Reagent blending processor for medical immunoassay

Abstract

The invention provides a reagent mixing processor for medical immunoassay, which comprises a workbench and a driving unit, and the driving unit drives a bearing shell to swing in a circular track in the horizontal direction; the bearing shell is located at the top of the workbench and is in lap joint with an annular bearing plate at the top of the workbench shell, the bearing plate is used for supporting the bearing shell, and the driving unit does not play a supporting role; the fixing assemblies are used for fixing reagent containers, the number of the fixing assemblies is multiple, and the multiple fixing assemblies are evenly distributed on the bearing shell; the fixing assembly is clamped in the middle or the upper middle portion of the container, and along with swinging of the bearing shell, the container swings in a circle drawing shape with the clamping point as the circle center, and the bottom of the container swings in a circle drawing mode. According to the device, the bearing shell is driven to swing in a circular track, so that the bottom of the container is circumferentially shaken, the action of manually and gently rotating and swinging a test tube is simulated, and efficient and mild uniform mixing is realized under the condition that high-speed stirring or magneton assistance is not needed.

Description

Technical Field

[0001] The invention relates to the field of immunoassays, in particular to a reagent mixing processor for medical immunoassays. Background Art

[0002] In medical experiments, immunoassays, molecular biology testing, and other fields, thorough mixing of reagents and samples is a key step in ensuring the accuracy and stability of the reaction system. Existing mixing devices mainly include vortex mixers and vertical oscillators.

[0003] Vortex mixers use a high-frequency, high-speed rotating vibrator to contact the bottom of the container, causing violent agitation of the liquid for rapid mixing. Vertical oscillation mixers use the linear reciprocating motion of the container to vibrate and agitate the liquid. While these structures can achieve a certain degree of mixing in a short period of time, they also have the following significant shortcomings:

[0004] The mixing process is violent and uncontrollable, which can easily introduce a large number of bubbles, especially when dealing with high-protein, highly sensitive enzymes or colloid samples, which can easily lead to inactivation of bioactive substances or reaction errors;

[0005] It is difficult to simulate the standard mixing action of "gentle swirling" in artificial experiments, resulting in poor results in some reaction systems that require gentle disturbance (such as immune binding).

[0006] Therefore, in order to solve the above problems, a reagent mixing processor for medical immunoassay is provided. Summary of the Invention

[0007] In order to solve the problems of existing mixing devices, such as violent and uncontrollable mixing, difficulty in simulating gentle manual rotating movements, easy generation of bubbles and inactivation of active substances, and difficulty in meeting the experimental requirements of immunoassays with high requirements for gentle mixing, the present invention provides a reagent mixing processor for medical immunoassays.

[0008] The present invention solves the above technical problems through the following technical solutions:

[0009] The present invention provides a reagent mixing processor for medical immunoassay, comprising a workbench, wherein a driving unit is provided inside the workbench, the driving unit passes through the top side wall of the workbench housing and is in eccentric transmission connection with a carrying shell;

[0010] The driving unit drives the carrying shell to swing in a circular trajectory in the horizontal direction;

[0011] The bearing shell is located on the top of the workbench and overlaps with the annular bearing plate on the top of the workbench shell. The bearing plate is used to support the bearing shell, and the driving unit does not bear any supporting role.

[0012] A fixing assembly for fixing the reagent container, wherein the fixing assembly is provided in a plurality and the fixing assembly is evenly distributed on the carrying shell;

[0013] The fixing assembly is clamped at the middle or upper middle part of the container, and as the carrying shell swings, the bottom of the container swings in a circle with the clamping point as the center.

[0014] A control panel is provided on the workbench, which is used to control the start and speed of the drive motor, etc. The connection method between the control panel and the drive motor and the power supply method of the drive motor are all existing technologies and will not be repeated in this technical solution.

[0015] As for the models of driving motor and control panel, you can select the models commonly used in mixing equipment.

[0016] In this technical solution, the driving unit includes a driving motor, the output end of the driving motor is arranged upward, and a driving shaft in a "Z" shape is fixed to the output end of the driving motor;

[0017] The top of the drive shaft passes through the through slot on the top of the workbench shell and the inner ring of the carrying ring in sequence, and is fixedly connected to the circular connecting block at the bottom of the carrying shell. The connecting block is located in the inner ring cavity of the carrying ring.

[0018] The connecting block is fixed at a biased position on the bottom of the bearing shell, and the driving motor is fixed to the side wall of the bottom of the inner cavity of the workbench through an "L"-shaped connecting piece.

[0019] The driving motor drives the bearing shell to swing in a circular trajectory through the driving shaft.

