Tumor electric field treatment system

Abstract

The invention provides a tumor electric field treatment system which comprises an electric field generator and a plurality of pairs of electrode plates electrically connected with the electric field generator, each electrode plate comprises an electrode array, and each electrode array comprises a trunk and a plurality of branches radially extending from the trunk to the periphery of the trunk. A plurality of electrode units and connecting parts for connecting two adjacent electrode units are arranged on the trunk; each branch is also provided with an electrode unit and a connecting part for connecting the electrode unit to the trunk, and each electrode unit positioned on the branch is only connected with the trunk through a corresponding connecting part; the electrode array also has an AC signal trace, a number of ground traces, and a number of signal traces. According to the tumor electric field treatment system, the number of the conductive traces on the electrode plates can be reduced, and the layout scheme of the conductive traces is simplified.

Description

Technical Field

[0001] The present application relates to the field of medical device technology, and in particular to a tumor electric field therapy system. Background Art

[0002] Tumor electric field therapy is a tumor treatment method that uses a special electric field generator to generate a low-intensity, medium-high frequency, alternating electric field to interfere with the mitotic process of tumor cells. Studies have shown that electric field therapy is effective in treating glioblastoma, non-small cell lung cancer, malignant pleural mesothelioma and other diseases. The electric field applied by this treatment method can affect the aggregation of microtubule proteins, prevent spindle formation, inhibit the mitotic process, and induce apoptosis of cancer cells. The tumor electric field treatment system mainly includes an electric field generator, an adapter, and multiple pairs of electrodes. The electric field generator generates an alternating electrical signal and transmits the alternating electrical signal to the electrode through the adapter. The electrode sheets are applied in pairs to the body surface on opposite sides of the patient's tumor area, and an alternating current signal is applied between each pair of electrodes to non-invasively apply the tumor treatment electric field to the tumor area.

[0003] During electric field therapy, the electrode sheet will gather heat at the application site, and the temperature will rise accordingly. Therefore, it is necessary to monitor the temperature at the application site. When the temperature is too high, the electric field strength needs to be adjusted in time to avoid the risk of the patient's skin being burned due to excessive temperature. The electrode sheet is usually provided with multiple electrode units. Even if the same alternating current signal is applied to each electrode unit, the heat generated on each electrode unit will be different due to its different position, that is, the temperature of each electrode unit on the electrode sheet will not be completely consistent. It may happen that the temperature of a certain electrode unit exceeds the temperature threshold while the temperature of other electrode units is normal. Therefore, it is necessary to set a temperature sensor on each electrode unit to detect the temperature of each electrode unit in order to effectively avoid the risk of burns caused by excessive temperature of a single electrode unit. The existing electrode sheet is a conductive trace for each electrode unit to transmit a temperature detection signal. When the number of electrode units is large, the number of conductive traces on the electrode sheet also increases accordingly, resulting in a more complicated wiring scheme and affecting the flexibility of the electrode sheet, resulting in poor application.

[0004] Therefore, it is necessary to provide an improved tumor electric field treatment system and electrode sheet to overcome the problems existing in the prior art. Summary of the invention

[0005] The present application provides a tumor electric field therapy system, which can simplify the layout of conductive traces on an electrode sheet.

[0006] Specifically, the present application is implemented through the following technical solutions: a tumor electric field treatment system, which includes an electric field generator and several pairs of electrode sheets electrically connected to the electric field generator, the electrode sheets include an electrode array, the electrode array includes a trunk and several branches radially extending from the trunk to the surrounding areas, the trunk is provided with several electrode units and a connecting portion connecting two adjacent electrode units; the branch is also provided with an electrode unit and a connecting portion connecting the electrode unit to the trunk, each of the electrode units located on the branch is connected to the trunk only through a corresponding connecting portion; the electrode array also has an AC signal trace for transmitting alternating current signals to each electrode unit, several ground traces for short-circuiting the ground ends of the corresponding electrode units to ground, and several signal traces for connecting the signal ends of the corresponding electrode units in parallel and cooperating with the ground traces to transmit the temperature detection signals of the corresponding electrode units in time-sharing.

[0007] According to one embodiment of the present invention, the electrode unit includes a plurality of central electrode units disposed on the trunk and a plurality of peripheral electrode units disposed on the branches, and each of the peripheral electrode units is connected only to the most adjacent central electrode unit through the corresponding connecting portion.

[0008] According to one embodiment of the present invention, the electrode units are divided into multiple rows and columns in terms of circuit connection, the ground ends of the electrode units in each row are connected to the same ground trace, the signal ends of the electrode units in each column are connected to the same signal trace, and the AC signal trace connects each electrode unit.

[0009] According to one embodiment of the present invention, the tumor electric field therapy system also includes an AC line, a plurality of grounding switches and a plurality of detection channels, the AC line is connected to the AC signal trace, the grounding trace is connected to the grounding switch in a one-to-one correspondence, and the signal trace is connected to the detection channel in a one-to-one correspondence; the detection channels are all turned on when collecting the temperature detection signal of the electrode unit, and the grounding switches are closed individually and in sequence when collecting the temperature detection signal of the electrode unit.

[0010] According to one embodiment of the present invention, each electrode unit is provided with a temperature sensor, and the temperature sensor is provided with a ground terminal and a signal terminal. The ground terminal of the temperature sensor is the ground terminal of the corresponding electrode unit, and the signal terminal of the temperature sensor is the signal terminal of the corresponding electrode unit.

[0011] According to one embodiment of the present invention, there are thirteen electrode units, and there are four ground traces, wherein each of the three ground traces is respectively connected to the ground ends of the three electrode units, and the other ground trace is connected to the ground ends of the remaining four electrode units; there are four signal traces, wherein each of the three signal traces is respectively connected to the signal ends of the four electrode units, and the other signal trace is only connected to the signal end of the remaining one electrode unit.

[0012] According to one embodiment of the present invention, the thirteen electrode units are spatially arranged into five rows and five columns, the first row and the fifth row each have two electrode units and are respectively located on the second column and the fourth column, and the middle three rows each have three electrode units and are respectively located on the first column, the third column and the fifth column; in terms of circuit connection, the ground ends of the two electrode units in the first row and any electrode unit in the fifth row are each connected to one ground trace; the ground ends of the three electrode units in the second row are each connected to one ground trace; the ground ends of the three electrode units in the third row are each connected to one ground trace; the ground ends of the three electrode units in the fourth row and the remaining electrode unit in the fifth row are each connected to one ground trace.

