Rapid sampling equipment for clinical pharmaceutical experiments
By designing fast sampling equipment for fixed mechanisms and storage mechanisms, the problem of unstable connection of modular interfaces of existing equipment is solved, flexible switch of probes and efficient and accurate storage of samples are achieved, and sampling efficiency and sample quality are improved.
Patent Information
- Application Number
- CN202411936238.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-26
- Publication Date
- 2025-04-29
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
The modular interface connection of the existing rapid sampling equipment for clinical pharmacy experiments is not tight or stable enough, resulting in looseness, leakage or mismatch during the sampling process, affecting sampling efficiency and accuracy.
A quick sampling device including a fixing mechanism and a storage mechanism is designed. Through the combination of fixing mechanism one and fixing mechanism two, sampling needles of different sizes, shapes and materials can be easily installed and fixed, and samples can be sorted and stored and precisely cooled through the insulation tank of the storage mechanism and multiple storage tanks.
It realizes flexible switching and stable installation of different probes, improving sampling efficiency and accuracy; through classified storage and precise cooling processing, the stability of sample quality is ensured, and reliable sample acquisition and storage guarantee is provided for clinical pharmacy experiments.
Smart Images

Figure CN119901534A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of clinical pharmaceutical equipment, in particular to a rapid sampling device for clinical pharmaceutical experiments. Background Art
[0002] Clinical pharmacy experiments are scientific experiments that focus on studying the absorption, distribution, metabolism, excretion, efficacy and safety of drugs in the human body. They aim to optimize drug treatment plans and improve patient efficacy and medication safety. They cover new drug development, bioeffectiveness verification, drug application for special populations, optimization of individualized treatment plans, drug interactions and adverse reaction monitoring. Through experimental analysis of the pharmacological properties and clinical manifestations of drugs, clinical pharmacy experiments provide an important scientific basis for precision medicine, rational drug use and innovative drug research and development, and have far-reaching significance for improving medical quality.
[0003] Rapid sampling equipment for clinical pharmacy experiments is a device used to quickly and accurately collect liquid or biological samples in clinical pharmacy experiments. It aims to efficiently obtain experimental data required for drug metabolism or efficacy research. Most of the equipment is composed of sampling modules, negative pressure drive devices, transmission pipelines, sample storage systems, automatic control systems and monitoring units. Its core structure includes the precise connection between the micro-sampling probe and the flexible pipeline, which is used to quickly complete the pollution-free transmission and storage of samples. The equipment integrates an intelligent control interface and multi-dimensional sensing technology to achieve integrated operations of parameter setting, sample collection and dynamic monitoring.
[0004] In the prior art, the collection of high-viscosity liquids, particle suspensions or small-volume precision samples often requires probes of different sizes, shapes and materials, while traditional equipment is usually equipped with sampling probes of fixed specifications that cannot be flexibly switched, resulting in reduced sampling efficiency and accuracy. The equipment in the prior art is designed with a modular structure to meet the needs of rapid switching of different probes. Although the modular interface is flexible, the connection structure between modules may not be tight or stable enough, which may lead to looseness, leakage or mismatch during operation. Summary of the invention
[0005] In view of the shortcomings of the prior art, the present invention provides a rapid sampling device for clinical pharmaceutical experiments, which solves the problems of the prior art devices by designing a modular structure, so as to meet the rapid switching of different probes. Although the modular interface is flexible, the connection structure between modules may not be tight or stable enough, which may lead to looseness, leakage or mismatch during operation.
[0006] To achieve the above objectives, the present invention is implemented through the following technical solutions: A rapid sampling device for clinical pharmaceutical experiments, comprising a sampling box, a control panel is provided on the front side of the sampling box, a fixing mechanism 1 is provided on the side of the interior of the sampling box away from the control panel, a sampling needle is installed on the side of the fixing mechanism 1 close to the control panel, a peristaltic pump is connected to the top of the sampling needle through a pipeline, and a storage mechanism is connected to the end of the peristaltic pump away from the sampling needle through a pipeline, two fixing mechanisms 2 are provided on the bottom side of the interior of the sampling box, and a disinfection mechanism is provided inside the sampling box;
[0007] The fixing mechanism 1 includes a protective shell, which is slidably connected to the inside of a side of the sampling box away from the control panel, the top of the protective shell is electrically connected to a sensor 1, an electric push rod 1 is installed inside the protective shell, and the electric push rod 1 is fixedly connected to a moving block at one end close to the sampling needle, driving blocks are fixed on the left and right sides of the moving block, and a movable block is slidably connected to the outer periphery of the driving block, a connecting rod is fixed to a side of the movable block close to the sampling needle, and the end of the connecting rod away from the movable block is connected to a splint through an installation component, the movable block is slidably connected to a limiting rod on the inside of a side close to the connecting rod, and limiting blocks are installed on the front and rear sides of the limiting rod, and moving components are provided on the left and right sides of the end of the protective shell away from the sampling needle.
