Circulating suction device and system

Abstract

The present invention provides a cyclic aspiration device and system, which relates to the technical field of medical devices and includes: a perfusion mechanism, a first pressure sensor, and an on-off control mechanism; the on-off control mechanism is respectively connected to the perfusion mechanism, an aspiration catheter, and a thrombus collection device through pipelines, and the first pressure sensor is arranged between the on-off control mechanism and the aspiration catheter; wherein, the on-off control mechanism is used to control the on-off state of the pipeline; the perfusion mechanism is used to provide perfusion liquid for the pipeline between the aspiration catheter and the on-off control mechanism; the first pressure sensor is used to measure the pressure value of the pipeline between the aspiration catheter and the on-off control mechanism. The present invention has the capabilities of thrombus fragmentation, thrombus movement control, and blockage clearance of the aspiration catheter.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a circulating aspiration device and system. Background Art

[0002] Deep vein thrombosis refers to the formation of blood clots in the venous blood vessels, which can occur in any deep vein. Generally, deep vein thrombosis occurs in the lower extremities or pelvis, but it can also occur in the upper extremities, abdominal veins or brain, etc. Currently, the treatment methods for deep vein thrombosis usually include anticoagulant therapy, catheter-directed thrombolysis (CDT) and mechanical thrombectomy.

[0003] For mechanical thrombectomy, the existing mechanical thrombectomy devices have the following problems: they do not have the ability to break thrombus, insufficient ability to aspirate subacute thrombus; they do not have the ability to control the movement of thrombus in the catheter; they cannot solve the problem of catheter blockage and dredging, etc. Summary of the Invention

[0004] In view of this, the purpose of the present invention is to provide a circulating aspiration device and system, which have the ability to break thrombus, the ability to control thrombus movement and the ability to dredge the blocked aspiration catheter.

[0005] In the first aspect, an embodiment of the present invention provides a circulating aspiration device, including: a perfusion mechanism, a first pressure sensor and a on-off control mechanism;

[0006] The on-off control mechanism is connected to the perfusion mechanism, the aspiration catheter and the thrombus collection device through pipelines respectively, and the first pressure sensor is arranged between the on-off control mechanism and the aspiration catheter;

[0007] Wherein, the on-off control mechanism is used to control the on-off state of the pipeline; the perfusion mechanism is used to provide perfusion liquid for the pipeline between the aspiration catheter and the on-off control mechanism; the first pressure sensor is used to measure the pressure value of the pipeline between the aspiration catheter and the on-off control mechanism.

[0008] In one embodiment, the pipeline includes a main pipeline and a branch pipeline, and the on-off control mechanism includes an aspiration on-off control mechanism and a perfusion on-off control mechanism;

[0009] The aspiration on-off control mechanism is arranged on the main pipeline, and the aspiration on-off control mechanism is used to control the on-off state of the main pipeline between the aspiration catheter and the thrombus collection device; the first pressure sensor is arranged between the aspiration on-off control mechanism and the aspiration catheter;

[0010] The perfusion on-off control mechanism is arranged on the branch pipeline to connect the perfusion mechanism to the main pipeline between the aspiration catheter and the aspiration on-off control mechanism through the branch pipeline, and the perfusion on-off control mechanism is used to control the on-off state between the perfusion mechanism and the main pipeline.

[0011] In one embodiment, the working mode of the cyclic suction device includes a thrombus fragmentation mode, and the perfusion on-off control mechanism and the suction on-off control mechanism in the thrombus fragmentation mode are in an interlocking relationship;

[0012] The perfusion on-off control mechanism controls the branch side pipeline to be disconnected, and the suction on-off control mechanism controls the main pipeline to be connected; or, the perfusion on-off control mechanism controls the branch side pipeline to be connected, and the suction on-off control mechanism controls the main pipeline to be disconnected.

[0013] In one embodiment, the working mode of the cyclic suction device includes a thrombus movement control mode, and the perfusion on-off control mechanism and the suction on-off control mechanism in the thrombus movement control mode are in a linkage relationship;

[0014] The perfusion on-off control mechanism controls the conduction of the branch side pipeline, and the suction on-off control mechanism controls the conduction of the main pipeline;

[0015] The time during which the branch pipeline is turned on by the perfusion on-off control mechanism is shorter than the time during which the main pipeline is turned on by the suction on-off control mechanism.

[0016] In one embodiment, the perfusion mechanism operates continuously, the perfusion on-off control mechanism controls the branch line to be continuously connected, and the suction on-off control mechanism controls the main line to be indirectly connected;

[0017] The amount of perfusion liquid provided by the perfusion mechanism during the period when the perfusion on-off control mechanism controls the conduction of the branch pipeline is less than the amount of suction by the thrombus collection device during the period when the suction on-off control mechanism controls the conduction of the main pipeline.

[0018] In one embodiment, the perfusion mechanism is continuously operated, and a pressurized state is maintained between the perfusion mechanism and the perfusion on-off control mechanism;

[0019] The perfusion volume of the perfusion mechanism is related to the time during which the perfusion on-off control mechanism controls the conduction of the branch line. The perfusion liquid volume of the perfusion mechanism is less than the single aspiration volume of the thrombus collection device.

[0020] In one embodiment, the circulating suction device further includes a second pressure sensor, which is disposed on the branch-side pipeline and is used to measure the pressure value on the branch-side pipeline.

[0021] In one embodiment, the thrombus collection device includes a thrombus collection tank body and a vacuum pump, and the thrombus collection tank body and the vacuum pump are connected via a main pipeline;

[0022] The circulating suction device also includes a third pressure sensor, which is arranged on the main pipeline and is used to measure the pressure value of the main pipeline between the thrombus collection tank and the vacuum pump.