[0013] According to one embodiment of the present invention, in terms of circuit connection, the signal end of any one of the electrode units located in the fifth row is connected to one of the signal traces; the signal ends of the three electrode units located in the third column and the remaining one of the electrode units located in the fifth row are respectively connected to one of the signal traces; the signal ends of the three electrode units located in the first column and any one of the electrode units in the first row are respectively connected to one of the signal traces; the signal ends of the three electrode units located in the fifth column and the remaining one of the electrode units located in the first row are respectively connected to one of the signal traces.

[0014] According to one embodiment of the present invention, the electrode array is provided with a flexible substrate, and most of the ground traces and the signal traces are arranged on the back side of the substrate; each of the electrode units is provided with a conductive plate located on the front side of the substrate, and the AC signal trace is arranged on the front side of the substrate and connected to each of the conductive plates.

[0015] According to an embodiment of the present invention, part of the ground traces and / or part of the signal traces pass through the substrate to the front side of the substrate for jumpering, and then pass back to the back side of the substrate for further routing.

[0016] According to one embodiment of the present invention, the electrode array is provided with a wiring portion, and a plurality of gold fingers are respectively provided on the front and back sides of the wiring portion, and the ends of each ground trace pass through the wiring portion and are connected to the corresponding gold fingers located on the front side of the wiring portion, and the ends of each signal trace are connected to the corresponding gold fingers located on the back side of the wiring portion.

[0017] According to an embodiment of the present invention, the electrode unit is provided with a dielectric element electrically connected to the conductive disk.

[0018] According to an embodiment of the present invention, the electrode unit is provided with a diode connected in series between the ground terminal of the temperature sensor and the ground trace.

[0019] The tumor electric field therapy system of the present application adopts a temperature measurement method of obtaining the temperature value of each temperature sensor in batches, which can reduce the number of conductive traces on the electrode sheet and simplify the layout of the conductive traces on the electrode sheet.

[0020] It should be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 is a framework diagram of a tumor electric field treatment system according to one embodiment of the present application; Figure 2 A three-dimensional diagram of an electrode sheet of a tumor electric field treatment system according to the present application; Figure 3 for Figure 2 A partial exploded perspective view of the electrode sheet shown; Figure 4 for Figure 3 A plan view of the electrode array of the electrode sheet shown; Figure 5 for Figure 4 An exploded perspective view of the electrode array shown; Figure 6 for Figure 5 A wiring diagram of the front side of the substrate of the electrode array shown; Figure 7 for Figure 5 A wiring diagram of ground traces on the back side of the substrate of the electrode array shown; Figure 8 for Figure 5 A wiring diagram of signal traces on the back side of the substrate of the electrode array shown; Fig. 9 This is a schematic diagram of the circuit connection between an electrode and an adapter in a tumor electric field therapy system.

[0022] Description of reference numerals: Tumor electric field treatment system 100, electric field generator 10, adapter 20, controller 21, analog-to-digital conversion module 22, communication unit 23, voltage divider resistor 24, ground switch 25, power module 26, AC line 27, electrode sheet 30, electrode array 31, electrode unit 310, central electrode unit 310A, peripheral electrode unit 310B, connecting portion 311, wiring portion 312, gold finger 3121, substrate 313, main body 3131, connecting strip 3132, dielectric element 314, opening 3141, temperature sensor 315, ground terminal 3151, signal terminal 3152, support plate 3153 16. Conductive pad 3171, ground pad 3172, signal pad 3173, conductive trace 318, AC signal trace 318A, ground trace 318B, first ground trace 318B-1, second ground trace 318B-2, third ground trace 318B-3, fourth ground trace 318B-4, signal trace 318C, first signal trace 318C-1, second signal trace 318C-2, third signal trace 318C-3, fourth signal trace 318C-4, diode 319, backing 32, support member 33, through hole 331, adhesive member 34, connector 40. DETAILED DESCRIPTION

[0023] Here, exemplary embodiments will be described in detail, examples of which are shown in the accompanying drawings. When the following description refers to the drawings, unless otherwise indicated, the same numbers in different drawings represent the same or similar elements. The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with the present application. Instead, they are only examples of devices, systems, equipment and methods consistent with some aspects of the present application.

[0024] refer to Figure 1 As shown, the tumor electric field treatment system 100 includes an electric field generator 10, an adapter 20, and a plurality of electrode sheets 30 arranged in pairs, wherein the adapter 20 electrically connects the electric field generator 10 and each electrode sheet 30. The electric field generator 10 generates an alternating current signal required for treatment, and the adapter 20 receives the alternating current signal output from the electric field generator 10 and transmits the alternating current signal to the electrode sheet 30. The paired electrode sheets 30 are attached to the body surface of the patient corresponding to the tumor area, and the alternating current signal is applied to the patient's tumor area to interfere with or prevent the mitosis of the patient's tumor cells, thereby achieving the purpose of treating the tumor.

[0025] refer to Figure 2 and Figure 3As shown, the electrode sheet 30 includes an electrode array 31, a backing 32, a plurality of support members 33 and a plurality of adhesive members 34. The electrode array 31 is adhered to the backing 32 and electrically connected to the adapter 20 through a wire (not shown). The electrode array 31 is provided with thirteen electrode units 310 arranged in multiple rows and columns. The support member 33 is provided corresponding to each row of electrode units 310. The support member 33 is provided with a plurality of through holes 331 and is adhered to the backing 32 in a manner that the through holes 331 surround each electrode unit 310 in the corresponding row. The support member 33 can support and protect the electrode unit 310. The adhesive member 34 is also provided corresponding to each row of electrode units 310, covering each row of electrode units 310 and the corresponding support member 33. The electrode sheet 30 is applied to the patient's body surface in a manner that the exposed side of the adhesive member 34 faces the patient. Here, the side of the electrode sheet 30 facing the patient is defined as the front side, and the opposite side is defined as the back side. The backing 32 is a mesh non-woven fabric, and a biocompatible adhesive (not shown) is coated on the front side to closely adhere the backing 32 to the patient's body surface. The support member 33 is made of foam material. The adhesive member 34 has double-sided adhesiveness, preferably conductive gel, which can keep the skin surface moist and avoid causing skin problems.

[0026] refer to Figure 4 As shown, the thirteen electrode units 310 of the electrode array 31 are arranged in five rows and five columns in the spatial structure, the first row and the fifth row are each provided with two electrode units 310, and the middle three rows are each provided with three electrode units 310, wherein the electrode units 310 located in the middle three rows are arranged in three columns, respectively located in the first column, the third column and the fifth column of the electrode array 31, and the two electrode units 310 located in the first row and the fifth row are arranged in two columns, respectively located in the second column and the fourth column of the electrode array 31. The electrode unit 310 located in the middle of the electrode array 31 is defined as the central electrode unit 310A, which includes the three electrode units 310 located in the third column (also referred to as the central column) of the electrode array 31 and in the middle three rows thereof, and the other electrode units 310 are all located in the periphery of the electrode array 31, defined as the peripheral electrode units 310B, and all the peripheral electrode units 310B are arranged around all the central electrode units 310A.

