Stem cell low-temperature refrigeration device for disease treatment

Abstract

The invention relates to the technical field of stem cell storage, and provides a stem cell low-temperature refrigeration device for disease treatment, which comprises a refrigeration box body, a stem cell container arrangement plate is arranged in the refrigeration box body, and a plurality of through holes are formed in the top of the stem cell container arrangement plate. According to the stem cell protection device, a container containing stem cells is placed in a through hole, an arc-shaped clamping plate is extruded, a second elastic part is compressed, the bottom of the container is placed in an air bag protection seat, and under the reset acting force of the second elastic part, the arc-shaped clamping plate can clamp and fix the container; and then under the elastic acting force of an elastic rubber ring, the stem cell container can be extruded and fixed to a certain degree, so that when the device bumps in the transportation process, the stem cell container can be prevented from shaking, the situation that the stem cell container is broken can be avoided, and then the situation that stem cells are lost is avoided.

Description

Technical Field

[0001] The present invention relates to the technical field of stem cell storage, and particularly to a cryogenic refrigeration device for stem cells used in disease treatment. Background Art

[0002] Stem cells, also known as "seed cells", are a type of cells with the ability of unlimited or immortal self-renewal, and can produce at least one type of highly differentiated progeny cells. Stem cells have the characteristics of self-renewal, unlimited proliferation and multi-directional differentiation potential. According to their developmental potential, stem cells can be divided into three categories: totipotent stem cells, pluripotent stem cells, and unipotent stem cells; according to the developmental stage they are in, they can be divided into two categories: embryonic stem cells and adult stem cells. Stem cells can be used for clinical cell transplantation to treat various diseases and construct artificial tissues or organs. The diseases suitable for treatment include: tissue necrotic diseases such as myocardial necrosis caused by ischemia, degenerative diseases such as Parkinson's syndrome, and autoimmune diseases such as rheumatoid arthritis, diabetes, and bone and joint diseases.

[0003] In the prior art, in order to maintain the activity of stem cells used in disease treatment, a cryogenic refrigeration device is required to store the stem cells at a low temperature. When the stem cells need to be transported, the container storing the stem cells needs to be placed in the cryogenic refrigeration device. However, the current fixing effect of the stem cell container placed in the cryogenic refrigeration device is not good. When the transportation process is bumpy, it is easy for the stem cell container to shake, and even collide and break, resulting in the loss of stem cells. Summary of the Invention

[0004] The purpose of the present invention is to solve the problem existing in the prior art that in order to maintain the activity of stem cells used in disease treatment, a cryogenic refrigeration device is required to store the stem cells at a low temperature. When the stem cells need to be transported, the container storing the stem cells needs to be placed in the cryogenic refrigeration device. However, the current fixing effect of the stem cell container placed in the cryogenic refrigeration device is not good. When the transportation process is bumpy, it is easy for the stem cell container to shake, and even collide and break, resulting in the loss of stem cells.

[0005] To achieve the above object, the present invention adopts the following technical solution: A cryogenic refrigeration device for stem cells used in disease treatment, comprising: a refrigeration box body, wherein a stem cell container arrangement plate is arranged inside the refrigeration box body, a plurality of through holes are formed in the top of the stem cell container arrangement plate, two circular holes are symmetrically formed in the inner walls of the plurality of through holes, elastic members II are arranged inside the plurality of circular holes, round rods are movably embedded inside the plurality of circular holes, one ends of the plurality of round rods are respectively fixedly installed at one ends of the plurality of elastic members II, the other ends of the plurality of elastic members II are respectively fixedly installed on one side of the inner walls of the plurality of circular holes, the other ends of the plurality of round rods are all fixedly installed with arc-shaped clamping plates, the plurality of arc-shaped clamping plates are respectively symmetrically and movably embedded inside the plurality of through holes, elastic sponge sheets are fixedly installed on the inner sides of the arc surfaces of the plurality of arc-shaped clamping plates, and elastic rubber rings are fixedly embedded in the inner walls of the plurality of through holes near the bottom.

[0006] Preferably, two sliding grooves are symmetrically formed on the opposite sides of the inner wall of the refrigeration box body near the bottom, sliders are movably embedded inside the plurality of sliding grooves, one sides of the plurality of sliders are fixedly installed with a movable plate, and the outer surface of the movable plate is movably embedded inside the refrigeration box body. When the movable plate vibrates up and down, it can drive the sliders to slide up and down along the inside of the sliding grooves.

