System for extracting cells in organism
Through the automated design of the in vivo cell extraction system, the complexity and inefficiency of manually dissecting mice to obtain cells were solved, and efficient and accurate cell extraction and equipment cleaning were achieved.
Patent Information
- Application Number
- CN202510758815.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-06-09
- Publication Date
- 2025-09-12
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
In the existing technology, manually dissecting mice to obtain cells is complicated, inefficient, and difficult to ensure accuracy. In particular, hand shaking affects the effect when extracting a large number of cells.
An in vivo cell extraction system was designed, which includes a grid platform, a drying device, a disinfection device, an ultrasonic cleaning device, a rotating rack, a sampling rack, an expansion clamp, a clamping forceps and other components to achieve automatic fixed-point positioning cell acquisition and equipment cleaning, reducing manual operation steps.
It improves the accuracy and efficiency of cell extraction, reduces the complexity of manual operation, and ensures the cleanliness of the equipment and the accuracy of the sampling process.
Smart Images
Figure CN120616624A_ABST
Abstract
Description
Technical Field
[0001] The present invention mainly relates to the technical field of biomedical instruments, and in particular to an in vivo cell extraction system. Background Art
[0002] In the modern medical field, biological drugs are often made by using organisms as experimental specimens. This process is inseparable from the dissection of organisms to obtain cells at corresponding positions as experimental materials for analysis. In general, mice are used for experiments, but the acquisition of biological cells usually requires the experimenter to manually dissect the mice. The belly of the mouse is cut open, and then sampling operations are performed at the corresponding positions. Because the dissection process requires high precision, the process has high requirements for the operator, requiring psychological stability and precise hand movements. In addition, a large number of cells need to be extracted for each experiment. When many times of cell extraction are required, the human hand shakes more after a large amount of operation, and it cannot be guaranteed that the manual operation can accurately obtain cells every time. In addition, manual labor is limited and the operating efficiency will be reduced. Therefore, if cells need to be accurately and efficiently obtained in the body, a special cell extraction system is very necessary. Summary of the Invention
[0003] (1) Technical issues to be resolved
[0004] In view of the above-mentioned problems, the present invention needs to provide an in vivo cell extraction system. Taking mice as experimental specimens as an example, the equipment should automatically locate and complete the cell acquisition process and automatically place the cells on the table for people to take away directly. The equipment should also have its own automatic cleaning function for equipment tools, thereby reducing the work steps of the experimenter and improving work efficiency and extraction accuracy.
[0005] (2) Technical solution
[0006] In response to the above technical problems, the present invention provides an in vivo cell extraction system, comprising a base plate and a bracket, a grid platform is provided in the middle of the base plate, the bottom of the grid platform is connected to a bottom hose and communicated with a storage device, a drying device, a disinfection device and an ultrasonic cleaning device are provided on one side of the grid platform, and a cell sample storage box is detachably provided on the other side of the grid platform, a three-section rotating rack is rotatably provided on the bracket, an operating panel is movably provided at the bottom of the three-section rotating rack, a camera is provided at the bottom of the operating panel, a sampling rack is rotatably provided on the operating panel, a blade is detachably provided at one end of the sampling rack, an expansion clamp is rotatably provided at the other end of the sampling rack, a clamping claw is rotatably provided inside the expansion clamp, and blood vessels are also provided on both sides of the expansion clamp.
[0007] Furthermore, the three-section rotating frame is fixedly connected to the output shaft of the rotating motor, the rotating motor is fixedly installed on the bracket, and three groups of connecting rod assemblies are evenly arranged on the circumference of the three-section rotating frame to connect with the operating panel, and the three groups of connecting rod assemblies have the same structure.
