Qi-invigorating and blood-nourishing oral liquid containing Chinese medicine composition and preparation process

Abstract

The invention discloses an oral liquid for invigorating qi and nourishing blood containing a traditional Chinese medicine composition, comprising the following raw materials in grams: 10-20g of ginseng, 40-80g of astragalus, 10-20g of codonopsis, 40-80g of ophiopogon, 30-60g of angelica, 50-100g of phellodendron, 30-60g of chicken gizzard lining, 40-80g of tuckahoe, 30-60g of cistanche, 20-40g of dodder seed, 20-40g of cyathula, 30-60g of roasted liquorice and 10-20g of longan pulp; the invention comprises the following steps: raw material preparation: ginseng, astragalus, codonopsis, ophiopogon , Chinese angelica, phellodendron, chicken gizzard lining, tuckahoe, cistanche, dodder seed, achyranthes bidentata, roasted licorice, longan pulp; extraction: the Chinese medicinal raw materials are crushed and decocted with water for extraction; the beneficial effects of the invention are: through the carefully selected Chinese medicinal raw materials and their proportions, a synergistic effect is achieved, and the efficacy is effectively improved; it can improve a series of symptoms caused by insufficient qi and blood, such as fatigue, pale complexion, dizziness, etc.; it has the effect of nourishing the kidney and stomach, and can improve the overall health of the patient; by strictly controlling the extraction, concentration, preparation and other steps, the quality stability of the oral liquid is guaranteed.

Description

Technical Field

[0001] The invention belongs to the technical field of qi-invigorating and blood-nourishing oral liquids, and in particular relates to a qi-invigorating and blood-nourishing oral liquid containing a traditional Chinese medicine composition and a preparation process. Background Art

[0002] Autumn and winter are traditional times for nourishing the body, and people generally hope to strengthen their physical fitness through food or medicine to lay a solid foundation for their health in the coming year; as a tonic Chinese patent medicine, Yiqi Yangxue oral liquid has the effect of nourishing qi and blood, which just meets this market demand; especially among the female group, problems such as insufficient qi and blood, physical weakness caused by work pressure, unbalanced diet or lifestyle are relatively common, so Yiqi Yangxue oral liquid has become an ideal choice; modern women drinking this oral solution can improve the body's hematopoietic function, improve blood quality, enhance the activity of blood cells, and prevent the occurrence of anemia; in addition, it can also effectively improve problems such as insufficient qi and blood and scanty menstruation; these significant therapeutic effects make Yiqi Yangxue oral liquid very popular in the market.

[0003] As an over-the-counter drug, Yiqi Yangxue Oral Liquid is relatively safe. Compared with other drugs, Yiqi Yangxue Oral Liquid has fewer side effects and is easy to take, which is one of the reasons for its popularity.

[0004] Patent publication number CN102119999A is a preparation method of a qi-invigorating and blood-nourishing oral liquid, which discloses the following steps: raw materials: 5.53g ginseng, 83.4g astragalus, 75g codonopsis, 50g ophiopogon, 33.3g angelica, 33.3g atractylodes, 33.3g rehmannia, 30g processed polygonum multiflorum, 25g schisandra, 33.3g tangerine peel, 25g lycium bark, 1.7g pilose antler, 50g epimedium; slice pilose antler, add water and boil twice, each time for 3 hours, combine the decoction, filter the filtrate and concentrate it to a paste with a relative density of 1.2 to 1.3, add 3 times the amount of ethanol, let it stand for 24 hours, filter it, and recover it. Ethanol and clear paste are set aside; take twelve herbs including Codonopsis pilosula, add water and boil twice, the first time for 3 hours, the second time for 2 hours, combine the decoctions, filter, concentrate to a relative density of 1.03-1.05, add deer antler extract and clear paste to dissolve; ultrafiltration through a 300,000 molecular weight ultrafiltration membrane, the drug solution temperature is 20-25℃, the ultrafiltration column inlet pressure is 1.2bar, the ultrafiltration column reflux pressure is 0.7bar, and the ultrafiltration column outlet pressure is 0.5bar; add sucrose 133g and refined honey 267g to the ultrafiltrate, heat and boil for 30min, cool, add auxiliary materials, adjust the total amount to 1000ml, stir evenly, filter, and fill.