[0027] The electrode array 31 also includes a plurality of connecting parts 311 connecting two adjacent electrode units 310. The arrangement of the connecting parts 311 structurally connects the electrode array 31 into a whole, and can also meet the wiring requirements of each electrode unit 310 to ensure that each electrode unit 310 can transmit the corresponding electrical signal. The connecting parts 311 make the electrode array 31 as a whole axially symmetrical fishbone-shaped arrangement, wherein the middle column is the symmetry axis of the electrode array 31, which is also its trunk, and the others are branches extending laterally from the trunk. That is, the three central electrode units 310A on the third column are connected to each other along the column direction, and each peripheral electrode unit 310B is only connected to the corresponding central electrode unit 310A closest to it along the row direction or oblique direction. With such an arrangement, the connecting parts 311 have less constraints on each peripheral electrode unit 310B, and each peripheral electrode unit 310B has a greater degree of freedom, which can avoid wrinkles around it when applied. In order to further increase the degree of freedom of each peripheral electrode unit 310B, the backing 32 can also be selectively grooved along the branches of the electrode array 31.

[0028] Specifically, the three central electrode units 310A are respectively located in the second row, the third row and the fourth row of the electrode array 31 and are all located in the third column, and are connected by corresponding connecting parts 311 along the column direction, and are located on the symmetry axis of the electrode array 31 to form the backbone of the electrode array 31; the peripheral electrode unit 310B located in the first row is connected to the central electrode unit 310A located in the second row through the corresponding connecting parts 311 extending in an oblique line, forming two branches that are respectively inclined upward, and the two branches are axially symmetrical about the symmetry axis of the electrode array 31; the peripheral electrode unit 310B located in the second row is connected to the central electrode unit 310A located in the second row through the corresponding connecting parts 311 arranged in the row direction, forming two branches that are respectively extended in the row direction, and the two branches are axially symmetrical about the symmetry axis of the electrode array 31; The peripheral electrode unit 310B in the third row is connected to the central electrode unit 310A in the third row through the corresponding connection part 311 arranged in the row direction, forming two branches extending in the row direction respectively, and the two branches are arranged in an axisymmetric shape with respect to the symmetry axis of the electrode array 31; the peripheral electrode unit 310B in the fourth row is also connected to the central electrode unit 310A in the fourth row through the corresponding connection part 311 arranged in the row direction, forming two branches extending in the row direction respectively, and the two branches are arranged in an axisymmetric shape with respect to the symmetry axis of the electrode array 31; the peripheral electrode unit 310B in the fifth row is connected to the central electrode unit 310A in the fourth row through the corresponding connection part 311 extending in an oblique line, forming two branches inclined downward respectively, and the two branches are arranged in an axisymmetric shape with respect to the symmetry axis of the electrode array 31. Each of the above peripheral electrode units 310B is connected to a corresponding central electrode unit 310A located on the trunk of the electrode array 31 through a corresponding connection part 311. Each branch is radially arranged around the trunk of the electrode array 31. In addition, the electrode array 31 is not provided with other redundant connecting parts 311. The electrode units 310 of the electrode array 31 are connected by the minimum number of connecting parts 311, and each peripheral electrode unit 310B is only connected to one corresponding central electrode unit 310A, and each peripheral electrode unit 310B is not connected to each other, thereby obtaining a greater degree of freedom, facilitating flexible movement during application, and avoiding wrinkles around it during application.

[0029] The electrode array 31 also includes a wiring portion 312, which is located on the symmetry axis of the electrode array 31 and extends outward from the central electrode unit 310A located in the fourth row along the column direction. A plurality of gold fingers 3121 are respectively provided on the front and back sides of the wiring portion 312 for electrical connection with a wire (not shown).

[0030] refer to Figure 5As shown, the electrode array 31 includes a substrate 313 in a sheet-like configuration from a hierarchical architecture. The substrate 313 is integrally arranged in each electrode unit 310, each connection portion 311 and the wiring portion 312 as a supporting bottom plate. Each electrode unit 310, each connection portion 311 and the wiring portion 312 is further provided with other structures on the front and / or bottom surface of the substrate 313, which will be described in detail later. The material of the substrate 313 is polyimide or polyester film, and has the characteristics of light weight, thin thickness, bendability, and high flexibility. For the convenience of description, the part of the substrate 313 corresponding to each electrode unit 310 is defined as the main body 3131, and the main body 3131 is circularly arranged. The part of the substrate 313 corresponding to each connection portion 311 and the wiring portion 312 is a connecting bar 3132, and each main body 3131 and each connecting bar 3132 are different parts of the entire substrate 313.

[0031] The electrode array 31 further includes a plurality of dielectric elements 314, which are arranged on the front of each main body 3131 in a one-to-one correspondence. The dielectric elements 314 are arranged in a circular ring shape, and an opening 3141 is arranged at the center thereof, and the opening 3141 exposes the front of the corresponding main body 3131. Each electrode unit 310 is provided with a temperature sensor 315, which is placed in the opening 3141 and fixed to the main body 3131, and then the temperature sensor 315 is further encapsulated in the opening 3141 of the dielectric element 314 by a sealant (not shown). In this embodiment, the dielectric element 314 is a ceramic sheet. The electrode array 31 further includes a plurality of support plates 316, which are arranged in a circular shape and are arranged on the back of each main body 3131 in a one-to-one correspondence, providing a support function and improving the strength of the electrode unit 310.

[0032] In this embodiment, the dielectric element 314 is a ceramic sheet. Optionally, the dielectric element 314 may also be in other forms, such as a polymer dielectric layer with a high dielectric constant and low dielectric loss made of a thin film material with non-fixed crystal orientation, high flexibility and high toughness. The polymer dielectric layer can be formed on the main body 3131 by evaporation, sputtering or ion plating vapor deposition, printing, spraying or casting; in addition, the support plate 316 is optionally provided.

[0033] refer to Figures 6 to 9As shown, the electrode array 31 is provided with a conductive pad 3171, a ground pad 3172 and a signal pad 3173 on the front of the main body 3131. The conductive pad 3171 is arranged in a ring shape, and the ground pad 3172 and the signal pad 3173 are located at the center of the conductive pad 3171 and are insulated from the conductive pad 3171. The dielectric element 314 is welded to the conductive pad 3171, and the temperature sensor 315 is provided with a ground terminal 3151 and a signal terminal 3152, wherein the ground terminal 3151 is welded to the ground pad 3172, and the signal terminal 3152 is welded to the signal pad 3173. The ground terminal 3151 of each temperature sensor 315 is the ground terminal of the corresponding electrode unit 310, and the signal terminal 3152 of each temperature sensor 315 is the signal terminal of the corresponding electrode unit 310.

