Loading device for anti-fatigue experiment of laboratory mouse

Abstract

The invention provides a load bearing device for an anti-fatigue experiment of a laboratory mouse. The load bearing device comprises a mounting structure and a plurality of balancing weights. The mounting structure can cover the tail of the laboratory mouse, and a plurality of mounting grooves are formed in the mounting structure. And the balancing weights are detachably mounted in the corresponding mounting grooves. And a balancing weight can be mounted in each mounting groove. And the weight of a single balancing weight is constant. The mounting structure wraps the tail of the laboratory mouse, the load of the laboratory mouse is changed by placing different numbers of balancing weights in different mounting grooves in the mounting structure, operation is convenient, and the load weight is easy to control.

Description

Technical Field

[0001] The invention relates to the technical field of experimental devices, and in particular to a weight-bearing device for an experimental mouse anti-fatigue experiment. Background Art

[0002] Anti-fatigue experiments are required to evaluate the efficacy of anti-fatigue drugs or foods, among which the weighted swimming test for experimental mice is the most widely used.

[0003] In the weighted swimming experiment of experimental mice, it is necessary to load a certain proportion of the body weight of lead sheets or lead blocks on the tail of the experimental mouse, and then put the experimental mouse into the water for swimming test. In practice, it is found that it takes a lot of time to cut the fixed weight of lead sheets or lead blocks. Generally speaking, it is necessary to cut and weigh the lead sheets or lead blocks of the target weight multiple times; and then fix the cut scattered lead sheets or lead blocks on the tail of the experimental mouse. The lead sheets can be clamped on the tail of the experimental mouse, and the lead blocks need to be fixed on the tail of the experimental mouse by ropes; and as the test progresses over multiple days, the weight of the experimental mouse changes. In order to obtain accurate test results, it is necessary to change the weight of the lead blocks or lead sheets on the tail of the experimental mouse according to the weight of the experimental mouse, which will further aggravate the above inconvenience. Summary of the invention

[0004] In view of the deficiencies in the prior art, the present invention provides a weight-bearing device for anti-fatigue experiments on experimental mice, thereby solving or at least alleviating one or more of the above-mentioned problems and other problems in the prior art.

[0005] The present invention provides a weight-bearing device for an anti-fatigue experiment of experimental mice, comprising:

[0006] A mounting structure, which can be wrapped around the tail of the experimental mouse and has a plurality of mounting grooves; and

[0007] A plurality of counterweight blocks are detachably mounted in corresponding mounting grooves.

[0008] Preferably, the mounting structure is an elastic fixing sleeve; at least one end of the fixing sleeve is open; the mounting groove is provided on the fixing sleeve; and the counterweight block can be snapped into the corresponding mounting groove.

[0009] Preferably, a tightening mechanism is also included; the mounting mechanism includes:

[0010] A connecting ring that can be placed on the outside of the tail of the experimental mouse; and

[0011] Two strip-shaped mounting belts, one end of each of the two strip-shaped mounting belts is connected to the connecting ring, and the two strip-shaped mounting belts are symmetrically arranged relative to the center line of the connecting ring;

[0012] The installation grooves are arranged on the strip-shaped installation belt and are distributed along the length direction thereof; the tightening mechanism is used to drive the two strip-shaped installation belts to fit on the tail of the experimental mouse from both sides.

[0013] Preferably, the strip mounting belt includes a magnetic strip mounting portion; one end of the strip mounting portion is connected to the connecting ring; the mounting groove is opened on the strip mounting portion; a plurality of the mounting grooves are distributed along the length direction of the strip mounting portion; and the counterweight block can be magnetically attracted by the mounting groove.

[0014] Preferably, the tightening mechanisms are provided with two or more;

[0015] The tightening mechanism comprises:

[0016] Two arc-shaped tightening plates, respectively located outside the two strip-shaped mounting portions; and

[0017] Two tightening belts, two ends of each tightening belt are respectively connected to two ends of the corresponding arc-shaped tightening plate;

[0018] The distance between the two arc-shaped tightening plates is adjustable; a tightening channel is formed between the tightening belt and the corresponding arc-shaped tightening plate; and the strip-shaped mounting portion passes through the tightening channel.

