Traditional Chinese medicine spray for treating skin diseases and preparation method thereof

Abstract

The invention relates to the technical field of traditional Chinese medicines for treating skin diseases, and aims to solve the technical problems that the existing adopted treatment means mainly adopts hormone medicines and some skin care product ointments and traditional Chinese medicine prescriptions which have the defects of long treatment time, slow effect taking, high cost, pain and economic burden brought to patients and incapability of achieving a rapid treatment effect. The invention discloses a traditional Chinese medicine spray for treating skin diseases. The traditional Chinese medicine spray is prepared from the following components in parts by weight: 5-10 parts of ipomoea cairica, 4-9 parts of rhizoma dioscoreae nipponicae, 6-11 parts of dragon skin, 3-9 parts of bulbophyllum, 4-11 parts of solanum nigrum and 4-7 parts of ginseng. The preparation method of the traditional Chinese medicine spray comprises the steps of raw material preparation, cleaning and drying, crushing and mixing, soaking and extracting, filtering and filling and the like, the traditional Chinese medicine spray has the effects of clearing away heat and toxic materials, dissipating blood stasis and diminishing swelling, sterilizing and diminishing inflammation and relieving pain and itching, all the traditional Chinese medicinal materials are mutually matched and can play a synergistic role to jointly treat skin diseases, the time is short, and the effect is fast.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicines, and in particular to a traditional Chinese medicine spray for treating skin diseases and a preparation method thereof. Background Art

[0002] Skin diseases are diseases of the skin, which is composed of the epidermis, dermis and subcutaneous tissue and covers the body surface. They are caused by various physical and chemical factors, pathogen infection, endocrine metabolic factors, immunogenicity and degenerative changes, which cause disorders in the skin's barrier, absorption, sensation, secretion and excretion, temperature regulation, material metabolism, immunity and other functions, as well as fungi, bacteria, viruses and other microorganisms, and produce various symptoms on the skin surface, causing the skin to feel different degrees of swelling, pain, distension and itching, causing great pain to patients and affecting their normal life and work;

[0003] Traditional Western medicine treatments mostly use hormone drugs, antibiotics or immunosuppressants. Although they have significant short-term effects, long-term use may bring side effects, such as skin atrophy, pigmentation, dependent dermatitis, etc. Therefore, more and more patients and doctors are beginning to seek safer and gentler treatments.

[0004] Traditional Chinese medicine has a long history and rich experience in treating skin diseases. With its natural, mild and few side effects, traditional Chinese medicine has gradually become an important choice for the treatment of skin diseases. Traditional Chinese medicine can fundamentally improve the symptoms of skin diseases through multiple effects such as regulating the internal environment of the human body, enhancing immunity, anti-inflammatory, antipruritic, and skin repair, and is not easy to develop drug resistance. In recent years, traditional Chinese medicine sprays, as a new type of external preparation, have attracted widespread attention due to their convenience, rapid drug absorption, and significant efficacy. Traditional Chinese medicine sprays can act directly on the affected area, avoiding the first-pass effect of oral drugs and improving the bioavailability of drugs. In addition, traditional Chinese medicine sprays usually use natural plant extracts, which reduces the irritation of chemical synthetic ingredients to the skin and is suitable for long-term use.

[0005] However, there are still some problems with the traditional Chinese medicine spray in the prior art. First, the composition of some traditional Chinese medicine sprays is not reasonable, resulting in limited efficacy or a narrow scope of application; second, the preparation process is complicated and it is difficult to achieve large-scale production; therefore, the development of a traditional Chinese medicine spray with reasonable composition, simple preparation process and significant efficacy has important clinical significance and market value.

[0006] It is under this background that the present invention provides a new type of Chinese medicine spray for treating skin diseases by in-depth research on traditional Chinese medicine formulas and combining modern preparation technology. Summary of the invention

[0007] The technical problem to be solved by the present invention is to overcome the defects of the above-mentioned technology and provide a Chinese medicine spray for treating skin diseases and a preparation method thereof.

[0008] To solve the above technical problems, the technical solution provided by the present invention is a traditional Chinese medicine spray for treating skin diseases, which is composed of the following components: five-clawed golden dragon, dactylorhizon, dragon clothes, dragon spit pearl, nightshade, and ginseng.

[0009] Furthermore, the Chinese medicine spray is composed of the following components in parts by weight: 5-10 parts of Ipomoea aurea, 4-9 parts of Rhizoma Dioscoreae, 6-11 parts of Rhizoma Dioscoreae, 3-9 parts of Glechoma longituba, 4-11 parts of Solanum nigrum, and 4-7 parts of Ginseng.

