pre-dispersed phase; 3) Add the phase A solution and the phase B into a paste-making container, stir until they are evenly dispersed, and obtain a mixed raw material 1; 4) mixing the mixed raw material 1 and the pre-dispersed phase, and stirring until the colloid is dispersed and hydrated completely to obtain the mixed raw material 2; 5) After mixing phase E and the mixed raw material 2, stirring and degassing, the gum protecting and teeth strengthening toothpaste is obtained.
2. The preparation method according to claim 1, characterized in that: The weight ratio of the blue salt to the zeolite powder in the cleaning agent is 3-5:1-2.
3. The preparation method according to claim 2, characterized in that: The weight ratio of the calcium carbonate, hydrated silica, menthane carboxamide and detergent components is 8-12:8-12:0.01-0.
06.
4. The preparation method according to claim 2, characterized in that: The weight ratio of polyethylene glycol-8, sodium saccharin, butylated hydroxytoluene, sodium hydroxide and sodium bicarbonate is 1-5:0.10-0.15:0.05-0.1:0.01-0.05:1-1.
6.
5. The preparation method according to claim 1, characterized in that: The weight ratio of the traditional Chinese medicine component to the essential oil component is 0.81-0.90:0.8-0.
12.
6. The preparation method according to claim 1, characterized in that: The weight ratio of clove, myrrh, frankincense, eucalyptus leaves, sage, angelica dahurica, aconite root, wild soybean seeds and peppermint in the traditional Chinese medicine components is 0.4-0.6:0.4-0.6:0.8-1.0:0.4-0.6:0.4-0.6:0.4-0.6:0.01-0.15:0.1-0.2:0.4-0.
6.
7. The preparation method according to claim 1, characterized in that: The stirring and degassing in step 5) are both performed under vacuum conditions.
8. The preparation method according to claim 1, characterized in that: The weight ratio of the phase A, phase B, phase C, phase D and phase E is 46.10-47.10:38.4-39.5:4.4-5.2:4.45-5.
25.
9. Use of the gum protecting and teeth strengthening toothpaste prepared by the method according to any one of claims 1 to 7 in improving periodontitis and gingival swelling and pain.
Citation Information
Patent Citations
A Chinese herbal toothpaste and its preparation method
CN108295023B