Movement module, modularized biochemical analyzer and assembling method of modularized biochemical analyzer

Abstract

The invention relates to the technical field of biochemical detection, and discloses a machine core module, a modularized biochemical analyzer and an assembling method thereof.The machine core module comprises a reaction disc, the reaction disc is arranged in the middle of a machine core base, and a plurality of reaction cups are annularly arranged in the reaction disc; the output end of the reaction disc driving module is connected with the reaction disc; the photoelectric colorimetric module is arranged on the outer side of the reaction disc; the sample filling mechanism is used for filling and cleaning a sample; a reagent filling mechanism; a stirring and uniform mixing mechanism; the cleaning mechanism is used for performing liquid injection and drainage cleaning on the reaction cup; a liquid path module; the sample filling mechanism, the reagent filling mechanism, the stirring and mixing mechanism and the cleaning mechanism are sequentially arranged in the rotating direction of the reaction disc, an emergency treatment cylinder position is further arranged on the machine core base, an emergency treatment test tube rack is inserted into the emergency treatment cylinder position, and a plurality of insertion holes matched with test tubes are annularly formed in the emergency treatment test tube rack.

Description

Technical Field

[0001] The present invention relates to the technical field of biochemical detection, and in particular to a core module, a modular biochemical analyzer and an assembly method thereof. Background Art

[0002] A biochemical analyzer, also often referred to as a biochemical instrument, is an instrument that uses the principle of photoelectric colorimetry to measure a specific chemical component in body fluids. Due to its fast measurement speed, high accuracy, and small consumption of reagents, it has now been widely used in hospitals at all levels. When used in combination, it can greatly improve the efficiency and benefits of routine biochemical tests. An automatic biochemical analyzer is an instrument that mimics manual operations to complete some or all of the steps in biochemical analysis, such as sampling, adding reagents, removing interfering substances, mixing, incubating, colorimetry, result calculation, printing reports, and cleaning. Existing biochemical analyzers usually independently have a sample disk, a reagent disk, and a reaction disk, and are equipped with multiple sampling needles for operation. Such equipment is large in size and complex in structure, and it is difficult to maintain the equipment during actual use. The operation of a biochemical analyzer requires the coordinated work of multiple mechanisms. The complex structure of traditional equipment directly leads to the need to send the whole machine for repair when small components are damaged, affecting the use of the equipment. Summary of the Invention

[0003] The technical problem to be solved by the present invention is to overcome the deficiencies of the prior art and provide a core module, a modular biochemical analyzer and an assembly method thereof, which are convenient for realizing the modular assembly of the whole biochemical analyzer.

[0004] The technical solution of the present invention is as follows: On the one hand, the present invention discloses a movement module, which includes a movement base; a reaction disc, the reaction disc is arranged in the middle of the movement base, and a plurality of reaction cups are arranged in a ring in the reaction disc; a reaction disc drive module, the output end of the reaction disc drive module is connected to the reaction disc for driving the reaction disc to rotate; a photoelectric colorimetric module, arranged outside the reaction cup for performing photoelectric colorimetry on the solution in the reaction cup; a sample adding mechanism for realizing the adding and cleaning of samples; a reagent adding mechanism, including a first reagent adding unit and a second reagent adding unit, for realizing the adding and cleaning of reagents; a stirring and mixing mechanism, including a first stirring and mixing unit and a second stirring and mixing unit, for realizing the stirring and mixing of the sample solution and the reagent solution in the reaction cup; a cleaning mechanism for performing injection and drainage cleaning on the reaction cup; a liquid path module, the liquid path module is respectively connected to the sample adding mechanism, the reagent adding mechanism, the stirring and mixing mechanism and the cleaning mechanism for liquid path transportation in biochemical reactions; the sample adding mechanism, the reagent adding mechanism, the stirring and mixing mechanism and the cleaning mechanism are arranged in sequence along the rotation direction of the reaction disc, the liquid path module is arranged at the bottom of the movement base, and an emergency tube position is also arranged on the movement base, and an emergency test tube rack is inserted in the emergency tube position, and a plurality of jacks adapted to test tubes are arranged in a ring on the emergency test tube rack.

[0005] As can be seen from the above solution, the reaction disc is used for the reaction of the injected samples and reagents, the photoelectric colorimetric module is used to perform photoelectric colorimetry on the liquid in the reaction cup for biochemical analysis, the reagent adding mechanism is used to add the reagent into the reaction cup after taking the reagent, the sample adding mechanism is used to add the sample solution into the reaction cup, the stirring and mixing mechanism is used to stir and mix the solution in the reaction cup to make it react fully to ensure the accuracy of the detection result, and test tubes are inserted on the emergency test tube rack so that the movement module can work independently, saving the floor area of the equipment. The movement module provided by the present invention has a complete biochemical analyzer function and fully realizes the biochemical detection after adding two kinds of reagents.