[0023] In one embodiment, the cyclic aspiration device further includes a processor, which is electrically connected to the first pressure sensor, the second pressure sensor, and the third pressure sensor;

[0024] The processor is configured to identify whether a thrombus is aspirated by the aspiration catheter based on one or more of the pressure values respectively collected by the first pressure sensor, the second pressure sensor, and the third pressure sensor, and / or to identify the pipe diameter value of the main pipeline, and the pipe diameter value is negatively correlated with the on-off frequency corresponding to the aspiration on-off control mechanism.

[0025] In one embodiment, the on-off control mechanism is an overall on-off control structure, and the overall on-off control structure uses a two-way three-way valve, which is used to control the on-off state of the pipeline between the aspiration catheter and the thrombus collection device, and is also used to control the on-off state of the pipeline between the perfusion mechanism and the aspiration catheter.

[0026] In one embodiment, the cyclic aspiration device further includes a housing, which is used to provide protection for the perfusion mechanism, the first pressure sensor, and the on-off control mechanism; or, it is used to provide protection for the perfusion mechanism, the first pressure sensor, the on-off control mechanism, and the thrombus collection device.

[0027] In a second aspect, an embodiment of the present invention further provides a cyclic aspiration system, including the cyclic aspiration device according to any one of the first aspect.

[0028] The cyclic aspiration device and system provided by the embodiments of the present invention include: a perfusion mechanism, a first pressure sensor, and an on-off control mechanism. The on-off control mechanism is connected to the perfusion mechanism, the aspiration catheter, and the thrombus collection device through pipelines respectively, and the first pressure sensor is arranged between the on-off control mechanism and the aspiration catheter; wherein, the on-off control mechanism is used to control the on-off state of the pipeline; the perfusion mechanism is used to provide perfusion liquid for the pipeline between the aspiration catheter and the on-off control mechanism; the first pressure sensor is used to measure the pressure value of the pipeline between the aspiration catheter and the on-off control mechanism. The above device can identify the pipeline diameter and whether a thrombus is aspirated by the aspiration catheter based on the pressure value. In the case of aspirating a thrombus, the perfusion mechanism can provide perfusion liquid for the pipeline, and combined with the on-off control mechanism to change the on-off state of the pipeline, the perfusion liquid can drive the thrombus in the pipeline to move, so as to achieve the thrombus fragmentation function and the thrombus movement control function. In addition, when the aspiration catheter is blocked due to aspirating a thrombus, the perfusion liquid can be used to dredge the aspiration catheter.

[0029] Other features and advantages of the present invention will be described in the following specification, and, in part, will be obvious from the specification, or will be understood by implementing the present invention. The objectives and other advantages of the present invention are achieved and obtained by the structures specifically pointed out in the specification, the claims, and the drawings.

[0030] To make the above objects, features, and advantages of the present invention more apparent and understandable, the following provides preferred embodiments in conjunction with the accompanying drawings and describes them in detail as follows. Description of the Drawings

[0031] To more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following will briefly introduce the drawings required for the description of the specific embodiments or the prior art. Obviously, the drawings in the following description are some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings.

[0032] Figure 1 Structural schematic diagram of a cyclic aspiration device provided by an embodiment of the present invention;

[0033] Figure 2 Specific structural schematic diagram of a cyclic aspiration device provided by an embodiment of the present invention;

[0034] Figure 3 Connection schematic diagram of a cyclic aspiration device provided by an embodiment of the present invention;

[0035] Figure 4 Schematic diagram of a shutter structure provided by an embodiment of the present invention;

[0036] Figure 5 Partial structural schematic diagram of a cyclic aspiration device in a thrombus fragmentation mode provided by an embodiment of the present invention;

[0037] Figure 6 Partial structural schematic diagram of a cyclic aspiration device in a thrombus movement control mode provided by an embodiment of the present invention;

[0038] Figure 7 Partial structural schematic diagram of another cyclic aspiration device in a thrombus movement control mode provided by an embodiment of the present invention;

[0039] Figure 8 Partial structural schematic diagram of a cyclic aspiration device in a dredging aspiration catheter mode provided by an embodiment of the present invention;

[0040] Figure 9 Partial structural schematic diagram of another cyclic aspiration device in a dredging aspiration catheter mode provided by an embodiment of the present invention;

[0041] Figure 10 Specific structural schematic diagram of a cyclic aspiration device provided by an embodiment of the present invention.

[0042] Icons: 1 - First pressure sensor; 2 - Second pressure sensor; 3 - Third pressure sensor; 4 - Suction on-off control mechanism; 5 - Perfusion on-off control mechanism; 6 - Perfusion mechanism; 7 - Main pipeline; 8 - Branch side pipeline; 9 - First pipe orifice; 10 - Second pipe orifice; 11 - Third pipe orifice; 12 - Overall on-off control structure. Detailed implementation manners

[0043] To make the objectives, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions of the present invention will be clearly and completely described below in conjunction with the embodiments. Apparently, the described embodiments are some but not all of the embodiments of the present invention. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0044] Deep vein thrombosis refers to the formation of blood clots in the venous blood vessels, which can occur in any deep vein. Generally, deep vein thrombosis occurs in the lower extremities or pelvis, but it can also occur in the upper extremities, abdominal veins or brain, etc. Deep vein thrombosis is a common clinical complication in trauma and emergency patients, and its annual incidence is about 1 / 1000 people. Due to the particularity of deep vein thrombosis: 1) Deep vein thrombosis often has no special clinical symptoms, and its diagnosis can often only be carried out through some routine screenings, which requires a large amount of manpower and medical resources. 2) The detachment of lower limb thrombus can cause pulmonary embolism (PE), resulting in unstable hemodynamics and endangering life. 3) Veins contain venous valves, and treatments applicable to arteries such as rotational ablation will damage the function of venous valves, resulting in the loss of venous blood transfusion function. Currently, the common treatment methods for deep vein thrombosis usually include anticoagulant therapy, catheter-directed thrombolysis (CDT) and mechanical thrombus aspiration therapy.

