Kaolin composite piezoelectric antibacterial fabric and mask product thereof

Abstract

The application relates to the technical field of antibacterial fabrics, in particular to a kaolin composite piezoelectric antibacterial fabric and a mask product thereof. The kaolin composite piezoelectric antibacterial fabric provided by the application is a fabric as a carrier loaded with a kaolin composite antibacterial material; the preparation method of the kaolin composite antibacterial material is as follows: high-klaolin, anhydrous Zn(NO3)2, anhydrous Na2CO3 and anhydrous NaCl are high-speed ball milled at room temperature for 0.5-1h to obtain a solid ball milling product which is calcined to obtain the kaolin composite antibacterial material, wherein the loading amount of ZnO is not less than 25%, and the ZnO is embedded into the kaolin. The prepared kaolin composite antibacterial material has a surface embedding configuration of nano-ZnO, the piezoelectric property of the kaolin composite antibacterial material is enhanced, efficient interface charge transfer is ensured, and thus efficient antibacterial property of the fabric under the action of external force is realized.

Description

Technical Field

[0001] This invention relates to the field of antibacterial fabric technology, and in particular to a kaolin composite piezoelectric antibacterial fabric and its mask products. Background Technology

[0002] Today, bacterial infections and multidrug resistance pose significant challenges to public health. The increasing prevalence of antibiotic resistance has spurred the development of new strategies and materials to address this crisis. Therefore, the research and development of antibacterial materials and products is of great importance to social production and people's lives. In recent years, antibacterial nanomaterials have become a research hotspot in the field of antibacterial medicine due to their ability to avoid the problem of antibiotic resistance. Membrane respiration, a necessary activity of bacterial cells, provides energy for metabolism. Electrons play a crucial role in membrane respiration; therefore, electron transfer is a common behavior in bacteria. Since the respiratory chain is located on the cell membrane, single-celled bacteria often exchange electrons with the medium upon contact. If the normal electron transfer process is disrupted, membrane respiration is inhibited, leading to bacterial death. Furthermore, this process is independent of the chemical composition of the materials used, effectively avoiding the generation of antibiotic resistance and toxic byproducts. In addition, it has been reported that 80% of bacteria are transmitted through surface contact; flexible antibacterial fabrics can interfere with electron transfer within bacteria and inactivate them, which is of great significance in preventing bacterial contamination and spread.

[0003] Medical protective masks play a vital role in preventing the spread of respiratory diseases in daily life by effectively blocking respiratory droplets, including influenza and the common cold. However, ordinary medical protective masks have limited functionality and lack antibacterial properties; they can only protect against infection but cannot effectively kill bacteria. Therefore, how to imbue ordinary medical masks with antibacterial properties while maintaining low production costs and simple manufacturing processes is a pressing issue in the current research and development of antibacterial medical masks. Summary of the Invention

[0004] The purpose of this invention is to address the aforementioned shortcomings of the prior art by providing a kaolin composite piezoelectric antibacterial fabric and its mask product.

[0005] The present invention discloses a piezoelectric antibacterial fabric with kaolin as a carrier, wherein the fabric is used as a carrier to load kaolin composite antibacterial material; the preparation method of the kaolin composite antibacterial material is as follows: kaolin, anhydrous Zn(NO3)2, anhydrous Na2CO3, and anhydrous NaCl are ball-milled at high speed at room temperature for 0.5-1h to obtain a solid ball-milled product, which is then calcined. The loading of ZnO is not less than 25%, and the ZnO is embedded in the kaolin.

[0006] Furthermore, the calcination temperature is 400℃.

[0007] Furthermore, the kaolin composite piezoelectric antibacterial fabric generates a strong piezoelectric effect under external force.

[0008] Furthermore, the method of loading kaolin composite antibacterial material onto fabric is as follows: prepare a suspension by mixing kaolin composite antibacterial material, PVP and deionized water in a certain proportion, then immerse the fabric in the suspension, and then roll, dry and cut it.

[0009] Furthermore, the concentration range of the kaolin antibacterial material in the suspension is 0.01-0.5 g / mL.