[0006] The cleaning mechanism includes a liquid suction linear module, a suction seat arranged at the output end of the liquid suction linear module, and a plurality of groups of suction pipe groups arranged at the bottom of the suction seat. Each suction pipe group includes a flushing pipe and a drainage pipe arranged in parallel at the bottom of the suction seat. The suction pipe group is connected to the bottom of the suction seat through an installation hole. The liquid suction linear module includes a liquid suction seat, a liquid suction motor connected to the liquid suction seat, a lead screw connected to the output end of the liquid suction motor, and a nut seat threadedly connected to the lead screw. The suction seat is connected to the nut seat through a connecting block. Thus, it can be seen that the cleaning mechanism flushes the reaction cup by discharging water through the flushing pipe, and the drainage pipe is used to suck out and discharge the aqueous solution flushed in the reaction cup.

[0007] The stirring and mixing mechanism includes a stirring motor, a mixing motor, a reduction gear set, a mixing connecting piece, a stirring head, and a stirring paddle arranged at the bottom of the stirring head. The reduction gear set is connected to the output end of the mixing motor. The reduction gear set includes a first pulley and a second pulley that is drivingly connected to the first pulley through a conveyor belt. The diameter of the first pulley is smaller than that of the second pulley. The mixing connecting piece is coaxially connected to the second pulley. A limiting slot is provided on the outer edge of the mixing connecting piece through a limiting convex block. A connecting shaft piece is connected in the limiting slot. The stirring head is fixedly connected to the connecting shaft piece through a connecting seat. A slide rail is horizontally arranged above the reduction gear set on the movement mechanism base. The connecting seat is slidably matched with the slide rail. A stirring and cleaning cup is correspondingly arranged below the stirring paddle. Thus, it can be seen that the stirring motor is used to drive the stirring paddle to rotate to achieve stirring, and deceleration is achieved through the driving connection between the first pulley and the second pulley. The mixing motor is used to drive the mixing connecting piece to rotate, so that the stirring head drives the stirring paddle to simultaneously achieve horizontal and vertical movement, and the forward and reverse rotation of the mixing motor is used to achieve the advancement and retraction of the stirring paddle.

[0008] The liquid path module includes a water storage unit, a water supply pipeline unit communicated with the water storage unit, and a waste liquid collection unit. The water storage unit includes a water storage tank, a water pump, a constant pressure device, and an anti-foaming module. The anti-foaming module includes a vacuum pump and an anti-foaming device connected to the output end of the vacuum pump. The output end of the water storage tank is connected to the water inlet of the constant pressure device through the water pump. The water outlet of the constant pressure device is connected to the water inlet end of the anti-foaming module. The water inlet ends and water outlet ends of the sample adding mechanism, the reagent adding mechanism, the stirring and mixing mechanism, and the cleaning mechanism are respectively connected to the anti-foaming device and the waste liquid collection unit. The waste liquid collection unit includes a liquid extraction pump and a waste liquid collection barrel. Thus, it can be seen that the constant pressure device is used to maintain the water pressure of the liquid path system. The anti-foaming device is used to eliminate the bubbles in the water body through the vacuum pump to avoid bubbles adhering to the pipe wall, thereby reducing the risk of contamination. The waste liquid collection barrel is used to suck and collect the waste liquid after cleaning.

[0009] A negative pressure water absorption unit is arranged between the water storage tank and the constant pressure device. The negative pressure water absorption unit includes a diaphragm pump and a buffer tank connected to the diaphragm pump. The buffer tank is provided with an exhaust port, a water inlet interface, and a water outlet interface. The water inlet interface is communicated with the water storage tank. The water outlet interface is connected to the water pump. Thus, it can be seen that the buffer tank discharges the excess gas in the tank through the diaphragm pump to form a negative pressure. The buffer tank is communicated with the water storage tank through the water inlet interface to achieve negative pressure water absorption, so as to replenish water to the liquid path pipeline to achieve automatic water supply of the liquid path system.

[0010] Above the movement base, a display screen is connected by a support arm, and the display screen is electrically connected to the photoelectric colorimetric module. Thus, the display screen is used to display the results of photoelectric colorimetry in the reaction cup.

[0011] On the other hand, the present valve invention also discloses a modular biochemical analyzer, including the movement module, the sample injection and transportation module, and the reagent chamber module. The sample injection and transportation module is assembled outside the sample addition mechanism, and the reagent chamber module is assembled outside the reagent addition mechanism. The sample injection and transportation module includes a sample injection unit, a transmission unit, and a buffer unit arranged in sequence along the sample transportation direction. The sample injection unit and the buffer unit are respectively arranged on both sides of the transmission unit. One side of the sample injection unit and the buffer unit are respectively provided with a first feed port and a second feed port communicating with the transmission unit. The sample injection unit and the buffer unit are both provided with conveyor belt groups. The transmission unit includes a conveyor frame base, a transmission module arranged on the conveyor frame base, a detection optocoupler, and scanners arranged on the inner side walls of both sides of the conveyor frame base. The detection optocoupler is electrically connected to the transmission module, and the scanners are electrically connected to the sample addition mechanism. The transmission module includes two groups of parallel-positioned clamping belts and guide rails arranged between the clamping belts. A number of clamping bumps are equidistantly arranged on the clamping belts. A test tube rack body is clamped and installed on the conveyor frame base through the clamping belts. The bottom of the test tube rack body is slidably matched with the guide rails. A display screen board adapted to the scanners is arranged on the front side of the conveyor seat frame.