[0034] refer to Figure 7 and Figure 8 As shown, a plurality of conductive traces 318 are arranged on the front and back of the substrate 313, wherein the conductive trace 318 located on the front of the substrate 313 is mainly an AC signal trace 318A, and a plurality of gold fingers 3121 of the connection portion 312 include a gold finger 3121 for transmitting an AC signal, and the AC signal trace 318A extends from the gold finger 3121 along the connection portion 312 and each connection portion 311 to each main body portion 3131 and is electrically connected to the conductive plate 3171 on each main body portion 3131, so as to transmit an AC signal to each electrode unit 310. Two parallel AC signal traces 318A are arranged on each connection portion 311 to ensure the stability of AC signal transmission.

[0035] Key References Figure 7 and Figure 8As shown, the plurality of conductive traces 318 located on the back side of the substrate 313 also include a plurality of ground traces 318B and a plurality of signal traces 318C. Each ground trace 318B is extended from a corresponding golden finger 3121 along the wiring portion 312 and the corresponding connecting portion 311 to the corresponding ground pads 3172 on the plurality of main body portions 3131, so as to be electrically connected to the ground terminal 3151 of the corresponding temperature sensor 315, and is used to ground the ground terminal (not shown) of the corresponding temperature sensor 315; each signal trace 318C is extended from a corresponding golden finger 3121 along the wiring portion 312 and the corresponding connecting portion 311 to the corresponding signal pads 3173 on one or more main body portions 3131, so as to be electrically connected to the signal terminal 3152 of the corresponding temperature sensor 315, and is used to transmit a direct current signal to the corresponding temperature sensor 315, so as to detect the temperature at the corresponding electrode unit 310, and transmit the detected temperature signal to the adapter 20 or the electric field generator 10. The substrate 313 is also provided with a diode 319 on each main body 3131, and the diode 319 is connected in series between the ground terminal 3151 of the temperature sensor 315 and the corresponding ground trace 318B. Specifically, the anode of the diode 319 is electrically connected to the ground terminal 3151 of the corresponding temperature sensor 315, and the cathode of the diode is electrically connected to the corresponding ground trace 318B. The main body 3131 is also provided with an anode pad (unnumbered) and a cathode pad (unnumbered) corresponding to the diode 319 at the center of the conductive disk 3171. The anode pad (unnumbered) is electrically connected to the ground pad 3172 through a corresponding pad trace (unnumbered). The diode 319 can prevent the reverse flow of current to prevent the detection signal from other electrode units 310 from affecting the temperature sensor 315.

[0036] In this embodiment, in order to obtain the temperature detection signals of the thirteen temperature sensors 315, four ground traces 318B and four signal traces 318C are provided on the substrate 313. The corresponding temperature sensors 315 in the multiple electrode units 310 can share the corresponding ground traces 318B and the corresponding signal traces 318C, and the temperature detection signals of each temperature sensor 315 are obtained in batches by grounding the ground traces 318B in turn. The control method is described in detail later. Compared with the method of setting an independent signal trace for each temperature sensor 315, this wiring method reduces the total number of conductive traces 318, reduces the wiring difficulty of the substrate 313, simplifies the manufacturing process of the electrode array 31, and can also improve the flexibility of the electrode array 31 and improve the fit during application. The wiring portion 312 is provided with ten gold fingers 3121, of which four gold fingers 3121 are respectively connected to four ground traces 318B in one-to-one correspondence; four gold fingers 3121 are respectively connected to four signal traces 318C in one-to-one correspondence, and one gold finger 3121 is connected to the AC signal trace 318A; one gold finger 3121 is connected to the shielding wire layer (not shown) of the conductive wire (not shown) and is grounded for electromagnetic shielding and preventing signal interference.

[0037] Continue to refer Figures 6 to 9 As shown, the wiring scheme of the ground trace 318B and the signal trace 318C will be specifically described below. In terms of spatial structure, the thirteen electrode units 310 are marked as electrode units M1-M13 from top to bottom and from left to right according to their positions. Specifically, the two electrode units 310 in the first row are electrode units M1 and M2; the three electrode units 310 in the second row are electrode units M3, M4, and M5; the three electrode units 310 in the third row are electrode units M6, M7, and M8; the three electrode units 310 in the fourth row are electrode units M9, M10, and M11; and the two electrode units 310 in the fifth row are electrode units M12 and M13. The four ground traces 318B are respectively a first ground trace 318B-1, a second ground trace 318B-2, a third ground trace 318B-3 and a fourth ground trace 318B-4; the four signal traces 318C are respectively a first signal trace 318C-1, a second signal trace 318C-2, a third signal trace 318C-3 and a fourth signal trace 318C-4.

[0038] Key References Figure 7 As shown, from the back side of the substrate 313, the wiring scheme of the four ground traces 318B is: The grounding terminals 3151 of the temperature sensors 315 of the electrode units M1, M2, and M13 are short-circuited in parallel to the first grounding trace 318B-1. The three electrode units 310 are located at the two end edges of the electrode sheet 30 in terms of spatial structure, and are all peripheral electrode units 310B. The specific routing method of the first grounding trace 318B-1 is as follows: it extends upward from the wiring portion 312 and is divided into two branches near the electrode unit M10. One branch passes through the corresponding connection portion 311 and the temperature sensor 315 of the electrode unit M13. The ground terminal 3151 of the temperature sensor 315 of the electrode unit M1 is connected to the ground pad 3172 corresponding to the ground terminal 3151 of the temperature sensor 315; the other branch passes through the electrode units M10, M7, M4 and the corresponding connecting part 311 in sequence and then divides into two branches that continue to extend upward, one of which passes through the corresponding connecting part 311 and is connected to the ground pad 3172 corresponding to the ground terminal 3151 of the temperature sensor 315 of the electrode unit M1, and the other branch passes through the corresponding connecting part 311 and is connected to the ground pad 3172 corresponding to the ground terminal 3151 of the temperature sensor 315 of the electrode unit M2.