[0010] Furthermore, the concentration of PVP in the suspension ranged from 0.005 to 0.01 g / mL.

[0011] Furthermore, the fabric is immersed in the suspension for 5-10 minutes.

[0012] A mask product includes an outer mask layer and an inner mask layer, wherein a meltblown fabric antibacterial layer is provided between the outer mask layer and the inner mask layer, and the meltblown fabric antibacterial layer is a kaolin composite piezoelectric antibacterial fabric as described above, and the fabric is meltblown fabric.

[0013] Furthermore, the force generated by breathing during the wearing of the mask causes a strong piezoelectric effect in the meltblown fabric antibacterial layer.

[0014] The kaolin composite antibacterial material prepared by this invention has nano-ZnO embedded in its surface, which enhances the piezoelectric properties of the kaolin composite antibacterial material and ensures efficient interfacial charge transfer, thereby achieving efficient antibacterial properties of the fabric when subjected to external forces.

[0015] The mask product of this invention has significant antibacterial properties against Staphylococcus aureus and Escherichia coli, solving the problem that ordinary medical masks do not have antibacterial properties. The antibacterial rate is >99% as tested.

[0016] The mask product of the present invention utilizes the force generated by breathing during wear to cause the antibacterial layer to have a piezoelectric effect, generating interfacial electrons. The transfer of electrons between bacteria and kaolin antibacterial material inhibits bacterial growth and leads to bacterial death.

[0017] The medical protective antibacterial mask provided by this invention has strong antibacterial properties, low cost, and simple manufacturing process, which is conducive to industrial production. Attached Figure Description

[0018] Figure 1 This is a scanning electron microscope image of kaolin.

[0019] Figure 2 High-resolution transmission electron microscope image of kaolin composite antibacterial material;

[0020] Figure 3 X-ray diffraction pattern of kaolin composite antibacterial material;

[0021] Figure 4 The piezoelectric coefficient of the ZnO and kaolin composite antibacterial material;

[0022] Figure 5 The image shows the antibacterial effect of the kaolin composite antibacterial material prepared for different ball milling times in Example 4 on Escherichia coli and Staphylococcus aureus.

[0023] Figure 6 The antibacterial effect of ZnO-kaolin composite antibacterial materials with different embedding amounts on Escherichia coli and Staphylococcus aureus by vibration;

[0024] Figure 7 Scanning electron microscope image and corresponding elemental mapping diagram of the antibacterial layer of meltblown fabric prepared in Example 7;

[0025] Figure 8 The image shows the antibacterial effect of applying external force to the kaolin composite piezoelectric antibacterial fabric prepared in Example 8 against Escherichia coli and Staphylococcus aureus.

[0026] Figure 9 The image shows the antibacterial effect of the kaolin composite piezoelectric antibacterial fabric prepared in Example 7 on Escherichia coli and Staphylococcus aureus. Detailed Implementation

[0027] The following are specific embodiments of the present invention, which are described in conjunction with the accompanying drawings. However, the present invention is not limited to these embodiments.

[0028] Example 1

[0029] This embodiment provides a method for preparing a kaolin composite antibacterial material. 0.675g of uniform kaolin powder, 1.5g of anhydrous Zn(NO3)2, 1.5g of anhydrous Na2CO3, and 3.85g of anhydrous NaCl are weighed and added to a ball mill jar at room temperature for high-speed ball milling for 0.5h to obtain a solid ball-milled product. The product is then calcined at 400℃. After calcination, the calcined product is taken out, washed, and dried to obtain the kaolin composite antibacterial material.

[0030] Example 2

[0031] This embodiment provides a method for preparing a kaolin composite antibacterial material. 1.35g of uniform kaolin powder, 1.5g of anhydrous Zn(NO3)2, 1.5g of anhydrous Na2CO3, and 3.85g of anhydrous NaCl are weighed and added to a ball mill jar at room temperature for high-speed ball milling for 0.5h to obtain a solid ball-milled product. The product is then calcined at 400℃. After calcination, the calcined product is taken out, washed, and dried to obtain the kaolin composite antibacterial material.

