Special injector for oncolytic viruses

Abstract

The invention relates to the technical field of injectors, and discloses a special injector for oncolytic viruses, which comprises an injector main body, a piston and an interface assembly, the interface assembly comprises a connecting disc and a plurality of angle adjusting pieces, the middle part of the top end of the connecting disc is fixedly connected with a first connecting pipe, and the output end of the injector main body is fixedly connected with a first threaded head; the first threaded head is in threaded connection with the first connecting pipe, and the angle adjusting pieces are arranged at the bottom end of the connecting disc. The needle head assembly comprises a plurality of connecting pieces, a plurality of length adjusting pieces and a plurality of needle heads, the connecting pieces are connected with the adjusting pieces respectively, the angles of the connecting pieces are adjusted through the length adjusting pieces, the needle heads are connected with the connecting pieces through the length adjusting pieces respectively, and the injection depth of the needle heads is adjusted through the length adjusting pieces. Through the arrangement of the multiple needles, multi-point injection is achieved, mounting and dismounting are convenient and fast, high-pressure-resistant injection can be achieved, meanwhile, the angles, the lengths and the models of the needles are adjusted, and the tumor injector is suitable for tumors of different hardness and sizes.

Description

Technical Field

[0001] The present invention relates to the technical field of syringes, and particularly to a special syringe for oncolytic virus. Background Art

[0002] Intratumoral injection of oncolytic virus is a novel anti-tumor treatment method at present. Currently, conventional syringes have been used for operation, which has deficiencies such as easy drug leakage, insufficient pressure, inaccurate dosage, and insufficient drug infiltration. At present, there is no special syringe for oncolytic virus in clinical practice.

[0003] Therefore, there is an urgent need for a special syringe for oncolytic virus to solve the above problems. Summary of the Invention

[0004] The purpose of the present invention is to provide a special syringe for oncolytic virus to solve the problems existing in the above-mentioned prior art.

[0005] To achieve the above purpose, the present invention provides the following solution: The present invention provides a special syringe for oncolytic virus, including a syringe body and a piston adapted to the syringe body.

[0006] It further includes an interface component, the interface component includes a connection disk and a plurality of angle adjustment members. The middle part of the top end of the connection disk is fixedly connected with a first connecting pipe, the output end of the syringe body is fixedly connected with a first threaded head, and the first threaded head is threadedly connected with the first connecting pipe. A plurality of the angle adjustment members are respectively arranged at the bottom end of the connection disk.

[0007] A needle assembly, including a plurality of connecting members, a plurality of length adjustment members and a plurality of needles. A plurality of the connecting members are respectively connected to a plurality of the adjustment members, and the angle of the connecting members is adjusted through the length adjustment members. A plurality of the needles are respectively connected to the connecting members through the length adjustment members, and the injection depth of the needles is adjusted through the length adjustment members.

[0008] According to the special syringe for oncolytic virus provided by the present invention, the angle adjustment member includes a plurality of adjustment disks. One of the adjustment disks is fixedly connected to the middle part of the bottom end of the connection disk. A plurality of adjustment holes are formed in the bottom end of the connection disk along the circumferential direction, and the remaining plurality of adjustment disks are respectively rotatably connected in the plurality of adjustment holes. A conveying channel is formed in the adjustment disk, one end of the conveying channel is communicated with the connection disk through a pipeline, and a plurality of limiting members are arranged on the adjustment disk, and the plurality of limiting members are respectively connected with the plurality of adjustment disks in a limiting manner.

[0009] According to an oncolytic virus special syringe provided by the present invention, a plurality of threaded holes are axially formed on the outer wall of the connection disk. The limiting member includes a first bolt threadedly connected in the threaded hole. One end of the first bolt extends out of the threaded hole and is fixedly connected with a knob. The other end of the first bolt extends into the adjustment hole and is fixedly connected with a limiting head. A toothed groove is formed on the outer wall of the adjustment disk, and the limiting head is adapted to the toothed groove.

[0010] According to an oncolytic virus special syringe provided by the present invention, the connecting member includes an adjustment cylinder. A second threaded head is fixedly connected to the top end of the adjustment cylinder. A second connecting pipe is fixedly connected to the adjustment disk, and the second threaded head is threadedly connected to the second connecting pipe.