[0019] Preferably, at least one limiting hole is provided on the arc-shaped tightening plate; the limiting hole allows the counterweight block to pass through.

[0020] Preferably, the tightening mechanism also includes four limit blocks; every two of the limit blocks are located in the tightening channel and are connected to the inner wall of the arc-shaped tightening plate; a limit groove is formed between two adjacent limit blocks; the strip mounting portion is slidably matched with the corresponding limit groove; the tightening belt is used to limit the strip mounting portion to avoid separation of the strip mounting portion from the limit groove.

[0021] Preferably, the strip mounting belt further comprises:

[0022] A strip-shaped fitting portion, the strip-shaped fitting portion is connected to the strip-shaped mounting portion, and the strip-shaped fitting portion extends along the length direction of the strip-shaped mounting portion;

[0023] One side of the strip-shaped fitting portion abuts against the two limit blocks, and one side of the strip-shaped fitting portion facing away from the limit blocks abuts against the tightening belt.

[0024] Preferably, a side of the strip-shaped fitting portion facing away from the limiting block is a curved surface;

[0025] The tightening belt comprises:

[0026] An arc-shaped limiting portion, wherein a side of the arc-shaped limiting portion facing the limiting block is an arc surface, and a side of the arc-shaped limiting portion facing the limiting block is slidably matched with a side of the strip-shaped fitting portion away from the limiting block; and

[0027] Two elastic connection parts, the two elastic connection parts are respectively connected to the two ends of the arc-shaped limiting part, and one end of the elastic connection part away from the arc-shaped limiting part is connected to the end of the arc-shaped tightening plate.

[0028] Preferably, the tightening mechanism further comprises two tightening assemblies; the two tightening assemblies are located on both sides of the arc-shaped tightening plate;

[0029] The tightening assembly comprises:

[0030] A first tightening cylinder, one end of which is connected to the end of the arc-shaped tightening plate, and the other end of which is internally connected to a coaxial first limiting ring;

[0031] A second tightening cylinder is arranged in parallel with the first tightening cylinder, one end of which is connected to the other tightening plate, and a coaxial second limiting ring is connected inside the end;

[0032] A first sliding ring, which is slidably sleeved outside the first tightening tube and connected to the second tightening tube; and

[0033] A second sliding ring, slidably mounted outside the second tightening tube and connected to the first tightening tube;

[0034] When the first tightening tube and the second tightening tube move away from each other, the first sliding ring and the second sliding ring can abut against each other; docking windows are respectively provided on the surfaces of the first tightening tube and the second tightening tube that are close to each other; the end of the first tightening tube away from the first limiting ring can be slid into the counterweight block; the end of the second tightening tube away from the second limiting ring can be slid into the counterweight block; the counterweight block in the first tightening tube and the counterweight block in the second tightening tube can be magnetically attracted to each other; the counterweight block can abut against the first limiting ring and the second limiting ring.

[0035] Compared with the prior art, the present invention has the following beneficial effects:

[0036] In the technology of the present invention, the mounting structure is covered on the tail of the experimental mouse, and the weight of the experimental mouse is changed by placing different numbers of counterweight blocks in different mounting grooves on the mounting structure. The operation is convenient and the weight is easy to control. BRIEF DESCRIPTION OF THE DRAWINGS

[0037] In order to more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following is a brief introduction to the drawings required for the specific embodiments or the description of the prior art. In all the drawings, similar elements or parts are generally identified by similar reference numerals. In the drawings, the elements or parts are not necessarily drawn according to the actual scale.

[0038] Figure 1 A three-dimensional diagram of a weight-bearing device for anti-fatigue experiments on experimental mice in one embodiment of the present invention;

[0039] Figure 2 for Figure 1 Another stereogram of

[0040] Figure 3 for Figure 2 Another stereogram of (without connecting ring);

[0041] Figure 4 for Figure 1 A three-dimensional diagram of the tightening mechanism;

[0042] Figure 5 for Figure 4 Another stereogram of .

