Repairing composition, repairing face cream and application of repairing composition and repairing face cream

Abstract

The invention relates to a repairing composition, repairing cream and application thereof, and belongs to the technical field of cosmetics. The repairing composition is prepared from allantoin, acetylated sodium hyaluronate, cetyl-PG hydroxyethyl palmitamide, an anti-allergy agent and hydrosol; wherein the anti-allergy agent comprises octyldodecanol, plantain herb seed oil, sunflower seed oil unsaponifiable matter, a cardiospermum halicacabum flower / leaf / vine extract and tocopherol; the hydrosol comprises water, glycerin, sodium dihydrogen phosphate, disodium hydrogen phosphate and soluble collagen. The skin barrier can be effectively improved, the percutaneous moisture loss is reduced, and the obvious repairing effect is achieved.

Description

Technical Field

[0001] The present application relates to the technical field of cosmetics, and in particular to a repairing composition, a repairing cream and applications thereof. Background Art

[0002] The skin is the largest organ covering the human body. It plays an important role in resisting harmful external environments and protecting the body's health. The integrity of its structure and normal function are extremely critical to maintaining human health. In recent years, with the influence of changes in the external natural environment and the excessive pursuit of functional skin care concepts, more and more consumers have experienced certain skin barrier damage. Damage to the skin barrier can cause symptoms such as burning, stinging, itching, scaling, tightness, and easy redness. If it persists for a long time, it will evolve into sensitive skin and even induce inflammatory skin diseases such as atopic dermatitis.

[0003] Currently, ceramide is often used in combination with other components to soothe and repair the skin. However, ceramide can only provide exogenous moisturizing effect and is expensive. It is usually added in low amounts and has weak soothing and repairing effects on the skin. Summary of the invention

[0004] In view of the deficiencies of the prior art, the purpose of the embodiments of the present application includes providing a repair composition, a repair cream and their application, which can effectively improve the skin barrier, reduce transepidermal water loss and have significant repair effects.

[0005] In the first aspect, the embodiments of the present application provide a repair composition, which includes: allantoin, acetylated sodium hyaluronate, cetyl-PG hydroxyethyl palmitamide, an anti-allergic agent, and a hydrosol; wherein the anti-allergic agent includes octyldodecanol, echium plantaginis seed oil, unsaponifiable matter of sunflower seed oil, bellflower flower / leaf / vine extract, and tocopherol; the hydrosol includes water, glycerin, sodium dihydrogen phosphate, disodium hydrogen phosphate, and soluble collagen.

[0006] The cetyl-PG hydroxyethyl palmitamide used in this application is a ceramide-like substance with the same efficacy as ceramide, but is cheaper. On the basis of providing exogenous moisturizing effect, it is compounded with allantoin, acetylated sodium hyaluronate, anti-allergic agent and hydrosol, and the anti-allergic agent includes octyldodecanol, echium plantaginis seed oil, unsaponifiable matter of sunflower seed oil, cymbidium flower / leaf / vine extract and tocopherol; the hydrosol includes water, glycerin, sodium dihydrogen phosphate, sodium hydrogen phosphate and soluble collagen, which can simultaneously promote the proliferation of epidermal cells, repair damaged epidermal cells, calm and protect irritated sensitive skin, replenish skin collagen, thereby effectively improving the skin barrier, reducing transepidermal water loss, and having a significant repair effect.

[0007] In some embodiments of the present application, the repair composition includes, by weight: 0.05-0.3 parts of allantoin, 0.01-0.1 parts of acetylated sodium hyaluronate, 0.1-2 parts of cetyl-PG hydroxyethyl palmitamide, 0.5-5 parts of anti-allergic agent, and 0.1-5 parts of hydrosol.

[0008] The present application further adopts allantoin, acetylated sodium hyaluronate, cetyl-PG hydroxyethyl palmitamide, anti-allergic agent and hydrosol in appropriate proportions to further synergistically improve the skin barrier and more significantly repair the skin.

[0009] In the second aspect, an embodiment of the present application provides a repair composition, which is composed of 0.05-0.3 parts of allantoin, 0.01-0.1 parts of acetylated sodium hyaluronate, 0.1-2 parts of cetyl-PG hydroxyethyl palmitamide, 0.5-5 parts of anti-allergic agents and 0.1-5 parts of hydrosol; wherein the anti-allergic agent is composed of octyldodecanol, echium plantaginis seed oil, unsaponifiable matter of sunflower seed oil, bellflower flower / leaf / vine extract and tocopherol; the hydrosol is composed of water, glycerin, sodium dihydrogen phosphate, disodium hydrogen phosphate and soluble collagen.