[0011] According to an oncolytic virus special syringe provided by the present invention, the length adjustment member includes a delivery pipe. A slider is fixedly connected to the delivery pipe. The delivery pipe is slidably connected to the adjustment cylinder through the slider. External threads are formed on the outer side wall of the delivery pipe. An adjustment ring is rotatably connected to the bottom end of the adjustment cylinder. Internal threads are formed on the inner side wall of the adjustment ring, and the external threads are adapted to the internal threads.

[0012] According to an oncolytic virus special syringe provided by the present invention, a clamping member is further included. A third connecting pipe is fixedly connected to the bottom end of the delivery pipe. A connecting head is fixedly connected to the end of the needle away from the tip. The third connecting pipe is inserted into the connecting head, and the clamping member is arranged on the delivery pipe to clamp the connecting head.

[0013] According to an oncolytic virus special syringe provided by the present invention, the clamping member includes a plurality of clamping plates. One ends of the plurality of clamping plates are circumferentially fixedly connected to the bottom end of the delivery pipe. A clamping head is fixedly connected to the other end of the clamping plate. A threaded sleeve is sleeved on the clamping plate. When the threaded sleeve is threadedly connected to the outer wall of the clamping plate, the clamping head is in contact with the connecting head.

[0014] According to an oncolytic virus special syringe provided by the present invention, a pressure release valve is arranged on the syringe body.

[0015] According to an oncolytic virus special syringe provided by the present invention, handles are fixedly connected to both sides of the top end of the syringe body, and anti-slip pads are fixedly connected to the handles.

[0016] According to an oncolytic virus special syringe provided by the present invention, the syringe body is a metal syringe, and a transparent scale window is arranged on the syringe body.

[0017] Compared with the prior art, the present invention has the following advantages and technical effects:

[0018] A special syringe for oncolytic virus provided by the present invention, when in use, connects the connecting disk to the syringe body through the first connecting pipe and the first threaded head, installs the needle on the length adjusting member, and the length adjusting member is connected to the angle adjusting member through the connecting member. The angle of the needle is adjusted through the provided angle adjusting member, and the injection length of the needle is adjusted through the provided length adjusting member, so as to adapt to different usage situations. By setting a plurality of needles in this application, multi-point injection is realized, and at the same time, the installation and disassembly are convenient. The angle, length and model of the needle can be adjusted to adapt to tumors of different hardness and sizes. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for use in the embodiments. Obviously, the following described drawings are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings:

[0020] Figure 1 Schematic diagram of the syringe body structure of the present invention;

[0021] Figure 2 Schematic diagram of the connecting disk structure of the present invention;

[0022] Figure 3 For the present invention Figure 2 Partial enlarged view at A in;

[0023] Figure 4 Schematic diagram of the state where the needle of the present invention extends;

[0024] Figure 5 Schematic diagram of the state where the needle of the present invention adjusts the extended length;

[0025] Figure 6 Schematic diagram of the state where the clamping member of the present invention is not clamped;

[0026] Figure 7 Schematic diagram of the structure of Embodiment 2 of the present invention;

[0027] Among them, 1. Syringe body; 2. Piston; 3. Connecting disk; 4. First connecting pipe; 5. First threaded head; 6. Needle; 7. Adjusting disk; 8. Adjusting hole; 9. Delivery channel; 10. Pipe; 11. First bolt; 12. Knob; 13. Limiting head; 14. Adjusting cylinder; 15. Second threaded head; 16. Second connecting pipe; 17. Delivery pipe; 18. Slide block; 19. Adjusting ring; 20. Third connecting pipe; 21. Connecting head; 22. Clamping plate; 23. Clamping head; 24. Threaded sleeve; 25. Pressure release valve; 26. Handle; 27. Anti-slip pad; 28. Transparent scale window. DETAILED DESCRIPTION OF THE INVENTION

[0028] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0029] To make the above objects, features, and advantages of the present invention more obvious and understandable, the present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0030] Embodiment 1:

[0031] Referring to Figures 1 - 6 , the present invention provides a special syringe for oncolytic virus, which includes a syringe body 1 and a piston 2 adapted to the syringe body 1.