[0005] There is still room for improvement in the formula and preparation process of the Qi-invigorating and blood-nourishing oral liquid currently on the market to further enhance its efficacy and applicability. Summary of the invention

[0006] The purpose of the present invention is to provide a qi-invigorating and blood-nourishing oral liquid containing a Chinese medicine composition and a preparation process. Through carefully selected Chinese medicine raw materials and their proportions, a synergistic effect is achieved, the balance of qi, blood, yin and yang is effectively promoted, the patient's immunity is improved, and at the same time, it has the effects of nourishing the kidney and stomach.

[0007] To achieve the above purpose, the present invention provides the following technical scheme: an oral liquid for invigorating qi and nourishing blood containing a traditional Chinese medicine composition, comprising the following raw materials in grams: 10-20g of ginseng, 40-80g of astragalus, 10-20g of codonopsis, 40-80g of ophiopogon, 30-60g of angelica, 50-100g of phellodendron, 30-60g of chicken gizzard lining, 40-80g of poria, 30-60g of cistanche, 20-40g of dodder seed, 20-40g of achyranthes bidentata, 30-60g of roasted licorice, and 10-20g of longan pulp.

[0008] As a preferred technical solution of the present invention, the invention comprises the following raw materials in grams by weight: 10g ginseng, 40g astragalus, 10g codonopsis, 40g ophiopogon, 30g angelica, 50g phellodendron, 30g chicken gizzard lining, 40g poria, 30g cistanche, 20g dodder seed, 20g achyranthes, 30g roasted licorice, and 10g longan pulp.

[0009] As a preferred technical solution of the present invention, the invention comprises the following raw materials in grams: 15g ginseng, 60g astragalus, 15g codonopsis, 60g ophiopogon, 45g angelica, 75g phellodendron, 45g chicken gizzard lining, 60g poria, 45g cistanche, 30g dodder seed, 30g achyranthes, 45g roasted licorice, and 15g longan pulp.

[0010] As a preferred technical solution of the present invention, the invention comprises the following raw materials in grams: 20g ginseng, 80g astragalus, 20g codonopsis, 80g ophiopogon, 60g angelica, 100g phellodendron, 60g chicken gizzard lining, 80g poria, 60g cistanche, 40g dodder seed, 40g achyranthes, 60g roasted licorice, and 20g longan pulp.

[0011] The present invention also discloses a preparation process of a Qi-invigorating and blood-nourishing oral liquid containing a Chinese medicine composition, comprising the following steps:

[0012] Raw materials: ginseng, astragalus, codonopsis, ophiopogon, angelica, phellodendron, chicken gizzard lining, tuckahoe, cistanche, dodder seed, cyathula, roasted licorice, longan pulp;

[0013] Extraction: crush the Chinese medicine raw materials, add water to boil and extract, extract twice, and combine the extracts;

[0014] Concentration: Concentrate the extract;

[0015] Preparation: Mix the concentrate with excipients to make the oral solution taste better and adjust the total amount to the required specifications;

[0016] Filtration and filling: Filter the prepared oral liquid to remove impurities, and then fill and seal it.

[0017] As a preferred technical solution of the present invention, water is added for decoction and extraction is performed twice, each time for 2-3 hours, and the extracts are combined.

[0018] As a preferred technical solution of the present invention, the extract is concentrated to a relative density of 1.05-1.10.

[0019] As a preferred technical solution of the present invention, the auxiliary materials are sucrose and refined honey.