[0010] This application only uses cetyl-PG hydroxyethyl palmitamide and allantoin, acetylated sodium hyaluronate, anti-allergic agent, and hydrosol. The anti-allergic agent is composed of octyldodecanol, Echium plantain seed oil, unsaponifiable matter of sunflower seed oil, Bellflower flower / leaf / vine extract and tocopherol; the hydrosol is composed of water, glycerin, sodium dihydrogen phosphate, disodium hydrogen phosphate and soluble collagen. On the basis of providing exogenous moisturizing effect, it also promotes epidermal cell proliferation, repairs damaged epidermal cells, calms and protects irritated sensitive skin, replenishes skin collagen, thereby effectively improving the skin barrier, reducing transepidermal water loss, and has a significant repair effect.

[0011] In a third aspect, an embodiment of the present application provides a use of a repair composition as provided in the first aspect or the second aspect in the preparation of cosmetics or medicines with repair effects.

[0012] The present application adopts the above-mentioned repair composition to prepare cosmetics or medicines. Since the above-mentioned repair composition can effectively improve the skin barrier, reduce transepidermal water loss, and has significant repair effects, the cosmetics or medicines prepared using the repair composition also have a more obvious enhancement of the skin barrier and a more significant repair effect.

[0013] In a fourth aspect, an embodiment of the present application provides a repairing facial cream, comprising the repairing composition provided in the first aspect or the second aspect; the mass percentage of the repairing composition in the repairing facial cream is 0.76%-12.4%.

[0014] The repairing facial cream provided in the present application includes the above-mentioned repairing composition in an appropriate mass percentage. Since the above-mentioned repairing composition can effectively improve the skin barrier, reduce transepidermal water loss, and has a significant repairing effect, the repairing facial cream including the repairing composition also has a more obvious enhancement of the skin barrier and a more significant repairing effect.

[0015] In some embodiments of the present application, the repairing facial cream includes a skin softener, a skin softening powder, an emulsifier and solid oils; wherein the skin softener includes hydrogenated coconut glycerides and jojoba esters; and the skin softening powder includes lauroyl lysine and cetyl palmitate.

[0016] The present application adopts the use of softening agents, softening powders, emulsifiers and solid oils in the repairing cream, and the softening agents are hydrogenated coconut glycerides and jojoba esters; the softening powders are lauroyl lysine and cetyl palmitate, which can make the cream have a firm texture, melt quickly on the hands, and be smooth during application. Continuous application of the cream will gradually break the emulsion and release the oil phase, and it has the characteristics of moisturizing and has a unique multiple skin feel experience.

[0017] In some embodiments of the present application, the emulsifier includes cetearyl alcohol, steareth-21 and glyceryl stearate.

[0018] This application adopts cetearyl alcohol, steareth-21 and glyceryl stearate as emulsifiers, and is combined with the above-mentioned softeners, softening powders and solid oils to further make the cream moisturizing. It melts quickly on the hands and is smooth during application. Continuous application of the paste will gradually break the emulsion and release the oil phase.

[0019] In some embodiments of the present application, the solid fat includes white beeswax.

[0020] The present application selects white beeswax as the solid oil, which is combined with the above-mentioned softener, softening powder and emulsifier to further make the cream have the characteristic of a firm texture.

[0021] In some embodiments of the present application, the repairing facial cream further comprises auxiliary materials, and the auxiliary materials comprise at least one of moisturizing agents, thickeners, emollients, emollients, antioxidants, protective agents, preservatives, fragrances, and colorants.

[0022] The present application adopts at least one of the above-mentioned auxiliary materials, in combination with the above-mentioned repair composition, softener, softening powder, emulsifier and solid oil, to form a facial cream that has both repairing effect and moisturizing characteristics, and a unique multiple skin feel experience.