[0043] Reference numerals:

[0044] 10. Installation structure; 11. Installation groove; 12. Connection ring; 13. Strip installation belt; 131. Strip installation part; 132. Strip fitting part;

[0045] 20. Counterweight;

[0046] 30. Tightening mechanism; 31. Arc-shaped tightening plate; 32. Tightening belt; 321. Arc-shaped limiting portion; 322. Elastic connecting portion; 33. Tightening channel; 34. Limiting hole; 35. Limiting block; 36. Limiting groove; 37. Tightening assembly; 371. First tightening cylinder; 372. First limiting ring; 373. Second tightening cylinder; 374. Second limiting ring; 375. First sliding ring; 376. Second sliding ring; 377. Docking window. DETAILED DESCRIPTION

[0047] The following embodiments of the technical solution of the present invention are described in detail in conjunction with the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the present invention, and are therefore only used as examples, and cannot be used to limit the protection scope of the present invention.

[0048] It should be noted that, unless otherwise specified, the technical terms or scientific terms used in this application should have the common meanings understood by those skilled in the art to which the present invention belongs.

[0049] In the description of the present application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the present invention.

[0050] In addition, the terms "first", "second", etc. are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. In the description of the present invention, the meaning of "plurality" is more than two, unless otherwise clearly and specifically defined.

[0051] In this application, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0052] In the present application, unless otherwise clearly specified and limited, a first feature being “above” or “below” a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being “above”, “above”, and “above” a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being “below”, “below”, and “below” a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0053] See also Figures 1 to 5 This embodiment provides a weight-bearing device for an anti-fatigue experiment on experimental mice, including a mounting structure 10 and a plurality of counterweight blocks 20.

[0054] The mounting structure 10 can be wrapped around the tail of the experimental mouse, and a plurality of mounting slots 11 are provided on the mounting structure 10. The counterweight block 20 can be detachably mounted in the corresponding mounting slot 11. One counterweight block 20 can be mounted in each mounting slot 11. The weight of a single counterweight block 20 is constant.

[0055] During the swimming experiment on experimental mice, weights are placed on the tails of the experimental mice. Lead blocks and lead sheets are difficult to fix, and the weight of the lead blocks and lead sheets is difficult to control when cutting them.

[0056] In this embodiment, the mounting structure 10 is wrapped around the tail of the experimental mouse, and different numbers of counterweights 20 are placed in different mounting slots 11 on the mounting structure 10 to change the weight of the experimental mouse. The operation is convenient and the weight is easy to control.

[0057] In one embodiment, the mounting structure 10 is an elastic fixed sleeve. At least one end of the fixed sleeve is open. The mounting groove 11 is provided on the fixed sleeve. The counterweight 20 can be snapped into the corresponding mounting groove 11. Specifically, the fixed sleeve can be made of silicone or rubber material, etc., and the size of the mounting groove 11 is slightly smaller than the counterweight 20, so that the counterweight 20 can be stuck after being inserted into the mounting groove 11. In addition, the interior of the mounting groove 11 can be an arc surface, and correspondingly, the counterweight 20 can be spherical. In addition, the fixed sleeve can be thinner as a whole, and the local part used to open the mounting groove 11 is convex, so that the overall weight can be easily controlled.

[0058] In this embodiment, the fixing sleeve is put on the tail of the experimental mouse from its open end, and the tail of the experimental mouse is covered and fixed by using its elasticity, and then a sufficient number of counterweights 20 are installed in the corresponding installation grooves 11 as needed.

[0059] In one embodiment, the weight-bearing device for anti-fatigue experiment on experimental mice further includes a tightening mechanism 30 .

[0060] The mounting mechanism comprises a connecting ring 12 and two strip-shaped mounting belts 13 .