[0020] Compared with the prior art, the present invention has the following beneficial effects:

[0021] Through the carefully selected Chinese medicinal raw materials and their proportions, synergistic effects are achieved, which effectively improves the efficacy; it can improve a series of symptoms caused by insufficient qi and blood, such as fatigue, pale complexion, dizziness, etc.

[0022] It has the effect of nourishing the kidneys and stomach, and can improve the patient's overall health;

[0023] By strictly controlling the extraction, concentration, and preparation steps, the quality of the oral liquid is guaranteed to be stable. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 The present invention is a flow chart of the preparation process of the Qi-invigorating and blood-nourishing oral liquid. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0026] Example 1

[0027] See also Figure 1 , is the first embodiment of the present invention, which provides a Qi-invigorating and blood-nourishing oral liquid containing a Chinese medicine composition, including the following raw materials in grams: 10g of ginseng, 40g of astragalus, 10g of codonopsis, 40g of ophiopogon, 30g of angelica, 50g of phellodendron, 30g of chicken gizzard lining, 40g of poria, 30g of cistanche, 20g of dodder seed, 20g of achyranthes bidentata, 30g of roasted licorice, and 10g of longan pulp.

[0028] A preparation process of a qi-invigorating and blood-nourishing oral liquid containing a Chinese medicine composition comprises the following steps:

[0029] Raw materials: ginseng, astragalus, codonopsis, ophiopogon, angelica, phellodendron, chicken gizzard lining, tuckahoe, cistanche, dodder seed, cyathula, roasted licorice, longan pulp;

[0030] Extraction: crush the raw materials of traditional Chinese medicine, add water to boil and extract, extract twice, each time for 2 hours, and combine the extracts;

[0031] Concentration: Concentrate the extract to a relative density of 1.05;

[0032] Preparation: The concentrate is prepared with auxiliary materials to make the oral liquid taste better, and the total amount is adjusted to the required specifications; the auxiliary materials are sucrose and refined honey;

[0033] Filtration and filling: Filter the prepared oral liquid to remove impurities, and then fill and seal it.

[0034] Ginseng can greatly replenish vital energy and is the first choice for treating internal injuries caused by asthenia. Ginseng alone can play a role in treating vital energy damage caused by heavy bleeding, sweating, vomiting, and diarrhea. It can enhance the spleen and stomach functions and improve symptoms such as fatigue, loss of appetite, and abdominal distension. It has the effects of promoting the production of body fluids and quenching thirst, as well as calming the mind and improving intelligence. It can be used to treat thirst caused by loss of body fluids, internal heat and thirst, and symptoms of qi and blood deficiency. It can regulate the balance between the excitation and inhibition processes of the central nervous system, improve work efficiency, and have an anti-fatigue effect. It can regulate the body's immune function and improve the body's resistance to a variety of pathogenic factors.

[0035] Astragalus is sweet and warm. It is a tonic medicine that is good at replenishing qi. Astragalus is a medicine that replenishes qi and consolidates the exterior. It is used for spontaneous sweating and fatigue caused by exterior deficiency. It is also used for edema caused by qi deficiency. Astragalus has the effects of diuresis, detoxification, sore astringence and tissue regeneration. It is used to strengthen the spleen and stomach and is used for qi deficiency symptoms. Astragalus can help sores and ulcers not heal after they have ruptured, and can heal sores and tissue regeneration. Astragalus can be used to treat internal heat and thirst.

[0036] Codonopsis can replenish the qi of the middle jiao and strengthen the spleen and stomach functions. It is suitable for the symptoms of spleen and lung qi deficiency, weakness in the limbs, and loss of appetite. It can not only nourish the spleen, but also benefit the lungs. It is suitable for the symptoms of spleen qi deficiency and lung qi deficiency. It can not only replenish qi, but also nourish blood and produce body fluid. It is suitable for diseases of qi and blood deficiency or qi and yin deficiency. It can improve the body's immune function and enhance the body's ability to resist diseases.

