Deer placenta oral liquid and its processing technology

Abstract

Deer placenta oral liquid and its processing technology, relate to the field of nutrient solution, the deer placenta oral liquid contains the following raw materials in percentage by weight: deer placenta dry product: 1.0-2.0, American ginseng: 1.5-2.5, tangerine peel: 1.5-2.5, cyperus rotundus: 2.0-3.0, donkey-hide gelatin: 3.0-4.0, wolfberry: 2.0-3.0, atractylodes: 2.0-3.0, astragalus: 3.0-4.0, angelica: 3.0-4.5, corydalis: 2.0-3.0, wine peony root: 1.5-2.5, ganoderma lucidum spore powder: 2.0-3.0, prepared rehmannia root: 2.0-3.0 : 3.0-4.0, salvia miltiorrhiza: 1.5-2.5, 30°-60° liquor: 15-25, distilled water: 10-35. On the basis of the original formula, the present invention adds wolfberry, ganoderma lucidum spore powder, astragalus, American ginseng and other ingredients, all of which have significant immunomodulatory and anti-fatigue effects, further enriching the nutritional components and functionality of the product. Astragalus and ganoderma lucidum spore powder are especially added to the formula. These ingredients have significant effects of enhancing immune function, can effectively improve the body's resistance, and meet the needs of modern people for improving immunity.

Description

Technical Field

[0001] The present application relates to the field of nutrient solution, and in particular to deer placenta oral solution and its processing technology. Background Art

[0002] Deer placenta oral liquid, it relates to a nutrient solution, deer placenta oral liquid is a Chinese medicine preparation with deer placenta as the main ingredient, mainly used for nourishing and conditioning, regulating endocrine, replenishing blood and invigorating qi, etc. Its traditional formula is mostly derived from the classical theory and empirical prescription of traditional Chinese medicine, combined with modern technology. The existing deer placenta oral liquid is based on traditional Chinese medicine theory and has certain health care effects, especially in the health conditioning of women. However, its functionality and wide range of ingredients are difficult to meet the needs of modern consumers, especially in terms of enhancing immune function, anti-fatigue and expanding the scope of applicable population.

[0003] For example, Chinese invention patent CN1366998A discloses a deer placenta oral liquid and its processing technology, which contains the following raw materials in weight percentage: 0.5-1.5% dried deer placenta, 1-2% red ginseng, 2-3% dried orange peel, 2-3% cyperus rotundus, 2-3% donkey hide gelatin, 1-2% cinnamon bark, 2-3% atractylodes macrocephala, 1-2% taro, 4-6% angelica, 2-3% corydalis, 1.5-2.5% peony root, 2-3% processed potato, 4-5% cosmosus, 1.5-2.5% vinegar, 2-3% chuanxiong, 1.5-2.5% moutan bark, 1.5-2.5% salvia miltiorrhiza, 2-3% red astragalus, 2-3% wine-flavored poria, 3-4% cooked rehmannia, 2-3% urinary vine, 20-30% white wine at 30°-60°, and 7-39% distilled water. However, the existing deer placenta oral liquid has a single nutritional component, the dosage of each raw material is unreasonable, the health care effect is not obvious, and there are certain side effects. Summary of the invention

[0004] The purpose of the present application is to provide a deer placenta oral liquid and its processing technology, which has rich nutritional ingredients, improves health care effects, reduces side effects, and enhances human immune function.

[0005] The deer placenta oral liquid is characterized in that it contains the following raw materials in percentage by weight: dried deer placenta: 1.0-2.0, American ginseng: 1.5-2.5, dried tangerine peel: 1.5-2.5, cyperus rotundus: 2.0-3.0, donkey-hide gelatin: 3.0-4.0, wolfberry: 2.0-3.0, atractylodes: 2.0-3.0, astragalus: 3.0-4.0, angelica: 3.0-4.5, corydalis: 2.0-3.0, wine-peony root: 1.5-2.5, ganoderma lucidum spore powder: 2.0-3.0, rehmannia glutinosa: 3.0-4.0, salvia miltiorrhiza: 1.5-2.5, 30°-60° white wine: 15-25, and distilled water: 10-35. The newly added wolfberry, ganoderma lucidum spore powder and astragalus can enhance human immunity, and the use of American ginseng instead of red ginseng can improve the anti-fatigue and immune regulation effects.