[0032] Example 3

[0033] This embodiment provides a method for preparing a kaolin composite antibacterial material. 2.7g of uniform kaolin powder, 1.5g of anhydrous Zn(NO3)2, 1.5g of anhydrous Na2CO3, and 3.85g of anhydrous NaCl are weighed and added to a ball mill jar at room temperature for high-speed ball milling for 0.5h to obtain a solid ball-milled product. The product is then calcined at 400℃. After calcination, the calcined product is taken out, washed, and dried to obtain the kaolin composite antibacterial material.

[0034] Example 4

[0035] This embodiment provides a method for preparing kaolin composite antibacterial materials with different ball milling times. 2.7g of uniform kaolin powder, 1.5g of anhydrous Zn(NO3)2, 1.5g of anhydrous Na2CO3, and 3.85g of anhydrous NaCl are weighed and added to a ball mill jar at room temperature for high-speed ball milling for different times (0.5h, 1.0h, 2.0h, 4.0h, 6.0h, and 8.0h) to obtain solid ball milling products prepared at different ball milling times. These products are then calcined at 400℃. After calcination, the calcined products are taken out, washed, and dried to obtain the kaolin composite antibacterial material.

[0036] Example 5

[0037] This embodiment provides a method for preparing a kaolin composite antibacterial material. 5.4g of uniform kaolin powder, 1.5g of anhydrous Zn(NO3)2, 1.5g of anhydrous Na2CO3, and 3.85g of anhydrous NaCl are weighed and added to a ball mill jar at room temperature for high-speed ball milling for 0.5h to obtain a solid ball-milled product. The product is then calcined at 400℃. After calcination, the calcined product is taken out, washed, and dried to obtain the kaolin composite antibacterial material.

[0038] Example 6

[0039] This embodiment provides a method for preparing a kaolin composite antibacterial material. 8.1g of uniform kaolin powder, 1.5g of anhydrous Zn(NO3)2, 1.5g of anhydrous Na2CO3, and 3.85g of anhydrous NaCl are weighed and added to a ball mill jar at room temperature for high-speed ball milling for 0.5h to obtain a solid ball-milled product. The product is then calcined at 400℃. After calcination, the calcined product is taken out, washed, and dried to obtain the kaolin composite antibacterial material.

[0040] Example 7

[0041] A method for preparing a kaolin composite piezoelectric antibacterial fabric

[0042] Weigh 1g of the kaolin composite antibacterial material prepared in Example 1, 0.5g of PVP and 100mL of deionized water to make a uniform suspension. Then, the meltblown fabric is immersed in the uniform suspension for 10min. After rolling and drying, the meltblown fabric antibacterial layer, namely the kaolin composite piezoelectric antibacterial fabric, is obtained.

[0043] Example 8

[0044] A method for preparing a kaolin composite piezoelectric antibacterial fabric

[0045] Weigh 2.0g of the kaolin composite antibacterial material prepared in Example 1, 1.0g of PVP and 100mL of deionized water to make a homogeneous suspension. Then, immerse the meltblown fabric in the homogeneous suspension for 10min. After rolling and drying, the meltblown fabric antibacterial layer, namely the kaolin composite piezoelectric antibacterial fabric, is obtained.

[0046] External force was applied by oscillation: antibacterial experiments against Escherichia coli and Staphylococcus aureus were conducted using the kaolin composite antibacterial materials prepared in Examples 1-6 and the kaolin composite piezoelectric antibacterial fabric prepared in Example 7.

[0047] (1) Bacterial activation: Take out the preserved E. coli and S. aureus from the 4℃ refrigerator and put them into the microbial safety cabinet. Use an inoculation loop to take out one colony and add it to 5mL of liquid culture medium. Incubate in a constant temperature shaker for 12h at 180r / min and 37℃.

[0048] (2) Bacterial suspension dilution: Take out the two bacterial suspensions that have been revived for 12 hours and label them E0 and S0. Then take the required 1.5 mL sterile centrifuge tubes and label them accordingly. Add 900 μL of LB liquid medium to the first centrifuge tube. Take 100 μL of the bacterial suspension that has been activated for 12 hours and add it to the 1.5 mL centrifuge tube. Mix well with a pipette and then perform serial dilution. Dilute the bacterial suspension to 10. 5 -10 6 CFU mL -1 That's all.