[0007] Preferably, dampers are fixedly installed at the four corners of the bottom of the inner wall of the refrigeration box body, one ends of the plurality of dampers are respectively fixedly installed at the bottoms of the plurality of sliders, buffer springs are movably sleeved on the outer surfaces of the plurality of dampers, one ends of the plurality of buffer springs are respectively fixedly installed at the bottoms of the plurality of sliders, and the other ends of the plurality of buffer springs are respectively fixedly installed at the four corners of the bottom of the inner wall of the refrigeration box body. Under the interaction of the dampers and the buffer springs, a certain vibration damping and buffering effect is achieved.

[0008] Preferably, a cylindrical airbag is fixedly installed at the center of the bottom of the movable plate, the bottom of the cylindrical airbag is fixedly installed at the center of the inner wall bottom of the refrigerating box body, two L-shaped pipes are symmetrically and fixedly embedded on the outer surface of the cylindrical airbag, the outer surfaces of the two L-shaped pipes are symmetrically and fixedly embedded on the outer surface of the movable plate, one end of each of the two L-shaped pipes is fixedly installed with a diversion pipe, a plurality of shunt pipes are equidistantly and fixedly embedded on the outer surface of each of the two diversion pipes, a plurality of airbag protection seats are fixedly installed on the top of the movable plate, one end of each of a plurality of the shunt pipes is respectively fixedly embedded on the outer surface of one of the plurality of airbag protection seats, and one end of each of the other plurality of shunt pipes is respectively fixedly embedded in pairs and symmetrically on the outer surface of the other plurality of airbag protection seats. The cylindrical airbag, the two L-shaped pipes, the two diversion pipes, the plurality of shunt pipes and the plurality of airbag protection seats are communicated with each other. Through the up-and-down vibration of the movable plate, the cylindrical airbag can be squeezed to a certain extent, so that the gas inside the cylindrical airbag sequentially passes through the L-shaped pipes, the diversion pipes and the shunt pipes and enters the inside of the airbag protection seats, causing the airbag protection seats to expand, thereby squeezing and fixing the bottom of the stem cell container to a certain extent.

[0009] Preferably, two vertical plates are symmetrically and fixedly installed on the top of the movable plate. One side of each of the two vertical plates close to the top is movably embedded with a limiting rod. Limiting holes are formed on the opposite sides of the stem cell container layout plate. One end of each of the two limiting rods is respectively movably embedded in the two limiting holes. By inserting the limiting rods into the limiting holes, the stem cell container layout plate and the movable plate can be kept in a relatively fixed state.

[0010] Preferably, elastic members I are arranged on the outer surfaces of the two limiting rods. One end of each of the two elastic members I is respectively fixedly installed on one side of each of the two vertical plates close to the top, and the other end of each of the two elastic members I is respectively fixedly installed on the other end of each of the two limiting rods. Under the restoring force of the elastic members I, the limiting rods can be inserted into the limiting holes to realize the limitation of the stem cell container layout plate.

[0011] Preferably, positioning rods are fixedly installed at the four corners of the top of the movable plate. Limiting rings are fixedly sleeved on the outer surfaces of the far ends of the plurality of positioning rods away from the movable plate. Two fixing blocks are symmetrically and fixedly installed on the opposite sides of the stem cell container layout plate. One end of each of the plurality of positioning rods is respectively movably embedded in the plurality of fixing blocks. Through the above settings, a certain positioning effect is achieved.

[0012] Preferably, a refrigerator is fixedly installed on one side of the refrigerating box body near the center. Both ends of the refrigerator are fixedly installed with cold air pipes. One ends of the two cold air pipes are respectively fixedly embedded on the opposite sides of the refrigerating box body. One ends of the two cold air pipes are communicated with the interior of the refrigerating box body. The refrigerator is controlled by a controller to start, so that cold air is conveyed into the interior of the refrigerating box body through the cold air pipes, and the interior of the refrigerating box body is in a low-temperature state.

[0013] Preferably, the top of the refrigerating box body is connected with a box cover through a hinge. An elastic sponge board is fixedly installed at the bottom of the box cover. A handle is fixedly installed on the top of the box cover. Two sub-buckles are symmetrically and fixedly installed on one side of the box cover. Two mother-buckles are symmetrically and fixedly installed on the other side of the refrigerating box body near the top. The two mother-buckles are respectively engaged with the two sub-buckles. Through the above settings, it is convenient to open or close the box cover.