[0008] Preferably, the storage mechanism includes a heat-insulating tank, which is installed at the end of the peristaltic pump away from the sampling needle through a pipeline, and a plurality of storage tanks evenly distributed in a circle are installed inside the heat-insulating tank, a cooling pipe is provided on the outer periphery of the storage tank, one end of the cooling pipe is connected to a cooler, a delivery pipe is installed at the bottom of the storage tank, a slide is fixed on the outer periphery of the delivery pipe, and a preservation component is provided at the end of the delivery pipe away from the storage tank.
[0009] Preferably, the second fixing mechanism includes a second electric push rod, which is fixed inside the sampling box, a connecting plate is fixed to one end of the second electric push rod close to the sampling needle, and a rubber ring is fixed to the side of the connecting plate away from the second electric push rod.
[0010] Preferably, the disinfection mechanism includes a connecting shell, which is slidably connected to the interior of the sampling box, an electric slider one is fixed to the side of the connecting shell away from the sampling needle, an electric push rod three is fixed to the internal top side of the connecting shell, a movable frame is fixed to the internal top side of the electric push rod three away from the connecting shell, tooth plates are fixed on both sides of the movable frame's end close to the sampling needle, rotating shafts are fixed on both sides of the interior of the connecting shell, gears are fixed on the outer periphery of the rotating shaft, the gears are meshed with the tooth plates, and ultraviolet lamps are fixed on the opposite sides of the two rotating shafts.
[0011] Preferably, the mounting assembly includes a fastening bolt, which is threadedly connected to an end of the connecting rod away from the movable block, and a mounting block is fixed to a side of the clamping plate close to the connecting rod, and the outer periphery of the fastening bolt is threadedly connected to the inside of the mounting block.
[0012] Preferably, the two movable components each include an electric slider 2, and the two electric sliders 2 are respectively fixedly connected to the left and right sides of the protective shell, and sliding rods are fixed on the left and right sides of the interior of the sampling box, and the two electric sliders 2 are respectively slidably connected to the outer periphery of the two sliding rods.
[0013] Preferably, the preservation component includes a preservation tank, which is arranged at one end of the conveying pipe away from the storage tank, and a second sensor is arranged on the side of the preservation tank away from the slide. A placement rack is slidably provided inside the side of the sampling box close to the control panel, and the second sensor is installed inside the placement rack.
[0014] Preferably, a rubber pad is fixed to a side of the clamping plate away from the connecting rod, and the rubber pad slides on the outer periphery of the sampling needle on a side away from the connecting rod.
[0015] Preferably, the cooler is slidably connected to the inside of the sampling box, and the side of the insulation tank away from the peristaltic pump is fixed inside the side of the sampling box close to the control panel.
[0016] Preferably, a side of the limiting rod away from the movable block is fixed inside the protective shell.
[0017] The present invention provides a rapid sampling device for clinical pharmaceutical experiments. It has the following beneficial effects:
[0018] 1. The present invention can conveniently install and fix sampling needles of different sizes, shapes and materials through fixing mechanism one and fixing mechanism two, thereby solving the problem that the traditional equipment cannot flexibly switch the probes. At the same time, it ensures the stability of the sampling needle during use, avoids looseness, leakage or mismatch caused by loose or unstable connection, effectively improves the sampling efficiency and accuracy, and provides a strong guarantee for obtaining accurate and reliable samples in clinical pharmaceutical experiments.