[0039] The grounding terminals 3151 of the temperature sensors 315 of the electrode units M3, M4, and M5 are short-circuited in parallel to the second grounding trace 318B-2. The three electrode units 310 are located in the second row of the electrode sheet 30 in terms of spatial structure and are adjacent to each other. The specific routing method of the second grounding trace 318B-2 is as follows: it extends upward from the wiring portion 312 and passes through the electrode units M10, M7, M4 and the corresponding connecting portion 311 in sequence, and then connects to the grounding pad 3172 corresponding to the grounding terminal 3151 of the temperature sensor 315 of the electrode unit M4, and at the same time, it is divided into two branches to the left and right sides, one of which is connected to the grounding pad 3172 corresponding to the grounding terminal 3151 of the temperature sensor 315 of the electrode unit M3 through the corresponding connecting portion 311, and the other is connected to the grounding pad 3172 corresponding to the grounding terminal 3151 of the temperature sensor 315 of the electrode unit M5 through the corresponding connecting portion 311.

[0040] The grounding terminals 3151 of the temperature sensors 315 of the electrode units M6, M7, and M8 are short-circuited in parallel to the third grounding trace 318B-3. The three electrode units 310 are located in the third row of the electrode sheet 30 in terms of spatial structure and are adjacent to each other. The specific routing method of the third grounding trace 318B-3 is as follows: it extends upward from the wiring portion 312 and passes through the electrode units M10, M7 and the corresponding connecting portion 311 in sequence, and then connects to the grounding pad 3172 corresponding to the grounding terminal 3151 of the temperature sensor 315 of the electrode unit M7, and at the same time, it is divided into two branches to the left and right sides, one of which is connected to the grounding pad 3172 corresponding to the grounding terminal 3151 of the temperature sensor 315 of the electrode unit M6 through the corresponding connecting portion 311, and the other is connected to the grounding pad 3172 corresponding to the grounding terminal 3151 of the temperature sensor 315 of the electrode unit M8 through the corresponding connecting portion 311.

[0041] The grounding terminals 3151 of the temperature sensors 315 of the electrode units M9, M10, M11, and M12 are short-circuited in parallel to the fourth grounding trace 318B-4. The four electrode units 310 are located in the fourth row and the adjacent fifth row of the electrode sheet 30 in terms of spatial structure and are adjacent to each other. The specific routing method of the fourth ground trace 318B-4 is as follows: it extends upward from the wiring portion 312 and is divided into two branches near the electrode unit M10, one of which is connected to the ground pad 3172 corresponding to the ground terminal 3151 of the temperature sensor 315 of the electrode unit M12 through the corresponding connection portion 311, and the other branch continues to extend and is connected to the ground pad 3172 corresponding to the ground terminal 3151 of the temperature sensor 315 of the electrode unit M10, and then is divided into two branches to the left and right sides respectively, one of which is connected to the ground pad 3172 corresponding to the ground terminal 3151 of the temperature sensor 315 of the electrode unit M9 through the corresponding connection portion 311, and the other branch is connected to the ground pad 3172 corresponding to the ground terminal 3151 of the temperature sensor 315 of the electrode unit M11 through the corresponding connection portion 311.

[0042] The ends of the four ground traces 318B located on the wiring portion 312 all penetrate the corresponding parts of the wiring portion 312 and are respectively connected to the four corresponding gold fingers 3121 provided on the front of the wiring portion 312. When the electrode unit 310 is provided with diodes 319 corresponding to each temperature sensor 315, the corresponding ground traces 318B need to be electrically connected to the ground pad 3172 corresponding to the ground terminal 3151 of the corresponding temperature sensor 315 through the corresponding diode 319 and the anode pad (unnumbered) and cathode pad (unnumbered) corresponding to the diode 319.

[0043] Key References Figure 8 As shown, from the back side of the substrate 313, the wiring scheme of the four signal traces 318C is: The signal end 3152 of the temperature sensor 315 of the electrode unit M12 is connected to the first signal trace 318C-1; the specific routing method of the first signal trace 318C-1 is: extending upward from the wiring part 312 and then passing through the corresponding connecting part 311 to connect with the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M12.

[0044] The signal terminals 3152 of the temperature sensors 315 of the electrode units M1, M3, M6, and M9 are connected in parallel to the second signal trace 318C-2. The four electrode units 310 are all located on the left side of the symmetry axis of the electrode array 31 in terms of spatial structure ( Figure 8on the right side); the specific routing method of the second signal trace 318C-2 is as follows: it extends upward from the wiring portion 312, passes through the electrode units M10, M9 and the corresponding connection portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M9, then returns and passes through the electrode units M10, M7, M6 and the corresponding connection portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M6, then returns and passes through the electrode units M7, M4, M3 and the corresponding connection portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M3, and finally returns and passes through the electrode unit M4 and the corresponding connection portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M1, without any branches in the middle.

[0045] The signal terminals 3152 of the temperature sensors 315 of the electrode units M2, M5, M8, and M11 are connected in parallel to the third signal trace 318C-3. The four electrode units 310 are all located on the right side of the symmetry axis of the electrode array 31 in terms of spatial structure ( Figure 8 on the left side); the specific routing method of the third signal trace 318C-3 is as follows: it extends upward from the wiring portion 312, passes through the electrode units M10, M11 and the corresponding connecting portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M11, then returns and passes through the electrode units M10, M7, M8 and the corresponding connecting portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M8, then returns and passes through the electrode units M7, M4, M5 and the corresponding connecting portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M5, and finally returns and passes through the electrode unit M4 and the corresponding connecting portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M2, without any branches in the middle.

[0046] The signal end 3152 of the temperature sensor 315 of each of the electrode units M4, M7, M10, and M13 is connected in parallel to the fourth signal trace 318C-4. In terms of spatial structure, three of the four electrode units 310 are located on the symmetry axis of the electrode array 31, and the other is close to the symmetry axis. The specific routing method of the fourth signal trace 318C-4 is as follows: it is divided into two branches at the connection portion 312, one branch extends upward along the symmetry axis, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode units M10, M7, and M4 in sequence when passing through the electrode units M10, M7, and M4 and the corresponding connection portion 311, and the other branch is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M13 through the corresponding connection portion 311.

[0047] The ends of the four signal traces 318C on the connection portion 312 are respectively connected to four corresponding gold fingers 3121 disposed on the back side of the connection portion 312 in a one-to-one correspondence.

[0048] It is understandable that although the ground traces 318B and the signal traces 318C are mostly arranged on the back side of the substrate 313, the ground traces 318B need to pass through the corresponding parts of the substrate 313 and be electrically connected to the corresponding ground pads 3172 on the front side of the substrate 313. In addition, the four ground traces 318B and the four signal traces 318C are arranged in parallel on the back side of the substrate 313 without interfering with each other, but the ground traces 318B and the signal traces 318C will inevitably cross in some places on the substrate 313 due to wiring requirements. In order to avoid interference, the ground traces 318B or the signal traces 318C at the intersection will pass through the corresponding parts of the substrate 313 to the front side of the substrate 313 for jumpering, and then pass back to the back side of the substrate 313 to continue to be arranged. Therefore, there are also shorter portions of the ground trace 318B and the signal trace 318C on the front side of the substrate 313 , and the portions of the ground trace 318B and the signal trace 318C on the front side of the substrate 313 and the AC signal trace 318A do not interfere with each other.