[0037] Ophiopogon japonicus can nourish yin and moisten the lungs, so it has a certain effect of moistening the lungs and relieving coughs for dry throat, dry cough, dry cough, and even hemoptysis caused by yin deficiency and lung dryness. It also has a certain effect of relieving throat pain, relieving drug-induced arrhythmia symptoms, or playing a sedative and blood sugar-lowering role. It is suitable for patients with yin deficiency and lung dryness, stomach yin deficiency, and heart yin deficiency, and can improve gastrointestinal discomfort and respiratory discomfort symptoms;

[0038] Angelica sinensis can significantly promote the body's hematopoietic function, increase the content of red blood cells, white blood cells and hemoglobin, and is suitable for many diseases caused by blood deficiency, such as sallow complexion, insomnia, palpitations, etc.; regulate menstruation and relieve pain; Angelica sinensis and its extracts have a significant stimulating effect on the mononuclear macrophage system, and have an immune regulation and recovery effect on the body with low immune function; Angelica sinensis also promotes the transformation of lymphocytes in healthy people, and at the same time enhances the body's immunity;

[0039] Huangbai is used for damp-heat diarrhea, with symptoms of yellow, sticky or pus-like vaginal discharge, or yellow water, vaginal itching, burning sensation, and short and red urine; it is used for damp-heat stranguria, with symptoms of frequent, short and astringent urination, dripping and stinging pain, lower abdominal cramps or waist and abdominal pain, etc.; it is used for damp-toxic swelling, eczema, mouth sores, furuncles, and scalds; Huangbai mainly enters the kidney meridian, is good at clearing away kidney deficiency fire, and has the effect of clearing away bone steaming, and can be used to treat yin deficiency and fire, bone steaming and hot flashes, spermatorrhea and night sweats, etc.; Huangbai has a broad-spectrum antibacterial effect, and is particularly strong in inhibiting various types of Shigella dysenteriae; Huangbai also has anti-influenza virus effect;

[0040] Chicken gizzard lining can digest food and eliminate stagnation, and can strengthen the spleen and stomach; it is suitable for treating symptoms such as abdominal distension, loss of appetite, vomiting and nausea caused by various food stagnation such as rice, noodles, potatoes, taro, milk, meat, etc.; it has the effects of consolidating semen, reducing urine, and stopping nocturnal emission, and can be used to treat nocturnal emission and other conditions; it is good at clearing stranguria and dissolving stones, and can treat gallbladder distension and flank pain, etc.

[0041] Poria has a sweet and mild taste and a mild medicinal property. It can promote diuresis and eliminate dampness. Therefore, it can be used to treat various edemas caused by cold, heat, deficiency or excess, and urination problems. Poria can strengthen the spleen and eliminate dampness, so that dampness has nowhere to accumulate and phlegm has no reason to be produced. It can be used to treat dizziness caused by phlegm and fluid, palpitations and restlessness, etc. Poria has a sweet taste and enters the spleen meridian. It can strengthen the spleen and replenish the middle, eliminate dampness and stop diarrhea, and make the middle jiao clear and the turbid rise and fall. Therefore, it can be used to treat poor appetite, fatigue, loose stools and diarrhea caused by spleen deficiency and dampness. Therefore, it can be used to treat restlessness, palpitations and insomnia caused by deficiency of the heart and spleen. Poria has the functions of regulating immunity and protecting the liver. It can be used to treat poor appetite, fatigue, loose stools and diarrhea caused by spleen deficiency and dampness. Poria has a sedative effect and can be used to treat restlessness, palpitations and insomnia.