[0006] The processing technology of the deer placenta oral liquid provided in the present application comprises the following steps: S1. Wash and steam the dried deer fetus, and grind it into fine powder after drying for later use. Slicing or grinding can increase the surface area of ​​the medicinal material, which is conducive to the extraction of effective ingredients and improves the extraction efficiency. Steaming and grinding can remove the fishy smell and release its nourishing ingredients, which is convenient for subsequent processing. S2. Other medicinal materials are also cleaned, sliced ​​or crushed after removing impurities for later use, and the Ganoderma lucidum spore powder is used directly without processing; S3. Except for Ganoderma lucidum spore powder and donkey-hide gelatin, dry medicinal materials are placed in an extraction tank according to proportion, distilled water is added, and the mixture is soaked for 2 hours. The soaking allows the medicinal materials to absorb water and soften the tissue structure, which facilitates the dissolution of the active ingredients in the subsequent extraction process. S4, after soaking, heating to 90°C, extracting at this temperature for 1-3 hours, filtering and extracting, repeating the extraction twice, combining the extracts for later use, and extracting at this temperature to fully release the main components in the medicinal materials, while avoiding high temperature damage to some heat-sensitive components; S5, concentrating the extract under low temperature and reduced pressure to a liquid medicine with a relative density of about 1.2, adding donkey-hide gelatin to the concentrated liquid, heating it over a warm fire until it is completely dissolved, stirring it evenly, reducing the volume of the liquid by reduced pressure evaporation, increasing the concentration of the active ingredient, making the liquid medicine more effective, and dissolving the donkey-hide gelatin by heating so that it is fully integrated with the liquid medicine to improve the nourishing and conditioning effects; S6, adding Ganoderma lucidum spore powder and Rehmannia glutinosa powder to the concentrated liquid medicine in proportion, stirring evenly, slowly adding white wine, stirring evenly, so that it is fully dissolved and mixed evenly; S7, heating the mixed solution to 80-90°C, sterilizing by heat preservation for 30 minutes, cooling to room temperature, filtering to remove impurities and suspended matter, and packaging the treated liquid into sterile oral liquid bottles and sealing; S8. Package the finished product and indicate the instructions for use, precautions and expiration date.

[0007] Preferably, in S7, the mixed solution is heated to 85°C.

[0008] Preferably, the heat preservation extraction time in S4 is 2 hours.

[0009] Preferably, the S4-S7 process should pay attention to hygiene and cleanliness to prevent harmful microorganisms from contaminating the finished product.

[0010] Compared with the prior art, the advantages of the present invention are: (1) The present invention adds wolfberry, ganoderma lucidum spore powder, astragalus, American ginseng and other ingredients to the original formula. These ingredients have significant immunomodulatory and anti-fatigue effects, further enriching the nutritional components and functionality of the product.

[0011] (2) The formula of the present invention specifically adds astragalus and ganoderma spore powder. These ingredients have a significant effect of enhancing immune function, can effectively improve the body's resistance, and meet the needs of modern people for improving immunity.

[0012] (3) The present invention not only has the effects of nourishing qi and blood and regulating endocrine, but also has the effects of anti-fatigue, anti-oxidation and anti-aging, which can meet the health needs of more people and solve the problem of single health care effect of existing products.

[0013] (4) The present invention retains the biological activity of the effective ingredients and improves the overall quality and efficacy of the product through low-temperature reduced pressure concentration and the addition of special ingredients such as Ganoderma lucidum spore powder.

[0014] (5) The present invention strictly controls the source of raw materials and optimizes the production process, thereby ensuring the high purity and high quality of the product, reducing the residual impurities, and making the product safer. DETAILED DESCRIPTION

[0015] The present application is further described in detail below in conjunction with examples, comparative examples and performance testing experiments. These examples should not be construed as limiting the scope of protection claimed in the present application. Example

[0016] Embodiment 1: Deer placenta oral liquid, it contains the following raw materials in weight percentage: deer placenta dry product: 1.0-2.0, American ginseng: 1.5-2.5, dried orange peel: 1.5-2.5, cyperus rotundus: 2.0-3.0, donkey-hide gelatin: 3.0-4.0, wolfberry: 2.0-3.0, atractylodes: 2.0-3.0, astragalus: 3.0-4.0, angelica: 3.0-4.5, corydalis: 2.0-3.0, wine peony root: 1.5-2.5, ganoderma lucidum spore powder: 2.0-3.0, prepared rehmannia: 3.0-4.0, salvia miltiorrhiza: 1.5-2.5, 30°-60° white wine: 15-25, distilled water: 10-35. Among them, dried deer placenta is 1.5, American ginseng is 2.0, wolfberry is 3.0, ganoderma lucidum spore powder is 2.5, astragalus is 4.0, donkey-hide gelatin is 3.5, and other ingredients are based on the main formula ratio.