[0014] Preferably, support legs are fixedly installed at the four corners of the bottom of the refrigerating box body. Anti-slip pads are fixedly installed at the bottoms of the plurality of support legs. Through the setting of the anti-slip pads, the stability of this device during placement can be improved.

[0015] Compared with the prior art, the advantages and positive effects of the present invention are as follows. 1. In the present invention, by placing the container containing stem cells into the through hole and squeezing the arc-shaped clamping plate, two adjacent arc-shaped clamping plates move in opposite directions, synchronously driving the round rod to move into the round hole, compressing the elastic member II, squeezing the elastic rubber ring, and placing the bottom of the container inside the airbag protection seat. Under the restoring force of the elastic member II, the arc-shaped clamping plate can clamp and fix the container. Then, under the elastic force of the elastic rubber ring, the container can be squeezed and fixed to a certain extent. By inflating the airbag protection seat, the bottom of the stem cell container can be squeezed and fixed to a certain extent. In this way, when the device bumps during transportation, the stem cell container can be prevented from shaking, thereby avoiding the situation of the stem cell container being broken and further avoiding the loss of stem cells.

[0016] 2. In the present invention, under the interaction of the damper and the buffer spring, the vibration amplitude of the movable plate and the stem cell container arrangement plate can be reduced, and at the same time, the slider slides up and down to a certain extent inside the chute, which can reduce the vibration amplitude of the stem cell container arrangement plate, thereby reducing the vibration amplitude of the stem cell container and further improving the safety of stem cell transportation.

[0017] 3. In the present invention, by manually pulling the limit rod to one side to disengage it from the inside of the limit hole, the limitation on the stem cell container placement plate is released, and at the same time, the first elastic member is stretched. At this time, the stem cell container placement plate can be taken out upward, so that the fixing block is disengaged from the positioning rod. In this way, by taking out the stem cell container placement plate as a whole, the stem cell container can be taken out as a whole, thereby improving the efficiency of taking out the stem cell container. Brief Description of the Drawings

[0018] Figure 1 is a schematic structural view of a stem cell cryogenic refrigeration device for disease treatment provided by the present invention; Figure 2 is a schematic side view structure of a stem cell cryogenic refrigeration device for disease treatment provided by the present invention; Figure 3 is a schematic bottom view structure of a stem cell cryogenic refrigeration device for disease treatment provided by the present invention; Figure 4 is a schematic internal structure view of a stem cell cryogenic refrigeration device for disease treatment provided by the present invention; Figure 5 is a schematic structure view of an airbag protection seat of a stem cell cryogenic refrigeration device for disease treatment provided by the present invention; Figure 6 is a schematic structure view of a chute of a stem cell cryogenic refrigeration device for disease treatment provided by the present invention; Figure 7 is a schematic sectional view structure of a stem cell cryogenic refrigeration device for disease treatment provided by the present invention; Figure 8 is a stem cell cryogenic refrigeration device for disease treatment provided by the present invention Figure 7 Schematic enlarged view of part A in

[0019] Legend Explanation: 1. Refrigeration box body; 101. Box cover; 102. Handle; 103. Sub - buckle; 104. Mother - buckle; 105. Support leg; 106. Anti - slip pad; 107. Refrigerator; 108. Cold air pipeline; 109. Chute; 110. Elastic sponge board; 2. Movable plate; 201. Positioning rod; 202. Fixing block; 203. Vertical plate; 204. Limit rod; 205. First elastic member; 206. Limit ring; 3. Stem cell container placement plate; 301. Through - hole; 302. Arc - shaped clamping plate; 303. Limit hole; 304. Round hole; 305. Round rod; 306. Second elastic member; 307. Elastic sponge sheet; 308. Elastic rubber ring; 4. Slide block; 401. Damper; 402. Buffer spring; 5. Cylindrical airbag; 501. L - shaped pipe; 502. Diversion pipe; 503. Shunt pipe; 504. Airbag protection seat. Detailed Embodiment