[0019] 2. The present invention can classify and store samples through the insulation tank and multiple storage tanks of the storage mechanism, which is convenient for management and subsequent experimental use. The cooling tube on the periphery of the storage tank cooperates with the cooler to achieve precise cooling treatment according to the special temperature requirements of different samples, ensuring stable sample quality. This is especially important for some temperature-sensitive samples, which helps to improve the accuracy and reliability of experimental results and provide more valuable data support for clinical pharmaceutical research.
[0020] 3. The present invention realizes multi-angle ultraviolet irradiation disinfection through the coordinated work of the electric slider 1, the electric push rod 3, the tooth plate, the gear and the ultraviolet lamp component, which can effectively kill bacteria, viral microorganisms on the surface of the equipment and the surrounding environment, ensure that the equipment is in a clean and hygienic state before each sampling operation, prevent cross-contamination of samples, create a safe and pollution-free environment for clinical pharmaceutical experiments, effectively guarantee the accuracy and reliability of the experimental results, and also extend the service life of the equipment. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] Figure 1 A perspective view of the present invention;
[0022] Figure 2 It is a schematic diagram of the structure of the protective shell of the present invention;
[0023] Figure 3 It is a structural schematic diagram of the storage mechanism of the present invention;
[0024] Figure 4 It is a schematic diagram of the structure of the sampling needle of the present invention;
[0025] Figure 5 It is a structural schematic diagram of an electric push rod 1 of the present invention;
[0026] Figure 6 It is a structural schematic diagram of the movable block of the present invention;
[0027] Figure 7 It is a structural schematic diagram of the fastening bolt of the present invention;
[0028] Figure 8 It is a structural schematic diagram of the storage tank of the present invention;
[0029] Fig. 9 The schematic diagram of the structure of the sensor of the present invention is
[0030] Fig.10 It is a schematic diagram of the structure of the ultraviolet lamp of the present invention.
[0031] Among them, 1. sampling box; 2. control panel; 3. fixing mechanism 1; 301. protective shell; 302. electric push rod 1; 303. moving block; 304. driving block; 305. movable block; 306. limit rod; 307. limit block; 308. connecting rod; 309. clamping plate; 310. rubber pad; 311. sensor 1; 4. moving assembly; 401. electric slider 2; 402. slide rod; 5. installation assembly; 501. fastening bolt; 502. installation block; 6. fixing mechanism 2; 601. electric push rod 2; 602. Connecting plate; 603, rubber ring; 7, storage mechanism; 701, insulation tank; 702, storage tank; 703, cooler; 704, cooling pipe; 705, delivery pipe; 706, slide plate; 8, preservation component; 801, placement rack; 802, preservation tank; 803, sensor 2; 9, disinfection mechanism; 901, connecting shell; 902, electric push rod 3; 903, movable frame; 904, tooth plate; 905, gear; 906, rotating shaft; 907, ultraviolet lamp; 908, electric slider 1; 10, sampling needle; 11, peristaltic pump. DETAILED DESCRIPTION
[0032] The following will be combined with the drawings in the specification of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0033] Please refer to the attached Figure 1 - Attachment Figure 2 The embodiment of the present invention provides a rapid sampling device for clinical pharmaceutical experiments, including a sampling box 1, a control panel 2 is provided on the front side of the sampling box 1, a fixing mechanism 3 is provided on the side of the sampling box 1 away from the control panel 2, a sampling needle 10 is installed on the side of the fixing mechanism 3 close to the control panel 2, a peristaltic pump 11 is connected to the top of the sampling needle 10 through a pipeline, and a storage mechanism 7 is connected to the end of the peristaltic pump 11 away from the sampling needle 10 through a pipeline, two fixing mechanisms 6 are provided on the bottom side of the interior of the sampling box 1, and a disinfection mechanism 9 is provided inside the sampling box 1;
[0034] In the present invention, the sampling box 1 serves as the overall framework of the equipment, providing a stable installation environment and a reliable protective barrier for the internal components, effectively preventing external interference and ensuring the stable operation of the equipment. The control panel 2 is located on the front side of the sampling box 1, which is convenient for the operator to perform precise function control and parameter setting, while monitoring the equipment operation status in real time and clearly, facilitating timely adjustment to ensure the accuracy and efficiency of the operation. The sampling needle 10 is responsible for collecting clinical pharmaceutical experimental samples, and its top is connected to the peristaltic pump 11 through a pipeline. The peristaltic pump 11 transmits the sample safely and efficiently through the pipeline to the storage mechanism 7 through stable power transmission, thereby ensuring the complete transfer of the sample.