[0049] Combine the following Fig. 9As shown, the temperature measurement and control method of the electrode sheet 30 of the present application is described in detail. The wire (not shown) of the electrode sheet 30 is plugged into the connector 40 of the adapter 20 to realize the circuit connection between the electrode sheet 30 and the adapter 20. In terms of circuit arrangement, thirteen electrode units 310 are arranged on the substrate 313 in the form of a two-dimensional array, in four rows and four columns. Specifically, the first row has three electrode units 310, namely electrode units M1, M2, and M13, and these three electrode units 310 are located in the second to fourth columns; the second row has three electrode units 310, namely electrode units M3, M5, and M4, and these three electrode units 310 are located in the second to fourth columns; the third row has three electrode units 310, namely electrode units M6, M8, and M7, and these three electrode units 310 are located in the second to fourth columns; the fourth row has four electrode units 310, namely electrode units M12, M9, M11, and M10, and these four electrode units 310 are located in the first to fourth columns. The four ground traces 318B are respectively connected to the ground terminals 3151 of the multiple temperature sensors 315 in the corresponding rows, and the signal terminals 3152 of the multiple temperature sensors 315 connected to each ground trace 318B are respectively connected to different signal traces 318C, that is, the signal terminals 3152 of each temperature sensor 315 in each row are respectively connected to different detection channels in the adapter 20 through different signal traces 318C; each of the four signal traces 318C is connected to the signal terminals 3151 of at least one temperature sensor 315. The signal terminals 3152 of the temperature sensors 315 are connected to different grounding traces 318B through the grounding terminals 3151 of the temperature sensors 315 connected to the same signal trace 318C. The signal terminals 3152 of the temperature sensors 315 in the same column are connected to the same detection channel in the adapter 20 through the same signal trace 318B, and the signal terminals 3152 of the temperature sensors 315 in different columns are connected to different detection channels of the adapter 20 through different signal traces 318C. When measuring temperature, the four signal traces 318C are all turned on, and then the grounding trace 318B is turned on in turn, so that the temperature detection signals of the temperature sensors 315 in each row can be obtained in turn in time sharing.

[0050] The adapter 20 includes: a controller 21, multiple groups of analog-to-digital conversion modules 22 connected to the controller 21, multiple groups of pressure resistors 24 and multiple groups of grounding switches 25 corresponding to the multiple groups of analog-to-digital conversion modules 22, a communication unit 23, and a power module 26 connected to the communication unit 23, the controller 21, and the multiple groups of analog-to-digital conversion modules 22. The power module 26 provides a DC power supply VCC for each electronic component of the adapter 20. The adapter 20 also includes multiple circuit lines (unnumbered). The multiple circuit lines (unnumbered) are electrically connected to multiple ground traces 318B, multiple signal traces 318C, and AC signal traces 318A in the substrate 313 of the electrode sheet 30 through the wires of the corresponding electrode sheet 30. The multiple circuit lines (unnumbered) include multiple AC lines 27 that transmit alternating current signals to the corresponding electrode sheets 30 and are electrically connected to the AC signal traces 318A in the substrate 313 of the corresponding electrode sheets 30, multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiple signal traces 318C in the substrate 313 of the corresponding electrode sheets 30 and are used to supply power to the temperature sensors 315 of the electrode sheets 30 or to transmit the temperature detection signals of the electrode sheets 30, and multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiple ground traces 318B in the substrate 313 of the corresponding electrode sheets 30. The number of circuit lines P of the adapter 20 electrically connected to an electrode sheet 30 is equal to the sum of the number of row groups M and the number of column groups N of the electrode units 310 of the electrode sheet 30 in the circuit connection plus 1; the number of circuits H of the adapter 20 electrically connected to X electrode sheets 30 is equal to X times the number of circuit lines electrically connected to a single electrode sheet 30, that is, H=XP=X*(M+N+1). The number of groups of grounding switches 25 is related to the number of electrode sheets 30. The number of groups of grounding switches 25 is not less than the number of electrode sheets 30. Preferably, the number of groups of grounding switches 25 is the same as the number of electrode sheets 30. The following is a detailed description taking the electrical connection between one electrode sheet 30 and the adapter 20 as an example.

[0051] Each group of grounding switches 25 is provided with a plurality of grounding switches 25, which are respectively connected to the adapter 20 and are respectively electrically connected to the circuit lines (not numbered) corresponding to the multi-path grounding traces 318B of the corresponding electrode sheet 30, and are configured to control the conduction or disconnection of the multi-path grounding traces 318B. The circuit lines (not numbered) that are respectively electrically connected to the multi-path grounding traces 318B of the electrode sheet 30 are grounded at one end close to the grounding switch 25. The number of grounding switches 25 in each group of grounding switches 25 is related to the number of grounding traces 318B of the substrate 313 of the corresponding electrode sheet 30, and the two are equal in this embodiment. Fig. 9As shown, in this embodiment, each group of grounding switches 25 is provided with a plurality of grounding switches 25, and in this embodiment, there are four grounding switches 25, namely, a first grounding switch 25-1, a second grounding switch 25-2, a third grounding switch 25-3 and a fourth grounding switch 25-4. The plurality of grounding switches 25 in each group respectively control the closing or opening of the corresponding grounding trace 318B of a corresponding electrode sheet 30.