[0020] The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Apparently, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0021] Example 1, as Figure 1 - Figure 8As shown in the figure, the present invention provides a technical solution: a cryogenic refrigeration device for stem cells used in disease treatment, including: a refrigeration box body 1, an inner part of the refrigeration box body 1 is provided with a stem cell container arrangement board 3, a plurality of through holes 301 are opened at the top of the stem cell container arrangement board 3, two circular holes 304 are symmetrically opened on the inner walls of the plurality of through holes 301, elastic members II 306 are arranged inside the plurality of circular holes 304, round rods 305 are movably embedded inside the plurality of circular holes 304, one ends of the plurality of round rods 305 are respectively fixedly installed at one ends of the plurality of elastic members II 306, the other ends of the plurality of elastic members II 306 are respectively fixedly installed on one side of the inner walls of the plurality of circular holes 304, arc-shaped clamping plates 302 are fixedly installed at the other ends of the plurality of round rods 305, the plurality of arc-shaped clamping plates 302 are respectively movably embedded in the plurality of through holes 301 in pairs and symmetrically, elastic sponge sheets 307 are fixedly installed on the inner sides of the arc surfaces of the plurality of arc-shaped clamping plates 302, elastic rubber rings 308 are fixedly embedded on the inner walls of the plurality of through holes 301 near the bottom, a cylindrical air bag 5 is fixedly installed at the center of the bottom of the movable plate 2, the bottom of the cylindrical air bag 5 is fixedly installed at the center of the inner wall of the bottom of the refrigeration box body 1, two L-shaped pipes 501 are symmetrically and fixedly embedded on the outer surface of the cylindrical air bag 5, the outer surfaces of the two L-shaped pipes 501 are symmetrically and fixedly embedded on the outer surface of the movable plate 2, one ends of the two L-shaped pipes 501 are respectively fixedly installed with diversion pipes 502, a plurality of shunt pipes 503 are equidistantly and fixedly embedded on the outer surfaces of the two diversion pipes 502, a plurality of air bag protection seats 504 are fixedly installed on the top of the movable plate 2, one ends of a plurality of the shunt pipes 503 are respectively fixedly embedded on the outer surfaces of a plurality of the air bag protection seats 504, one ends of the other plurality of shunt pipes 503 are respectively fixedly embedded in pairs and symmetrically on the outer surfaces of the other plurality of air bag protection seats 504, the cylindrical air bag 5, the two L-shaped pipes 501, the two diversion pipes 502, the plurality of shunt pipes 503 and the plurality of air bag protection seats 504 are communicated with each other, a refrigerator 107 is fixedly installed on one side of the refrigeration box body 1 near the center, cold air pipes 108 are fixedly installed at both ends of the refrigerator 107, one ends of the two cold air pipes 108 are respectively fixedly embedded on the opposite sides of the refrigeration box body 1, and one ends of the two cold air pipes 108 are communicated with the inside of the refrigeration box body 1. The top of the refrigeration box body 1 is hinged with a box cover 101, an elastic sponge board 110 is fixedly installed at the bottom of the box cover 101, a handle 102 is fixedly installed at the top of the box cover 101, two sub-buckles 103 are symmetrically and fixedly installed on one side of the box cover 101, two mother-buckles 104 are symmetrically and fixedly installed on the other side of the refrigeration box body 1 near the top, and the two mother-buckles 104 are respectively snap-connected with the two sub-buckles 103. Support legs 105 are fixedly installed at the four corners of the bottom of the refrigeration box body 1, and anti-slip pads 106 are fixedly installed at the bottoms of the plurality of support legs 105.

[0022] In one embodiment, the second elastic member 306 is movably embedded inside the circular hole 304. The second elastic member 306 uses a compression spring. The controller is used to control the start of the refrigerator 107, so that it conveys cold air to the inside of the refrigerated box body 1 through the cold air duct 108, making the inside of the refrigerated box body 1 in a low-temperature state. Then, by releasing the engaged state of the sub-button 103 and the mother-button 104, the box cover 101 is opened. Next, the container containing stem cells is placed inside the through hole 301, making the bottom of the container contact the inner arc surface of the arc-shaped clamping plate 302 and extruding it, causing two adjacent arc-shaped clamping plates 302 to move in opposite directions, synchronously driving the round rod 305 to move inside the circular hole 304, compressing the second elastic member 306. During the downward insertion of the container, the elastic rubber ring 308 is extruded, making the bottom of the container placed inside the airbag protection seat 504. Under the reset force of the second elastic member 306, the arc-shaped clamping plate 302 can clamp and fix the container. Then, under the elastic force of the elastic rubber ring 308, the container can be extruded and fixed to a certain extent. In this way, when the device jolts during transportation, the stem cell container can be prevented from shaking, thus avoiding the situation of the stem cell container being broken and further avoiding the loss of stem cells. Synchronously, through the up-and-down vibration of the movable plate 2, the cylindrical airbag 5 can be extruded to a certain extent, making the gas inside the cylindrical airbag 5 pass through the L-shaped pipe 501, the diversion pipe 502, and the shunt pipe 503 in sequence and enter the airbag protection seat 504, causing the airbag protection seat 504 to expand, so as to extrude and fix the bottom of the stem cell container to a certain extent.