[0010] Furthermore, the Chinese medicine spray is composed of the following components in parts by weight: 6 parts of Ipomoea aurea, 6 parts of Rhizoma Dioscoreae ... and 6 parts of Rhizoma Dioscoreae.

[0011] Furthermore, the Chinese medicine spray is composed of the following components in parts by weight: 5 parts of Ipomoea aurea, 4 parts of Rhizoma Dioscoreae, 6 parts of Rhizoma Dioscoreae, 3 parts of Glechoma longituba, 4 parts of Solanum nigrum, and 4 parts of Ginseng.

[0012] Furthermore, the Chinese medicine spray is composed of the following components in parts by weight: 10 parts of Ipomoea aurea, 9 parts of Rhizoma Dioscoreae, 11 parts of Rhizoma Dioscoreae, 9 parts of Rhizoma Dioscoreae, 11 parts of Rhizoma Dioscoreae, and 7 parts of Rhizoma Ginseng.

[0013] Furthermore, the preparation method of the traditional Chinese medicine spray comprises the following steps:

[0014] Step 1) Raw material preparation: Select the above-mentioned raw materials without mildew or insect infestation, carefully select them respectively, and remove impurities;

[0015] Step 2) Cleaning and drying: The selected raw materials are thoroughly cleaned with purified water, and then placed in a well-ventilated and temperature-appropriate environment to dry naturally or use low-temperature drying equipment to dry;

[0016] Step 3) Crushing and mixing: Crushing the dried raw materials separately and passing them through a 80-120 mesh sieve. Then, accurately weighing the raw materials according to the above weight ratio and mixing them evenly;

[0017] Step 4) Soaking and extraction: Place the mixed raw materials in a sealed container and add 50%-70% by volume of 60% liquor to ensure that the medicinal materials are completely soaked. The soaking time is controlled to be 15-30 days, and stir regularly during this period to promote the dissolution of the active ingredients;

[0018] Step 5) Filtration and filling: After the soaking is completed, filter out the drug residue through multiple layers of gauze or a fine filter to obtain the extract, inject it into a spray bottle through a sterile filling device, and seal it for storage.

[0019] The sources of raw materials used in the present invention are as follows:

[0020] Five-clawed Golden Dragon: Five-clawed Golden Dragon has the effects of dispelling wind and dampness, setting bones and tendons, dispersing blood stasis and reducing swelling. The ingredients contained in it, such as quercetin-7,4'-dimethyl ether and its sulfate, have significant effects on treating skin diseases such as wet and rotten skin, burns caused by water or fire, and nameless swelling. In the present invention, Five-clawed Golden Dragon, as one of the main ingredients, can play the role of dispelling wind and dampness, reducing swelling and relieving pain.

[0021] Rhizoma Dioscoreae: Rhizoma Dioscoreae has the effects of dispelling wind and dampness, relaxing muscles and tendons, reducing swelling and relieving pain. It tastes bitter and pungent, is neutral in nature, and enters the liver and lung meridians. It has significant therapeutic effects on treating rheumatic arthralgia, falls and injuries, and the like. In the present invention, Rhizoma Dioscoreae can cooperate with Polygonum multiflorum to enhance the effects of dispelling wind and dampness, reducing swelling and relieving pain.

[0022] Longyi (snake skin): Longyi has the effects of dispelling wind, calming the nerves, detoxifying, and removing cataracts. It is good at dispelling wind, opening the orifices, calming the nerves, and can remove wind from the internal organs and orifices. It has a unique therapeutic effect on treating skin diseases such as vitiligo, scabies, acne, eczema, etc. In the present invention, Longyi can play the role of detoxification and antipruritic, and help relieve symptoms such as itching, redness and swelling caused by skin diseases.

[0023] Clerodendrum thomsoniae: Clerodendrum thomsoniae has the effects of clearing away heat, cooling blood, reducing swelling and detoxifying. In clinical practice, Clerodendrum thomsoniae is often used to treat sore throat, carbuncle, furuncle, snake and insect bites, and burns. In the present invention, Clerodendrum thomsoniae can play the role of clearing away heat and detoxifying, reducing swelling and relieving pain, and helps to accelerate the recovery of skin diseases.