[0061] The connecting ring 12 can be sleeved on the outside of the tail of the experimental mouse. One end of the two strip-shaped mounting belts 13 is connected to the connecting ring 12, and the two strip-shaped mounting belts 13 are arranged symmetrically relative to the center line of the connecting ring 12. The mounting grooves 11 are provided on the strip-shaped mounting belts 13 and distributed along the length direction thereof, and the tightening mechanism 30 is used to drive the two strip-shaped mounting belts 13 to fit on the tail of the experimental mouse from both sides. The connecting ring 12 can be elastic so that the connecting ring 12 can be fixed on the tail of the experimental mouse; in addition, a clamping hoop can be provided outside the connecting ring 12, and the clamping hoop is used to clamp the connecting ring 12 on the tail of the experimental mouse.

[0062] In practice, it is found that when the tail of an experimental mouse is inserted into a relatively soft and elastic fixing sleeve, since the tail of the experimental mouse is soft and curved, the fixing sleeve must be ensured to fit the tail of the experimental mouse and better cover the tail of the experimental mouse without falling off. This makes the inner diameter of the fixing sleeve itself smaller, and the tail of the experimental mouse cannot easily pass through the entire fixing sleeve.

[0063] In this embodiment, the tail of the experimental mouse only needs to pass through the connecting ring 12 and then be located between the two strip-shaped mounting belts 13. The distance between the two strip-shaped mounting belts 13 is relatively wide, and since there are only two strip-shaped mounting belts 13, it is not difficult for the tail of the experimental mouse to pass between the two strip-shaped mounting belts 13. Then, the two strip-shaped mounting belts 13 are tightened to make them close to each other and then abut against the tail of the experimental mouse from both sides, so that the two strip-shaped mounting belts 13 are fixed on the tail of the experimental mouse. Since there are only two strip-shaped mounting belts 13, the operation is convenient, saving time and effort.

[0064] In addition, by attaching the two strip-shaped mounting belts 13 to both sides of the tail of the experimental mouse through the tightening mechanism 30, it is possible to avoid the scattered strip-shaped mounting belts 13 causing resistance when the experimental mouse swims, thereby preventing inaccurate experimental results.

[0065] In one embodiment, the strip mounting belt 13 includes a magnetic strip mounting portion 131. One end of the strip mounting portion 131 is connected to the connecting ring 12. The mounting groove 11 is provided on the strip mounting portion 131. A plurality of mounting grooves 11 are distributed along the length direction of the strip mounting portion 131. The counterweight 20 can be magnetically attracted by the mounting groove 11. The strip mounting portion 131 can be made of magnetic rubber. The inner surface of the mounting groove 11 can be a spherical surface, the counterweight 20 can be spherical, and the counterweight 20 can be a magnetic bead.

[0066] In this embodiment, the bar-shaped mounting portion 131 and the counterweight 20 are magnetically attracted to each other, which makes it more convenient to control the weight of the experimental mouse.

[0067] In one embodiment, more than two tightening mechanisms 30 are provided (only one is shown in the figure), and the tightening mechanism 30 includes two arc-shaped tightening plates 31 and two tightening belts 32 .

[0068] The two arc-shaped tightening plates 31 are respectively located outside the two strip-shaped mounting portions 131. The two ends of each tightening belt 32 are respectively connected to the two ends of the corresponding arc-shaped tightening plate 31. The distance between the two arc-shaped tightening plates 31 is adjustable. A tightening channel 33 is formed between the tightening belt 32 and the corresponding arc-shaped tightening plate 31, and the strip-shaped mounting portion 131 passes through the tightening channel 33. The two tightening belts 32 are between the two arc-shaped tightening plates 31. The inner side surface of the arc-shaped tightening plate 31 is an arc surface and can fit with the outer arc surface of the strip-shaped mounting portion 131.