[0023] In another embodiment, the second elastic member 306 is movably embedded inside the circular hole 304. The second elastic member 306 uses a spring piece. The refrigerator 107 is controlled by a controller to start, and it conveys cold air into the interior of the refrigerated box body 1 through the cold air pipeline 108, so that the interior of the refrigerated box body 1 is in a low-temperature state. Then, the engaged state of the sub-button 103 and the mother button 104 is released, and the box cover 101 is opened. Then, the container containing stem cells is placed inside the through hole 301, and the bottom of the container contacts the inner arc surface of the arc-shaped clamping plate 302 and is extruded, causing two adjacent arc-shaped clamping plates 302 to move in opposite directions, synchronously driving the round rod 305 to move into the circular hole 304, compressing the second elastic member 306. During the downward insertion of the container, the elastic rubber ring 308 is extruded, and the bottom of the container is placed inside the airbag protection seat 504. Under the restoring force of the second elastic member 306, the arc-shaped clamping plate 302 can clamp and fix the container. Then, under the elastic force of the elastic rubber ring 308, the container can be extruded and fixed to a certain extent. In this way, when the device jolts during transportation, the stem cell container can be prevented from shaking, thus avoiding the situation of the stem cell container cracking and further avoiding the loss of stem cells. Synchronously, through the up-and-down vibration of the movable plate 2, the cylindrical airbag 5 can be extruded to a certain extent, so that the gas inside the cylindrical airbag 5 passes through the L-shaped pipe 501, the diversion pipe 502, and the shunt pipe 503 in sequence and enters the airbag protection seat 504, causing the airbag protection seat 504 to expand, thereby extruding and fixing the bottom of the stem cell container to a certain extent.

[0024] Embodiment 2, as Figure 1 - Figure 8 shown, two sliding grooves 109 are symmetrically formed on the opposite sides of the inner wall of the refrigerated box body 1 near the bottom. A slider 4 is movably embedded inside each of the plurality of sliding grooves 109. One side of each of the plurality of sliders 4 is fixedly installed with a movable plate 2. The outer surface of the movable plate 2 is movably embedded inside the refrigerated box body 1. Dampers 401 are fixedly installed at the four corners of the bottom inner wall of the refrigerated box body 1. One end of each of the plurality of dampers 401 is fixedly installed at the bottom of each of the plurality of sliders 4. A buffer spring 402 is movably sleeved on the outer surface of each of the plurality of dampers 401. One end of each of the plurality of buffer springs 402 is fixedly installed at the bottom of each of the plurality of sliders 4, and the other end of each of the plurality of buffer springs 402 is fixedly installed at the four corners of the bottom inner wall of the refrigerated box body 1.

[0025] In this embodiment, when the device generates vertical vibration due to jolting during transportation, the vibration amplitude of the movable plate 2 and the stem cell container arrangement plate 3 can be reduced through the interaction of the damper 401 and the buffer spring 402. Synchronously, the slider 4 slides up and down within a certain range inside the chute 109, which can reduce the vibration amplitude of the stem cell container arrangement plate 3, thereby reducing the vibration amplitude of the stem cell container, and further improving the safety of stem cell transportation.

[0026] Embodiment 3, as Figure 1 - Figure 8 As shown in the figure, two vertical plates 203 are symmetrically and fixedly installed at the top of the movable plate 2. One side of each of the two vertical plates 203 near the top is movably embedded with a limiting rod 204. Limiting holes 303 are formed on the opposite sides of the stem cell container arrangement plate 3. One end of each of the two limiting rods 204 is movably embedded in the two limiting holes 303 respectively. Elastic members 205 are arranged on the outer surfaces of the two limiting rods 204. One end of each of the two elastic members 205 is fixedly installed on one side of each of the two vertical plates 203 near the top, and the other end of each of the two elastic members 205 is fixedly installed on the other end of the two limiting rods 204. Positioning rods 201 are fixedly installed at the four corners of the top of the movable plate 2. Limiting rings 206 are fixedly sleeved on the outer surfaces of the ends of the plurality of positioning rods 201 far from the movable plate 2. Two fixing blocks 202 are symmetrically and fixedly installed on the opposite sides of the stem cell container arrangement plate 3. One end of each of the plurality of positioning rods 201 is movably embedded in the plurality of fixing blocks 202 respectively.