[0023] In a fifth aspect, the embodiment of the present application provides a repairing facial cream, which includes, by mass percentage: 0.05%-0.3% allantoin, 0.01%-0.1% acetylated sodium hyaluronate, 0.1%-2% cetyl-PG hydroxyethyl palmitamide, 0.5%-5% anti-allergic agent, 0.1%-5% hydrosol, 1%-2.5% hydrogenated coconut glycerides, 1%-2.5% jojoba esters, 0.5%-3% lauroyl lysine, and 0.5%-3% cetyl palmitamide. Palmitate 0.5%-1.5%, cetearyl alcohol 1.75%-3.25%, steareth-21 0.8%-1.5%, glyceryl stearate 1.5%-2.5%, white beeswax 0.5%-2%; the rest is water; among them, the anti-allergic agents include octyldodecanol, echium plantaginis seed oil, unsaponifiable matter of sunflower seed oil, bellflower flower / leaf / vine extract and tocopherol; the hydrosol includes water, glycerin, sodium dihydrogen phosphate, disodium hydrogen phosphate and soluble collagen.

[0024] The repairing facial cream provided in the present application comprises a repairing composition, a softening agent, a softening powder, an emulsifier and solid oils in appropriate mass percentages, thereby forming a facial cream that has both significant repairing effects and moisturizing characteristics, and a unique multiple skin feel experience.

[0025] In some embodiments of the present application, the repairing facial cream further comprises 20.4%-59.9% by weight of auxiliary materials.

[0026] The present application adopts an appropriate mass percentage of auxiliary materials, combined with an appropriate mass percentage of a repair composition, a softener, a softening powder, an emulsifier and solid oils, to form a facial cream that has both significant repair effects and moisturizing characteristics, and a unique multiple skin feel experience. DETAILED DESCRIPTION

[0027] In order to make the purpose, technical scheme and advantages of the embodiments of the present application clearer, the technical scheme in the embodiments of the present application will be described clearly and completely below. If the specific conditions are not specified in the embodiments, they are carried out according to the conventional conditions or the conditions recommended by the manufacturer. If the manufacturer is not specified for the reagents or instruments used, they are all conventional products that can be purchased commercially.

[0028] An embodiment of the present application provides a repair composition, which includes: allantoin, acetylated sodium hyaluronate, cetyl-PG hydroxyethyl palmitamide, an anti-allergic agent, and a hydrosol; wherein the anti-allergic agent includes octyldodecanol, echium plantaginis seed oil, unsaponifiable matter of sunflower seed oil, bellflower flower / leaf / vine extract, and tocopherol; the hydrosol includes water, glycerin, sodium dihydrogen phosphate, disodium hydrogen phosphate, and soluble collagen.

[0029] The cetyl-PG hydroxyethyl palmitamide used in this application is a ceramide-like compound, which has the same efficacy as ceramide, but is cheaper. On the basis of providing exogenous moisturizing effect, it is compounded with allantoin, acetylated sodium hyaluronate, anti-sensitizer and hydrosol, and the anti-sensitizer includes octyldodecanol, echium plantaginis seed oil, unsaponifiable matter of sunflower seed oil, cymbidium flower / leaf / vine extract and tocopherol; the hydrosol includes water, glycerin, sodium dihydrogen phosphate, sodium dihydrogen phosphate and soluble collagen; among them, allantoin is an amphoteric compound that can combine with multiple substances to form complex salts, has light-shielding, bactericidal and antiseptic, analgesic and antioxidant effects, and has the effect of promoting skin , the water absorption capacity of the outermost layer of hair tissue, and enhance the ability of keratinocytes to bind water; acetylated sodium hyaluronate can bring lipophilicity, promote epidermal cell proliferation, and repair damaged epidermal cells; anti-allergic agents are rich in unsaturated fatty acids (linolenic acid) and have a high content of unsaponifiable oils (phytosterols, vitamin E and squalene), which can calm and protect irritated sensitive skin, consolidate and strengthen the skin barrier, and have a strong regenerative ability for the skin barrier; hydrosols can replenish skin collagen and enhance the skin barrier; thereby, through the synergistic effect of water solubility and oil solubility, it can more effectively improve the skin barrier, reduce transepidermal water loss, and has a significant repair effect.

[0030] In some embodiments of the present application, the repair composition includes by weight: 0.05-0.3 parts of allantoin, 0.01-0.1 parts of acetylated sodium hyaluronate, 0.1-2 parts of cetyl-PG hydroxyethyl palmitamide, 0.5-5 parts of anti-allergic agent, and 0.1-5 parts of hydrosol. Further using allantoin, acetylated sodium hyaluronate, cetyl-PG hydroxyethyl palmitamide, anti-allergic agent and hydrosol in appropriate proportions, the skin barrier is further synergistically improved, and the skin is repaired more significantly.