[0012] As can be seen from the above solution, the sample injection unit is used to realize the injection of the sample solution. The transmission unit cooperates with the sample addition mechanism to realize the sequential addition of the sample solution in the reaction plate. The detection optocoupler is used to detect the position of the sample test tube in the transmission system and realize positioning through cooperation with the track of the transmission unit. The scanners are used to scan the label information on the test tube during the transmission of the transmission unit. By hanging the reagent chamber module on the movement module, the expansion of multiple test items can be realized. By mounting and assembling the sample injection and transportation module, automatic continuous injection is realized through the track, and the wireless expansion of samples is realized.

[0013] A plurality of jack units for placing test tubes are provided on the test tube rack body. The jack units include outer-layer jacks arranged on opposite sides and two rows of inner-layer jacks arranged inside the outer-layer jacks. The outer-layer jacks and the inner-layer jacks are both arranged at intervals along the length direction, and the outer-layer jacks and the inner-layer jacks are staggered. A first detection slot is provided on the outer circumferential surface of the outer-layer jack, and a second detection slot is provided on the outer circumferential surface of the inner-layer jack. There is an interval between adjacent outer-layer jacks, and the interval is communicated with the second detection slot. An elastic clamp is provided on the jack unit. It can be seen that the first detection slot and the second detection slot are helpful for the code scanning detection of the test tubes on the test tube rack body. The staggered arrangement of the jack units on the test tube rack body expands the storage capacity of the test tubes, enabling the test tube rack to be placed alone without the risk of toppling, thereby realizing a complete set of processes of directly transmitting for sampling and detection after preliminary sampling and expanding the application scenarios.

[0014] The reagent storage module includes a reagent storage seat, on which a reagent storage cover is buckled. Two groups of reagent trays are arranged in parallel in the reagent storage seat. A refrigeration module is provided below the reagent trays in the reagent storage seat through a refrigeration box. Reagent sampling ports are respectively provided on the reagent storage cover corresponding to the two groups of reagent trays. The two groups of reagent trays are respectively coaxially connected to the output ends of two rotation drive modules. A scanning module is provided on the reagent storage seat corresponding to the reagent trays. A plurality of first reagent placement grooves and second reagent placement grooves are annularly arranged on the reagent trays. The second reagent placement grooves are arranged in the inner circle of the first reagent placement grooves. A first slot is provided on the outside of the first reagent placement grooves. There is an interval between adjacent first reagent placement grooves, and the interval is communicated with the second reagent placement grooves to form a second slot. The scanning module includes a scanning seat and a scanner arranged in the scanning seat. A detection port is arranged on the side of the scanning seat facing the reagent trays. It can be seen that the refrigeration module is used to store reagents at low temperature through a refrigeration cycle. The two groups of reagent trays rotate independently and are equipped with two sets of bar code scanners, realizing the automatic fixed quota of reagent positions for each project per day, automatically detecting the reagent expiration date, and being used to realize the addition of two reagents, which is suitable for biochemical analysis of different test items.

[0015] On the other hand, the present invention discloses an assembly method applied to a modular biochemical analyzer. The method includes the following steps:

[0016] S1. Workers produce and process the movement module;

[0017] S1.1. Produce the movement seat, assemble the reaction disk drive module at the bottom of the movement seat, and assemble the reaction disk in the middle of the movement seat and connect it to the output end of the reaction disk drive module;

[0018] S1.2. Arrange the sample adding mechanism, the reagent adding mechanism, the stirring and mixing mechanism, and the cleaning mechanism in sequence along the rotation direction of the reaction disk;

[0019] S1.3. Assemble the liquid path module at the bottom of the movement base, and connect and communicate each pipeline of the liquid path module with the sample adding mechanism, the reagent adding mechanism, the stirring and mixing mechanism, and the cleaning mechanism respectively;

[0020] S1.4. Insert an emergency test tube rack into the emergency cylinder position on the movement base;

[0021] S2. When manufacturing the movement module, manufacture the sample injection and transportation module and the reagent storage module simultaneously;

[0022] S2.1. When manufacturing the sample injection and transportation module, manufacture the sample injection unit, the transmission unit, and the buffer unit simultaneously;

[0023] S3. Assemble the reagent storage module outside the reagent adding mechanism;