[0027] In one embodiment, the elastic member 205 is movably sleeved on the outer surface of the limiting rod 204, and the elastic member 205 is a compression spring. By manually pulling the limiting rod 204 to one side to disengage it from the inside of the limiting hole 303 and releasing the limitation on the stem cell container arrangement plate 3, the elastic member 205 is stretched synchronously. At this time, the stem cell container arrangement plate 3 can be taken out upward, and the fixing block 202 is disengaged from the positioning rod 201. In this way, by taking out the stem cell container arrangement plate 3 as a whole, the stem cell container can be taken out as a whole, thereby improving the efficiency of taking out the stem cell container. On the contrary, by placing the stem cell container arrangement plate 3 into the refrigerated box body 1 and sleeving the fixing block 202 on the outer surface of the positioning rod 201, the positioning of the stem cell container arrangement plate 3 is completed, and under the action of the limiting ring 206, the limiting effect on the stem cell container arrangement plate 3 is achieved. Then, by releasing the limiting rod 204, it can be inserted into the limiting hole 303 under the restoring force of the elastic member 205 to limit the stem cell container arrangement plate 3 and keep the stem cell container arrangement plate 3 in a relatively fixed state with the movable plate 2.

[0028] In another embodiment, the first elastic member 205 is movably sleeved on the outer surface of the limiting rod 204. The first elastic member 205 is a spring piece. By manually pulling the limiting rod 204 to one side, it is disengaged from the inside of the limiting hole 303, releasing the limitation on the stem cell container arrangement plate 3. At the same time, the first elastic member 205 is stretched. At this time, the stem cell container arrangement plate 3 can be taken out upward, so that the fixing block 202 is disengaged from the positioning rod 201. In this way, by taking out the stem cell container arrangement plate 3 as a whole, the stem cell container can be taken out as a whole, thereby improving the efficiency of taking out the stem cell container. On the contrary, by placing the stem cell container arrangement plate 3 into the interior of the refrigeration box body 1 and sleeving the fixing block 202 on the outer surface of the positioning rod 201, the positioning of the stem cell container arrangement plate 3 is completed. Under the action of the limiting ring 206, the stem cell container arrangement plate 3 is limited. Then, by releasing the limiting rod 204, it can be inserted into the limiting hole 303 under the restoring force of the first elastic member 205 to limit the stem cell container arrangement plate 3, so that the stem cell container arrangement plate 3 and the movable plate 2 are in a relatively fixed state.