[0045] Anticoagulant therapy: The role of anticoagulant therapy is to prevent the thrombus from spreading further or forming new thrombi, and to strive for conditions for the opening of collateral circulation to relieve symptoms. The most serious complications during anticoagulant therapy are bleeding and the detachment of old thrombi. Once bleeding and thrombus detachment occur, it will cause serious harm to the patient.

[0046] Catheter-directed thrombolysis (CDT): Catheter-directed thrombolysis (CDT) has currently become a commonly used treatment method for acute DVT. Compared with traditional systemic anticoagulant therapy, it can accelerate thrombus dissolution while effectively reducing bleeding complications. The degree of improvement in the quality of life of patients by thrombolytic therapy is positively correlated with the degree of thrombus dissolution. Although CDT is an effective treatment measure that can relieve the pain of patients, CDT increases the bleeding complications of patients. Especially for patients with a recent history of major surgery, the clinical application of CDT is relatively limited, and the thrombolytic effect on old thrombi is not good, which severely limits the effect of CDT.

[0047] Mechanical thrombectomy: Mechanical thrombectomy can quickly remove thrombi, improve clinical symptoms, reduce the use of urokinase at the same time, and increase the safety of treatment. Improving the efficiency of thrombus removal, shortening the treatment cycle, expanding the scope of treatment indications while reducing the bleeding risk is the current direction of clinical research. A typical product is the AngioJet (Boston Scientific) mechanical thrombus removal system. This system is a new minimally invasive treatment technology widely carried out in domestic clinics in recent years. It is a thrombus removal system that combines drug and mechanical effects (percutaneous mechanical thrombectomy PMT). It mainly uses the principle of hydrodynamic force to break up and aspirate thrombi, so as to quickly remove thrombi and relieve venous obstruction. Literature reports "believe that the AngioJet mechanical thrombus removal system is safe and effective. When used in combination with CDT, it can reduce the dose of thrombolytic drugs and shorten the hospital stay. This product has the following problems: 1) During the thrombus aspiration process, red blood cells are broken up by the high-speed jet of liquid, resulting in hemoglobinuria, renal function damage, and even renal failure; 2) During the thrombus aspiration process, the injection speed of the normal saline used for flushing cannot be controlled, and the purpose of accurately and powerfully flushing the thrombus cannot be achieved; 3) The structure is complex, there are many disposable consumables, and the manufacturing cost is high, resulting in a high selling price.

[0048] At present, traditional mechanical thrombus aspiration devices have the following defects: Viscous thrombi (thrombi with a certain toughness) will block the aspiration catheter and cannot continue to aspirate; The structure is complex, there are many disposable consumables, and the manufacturing cost is high, resulting in a high selling price; The control mode is single and the automatic and manual functions cannot be freely switched; It can only deal with a single type of thrombus, can only aspirate acute thrombi intelligently, and has no aspiration ability for subacute thrombi (thrombi with a certain toughness); It does not have the function of breaking up thrombi and aspirates after breaking up the thrombi; The flow rate of thrombi in the catheter drops suddenly with the entry of thrombi into the catheter, and the aspiration effect becomes poor; After the aspiration catheter aspirates a large amount of thrombi, it is completely blocked and does not have the ability to dredge and clean the thrombi in the catheter.

[0049] To address some technical issues, related technologies have provided a device and method for controlled clot aspiration (Patent Application Publication No. CN 112533550 A). A vacuum aspiration control system for use with a vacuum source and an aspiration catheter includes a connecting tube configured to connect the vacuum source to the lumen of the aspiration catheter. An on-off valve is operably coupled to the connecting tube, and a sensing unit is configured to detect the flow within the connecting tube and provide a signal representative of the flow. A controller receives the signal to determine whether to open or close the valve. The controller can automatically close the valve to shut off the flow when the flow through the connecting tube is unconstrained or according to a predetermined timing sequence. The controller can also periodically open the closed valve to determine whether the flow has entered an acceptable range. The controller can also perform pulsed aspiration using a pressure manipulation assembly when the flow is restricted or blocked. An intermittent thrombus aspiration pump system and method of use are also provided (Patent Application Publication No. CN 112316232 A), including an aspiration device and a control device. The control device includes a pressure sensor, a gas path control valve, a control circuit board, an aspiration connector, and a catheter connector. One end of the catheter connector is connected to the aspiration catheter, and the other end of the catheter connector is sequentially connected to the gas path control valve and the aspiration connector. The pressure sensor is connected to the air passage between the catheter connector and the gas path control valve. The pressure sensor and the gas path control valve are electrically connected to the control circuit board respectively. Through the cooperation between the control device and the aspiration device, the aspiration action only starts when the aspiration negative pressure reaches a certain value, realizing intermittent aspiration, improving the suction force of the aspiration pump system, reducing the aspiration time, thereby reducing the patient's blood loss and facilitating the patient's subsequent recovery.