[0008] Furthermore, the connecting rod assembly includes an adjustment motor, which is fixedly mounted on a three-section rotating frame. The output shaft of the adjustment motor is fixedly connected to the adjustment rod. The other end of the adjustment rod is rotatably connected to the double-headed first connecting rod. A connecting rod is hinged at each end of the double-headed first connecting rod. The two connecting rods are respectively hinged at the two ends of the double-headed second connecting rod. The double-headed second connecting rod is rotatably mounted on the operating panel. The adjustment motors in the three groups of connecting rod assemblies are controlled separately.
[0009] Furthermore, the operating panel is provided with two slots, one large and one small. A sampling motor is fixedly installed in the small slot. The output of the sampling motor is fixedly connected to the sampling rack. The sampling rack is rotatably set in the large slot. The blade is detachably installed on the sampling rack using screws.
[0010] Furthermore, a hemostatic container is fixedly installed on the sampling rack, one end of the vascular stop is connected to the hemostatic container, and the other end extends away from the hemostatic container to the bottom of the expansion clamp. Two vascular stop are provided, and the two vascular stop are symmetrically arranged on the center of the hemostatic container.
[0011] Furthermore, the expansion clamp includes spreading jaws arranged on both sides of the sampling rack, the spreading jaws on both sides have the same structure and are axially symmetrically arranged; the spreading jaws include a first jaw and a second jaw, the first jaw and the second jaw have the same structure, the head end of the first jaw is rotatably connected to the sampling rack, the end of the first jaw is hook-shaped, the head end of the second jaw is rotatably connected to the sampling rack, the first jaw and the second jaw are cross-rotated on the sampling rack, and the end of the first jaw is serrated; a tension spring is respectively provided on the head end of the first jaw and the second jaw and connected to the fixed axis.
[0012] Furthermore, a cross bar is used to fix the two first clamping jaws and the two second clamping jaws on both sides of the sampling rack, so as to keep the clamping jaws on both sides working simultaneously; the two cross bars are respectively located on both sides of the clamping jaws, and the clamping jaws are extended downward and over the cross bars for arrangement.
[0013] Furthermore, the clamping pliers includes a first cutting pliers and a second cutting pliers, the first cutting pliers and the second cutting pliers have the same structure and are arranged in a central symmetrical manner; the top of the first cutting pliers is provided with a cylinder, and the bottom is a shovel-shaped structure with a accommodating cavity, the top of the accommodating cavity rotates on an auxiliary shaft, and the cylinder on the top of the first cutting pliers slides in the sampling horizontal circle.
[0014] Furthermore, the sampling horizontal ring is fixedly mounted on the movable end of the sampling cylinder, the sampling cylinder is fixedly mounted on the sampling frame, the movable end of the sampling cylinder is arranged through the sampling support frame, and a sampling spring is sleeved on the movable end of the sampling cylinder; the auxiliary shaft is fixedly mounted on the sampling support frame, and the sampling support frame is fixedly mounted on the sampling frame.
[0015] The advantages of the present invention compared with the prior art are as follows: 1. The present invention is provided with a grid platform, a bottom hose, a storage device, a drying device, a disinfecting device and an ultrasonic cleaning device. The grid platform, the cell sample storage box, the grid platform, the bottom hose and the storage device are composed of a structure that can place mice and fix them, and can also handle excess blood stains to prevent them from affecting the sampling operation. The drying device, the disinfecting device and the ultrasonic cleaning device are used together to disinfect the equipment and ensure that the sampling is not contaminated; 2. The present invention is provided with a three-section rotating frame, an operating panel, a camera, three sets of connecting rod assemblies, a sampling The structure consisting of a sample frame, a blade, an expansion clamp, a clamping claw, a vascular stasis, a three-section rotating frame, an operating panel, a camera, and three sets of connecting rod components can drive the blade, the expansion clamp, the clamping claw, and the vascular stasis to move in multiple directions, adapting to the multi-directional and multi-angle needs of cutting mice and sampling on mice; 3. The expansion clamp, the clamping claw, the vascular stasis, and the blade of the present invention are used in combination to automatically dissect and cut mice, use the expansion clamp to open the belly tissue of the mouse, use the vascular stasis to absorb the infiltrated blood and tissue fluid, and then use the clamping claw to automatically obtain the cell position, completing the automatic sampling process. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] Figure 1 It is a schematic diagram of the overall structure of the present invention.