[0029] Working principle: When in use, firstly, the controller controls the refrigerator 107 to start, so that it can deliver cold air to the inside of the refrigerated box 1 through the cold air pipe 108, so that the inside of the refrigerated box 1 is in a low temperature state, and then the box cover 101 is opened by releasing the state of engagement between the sub-button 103 and the female button 104, and then the container containing stem cells is placed inside the through hole 301, so that the bottom of the container contacts the inner side of the arc surface of the arc clamping plate 302, and squeezes it, so that the two adjacent arc clamping plates 302 move to the opposite side, and synchronously drives the round rod 305 to move inside the round hole 304, so that the elastic member 2 306 is compressed, and when the container is inserted downward, the elastic rubber ring 308 is squeezed, so that the bottom of the container is placed on the airbag protection Inside the guard seat 504, the arc-shaped clamping plate 302 can clamp and fix the container under the restoring force of the elastic member 306, and then the container can be squeezed and fixed to a certain extent under the elastic force of the elastic rubber ring 308, so that when the device is bumpy during transportation, the stem cell container can be prevented from shaking, thereby preventing the stem cell container from rupturing and further preventing the loss of stem cells. When the device vibrates in the vertical direction due to bumps during transportation, the vibration amplitude of the movable plate 2 and the stem cell container arrangement plate 3 can be slowed down by the interaction of the damper 401 and the buffer spring 402, and the slider 4 can be synchronously moved to a certain amplitude inside the slide groove 109. Sliding up and down can reduce the vibration amplitude of the stem cell container arrangement plate 3, thereby reducing the vibration amplitude of the stem cell container, thereby improving the safety of stem cell transportation. Synchronously, through the up and down vibration of the movable plate 2, the cylindrical airbag 5 can be squeezed to a certain extent, so that the gas inside the cylindrical airbag 5 passes through the L-shaped tube 501, the guide tube 502 and the shunt tube 503 in sequence, and enters the inside of the airbag protection seat 504, so that the airbag protection seat 504 expands, thereby squeezing and fixing the bottom of the stem cell container to a certain extent. When the stem cell container needs to be taken out as a whole, the limiting rod 204 can be manually pulled to one side to disengage it from the inside of the limiting hole 303, thereby releasing the limit on the stem cell container arrangement plate 3, and synchronously making the elastic The stem cell container arrangement plate 3 is stretched by the elastic member 205, and the stem cell container arrangement plate 3 can be taken out upwards at this time, so that the fixing block 202 is separated from the positioning rod 201. In this way, the stem cell container arrangement plate 3 can be taken out as a whole by taking out the stem cell container arrangement plate 3, thereby improving the efficiency of taking out the stem cell container. Conversely, the stem cell container arrangement plate 3 is placed into the interior of the cold storage box 1, and the fixing block 202 is sleeved on the outer surface of the positioning rod 201, so as to complete the positioning of the stem cell container arrangement plate 3, and under the action of the limiting ring 206, the stem cell container arrangement plate 3 is limited. Then, by loosening the limiting rod 204, the limiting rod 204 can be inserted into the interior of the limiting hole 303 under the resetting force of the elastic member 205, so as to limit the stem cell container arrangement plate 3.Keep the stem cell container arrangement plate 3 in a relatively fixed state with the movable plate 2.

[0030] As described above, it is only the preferred embodiment of the present invention, and it is not a limitation to the present invention in other forms. Any person skilled in the art may use the disclosed technical content to make changes or modifications into equivalent embodiments with equivalent changes and apply them to other fields. However, as long as it does not depart from the technical solution content of the present invention, any simple modification, equivalent change and modification made to the above embodiments based on the technical essence of the present invention still fall within the protection scope of the technical solution of the present invention.

Claims

1. A low-temperature cold storage device for stem cells for disease treatment, characterized in that: include: A refrigerating box (1), wherein a stem cell container arrangement plate (3) is arranged inside the refrigerating box (1), a plurality of through holes (301) are provided on the top of the stem cell container arrangement plate (3), two circular holes (304) are symmetrically provided on the inner walls of the plurality of through holes (301), elastic members (306) are arranged inside the plurality of circular holes (304), round rods (305) are movably embedded inside the plurality of circular holes (304), and one end of the plurality of circular rods (305) is respectively fixedly mounted on the plurality of elastic members (306). One end, the other ends of the plurality of elastic members (306) are respectively fixedly mounted on one side of the inner wall of the plurality of circular holes (304), the other ends of the plurality of round rods (305) are all fixedly mounted with arc-shaped clamping plates (302), the plurality of arc-shaped clamping plates (302) are respectively symmetrically and movably embedded in the interior of the plurality of through holes (301), the inner sides of the arc surfaces of the plurality of arc-shaped clamping plates (302) are all fixedly mounted with elastic sponge sheets (307), and the inner walls of the plurality of through holes (301) near the bottom are all fixedly embedded with elastic rubber rings (308).

2. The low-temperature cold storage device for stem cells for disease treatment according to claim 1, characterized in that: Two slide grooves (109) are symmetrically provided on opposite sides of the inner wall of the bottom of the refrigerating box body (1), and sliders (4) are movably embedded in the interior of the plurality of slide grooves (109). A movable plate (2) is fixedly installed on one side of the plurality of sliders (4), and the outer surface of the movable plate (2) is movably embedded in the interior of the refrigerating box body (1).