[0024] Solanum nigrum: Solanum nigrum has the effects of promoting blood circulation and reducing swelling, relieving fever and pain, and antibacterial. The large amount of alkaloids it contains can act on the nervous system, inhibit nerve activity, reduce pain, and play an analgesic role. At the same time, Solanum nigrum decoction has a certain antibacterial effect on a variety of pathogenic cocci and bacilli. In the present invention, Solanum nigrum can play an antibacterial and anti-inflammatory role, which helps to prevent infections caused by skin diseases.

[0025] Ginseng: Ginseng has multiple functions such as improving immunity, providing energy, improving cognitive function, reducing stress response, and anti-oxidation. In the present invention, ginseng is used as an auxiliary ingredient to enhance the body's immunity and promote the recovery of skin diseases. At the same time, the antioxidant effect of ginseng helps to reduce oxidative damage and protect skin cells from damage.

[0026] The advantages of the present invention compared with the prior art are:

[0027] The Chinese medicine spray for treating skin diseases provided by the present invention is a pure Chinese medicine preparation, which is for external use and has no toxic side effects. The Chinese medicine spray has the effects of clearing away heat and detoxifying, dispersing blood stasis and reducing swelling, sterilizing and reducing inflammation, relieving pain and relieving itching. The Chinese medicinal materials of each component cooperate with each other to play a synergistic role and jointly treat skin diseases in a short time and with quick effects. Clinical experiments have shown that the Chinese medicine spray has a particularly good effect on treating eczema dermatitis, herpes zoster, mosquito bites, and tendon bags, and has a good effect on acne, blisters on the mouth, toothache, and mild burns, and has high safety, so it is worthy of promotion and application. DETAILED DESCRIPTION

[0028] The following is a further detailed description of a Chinese medicine spray for treating skin diseases and a preparation method of the present invention in conjunction with embodiments.

[0029] Embodiment 1:

[0030] Take 5 parts of five-clawed golden dragon, 4 parts of dactylorhizon, 6 parts of dragon clothes, 3 parts of dragon's vomiting pearl, 4 parts of nightshade, and 4 parts of ginseng, wash and dry each kind of medicinal materials separately, soak them in 60-degree white wine, soak for three weeks, and filter to get the traditional Chinese medicine spray.

[0031] Usage: Spray the obtained Chinese medicine spray directly on the patient's diseased skin, and scratch the painful and itchy skin lightly at the same time, and scratch the painful and itchy epidermis so that the medicine can penetrate into the inner layer of the skin smoothly. With this unique way of administration, the medicine can quickly reach the lesion and directly act on the bacteria. In a very short time, about 10 minutes, it can effectively suppress the symptoms of pain and itching, and bring immediate relief to the patient. Moreover, within 12 hours, the diseased area can show scab phenomenon, fully demonstrating its excellent therapeutic effect.

[0032] The entire treatment process is convenient and efficient. Patients do not need to take a large amount of complicated Chinese medicine prescriptions orally. It also avoids the many disadvantages that may be caused by the large-scale use of hormones and antibiotics. It greatly reduces the pain that patients suffer during treatment. At the same time, it significantly reduces the economic burden on patients and effectively curbs the current bad trend of hormone and antibiotic abuse.

[0033] Embodiment 2:

[0034] Take 6 parts of Ipomoea aurea, 6 parts of Rhizoma Dioscoreae ... and 6 parts of Rhizoma Dioscoreae, and prepare a Chinese medicine spray according to the above method.

[0035] Usage: Spray the obtained Chinese medicine spray directly on the patient's diseased skin, and scratch the painful and itchy skin lightly at the same time, and scratch the painful and itchy epidermis so that the medicine can penetrate into the inner layer of the skin smoothly. With this unique way of administration, the medicine can quickly reach the lesion and directly act on the bacteria. In a very short time, about 10 minutes, it can effectively suppress the symptoms of pain and itching, and bring immediate relief to the patient. Moreover, within 12 hours, the diseased area can show scab phenomenon, fully demonstrating its excellent therapeutic effect.

[0036] The entire treatment process is convenient and efficient. Patients do not need to take a large amount of complicated Chinese medicine prescriptions orally. It also avoids the many disadvantages that may be caused by the large-scale use of hormones and antibiotics. It greatly reduces the pain that patients suffer during treatment. At the same time, it significantly reduces the economic burden on patients and effectively curbs the current bad trend of hormone and antibiotic abuse.

[0037] Embodiment 3:

[0038] Take 10 parts of Ipomoea aurea, 9 parts of Rhizoma Dioscoreae, 11 parts of Rhizoma Dioscoreae, 9 parts of Rhizoma Dioscoreae, 11 parts of Rhizoma Dioscoreae, and 7 parts of Radix Ginseng, and prepare a Chinese medicine spray according to the above method.