[0017] Figure 2 This is a partial first-angle schematic diagram of the extraction mechanism of the present invention.
[0018] Figure 3 This is a partial second angle schematic diagram of the extraction mechanism of the present invention.
[0019] Figure 4 It is a partial third-angle schematic diagram of the extraction mechanism of the present invention.
[0020] Figure 5 This is a schematic diagram of the camera installation position of the present invention.
[0021] Figure 6 This is a partial schematic diagram of the extraction mechanism of the present invention from the fourth angle.
[0022] Figure 7 This is a partial fifth-angle schematic diagram of the extraction mechanism of the present invention.
[0023] Figure 8 This is a partial sixth angle schematic diagram of the extraction mechanism of the present invention.
[0024] Figure 9 This is a partial schematic diagram of the seventh angle of the extraction mechanism of the present invention.
[0025] Figure 10 This is a schematic diagram of the first cutting forceps, auxiliary shaft, and second cutting forceps of the present invention.
[0026] Reference numerals: 1-extraction mechanism; 101-bottom plate; 102-bracket; 103-sash platform; 104-bottom hose; 105-storage device; 106-extraction pump; 107-drying device; 108-disinfection device; 109-ultrasonic cleaning device; 110-cell sample storage box; 111-rotating motor; 112-three-stage rotating frame; 113-adjustment motor; 114-double-headed first connecting rod; 115-adjustment rod; 116-connecting rod; 117-double-headed second connecting rod; 118 -operating panel; 119-sampling motor; 120-sampling rack; 121-screw; 122-blade; 123-camera; 124-hemostasis container; 125-hemostasis port; 126-tension spring; 127-first clamp; 128-second clamp; 129-blood vessel; 130-cross bar; 131-fixed axis; 132-sampling cylinder; 133-sampling spring; 134-sampling horizontal ring; 135-sampling support frame; 136-first knife forceps; 137-auxiliary axis; 138-second knife forceps. DETAILED DESCRIPTION
[0027] The present invention will be further described below with reference to specific embodiments. The present invention is explained through the exemplary embodiments and descriptions of the present invention, but is not intended to limit the present invention.
[0028] Example: Figures 1-10 The illustrated in vivo cell extraction system includes an extraction mechanism 1, which includes a base plate 101 and a bracket 102. The bracket 102 is fixedly mounted on the base plate 101. The base plate 101 serves as an integral base plate and can be mounted on a laboratory bench.
[0029] A grid platform 103 is provided in the middle of the bottom plate 101. The grid platform 103 is configured to place a mouse as an operating object, and the bottom can also receive impurities such as tissue fluid and blood. The grid-shaped top of the grid platform 103 can also be used with buckles to fix the operating object. The buckles need to be set according to the size of the gaps between the grids. The buckles adopt some commonly used structures in the prior art, such as U-shaped buckles. A bottom hose 104 is connected to the storage device 105 at the bottom of the grid platform 103. An extraction pump 106 is provided on the storage device 105 and is connected to the storage device 105.
[0030] A drying device 107, a disinfecting device 108, and an ultrasonic cleaning device 109 are provided on one side of the sash platform 103. The drying device 107, the disinfecting device 108, and the ultrasonic cleaning device 109 are all devices known in the prior art and are not shown in detail in the figure. They are described in text here. The disinfecting device 108 is connected to two pipes, one of which is connected to the disinfectant pipeline for introducing disinfectant, such as alcohol, iodine tincture, etc., and the other is connected to the waste water pipe for discharging waste after disinfection.
[0031] The drying device 107 can be implemented by various drying equipment in the prior art, such as an electric heating blast constant temperature drying device; the ultrasonic cleaning device 109 is also connected to the water inlet pipe and the water outlet pipe.