[0024] S4. Assemble the transmission unit outside the sample adding mechanism, assemble the sample injection unit and the buffer unit on both sides of the transmission unit respectively, assemble the sample injection unit closely outside the reagent storage module, and connect the first feeding port and the second feeding port on the sample injection unit and the buffer unit with the transmission unit respectively. Description of the Drawings

[0025] Figure 1 is a schematic structural diagram of the movement module;

[0026] Figure 2 is a schematic structural diagram of the biochemical analyzer;

[0027] Figure 3 is a schematic structural diagram of the reaction disk;

[0028] Figure 4 is a schematic structural diagram of the sample adding mechanism;

[0029] Figure 5 is a schematic structural diagram of the stirring and mixing mechanism;

[0030] Figure 6 is a schematic structural diagram of the sample injection and transportation module;

[0031] Figure 7 is a schematic structural diagram of the reagent storage module;

[0032] Figure 8 is a schematic partial structural diagram of the reagent storage module;

[0033] Figure 9 It is a connection schematic diagram of the liquid path module;

[0034] Figure 10 It is a structural schematic diagram of the test tube rack body;

[0035] Figure 11 It is a structural schematic diagram of the reaction cup. Specific implementation manners

[0036] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention.

[0037] As Figures 1 to 11 shown, the present invention discloses a movement module, including a movement base 1; a reaction disk 2, the reaction disk 2 is arranged in the middle of the movement base 1, and a plurality of reaction cups 21 are arranged in a ring in the reaction disk 2; a reaction disk drive module 3, the output end of the reaction disk drive module 3 is connected to the reaction disk 2, and is used to drive the reaction disk 2 to rotate; a photoelectric colorimetric module 4, arranged outside the reaction cup 21, and is used to perform photoelectric colorimetry on the solution in the reaction cup 21;

[0038] a sample adding mechanism 5, used to realize the adding and cleaning of samples; a reagent adding mechanism 6, including a first reagent adding unit 61 and a second reagent adding unit 62, used to realize the adding and cleaning of reagents; a stirring and mixing mechanism 7, including a first stirring and mixing unit 71 and a second stirring and mixing unit 72, used to realize the stirring and mixing of the sample solution and the reagent solution in the reaction cup 21, a cleaning mechanism 8, used to perform injection and drainage cleaning on the reaction cup 21; a liquid path module 9, the liquid path module 9 is respectively connected to the sample adding mechanism 5, the reagent adding mechanism 6, the stirring and mixing mechanism 7 and the cleaning mechanism 8, and is used for liquid path transportation in biochemical reactions for liquid path transportation in biochemical reactions; the sample adding mechanism 5, the reagent adding mechanism 6, the stirring and mixing mechanism 7 and the cleaning mechanism 8 are arranged in sequence along the rotation direction of the reaction disk 2, the liquid path module 9 is arranged at the bottom of the movement base 1, an emergency tube position 10 is also arranged on the movement base 1, an emergency test tube rack 11 is inserted in the emergency tube position 10, and a plurality of jacks 101 adapted to test tubes are arranged in a ring on the emergency test tube rack 11, a display screen 12 is connected above the movement base 1 through a support arm, and the display screen 12 is electrically connected to the photoelectric colorimetric module 4.

[0039] In this embodiment, a first installation groove is provided on the side of the movement base 1 for the reagent adding mechanism 6 to place reagent bottles for emergency use or the first enhanced cleaning bottle. A second installation groove is provided on the side of the movement base 1 for the sample adding mechanism 5 to place sample bottles for emergency use or the second enhanced cleaning bottle, facilitating the movement module to independently complete biochemical analysis or perform secondary enhanced cleaning. The photoelectric colorimetric module is a photoelectric colorimetric box provided on the side of the reaction disc 2. The reaction disc driving module 3 includes a reaction disc driving motor 31, a first transmission wheel connected to the reaction disc driving motor 31, a second transmission wheel 32, and a reaction disc conveyor belt 33 covering the first transmission wheel and the second transmission wheel 32. A detection hole 22 is provided on the reaction disc 2 corresponding to the photoelectric colorimetric box. The reaction cup 21 is arranged in an arc shape. A plurality of liquid storage grooves 211 are provided on the reaction cup 21. A placement flange is provided at the end of the reaction cup 21 for placing on the reaction disc 2. Elastic clamping members 213 are provided on both sides of the reaction cup 21. After the reaction cup 21 is installed in the limit installation groove of the reaction disc, it is clamped by the elastic clamping members 213 to prevent displacement during rotation and ensure the accuracy of sample addition and reagent addition.

[0040] Both the sample adding mechanism 5 and the reagent adding mechanism 6 include a driving motor 51, a lifting motor 52, a rotating shaft 53, a sampling head 54, and a sampling needle 55. The sampling needle 55 is provided at the bottom of the sampling head 54. The sampling head 54 is connected to the output end of the driving motor 51 through the rotating shaft. A sampling needle cleaning pipe 56 is correspondingly provided below the sampling needle 55. The driving motor 51 is connected to the rotating shaft 53 through a first synchronous pulley set. The output end of the lifting motor 52 is connected to a second conveyor pulley set. The rotating shaft 53 is connected to a conveyor belt 58 on the second conveyor pulley set through a coaxial connection seat 57. In this embodiment, the sample adding mechanism 5 and the reagent adding mechanism 6 respectively achieve sample addition and reagent addition through lifting and rotation.