[0031] An embodiment of the present application provides a repair composition, which consists of 0.05-0.3 parts of allantoin, 0.01-0.1 parts of acetylated sodium hyaluronate, 0.1-2 parts of cetyl-PG hydroxyethyl palmitamide, 0.5-5 parts of an anti-allergic agent and 0.1-5 parts of a hydrosol; wherein the anti-allergic agent consists of octyldodecanol, echium plantaginis seed oil, unsaponifiable matter of sunflower seed oil, bellflower flower / leaf / vine extract and tocopherol; the hydrosol consists of water, glycerin, sodium dihydrogen phosphate, sodium dihydrogen phosphate and soluble collagen.

[0032] As an example, the allantoin in the repair composition can be, but is not limited to, 0.05, 0.08, 0.1, 0.12, 0.15, 0.18, 0.2, 0.22, 0.25, 0.28, 0.3. The acetylated sodium hyaluronate can be, but is not limited to, 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.1. The cetyl-PG hydroxyethyl palmitamide can be, but is not limited to, 0.1, 0.3, 0.5, 0.8, 1, 1.3, 1.5, 1.8, 2. The anti-allergic agent can be, but is not limited to, 0.5, 0.8, 1, 1.2, 1.5, 1.8, 2, 2.5, 3, 3.5, 4, 4.5, or 5. The hydrosol can be, but is not limited to, 0.1, 0.5, 0.8, 1, 1.2, 1.5, 1.8, 2, 2.5, 3, 3.5, 4, 4.5, or 5.

[0033] As an example, the anti-sensitizer is , purchased from RAHN AG. Octyldodecanol, Echium plantaine seed oil, unsaponifiable matter of sunflower seed oil, Cyperus rotundus flower / leaf / vine extract and tocopherol can also be used for preparation. The hydrosol is HydroCol-y, purchased from Best Pharmaceutical (Guangzhou) Co., Ltd. Water, glycerin, sodium dihydrogen phosphate, sodium dihydrogen phosphate and soluble collagen can also be used for preparation.

[0034] This application only uses cetyl-PG hydroxyethyl palmitamide and allantoin, acetylated sodium hyaluronate, anti-allergic agent, and hydrosol. The anti-allergic agent is composed of octyldodecanol, Echium plantain seed oil, unsaponifiable matter of sunflower seed oil, Bellflower flower / leaf / vine extract and tocopherol; the hydrosol is composed of water, glycerin, sodium dihydrogen phosphate, disodium hydrogen phosphate and soluble collagen. On the basis of providing exogenous moisturizing effect, it also promotes epidermal cell proliferation, repairs damaged epidermal cells, calms and protects irritated sensitive skin, replenishes skin collagen, thereby effectively improving the skin barrier, reducing transepidermal water loss, and has a significant repair effect.

[0035] The embodiments of the present application provide a use of the above-mentioned repair composition in the preparation of cosmetics or medicines with repair effects.

[0036] The present application adopts the above-mentioned repair composition to prepare cosmetics or medicines. Since the above-mentioned repair composition can effectively improve the skin barrier, reduce transepidermal water loss, and has significant repair effects, the cosmetics or medicines prepared using the repair composition also have a more obvious enhancement of the skin barrier and a more significant repair effect.

[0037] The embodiment of the present application provides a repairing facial cream, comprising the above-mentioned repairing composition; the mass percentage of the repairing composition in the repairing facial cream is 0.76%-12.4%.

[0038] As an example, the mass percentage of the repair composition in the repair cream can be but is not limited to 0.76%, 0.8%, 0.95%, 1%, 2.5%, 3%, 5%, 6.5%, 8%, 9.5%, 10%, 11%, 12%, and 12.4%.

[0039] The repairing facial cream provided in the present application includes the above-mentioned repairing composition in an appropriate mass percentage. Since the above-mentioned repairing composition can effectively improve the skin barrier, reduce transepidermal water loss, and has a significant repairing effect, the repairing facial cream including the repairing composition also has a more obvious enhancement of the skin barrier and a more significant repairing effect.