[0032] The drying device 107, the disinfection device 108, and the ultrasonic cleaning device 109 can be controlled by buttons or programmed for automatic use; the disinfection device 108 can be filled with disinfectant during use, and the waste liquid can be discharged after the equipment is disinfected, and then new disinfectant can be filled in again.
[0033] A cell sample storage box 110 is detachably provided on the other side of the grid platform 103. A base is provided on the bottom plate 101, and a groove is provided on the base. A clamping post is provided at the bottom of the cell sample storage box 110, and the clamping post extends into the groove of the base to achieve docking and fixation of the two. When the cell sample storage box 110 is needed, the cell sample storage box 110 can be taken out; four partition trays are provided on the cell sample storage box 110, and each partition tray is used to hold different experimental materials.
[0034] The three-section rotating frame 112 is fixedly connected to the output shaft of the rotating motor 111, and the rotating motor 111 is fixedly mounted on the bracket 102. The three-section rotating frame 112 is rotatably mounted on the bracket 102. An embedded groove can be provided on the bracket 102, and a protrusion is provided on the three-section rotating frame 112. The protrusion of the three-section rotating frame 112 is inserted into the embedded groove of the bracket 102 to support the stable rotation of the three-section rotating frame 112. Three groups of connecting rod assemblies are evenly arranged on the circumference of the three-section rotating frame 112 and are connected to the operating panel 118. A camera 123 is provided at the bottom of the operating panel 118. The camera 123 is used to display the specific situation of the operated object below. The three groups of connecting rod assemblies have the same structure.
[0035] The connecting rod assembly includes an adjustment motor 113, which is fixedly mounted on a three-section rotating frame 112. The output shaft of the adjustment motor 113 is fixedly connected to an adjustment rod 115. The other end of the adjustment rod 115 is rotatably connected to a double-headed first connecting rod 114. Each end of the double-headed first connecting rod 114 is hinged with a connecting rod 116. The two connecting rods 116 are respectively hinged at the two ends of a double-headed second connecting rod 117. The double-headed second connecting rod 117 is rotatably mounted on an operating panel 118. The adjustment motors 113 in the three groups of connecting rod assemblies are controlled separately.
[0036] The operating panel 118 is provided with two slots, one large and one small. A sampling motor 119 is fixedly installed in the small slot. The output of the sampling motor 119 is fixedly connected to the sampling rack 120. The sampling rack 120 is rotatably set in the large slot. The blade 122 is detachably installed on the sampling rack 120 using a screw 121.
[0037] A hemostatic container 124 is also fixedly mounted on the sampling rack 120. A hemostatic port 125 is provided on the hemostatic container 124. A hose is connected between the hemostatic port 125 and the extraction pump 106. The hose is not shown in the figure. One end of a vascular endothelium 129 is connected to the hemostatic container 124, and the other end extends away from the hemostatic container 124 to the bottom of the expansion clamp. Two vascular endothelium 129 are provided, and the two vascular endothelium 129 are symmetrically arranged on the center of the hemostatic container 124.
[0038] The expansion clamp includes a stretching jaw provided on both sides of the sampling rack 120, and the stretching jaws on both sides have the same structure and are axially symmetrically arranged; the stretching jaws include a first jaw 127 and a second jaw 128, and the first jaw 127 and the second jaw 128 have the same structure, the head end of the first jaw 127 is rotatably connected to the sampling rack 120, the end of the first jaw 127 is hook-shaped, and the head end of the second jaw 128 is rotatably connected to the sampling rack 120, the first jaw 127 and the second jaw 128 rotate crosswise on the sampling rack 120, and the end of the first jaw 127 is provided with a serrated structure, which is convenient for increasing friction and making it easier to stretch the operated object; a tension spring 126 is respectively provided on the head end of the first jaw 127 and the second jaw 128, which is connected to the fixed shaft 131, and the fixed shaft 131 is fixedly mounted on the sampling rack 120, and the tension spring 126 plays a role of buffering and resetting.