[0041] The cleaning mechanism 8 includes a liquid suction linear module, a suction seat 81 provided at the output end of the liquid suction linear module, and a plurality of groups of suction pipe groups provided at the bottom of the suction seat 81. Each suction pipe group includes a flushing pipe 82 and a drain pipe 83 arranged in parallel at the bottom of the suction seat 81. The suction pipe group is connected to the bottom of the suction seat 81 through an installation hole 811. The liquid suction linear module includes a liquid suction seat 84, a liquid suction motor 85 connected to the liquid suction seat 84, a lead screw 86 connected to the output end of the liquid suction motor 85, and a nut seat 87 threadedly connected to the lead screw 86. The suction seat 81 is connected to the nut seat 87 through a connecting block.

[0042] The stirring and mixing mechanism 7 includes a stirring motor, a mixing motor 72, a reduction gear set, a mixing connecting member 74, a stirring head 75, and a stirring paddle 76 provided at the bottom of the stirring head 75. The reduction gear set is connected to the output end of the mixing motor 72. The reduction gear set includes a first pulley 731 and a second pulley 733 that is drivingly connected to the first pulley 731 through a conveyor belt 732. The diameter of the first pulley 731 is smaller than that of the second pulley 733. The mixing connecting member 74 is coaxially connected to the second pulley 733. A limiting slot 741 is provided on the outer edge of the mixing connecting member 74 through a limiting projection. A connecting shaft member 77 is connected in the limiting slot 741. The stirring head 75 is fixedly connected to the connecting shaft member 77 through a connecting seat 78. A slide rail 79 is horizontally provided on the movement mechanism base 1 above the reduction gear set. The connecting seat 78 is slidably engaged with the slide rail 79. A stirring and cleaning cup 70 is correspondingly provided below the stirring paddle 76.

[0043] The liquid path module 9 includes a water storage unit, a water supply pipeline unit communicating with the water storage unit, and a waste liquid collection unit. The water storage unit includes a water storage tank 91, a water pump 92, a pressure regulator 93, and an anti-foaming module. The anti-foaming module includes a vacuum pump 94 and an anti-foaming device 95 connected to the output end of the vacuum pump 94. The output end of the water storage tank 91 is connected to the water inlet of the pressure regulator 93 through the water pump 92. The water outlet of the pressure regulator 93 is connected to the water inlet end of the anti-foaming module. The water inlet ends and water outlet ends of the sample injection mechanism 5, the reagent injection mechanism 6, the stirring and mixing mechanism 7, and the cleaning mechanism 8 are respectively connected to the anti-foaming device 915 and the waste liquid collection unit. The waste liquid collection unit includes a liquid extraction pump 98 and a waste liquid collection bucket 99. A negative pressure water absorption unit is provided between the water storage tank 91 and the pressure regulator 93. The negative pressure water absorption unit includes a diaphragm pump 96 and a buffer tank 97 connected to the diaphragm pump 96. An exhaust port, a water inlet interface, and a water outlet interface are provided on the buffer tank 97. The water inlet interface communicates with the water storage tank 91. The water outlet interface is connected to the water pump 92.

[0044] On the other hand, the present invention also discloses a modular biochemical analyzer, including the movement module, the sample injection and conveying module 13, and the reagent storage module 14. The sample injection and conveying module 13 is assembled on the outside of the sample adding mechanism 5, and the reagent storage module 14 is assembled on the outside of the reagent adding mechanism 6. The sample injection and conveying module 13 includes a sample injection unit 131, a transmission unit, and a buffer unit 132 arranged in sequence along the sample conveying direction. The sample injection unit 131 and the buffer unit 132 are respectively arranged on both sides of the transmission unit. One side of the sample injection unit 131 and the buffer unit 132 are respectively provided with a first feed port and a second feed port communicated with the transmission unit. The sample injection unit 131 and the buffer unit are both provided with conveyor belt groups. The transmission unit includes a conveyor frame base 133, a transmission module arranged on the conveyor frame base 133, a detection optocoupler 134, and a scanner 135 arranged on both inner side walls of the conveyor frame base 133. The detection optocoupler 134 is electrically connected to the transmission module, and the scanner 135 is electrically connected to the sample adding mechanism 5. The transmission module includes two groups of parallelly arranged clamping belts 1331 and a guide rail 1332 arranged between the clamping belts 1331. A number of clamping bumps are equidistantly arranged on the clamping belts 1331. A test tube rack body 15 is clamped and installed on the conveyor frame base 133 through the clamping belts 1331. The bottom of the test tube rack body 15 is slidably matched with the guide rail 1332. A display panel adapted to the scanner 135 is arranged on the front side of the conveyor seat frame 133.