[0052] Specifically, in terms of the circuit connection of the electrode unit 310, the ground ends 3151 of the temperature sensors 315 of the three electrode units M1, M2, and M13 located in the first row are short-circuited in parallel to the first ground trace 318B-1, the ground ends 3151 of the temperature sensors 315 of the three electrode units M3, M5, and M4 located in the second row are short-circuited in parallel to the second ground trace 318B-2, the ground ends 3151 of the temperature sensors 315 of the three electrode units M6, M8, and M7 located in the third row are short-circuited in parallel to the third ground trace 318B-3, and the ground ends 3151 of the temperature sensors 315 of the four electrode units M12, M9, M11, and M10 located in the fourth row are short-circuited in parallel to the fourth ground trace 318B-4. The first grounding switch 25-1 is used to control the closing or disconnection of the first grounding trace 318B-1 of the corresponding electrode sheet 30, thereby controlling the power on and off of each temperature sensor 315 of each electrode unit 310 in the first row of the electrode sheet 30; the second grounding switch 25-2 is used to control the closing or disconnection of the second grounding trace 318B-2 of the electrode sheet 30, thereby controlling the power on and off of each temperature sensor 315 of each electrode unit 310 in the second row of the electrode sheet 30; the third grounding switch 25-3 is used to control the closing or disconnection of the third grounding trace 318B-3 of the electrode sheet 30, thereby controlling the power on and off of each temperature sensor 315 of each electrode unit 310 in the third row of the electrode sheet 30; the fourth grounding switch 25-4 is used to control the closing or disconnection of the fourth grounding trace 318B-4 of the electrode sheet 30, thereby controlling the power on and off of each temperature sensor 315 of each electrode unit 310 in the fourth row of the electrode sheet 30. The grounding switch 25 may be a mechanical switch, such as a relay. The grounding switch 25 may also be an electronic switch. Each grounding switch 25 may be opened and closed by the controller 21 of the adapter 20 .

[0053] In this embodiment, the multiple groups of grounding switches 25 are all electronic switches. The controller 21 is connected to the multiple groups of grounding switches 25 for sequentially and cyclically controlling the opening and closing states of multiple grounding switches 25 in each group of grounding switches 25, and then sequentially and individually conducting each grounding trace 318B in the multiple grounding traces 318B of the corresponding electrode sheet 30, so as to sequentially and time-dividedly collect the temperature detection signals of the patient's body surface detected by all the temperature sensors 315 on the electrode sheet 30 during the period when the corresponding electrode sheet 30 stops applying the alternating current signal. The number of each group of grounding switches 25 is greater than or equal to the number of grounding traces 318B of the substrate 313 of the corresponding electrode sheet 30. In this embodiment, the number of each group of grounding switches 25 is the same as the number of grounding traces 318B of the corresponding electrode sheet 30.

[0054] In the present embodiment, each group of analog-to-digital conversion modules 22 is electrically connected one by one to each signal trace 318C of the substrate 313 in the corresponding electrode sheet 30 through the multi-channel circuit lines (unnumbered) in the adapter 20, and is configured to receive the temperature detection signal transmitted from the multi-channel signal trace 318C of the corresponding electrode sheet 30, and convert the temperature detection signal from an analog signal to a digital signal. Each group of analog-to-digital conversion modules 22 includes a plurality of detection channels A, B, C, and D, and each detection channel A, B, C, and D is used to connect to a corresponding signal trace 318C in the multi-channel signal trace 318C. The number of detection channels in each group of analog-to-digital conversion modules 22 is related to the number of column groups of the electrode units 310 of the corresponding electrode sheet 30 in the circuit connection. Specifically, the number of detection channels in each group of analog-to-digital conversion modules 22 is not less than the number of column groups of the electrode units 310 of the corresponding electrode sheet 30 in the circuit connection. Fig. 9As shown, each group of analog-to-digital conversion modules 22 includes a total of 4 detection channels A, B, C, and D, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, and the fourth detection channel D. The signal end 3152 of the temperature sensor 315 of the single electrode unit M12 located in the first column is connected to the first signal trace 318C-1, the signal end 3152 of the temperature sensor 315 of the four electrode units M1, M3, M6, and M9 located in the second column is connected in parallel to the second signal trace 318C-2, the signal end 3152 of the temperature sensor 315 of the four electrode units M2, M5, M8, and M11 located in the third column is connected in parallel to the third signal trace 318C-3, and the signal end 3152 of the temperature sensor 315 of the four electrode units M13, M4, M7, and M10 located in the fourth column is connected in parallel to the fourth signal trace 318C-4. The first detection channel A is connected to the first signal trace 318C-1, the second detection channel B is connected to the second signal trace 318C-2, the third detection channel C is connected to the third signal trace 318C-3, and the fourth detection channel D is connected to the fourth signal trace 318C-4. Each detection channel A, B, C, D is used to receive the temperature detection signal collected by the temperature sensor 315 of the electrode unit 310 connected to the corresponding signal trace 318C. In addition, each detection channel A, B, C, D is connected to a power module 26 for providing a detection voltage to the detection channel A, B, C, D via a corresponding voltage divider resistor 24 in the adapter 20, and the power module 26 provides a DC signal.

[0055] In this embodiment, the communication unit 23 is configured to obtain the digital signals output by the multiple analog-to-digital conversion modules 22 and send the digital signals to the electric field generator 10. The electric field generator 10 is also configured to control and adjust the voltage, current or power of the AC signal provided to the multiple electrode units 310 of the electrode sheet 30 according to the received digital signals. Exemplarily, when any of the multiple digital signals received exceeds the preset threshold value stored in the controller 21, it means that the temperature of the human body surface to which the corresponding dielectric element 314 is attached detected by at least one temperature sensor 315 in the electrode sheet 30 exceeds the preset threshold temperature (for example, 41°C, 42°C, etc.), and at this time, the voltage, current or power of the AC signal output by the electric field generator 10 can be appropriately reduced to avoid the electrode unit 310 of the electrode sheet 30 from being too high in temperature when the AC signal is applied, causing low-temperature burns to the patient's skin. The above-mentioned preset threshold temperature and preset threshold value can be determined according to the human safety threshold value. The communication unit 23 is controlled by the controller 21 and transmits the digital signals converted by the multiple analog-to-digital conversion modules 22 in series. In this embodiment, the preset temperature threshold may be a value within the range of 36°C-45°C.

[0056] When it is necessary to apply an AC signal to each electrode unit 310 of the corresponding electrode sheet 30, the corresponding four grounding switches 25-1 to 25-4 are all disconnected, and the electric field generator 10 outputs the AC signal to the corresponding AC line 27 in the adapter 20, and applies it to the dielectric element 314 of each electrode unit 310 through the AC signal trace 318A connected to the AC line 27.