[0039] The two first clamping jaws 127 and the two second clamping jaws 128 on both sides of the sampling rack 120 are fixedly connected by a cross bar 130, so as to keep the clamping jaws on both sides working at the same time; the two cross bars 130 are respectively located on both sides of the clamp, and the clamp extends downward and crosses the cross bars 130 for arrangement. When the clamp is opened, the cross bars 130 are pushed first, thereby opening the first clamping jaws 127 and the second clamping jaws 128 on both sides, thereby opening the belly of the mouse. Only after opening can the clamp facilitate the grasping operation.
[0040] The clamping forceps includes a first cutting forceps 136 and a second cutting forceps 138. The first cutting forceps 136 and the second cutting forceps 138 have the same structure and are arranged in a central symmetrical manner. A cylinder is provided on the top of the first cutting forceps 136, and a shovel-shaped structure with a accommodating cavity is provided at the bottom. The edge of the shovel-shaped structure is sharp, the same as the blade, and has cutting ability. The upper part of the accommodating cavity is an arc-shaped surface, which contacts the auxiliary shaft 137 and rotates on the auxiliary shaft 137 to maintain the stability of the first cutting forceps 136 and the second cutting forceps 138. The cylinders on the top of the first cutting forceps 136 and the second cutting forceps 138 slide in the sampling horizontal circle 134.
[0041] The sampling horizontal ring 134 is fixedly mounted on the movable end of the sampling cylinder 132, and the sampling cylinder 132 is fixedly mounted on the sampling frame 120. The movable end of the sampling cylinder 132 is set through the sampling support frame 135. A sampling spring 133 is sleeved on the movable end of the sampling cylinder 132 and between it and the sampling horizontal ring 134. The sampling spring 133 plays a role of buffering and resetting. One end of the sampling spring 133 is fixedly mounted on the sampling support frame 135, and the other end is fixedly mounted on the sampling horizontal ring 134; the auxiliary shaft 137 is fixedly mounted on the sampling support frame 135, and the sampling support frame 135 is fixedly mounted on the sampling frame 120.
[0042] The present invention also needs to set up a liquid crystal operating table for users to use. The operating table is equipped with a computer control program for controlling the present invention. The present invention can be operated by buttons or switched to automatic recognition and clamping operation. Both modes are available.
[0043] The working principle of the present invention is as follows: the present invention is installed on a laboratory bench with the base plate 101 as the base. The object to be operated on, such as a mouse, whose cells need to be obtained is placed unconscious on the grid platform 103. The four feet of the mouse are clamped on the grid plate with buckles to secure it. The camera 123 is used to capture the image in real time. The blade 122 is installed on the sampling frame 120 with two screws 121. Then, the sampling motor 119 is started to drive the sampling frame 120 to rotate, and the blade 122 is rotated downward.
[0044] Then, under the action of the three adjustment motors 113, the operating disk 118 is driven to move, and the blade 122 is first placed in the disinfection device 108 for disinfection, and then placed in the drying device 107 for drying, and then moved above the mouse. This process requires separate adjustment of the three adjustment motors 113, that is, adjusting the three groups of connecting rod assemblies to work separately. The basic working principle of each group of connecting rod assemblies is the same. When the adjustment motor 113 is started, it drives the adjustment rod 115 to rotate, and the adjustment rod 115 drives the double-headed first connecting rod 114, the connecting rod 116, and the double-headed second connecting rod 117 to rotate, thereby driving the operating disk 118 to move.
[0045] Then, the position of the blade 122 is adjusted by using three adjustment motors 113 at different speeds, and the blade 122 is used to cut a wound on the mouse's belly. After the cutting is completed, the blade 122 is moved to the ultrasonic cleaning device 109 for cleaning. After the cleaning is completed, it is placed in the disinfection device 108 for disinfection. At this time, the disinfection device 108 has been re-introduced with disinfectant, and it is dried after the cleaning is completed. After this step is completed, the waste liquid is discharged and new disinfectant is re-introduced for use.