[0045] A number of jack units for placing test tubes are arranged on the test tube rack body 15. The jack units include outer layer jacks 151 arranged on opposite sides and two rows of inner layer jacks 152 arranged inside the outer layer jacks 151. The outer layer jacks 151 and the inner layer jacks 152 are both arranged at intervals along the length direction. The outer layer jacks 151 and the inner layer jacks 152 are arranged in a staggered manner. A first detection slot 1511 is arranged on the outer circumferential surface of the outer layer jack 151, and a second detection slot 1521 is arranged on the outer circumferential surface of the inner layer jack 152. There is an interval between adjacent outer layer jacks 151, and the interval is communicated with the second detection slot 1521. An elastic clamping member 153 is arranged on the jack unit.

[0046] The reagent bin module 14 includes a reagent bin base 141, on which a reagent bin cover 144 is buckled. Two groups of reagent trays 142 are arranged in parallel in the reagent bin base 141. A refrigeration module is arranged below the reagent trays 142 in the reagent bin base 141 through a refrigeration box 145. Reagent sampling ports 1441 are respectively arranged on the reagent bin cover 144 corresponding to the two groups of reagent trays 142. The two groups of reagent trays 142 are respectively coaxially connected to the output ends of two rotation drive modules. A scanning module is arranged on the reagent bin base 141 corresponding to the reagent trays 142. A number of first reagent placement grooves 1421 and second reagent placement grooves 1422 are annularly arranged on the reagent trays 142. The second reagent placement grooves 1422 are arranged in the inner circle of the first reagent placement grooves 1421. A first slot 1423 is arranged outside the first reagent placement grooves 1421. An interval is arranged between adjacent first reagent placement grooves 1421. The interval communicates with the second reagent placement grooves 1422 to form a second slot 1424. The scanning module includes a scanning base 143 and a scanner arranged in the scanning base 143. A detection port is arranged on the side of the scanning base 143 facing the reagent trays 142.

[0047] The present invention also discloses an assembly method of a modular biochemical analyzer, and the method includes the following steps:

[0048] S1. Workers produce and process the movement module;

[0049] S1.1. Produce the movement base 1, assemble the reaction disk drive module 3 at the bottom of the movement base 1, and assemble the reaction disk 2 in the middle of the movement base 1 and connect it to the output end of the reaction disk drive module 3;

[0050] S1.2. Arrange the sample adding mechanism 5, the reagent adding mechanism 6, the stirring and mixing mechanism 7, and the cleaning mechanism 8 in sequence along the rotation direction of the reaction disk 2;

[0051] S1.3. Assemble the liquid path module 9 at the bottom of the movement base 1, and connect and communicate each pipeline of the liquid path module 9 with the sample adding mechanism 5, the reagent adding mechanism 6, the stirring and mixing mechanism 7, and the cleaning mechanism 8 respectively;

[0052] S1.4. Insert an emergency test tube rack 11 into the emergency tube position 10 on the movement base 1;

[0053] S2. When producing and processing the movement module 1, simultaneously produce and process the sample inlet and conveying module 13 and the reagent bin module 14;

[0054] S2.1. When manufacturing the sample injection and transportation module 13, the sample injection unit 131, the transportation unit, and the buffer unit 132 are manufactured simultaneously.

[0055] S3. Assemble the reagent storage module 14 on the outside of the reagent filling mechanism 6.

[0056] S4. Assemble the transportation unit on the outside of the sample filling mechanism 5, assemble the sample injection unit 131 and the buffer unit 132 on both sides of the transportation unit respectively, assemble the sample injection unit 131 closely on the outside of the reagent storage module 14, and the first feed inlet and the second feed inlet on the sample injection unit 131 and the buffer unit 132 are respectively communicated with the transportation unit.

[0057] Finally, it should be emphasized that the above does not limit the present invention. For those skilled in the art, the present invention can have various changes and modifications. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A core module, characterized in that: include: Movement seat (1); A reaction disk (2), the reaction disk (2) being arranged in the middle of the movement seat (1), and a plurality of reaction cups (21) being arranged in a ring shape inside the reaction disk (2); A reaction disk drive module (3), wherein an output end of the reaction disk drive module (3) is connected to the reaction disk (2) and is used to drive the reaction disk (2) to rotate; A photoelectric colorimetric module (4) is arranged outside the reaction cup (21) and is used to perform photoelectric colorimetry on the solution in the reaction cup (21); A sample filling mechanism (5), used for filling and cleaning the sample; The reagent filling mechanism (6) comprises a first reagent filling unit (61) and a second reagent filling unit (62), and is used to realize the filling and cleaning of the reagent; The stirring and mixing mechanism (7) comprises a first stirring and mixing unit (71) and a second stirring and mixing unit (72), which are used to stir and mix the sample solution and the reagent solution in the reaction cup (21); and the cleaning mechanism (8) is used to perform liquid injection and cleaning on the reaction cup (21); A liquid path module (9), the liquid path module (9) being respectively connected to the sample filling mechanism (5), the reagent filling mechanism (6), the stirring and mixing mechanism (7) and the cleaning mechanism (8), and being used for liquid path transportation in biochemical reactions; The sample filling mechanism (5), the reagent filling mechanism (6), the stirring and mixing mechanism (7) and the cleaning mechanism (8) are arranged in sequence along the rotation direction of the reaction disk (2); the liquid path module (9) is arranged at the bottom of the movement base (1); the movement base (1) is also provided with an emergency tube position (10); an emergency test tube rack (11) is inserted into the emergency tube position (10); and the emergency test tube rack (11) is provided with a plurality of jacks (101) adapted to test tubes in a ring shape.