[0017] The processing technology of deer placenta oral liquid includes the following steps: S1. Wash and steam the dried deer fetus, and grind it into fine powder after drying for later use. Slicing or grinding can increase the surface area of ​​the medicinal material, which is conducive to the extraction of effective ingredients and improves the extraction efficiency. Steaming and grinding can remove the fishy smell and release its nourishing ingredients, which is convenient for subsequent processing. S2. Other medicinal materials are also cleaned, sliced ​​or crushed after removing impurities for later use, and the Ganoderma lucidum spore powder is used directly without processing; S3. Except for Ganoderma lucidum spore powder and donkey-hide gelatin, dry medicinal materials are placed in an extraction tank according to proportion, distilled water is added, and the mixture is soaked for 2 hours. The soaking allows the medicinal materials to absorb water and soften the tissue structure, which facilitates the dissolution of the active ingredients in the subsequent extraction process. S4, after soaking, heating to 90°C, extracting at this temperature for 2 hours, filtering and extracting, repeating the extraction for 2 times, combining the extracts for later use, and extracting at this temperature to fully release the main components in the medicinal materials, while avoiding high temperature damage to some heat-sensitive components; S5, concentrating the extract under low temperature and reduced pressure to a liquid medicine with a relative density of about 1.2, adding donkey-hide gelatin to the concentrated liquid, heating it over a warm fire until it is completely dissolved, stirring it evenly, reducing the volume of the liquid by reduced pressure evaporation, increasing the concentration of the active ingredient, making the liquid medicine more effective, and dissolving the donkey-hide gelatin by heating so that it is fully integrated with the liquid medicine to improve the nourishing and conditioning effects; S6, adding Ganoderma lucidum spore powder and Rehmannia glutinosa powder to the concentrated liquid medicine in proportion, stirring evenly, slowly adding white wine, stirring evenly, so that it is fully dissolved and mixed evenly; S7, heating the mixed solution to 85°C, sterilizing at this temperature for 30 minutes, cooling to room temperature, filtering to remove impurities and suspended matter, and packaging the treated liquid into sterile oral liquid bottles and sealing them; S8. Package the finished product and indicate the instructions for use, precautions and expiration date.

[0018] Example 2: The difference from Example 1 is that the amount of dried deer placenta is 2.0, the amount of American ginseng is 2.5, the amount of wolfberry is 2.5, the amount of ganoderma lucidum spore powder is 3.0, the amount of astragalus is 3.5, and the amount of donkey-hide gelatin is 3.0.

[0019] Example 3: The difference from Example 1 is that the amount of dried deer placenta is 1.0, the amount of American ginseng is 2.0, the amount of wolfberry is 2.0, the amount of ganoderma lucidum spore powder is 2.5, the amount of astragalus is 4.0, and the amount of donkey-hide gelatin is 4.0.

[0020] Example 4: The difference from Example 1 is that the amount of dried deer placenta is 1.2, the amount of American ginseng is 1.8, the amount of wolfberry is 2.8, the amount of ganoderma lucidum spore powder is 2.0, the amount of astragalus is 3.8, and the amount of donkey-hide gelatin is 3.2.

[0021] Example 5: The difference from Example 1 is that the amount of dried deer placenta is 1.8, the amount of American ginseng is 2.2, the amount of wolfberry is 3.2, the amount of ganoderma lucidum spore powder is 2.6, the amount of astragalus is 4.2, and the amount of donkey-hide gelatin is 3.6.

[0022] Example 6: The difference from Example 1 is that the amount of dried deer placenta is 1.6, the amount of American ginseng is 2.0, the amount of wolfberry is 3.0, the amount of ganoderma lucidum spore powder is 2.4, the amount of astragalus is 3.6, and the amount of donkey-hide gelatin is 3.4.

[0023] Example 7: The difference from Example 1 is that the amount of dried deer placenta is 1.4, American ginseng is 1.9, wolfberry is 2.7, Ganoderma lucidum spore powder is 2.3, astragalus is 3.9, and donkey-hide gelatin is 3.3.

[0024] Comparative Example 1: The difference from Example 1 is that the original formula mentioned in the background technology is used to prepare the oral liquid according to its proportion.