[0050] However, through research, the applicant has found that the existing technologies still have the following problems: they do not have the ability to break thrombus, have insufficient ability to aspirate subacute thrombus; they do not have the ability to control the movement of thrombus within the catheter; for the thrombus aspiration devices with cycle control on the market, due to structural limitations, all aspiration modes need to be operated under the control of the control device, and there is no manually operated aspiration mode, resulting in a single control mode, which makes the operator lack an important option under special conditions; they cannot solve the problem of catheter blockage and dredging; they cannot intelligently distinguish the diameter and length of the catheter.

[0051] Based on this, the embodiments of the present invention provide a cyclic aspiration device and system to address the above problems. The embodiments of the present invention at least possess the abilities of thrombus fragmentation, thrombus movement control, and aspiration catheter blockage dredging.

[0052] To facilitate the understanding of this embodiment, first, a cyclic aspiration device disclosed in the embodiments of the present invention will be introduced in detail. Refer to Figure 1 the structural schematic diagram of a cyclic aspiration device as shown, which includes: a perfusion mechanism, a first pressure sensor, and a on-off control mechanism.

[0053] In one embodiment, the on-off control mechanism is connected to the perfusion mechanism, the aspiration catheter, and the thrombus collection device via pipelines respectively, and the first pressure sensor is arranged between the on-off control mechanism and the aspiration catheter. The perfusion mechanism can be a perfusion pump.

[0054] In one example, the pipeline is divided into a main pipeline and a branch pipeline. The on-off control mechanism includes an aspiration on-off control mechanism. The first pressure sensor and the aspiration on-off control mechanism are connected through the main pipeline. One end of the main pipeline is connected to the aspiration catheter, and the other end is connected to the thrombus collection device; the perfusion mechanism is connected through the branch pipeline. One end of the branch pipeline is connected to the perfusion liquid storage device, and the other end is connected to the main pipeline between the aspiration catheter and the aspiration on-off control mechanism. The perfusion position is on the side of the on-off control mechanism close to the thrombus.

[0055] In another example, the pipeline is divided into a main pipeline and a branch pipeline. The on-off control mechanism includes an aspiration on-off control mechanism and a perfusion on-off control mechanism. The first pressure sensor and the aspiration on-off control mechanism are connected through the main pipeline. One end of the main pipeline is connected to the aspiration catheter, and the other end is connected to the thrombus collection device; the perfusion mechanism and the perfusion on-off mechanism are connected through the branch pipeline. One end of the branch pipeline close to the perfusion mechanism is connected to the perfusion liquid storage device, and the end close to the perfusion on-off mechanism is connected to the main pipeline between the aspiration catheter and the aspiration on-off control mechanism. The perfusion position is on the side of the on-off control mechanism close to the thrombus.

[0056] In another example, the pipeline is divided into a main pipeline and a branch pipeline. The on-off control mechanism is an overall on-off control mechanism. The first pressure sensor and the overall on-off control mechanism are connected through the main pipeline. One end of the main pipeline is connected to the aspiration catheter, and the other end is connected to the thrombus collection device; the perfusion mechanism is connected through the branch pipeline. One end of the branch pipeline is connected to the perfusion liquid storage device, and the other end is connected to the overall on-off control mechanism.

[0057] Among them, the on-off control mechanism is used to control the on-off state of the pipeline. Specifically, for the aforementioned aspiration on-off control mechanism, it is used to control the on-off state of the main pipeline between the aspiration catheter and the thrombus collection device; for the aforementioned perfusion on-off control mechanism, it is used to control the on-off state of the branch pipeline between the perfusion mechanism and the main pipeline; for the aforementioned overall on-off control mechanism, it is used to control the on-off state of the main pipeline between the aspiration catheter and the thrombus collection device, and to control the on-off state of the branch pipeline between the perfusion mechanism and the main pipeline.

[0058] Among them, the perfusion mechanism is used to provide perfusion liquid for the pipeline between the aspiration catheter and the on-off control mechanism. By controlling the on-off state of the pipeline through the on-off control mechanism, the perfusion mechanism can drive the thrombus in the main pipeline, thereby realizing functions such as thrombus fragmentation, thrombus movement control, and aspiration catheter dredging.

[0059] Among them, the first pressure sensor is used to measure the pressure value of the pipeline between the aspiration catheter and the on-off control mechanism. This pressure value can be used to identify the pipe diameter value of the main pipeline and can also be used to identify whether the aspiration catheter aspirates a thrombus.

[0060] The circulating aspiration device provided by the embodiment of the present invention can identify the pipe diameter of the pipeline and whether the aspiration catheter aspirates a thrombus by using the pressure value. In the case of aspirating a thrombus, the perfusion mechanism can provide perfusion liquid for the pipeline, and combined with the on-off control mechanism to change the on-off state of the pipeline, the perfusion liquid can drive the thrombus in the pipeline to move, so as to achieve the thrombus fragmentation function and the thrombus movement control function. In addition, when the aspiration catheter is blocked due to aspirating a thrombus, the perfusion liquid can be used to dredge the aspiration catheter.

[0061] The purpose of the embodiment of the present invention is to provide a thrombus extraction instrument with circulating aspiration (abbreviated as circulating aspiration device). This circulating aspiration device integrates the circulating control system and the aspiration system, and has the characteristics of small volume, easy to carry, and low cost. The circulating aspiration device is composed of an aspiration on-off control mechanism, a perfusion on-off control mechanism, and a pressure sensor, and is used in cooperation with a vacuum pump and is connected to the thrombus collection tank of the vacuum pump.