[0069] In this embodiment, when the tail of the experimental mouse is not placed between the two strip-shaped mounting parts 131, under the adjustment of the two arc-shaped tightening plates 31, there is a certain distance between the two strip-shaped mounting parts 131, so as to facilitate the subsequent passage of the tail of the experimental mouse between the two strip-shaped mounting parts 131. After the distance between the two arc-shaped tightening plates 31 is reduced, the two strip-shaped mounting parts 131 are fitted and fixed to the tail of the experimental mouse. Since there are more than two tightening mechanisms 30, the fixing of the strip-shaped mounting parts 131 to the tail of the experimental mouse is achieved at multiple locations, thereby reducing the probability of the device and the experimental mouse being separated. In addition, the arc-shaped tightening plate 31 can move along the length direction of the strip-shaped mounting part 131, so that the position where the device is fixed to the laboratory can be adjusted.

[0070] In one embodiment, the two arc-shaped tightening plates 31 move to the appropriate position along the tail of the experimental mouse and then approach each other, thereby fixing the device on the tail of the experimental mouse. At the same time, the configuration block is passed through the limiting hole 34 on the arc-shaped tightening plate 31 and is magnetically fixed to the corresponding mounting groove 11. The counterweight block 20 can limit the arc-shaped tightening plate 31 to prevent the arc-shaped tightening plate 31 from moving along the length direction of the tail of the experimental mouse when the experimental mouse swims, causing the device to be separated from the tail of the laboratory. That is, the counterweight block 20 can be used for counterweighting and for limiting the position of the arc-shaped tightening plate 31. In addition, after the counterweight blocks 20 are magnetically attracted in the mounting grooves 11 on both sides of the arc-shaped tightening plate 31, they can be counteracted with the arc tightening, thereby further limiting the arc-shaped tightening plate 31.

[0071] In one embodiment, the tightening mechanism 30 also includes four limit blocks 35; every two limit blocks 35 are located in the tightening channel 33 and are connected to the inner wall of the arc-shaped tightening plate 31; a limit groove 36 is formed between two adjacent limit blocks 35; the strip mounting portion 131 is slidably matched with the corresponding limit groove 36; the tightening belt 32 is used to limit the strip mounting portion 131 to avoid separation of the strip mounting portion 131 from the limit groove 36.

[0072] In this embodiment, in order to maintain the fit with the tail of the experimental mouse, the strip-shaped mounting portion 131 gradually decreases from one end of the connecting ring 12 to the other end thereof. Therefore, the size of the tightening channel 33 is slightly larger than the strip-shaped mounting portion 131. In order to prevent the strip-shaped mounting portion 131 from sliding laterally in the tightening channel 33, a limiting groove 36 is provided, so that the device can be stably fixed to the tail of the experimental mouse.

[0073] In one embodiment, the strip-shaped mounting belt 13 further includes a strip-shaped fitting portion 132 .

[0074] The strip-shaped fitting portion 132 is connected to the strip-shaped mounting portion 131 and extends along the length direction of the strip-shaped mounting portion 131. One side of the strip-shaped fitting portion 132 abuts against two limit blocks 35, and one side of the strip-shaped fitting portion 132 away from the limit blocks 35 abuts against the tightening belt 32.

[0075] In this embodiment, the strip-shaped fitting portion 132 can increase the contact area with the tail of the experimental mouse, so that the device and the tail of the experimental mouse are fixed more firmly. In addition, the strip-shaped fitting portion 132 can make the strip-shaped mounting portion 131 always located in the limiting groove 36, so that the positions of the two strip-shaped mounting portions 131 and the two strip-shaped fitting portions 132 can be controlled under the control of the arc-shaped tightening plate 31, which is convenient for the subsequent passage of the tail of the experimental mouse.

[0076] In one embodiment, a surface of the strip-shaped fitting portion 132 facing away from the limiting block 35 is a curved surface.

[0077] The tightening belt 32 includes an arc-shaped limiting portion 321 and two elastic connecting portions 322 .