[0025] Comparative Example 2: The difference from Example 1 is that, based on Example 1, the Ganoderma lucidum spore powder is removed, and other ingredients remain the same.

[0026] Comparative Example 3: The difference from Example 1 is that, based on Example 1, wolfberry is removed and other ingredients remain the same.

[0027] A comparative experiment is now conducted on Examples 1-7 and Comparative Examples 1-3 to test the superiority of the new formula in terms of health care effects, enhancement of human immune function, and differences in safety. The test steps are as follows: Step 1, according to the formula of Examples 1-7 and Comparative Examples 1-3, the processing technology of deer placenta oral liquid is used to prepare the respective finished products; Step 2: Select 100 healthy adult volunteers and divide them into 10 groups to ensure a balanced distribution of gender, age, and physical fitness, and exclude pregnant women, breastfeeding women, and those with a history of chronic diseases; Step 3: The finished products prepared in Examples 1-7 and Comparative Examples 1-3 were distributed to 10 groups respectively, and each person in each group took 10 ml per day for 8 consecutive weeks, during which time the test was conducted every 2 weeks.

[0028] The experimental results are shown in Table 1: Table 1 In terms of hemoglobin enhancement, Examples 1-7 are better than Comparative Examples 1-3. In particular, Examples 2 and 5 performed best, reaching +18g / L and +17g / L, respectively, showing that they are more effective in blood supplementation. In terms of fatigue score improvement, Examples 2 and 5 have significant improvement effects, indicating that they have significant advantages in relieving fatigue. In terms of IgG and IgA enhancement, Examples 2 and 5 both have outstanding performances, significantly higher than the comparative group, and Example 6 is slightly inferior, indicating that they have outstanding effects in enhancing immune function. The NK cell activity of Examples 1-7 is also significantly higher than that of Comparative Examples 1-3, and Comparative Example 3 has significantly decreased in terms of IgG enhancement and NK cell activity enhancement, indicating that wolfberry plays an important role in enhancing immune function. In terms of ALT levels, the liver function indicators of all groups are normal. The adverse reaction rates of Examples 1-7 were significantly lower than those of Comparative Examples 1-3, indicating that the improved formula has good safety and a low probability of side effects. In summary, Example 5 is second only to Example 2 in terms of comprehensive health care effects and immune function enhancement, but the effect is relatively stable. The experimental results of Comparative Example 3 verify the important role of wolfberry in immune function enhancement. Examples 2 and 5 can be further optimized as candidate main formulas, while other examples perform better but are slightly inferior, and can be used as auxiliary formulas for in-depth research. The safety test results show that all examples do not show obvious adverse reactions, and the probability of adverse reactions is lower than that of traditional formulas, supporting the safety and generalizability of the formulas.

[0029] Based on the above Examples 1-7 and Comparative Examples 1-3, and considering the actual situation, another experiment was conducted to focus on testing the differences in these formulas in terms of anti-fatigue effect and antioxidant effect. These two aspects are common application areas of health foods and are also the focus of consumers' attention. The experimental steps are as follows: Experiment 1: Anti-fatigue experiment Step 1: 60 healthy volunteers were selected and randomly divided into 10 groups, each group corresponding to an embodiment or a comparative example; Step 2: Each group of experimental subjects took 10 ml of the corresponding formula oral solution every day for 6 weeks, and the test was performed every 2 weeks; Step 3: The test subjects continued to run on a treadmill with a fixed power, and the fatigue reaching time was recorded. The test period was before the experiment and at the 2nd, 4th, and 6th week after the experiment; Step 4: Measure serum lactate concentration after exercise to evaluate the body's ability to clear fatigue metabolites; Step 5: Measure the glycogen content in the liver and muscles to assess energy reserve levels.

[0030] Experiment 2: Antioxidant Experiment Step 1: Select the same 60 people as those in Experiment 1, and conduct two experimental tests on each person to ensure that individual differences do not affect the results; Step 2: Each group of experimental subjects took 10 ml of the corresponding formula oral solution every day for 6 weeks, and the test was performed every 2 weeks; Step 3: Determine serum SOD levels to evaluate the activity of the antioxidant enzyme system in the body; Step 4: Determine serum MDA content, which reflects the degree of lipid peroxidation. The higher the free radical level, the higher the MDA content; Step 5: Determine the glutathione level to reflect the intracellular antioxidant capacity.