[0032] It further includes an interface component, and the interface component includes a connection disk 3 and a plurality of angle adjustment members. A first connection pipe 4 is fixedly connected to the middle of the top end of the connection disk 3. The output end of the syringe body 1 is fixedly connected with a first threaded head 5, and the first threaded head 5 is threadedly connected to the first connection pipe 4. A plurality of angle adjustment members are respectively arranged at the bottom end of the connection disk 3.

[0033] The needle assembly includes a plurality of connecting members, a plurality of length adjustment members, and a plurality of needles 6. The plurality of connecting members are respectively connected to the plurality of adjustment members, and the angle of the connecting members is adjusted through the length adjustment members. The plurality of needles 6 are respectively connected to the connecting members through the length adjustment members, and the injection depth of the needles 6 is adjusted through the length adjustment members.

[0034] In one embodiment of the present invention, during use, the connection disk 3 is connected to the syringe body 1 through the first connection pipe 4 and the first threaded head 5, the needle 6 is installed on the length adjustment member, the length adjustment member is connected to the angle adjustment member through the connecting member, the angle of the needle 6 is adjusted by the provided angle adjustment member, and the injection length of the needle 6 is adjusted by the provided length adjustment member, so as to adapt to different usage situations.

[0035] As an optional implementation manner, the angle adjustment member includes a plurality of adjustment disks 7. One of the adjustment disks 7 is fixedly connected to the middle of the bottom end of the connection disk 3. A plurality of adjustment holes 8 are formed in the bottom end of the connection disk 3 along the circumferential direction. The remaining plurality of adjustment disks 7 are respectively rotatably connected in the plurality of adjustment holes 8. A conveying channel 9 is formed in the adjustment disk 7. One end of the conveying channel 9 is communicated with the connection disk 3 through a pipe 10. A plurality of limiting members are arranged on the adjustment disk 7, and the plurality of limiting members are respectively connected to the plurality of adjustment disks 7 in a limiting manner.

[0036] In an embodiment of the present invention, the adjustment disk 7 in the middle is fixed on the connection disk 3, and the adjustment disk 7 in the circumferential direction is rotatably connected in the adjustment hole 8. The angle of the needle 6 is adjusted by rotating the adjustment disk 7, and after adjustment, it is limited and connected by a limiting member.

[0037] As an alternative embodiment, a plurality of threaded holes are axially formed on the outer wall of the connection disk 3. The limiting member includes a first bolt 11 threadedly connected in the threaded hole. One end of the first bolt 11 extends out of the threaded hole and is fixedly connected with a knob 12. The other end of the first bolt 11 extends into the adjustment hole 8 and is fixedly connected with a limiting head 13. A tooth groove is formed on the outer wall of the adjustment disk 7, and the limiting head 13 is adapted to the tooth groove.

[0038] In an embodiment of the present invention, by manually turning the knob 12, the first bolt 11 is driven to move in the threaded hole, so that the limiting head 13 is engaged with the tooth groove to limit the adjustment disk 7 after the adjustment angle.

[0039] As an alternative embodiment, the connecting member includes an adjustment cylinder 14. The top end of the adjustment cylinder 14 is fixedly connected with a second threaded head 15. A second connecting pipe 16 is fixedly connected to the adjustment disk 7. The second threaded head 15 is threadedly connected with the second connecting pipe 16.

[0040] In an embodiment of the present invention, by threading the second threaded head 15 and the second connecting pipe 16, the stability of the connection is ensured.

[0041] As an alternative embodiment, the length adjustment member includes a delivery pipe 17. A slider 18 is fixedly connected to the delivery pipe 17. The delivery pipe 17 is slidably connected to the adjustment cylinder 14 through the slider 18. External threads are formed on the outer side wall of the delivery pipe 17. An adjustment ring 19 is rotatably connected to the bottom end of the adjustment cylinder 14. Internal threads are formed on the inner side wall of the adjustment ring 19. The external threads are adapted to the internal threads.