[0040] In some embodiments of the present application, the repairing cream includes a skin softener, a skin softening powder, an emulsifier and a solid oil; wherein the skin softener includes hydrogenated coconut glycerides and jojoba esters; and the skin softening powder includes lauroyl lysine and cetyl palmitate. The skin softener, skin softening powder, emulsifier and solid oil are used in combination in the repairing cream, and the skin softener is selected from hydrogenated coconut glycerides and jojoba esters; the skin softening powder is selected from lauroyl lysine and cetyl palmitate, so that the cream has a firm texture, melts quickly on the hands, is smooth during application, and continues to apply the cream to gradually demulsify and release the oil phase, which has the characteristics of moisturizing and has a unique multiple skin feel experience.

[0041] In some embodiments of the present application, the emulsifier includes cetearyl alcohol, steareth-21 and glyceryl stearate. The emulsifiers, cetearyl alcohol, steareth-21 and glyceryl stearate are used together with the above-mentioned softener, softener powder and solid oil to further make the cream moisturizing, melt quickly, smooth during application, and gradually break the emulsion and release the oil phase.

[0042] In some embodiments of the present application, the solid fat includes white beeswax. The white beeswax is selected as the solid fat, and combined with the above-mentioned softener, softening powder and emulsifier, the facial cream further has the characteristic of a firm texture.

[0043] In some embodiments of the present application, the repairing cream further comprises auxiliary materials, and the auxiliary materials include at least one of moisturizers, thickeners, emollients, softeners, antioxidants, protective agents, preservatives, fragrances, and colorants. The at least one auxiliary material mentioned above is used in combination with the repairing composition, softener, softening powder, emulsifier, and solid oil to form a cream that has both repairing effects and moisturizing characteristics, and a unique multi-skin feel experience.

[0044] The present application provides a repairing facial cream, which comprises, by mass percentage, 0.05%-0.3% allantoin, 0.01%-0.1% acetylated sodium hyaluronate, 0.1%-2% cetyl-PG hydroxyethyl palmitamide, 0.5%-5% anti-allergic agent, 0.1%-5% hydrosol, 1%-2.5% hydrogenated coconut glycerides, 1%-2.5% jojoba esters, 0.5%-3% lauroyl lysine, and cetyl palmitic acid. Esters 0.5%-1.5%, cetearyl alcohol 1.75%-3.25%, steareth-21 0.8%-1.5%, glyceryl stearate 1.5%-2.5%, white beeswax 0.5%-2%; the rest is water; among them, the anti-allergic agents include octyldodecanol, echium plantago seed oil, unsaponifiable matter of sunflower seed oil, bellflower flower / leaf / vine extract and tocopherol; the hydrosol includes water, glycerin, sodium dihydrogen phosphate, disodium hydrogen phosphate and soluble collagen.

[0045] The repairing facial cream provided in the present application comprises a repairing composition, a softening agent, a softening powder, an emulsifier and solid oils in appropriate mass percentages, thereby forming a facial cream that has both significant repairing effects and moisturizing characteristics, and a unique multiple skin feel experience.

[0046] In some embodiments of the present application, the repairing cream further comprises 20.4%-59.9% by weight of auxiliary materials. The auxiliary materials of appropriate weight percentage are combined with appropriate weight percentages of the repairing composition, softener, softening powder, emulsifier and solid oil to form a cream with significant repairing effect, moisturizing characteristics and unique multiple skin feeling experience.

[0047] As an example, the formula of the repairing cream is shown in Table 1.

[0048] Table 1 Formula of repairing cream

[0049]

[0050]

[0051]

[0052] The features and performance of the present application are further described in detail below in conjunction with the embodiments.

[0053] Example 1

[0054] This embodiment provides a repairing facial cream, and the specific formula of the repairing facial cream is shown in Table 2:

[0055] Table 2 Formula of repairing cream

[0056]

[0057]

[0058]

[0059] This embodiment provides a method for preparing a repairing facial cream, comprising:

[0060] (1) Add No. 31 and No. 32 to No. 33 in proportion, and disperse evenly with an external homogenizer until there is no granular preformed raw material (A) for later use;

[0061] (2) Adding raw material No. 1 to the water phase pot in proportion, stirring at 1000 rpm, adding raw materials No. 2, No. 3, No. 4, No. 5, No. 6, No. 7, No. 8 and No. 9, heating to 95°C, and keeping warm for 20 minutes;

[0062] (3) Add No. 10, No. 11, No. 12, No. 13, No. 14, No. 15, No. 16, No. 17, No. 18, No. 19, No. 20, No. 21, No. 22, No. 23, No. 24 and No. 25 raw materials into the oil phase pot in proportion, start stirring at 1000 rpm, raise the temperature to 95° C., and keep warm for 15 minutes;