[0062] In one embodiment, the embodiment of the present invention provides a specific structural schematic diagram of a circulating aspiration device as shown in Figure 2 which includes a first pressure sensor 1, a second pressure sensor 2, a third pressure sensor 3, an aspiration on-off control mechanism 4, a perfusion on-off control mechanism 5, a perfusion mechanism 6, a main pipeline 7, a branch pipeline 8, a first pipe orifice 9, a second pipe orifice 10, and a third pipe orifice 11.

[0063] Among them, the pipeline includes a main pipeline 7 and a branch pipeline 8, and the on-off control mechanism includes an aspiration on-off control mechanism 4 and a perfusion on-off control mechanism 5.

[0064] For easy understanding, refer to the connection schematic diagram of a circulating aspiration device as shown in Figure 3 which.

[0065] In one example, Figure 2 、 Figure 3 schematically shows that the aspiration on-off control mechanism 4 is arranged on the main pipeline 7.

[0066] Furthermore, the first pipe orifice 9 on the main pipeline 7 is connected to a thrombus collection device. The thrombus collection device includes a thrombus collection tank and a vacuum pump. The thrombus collection tank and the vacuum pump are connected through the main pipeline. The vacuum pump is also a negative pressure pump. Specifically, the first pipe orifice 9 on the main pipeline 7 is connected to the thrombus collection tank in the thrombus collection device, and the second pipe orifice 10 on the main pipeline 7 is provided with an aspiration pipeline interface for connecting an aspiration catheter.

[0067] Furthermore, the suction on-off control mechanism 4 is used to control the on-off state of the main pipeline 7 between the suction catheter and the thrombus collection device. Optionally, the suction on-off control mechanism 4 can adopt a solenoid valve, a servo push-pull rod, a shutter structure, etc. Among them, the servo push-pull rod achieves the on-off effect by squeezing the pipeline; refer to Figure 4 the schematic diagram of a shutter structure shown in

[0068] Furthermore, the first pressure sensor 1 is arranged between the suction on-off control mechanism 4 and the suction catheter, and is used to measure the pressure value of the main pipeline 7 between the suction catheter and the thrombus collection device.

[0069] Furthermore, the third pressure sensor 3 is arranged on the main pipeline 7, and is used to measure the pressure value of the main pipeline 7 between the thrombus collection tank body and the vacuum pump.

[0070] Furthermore, both the first pressure sensor 1 and the third pressure sensor 3 are negative pressure sensors.

[0071] In one example, Figure 2 、 Figure 3 it is also shown that the perfusion on-off control mechanism 5 is arranged on the branch side pipeline 8 to connect the perfusion mechanism 6 to the main pipeline 7 between the suction catheter and the suction on-off control mechanism through the branch side pipeline 8. The perfusion on-off control mechanism 5 is used to control the on-off state between the perfusion mechanism 6 and the main pipeline 7. Optionally, the perfusion on-off control mechanism 5 can adopt a solenoid valve, a servo push-pull rod, a shutter structure, etc.

[0072] Furthermore, the third pipe orifice 11 of the branch side pipeline 8 is used to connect the perfusion liquid storage device, and the perfusion liquid storage device stores perfusion liquid. The perfusion mechanism 6 is used to transmit the perfusion liquid to the main pipeline 7 through the branch side pipeline 8.

[0073] Furthermore, the second pressure sensor 2 is arranged on the branch side pipeline 8 and is used to measure the pressure value on the branch side pipeline 8. In one example, the second pressure sensor 2 is a liquid pressure sensor.

[0074] In one example, Figure 3A processor is also shown, which is electrically connected to the first pressure sensor 1, the second pressure sensor 2, and the third pressure sensor 3. The processor is configured to identify whether a thrombus is aspirated by the aspiration catheter based on one or more of the pressure values collected by the first pressure sensor 1, the second pressure sensor 2, and the third pressure sensor 3, and / or identify the diameter value of the main pipeline, and the diameter value is negatively correlated with the on-off frequency corresponding to the aspiration on-off control mechanism. Specifically, based on the pressure difference between the first pressure sensor 1 and the third pressure sensor 3, it is possible to identify whether a thrombus is aspirated by the aspiration catheter, and / or identify the diameter value of the main pipeline. Specifically, based on the pressure value detected by any one of the first pressure sensor 1, the second pressure sensor 2, and the third pressure sensor 3, it is also possible to identify whether a thrombus is aspirated by the aspiration catheter, and / or identify the diameter value of the main pipeline.

[0075] In addition, the processor is also electrically connected to the aspiration on-off control mechanism 4, the perfusion on-off control mechanism 5, the perfusion mechanism 6, and the vacuum pump to control the aspiration on-off control mechanism 4, the perfusion on-off control mechanism 5, the perfusion mechanism 6, and the vacuum pump.

[0076] Optionally, the processor may adopt an MCU (Microcontroller Unit) processor.

[0077] Based on the above structure, the embodiments of the present invention provide functions that the cyclic aspiration device can achieve. Specifically:

[0078] (1) Intelligent identification of pipeline diameter.

[0079] After the first pipe orifice 9 on the main pipeline 7 is connected to the thrombus collection tank body, in the state where the aspiration on-off control mechanism 4 is fully open, the pressure difference between the first pressure sensor 1 and the third pressure sensor 3 is detected, which is equal to the pressure drop value during the vacuum aspiration process. The pressure drop value is related to the cross-sectional area and length of the main pipeline 7. On the premise of specifying the length of the main pipeline 7, the pressure drop value caused by the change in the cross-sectional area of the main pipeline 7 increases with the increase in the cross-sectional area of the main pipeline 7, and the vacuum pressure drop difference decreases, and the difference between the two pressure sensors also decreases.