[0042] In an embodiment of the present invention, specifically, a vertical chute is formed inside the adjustment cylinder 14. The slider 18 is slidably connected in the chute, so that the delivery pipe 17 can slide vertically. By rotating the adjustment ring 19, the threaded delivery pipe 17 moves relatively vertically, thereby driving the needle 6 at the bottom end to move, and adjusting the length of the needle 6 extending out of the adjustment cylinder 14.

[0043] As an alternative embodiment, a clamping member is further included. A third connecting pipe 20 is fixedly connected to the bottom end of the delivery pipe 17. A connecting head 21 is fixedly connected to the end of the needle 6 away from the tip. The third connecting pipe 20 is inserted into the connecting head, and the clamping member is arranged on the delivery pipe 17 to clamp the connecting head 21.

[0044] In one embodiment of the present invention, the needle 6 is installed by inserting the connecting head 21 into the third connecting pipe 20. After installation, the needle 6 is clamped by the provided clamping member to ensure the stability of the needle 6.

[0045] As an alternative embodiment, the clamping member includes a plurality of clamping plates 22. One end of the plurality of clamping plates 22 is fixedly connected to the bottom end of the conveying pipe 17 in the circumferential direction. The other end of the clamping plate 22 is fixedly connected with a clamping head 23. A threaded sleeve 24 is sleeved on the clamping plate 22. When the threaded sleeve 24 is threadedly connected to the outer wall of the clamping plate 22, the clamping head 23 is in contact with the connecting head 21.

[0046] In one embodiment of the present invention, at the initial state, the bottom ends of the plurality of clamping plates 22 are in a bent state to facilitate the installation of the connecting head 21. When the threaded sleeve 24 is screwed to gradually move downward, it squeezes and contracts the lower part of the clamping plate 22, so that the clamping head 23 is connected to the connecting head 21, thereby ensuring the stability of the needle 6 during use and preventing the needle 6 from falling off.

[0047] Specifically, the clamping plate 22 is made of elastic metal material and can achieve deformation and reset.

[0048] As an alternative embodiment, a pressure release valve 25 is provided on the syringe body 1.

[0049] In one embodiment of the present invention, the provided pressure release valve 25 enables medical staff to adjust the injection pressure according to the hardness of the tumor, thereby preventing the needle from bending or breaking when penetrating the tumor.

[0050] As an alternative embodiment, both sides of the top end of the syringe body 1 are fixedly connected with handles 26, and anti-slip pads 27 are fixedly connected to the handles 26.

[0051] In one embodiment of the present invention, the provided handle 26 facilitates the application of force, and the provided anti-slip pad 27 ensures the holding stability of medical staff during use.

[0052] As an alternative embodiment, the syringe body 1 is a metal syringe, and a transparent scale window 28 is provided on the syringe body 1.

[0053] In one embodiment of the present invention, the syringe body 1 being a metal syringe ensures the overall structural strength, and the transparent scale window 28 provided on the syringe body 1 is used to observe the remaining amount of liquid medicine in the syringe body 1.

[0054] Embodiment 2:

[0055] Refer to Figure 7 , in one embodiment of the present invention, the needle 6 can be replaced with an umbrella-shaped branched needle. The main needle syringe and the umbrella-shaped branch are hollow and can both inject liquid medicine.

[0056] This syringe is equipped with an umbrella-shaped needle for local multi-point injection of larger tumors to ensure sufficient infiltration of the drug.

[0057] In the description of the present invention, it should be understood that the orientation or positional relationship indicated by the terms "longitudinal", "transverse", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be construed as a limitation on the present invention.

[0058] The above-described embodiments are only descriptions of the preferred embodiments of the present invention, and do not limit the scope of the present invention. Without departing from the design spirit of the present invention, various deformations and improvements made by those of ordinary skill in the art to the technical solutions of the present invention shall fall within the protection scope determined by the claims of the present invention.