[0063] (4) Pump 3 / 4 of the water phase pot material into the emulsification pot, start the emulsification pot with maximum stirring, pump the oil phase pot material into the emulsification pot, and then pump the remaining 1 / 4 of the water phase pot material into the emulsification pot, vacuumize to -0.05Mpa, start external circulation homogenization for 8 minutes at 3000rpm. After homogenization is completed, add raw material No. 26 and start cooling;

[0064] (5) Reduce the stirring speed to 55 rpm, and when the temperature drops to 40°C, add No. 27, No. 28, No. 29, No. 30 and pre-made raw material (A), No. 34, and No. 35, and keep stirring under vacuum for 15 minutes;

[0065] (6) After the samples are tested and found to be qualified, filter the material with a 100-mesh filter cloth at 38°C.

[0066] Example 2

[0067] This embodiment provides a repairing facial cream, and the specific formula of the repairing facial cream is shown in Table 3:

[0068] Table 3 Formula of repairing cream

[0069]

[0070]

[0071] The preparation method of a repairing facial cream provided in this embodiment is the same as the preparation method in Example 1.

[0072] Comparative Example 1

[0073] This embodiment provides a facial cream, which is different from Embodiment 2 in that components No. 8, No. 9, No. 24, No. 34 and No. 35 (see Table 3) in the formula of the repairing facial cream of Embodiment 2 are not included.

[0074] Comparative Example 2

[0075] This embodiment provides a facial cream, which is different from the embodiment 2 in that: 0.01% by mass of hydrolyzed sodium hyaluronate (nano Enzyme-cleaved oligomeric sodium hyaluronate, purchased from Bloomage Biotechnology Co., Ltd.) and 0.1% by weight of Relipidium TM BC10096 (composed of hydrolyzed yeast protein, butanediol, and 1,2-pentanediol, purchased from BASF (China) Co., Ltd.).

[0076] Comparative Example 3

[0077] This embodiment provides a facial cream, which is different from embodiment 2 in that: EDELWEISS CB (composed of alpine edelweiss flower / leaf extract, glycerin, water, citric acid, purchased from DSM Nutritional Products Ltd.) (composed of octyldodecanol, echium plantaginis seed oil, unsaponifiable matter of sunflower seed oil, Cyperus rotundus flower / leaf / vine extract, tocopherol, purchased from RAHN AG), phytosphingosine was used instead of cetyl-PG hydroxyethyl palmitamide, and the mass percentage remained unchanged.

[0078] Comparative Example 4

[0079] This embodiment provides a facial cream, which is different from Embodiment 2 in that components No. 8, No. 9, No. 24, No. 34 and No. 35 in the formula of the repairing facial cream of Embodiment 2 are replaced with 0.76% by mass of cetyl-PG hydroxyethyl palmitamide.

[0080] Comparative Example 5

[0081] This embodiment provides a facial cream, which is different from Example 2 in that components No. 8, No. 9, No. 24, No. 34 and No. 35 in the formula of the repairing facial cream of Example 2 are replaced with 0.66% by mass of cetyl-PG hydroxyethyl palmitamide and 0.1% by mass of allantoin.

[0082] Comparative Example 6

[0083] This embodiment provides a facial cream, which is different from the embodiment 2 in that the components No. 8, No. 9, No. 24, No. 34 and No. 35 in the formula of the repairing facial cream of the embodiment 2 are replaced by 0.21% by mass of cetyl-PG hydroxyethyl palmitamide, 0.05% by mass of allantoin and 0.5% by mass of (Composed of octyldodecanol, Echium plantain seed oil, unsaponifiable matter of sunflower seed oil, Cyperus rotundus flower / leaf / vine extract, tocopherol).

[0084] Comparative Example 7

[0085] This embodiment provides a facial cream, which is different from Embodiment 2 in that the hydrogenated coconut glycerides in the formula of the repairing facial cream of Embodiment 2 are replaced by stearic acid, and lauroyl lysine is replaced by polymethyl silsesquioxane, and the mass percentages remain unchanged.