3. The low-temperature cold storage device for stem cells for disease treatment according to claim 2, characterized in that: Dampers (401) are fixedly mounted at the four corners of the bottom of the inner wall of the refrigerating box body (1), one ends of the plurality of dampers (401) are respectively fixedly mounted at the bottoms of the plurality of sliders (4), and buffer springs (402) are movably sleeved on the outer surfaces of the plurality of dampers (401), one ends of the plurality of buffer springs (402) are respectively fixedly mounted at the bottoms of the plurality of sliders (4), and the other ends of the plurality of buffer springs (402) are respectively fixedly mounted at the four corners of the bottom of the inner wall of the refrigerating box body (1).

4. The low-temperature cold storage device for stem cells for disease treatment according to claim 3, characterized in that: A cylindrical air bag (5) is fixedly mounted at the center of the bottom of the movable plate (2); the bottom of the cylindrical air bag (5) is fixedly mounted at the center of the bottom of the inner wall of the refrigerating box (1); two L-shaped tubes (501) are symmetrically fixedly embedded on the outer surface of the cylindrical air bag (5); the outer surfaces of the two L-shaped tubes (501) are symmetrically fixedly embedded on the outer surface of the movable plate (2); one end of the two L-shaped tubes (501) is fixedly mounted with a guide tube (502); the outer surfaces of the two guide tubes (502) are equidistantly fixedly embedded with a plurality of flow diversion tubes. (503), a plurality of airbag protection seats (504) are fixedly installed on the top of the movable plate (2), wherein one end of the plurality of shunt pipes (503) is respectively fixedly embedded in the outer surface of the plurality of airbag protection seats (504), and one end of another plurality of shunt pipes (503) is respectively symmetrically fixedly embedded in the outer surface of another plurality of airbag protection seats (504), and the cylindrical airbag (5), the two L-shaped pipes (501), the two guide pipes (502), the plurality of shunt pipes (503) and the plurality of airbag protection seats (504) are connected.

5. The low-temperature cold storage device for stem cells for disease treatment according to claim 4, characterized in that: Two vertical plates (203) are symmetrically fixedly mounted on the top of the movable plate (2), and limiting rods (204) are movably embedded on one side of the two vertical plates (203) close to the top. Limiting holes (303) are provided on the opposite side of the stem cell container arrangement plate (3), and one end of the two limiting rods (204) is movably embedded in the inside of the two limiting holes (303), respectively.

6. The low-temperature cold storage device for stem cells for disease treatment according to claim 5, characterized in that: The outer surfaces of the two limit rods (204) are each provided with an elastic member 1 (205), one end of the two elastic members 1 (205) is respectively fixedly mounted on one side of the two vertical plates (203) close to the top, and the other end of the two elastic members 1 (205) is respectively fixedly mounted on the other end of the two limit rods (204).

7. The low-temperature cold storage device for stem cells for disease treatment according to claim 5, characterized in that: Positioning rods (201) are fixedly mounted at the four corners of the top of the movable plate (2); a plurality of the positioning rods (201) are fixedly sleeved with a limiting ring (206) on the outer surfaces of one end away from the movable plate (2); two fixing blocks (202) are symmetrically fixedly mounted on the opposite side of the stem cell container arrangement plate (3); and one end of the plurality of positioning rods (201) is movably embedded in the interior of the plurality of fixing blocks (202).

8. The low-temperature cold storage device for stem cells for disease treatment according to claim 4, characterized in that: A refrigerating machine (107) is fixedly mounted on one side of the refrigerating box (1) near the center, and cold air pipes (108) are fixedly mounted on both ends of the refrigerating machine (107). One end of the two cold air pipes (108) are respectively fixedly embedded in opposite sides of the refrigerating box (1), and one end of the two cold air pipes (108) are connected to the interior of the refrigerating box (1).

9. The low-temperature cold storage device for stem cells for disease treatment according to claim 8, characterized in that: The top of the refrigerating box body (1) is connected to a box cover (101) via a hinge, an elastic sponge plate (110) is fixedly mounted on the bottom of the box cover (101), a handle (102) is fixedly mounted on the top of the box cover (101), two sub-buckles (103) are symmetrically fixedly mounted on one side of the box cover (101), and two female buckles (104) are symmetrically fixedly mounted on the other side of the refrigerating box body (1) near the top, and the two female buckles (104) are respectively engaged and connected with the two sub-buckles (103).

10. The low-temperature cold storage device for stem cells for disease treatment according to claim 9, characterized in that: Support legs (105) are fixedly mounted at the four corners of the bottom of the refrigeration box body (1), and anti-slip pads (106) are fixedly mounted at the bottoms of the plurality of support legs (105).

Images