[0078] The side of the arc-shaped limiting portion 321 facing the limiting block 35 is an arc surface, and the side of the arc-shaped limiting portion 321 facing the limiting block 35 is slidably matched with the side of the strip-shaped fitting portion 132 away from the limiting block 35. The two elastic connecting portions 322 are respectively connected to the two ends of the arc-shaped limiting portion 321, and the end of the elastic connecting portion 322 away from the arc-shaped limiting portion 321 is connected to the end of the arc-shaped tightening plate 31. Specifically, the arc-shaped limiting portion 321 can maintain its arc-shaped structure. The tightening belt 32 is roughly in a "W" shape.

[0079] In this embodiment, under the pulling of the two elastic connecting parts 322, the arc-shaped limiting part 321 applies an external force to the strip-shaped fitting part 132, thereby ensuring that the strip-shaped mounting part 131 is located in the mounting groove 11. The angle formed at the connection between the two elastic connecting parts 322 and the arc-shaped limiting part 321 is toward the arc-shaped tightening plate 31, and both angles are less than 180 degrees, so that the two sides of the strip-shaped fitting part 132 are limited when they are against the elastic connecting parts 322, so that the strip-shaped fitting part 132 will not move laterally. In addition, the inner side of the arc-shaped limiting part 321 is also arc-shaped, so that it fits better with the tail of the experimental mouse, which is conducive to fixation.

[0080] In one embodiment, the tightening mechanism 30 further includes two tightening assemblies 37; the two tightening assemblies 37 are located on both sides of the arc-shaped tightening plate 31;

[0081] The tightening assembly 37 includes a first tightening cylinder 371 , a second tightening cylinder 373 , a first sliding ring 375 and a second sliding ring 376 .

[0082] One end of the first tightening cylinder 371 is connected to the end of the arc-shaped tightening plate 31, and the other end thereof is connected with a coaxial first limiting ring 372. The second tightening cylinder 373 is arranged in parallel with the first tightening cylinder 371, and one end of the second tightening cylinder 373 is connected to another arc-shaped tightening plate 31, and the coaxial second limiting ring 374 is connected to the end thereof. The first sliding ring 375 is slidably sleeved outside the first tightening cylinder 371, and the first sliding ring 375 is connected to the second tightening cylinder 373. The second sliding ring 376 is slidably sleeved outside the second tightening cylinder 373, and the second sliding ring 376 is connected to the first tightening cylinder 371.

[0083] When the first tightening cylinder 371 and the second tightening cylinder 373 are away from each other, the first sliding ring 375 and the second sliding ring 376 can abut against each other. A docking window 377 is respectively provided on the surface of the first tightening cylinder 371 and the second tightening cylinder 373 that are close to each other. The end of the first tightening cylinder 371 away from the first limiting ring 372 can be slid into the counterweight 20. The end of the second tightening cylinder 373 away from the second limiting ring 374 can be slid into the counterweight 20. The counterweight 20 in the first tightening cylinder 371 and the counterweight 20 in the second tightening cylinder 373 can be magnetically attracted to each other. The counterweight 20 can abut against the first limiting ring 372 and the second limiting ring 374. Specifically, the counterweight 20 has magnetism, the first tightening cylinder 371 and the second tightening cylinder 373 can be hollow structures, and the counterweight 20 can slide along the axial direction in the first tightening cylinder 371 and the second tightening cylinder 373. The counterweights 20 in the first tightening cylinder 371 and the second tightening cylinder 373 are spherical and can pass through the docking window 377 to abut against each other to enhance the magnetic attraction effect. In addition, a block removal window is provided on the side of the first tightening cylinder 371 and the second tightening cylinder 373 that are away from each other, and a portion of the counterweight 20 protrudes outward from the block removal window. The counterweight 20 can be pushed at the block removal window to facilitate the counterweight 20 to be taken out of the first tightening cylinder 371 and the second tightening cylinder 373. Since the counterweight 20 in the first tightening cylinder 371 and the counterweight 20 in the second tightening cylinder 373 are docked in the docking window 377, the counterweight 20 in the second tightening cylinder 373 is not easy to be separated from the second tightening cylinder 373, so that the first tightening cylinder 371 and the second tightening cylinder 373 remain relatively still.