[0080] By judging the pipeline diameter, the no-load (benchmark value for aspirating air) value of the product can be effectively calibrated, and the switching frequency of the aspiration on-off control mechanism 4 during the thrombus aspiration process can be determined.

[0081] (2) Thrombus fragmentation mode. In the thrombus fragmentation mode, there is an interlock relationship between the perfusion on-off control mechanism 5 and the aspiration on-off control mechanism 4. The interlock relationship means that the perfusion on-off control mechanism 5 controls the branch pipeline to be disconnected, and the aspiration on-off control mechanism 4 controls the main pipeline to be conducted; or the perfusion on-off control mechanism 5 controls the branch pipeline to be conducted, and the aspiration on-off control mechanism 4 controls the main pipeline to be disconnected.

[0082] See also Figure 5 A partial structural schematic diagram of a circulating suction device in a thrombus fragmentation mode is shown. In the suction state, the suction on-off control mechanism 4 is turned on and suction begins. When the pressure difference value between the first pressure sensor 1 and the third pressure sensor 3 is detected to be a thrombus (including three types: acute, mixed, and subacute thrombi, and basic data can be obtained in the laboratory), the perfusion mechanism 6 and the perfusion on-off control mechanism 5 are started; at the same time, the suction on-off control mechanism 4 is closed, and liquid is perfused into the suction catheter. The volume of the perfusion liquid is determined by the opening time of the perfusion mechanism 6 and the suction on-off control mechanism 4, and the volume is much smaller than the lumen volume in the pipeline. The perfusion liquid does not enter the human body, but only stays in the catheter, pushing the thrombus forward so that the thrombus is 1-3 mm away from the suction tube orifice.

[0083] Next, the perfusion mechanism 6 and the perfusion on-off control mechanism 5 are closed, and the suction on-off control mechanism 4 is opened at the same time, so that a small amount of perfusion liquid and blood as well as the thrombus at the tube mouth of the suction catheter are sucked into the suction catheter. Since the thrombus is 1-3 mm away from the tube mouth, when it contacts the tube mouth, the thrombus can be smashed into pieces after contacting and colliding with the tube mouth due to the inertia of negative pressure suction, thereby achieving the purpose of breaking the thrombus.

[0084] The functions provided by the perfusion mechanism 6 and the perfusion on-off control mechanism 5 in the embodiment of the present invention are: using a small amount of perfused liquid to push the thrombus away from the tube opening of the suction catheter, providing an initial distance for momentum conversion.

[0085] It should be noted that the irrigation liquid does not enter the human body during the suction process.

[0086] (3) Thrombus movement control mode. In the thrombus movement control mode, there is a linkage relationship between the perfusion on-off control mechanism and the suction on-off control mechanism. The linkage relationship is: the perfusion on-off control mechanism controls the conduction of the branch line, and the suction on-off control mechanism controls the conduction of the main line; the time that the perfusion on-off control mechanism controls the conduction of the branch line is less than the time that the suction on-off control mechanism controls the conduction of the main line.

[0087] In actual application, the thrombus moves in the main line along the negative pressure direction toward the thrombus collection tank. As the blood ring increases, the thrombus is attracted by greater negative pressure near the vacuum pump, and is less attracted by less negative pressure far away from the vacuum pump.

[0088] Based on this, see Figure 6 FIG. 1 is a schematic diagram of a partial structure of a cyclic suction device in a thrombus movement control mode, wherein the perfusion mechanism 6 and the perfusion on-off control mechanism 5 are opened. Figure 6 The liquid shown will be diverted partly toward the direction of the thrombus in the body to push the thrombus away, and partly close to the suction on-off control mechanism 4 to squeeze the thrombus through the suction on-off control mechanism 4.

[0089] Further, referring to Figure 7 the partial structural schematic diagram of the circulating aspiration device under another thrombus movement control mode shown in Figure 7 which indicates the movement direction of the perfusion liquid and also marks the mixing area of the perfusion liquid and the thrombus. It can be seen that the thrombus can be moved in two directions by the perfusion liquid, with a part being pushed back into the aspiration catheter and a part being squeezed into the thrombus collection tank body.

[0090] Further, the perfusion liquid can be physiological saline, etc. The flow inertia of the liquid is greater than that of the thrombus, which can better accelerate the flow of the thrombus towards the thrombus collection tank.

[0091] Because the thrombus is viscous, once it stops moving in the catheter, it will cause blockage of the aspiration catheter, thereby directly prolonging the operation time or terminating the operation, or replacing the instrument to increase the treatment cost. Based on this, each time, by controlling the opening time of the perfusion mechanism 6 and the perfusion on-off control mechanism 5, the opening time of the aspiration on-off control mechanism 4 is made greater than the opening time of the perfusion mechanism 6 and the perfusion on-off control mechanism 5, so as to control the thrombus to always maintain a reciprocating movement of one-way movement in the catheter. The frictional force is reduced to always keep the sliding friction between the thrombus and the aspiration pipeline, reducing the demand for negative pressure attraction, or improving the aspiration efficiency of negative pressure attraction under the same pressure.