2. A core module according to claim 1, characterized in that: The cleaning mechanism (8) comprises a liquid suction linear module, a suction seat (81) arranged at the output end of the liquid suction linear module, and a plurality of suction pipe groups arranged at the bottom of the suction seat (81); the suction pipe group comprises a flushing pipe (82) and a discharge pipe (83) arranged in parallel at the bottom of the suction seat (81); the suction pipe group is connected to the bottom of the suction seat (81) through a mounting hole (811); the liquid suction linear module comprises a liquid suction seat (84), a liquid suction motor (85) connected to the liquid suction seat (84), a screw rod (86) connected to the output end of the liquid suction motor (85), and a nut seat (87) threadedly connected to the screw rod (86); the suction seat (81) is connected to the nut seat (87) through a connecting block.

3. A core module according to claim 1, characterized in that: The stirring and mixing mechanism (7) comprises a stirring motor, a mixing motor (72), a reduction wheel group, a mixing connector (74), a stirring head (75), and a stirring paddle (76) arranged at the bottom of the stirring head (75); the reduction wheel group is connected to the output end of the mixing motor (72); the reduction wheel group comprises a first pulley (731) and a second pulley (733) connected to the first pulley (731) by a conveyor belt (732); the diameter of the first pulley (731) is smaller than the diameter of the second pulley (733); the mixing connector (74) is The mixing connecting member (74) is coaxially connected to the second pulley (733); the outer edge of the mixing connecting member (74) is provided with a limiting groove (741) through a limiting protrusion; a connecting shaft (77) is connected inside the limiting groove (741); the stirring head (75) is fixedly connected to the connecting shaft (77) through a connecting seat (78); a slide rail (79) is horizontally provided above the reduction wheel group on the movement seat (1); the connecting seat (78) is slidably matched with the slide rail (79); and a stirring and cleaning cup (70) is correspondingly provided below the stirring paddle (76).

4. A core module according to claim 1, characterized in that: The liquid path module (9) comprises a water storage unit, a water supply pipeline unit connected to the water storage unit, and a waste liquid collection unit. The water storage unit comprises a water storage tank (91), a water pump (92), a constant pressure device (93), and a defoaming module. The defoaming module comprises a vacuum pump (94) and a defoaming device (95) connected to the output end of the vacuum pump (94). The output end of the water storage tank (91) is connected to the water inlet of the constant pressure device (93) through the water pump (92), and the water outlet of the constant pressure device (93) is connected to the water inlet end of the defoaming module. The water inlet end and the water outlet end of the sample filling mechanism (5), the reagent filling mechanism (6), the stirring and mixing mechanism (7), and the cleaning mechanism (8) are respectively connected to the defoaming device (915) and the waste liquid collection unit. The waste liquid collection unit comprises a liquid suction pump (98) and a waste liquid collection bucket (99).

5. A core module according to claim 4, characterized in that: A negative pressure water absorption unit is provided between the water storage tank (91) and the constant pressure device (93), and the negative pressure water absorption unit comprises a diaphragm pump (96) and a buffer tank (97) connected to the diaphragm pump (96); the buffer tank (97) is provided with an exhaust port, a water inlet interface and a water outlet interface; the water inlet interface is connected to the water storage tank (91), and the water outlet interface is connected to the water pump (92).

6. A core module according to claim 1, characterized in that: A display screen (12) is connected above the movement seat (1) via a bracket arm, and the display screen (12) is electrically connected to the photoelectric colorimetric module (4).