[0084] In this embodiment, Figure 5, the counterweight 20 is placed from the same side end (upper end in the figure) of the first tightening cylinder 371 and the second tightening cylinder 373, and when placing the counterweight 20, one counterweight 20 is placed in the first tightening cylinder 371 first, and then the other counterweight 20 is placed in the second tightening cylinder 373. Under the action of gravity, the two counterweights 20 stop at the bottom of the first tightening cylinder 371 and the second tightening cylinder 373 and are magnetically attracted to each other. Subsequently, the counterweight 20 can be placed in the first tightening cylinder 371 and the second tightening cylinder 373 in this order. Under the restriction of the first sliding ring 375 and the second sliding ring 376, the first tightening cylinder 371 and the second tightening cylinder 373 can slide closer to or away from each other, so that the arc-shaped tightening plates 31 on both sides can move closer to or away from each other. The first sliding ring 375 and the second sliding ring 376 can also prevent the first tightening cylinder 371 and the second tightening cylinder 373 from detaching from each other. The multiple counterweights 20 in the first tightening tube 371 and the second tightening tube 373 are magnetically attracted to each other, so that the distance between the arc-shaped tightening plates 31 on both sides remains unchanged, so that the device can be fixed on the tail of the experimental mouse.

[0085] In the description of the present invention, a large number of specific details are described. However, it is understood that embodiments of the present invention can be practiced without these specific details. In some instances, well-known methods, structures and techniques are not shown in detail so as not to obscure the understanding of this description.

[0086] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein by equivalents. These modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present invention, and they should all be included in the scope of the claims and specification of the present invention.

Claims

1. A weight-bearing device for anti-fatigue experiments on experimental mice, characterized in that: include: A mounting structure (10), wherein the mounting structure (10) can be wrapped around the tail of the experimental mouse and is provided with a plurality of mounting grooves (11); as well as A plurality of counterweight blocks (20), wherein the counterweight blocks (20) are detachably mounted in corresponding mounting grooves (11).

2. A weight-bearing device for anti-fatigue experiment of experimental mice as claimed in claim 1, characterized in that: The mounting structure (10) is an elastic fixed sleeve; at least one end of the fixed sleeve is open; the mounting groove (11) is provided on the fixed sleeve; and the counterweight (20) can be snap-fitted into the corresponding mounting groove (11).

3. A weight-bearing device for anti-fatigue experiment of experimental mice as claimed in claim 1, characterized in that: It also includes a tightening mechanism (30); the installation mechanism includes: A connecting ring (12) can be sleeved on the outside of the tail of the experimental mouse; and Two strip-shaped mounting belts (13), one end of each of the two strip-shaped mounting belts (13) being connected to the connecting ring (12), and the two strip-shaped mounting belts (13) being symmetrically arranged relative to the center line of the connecting ring (12); The installation grooves (11) are provided on the strip-shaped installation belt (13) and are distributed along the length direction thereof; the tightening mechanism (30) is used to drive the two strip-shaped installation belts (13) to fit onto the tail of the experimental mouse from both sides.

4. A weight-bearing device for anti-fatigue experiment of experimental mice as claimed in claim 3, characterized in that: The strip-shaped mounting belt (13) comprises a magnetic strip-shaped mounting portion (131); one end of the strip-shaped mounting portion (131) is connected to the connecting ring (12); the mounting groove (11) is provided on the strip-shaped mounting portion (131); a plurality of the mounting grooves (11) are distributed along the length direction of the strip-shaped mounting portion (131); and the counterweight (20) can be magnetically attracted by the mounting groove (11).

5. A weight-bearing device for anti-fatigue experiment of experimental mice as claimed in claim 4, characterized in that: The tightening mechanisms (30) are provided with more than two; The tightening mechanism (30) comprises: Two arc-shaped tightening plates (31), respectively located outside the two strip-shaped mounting portions (131); and Two tightening belts (32), two ends of each tightening belt (32) are respectively connected to two ends of the corresponding arc-shaped tightening plate (31); The distance between the two arc-shaped tightening plates (31) is adjustable; a tightening channel (33) is formed between the tightening belt (32) and the corresponding arc-shaped tightening plate (31); and the strip-shaped mounting portion (131) passes through the tightening channel (33).

