Ointment for conditioning diet and promoting growth and preparation method thereof

By preparing a paste containing a combination of Chinese herbs such as Pseudostellaria baicalensis, Atractylodes macrocephala, and Chinese yam, combined with γ-aminobutyric acid and honey and brown sugar, the poor digestion and absorption and sleep problems caused by spleen and stomach qi deficiency are solved, and the growth and development of children are promoted.

CN120695122APending Publication Date: 2025-09-26SHENZHEN PINGLE ORTHOPEDICS&TRAUMATOLOGY HOSPITAL
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Patent Information

Application Number
CN202510835277.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-06-20
Publication Date
2025-09-26

AI Technical Summary

Technical Problem

Deficiency of spleen and stomach qi leads to weakened digestive function, affecting the absorption and transformation of nutrients, which in turn affects the secretion of growth hormone, leading to delayed growth and development and sleep problems in children.

Method used

A paste is made from a combination of Chinese herbs such as Pseudostellaria baicalensis, Atractylodes macrocephala, Chinese yam, and Poria cocos, combined with γ-aminobutyric acid and honey and brown sugar. It strengthens the spleen and replenishes qi, nourishes the liver and kidneys, improves sleep, and promotes the secretion of growth hormone.

Benefits of technology

Improve children's sleep quality, enhance immunity, promote growth, increase energy, assist bone and muscle growth, and solve the problem of slow growth caused by spleen and stomach qi deficiency.

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Abstract

The invention discloses an ointment for conditioning diet and promoting growth and a preparation method thereof. The ointment comprises radix pseudostellariae, bighead atractylodes rhizome, Chinese yam, poria cocos, radix paeoniae alba, wine-processed rhizoma polygonati, radix cyathulae, scalded bone fragments, fructus lycii, radix ophiopogonis, scorched hawthorn fruit, roasted malt, medicated leaven, fructus forsythiae, ligusticum wallichii, liquorice, gamma-aminobutyric acid, honey and brown sugar. The formula is used for invigorating spleen and replenishing qi and assisting in growing high; the symptoms are dialectical as spleen and stomach qi deficiency and slow growth; the radix pseudostellariae is also called a child body and can tonify qi, promote salivation and improve the immunity of children; rhizoma Atractylodis Macrocephalae, rhizoma dioscoreae and poria cocos have the effects of tonifying spleen, calming heart and tonifying qi of spleen and stomach, are monarch drugs and have the effects of eliminating dampness, tonifying qi and nourishing yin; the radix achyranthis bidentatae, the scalded bone meal, the fructus lycii and the radix ophiopogonis are used for nourishing liver and kidney and strengthening muscles and bones as ministerial drugs, and the rhizoma drynariae can promote secretion of growth hormone and accelerate bone growth according to research; the Chinese yam and the medlar can assist in growing tall and serve as ministerial drugs together; scorched hawthorn fruit, fried malt and medicated leaven are used for tonifying spleen, promoting appetite, promoting qi circulation and helping digestion as assistants;
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Description

Technical Field

[0001] The present invention relates to the technical field of edible pastes, and in particular to a paste for regulating diet and promoting growth and a preparation method thereof. Background Art

[0002] In Traditional Chinese Medicine (TCM), the spleen and stomach are known as the "foundation of acquired constitution" and are the source of the body's Qi and blood. Spleen and stomach Qi deficiency can weaken digestive function, impairing nutrient absorption and conversion, and consequently, impacting the circulation of Qi and blood throughout the body. This deficiency can lead to insufficient Qi and blood, preventing the mind from nourishing, resulting in sleep problems such as insomnia, frequent dreams, and frequent awakenings. Symptoms such as nighttime teeth grinding and drooling are often related to spleen and stomach stagnation or indigestion. Children's growth and development depend on adequate nutrition and good physical function. Spleen and stomach Qi deficiency can directly impact growth and development. A weak spleen and stomach leads to decreased digestion and absorption, preventing the body from providing adequate nutrients, impacting bone and muscle growth. Poor sleep quality can directly impact growth hormone secretion. Growth hormone is most actively secreted during deep sleep. Sleep problems caused by spleen and stomach Qi deficiency can further impair growth hormone secretion, hindering growth. Long-term spleen and stomach Qi deficiency can lead to overall developmental delay in children, manifested by lower height and weight than peers, decreased energy, and a sallow complexion. Therefore, a paste designed to regulate diet and promote growth has been proposed. Summary of the Invention

[0003] In view of the deficiencies in the prior art, the present invention provides a paste for regulating diet and promoting growth and a preparation method thereof, which are used to solve the above problems.