[0035] Please refer to the attached Figure 1 - Attachment Figure 7 The fixing mechanism 13 includes a protective shell 301, which is slidably connected to the inside of the sampling box 1 on a side away from the control panel 2. The top of the protective shell 301 is electrically connected to a sensor 1311. An electric push rod 1302 is installed inside the protective shell 301. The end of the electric push rod 1302 close to the sampling needle 10 is fixedly connected to a moving block 303. The left and right sides of the moving block 303 are fixed with driving blocks 304. The outer periphery of the driving block 304 is slidably connected to a movable block 305. The movable block 305 is fixed with a connecting rod 308 on the side close to the sampling needle 10. The connecting rod 308 The end away from the movable block 305 is connected to a splint 309 through an installation component 5, and a rubber pad 310 is fixed to the side of the splint 309 away from the connecting rod 308. The rubber pad 310 slides on the outer periphery of the sampling needle 10 on the side away from the connecting rod 308. The movable block 305 is internally slidably connected to a limiting rod 306 on the side close to the connecting rod 308. Limiting blocks 307 are installed on both the front and rear sides of the limiting rod 306. The side of the limiting rod 306 away from the movable block 305 is fixed to the inside of the protective shell 301, and a movable component 4 is provided on both the left and right sides of the end of the protective shell 301 away from the sampling needle 10.
[0036] In the present invention, the protective shell 301 is slidably connected inside the sampling box 1, which not only provides protection for the internal components of the fixing mechanism 3, but also drives the entire fixing mechanism 3 to move under the action of the moving component 4, thereby adjusting the position of the sampling needle 10. The sensor 311 on the top can monitor the relevant position information of the protective shell 301 in real time and provide feedback, providing a basis for automatic control of the equipment. The electric push rod 302 is installed in the protective shell 301, and serves as a power source to drive the moving block 303 to move. The driving blocks 304 fixed on the left and right sides of the moving block 303 can drive the movable block 305 slidably connected thereto to move. The movable block 305 slides stably under the restriction of the limit rod 306 and the limit block 307 to ensure the accurate movement direction. It is connected to the splint 309 through the connecting rod 308 and the mounting assembly 5 to realize the clamping or loosening operation of the splint 309 on the sampling needle 10. The rubber pad 310 on the splint 309 contacts the outer periphery of the sampling needle 10, which not only increases the friction to ensure that the sampling needle 10 is firmly fixed, but also prevents the sampling needle 10 from being clamped, thereby ensuring the normal operation of the equipment and the smooth progress of the sampling work.
[0037] Please refer to the attached Figure 8 The storage mechanism 7 includes a heat preservation tank 701, which is installed at the end of the peristaltic pump 11 away from the sampling needle 10 through a pipeline. A plurality of storage tanks 702 evenly distributed in a circle are installed inside the heat preservation tank 701. A cooling pipe 704 is sleeved on the outer periphery of the storage tank 702. One end of the cooling pipe 704 is connected to a cooler 703. A delivery pipe 705 is installed at the bottom of the storage tank 702. A slide plate 706 is fixed on the outer periphery of the delivery pipe 705. The slide plate 706 is slidably connected to the inside of the sampling box 1. The side of the heat preservation tank 701 away from the peristaltic pump 11 is fixed inside the side of the sampling box 1 close to the control panel 2. A preservation component 8 is provided at the end of the delivery pipe 705 away from the storage tank 702.
