Traditional Chinese medicine composition for adjuvant therapy of cancer and preparation method thereof

Abstract

The invention relates to the technical field of traditional Chinese medicine. The invention provides a traditional Chinese medicine composition for adjuvant therapy of cancers and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises 8-15 parts of wild ganoderma lucidum and 10-20 parts of duchesnea indica. The invention further provides a medicine containing the traditional Chinese medicine composition. The dosage form of the medicine comprises decoction, granules, pills, capsules and the like. According to the technical scheme, through the compatibility of the wild ganoderma lucidum and the duchesnea indica, the effects of better assisting in inhibiting tumor cell growth and inducing cell apoptosis are achieved, meanwhile, the immunity of the human body can be remarkably enhanced for double-effect adjustment, and finally the effect of assisting in treating cancer is achieved. In addition, by using the technical scheme, the extraction of effective components in the components is ensured to the greatest extent.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicines, and in particular to a traditional Chinese medicine composition for adjuvant treatment of cancer and a preparation method thereof. Background Art

[0002] Cancer is a malignant disease that seriously threatens human life and health, and the mortality rate of cancer is very high. For a long time, the main means of treating cancer include surgery, radiotherapy and chemotherapy. The anti-tumor drugs on the market are mainly chemical drugs, but traditional chemical drugs have limited efficacy and also have large toxic side effects. Patients often cannot persist in taking the drugs. In addition, long-term use of drugs will also suppress the patient's immune function, which is not conducive to the treatment of tumors, and even induce various drug-induced diseases that seriously affect the patient's quality of life.

[0003] Based on the above, it is very necessary to study a drug with good auxiliary effect in cancer treatment and few side effects. Summary of the invention

[0004] The purpose of the present invention is to provide a Chinese medicine composition for assisting the treatment of cancer. The combination of wild ganoderma and snakeberry can achieve better auxiliary inhibition of tumor cell growth and induction of cell apoptosis, and can also significantly enhance human immunity for dual-effect regulation, ultimately achieving the effect of assisting the treatment of cancer with little side effects.

[0005] In order to achieve the above-mentioned object of the invention, the present invention provides the following technical solutions:

[0006] The invention provides a traditional Chinese medicine composition for assisting cancer treatment, comprising the following components in parts by weight: 8-15 parts of wild ganoderma lucidum and 10-20 parts of snakeberry.

[0007] The present invention also provides a preparation method of the traditional Chinese medicine composition, comprising the following steps: adding water to wild ganoderma and duchesnea indica respectively, soaking them, then decocting and filtering to obtain wild ganoderma extract and duchesnea indica extract; mixing the wild ganoderma extract and duchesnea indica extract to obtain the traditional Chinese medicine composition.

[0008] Preferably, the amount of water added to the wild Ganoderma lucidum is 4-7 times the mass of the wild Ganoderma lucidum, and the amount of water added to the Duchesnea indica is 3-5 times the mass of the Duchesnea indica.

[0009] Preferably, the soaking time of the wild ganoderma is 20-40 min; the soaking time of the snakeberry is 20-30 min.

[0010] Preferably, the decocting method is to first boil over high heat and then continue decocting over low heat.

[0011] Preferably, the decoction time of the wild ganoderma and the snakeberry is independently 30-50 min / time, and the decoction times are independently 2-3 times.

[0012] The present invention also provides a medicine for adjuvant treatment of cancer, comprising the traditional Chinese medicine composition.

[0013] Preferably, the dosage form of the drug includes decoction, granules, pills and capsules.

[0014] By adopting the above technical solution, the present invention has the following beneficial effects:

[0015] The combination of wild ganoderma and snakeberry in the technical solution of the present invention can better assist in inhibiting tumor cell growth and inducing cell apoptosis, and can also significantly enhance human immunity for dual-effect regulation, ultimately achieving the effect of assisting cancer treatment. The use of the composition has little side effects on the human body and also reduces the generation of secondary risks. In addition, the preparation method of the present invention also guarantees the extraction of effective ingredients in the components to the greatest extent. DETAILED DESCRIPTION

[0016] The invention provides a traditional Chinese medicine composition for auxiliary treatment of cancer, comprising wild ganoderma lucidum and duchesnea indica.

[0017] In the present invention, the wild ganoderma is rich in fatty acids, inorganic elements, alkaloids, sterols and other nutritional ingredients, which can inhibit tumor growth and have anti-cancer effects. It can also significantly improve the body's immune function and enhance the patient's own anti-cancer ability.

[0018] In the present invention, the main components of the snakeberry include saponins, flavonoids and a variety of active substances, which have significant anti-inflammatory and antioxidant effects; one of the main components, eugenol, can inhibit tumor cell growth and induce tumor cell apoptosis, which can achieve the effect of assisting in inhibiting tumor growth to a certain extent. In addition, the snakeberry can also enhance the human immune function.

[0019] In the present invention, the weight proportion of the wild ganoderma is preferably 8-15 parts, further preferably 9-13 parts, further preferably 12 parts; the weight proportion of the snakeberry is preferably 10-20 parts, further preferably 12-18 parts, further preferably 16 parts.