[0086] Test Example 1

[0087] This test example performs a patch test on the repairing facial cream provided in Example 1, and the specific method is as follows:

[0088] Take 0.020-0.025mL of the repairing cream provided in Example 1 and place it in a patch device, apply it to the inner side of the subject's arm with a hypoallergenic tape, remove the test substance after 24 hours, and observe the skin reaction after 0.5 hours, 24 hours and 48 hours respectively; the blank control directly uses an empty patch device. Record the results according to the skin reaction grading standard in the human patch test in Chapter 7 of the 2015 edition of the "Technical Specifications for Safety of Cosmetics". There are 30 subjects (1 male and 29 females, aged between 20 and 60 years old). The skin reaction grading standard is shown in Table 4. The patch test results are shown in Table 5.

[0089] Table 4 Skin reaction grading standards

[0090]

[0091]

[0092] Table 5 Patch test results

[0093]

[0094] As shown in Table 5, each component in the repairing cream in Example 1 is added at the maximum amount, and the patch test shows that the scores of 30 subjects after removing the test patch tester for 0.5h, 24h, and 48h are all 0. The scores of negative control patch testers after removing the negative control patch tester for 0.5h, 24h, and 48h are all 0. This shows that the repairing cream provided by the present application is mild and non-irritating.

[0095] Test Example 2

[0096] This test example tests the efficacy of the creams provided in Examples 1-2 and Comparative Examples 1-6, and the specific method is as follows:

[0097] The subjects randomly used the repairing cream provided in Example 1-2 on one side of the inner side of the left and right arms for 21 consecutive days, and used the cream provided in Comparative Example 1-6 on the other side (the return visit time is allowed to be adjusted to 1 day before and after). Return visits were made before the trial (D0) and 21 days after the trial (D21), and the water content of the stratum corneum of the inner side of the random arm was tested and the transepidermal water loss rate (TEWL) was calculated. The transepidermal water loss rate (%) = the difference in water loss before and after / the water loss before * 100; the test results before and after using the product were compared to see if there were statistical differences. The results are shown in Table 6.

[0098] Table 6 Repairing cream efficacy test results

[0099] Test samples Testing time Transepidermal water loss rate (%) Example 1 D21-D0 -36.86 Example 2 D21-D0 -30.32 Comparative Example 1 D21-D0 1.22 Comparative Example 2 D21-D0 -30.13 Comparative Example 3 D21-D0 -18.32 Comparative Example 4 D21-D0 -20.34 Comparative Example 5 D21-D0 -23.88 Comparative Example 6 D21-D0 -25.12

[0100] From the results in Table 6, it can be seen that the transepidermal water loss rate of the skin after using the repairing cream provided by Examples 1-2 for 21 days is small; the transepidermal water loss rate of the skin after using the cream provided by Comparative Example 1 and Comparative Examples 3-6 for 21 days is large. TM BC10096, but the transepidermal water loss rate of the skin after its use is not much different from that of the skin after use in Example 2. The repairing cream provided by the present application is compounded with cetyl-PG hydroxyethyl palmitamide, allantoin, sodium acetylated hyaluronate, anti-sensitizer and hydrosol, and the anti-sensitizer includes octyldodecanol, echium plantaginis seed oil, unsaponifiable matter of sunflower seed oil, cymbidium truncatum flower / leaf / vine extract and tocopherol; the hydrosol includes water, glycerin, sodium dihydrogen phosphate, sodium dihydrogen phosphate and soluble collagen, which can effectively improve the skin barrier, reduce transepidermal water loss, and has significant repair effect.

[0101] Test Example 3

[0102] In this test example, the skin feel test of the repairing facial cream provided in Example 1 and Comparative Example 7 was conducted, and the specific method was as follows: (1) Half an hour before the test, wash your hands and the inner side of your forearms with clean water, and wipe them clean with a clean face towel;

[0103] (2) Before use, use a syringe to take 0.2 mL of each repair cream to be tested on a glass slide and observe the color and other indicators;

[0104] (3) When using, first select a 4*4cm area on the inner side of the forearm as the test area, take 0.06mL of each repair cream to be tested and evenly apply it to the test area, use the fingertips to gently massage in circles at a frequency of 2 circles / s for 30s, rinse with clean water, and evaluate and record the various indicators as required. The results are shown in Table 7.

[0105] Table 7 Skin feel of repairing cream

[0106] Test samples Skin feel Example 1 The cream has a firm texture, melts quickly on the hands, and becomes smooth during application. As you continue to apply the cream, it gradually breaks the emulsion and releases the oil phase. Comparative Example 7 The cream melts slower after application, and the smoothness during application decreases

[0107] From the results in Table 7, it can be seen that the repairing facial cream provided by the present application uses a skin softener, a skin softening powder, an emulsifier and a solid oil in combination, and the skin softener is combined with hydrogenated coconut glycerides and jojoba esters; the skin softening powder is combined with lauroyl lysine and cetyl palmitate, has a firm texture, melts quickly on the hands, is smooth during application, and continues to apply the cream to gradually break the emulsion and release the oil phase, has the characteristics of moisturizing, and has a unique multiple skin feel experience.