[0039] Usage: Spray the obtained Chinese medicine spray directly on the patient's diseased skin, and scratch the painful and itchy skin lightly at the same time, and scratch the painful and itchy epidermis so that the medicine can penetrate into the inner layer of the skin smoothly. With this unique way of administration, the medicine can quickly reach the lesion and directly act on the bacteria. In a very short time, about 10 minutes, it can effectively suppress the symptoms of pain and itching, and bring immediate relief to the patient. Moreover, within 12 hours, the diseased area can show scab phenomenon, fully demonstrating its excellent therapeutic effect.

[0040] The entire treatment process is convenient and efficient. Patients do not need to take a large amount of complicated Chinese medicine prescriptions orally. It also avoids the many disadvantages that may be caused by the large-scale use of hormones and antibiotics. It greatly reduces the pain that patients suffer during treatment. At the same time, it significantly reduces the economic burden on patients and effectively curbs the current bad trend of hormone and antibiotic abuse.

[0041] Example 4 Toxicity Test

[0042] Thirty adult Kunming mice, half male and half female, without disease or abnormal behavior, were randomly divided into three groups, 10 mice in each group, namely the control group, the experimental group, and the high-dose group;

[0043] The above three groups were fed normally, among which the control group was gavaged with 25 ml of normal saline three times a day on the basis of normal feeding, the experimental group was gavaged with 5 ml of the spray of Example 1 once a day, and the high-dose group was gavaged with the high-dose spray of Example 1 three times a day, totaling 15 ml;

[0044] The mice were gavaged for 7 consecutive days and their conditions were observed every day. The activities and diet of mice in the control and experimental groups were normal. Two mice in the high-dose group had diarrhea and vomiting on the fourth day, and one mouse died on the seventh day. After 7 days, mice in the experimental group were randomly selected for autopsy, and no abnormalities were found in their organs.

[0045] Example 5 Typical Cases

[0046] 1) Li, male, 68 years old

[0047] Condition description: The patient started to suffer from eczema dermatitis more than 10 years ago, and the condition recurred, with unbearable itching, which seriously affected the quality of life. During this period, he used a variety of hormone ointments and went to a large hospital in the provincial capital to treat skin diseases, but no significant treatment effect was achieved.

[0048] Description after recovery: After using this Chinese medicine spray, the patient's itching symptoms were significantly relieved in about 10 minutes. After 12 hours of treatment, the affected area with broken skin began to scab and heal. For the affected area with unbroken skin around it, although there was repeated itching in the early stage, after continuous use according to the doctor's advice, the itching symptoms were effectively controlled, and the affected area gradually scabbed and recovered.

[0049] 2) Gong Moumou, male, 91 years old

[0050] Condition description: One year ago, the patient began to experience symptoms of eczema dermatitis on his back. He used a variety of ointments for treatment, but the results were not ideal and the condition continued to worsen.

[0051] Description after recovery: After using this Chinese medicine spray, the patient's eczema dermatitis symptoms gradually subsided, and the skin of the affected area gradually returned to normal. After a period of consolidation treatment, the patient's eczema dermatitis was completely cured, and there has been no recurrence so far.

[0052] 3) Xu, female, 61 years old

[0053] Condition description: The patient suffers from long-term unbearable itching on the calf, and frequent scratching leads to skin damage.

[0054] Description after recovery: After using this Chinese medicine spray, the patient's itching symptoms were quickly controlled, and the damaged skin began to scab and heal after spraying. After a period of continuous treatment, the patient's calf skin was completely restored to health and the itching symptoms disappeared.

[0055] 4) Zhang, male, 58 years old

[0056] Condition description: The patient suffers from eczema dermatitis on the back, with unbearable itching and frequent scratching leading to skin damage.

[0057] Description after recovery: After using this Chinese medicine spray, the patient's itching symptoms were significantly relieved, and the damaged skin gradually scabbed and healed. After continuous treatment, the patient's back eczema dermatitis symptoms completely disappeared, and the skin returned to a healthy state.

[0058] 5) Li, male, 63 years old

[0059] Condition description: The patient suffers from shingles in the front chest ribs, with unbearable pain and itching, like being pricked by needles, which seriously affects daily life.