[0020] The present invention also provides a preparation method of the traditional Chinese medicine composition, comprising the following steps: adding water to wild ganoderma and duchesnea indica respectively, soaking them, then decocting and filtering to obtain wild ganoderma extract and duchesnea indica extract; mixing the wild ganoderma extract and duchesnea indica extract to obtain the traditional Chinese medicine composition.

[0021] In the present invention, the wild ganoderma is chopped into small pieces, and then water is added to the chopped wild ganoderma and snakeberry respectively. The amount of water added to the wild ganoderma is preferably 4-7 times the mass of the wild ganoderma, further preferably 5-6.5 times, and further preferably 6 times; the amount of water added to the snakeberry is preferably 3-5 times the mass of the snakeberry, further preferably 3.5-4.5 times, and further preferably 4 times.

[0022] In the present invention, after adding water and soaking, the soaking time of the wild ganoderma is preferably 20-40 minutes, more preferably 25-35 minutes, and more preferably 30 minutes; the soaking time of the snakeberry is preferably 20-30 minutes, more preferably 22-28 minutes, and more preferably 25 minutes.

[0023] In the present invention, decocting is performed after the soaking is completed, and the decocting method is preferably to first boil with high heat and then continue to decoct with low heat. The decoction time of the wild ganoderma lucidum of the present invention is preferably 30-50min / time, further preferably 35-45min, and further preferably 40min; the number of times the wild ganoderma lucidum is decocted is preferably 2-3 times, and further preferably 3 times. The decoction time of the snakeberry of the present invention is preferably 30-50min / time, further preferably 35-48min, and further preferably 45min; the number of times the snakeberry is decocted is preferably 2-3 times, and further preferably 3 times. After each decoction, it is preferably filtered, the filtrate is collected, and the obtained filtrate is combined to obtain a wild ganoderma lucidum extract and a snakeberry extract. The decoction process of the present invention can effectively avoid destroying the active ingredients of wild ganoderma lucidum and snakeberry, and can extract the effective ingredients in the two components to the greatest extent.

[0024] In the present invention, the wild ganoderma lucidum extract and the snakeberry extract are mixed to obtain the traditional Chinese medicine composition.

[0025] The present invention also provides a medicine for adjuvant treatment of cancer, comprising the Chinese medicine composition.

[0026] In the present invention, the dosage form of the drug includes decoction, granules, pills and capsules.

[0027] The technical solutions provided by the present invention are described in detail below in conjunction with the embodiments, but they should not be construed as limiting the protection scope of the present invention.

[0028] Example 1

[0029] A traditional Chinese medicine composition for assisting cancer treatment consists of 12 parts of wild ganoderma and 16 parts of snakeberry.

[0030] The preparation method of the above-mentioned Chinese medicine composition comprises the following steps:

[0031] (1) Mixing wild ganoderma with water and soaking the mixture, wherein the amount of water added is 6 times the mass of the wild ganoderma, and the mixture is soaked for 30 minutes. Then, the mixture is boiled over high heat and then decocted over low heat for 40 minutes each time, and the mixture is decocted for 3 times. After each decoction, the mixture is filtered, the filtrate is collected, and the filtrate is combined to obtain a wild ganoderma extract;

[0032] (2) mixing the snakeberry with water and soaking the mixture, adding water in an amount of 4 times the mass of the snakeberry, soaking for 25 minutes, then boiling over high heat, and then continuing to decoct over low heat, decoct for 45 minutes each time, decoct for 3 times, filter after each decoction, collect the filtrate, and combine the filtrates to obtain a snakeberry extract;

[0033] (3) The wild ganoderma extract and the snakeberry extract are mixed to obtain the traditional Chinese medicine composition.

[0034] Example 2

[0035] A traditional Chinese medicine composition for assisting cancer treatment consists of 15 parts of wild ganoderma and 20 parts of snakeberry.

[0036] The preparation method of the above-mentioned Chinese medicine composition comprises the following steps:

[0037] (1) Mixing wild ganoderma with water and soaking the mixture, wherein the amount of water added is 7 times the mass of the wild ganoderma, and the mixture is soaked for 40 minutes. Then, the mixture is boiled over high heat and then decocted over low heat for 30 minutes each time, and the mixture is decocted for 3 times. After each decoction, the mixture is filtered, the filtrate is collected, and the filtrate is combined to obtain a wild ganoderma extract;

[0038] (2) mixing the snakeberry with water and soaking the mixture, adding 5 times the mass of the snakeberry, soaking for 30 minutes, then boiling over high heat, and then continuing to decoct over low heat, decoct for 50 minutes each time, decoct for 3 times, filter after each decoction, collect the filtrate, and combine the filtrates to obtain a snakeberry extract;

[0039] (3) The wild ganoderma extract and the snakeberry extract are mixed to obtain the traditional Chinese medicine composition.

[0040] Example 3

[0041] A traditional Chinese medicine composition for assisting cancer treatment consists of 8 parts of wild ganoderma and 10 parts of snakeberry.