[0004] In order to achieve the above object, the present invention adopts the following technical solutions:

[0005] A paste for regulating diet and promoting growth is composed of the following components in parts by weight: 20-40 parts of Pseudostellaria heterophylla, 15-30 parts of Atractylodes macrocephala, 20-40 parts of Chinese yam, 20-40 parts of Poria cocos, 20-30 parts of white peony root, 10-20 parts of Polygonatum odoratum, 12-22 parts of Cyathula capitata, 15-25 parts of scalded bone powder, 10-20 parts of wolfberry, 10-20 parts of Ophiopogon japonicus, 10-20 parts of charred hawthorn, 10-15 parts of roasted malt, 8-15 parts of Liushenqu, 5-10 parts of Forsythia suspensa, 5-10 parts of Chuanxiong, 20-30 parts of liquorice, 3-8 parts of gamma-aminobutyric acid, 5-10 parts of honey, and 5-10 parts of brown sugar.

[0006] A method for preparing a diet-regulating growth-promoting paste, the method comprising:

[0007] Step 1: respectively extract, filter and concentrate the Huangjing (Polygonatum sibiricum), Chuanxiong (Achyranthes bidentata), wolfberry fruit, Ophiopogon japonicus, roasted malt, Liushenqu (Six-spirited Qu) and Forsythia suspensa with solvents to obtain corresponding extracts.

[0008] Step 2: Clean and prepare Pseudostellariae Radix, Atractylodes Macrocephalae, Chinese yam, Poria cocos, White Peony Root, Broken Bone Powder, Scorched Hawthorn, Licorice, Chuanxiong Rhizome, and Licorice separately. Grind the Pseudostellariae Radix into fine powder for later use. Boil the rest together with Poria cocos and Licorice in water, filter, and concentrate into a clear paste.

[0009] Step 3: Mix the above extracts and the clear paste, dry under reduced pressure, grind, and pass through an 80-mesh sieve to obtain dry paste powder.

[0010] Step 4: Mix the Pseudostellariae powder and dry paste powder, add γ-aminobutyric acid, then add honey and brown sugar, stir well to make a paste.

[0011] Preferably, the temperature of the reduced pressure drying is controlled at 50°C-80°C.

[0012] Compared with the prior art, the present invention has the following beneficial effects:

[0013] 1. The present invention discloses a paste for regulating diet and promoting growth, and the preparation method thereof is used for strengthening the spleen and replenishing qi, and assisting growth. The syndrome is characterized by spleen and stomach qi deficiency and slow growth. Radix Pseudostellariae, also known as Haier Shen, replenishes qi and produces body fluid, and improves children's immunity. Atractylodes macrocephala, Chinese yam, and Poria cocos strengthen the spleen and calm the mind, replenish the qi of the spleen and stomach, and are the main medicines, drying dampness, replenishing qi, and nourishing yin. Radix Achyranthis Bidentatae, Bronzed Bone Pulp, Lycium barbarum, and Radix Ophiopogonis nourish the liver and kidney, and strengthen the tendons and bones. According to research, Rhizoma Drynariae can promote the secretion of growth hormone and accelerate bone growth. Chinese yam, Lycium barbarum, and Radix Ophiopogonis are the ministers. Wolfberry can also assist in height growth and is a ministerial medicine; scorched hawthorn, fried malt, and Liushenqu strengthen the spleen and appetite, promote qi and aid digestion as adjuvants; licorice harmonizes all the medicines and is a guiding medicine; all the medicines are used together to strengthen the spleen and replenish qi, and help height growth. γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the central nervous system. It helps maintain brain balance by regulating neuronal excitability. It participates in physiological processes such as relieving anxiety, improving sleep, and stabilizing emotions. Through dietary adjustments, it changes the body's absorption, improves sleep, and promotes growth. DETAILED DESCRIPTION