[0060] Description after recovery: After using this Chinese medicine spray 2-3 times a day, the patient's shingles symptoms were quickly controlled. After 3 days of continuous treatment, the patient's pain and itching symptoms completely disappeared, and shingles were completely cured. After recovery, the skin recovered well without leaving any scars or pigmentation.

[0061] 6) Yu, male, 36 years old

[0062] Condition description: The patient suffers from eczema on the front of the waist, with unbearable itching and recurring symptoms.

[0063] Description after recovery: After using this Chinese medicine spray, the patient's eczema symptoms gradually subsided and the itching was controlled. After a period of consolidation treatment, the patient's eczema was completely cured and has not recurred so far. The skin has returned to a healthy state and the quality of life has been significantly improved.

[0064] 7) Li, male, 14 years old

[0065] Condition description: The patient suffers from acne on his face and frequent pimples, which seriously affect his appearance and self-confidence.

[0066] Description after recovery: Apply the medicine on the face 2-3 times a day, and the acne will disappear after 3-5 days. On the first day after using this Chinese medicine spray, the acne on the skin surface increases. Under the action of the medicine, the pathogens in the subcutaneous tissue are invaded and infected by pathogens and gathered in the epidermis, which is manifested as an increase in the pimples on the epidermis; on the second and third days after taking the medicine, the pathogens and impurities are gradually eliminated as white objects under the action of the medicine; after the fourth day, the skin surface begins to repair, making the face white and smooth, smooth and scar-free, achieving the effect of removing acne and nourishing the skin.

[0067] The present invention and its implementation methods are described above, and such description is not restrictive. In short, if ordinary technicians in the field are inspired by it, without departing from the purpose of the invention, they can design structures and embodiments similar to the technical solution without creativity, which should all fall within the protection scope of the present invention.

Claims

1. A Chinese medicine spray for treating skin diseases, characterized in that: The Chinese medicine spray is composed of the following components: five-clawed golden dragon, dactylorhizon, dragon clothes, dragon's mouth, nightshade, and ginseng.

2. The Chinese medicine spray according to claim 1, characterized in that: The Chinese medicine spray is composed of the following components in parts by weight: 5-10 parts of Ipomoea aurea, 4-9 parts of Rhizoma Dioscoreae, 6-11 parts of Rhizoma Dioscoreae, 3-9 parts of Glechoma longituba, 4-11 parts of Solanum nigrum, and 4-7 parts of Ginseng.

3. The Chinese medicine spray according to claim 1 or 2, characterized in that: The Chinese medicine spray is composed of the following components in parts by weight: 6 parts of Ipomoea aurea, 6 parts of Rhizoma Dioscoreae ... and 6 parts of Rhizoma Dioscoreae.

4. The Chinese medicine spray according to claim 1 or 2, characterized in that: The Chinese medicine spray is composed of the following components in parts by weight: 5 parts of Ipomoea aurea, 4 parts of Rhizoma Dioscoreae, 6 parts of Rhizoma Dioscoreae, 3 parts of Glechoma longituba, 4 parts of Solanum nigrum, and 4 parts of Ginseng.

5. The Chinese medicine spray according to claim 1 or 2, characterized in that: The Chinese medicine spray is composed of the following components in parts by weight: 10 parts of Ipomoea aurea, 9 parts of Rhizoma Dioscoreae, 11 parts of Rhizoma Dioscoreae, 9 parts of Rhizoma Dioscoreae, 11 parts of Rhizoma Dioscoreae, and 7 parts of Rhizoma Ginseng.

6. The method for preparing the Chinese medicine spray according to any one of claims 1 to 5, characterized in that: The following steps are involved: Step 1) Raw material preparation: Select the above-mentioned raw materials without mildew or insect infestation, carefully select them respectively, and remove impurities; Step 2) Cleaning and drying: The selected raw materials are thoroughly cleaned with purified water, and then placed in a well-ventilated and temperature-appropriate environment to dry naturally or use low-temperature drying equipment to dry; Step 3) Crushing and mixing: crush the dried raw materials separately and pass them through a 80-120 mesh sieve. Then, accurately weigh the raw materials according to the above weight ratio and mix them evenly; Step 4) Soaking and extraction: Place the mixed raw materials in a sealed container and add 50%-70% by volume of 60% liquor to ensure that the herbs are completely soaked. The soaking time is controlled to be 15-30 days, and stir regularly during this period to promote the dissolution of the active ingredients; Step 5) Filtration and filling: After the soaking is completed, filter out the drug residue through multiple layers of gauze or a fine filter to obtain the extract, inject it into a spray bottle through a sterile filling device, and seal it for storage.