[0046] At this time, the sampling motor 119 is activated to rotate the second clamp 128 and the second forceps 138 downward, and the clamps are moved to the disinfection device 108 for disinfection and the drying device 107 for drying. Finally, the clamps 138 are moved to the location of the mouse wound. The second forceps 138 move the two blood stoppers 129 downward to contact the wound location, and remove excess blood that may affect the sampling process. The blood then flows through the hemostasis container 124 and the hose to the storage device 105. During the sampling process, the blood will drip onto the bottom of the sash platform 103 and enter the storage device 105 through the bottom hose 104 to avoid affecting the operation.
[0047] When the second clamping jaw 128 and the first clamping jaw 127 contact the wound made by the mouse, the active end of the sampling cylinder 132 is started to contract and drive the sampling horizontal circle 134 to move, and the sampling horizontal circle 134 drives the first cutting forceps 136 and the second cutting forceps 138 to rotate. When the first cutting forceps 136 and the second cutting forceps 138 rotate, they contact the cross bar 130 and push the cross bar 130, the first clamping jaw 127 and the second clamping jaw 128 on both sides to rotate, and the first clamping jaw 127 and the second clamping jaw 128 are used to open the belly of the mouse, while making it easier for the first cutting forceps 136 and the second cutting forceps 138 to enter the wound. When the position where cells need to be obtained is reached, the active end of the blade 122 is started to extend and drive the first cutting forceps 136 and the second cutting forceps 138 to close. The first cutting forceps 136 and the second cutting forceps 138 cut and obtain part of the tissue of the mouse and store it in the first cutting forceps 136 and the second cutting forceps 138.
[0048] Then start the three adjustment motors 113 again and cooperate with the rotation motor 111 to place the obtained tissue cells in the corresponding separation tray on the cell sample storage box 110, and then repeat the above operation and take samples multiple times. After all the sampling is completed, the cell sample storage box 110 can be disassembled and sent to the area where the cells are to be tested.
[0049] After all sampling is completed, the second clamp 128, the first clamp 127, the first knife forceps 136, and the second knife forceps 138 can be disinfected and dried in the above-mentioned manner. The present invention can be designed to be regularly disassembled and replaced with new second clamp 128, the first clamp 127, the first knife forceps 136, and the second knife forceps 138.
[0050] Any matters not described in the present invention are applicable to the prior art.
Claims
1. A system for extracting cells from a living organism, comprising a base plate (101) and a support (102), characterized in that: A grid platform (103) is provided in the middle of the bottom plate (101), and a bottom hose (104) is connected to the bottom of the grid platform (103) and communicated with the storage device (105). A drying device (107), a disinfection device (108) and an ultrasonic cleaning device (109) are provided on one side of the grid platform (103). A cell sample storage box (110) is detachably provided on the other side of the grid platform (103). A three-section rotating frame (112) is rotatably provided on the bracket (102), and an operating disk (118) is movably provided at the bottom of the three-section rotating frame (112). A camera (123) is provided at the bottom of the operating disk (118). A sampling rack (120) is rotatably provided on the operating disk (118), and a blade (122) is detachably provided at one end of the sampling rack (120). An expansion clamp is rotatably provided at the other end of the sampling rack (120), and a clamping claw is rotatably provided inside the expansion clamp. Blood vessels (129) are also provided on both sides of the expansion clamp.
2. The in vivo cell extraction system according to claim 1, characterized in that: The three-section rotating frame (112) is fixedly connected to the output shaft of the rotating motor (111), and the rotating motor (111) is fixedly installed on the bracket (102). Three groups of connecting rod assemblies are evenly arranged on the circumference of the three-section rotating frame (112) and connected to the operating panel (118). The three groups of connecting rod assemblies have the same structure.