[0014] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0015] In the description of this patent, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer" and the like, indicating orientations or positional relationships based on the orientations or positional relationships shown, are intended solely to facilitate the description of the present invention and simplify the description, and are not intended to indicate or imply that the devices or components referred to must have a specific orientation, be constructed, or operate in a specific orientation. Therefore, they should not be construed as limitations on the present invention. The terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance. Furthermore, unless otherwise expressly specified or limited, the terms "mounted," "connected," and "connected" should be understood broadly, meaning, for example, fixed, detachable, or integrally connected; mechanically or electrically connected; directly or indirectly through an intermediate medium, or as internal communication between two components. A person of ordinary skill in the art will understand the specific meanings of the above terms in this patent in specific contexts.

[0016] Example 1

[0017] Take 35 parts of Pseudostellariae Radix, 25 parts of Atractylodes macrocephala, 35 parts of Chinese yam, 35 parts of Poria cocos, 35 parts of white peony root, 15 parts of Polygonatum sibiricum, 17 parts of Cyathula capitata, 20 parts of scalded bone powder, 15 parts of wolfberry fruit, 15 parts of Ophiopogon japonicus, 15 parts of charred hawthorn, 10 parts of stir-fried malt, 10 parts of Liushenqu, 8 parts of Forsythia suspensa, 8 parts of Chuanxiong, 25 parts of Licorice root, 6 parts of γ-aminobutyric acid, 8 parts of honey, and 8 parts of brown sugar.

[0018] Weigh the above components according to the amount, and the specific preparation steps are as follows:

[0019] Step 1: Place Huangjing (Symph. odoratum), Chuanxiong (Achyranthes bidentata), wolfberry, Ophiopogon japonicus, roasted malt, Liushenqu (Spleen Fungus) and Forsythia suspensa (Suspensa forsythia) in a solvent respectively. Select a suitable solvent according to the properties of the Chinese medicinal materials and the solubility of the active ingredients. Commonly used solvents include water, ethanol, methanol, acetone, etc. For example, for water-soluble components, water can be selected as the solvent; for fat-soluble components, ethanol or methanol can be selected. Wash and dry the above Chinese medicinal materials, and then grind them into coarse powder to increase the contact area between the medicinal materials and the solvent and improve the extraction efficiency. Put the crushed Chinese medicinal materials into an extraction container, add an appropriate amount of solvent to completely immerse the medicinal materials. According to needs, cold soaking, hot reflux or ultrasonic-assisted extraction can be used. The cold soaking method is to soak the medicinal materials and solvent at room temperature for a certain period of time (usually 12-24 hours); the hot reflux method is to heat the medicinal materials and solvent to boiling and keep them in the reflux state for a certain period of time (usually 1-3 hours); the ultrasonic-assisted extraction method is to place the medicinal materials and solvent in an ultrasonic extractor and ultrasonically treat them for a certain period of time (usually 15-30 minutes). After the extraction is completed, let it stand for a period of time to clarify the extract.

[0020] Select the appropriate filter material based on the properties and impurity content of the extract. Common filter materials include filter paper, gauze, and microporous filter membranes. Pour the extract into a filtration device and filter it using gravity filtration or vacuum filtration. Gravity filtration uses gravity to force the extract through the filter material; vacuum filtration uses a vacuum pump to reduce the pressure within the filtration device, accelerating the filtration process. After filtration, collect the clarified extract. If a small amount of impurities remains in the extract, repeat the filtration process until the extract is clear and transparent. Select the appropriate concentration method based on the properties of the extract and the concentration requirements. Common concentration methods include vacuum concentration, atmospheric pressure concentration, and freeze drying.

[0021] Step 2: Clean and prepare Pseudostellariae Radix, Atractylodes Macrocephalae, Chinese yam, Poria cocos, White Peony Root, Broken Bone Powder, Scorched Hawthorn, Licorice, Chuanxiong Rhizome, and Licorice separately. Grind the Pseudostellariae Radix into fine powder for later use. Boil the rest together with Poria cocos and Licorice in water, filter, and concentrate into a clear paste.