[0042] The preparation method of the above-mentioned Chinese medicine composition comprises the following steps:

[0043] (1) Mixing wild ganoderma with water and soaking the mixture, wherein the amount of water added is 4 times the mass of the wild ganoderma, and the mixture is soaked for 20 minutes. Then, the mixture is boiled over high heat and then decocted over low heat for 50 minutes each time, and the mixture is decocted for 3 times. After each decoction, the mixture is filtered, the filtrate is collected, and the filtrate is combined to obtain a wild ganoderma extract;

[0044] (2) mixing the snakeberry with water and soaking the mixture, adding 3 times the mass of the snakeberry, soaking for 20 minutes, then boiling over high heat, and then decocting over low heat for 30 minutes each time, decocting for 3 times, filtering after each decoction, collecting the filtrate, and combining the filtrates to obtain a snakeberry extract;

[0045] (3) The wild ganoderma extract and the snakeberry extract are mixed to obtain the traditional Chinese medicine composition.

[0046] Test Example 1

[0047] Zhang, male, 43 years old, from Zigong, Sichuan. The patient was diagnosed with malignant rectal cancer in 2022. After surgical treatment in the hospital, he suffered from malignant vomiting during chemotherapy and stopped chemotherapy after he became unbearable. A friend learned about the Chinese medicine treatment method of the inventor's clinic and went to the clinic for consultation. After taking the Chinese medicine composition of the present invention for two months, one dose a day, the malignant vomiting disappeared; after continuing to take the Chinese medicine composition of the present invention for comprehensive maintenance for 9 months, the condition was stable and there was no recurrence.

[0048] Test Example 2

[0049] Xu, female, 55 years old, from Chongqing. She was hospitalized for dysphagia, choking and foreign body sensation behind the sternum, and was eventually diagnosed with early esophageal cancer. The patient's family was in financial difficulty, and because of the high cost of surgery and radiotherapy, she gave up treatment. Later, she heard about the Chinese medicine treatment method of the inventor's clinic, so she came for a consultation. After taking the Chinese medicine composition of the present invention once a day for three months, the dysphagia, choking and foreign body sensation behind the sternum were significantly reduced; after taking it for six months, she went to the hospital for another examination, and the tumor cells not only did not expand and spread, but also decreased significantly.

[0050] Test Example 3

[0051] Zhao, male, 52 years old, from Nanchuan District, Chongqing. In the early stage, he had symptoms of fullness, discomfort and nausea, but thought it was a common gastrointestinal disease and did not take it seriously; after a period of time, he went to the hospital for treatment due to upper abdominal pain, vomiting blood, and even black stools, and was diagnosed with mid-to-late stage gastric cancer. The patient did not undergo surgery or chemotherapy due to personal physical reasons and cost reasons. In order to seek conservative treatment of traditional Chinese medicine, he came to the inventor's clinic for treatment. After taking the Chinese medicine composition of the present invention for three months, one dose a day, the upper abdominal pain was relieved, and the black stools and vomiting blood were also improved to a certain extent; after continuing to take it for one year, he went to the hospital for examination again. Compared with the previous examination results, the tumor cells did not spread, and even the range of tumor cells was reduced.

[0052] In summary, it can be seen that the combination of wild ganoderma and snakeberry in the technical solution of the present invention can better assist in inhibiting tumor cell growth and inducing cell apoptosis, and ultimately achieve the effect of assisting in the treatment of cancer; at the same time, it can also significantly enhance human immunity. The use of the combination has little side effects on the human body and also reduces the generation of secondary risks.

[0053] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A Chinese medicine composition for adjuvant treatment of cancer, characterized in that: The invention comprises the following components in parts by weight: 8-15 parts of wild ganoderma lucidum and 10-20 parts of snakeberry.

2. The method for preparing the Chinese medicine composition according to claim 1, characterized in that: The steps include: Water is added to the wild ganoderma and the indica respectively, and the mixture is soaked, then boiled and filtered to obtain the wild ganoderma extract and the indica extract; the wild ganoderma extract and the indica extract are mixed to obtain the traditional Chinese medicine composition.

3. The preparation method according to claim 2, characterized in that: The amount of water added to the wild ganoderma is 4-7 times the mass of the wild ganoderma, and the amount of water added to the snakeberry is 3-5 times the mass of the snakeberry.

4. The preparation method according to claim 2, characterized in that: The soaking time of the wild ganoderma lucidum is 20-40 minutes; the soaking time of the snakeberry is 20-30 minutes.

5. The preparation method according to claim 2, characterized in that: The decocting method is to first boil over high heat and then continue decocting over low heat; The decoction time of the wild ganoderma and the snakeberry is independently 30-50 minutes per time, and the decoction times are independently 2-3 times.

6. A drug for adjuvant treatment of cancer, characterized in that: A Chinese medicine composition comprising the Chinese medicine composition of claim 1 or a Chinese medicine composition prepared by the preparation method of any one of claims 2-5.

7. The drug according to claim 6, characterized in that The dosage forms of the medicine include decoction, granules, pills and capsules.