[0092] (4) The perfusion mechanism operates continuously, the perfusion on-off control mechanism controls the branch pipeline to be continuously conducted, and the aspiration on-off control mechanism controls the main pipeline to be indirectly conducted; the amount of perfusion liquid provided by the perfusion mechanism during the period when the perfusion on-off control mechanism controls the branch pipeline to be conducted is less than the aspiration amount of the thrombus collection device during the period when the aspiration on-off control mechanism controls the main pipeline to be conducted. In one example, by controlling the perfusion on-off control mechanism to continuously conduct the branch pipeline, the perfusion mechanism can continuously provide perfusion liquid for the branch pipeline. By controlling the operating efficiency of the perfusion mechanism and changing the amount of perfusion liquid continuously provided by the perfusion mechanism for the branch pipeline, the amount of perfusion liquid is made less than the aspiration amount of the thrombus collection device during the period when the aspiration on-off control mechanism controls the main pipeline to be conducted, which can also reduce the frictional force to always keep the sliding friction between the thrombus and the aspiration pipeline, reducing the demand for negative pressure attraction, or improving the aspiration efficiency of negative pressure attraction under the same pressure.

[0093] (5) The perfusion mechanism is in continuous operation, and the perfusion mechanism and the perfusion on-off control mechanism are in a pressurized state; the perfusion volume of the perfusion mechanism is related to the time when the perfusion on-off control mechanism controls the conduction of the branch line, and the perfusion liquid volume of the perfusion mechanism is less than the single suction volume of the thrombus collection device. In one example, by changing the time when the perfusion on-off control mechanism controls the conduction of the branch line, the perfusion liquid volume provided by the perfusion mechanism to the branch line can be adjusted so that the perfusion liquid volume of the perfusion mechanism is less than the single suction volume of the thrombus collection device, and the friction force can be reduced to keep the sliding friction between the thrombus and the suction line at all times, thereby reducing the demand for negative pressure attraction, or improving the suction efficiency of negative pressure suction at the same pressure.

[0094] (6) Increase the flow rate of thrombus in the pipeline.

[0095] Due to the increase of the perfusion liquid, the relative flow rate of the mixed liquid of the thrombus and the perfusion liquid in the main pipe 7 is greatly increased, and the viscous state is changed to a mixed state, which can greatly reduce the operation time.

[0096] (7) Clear the suction catheter.

[0097] See also Figure 8 The schematic diagram of the partial structure of the circulating suction device in the suction catheter unblocking mode is shown. To unblock the suction catheter blocked by thrombus, the suction on-off control mechanism 4 is turned off, and the perfusion mechanism 6 and the perfusion on-off control mechanism 5 are started. The perfusion liquid can be used to flush the thrombus blocking the blood vessel back into the body to achieve the effect of unblocking the catheter. When the first pressure sensor 1 detects a low positive pressure value, it is determined that the suction catheter has been unblocked. Figure 9 A partial structural diagram of another circulating suction device in a dredging and suction catheter mode is shown, Figure 9 It shows that the pipeline is filled with perfusion fluid in the unblocked state, and the thrombus is cleared out of the catheter.

[0098] (8) Perfusion mode. The addition of perfusion function can directly perfuse the perfusion fluid into the body to reduce blood loss.

[0099] In one embodiment, the present invention also provides Figure 10 The specific structural schematic diagram of another circulating suction device shown in the figure, the aforementioned on-off control mechanism is an overall on-off control structure 12, the overall on-off control structure 12 adopts a two-position three-way valve, the two-position three-way valve is used to control the on-off state of the pipeline between the suction catheter and the thrombus collection device, and is used to control the on-off state of the pipeline between the perfusion mechanism 6 and the suction catheter. Figure 10 The working principle of the circulating suction device shown can be referred to the aforementioned embodiment, and the embodiment of the present invention will not be described in detail.

[0100] In addition, the circulating suction device further comprises a shell.

[0101] In one example, the housing is used to provide protection for the perfusion mechanism, the first pressure sensor, and the on-off control mechanism. That is, the cyclic suction device is used as an independent device and is connected to an external suction catheter and an external thrombus collection device. In one embodiment, the cyclic suction device at least includes a perfusion mechanism, a first pressure sensor, and an on-off control mechanism. Preferably, the cyclic suction device includes Figure 2 or Figure 10 each of the components shown.

[0102] In another example, the housing is used to provide protection for the perfusion mechanism 6, the first pressure sensor 1, the on-off control mechanism, and the thrombus collection device, that is, the cyclic suction device and the thrombus collection device are integrated into one body.

[0103] In summary, the cyclic suction device provided by the embodiments of the present invention at least has the following characteristics: ①Intelligently identify the catheter diameter and automatically call the optimal parameters according to the catheter; ②Thrombus fragmentation mode, which increases the thrombus fragmentation mode by using the movement inertia of the thrombus and the negative water hammer effect; ③Control the movement of the thrombus in the catheter: adjust the opening of the perfusion mechanism 6 and the perfusion valve to experimentally control the mixing ratio of blood and thrombus in the suction management; ④Increase the flow velocity of the thrombus in the pipeline; ⑤Unclog the suction catheter after it is blocked by the thrombus.

[0104] Based on the foregoing embodiments, the embodiments of the present invention provide a cyclic suction system, including the cyclic suction device provided by the foregoing embodiments.

[0105] Those skilled in the art can clearly understand that for the convenience and conciseness of description, the specific working process of the cyclic suction system described above can refer to the corresponding process in the foregoing embodiments and will not be described herein again.

[0106] In the description of the embodiments of the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" shall be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two components. For those skilled in the art, the specific meanings of the above terms in the present invention can be understood according to specific situations.

[0107] In the description of the present invention, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation to the present invention. In addition, the terms "first", "second", and "third" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance.