3. The in vivo cell extraction system according to claim 2, characterized in that: The connecting rod assembly comprises an adjusting motor (113), which is fixedly mounted on a three-section rotating frame (112); an output shaft of the adjusting motor (113) is fixedly connected to an adjusting rod (115); the other end of the adjusting rod (115) is rotatably connected to a double-headed first connecting rod (114); two ends of the double-headed first connecting rod (114) are respectively hinged with a connecting rod (116); the two connecting rods (116) are respectively hinged to the two ends of a double-headed second connecting rod (117); and the double-headed second connecting rod (117) is rotatably mounted on an operating panel (118); and the adjusting motors (113) in the three connecting rod assemblies are respectively controlled separately.
4. The in vivo cell extraction system according to claim 3, characterized in that: The operating panel (118) is provided with two slots, one large and one small. A sampling motor (119) is fixedly installed in the small slot. The output of the sampling motor (119) is fixedly connected to the sampling rack (120). The sampling rack (120) is rotatably arranged in the large slot. A blade (122) is detachably installed on the sampling rack (120) by means of a screw (121).
5. The in vivo cell extraction system according to claim 4, characterized in that: A hemostatic container (124) is also fixedly mounted on the sampling frame (120). One end of a hemostatic blood vessel (129) is connected to the hemostatic container (124), and the other end extends away from the hemostatic container (124) to the bottom of the expansion clamp. Two hemostatic blood vessels (129) are provided, and the two hemostatic blood vessels (129) are centrally symmetrically arranged on the hemostatic container (124).
6. The in vivo cell extraction system according to claim 5, characterized in that: The expansion clamp includes a pair of opening jaws arranged on both sides of the sampling frame (120), the opening jaws on both sides have the same structure and are axially symmetrically arranged; the opening jaws include a first jaw (127) and a second jaw (128), the first jaw (127) and the second jaw (128) have the same structure, the head end of the first jaw (127) is rotatably connected to the sampling frame (120), the end of the first jaw (127) is hook-shaped, the head end of the second jaw (128) is rotatably connected to the sampling frame (120), the first jaw (127) and the second jaw (128) are cross-rotated on the sampling frame (120), the end of the first jaw (127) is serrated; a tension spring (126) is respectively provided on the head end of the first jaw (127) and the second jaw (128) and is connected to the fixed shaft (131).
7. The in vivo cell extraction system according to claim 6, characterized in that: The two first clamping jaws (127) and the two second clamping jaws (128) of the stretched clamping jaws on both sides of the sampling frame (120) are fixedly connected by a cross bar (130), thereby keeping the stretched clamping jaws on both sides working simultaneously; the two cross bars (130) are respectively located on both sides of the clamping jaws, and the clamping jaws are extended downward and cross the cross bars (130) for arrangement.
8. The in vivo cell extraction system according to claim 7, characterized in that: The clamp comprises a first cutting forceps (136) and a second cutting forceps (138). The first cutting forceps (136) and the second cutting forceps (138) have the same structure and are centrally symmetrically arranged. The top of the first cutting forceps (136) is provided with a cylinder, and the bottom is a shovel-shaped structure with a receiving cavity. The upper part of the receiving cavity rotates on an auxiliary shaft (137), and the cylinder at the top of the first cutting forceps (136) slides in a sampling horizontal circle (134).
9. The in vivo cell extraction system according to claim 8, characterized in that: The sampling horizontal ring (134) is fixedly mounted on the movable end of the sampling cylinder (132), the sampling cylinder (132) is fixedly mounted on the sampling frame (120), the movable end of the sampling cylinder (132) passes through the sampling support frame (135) for installation, and a sampling spring (133) is sleeved on the movable end of the sampling cylinder (132); the auxiliary shaft (137) is fixedly mounted on the sampling support frame (135), and the sampling support frame (135) is fixedly mounted on the sampling frame (120).