Claims

1. A syringe for oncolytic virus, comprising a syringe body (1) and a piston (2) adapted to the syringe body (1), characterized in that: It also comprises an interface assembly, the interface assembly comprising a connection plate (3) and a plurality of angle adjustment members, a first connection tube (4) is fixedly connected to the middle of the top end of the connection plate (3), a first threaded head (5) is fixedly connected to the output end of the syringe body (1), the first threaded head (5) is threadedly connected to the first connection tube (4), and the plurality of angle adjustment members are respectively arranged at the bottom end of the connection plate (3); A needle assembly comprises a plurality of connecting members, a plurality of length adjusting members and a plurality of needles (6), wherein the plurality of connecting members are respectively connected to the plurality of adjusting members, and the angles of the connecting members are adjusted by the length adjusting members, and the plurality of needles (6) are respectively connected to the connecting members by the length adjusting members, and the injection depth of the needles (6) is adjusted by the length adjusting members.

2. The oncolytic virus-specific syringe according to claim 1, characterized in that: The angle adjustment member comprises a plurality of adjustment disks (7), wherein one of the adjustment disks (7) is fixedly connected to the middle of the bottom end of the connection disk (3), the bottom end of the connection disk (3) is provided with a plurality of adjustment holes (8) along the circumferential direction, and the remaining plurality of adjustment disks (7) are rotatably connected in the plurality of adjustment holes (8), a conveying channel (9) is provided in the adjustment disk (7), one end of the conveying channel (9) is connected to the connection disk (3) through a pipeline (10), and a plurality of limiting members are arranged on the adjustment disk (7), and the plurality of limiting members are respectively connected to the plurality of adjustment disks (7) in a limiting manner.

3. The oncolytic virus-specific syringe according to claim 2, characterized in that: A plurality of threaded holes are axially provided on the outer wall of the connection disk (3); the limiting member comprises a first bolt (11) threadedly connected in the threaded hole; one end of the first bolt (11) extends out of the threaded hole and is fixedly connected to a knob (12); the other end of the first bolt (11) extends into the adjustment hole (8) and is fixedly connected to a limiting head (13); a tooth groove is provided on the outer wall of the adjustment disk (7); the limiting head (13) is adapted to the tooth groove.

4. The oncolytic virus-specific syringe according to claim 3, characterized in that: The connecting piece comprises an adjusting tube (14), a second threaded head (15) is fixedly connected to the top end of the adjusting tube (14), a second connecting tube (16) is fixedly connected to the adjusting disk (7), and the second threaded head (15) is threadedly connected to the second connecting tube (16).

5. The oncolytic virus-specific syringe according to claim 4, characterized in that: The length adjustment member comprises a delivery tube (17), a slider (18) is fixedly connected to the delivery tube (17), the delivery tube (17) is slidably connected to the adjustment tube (14) via the slider (18), an outer wall of the delivery tube (17) is provided with an external thread, the bottom end of the adjustment tube (14) is rotatably connected with an adjustment ring (19), an inner wall of the adjustment ring (19) is provided with an internal thread, and the external thread is adapted to the internal thread.

6. The oncolytic virus-specific syringe according to claim 5, characterized in that: The invention also comprises a clamping member, wherein the bottom end of the delivery tube (17) is fixedly connected to a third connecting tube (20), the end of the needle (6) away from the tip is fixedly connected to a connecting head (21), the third connecting tube (20) is plugged into the connecting head, and the clamping member is arranged on the delivery tube (17) for clamping the connecting head (21).

7. The oncolytic virus-specific syringe according to claim 6, characterized in that: The clamping member comprises a plurality of clamping plates (22), one end of each of the clamping plates (22) being fixedly connected to the bottom end of the conveying pipe (17) along the circumferential direction, and the other end of each of the clamping plates (22) being fixedly connected to a clamping head (23), a threaded sleeve (24) being sleeved on the clamping plate (22), and when the threaded sleeve (24) is threadedly connected to the outer wall of the clamping plate (22), the clamping head (23) is arranged in contact with the connecting head (21).

8. The oncolytic virus-specific syringe according to claim 1, characterized in that: The syringe body (1) is provided with a pressure release valve (25).

9. The oncolytic virus-specific syringe according to claim 1, characterized in that: Both sides of the top end of the syringe body (1) are fixedly connected with handles (26), and anti-slip pads (27) are fixedly connected to the handles (26).

10. The oncolytic virus-specific syringe according to claim 1, characterized in that: The syringe body (1) is a metal syringe, and a transparent scale window (28) is provided on the syringe body (1).

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