[0108] Finally, it should be noted that the above-described embodiments are only specific embodiments of the present invention, which are used to illustrate the technical solutions of the present invention, rather than to limit them. The protection scope of the present invention is not limited thereto. Although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that any person skilled in the art within the technical scope disclosed by the present invention can still modify the technical solutions described in the foregoing embodiments or can easily conceive of changes, or make equivalent replacements for some of the technical features; and these modifications, changes or replacements do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention, and should all be covered by the protection scope of the present invention. Therefore, the protection scope of the present invention should be determined by the protection scope of the claims.

Claims

1. A circulating suction device, characterized in that: include: A perfusion mechanism, a first pressure sensor and an on-off control mechanism; The on-off control mechanism is connected to the perfusion mechanism, the suction catheter, and the thrombus collection device through pipelines, and the first pressure sensor is arranged between the on-off control mechanism and the suction catheter; The on-off control mechanism is used to control the on-off state of the pipeline; the perfusion mechanism is used to provide perfusion liquid for the pipeline between the suction catheter and the on-off control mechanism; the first pressure sensor is used to measure the pressure value of the pipeline between the suction catheter and the on-off control mechanism; The pipeline includes a main pipeline and a branch pipeline, and the on-off control mechanism includes a suction on-off control mechanism and an infusion on-off control mechanism; The suction on-off control mechanism is arranged on the main pipeline, and the suction on-off control mechanism is used to control the on-off state of the main pipeline between the suction catheter and the thrombus collection device; the first pressure sensor is arranged between the suction on-off control mechanism and the suction catheter; The perfusion on-off control mechanism is arranged on the branch pipeline, so as to connect the perfusion mechanism to the main pipeline between the suction catheter and the suction on-off control mechanism through the branch pipeline, and the perfusion on-off control mechanism is used to control the on-off state between the perfusion mechanism and the main pipeline; The working mode of the circulating suction device includes a thrombus fragmentation mode, and the perfusion on-off control mechanism and the suction on-off control mechanism in the thrombus fragmentation mode are interlocked; the perfusion on-off control mechanism controls the disconnection of the branch pipeline, and the suction on-off control mechanism controls the conduction of the main pipeline; or, the perfusion on-off control mechanism controls the conduction of the branch pipeline, and the suction on-off control mechanism controls the disconnection of the main pipeline.

2. The circulating suction device according to claim 1, characterized in that: The working mode of the cyclic suction device includes a thrombus movement control mode, and the perfusion on-off control mechanism and the suction on-off control mechanism in the thrombus movement control mode are in a linkage relationship; The perfusion on-off control mechanism controls the conduction of the branch pipeline, and the suction on-off control mechanism controls the conduction of the main pipeline; The time during which the branch pipeline is turned on by the perfusion on-off control mechanism is shorter than the time during which the main pipeline is turned on by the suction on-off control mechanism.

3. The circulating suction device according to claim 1, characterized in that: The perfusion mechanism operates continuously, the perfusion on-off control mechanism controls the branch pipeline to be continuously connected, and the suction on-off control mechanism controls the main pipeline to be indirectly connected; The amount of perfusion liquid provided by the perfusion mechanism during the period when the perfusion on-off control mechanism controls the conduction of the branch pipeline is less than the amount of suction by the thrombus collection device during the period when the suction on-off control mechanism controls the conduction of the main pipeline.

4. The circulating suction device according to claim 1, characterized in that: The perfusion mechanism is in continuous operation, and the perfusion mechanism and the perfusion on-off control mechanism are in a pressurized state; The perfusion volume of the perfusion mechanism is related to the time during which the perfusion on-off control mechanism controls the conduction of the branch pipeline, and the perfusion liquid volume of the perfusion mechanism is less than the single aspiration volume of the thrombus collection device.

5. The circulating suction device according to claim 1, characterized in that: The circulating suction device also includes a second pressure sensor, which is arranged on the branch-side pipeline and is used to measure the pressure value on the branch-side pipeline.

6. The circulating suction device according to claim 1, characterized in that: The thrombus collection device comprises a thrombus collection tank body and a vacuum pump, and the thrombus collection tank body and the vacuum pump are connected via the main pipeline; The cyclic suction device further comprises a third pressure sensor, which is disposed on the main pipe and is used to measure the pressure value of the main pipe between the thrombus collection tank and the vacuum pump.

7. The circulating suction device according to claim 5 or 6, characterized in that: The cyclic suction device also includes a processor, which is electrically connected to the first pressure sensor, the second pressure sensor, and the third pressure sensor; The processor is used to identify whether the suction catheter has sucked a thrombus based on one or more of the pressure values ​​collected by the first pressure sensor, the second pressure sensor, and the third pressure sensor, and / or to identify the diameter value of the main line, wherein the diameter value is negatively correlated with the on-off frequency corresponding to the suction on-off control mechanism.

8. The circulating suction device according to claim 1, characterized in that: The on-off control mechanism is an integrated on-off control structure, and the integrated on-off control structure adopts a two-position three-way valve. The two-position three-way valve is used to control the on-off state of the pipeline between the suction catheter and the thrombus collection device, and is used to control the on-off state of the pipeline between the perfusion mechanism and the suction catheter.

9. The circulating suction device according to claim 1, characterized in that: The circulatory suction device also includes a shell, which is used to provide protection for the perfusion mechanism, the first pressure sensor and the on-off control mechanism; or, used to provide protection for the perfusion mechanism, the first pressure sensor, the on-off control mechanism and the thrombus collection device.

10. A circulating suction system, characterized in that: The circulating suction device comprises the circulating suction device described in any one of claims 1 to 9.

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