[0049] (3) Addition of antibacterial material: Prepare 50mL sterile centrifuge tubes as needed and label them. The control group centrifuge tubes do not contain antibacterial material, but only 10mL of LB culture medium. The experimental group centrifuge tubes contain 50mg of antibacterial material. Then take 100μL of the diluted bacterial solution in (2) and add it to the control group and experimental group test tubes respectively. Place them in a constant temperature shaker at 37℃ and rotate at 180r / min for 4h.

[0050] Plate coating: After sterilizing the prepared petri dishes, place them in a biosafety cabinet and label them. Take 50 μL of bacterial culture from the control group and experimental group that have been incubated for 4 hours and add it to each petri dish. Then add 4 sterile glass beads to each petri dish and roll in each direction for 2 minutes. Coat each sample with 3 petri dishes as parallel groups. Finally, place the coated petri dishes in a constant temperature incubator and incubate for 15 hours at 37℃.

[0051] Plate counting and photography: calculate antibacterial rate and compare antibacterial performance.

[0052] All the above antibacterial experiments were conducted in a biosafety cabinet in the microbiology laboratory.

[0053] Antibacterial experiments were conducted on Escherichia coli and Staphylococcus aureus using a piezoelectric antibacterial fabric made of kaolin composite by applying external force through slight hand pinching.

[0054] (1) Activation of bacterial culture: Take out the preserved E. coli and S. aureus from the 4℃ refrigerator and put them into the microbial safety cabinet. Use an inoculation loop to take one colony and add it to 5mL of liquid culture medium. Incubate on a constant temperature shaker for 12h at 180r / min and 37℃.

[0055] (2) Bacterial suspension dilution: Take out the bacterial suspension that has been revived for 12 hours and label it as E0 and S0. Then take the required 1.5 mL sterile centrifuge tubes and label them accordingly. Add 900 μL of LB liquid medium to the first centrifuge tube. Take 100 μL of the bacterial suspension that has been activated for 12 hours and add it to the 1.5 mL centrifuge tube. Mix well with a pipette and then perform serial dilution. Dilute the bacterial suspension to 10⁻⁶. 5 -10 6 CFU mL -1 That's all.

[0056] (3) Interaction between the antibacterial layer of meltblown fabric and bacterial solution: The antibacterial layer of meltblown fabric is pre-cut into 2cm x 2cm squares, and 100μL of bacterial (Staphylococcus aureus and Escherichia coli) suspension diluted in (2) is dropped onto its surface. 5 ~10 6 (CFU / mL). Then, each sample was subjected to 300 slight bends for 3 minutes.

[0057] Plate coating: After sterilizing the prepared petri dishes, place them in a biosafety cabinet and label them. Add 50 μL of the treated bacterial suspension from both the control and experimental groups to each petri dish. Then add 4 sterile glass beads to each petri dish and roll in each direction for 2 minutes. Coat each sample onto 3 petri dishes as parallel groups. Finally, place the coated petri dishes in a constant temperature incubator and incubate for 15 hours at 37℃.

[0058] Plate counting and photography: calculate antibacterial rate and compare antibacterial performance.

[0059] All the above antibacterial experiments were conducted in a biosafety cabinet in the microbiology laboratory.

[0060] Figure 1 This is a scanning electron microscope image of kaolin. From the image, we can clearly see that the kaolin has a morphology of flakes and tubules, with uneven size, irregular edges of the flakes, and aggregates that are stacked or worm-like.

[0061] Figure 2 This is a high-resolution transmission electron microscope image and corresponding elemental mapping diagram of the kaolin composite antibacterial material. The image shows that ZnO is embedded within the kaolin.

[0062] Figure 3 The image shows the X-ray diffraction pattern of the kaolin composite antibacterial material prepared in Example 1. As can be seen from the image, the main phases in this composite antibacterial material are kaolinite, halloysite, and zinc oxide, proving the successful preparation of the kaolin composite antibacterial material.