[0022] Before decoction, clean the Chinese medicinal materials, remove impurities, cut into small pieces or crush into coarse powder as needed, put the processed medicinal materials into the decoction container, add appropriate amount of water (usually 8-10 times the amount of the medicinal materials), soak for no less than 2 hours, boil the soaked medicinal materials over high heat, then simmer over low heat for 1.5-2 hours. Stir constantly during the decoction process to prevent the medicinal materials from sticking to the pot. After decoction is completed, filter the medicinal liquid, add water to the medicinal residue and decoct for the second time. The second decoction time is usually 1 hour, and the medicinal materials from the two decoctions are combined. Liquid, let it stand and settle for 6-12 hours, filter the liquid after standing with a sieve (24-40 mesh) to remove the residue and large particles of impurities, filter the liquid after preliminary filtration with an 80-100 mesh sieve again to ensure that the liquid is clear, put the filtered liquid into a clean copper pot or other suitable container, first heat it to boiling over high heat, skim off the foam, when the liquid becomes concentrated, switch to low heat, keep it in a slightly boiling state, stir constantly to prevent the liquid from sticking to the pot or caking, when the liquid is concentrated to the point where it does not disperse when dripped on paper, stop heating, and the result is a clear paste.

[0023] Step 3: Mix the above extracts and the clear paste, dry under reduced pressure, grind, and pass through an 80-mesh sieve to obtain dry paste powder.

[0024] Step 4: Mix the Pseudostellariae powder and dry paste powder, add γ-aminobutyric acid, then add honey and brown sugar, stir well to make a paste.

[0025] Example 2

[0026] Take 30 parts of Pseudostellariae Radix, 20 parts of Atractylodes macrocephala, 30 parts of Chinese yam, 30 parts of Poria cocos, 30 parts of white peony root, 10 parts of Polygonatum odoratum, 12 parts of Cyathula capitata, 25 parts of scalded bone powder, 10 parts of wolfberry, 10 parts of Ophiopogon japonicus, 10 parts of charred hawthorn, 5 parts of stir-fried malt, 5 parts of Liushenqu, 4 parts of Forsythia suspensa, 4 parts of Chuanxiong, 20 parts of Licorice, 3 parts of γ-aminobutyric acid, 4 parts of honey, and 4 parts of brown sugar.

[0027] Step 4: Put the clear paste into a drying box, place it in a microwave vacuum dryer, set the vacuum degree to 0.08Mpa, the drying temperature to 75℃, and the drying time to 2 hours.

[0028] Step 4: At a temperature of 70°C, mix the Pseudostellariae powder and dry paste powder, add γ-aminobutyric acid, then add honey and brown sugar, stir well to make a paste.

[0029] The remaining steps are completed according to the steps of Example 1.

[0030] Example 3

[0031] Take 20 parts of Pseudostellariae Radix, 15 parts of Atractylodes macrocephala, 20 parts of Chinese yam, 20 parts of Poria cocos, 20 parts of white peony root, 7 parts of Polygonatum odoratum, 9 parts of Cyathula capitata, 10 parts of scalded bone powder, 6 parts of wolfberry, 6 parts of Ophiopogon japonicus, 6 parts of charred hawthorn, 4 parts of stir-fried malt, 4 parts of Liushenqu, 3 parts of Forsythia suspensa, 3 parts of Chuanxiong, 16 parts of Licorice root, 2 parts of γ-aminobutyric acid, 3 parts of honey, and 3 parts of brown sugar.

[0032] Step 4: Put the clear paste into a drying box, place it in a microwave vacuum dryer, set the vacuum degree to 0.06Mpa, the drying temperature to 65℃, and the drying time to 1.5 hours.

[0033] Step 4: At a temperature of 60°C, mix the Pseudostellariae powder and dry paste powder, add γ-aminobutyric acid, then add honey and brown sugar, stir well to make a paste.

[0034] The remaining steps are completed according to the steps of Example 1.