[0038] In the present invention, the heat preservation tank 701 is connected to the peristaltic pump 11 through a pipeline, and receives the sample collected from the sampling needle 10 and transported by the peristaltic pump 11. The multiple storage tanks 702 evenly distributed in a circle inside the heat preservation tank 701 can classify and store different samples, which is convenient for management and subsequent experimental use. The cooling pipe 704 sleeved on the outer periphery of the storage tank 702 is connected to the cooler 703. After the cooler 703 is started, the coolant can circulate in the cooling pipe 704, and the heat of the sample in the storage tank 702 is taken away through heat exchange, so as to achieve accurate cooling treatment of the sample, meet the special temperature requirements of different samples, and ensure the stability of the sample quality. The delivery tube 705 installed at the bottom of the storage tank 702 is used to transport the sample to the preservation component 8. The slide plate 706 fixed on the outer periphery of the delivery tube 705 is slidably connected to the inside of the sampling box 1. The sliding of the slide plate 706 can accurately control the docking of the delivery tube 705 and the preservation component 8 to ensure that the sample can be smoothly and accurately transferred from the storage tank 702 to the preservation component 8 to avoid sample leakage or loss. At the same time, the insulation tank 701 is fixed inside the sampling box 1 on one side close to the control panel 2. Its stable installation position is conducive to the stable operation of the entire storage mechanism 7, providing reliable protection for the storage and transmission of samples.
[0039] Please refer to the attached Figure 2 The fixing mechanism 6 includes an electric push rod 601, which is fixed inside the sampling box 1. A connecting plate 602 is fixed to one end of the electric push rod 601 close to the sampling needle 10, and a rubber ring 603 is fixed to the side of the connecting plate 602 away from the electric push rod 601.
[0040] In the present invention, the electric push rod 2 601 is used as the power driving component of the fixing mechanism 2 6, which is fixed inside the sampling box 1. When started, it can push the connecting plate 602 connected thereto to move in the direction close to the sampling needle 10. The connecting plate 602 is away from the rubber ring 603 fixed on one side of the electric push rod 2 601. Since rubber has good elasticity and flexibility, under the push of the connecting plate 602, the rubber ring 603 can fit closely to the outer periphery of sample containers of different sizes, generating sufficient friction and clamping force, thereby effectively preventing the sample container from shaking, displacing or tilting instability during the sampling process, effectively ensuring the accuracy and stability of the sampling operation, ensuring the accuracy of each sampling, laying the foundation for obtaining reliable sample data in clinical pharmaceutical experiments, and also avoiding the problem of sample splashing or damage to the sampling needle 10 caused by the shaking of the sample container, thereby improving the safety and reliability of the equipment.
[0041] Please refer to the attached Figure 2 and attached Fig.10The disinfection mechanism 9 includes a connecting shell 901, which is slidably connected to the inside of the sampling box 1, an electric slider 908 is fixed to the side of the connecting shell 901 away from the sampling needle 10, an electric push rod 3 902 is fixed to the inner top side of the connecting shell 901, a movable frame 903 is fixed to the inner top side of the electric push rod 3 902 away from the connecting shell 901, and tooth plates 904 are fixed to the left and right sides of the end of the movable frame 903 close to the sampling needle 10, and rotating shafts 906 are rotatable on the left and right sides of the inside of the connecting shell 901, and gears 905 are fixed to the outer periphery of the rotating shaft 906, and the gears 905 are meshed with the tooth plates 904, and ultraviolet lamps 907 are fixed to the opposite sides of the two rotating shafts 906.
[0042] In the present invention, the connecting shell 901 is slidably connected inside the sampling box 1 to provide an installation basis and protection for other components of the disinfection mechanism 9. An electric slider 908 fixed on the side away from the sampling needle 10 can drive the connecting shell 901 to move inside the sampling box 1, thereby adjusting the disinfection position. The electric push rod 902 fixed on the top side of the connecting shell 901 can push the movable frame 903 to move up and down. The toothed plates 904 fixed on the left and right sides of the movable frame 903 near the sampling needle 10 move with the movable frame 903. The toothed plates 904 are meshed with the gears 905 on the rotating shaft 906 rotating on the left and right sides of the connecting shell 901. When the toothed plates 904 move up and down, the gears 905 rotate accordingly, thereby driving the rotating shaft 906 to rotate. The ultraviolet lamps 907 fixed on the opposite sides of the two rotating shafts 906 rotate with the rotating shafts 906 to achieve multi-angle ultraviolet irradiation disinfection. The ultraviolet rays emitted by the ultraviolet lamps 907 can destroy the DNA structure of microorganisms and effectively kill bacteria and viral microorganisms, ensuring the cleanliness of the equipment surface and the surrounding environment, providing a safe and pollution-free environment for the next sampling operation, preventing cross-contamination of samples, and ensuring the accuracy and reliability of clinical pharmaceutical experimental results.