[0063] Figure 4 The figure shows the piezoelectric coefficients of the ZnO and kaolin composite antibacterial materials prepared in Example 3. As can be seen from the figure, the piezoelectric coefficient of the kaolin composite antibacterial material is higher than that of pure ZnO, indicating that the kaolin composite antibacterial material has stronger piezoelectric properties.

[0064] Figure 5 The graph shows the antibacterial effects of the kaolin composite antibacterial material prepared for different ball milling times in Example 4 against Escherichia coli and Staphylococcus aureus. As can be seen from the graph, the antibacterial effects against Escherichia coli and Staphylococcus aureus are very significant when the ball milling time is 0.5 h and 1.0 h.

[0065] Figure 6 The graph shows the antibacterial effect of ZnO-kaolin composite antibacterial materials with different embedding amounts on Escherichia coli and Staphylococcus aureus. As can be seen from the graph, when the kaolin content is 2.7g and the ZnO loading is 25%, the antibacterial rate against Escherichia coli and Staphylococcus aureus is >99%.

[0066] Figure 7The images show scanning electron microscope (SEM) images and elemental mapping diagrams of the antibacterial layer of the meltblown fabric prepared in Example 7. It can be seen that the kaolin composite antibacterial material is uniformly distributed on the surface of the meltblown fabric fibers.

[0067] Figure 8 The graph shows the antibacterial effect of applying external force to the meltblown fabric antibacterial layer prepared in Example 8 against Escherichia coli and Staphylococcus aureus. As can be seen from the graph, when no external force is applied, there is almost no antibacterial effect compared to the blank control, while the applied external force exhibits strong antibacterial properties against Escherichia coli and Staphylococcus aureus.

[0068] Figure 9 The image shows the antibacterial effect of the meltblown fabric antibacterial layer prepared in Example 7 against Escherichia coli and Staphylococcus aureus through vibration. Compared with the blank control, the antibacterial rate against Escherichia coli and Staphylococcus aureus reached 100% after vibration.

[0069] For any points not covered above, existing technologies shall apply.

[0070] Although specific embodiments of the present invention have been described in detail by way of examples, those skilled in the art should understand that the above examples are for illustrative purposes only and are not intended to limit the scope of the invention. Those skilled in the art can make various modifications or additions to the described specific embodiments or use similar methods to replace them, without departing from the direction of the invention or exceeding the scope defined by the appended claims. Those skilled in the art should understand that any modifications, equivalent substitutions, improvements, etc., made to the above embodiments based on the technical essence of the present invention should be included within the protection scope of the present invention.

Claims

1. A mask product, characterized in that: The mask includes an outer layer and an inner layer, with a meltblown antibacterial layer between the outer and inner layers. The meltblown antibacterial layer is a piezoelectric antibacterial fabric made of kaolin composite, and the fabric is meltblown fabric. The mask product generates a strong piezoelectric effect in the meltblown antibacterial layer during the breathing process of wearing it. A piezoelectric antibacterial fabric composited with kaolin is used as a carrier to load kaolin composite antibacterial material. The preparation method of the kaolin composite antibacterial material is as follows: kaolin, anhydrous Zn(NO3)2, anhydrous Na2CO3, and anhydrous NaCl are ball-milled at high speed at room temperature for 0.5-1 h to obtain a solid ball-milled product, which is then calcined. The loading of ZnO is not less than 25%, and the ZnO is embedded in the kaolin. The calcination temperature is 400℃; The kaolin composite piezoelectric antibacterial fabric generates a strong piezoelectric effect under external force.

2. The mask product as described in claim 1, characterized in that: The method of loading kaolin composite antibacterial material onto fabric is as follows: prepare a suspension by mixing kaolin composite antibacterial material, PVP and deionized water in a certain proportion, then immerse the fabric in the suspension, and then roll, dry and cut it.

3. A mask product as described in claim 2, characterized in that: The concentration range of the kaolin antibacterial material in the suspension is 0.01-0.5 g / mL.

4. A mask product as described in claim 2, characterized in that: The concentration of PVP in the suspension ranged from 0.005 to 0.01 g / mL.

5. A mask product as described in claim 2, characterized in that: The fabric should be immersed in the suspension for 5-10 minutes.

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