[0108] The embodiments described above are part of the embodiments of the present application, rather than all of the embodiments. The detailed description of the embodiments of the present application is not intended to limit the scope of the present application for protection, but merely represents the selected embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present application.

Claims

1. A repair composition, characterized in that: The repair composition comprises: allantoin, acetylated sodium hyaluronate, cetyl-PG hydroxyethyl palmitamide, an anti-allergic agent, and a hydrosol; The anti-allergic agent includes octyldodecanol, Echium plantain seed oil, unsaponifiable matter of sunflower seed oil, extract of Cynanchum truncatum flower / leaf / vine and tocopherol; The hydrosol comprises water, glycerol, sodium dihydrogen phosphate, disodium hydrogen phosphate and soluble collagen.

2. The repair composition according to claim 1, characterized in that The repair composition comprises, by weight: 0.05-0.3 parts of allantoin, 0.01-0.1 parts of acetylated sodium hyaluronate, 0.1-2 parts of cetyl-PG hydroxyethyl palmitamide, 0.5-5 parts of anti-allergic agent, and 0.1-5 parts of hydrosol.

3. A repair composition, characterized in that: The repair composition is composed of 0.05-0.3 parts of allantoin, 0.01-0.1 parts of acetylated sodium hyaluronate, 0.1-2 parts of cetyl-PG hydroxyethyl palmitamide, 0.5-5 parts of anti-allergic agent and 0.1-5 parts of hydrosol; The anti-allergic agent is composed of octyldodecanol, Echium plantain seed oil, unsaponifiable matter of sunflower seed oil, extract of Cyperus rotundus flower / leaf / vine and tocopherol; The hydrosol consists of water, glycerol, sodium dihydrogen phosphate, disodium hydrogen phosphate and soluble collagen.

4. Use of the repairing composition according to any one of claims 1 to 3 in preparing cosmetics or medicines with repairing effects.

5. A repairing facial cream, characterized in that: The repairing composition comprises the repairing composition according to any one of claims 1 to 3; the mass percentage of the repairing composition in the repairing cream is 0.76% to 12.4%.

6. The repairing facial cream according to claim 5, characterized in that The repairing facial cream comprises a skin softener, a skin softening powder, an emulsifier and solid oil; Wherein, the skin softener includes hydrogenated coconut glycerides and jojoba esters; The skin softening powder includes lauroyl lysine and cetyl palmitate.

7. The repairing facial cream according to claim 5, characterized in that The emulsifier includes cetearyl alcohol, steareth-21 and glyceryl stearate; And / or, the solid fat comprises white beeswax.

8. The repairing facial cream according to claim 6 or 7, characterized in that: The repairing facial cream also includes auxiliary materials, and the auxiliary materials include at least one of moisturizers, thickeners, emollients, softeners, antioxidants, protective agents, preservatives, fragrances, and colorants.

9. A repairing facial cream, characterized in that: The repairing facial cream comprises, by mass percentage: 0.05%-0.3% allantoin, 0.01%-0.1% acetylated sodium hyaluronate, 0.1%-2% cetyl-PG hydroxyethyl palmitamide, 0.5%-5% anti-allergic agent, 0.1%-5% hydrosol, 1%-2.5% hydrogenated coconut glycerides, 1%-2.5% jojoba esters, 0.5%-3% lauroyl lysine, 0.5%-1.5% cetyl palmitate, 1.75%-3.25% cetearyl alcohol, 0.8%-1.5% steareth-21, 1.5%-2.5% glyceryl stearate, 0.5%-2% white beeswax; the rest is water; The anti-allergic agent includes octyldodecanol, Echium plantain seed oil, unsaponifiable matter of sunflower seed oil, extract of Cyperus rotundus flower / leaf / vine and tocopherol; and the hydrosol includes water, glycerin, sodium dihydrogen phosphate, sodium dihydrogen phosphate and soluble collagen.

10. The repairing facial cream according to claim 9, characterized in that The repairing facial cream further comprises auxiliary materials in an amount of 20.4% to 59.9% by mass.

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