[0043] Please refer to the attached Figure 7 The mounting assembly 5 includes a fastening bolt 501, which is threadedly connected to one end of the connecting rod 308 away from the movable block 305, and a mounting block 502 is fixed to one side of the clamping plate 309 close to the connecting rod 308, and the outer periphery of the fastening bolt 501 is threadedly connected to the inside of the mounting block 502.
[0044] In the present invention, the fastening bolt 501 is threadedly connected to one end of the connecting rod 308 and the inside of the mounting block 502 of the clamping plate 309, playing a key fastening role. It can firmly connect the clamping plate 309 to the connecting rod 308, ensuring that when the sampling needle 10 is fixed, the clamping plate 309 will not be easily loosened or shifted, so that the sampling needle 10 is reliably clamped, thereby ensuring the stability of the sampling needle 10 during the sampling process, providing strong support for accurate sampling, and ensuring the normal operation of the equipment and the smooth progress of the experiment.
[0045] Please refer to the attached Figure 2 The two moving components 4 each include an electric slider 401 , which are respectively fixedly connected to the left and right sides of the protective shell 301 , and slide bars 402 are fixedly provided on the left and right sides of the interior of the sampling box 1 , and the two electric sliders 401 are respectively slidably connected to the outer periphery of the two slide bars 402 .
[0046] In the present invention, the electric slider 2 401 is fixed on both sides of the protective shell 301 and is slidably connected to the slide bar 402 in the sampling box 1. When the electric slider 2 401 is working, it can drive the protective shell 301 to move smoothly along the slide bar 402, and then accurately adjust the position of the fixing mechanism 1 3 and the sampling needle 10, so as to facilitate efficient and accurate sampling operations at different positions in the sampling box 1, thereby improving the flexibility and practicality of the equipment.
[0047] Please refer to the attached Figure 8 - Attachment Fig. 9 The preservation component 8 includes a preservation tank 802, which is arranged at one end of the conveying pipe 705 away from the storage tank 702, and a sensor 2 803 is arranged on the side of the preservation tank 802 away from the slide 706. A placement rack 801 is slid inside the side of the sampling box 1 close to the control panel 2, and the sensor 2 803 is installed inside the placement rack 801.
[0048] In the present invention, the storage tank 802 is located at one end of the delivery tube 705, and is used to receive and safely store the sample delivered from the storage tank 702, ensuring the integrity of the sample before subsequent experiments. The sensor 2 803 on the side away from the slide 706 is installed in the sliding placement rack 801, which can detect the liquid level or weight information of the sample in the storage tank 802, and transmit the signal to the control panel 2, so that the operator can know the storage status in time, so as to replace the storage tank 802 or perform the next processing operation, ensure the orderly sample storage process, and avoid overflow or improper storage problems.
[0049] Working principle: Before sampling, align the mounting block 502 of the clamp plate 309 with one end of the connecting rod 308, then pass the fastening bolt 501 through the connecting rod 308 and screw it into the threaded hole of the mounting block 502, then start the electric push rod 1 302, the electric push rod 1 302 pushes the moving block 303 fixedly connected to it to move in the protective shell 301, and the driving blocks 304 on the left and right sides of the moving block 303 move with the moving block 303, and the movable block 303 connected to the outer periphery of the driving block 304 slides. The movable block 305 slides on the limiting rod 306, and the connecting rod 308 fixed on the side of the movable block 305 close to the sampling needle 10 moves synchronously with the movable block 305, thereby driving the clamping plate 309 to move, thereby fixing the sampling needle 10. The electric sliders 401 on the left and right sides of the protective shell 301 can slide on the sliding rods 402 fixed on the left and right sides inside the sampling box 1. The electric sliders 401 drive the protective shell 301 to move as a whole, and further drive the sampling needle 10 to move, thereby facilitating the sampling operation at different positions in the sampling box 1.