[0035] Example 4

[0036] Take 17 parts of Pseudostellariae Radix, 13 parts of Atractylodes macrocephala, 16 parts of Chinese yam, 17 parts of Poria cocos, 17 parts of white peony root, 5 parts of Polygonatum odoratum, 7 parts of Cyathula capitata, 7 parts of scalded bone powder, 5 parts of Lycium barbarum, 5 parts of Ophiopogon japonicus, 5 parts of charred Crataegus pinnatifida, 4 parts of stir-fried malt, 4 parts of Liushenqu, 2 parts of Forsythia suspensa, 2 parts of Chuanxiong, 13 parts of Licorice root, 1 part of γ-aminobutyric acid, 2 parts of honey, and 2 parts of brown sugar.

[0037] Step 4: Put the clear paste into a drying box, place it in a microwave vacuum dryer, set the vacuum degree to 0.04Mpa, the drying temperature to 55°C, and the drying time to 1.2 hours.

[0038] Step 4: At a temperature of 50°C, mix the Pseudostellariae powder and dry paste powder, add γ-aminobutyric acid, then add honey and brown sugar, stir well to make a paste.

[0039] The remaining steps are completed according to the steps of Example 1.

[0040] This prescription is a combination of Sijunzi Decoction and Baohe Pills. It is a classic prescription with a long history of use, and its safety and efficacy have been tested in practice. This prescription is based on TCM's theory of syndrome differentiation and treatment, and the prescriptions and medicines are selected according to the law, so it is reasonable in use. This prescription is decocted into a paste with a storage time of 3 months. The medicines in the prescription are combined as monarch, minister, adjuvant and guiding drugs. One medicine has multiple effects, and the effects of the drugs are synergistic. After patients with spleen and stomach qi deficiency and slow growth consume it, their sleep is greatly improved and their energy is relatively strong. Adverse reactions include diarrhea, nausea, diarrhea and other gastrointestinal symptoms, which can improve after stopping the drug. Please note that it is prohibited for pregnant women and infants.

[0041] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus.

[0042] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A paste for regulating diet and promoting growth, characterized in that: The invention is composed of the following components by weight: 20-40 parts of Pseudostellariae Radix, 15-30 parts of Atractylodes macrocephala, 20-40 parts of Chinese yam, 20-40 parts of Poria cocos, 20-30 parts of white peony root, 10-20 parts of Polygonatum odoratum, 12-22 parts of Cyathula capitata, 15-25 parts of scalded bone powder, 10-20 parts of wolfberry, 10-20 parts of Ophiopogon japonicus, 10-20 parts of charred hawthorn, 10-15 parts of roasted malt, 8-15 parts of Liushenqu, 5-10 parts of Forsythia suspensa, 5-10 parts of Chuanxiong, 20-30 parts of liquorice, 3-8 parts of gamma-aminobutyric acid, 5-10 parts of honey and 5-10 parts of brown sugar.

2. A method for preparing a diet-regulating growth-promoting paste according to claim 1, the method comprising: Step 1: respectively extract, filter and concentrate the Huangjing (Polygonatum sibiricum), Chuanxiong (Achyranthes bidentata), wolfberry fruit, Ophiopogon japonicus, roasted malt, Liushenqu (Six-spirited Qu) and Forsythia suspensa with solvents to obtain corresponding extracts. Step 2: Clean and prepare Pseudostellariae Radix, Atractylodes Macrocephalae, Chinese yam, Poria cocos, White Peony Root, Broken Bone Powder, Scorched Hawthorn, Licorice, Chuanxiong Rhizome, and Licorice separately. Grind the Pseudostellariae Radix into fine powder for later use. Boil the rest together with Poria cocos and Licorice in water, filter, and concentrate into a clear paste. Step 3: Mix the above extracts and the clear paste, dry under reduced pressure, grind, and pass through an 80-mesh sieve to obtain dry paste powder. Step 4: Mix the Pseudostellariae powder and dry paste powder, add γ-aminobutyric acid, then add honey and brown sugar, stir well to make a paste.

3. A diet-regulating growth-promoting ointment and preparation method according to claim 2, characterized in that: The temperature of the reduced pressure drying is controlled at 50°C-80°C.