[0057] When it is necessary to collect the temperature detection signal of each temperature sensor 315 in the corresponding electrode sheet 30, the electrical connection between the AC signal trace 318A of the electrode sheet 30 and the AC line 27 of the adapter 20 is disconnected, and the four signal traces 318C are always turned on. The first grounding switch 25-1 is closed first, and the other grounding switches 25-2 to 25-4 are all disconnected. The three detection channels B, C and D of the analog-to-digital conversion module 22 can obtain the temperature detection signal at the same time. Fig. 9 Then close the second grounding switch 25-2, and the other grounding switches 25-1, 25-3 and 25-4 are all disconnected, and the three detection channels B, C and D of the analog-to-digital conversion module 22 can obtain the temperature detection signals of the three electrode units M1, M2 and M13 in the first row shown in FIG. Fig. 9 The temperature detection signals of the three electrode units M3, M4, and M5 in the second row shown in FIG. 2 are obtained by closing the third grounding switch 25-3, and the other grounding switches 25-1, 25-2, and 25-4 are all disconnected. The three detection channels B, C, and D of the analog-to-digital conversion module 22 can be obtained simultaneously. Fig. 9 Finally, the fourth grounding switch 25-4 is closed, and the other grounding switches 25-1, 25-2 and 25-3 are all disconnected, and the four detection channels A, B, C and D of the analog-to-digital conversion module 22 can obtain the temperature detection signals of the three electrode units M6, M8 and M7 in the third row shown in FIG. Fig. 9 The temperature detection signals of the four electrode units M12, M9, M11, and M10 in the fourth row are shown in FIG. In this way, the temperature detection signals of all the temperature sensors 315 can be collected.

[0058] The communication unit 23 is controlled by the controller 21 and transmits the digital signal converted by the analog-to-digital conversion module 22 in series, and sends the digital signal to the electric field generator 10. When any of the multiple digital signals received by the electric field generator 10 exceeds a preset threshold, the voltage, current or power of the AC signal output by the electric field generator 10 can be appropriately reduced to prevent a certain electrode unit 310 from being overheated and causing low-temperature burns to the patient's skin.

[0059] The above is only a preferred implementation mode of the present application and is not intended to limit the present application. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present application should be included in the scope of protection of the present application.

Claims

1. A tumor electric field treatment system, comprising an electric field generator and a plurality of pairs of electrodes electrically connected to the electric field generator, wherein the electrode sheets comprise an electrode array, characterized in that: The electrode array includes a trunk and a plurality of branches extending radially from the trunk, wherein the trunk is provided with a plurality of electrode units and a connection portion connecting two adjacent electrode units; the branch is also provided with an electrode unit and a connection portion connecting the electrode unit to the trunk, and each electrode unit located on the branch is only connected to the trunk through a corresponding connection portion; the electrode array also has an AC signal trace for transmitting alternating current signals to each electrode unit, a plurality of ground traces for short-circuiting the ground ends of the corresponding electrode units to ground, and a plurality of signal traces for connecting the signal ends of the corresponding electrode units in parallel and cooperating with the ground traces to transmit the temperature detection signals of the corresponding electrode units in time-sharing.

2. The tumor electric field treatment system according to claim 1, characterized in that: The electrode units include a plurality of central electrode units disposed on the trunk and a plurality of peripheral electrode units disposed on the branches, and each of the peripheral electrode units is connected only to the most adjacent central electrode unit through the corresponding connecting portion.

3. The tumor electric field treatment system according to claim 1, characterized in that: The electrode units are divided into multiple rows and columns in terms of circuit connection. The ground ends of the electrode units in each row are connected to the same ground trace, and the signal ends of the electrode units in each column are connected to the same signal trace. The AC signal trace connects each electrode unit.

4. The tumor electric field treatment system according to claim 3, characterized in that: The tumor electric field therapy system also includes an AC line, a plurality of grounding switches and a plurality of detection channels, the AC line is connected to the AC signal trace, the grounding trace is connected to the grounding switch in a one-to-one correspondence, and the signal trace is connected to the detection channel in a one-to-one correspondence; the detection channels are all turned on when collecting the temperature detection signal of the electrode unit, and the grounding switches are closed individually and in sequence when collecting the temperature detection signal of the electrode unit.

5. The tumor electric field treatment system according to claim 3, characterized in that: Each of the electrode units is provided with a temperature sensor, and the temperature sensor is provided with a ground terminal and a signal terminal. The ground terminal of the temperature sensor is the ground terminal of the corresponding electrode unit, and the signal terminal of the temperature sensor is the signal terminal of the corresponding electrode unit.

6. The tumor electric field treatment system according to claim 1, characterized in that: There are thirteen electrode units and four ground traces, wherein each of the three ground traces is respectively connected to the ground ends of the three electrode units, and the other ground trace is connected to the ground ends of the remaining four electrode units; there are four signal traces, wherein each of the three signal traces is respectively connected to the signal ends of the four electrode units, and the other signal trace is only connected to the signal end of the remaining one electrode unit.

7. The tumor electric field treatment system according to claim 6, characterized in that: The thirteen electrode units are spatially arranged into five rows and five columns, the first row and the fifth row each have two electrode units and are respectively located on the second column and the fourth column, the middle three rows each have three electrode units and are respectively located on the first column, the third column and the fifth column; in terms of circuit connection, the ground ends of the two electrode units in the first row and any electrode unit in the fifth row are each connected to one ground trace; the ground ends of the three electrode units in the second row are each connected to one ground trace; the ground ends of the three electrode units in the third row are each connected to one ground trace; the ground ends of the three electrode units in the fourth row and the remaining electrode unit in the fifth row are each connected to one ground trace.

8. The tumor electric field treatment system according to claim 7, characterized in that: In terms of circuit connection, the signal end of any electrode unit located in the fifth row is connected to one signal trace; the signal ends of the three electrode units located in the third column and the remaining electrode unit located in the fifth row are respectively connected to one signal trace; the signal ends of the three electrode units located in the first column and any electrode unit located in the first row are respectively connected to one signal trace; the signal ends of the three electrode units located in the fifth column and the remaining electrode unit located in the first row are respectively connected to one signal trace.

9. The tumor electric field treatment system according to claim 1, characterized in that: The electrode array is provided with a flexible substrate, and most of the ground traces and the signal traces are arranged on the back of the substrate; each electrode unit is provided with a conductive plate located on the front of the substrate, and the AC signal trace is arranged on the front of the substrate and connected to each conductive plate.

10. The tumor electric field treatment system according to claim 9, characterized in that: Part of the ground traces and / or part of the signal traces pass through the substrate to the front side of the substrate for jumpering and then pass back to the back side of the substrate for further arrangement.

11. The tumor electric field treatment system according to claim 9, characterized in that: The electrode array is provided with a wiring part, and a plurality of gold fingers are respectively provided on the front and back sides of the wiring part. The end of each ground trace passes through the wiring part and is connected to the corresponding gold finger located on the front side of the wiring part, and the end of each signal trace is connected to the corresponding gold finger located on the back side of the wiring part.

12. The tumor electric field treatment system according to claim 9, characterized in that: The electrode unit is provided with a dielectric element electrically connected to the conductive disk.

13. The tumor electric field treatment system according to claim 5, characterized in that: The electrode unit is provided with a diode connected in series between the ground terminal of the temperature sensor and the ground trace.

Images