[0050] When the sample container needs to be fixed, the electric push rod 601 is started, and the electric push rod 601 pushes the connecting plate 602 to move toward the sample container. The rubber ring 603 fixed on the side of the connecting plate 602 away from the electric push rod 601 contacts the outer periphery of the sample container. The rubber ring 603 has a certain elasticity and can fit tightly to sample containers of different sizes to prevent the sample containers from shaking or shifting during the sampling process, thereby ensuring the accuracy of sampling. Then the sampling needle 10 enters the container to start sampling. After sampling, the liquid will be diverted into each storage tank 702 through the peristaltic pump 11.
[0051] After the liquid enters the storage tank 702, the cooler 703 can be started. The cooler 703 allows the coolant to circulate in the cooling pipe 704, and takes away the heat of the sample in the storage tank 702 through heat exchange, thereby achieving a cooling treatment of the sample to meet the temperature requirements of different samples. The delivery pipe 705 installed at the bottom of the storage tank 702 is used to transport the sample to the preservation component 8. The slide plate 706 fixed on the outer periphery of the delivery pipe 705 is slidably connected to the inside of the sampling box 1, and is used to control the movement of the delivery pipe 705 and the docking with the preservation tank 802, ensuring that the sample can be smoothly transported from the storage tank 702 to the preservation tank 802;
[0052] When sensor 2 803 detects that the preservation tank 802 is full of samples or reaches the preset preservation conditions, it will transmit a signal to the control panel 2, prompting the operator to perform corresponding operations, such as replacing the preservation tank 802 or performing further processing on the preserved samples, thereby ensuring the orderly progress of the sample preservation process and avoiding sample overflow or improper preservation.
[0053] After the sampling is completed, the disinfection operation begins, the ultraviolet lamp 907 is controlled to start, emit ultraviolet rays, and the electric push rod 3 902 is started. The electric push rod 3 902 pushes the movable frame 903 to move up and down inside the connecting shell 901, and the toothed plates 904 fixed on the left and right sides of the movable frame 903 near the sampling needle 10 move with the movable frame 903. The toothed plates 904 are engaged with the gears 905 on the rotating shaft 906 rotatably installed on the left and right sides of the connecting shell 901. When the toothed plates 904 move up and down, the gears 905 rotate accordingly, thereby driving the rotating shaft 906 to rotate. The ultraviolet lamps 907 fixed on the opposite sides of the two rotating shafts 906 rotate with the rotating shaft 906 to achieve multi-angle ultraviolet irradiation disinfection. The ultraviolet rays emitted by the ultraviolet lamps 907 can destroy the DNA structure of microorganisms, thereby achieving the purpose of sterilization and disinfection, ensuring the cleanliness of the equipment surface and the surrounding environment, and providing safety protection for the next sampling operation.
[0054] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A rapid sampling device for clinical pharmaceutical experiments, comprising a sampling box (1), characterized in that: The sampling box (1) is provided with a control panel (2) on the front side, a fixing mechanism (3) is provided on the side of the interior of the sampling box (1) away from the control panel (2), a sampling needle (10) is installed on the side of the fixing mechanism (3) close to the control panel (2), the top of the sampling needle (10) is connected to a peristaltic pump (11) via a pipeline, the end of the peristaltic pump (11) away from the sampling needle (10) is connected to a storage mechanism (7) via a pipeline, two fixing mechanisms (6) are provided on the bottom side of the interior of the sampling box (1), and a disinfection mechanism (9) is provided inside the sampling box (1); The fixing mechanism (3) comprises a protective shell (301), the protective shell (301) is slidably connected to the inside of a side of the sampling box (1) away from the control panel (2), the top of the protective shell (301) is electrically connected to a sensor (311), an electric push rod (302) is installed inside the protective shell (301), and a moving block (303) is fixedly connected to one end of the electric push rod (302) close to the sampling needle (10), and driving blocks (304) are fixed on the left and right sides of the moving block (303), and the outer periphery of the driving block (304) is slidably connected to the sampling needle (10). A movable block (305) is connected, a connecting rod (308) is fixed on a side of the movable block (305) close to the sampling needle (10), an end of the connecting rod (308) away from the movable block (305) is connected to a clamping plate (309) through a mounting assembly (5), an inner sliding connection of the movable block (305) close to the connecting rod (308) is connected to a limit rod (306), and limit blocks (307) are installed on both the front and rear sides of the limit rod (306), and a movable assembly (4) is provided on both the left and right sides of the end of the protective shell (301) away from the sampling needle (10).