[0042] Cistanche deserticola has a strong kidney-tonifying effect, can improve the synthesis of DNA in yang-deficient organisms, improve protein nucleic acid metabolism, and improve kidney function; Cistanche deserticola can improve sperm production and vitality, promote sperm reproduction ability, and increase male reproductive function; Cistanche deserticola contains a large amount of biologically active substances, which can increase the weight of the spleen and thymus, and can significantly enhance the activity of phagocytes, and has a strong enhancing effect on humoral immunity;

[0043] Cuscuta can be used clinically to treat symptoms such as liver and kidney deficiency, soreness of waist and knees, impotence and spermatorrhea, enuresis and frequent urination, kidney deficiency and fetal leakage, fetal movement disorder, blurred vision and tinnitus, spleen deficiency and diarrhea; Cuscuta can also enhance the body's yang energy, improve the body's immunity, improve the body's endocrine system, and regulate heart rate and blood pressure.

[0044] The nature and flavor of Achyranthes bidentata is bitter, sour and flat; it belongs to the liver and kidney meridians, and its effects are to promote blood circulation and remove blood stasis, nourish the liver and kidney, and strengthen the tendons and bones; if it is used for the therapeutic effect of nourishing the liver and kidney and strengthening the tendons and bones, it can treat soreness of waist and knees and fatigue, especially for modern patients with severe osteoarthritis of both knees and lumbar disc herniation, it has a relatively good effect of nourishing the liver and kidney and strengthening the tendons and bones; it also has the effect of diuresis and stranguria, and has a good effect on patients with hematuria and urination pain, because Achyranthes bidentata is good at descending, so it can lead the medicine downward to treat urinary tract infection;

[0045] Roasted licorice root is flat in nature, sweet in taste, and enters the heart, lung, spleen, and stomach meridians. Its effects and functions are as follows: tonifying the spleen and stomach, replenishing qi and restoring pulse: Roasted licorice root has the effects of tonifying the spleen and stomach, replenishing qi and restoring pulse. It can be used for spleen and stomach weakness, fatigue, palpitations and shortness of breath, cough with sputum, abdominal pain, carbuncle, sore, food poisoning, etc.

[0046] Longan meat is sweet and warm in nature. It belongs to the heart and spleen meridians. It can nourish the heart and spleen, nourish blood and calm the mind. Studies have found that it has high nutritional value because it is rich in carbohydrates, protein, multiple amino acids and vitamins B and C, as well as calcium, phosphorus, iron, etc.

[0047] Example 2

[0048] See also Figure 1 , which is the second embodiment of the present invention, is based on the previous embodiment, except that:

[0049] A qi-invigorating and blood-nourishing oral liquid containing a traditional Chinese medicine composition comprises the following raw materials in grams: 15g ginseng, 60g astragalus, 15g codonopsis, 60g ophiopogon, 45g angelica, 75g phellodendron, 45g chicken gizzard lining, 60g tuckahoe, 45g cistanche, 30g dodder seed, 30g achyranthes, 45g roasted liquorice, and 15g longan pulp.

[0050] Extraction: crush the raw materials of traditional Chinese medicine, add water to boil and extract, extract twice, each time for 2.5 hours, and combine the extracts;

[0051] Concentration: Concentrate the extract to a relative density of 1.08.

[0052] Example 3

[0053] See also Figure 1 , which is the third embodiment of the present invention, is based on the previous embodiment, except that:

[0054] A qi-invigorating and blood-nourishing oral liquid containing a traditional Chinese medicine composition comprises the following raw materials in grams: 20g of ginseng, 80g of astragalus, 20g of codonopsis, 80g of ophiopogon, 60g of angelica, 100g of phellodendron, 60g of chicken gizzard lining, 80g of tuckahoe, 60g of cistanche, 40g of dodder seed, 40g of achyranthes, 60g of roasted liquorice, and 20g of longan pulp.

[0055] Extraction: crush the raw materials of traditional Chinese medicine, add water to boil and extract, extract twice, each time for 3 hours, and combine the extracts;

[0056] Concentration: Concentrate the extract to a relative density of 1.10.