[0031] The experimental results are as follows: The results of the anti-fatigue test are shown in Table 2: Table 2 Antioxidant test results are shown in Table 3: Table 3 In terms of anti-fatigue effect, Example 2 and Example 5 performed best in fatigue reaching time, lactic acid reduction, and glycogen reserve improvement, reaching +20 minutes, -2.1mmol / L, and +3.0 mg / g, respectively. Comparative Example 1 and Comparative Example 3 performed the worst, verifying the significant anti-fatigue advantage of the new formula; in terms of antioxidant effect, Example 2 performed best in SOD improvement, MDA reduction, and GSH improvement, reaching +25U / mL, -3.2nmol / mL, and +1.2mg / mL, respectively, showing strong antioxidant ability, followed by Example 5 and Example 6, indicating that their comprehensive effects are good. The antioxidant indicators of Comparative Example 1 and Comparative Example 3 are significantly lower than those of the embodiment group, verifying the importance of key ingredients, such as Ganoderma lucidum spore powder and wolfberry, in antioxidant ability; in summary, Example 2 performed best, showing excellent performance in both anti-fatigue and antioxidant aspects. Example 5 follows closely, with stable effects, and can be used as a secondary formulation. The results of the comparative example further verify the irreplaceability of the key ingredients in the new formulation. This experiment provides strong data support for the practical application of the improved formulation, further proving its potential application value in health foods.

[0032] The basic principles, main features and advantages of the present invention are shown and described above; those skilled in the art should understand that the present invention is not limited to the above embodiments, and the above embodiments and descriptions are only preferred examples of the present invention and are not used to limit the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, and these changes and improvements all fall within the scope of the present invention to be protected; the scope of protection claimed by the present invention is determined by the attached claims and their effects.

Claims

1. Deer placenta oral liquid, characterized in that: The invention contains the following raw materials in percentage by weight: 1.0-2.0% dried deer placenta, 1.5-2.5% American ginseng, 1.5-2.5% dried orange peel, 2.0-3.0% cyperus rotundus, 3.0-4.0% donkey hide gelatin, 2.0-3.0% wolfberry, 2.0-3.0% atractylodes macrocephala, 3.0-4.0% astragalus, 3.0-4.0% angelica, 3.0-4.5% corydalis, 2.0-3.0% peony root, 1.5-2.5% wine, 2.0-3.0% ganoderma lucidum spore powder, 3.0-4.0% rehmannia root, 1.5-2.5% salvia miltiorrhiza, 15-25% 30-60% liquor, and 10-35% distilled water.

2. The processing technology of deer placenta oral liquid, which relates to the deer placenta oral liquid according to claim 1, characterized in that: The following steps are involved: S1, washing, steaming, drying and crushing the dried deer fetus into fine powder for later use; S2. Other medicinal materials are also cleaned, sliced ​​or crushed after removing impurities for later use, and the Ganoderma lucidum spore powder is used directly without processing; S3, except for Ganoderma lucidum spore powder and donkey-hide gelatin, put the dried medicinal materials in the extraction tank according to the proportion, add distilled water, and soak for 2 hours; S4, after soaking, heat to 90°C, extract at this temperature for 1-3 hours, filter and extract, repeat the extraction twice, and combine the extracts for later use; S5, concentrating the extract under low temperature and reduced pressure to a liquid with a relative density of about 1.2, adding donkey-hide gelatin to the concentrated liquid, heating over a warm fire until it is completely dissolved, and stirring evenly; S6, adding Ganoderma lucidum spore powder and Rehmannia glutinosa powder to the concentrated liquid medicine in proportion, stirring evenly, slowly adding white wine, stirring evenly, so that it is fully dissolved and mixed evenly; S7, heating the mixed solution to 80-90°C, sterilizing by heat preservation for 30 minutes, cooling to room temperature, filtering to remove impurities and suspended matter, and packaging the treated liquid into sterile oral liquid bottles and sealing; S8. Package the finished product and indicate the instructions for use, precautions and expiration date.

3. The processing technology of the deer placenta oral liquid according to claim 2, characterized in that: In the step S7, the mixed solution is heated to 85°C.

4. The processing technology of the deer placenta oral liquid according to claim 2, characterized in that: The heat preservation and extraction time in S4 is 2 hours.

5. The processing technology of the deer placenta oral liquid according to claim 2, characterized in that: During the S4-S7 process, attention should be paid to hygiene and cleanliness to prevent harmful microorganisms from contaminating the finished product.

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