2. A rapid sampling device for clinical pharmaceutical experiments according to claim 1, characterized in that: The storage mechanism (7) comprises a heat preservation tank (701), wherein the heat preservation tank (701) is installed at one end of the peristaltic pump (11) away from the sampling needle (10) through a pipeline, and a plurality of storage tanks (702) evenly distributed in a circle are installed inside the heat preservation tank (701), and a cooling pipe (704) is sleeved on the outer circumference of the storage tank (702), and one end of the cooling pipe (704) is connected to a cooler (703), and a delivery pipe (705) is installed at the bottom of the storage tank (702), and a slide plate (706) is fixed on the outer circumference of the delivery pipe (705), and a preservation component (8) is provided at one end of the delivery pipe (705) away from the storage tank (702).
3. A rapid sampling device for clinical pharmaceutical experiments according to claim 1, characterized in that: The second fixing mechanism (6) comprises a second electric push rod (601), which is fixed inside the sampling box (1). A connecting plate (602) is fixed to one end of the second electric push rod (601) close to the sampling needle (10), and a rubber ring (603) is fixed to the side of the connecting plate (602) away from the second electric push rod (601).
4. A rapid sampling device for clinical pharmaceutical experiments according to claim 1, characterized in that: The disinfection mechanism (9) comprises a connecting shell (901), wherein the connecting shell (901) is slidably connected to the interior of the sampling box (1), an electric slider (908) is fixed to the side of the connecting shell (901) away from the sampling needle (10), an electric push rod (902) is fixed to the internal top side of the connecting shell (901), a movable frame (903) is fixed to the internal top side of the electric push rod (902) away from the connecting shell (901), tooth plates (904) are fixed to the left and right sides of one end of the movable frame (903) close to the sampling needle (10), a rotating shaft (906) is rotatably provided on the left and right sides of the interior of the connecting shell (901), a gear (905) is fixed to the outer periphery of the rotating shaft (906), the gear (905) is meshed with the tooth plate (904), and an ultraviolet lamp (907) is fixed to the opposite side of the two rotating shafts (906).
5. A rapid sampling device for clinical pharmaceutical experiments according to claim 1, characterized in that: The mounting assembly (5) comprises a fastening bolt (501), wherein the fastening bolt (501) is threadedly connected to an end of the connecting rod (308) away from the movable block (305), a mounting block (502) is fixed to a side of the clamping plate (309) close to the connecting rod (308), and the outer periphery of the fastening bolt (501) is threadedly connected to the inside of the mounting block (502).
6. A rapid sampling device for clinical pharmaceutical experiments according to claim 1, characterized in that: The two moving components (4) each include an electric slider (401), and the two electric sliders (401) are respectively fixedly connected to the left and right sides of the protective shell (301). Slide rods (402) are fixed on the left and right sides of the interior of the sampling box (1), and the two electric sliders (401) are respectively slidably connected to the outer periphery of the two slide rods (402).
7. A rapid sampling device for clinical pharmaceutical experiments according to claim 2, characterized in that: The preservation component (8) includes a preservation tank (802), and the preservation tank (802) is arranged at one end of the conveying pipe (705) away from the storage tank (702), and a second sensor (803) is arranged on the side of the preservation tank (802) away from the slide plate (706). A placement rack (801) is slidably provided inside the side of the sampling box (1) close to the control panel (2), and the second sensor (803) is installed inside the placement rack (801).
8. A rapid sampling device for clinical pharmaceutical experiments according to claim 1, characterized in that: A rubber pad (310) is fixed to the side of the clamping plate (309) away from the connecting rod (308), and the rubber pad (310) slides on the outer periphery of the sampling needle (10) on the side away from the connecting rod (308).
9. A rapid sampling device for clinical pharmaceutical experiments according to claim 2, characterized in that: The slide plate (706) is slidably connected to the interior of the sampling box (1), and the side of the heat preservation tank (701) away from the peristaltic pump (11) is fixed inside the side of the sampling box (1) close to the control panel (2).
10. A rapid sampling device for clinical pharmaceutical experiments according to claim 1, characterized in that: The side of the limiting rod (306) away from the movable block (305) is fixed inside the protective shell (301).