7. A modular biochemical analyzer comprising the core module according to any one of claims 1 to 5, characterized in that: The invention comprises a core module, a sample feeding and conveying module (13) and a reagent compartment module (14), wherein the sample feeding and conveying module (13) is assembled on the outside of the sample filling mechanism (5), and the reagent compartment module (14) is assembled on the outside of the reagent filling mechanism (6). The sample feeding and conveying module (13) comprises a sample feeding unit (131), a transmission unit and a buffer unit (132) which are sequentially arranged along the sample conveying direction, wherein the sample feeding unit (131) and the buffer unit (132) are respectively arranged on both sides of the transmission unit, and one side of the sample feeding unit (131) and the buffer unit (132) are respectively provided with a first feed port and a second feed port which are connected to the transmission unit, and the sample feeding unit (131) and the buffer unit are both provided with a conveyor belt group, and the transmission unit comprises a transmission frame seat (133), a transmission frame seat (134) and a transmission frame seat (135) arranged on the transmission frame seat. The invention relates to a transmission frame (133) comprising a transmission module, a detection optical coupler (134) and a scanner (135) arranged on the two inner side walls of the transmission frame (133); the detection optical coupler (134) is electrically connected to the transmission module; the scanner (135) is electrically connected to the sample filling mechanism (5); the transmission module comprises two sets of parallel positioning belts (1331) and a guide rail (1332) arranged between the positioning belts (1331); a plurality of positioning protrusions are equidistantly arranged on the positioning belts (1331); a test tube rack body (15) is mounted on the transmission frame (133) through the positioning belts (1331); the bottom of the test tube rack body (15) is slidably matched with the guide rail (1332); and a display panel adapted to the scanner (135) is arranged on the front side of the transmission frame (133).

8. The modular biochemical analyzer according to claim 7, characterized in that: The test tube rack body (15) is provided with a plurality of socket units for placing test tubes. The socket units include outer sockets (151) arranged on opposite sides and two rows of inner sockets (152) arranged inside the outer sockets (151). The outer sockets (151) and the inner sockets (152) are arranged at intervals along the length direction. The outer sockets (151) and the inner sockets (152) are arranged alternately. The outer circumferential surface of the outer sockets (151) is provided with a first detection groove (1511), and the outer circumferential surface of the inner sockets (152) is provided with a second detection groove (1521). There is a gap between adjacent outer sockets (151), and the gap is connected to the second detection groove (1521). The socket unit is provided with an elastic clamp (153).

9. The modular biochemical analyzer according to claim 7, characterized in that: The reagent compartment module (14) comprises a reagent compartment seat (141), a reagent compartment cover (144) is buckled on the reagent compartment seat (141), two groups of reagent disks (142) are arranged in parallel in the reagent compartment seat (141), a refrigeration module is arranged below the reagent disks (142) through a refrigeration box (145), the reagent compartment cover (144) is respectively provided with reagent sampling ports (1441) corresponding to the two groups of reagent disks (142), the two groups of reagent disks (142) are respectively coaxially connected to the output ends of the two groups of rotation drive modules, the reagent compartment seat (141) is provided with a scanning module corresponding to the reagent disks (142), and the reagent disks (142) are respectively provided with a scanning module. ) is annularly arranged with a plurality of first reagent placement grooves (1421) and second reagent placement grooves (1422), the second reagent placement grooves (1422) are arranged in the inner circle of the first reagent placement grooves (1421), the outer side of the first reagent placement grooves (1421) is provided with a first slot (1423), and a gap is provided between adjacent first reagent placement grooves (1421), and the gap is connected with the second reagent placement grooves (1422) to form a second slot (1424), the scanning module includes a scanning seat (143) and a scanner arranged in the scanning seat (143), and the scanning seat (143) is provided with a detection port on the side facing the reagent disk (142).

10. An assembly method, applied to the modular biochemical analyzer according to any one of claims 7 to 9, characterized in that: The method comprises the following steps: S1. Workers produce and process movement modules; S1.1, producing the movement seat (1), assembling the reaction disk drive module (3) at the bottom of the movement seat (1), assembling the reaction disk (2) at the middle of the movement seat (1) and connecting it to the output end of the reaction disk drive module (3); S1.2, arranging the sample filling mechanism (5), the reagent filling mechanism (6), the stirring and mixing mechanism (7) and the cleaning mechanism (8) in sequence along the rotation direction of the reaction disk (2); S1.3, assembling the liquid circuit module (9) at the bottom of the movement base (1), and connecting and communicating the various pipelines of the liquid circuit module (9) with the sample filling mechanism (5), the reagent filling mechanism (6), the stirring and mixing mechanism (7) and the cleaning mechanism (8); S1.4, inserting an emergency test tube rack (11) into the emergency tube position (10) on the movement base (1); S2. When producing and processing the core module (1), the sample feeding and conveying module (13) and the reagent storage module (14) are produced and processed at the same time; S2.

1. When manufacturing and processing the sample injection and delivery module (13), the sample injection unit (131), the transmission unit and the buffer unit (132) are manufactured and processed at the same time; S3, assembling the reagent storage module (14) on the outside of the reagent filling mechanism (6); S4. Assemble the transmission unit on the outside of the sample filling mechanism (5), and respectively assemble the sample injection unit (131) and the buffer unit (132) on both sides of the transmission unit, wherein the sample injection unit (131) is closely assembled on the outside of the reagent chamber module (14), and the first feed port and the second feed port on the sample injection unit (131) and the buffer unit (132) are respectively connected to the transmission unit.

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