6. A weight-bearing device for anti-fatigue experiment of experimental mice as claimed in claim 5, characterized in that: The arc-shaped tightening plate (31) is provided with one or more limiting holes (34); the limiting holes (34) are capable of allowing the counterweight block (20) to pass through.

7. A weight-bearing device for anti-fatigue experiment of experimental mice as claimed in claim 6, characterized in that: The tightening mechanism (30) further comprises four limit blocks (35); every two limit blocks (35) are located in the tightening channel (33) and are connected to the inner wall of the arc-shaped tightening plate (31); a limit groove (36) is formed between two adjacent limit blocks (35); the strip-shaped mounting portion (131) is slidably matched with the corresponding limit groove (36); and the tightening belt (32) is used to limit the strip-shaped mounting portion (131) to prevent the strip-shaped mounting portion (131) from being separated from the limit groove (36).

8. A weight-bearing device for anti-fatigue experiment of experimental mice as claimed in claim 7, characterized in that: The strip-shaped mounting belt (13) further comprises: A strip-shaped fitting portion (132), the strip-shaped fitting portion (132) being connected to the strip-shaped mounting portion (131), and the strip-shaped fitting portion (132) extending along the length direction of the strip-shaped mounting portion (131); One side of the strip-shaped fitting portion (132) abuts against the two limiting blocks (35), and one side of the strip-shaped fitting portion (132) facing away from the limiting blocks (35) abuts against the tightening belt (32).

9. A weight-bearing device for anti-fatigue experiment of experimental mice as claimed in claim 8, characterized in that: The side of the strip-shaped fitting portion (132) facing away from the limiting block (35) is a curved surface; The tightening belt (32) comprises: an arc-shaped limiting portion (321), wherein a side of the arc-shaped limiting portion (321) facing the limiting block (35) is an arc surface, and a side of the arc-shaped limiting portion (321) facing the limiting block (35) is slidably matched with a side of the strip-shaped fitting portion (132) facing away from the limiting block (35); and Two elastic connecting parts (322), the two elastic connecting parts (322) are respectively connected to the two ends of the arc-shaped limiting part (321), and one end of the elastic connecting part (322) away from the arc-shaped limiting part (321) is connected to the end of the arc-shaped tightening plate (31).

10. A weight-bearing device for anti-fatigue experiment of experimental mice as claimed in claim 9, characterized in that: The tightening mechanism (30) further comprises two tightening assemblies (37); the two tightening assemblies (37) are located on both sides of the arc-shaped tightening plate (31); The tightening assembly (37) comprises: A first tightening cylinder (371), one end of which is connected to the end of the arc-shaped tightening plate (31), and the other end of which is internally connected to a coaxial first limiting ring (372); A second tightening cylinder (373) is arranged in parallel with the first tightening cylinder (371), one end of which is connected to the other tightening plate, and a coaxial second limiting ring (374) is connected inside the end; A first sliding ring (375) is slidably mounted outside the first tightening tube (371) and connected to the second tightening tube (373); and A second sliding ring (376) is slidably mounted outside the second tightening tube (373) and connected to the first tightening tube (371); When the first tightening tube (371) and the second tightening tube (373) move away from each other, the first sliding ring (375) and the second sliding ring (376) can abut against each other; a docking window (377) is respectively provided on the surface of the first tightening tube (371) and the second tightening tube (373) that are close to each other; the end of the first tightening tube (371) away from the first limiting ring (372) can be slidably placed in the counterweight (20); the end of the second tightening tube (373) away from the second limiting ring (374) can be slidably placed in the counterweight (20); the counterweight (20) in the first tightening tube (371) and the counterweight (20) in the second tightening tube (373) can be magnetically attracted to each other; the counterweight (20) can abut against the first limiting ring (372) and the second limiting ring (374).

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