[0057] Clinical trials

[0058] Clinical data: 100 patients with shortness of breath, palpitations, sallow complexion, and physical weakness, aged 42-52 years;

[0059] Treatment method: Oral; three times a day; 10-15ml each time; 2 months as a course of treatment;

[0060] Efficacy evaluation criteria:

[0061] Marked effect: limbs became stronger, physical fitness was significantly enhanced, complexion and energy were improved, and the improvement was obvious; 60 people showed marked effect;

[0062] Effective: limbs are stronger, physical fitness is improved, energy is abundant, complexion is improved; effective number of people: 30;

[0063] Ineffective: No improvement was found in symptoms and various examinations, and 10 people had ineffective results.

[0064] Although the embodiments of the present invention have been shown and described, as detailed above, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An oral liquid for replenishing qi and nourishing blood containing a Chinese medicine composition, characterized in that: The invention comprises the following raw materials in grams: 10-20g ginseng, 40-80g astragalus, 10-20g codonopsis, 40-80g ophiopogon, 30-60g angelica, 50-100g phellodendron, 30-60g chicken gizzard lining, 40-80g poria, 30-60g cistanche, 20-40g dodder seed, 20-40g achyranthes, 30-60g roasted licorice, and 10-20g longan pulp.

2. The Qi-invigorating and blood-nourishing oral liquid containing a Chinese medicine composition according to claim 1, characterized in that: The invention comprises the following raw materials in grams: 10g ginseng, 40g astragalus, 10g codonopsis, 40g ophiopogon, 30g angelica, 50g phellodendron, 30g chicken gizzard lining, 40g poria, 30g cistanche, 20g dodder seed, 20g achyranthes, 30g roasted licorice, and 10g longan pulp.

3. The Qi-invigorating and blood-nourishing oral liquid containing a Chinese medicine composition according to claim 1, characterized in that: The invention comprises the following raw materials in grams: 15g ginseng, 60g astragalus, 15g codonopsis, 60g ophiopogon, 45g angelica, 75g phellodendron, 45g chicken gizzard lining, 60g poria, 45g cistanche, 30g dodder seed, 30g achyranthes bidentata, 45g roasted licorice root and 15g longan pulp.

4. The Qi-invigorating and blood-nourishing oral liquid containing a Chinese medicine composition according to claim 1, characterized in that: The invention comprises the following raw materials in grams: 20g ginseng, 80g astragalus, 20g codonopsis, 80g ophiopogon, 60g angelica, 100g phellodendron, 60g chicken gizzard lining, 80g poria, 60g cistanche, 40g dodder seed, 40g achyranthes, 60g roasted licorice, and 20g longan pulp.

5. The preparation process of the Qi-invigorating and blood-nourishing oral liquid containing a Chinese medicine composition according to any one of claims 1 to 4, characterized in that: The steps include: Raw materials: ginseng, astragalus, codonopsis, ophiopogon, angelica, phellodendron, chicken gizzard lining, tuckahoe, cistanche, dodder seed, cyathula, roasted licorice, longan pulp; Extraction: crush the Chinese medicine raw materials, add water to boil and extract, extract twice, and combine the extracts; Concentration: Concentrate the extract; Preparation: Mix the concentrate with excipients to make the oral solution taste better and adjust the total amount to the required specifications; Filtration and filling: Filter the prepared oral liquid to remove impurities, and then fill and seal it.

6. The preparation process of the Qi-invigorating and blood-nourishing oral liquid containing a Chinese medicine composition according to claim 5, characterized in that: Add water and boil to extract, extract twice, each time for 2-3 hours, and combine the extracts.

7. The preparation process of the Qi-invigorating and blood-nourishing oral liquid containing a Chinese medicine composition according to claim 5, characterized in that: The extract is concentrated to a relative density of 1.05-1.

10.

8. The preparation process of the Qi-invigorating and blood-nourishing oral liquid containing a Chinese medicine composition according to claim 5, characterized in that: The auxiliary materials are sucrose and refined honey.

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