[0020] In this technical solution, the fixing assembly includes a mounting shell, and a clamping portion for clamping and fixing the container is provided above the inner cavity of the mounting shell;

[0021] The clamping portion includes an outer supporting unit and an inner clamping unit, and the inner clamping unit clamps and fixes the container;

[0022] The inner clamping unit is sleeved inside the outer supporting unit and rotates inside the outer supporting unit, and the outer supporting unit is fixed on the mounting shell.

[0023] Specifically, the inner clamping unit clamps the container, and the inner clamping unit can rotate inside the outer supporting unit, thereby providing a structural basis for the swing of the container.

[0024] In the present technical solution, the outer surface of the inner clamping unit and the outward extension surface of the outer surface constitute a complete spherical structure, and the inner cavity surface of the outer supporting unit and the outward extension surface of the inner cavity surface constitute a complete spherical structure, that is, the contact surface between the inner holding unit and the outer supporting unit is a spherical structure, and a universal rotating connection structure is formed between the inner holding unit and the outer supporting unit, so that the clamping part clamps the container and swings in the horizontal direction.

[0025] In this technical solution, the outer supporting unit includes a plurality of limiting outer covers distributed in a circular array, and two adjacent limiting outer covers are connected to each other by connecting arc rods, wherein support rods are fixed to the outer walls of at least two limiting outer covers, and the support rods are fixed to the inner wall of the mounting shell;

[0026] The inner walls of all the limiting outer covers together form a spherical structure, and the limiting outer covers are fitted on the outer walls of the inner clamping units.

[0027] The inner clamping unit rotates inside the spherical cavity surrounded by all the limiting outer covers.

[0028] In this technical solution, the inner clamping unit includes a self-rotating shell with an overall annular structure and a spherical outer wall, and the outer wall of the self-rotating shell is in contact with the inner wall of the limiting outer cover;

[0029] The clamping member is arranged in the inner cavity of the self-rotating shell, the clamping member is clamped on the surface of the container, and the container passes through the self-rotating shell.

[0030] The clamping member clamps the container, and the clamping member rotates along with the rotating shell inside the spherical cavity surrounded by the limiting outer cover.

[0031] In this technical solution, the clamping member includes two symmetrically arranged clamping arc plates, and the clamping arc plates are connected to the inner wall of the rotation shell through a first telescopic rod arranged in the horizontal direction;

[0032] A first spring is sleeved on the surface of the first telescopic rod, and the container is clamped by the elastic force provided by the first spring.

[0033] Specifically, a container containing reagents and samples is inserted between the two clamping arc plates, and the two clamping arc plates are squeezed outward so that the clamping arc plates are clamped in the middle or upper middle part of the container. At this time, the first spring is deformed, and the elastic force generated by the potential energy of the first spring to recover the deformation clamps the container.

[0034] A clamping layer made of soft rubber can be bonded to the clamping arc plate to increase the static friction between the clamping arc plate and the container.

[0035] During mixing, if necessary, a corresponding stopper can be plugged at the entrance of the container.

[0036] The counterweight part is arranged below the clamping part, and the counterweight part comprises two symmetrical "L"-shaped synchronous rods, vertical parts of the two synchronous rods are arranged along two sides of the container to be clamped, and the vertical parts extend to the bottom of the container, horizontal parts of the two synchronous rods are arranged at the bottom of the container and are connected to top ends of counterweight blocks, and the counterweight blocks are arranged directly below the two clamping arc plates.

[0037] The top of the synchronous rod is fixed on the telescopic end of the first telescopic rod.

[0038] The horizontal part of the synchronous rod is telescopic, that is, the horizontal part of the synchronous rod and the first telescopic rod are telescopic synchronously.

[0039] The counterweight blocks can reduce the gravity center of the fixed part and increase the gravity weight of the bottom of the container, so that the clamping part can better follow the bearing shell and follow the clamping of the container.

[0040] The two symmetrical auxiliary fixing units are arranged on two sides of the two synchronous rods.

[0041] The auxiliary fixing unit comprises a driving member and an auxiliary member for clamping the container, the driving member is arranged on the telescopic area of the vertical part of the synchronous rod, and the driving member pushes the auxiliary member to clamp the surface of the container along with the extension of the telescopic area of the vertical part of the synchronous rod.

[0042] The telescopic area of the vertical part of the synchronous rod is a second telescopic rod arranged in the vertical direction, and the second telescopic rod replaces the middle area of the original vertical part of the synchronous rod.

[0043] The driving member is a self-rotating transmission roller, the transmission roller is installed at the bottom end of the second telescopic rod, and the downward moving transmission roller is in transmission connection with the auxiliary member.

[0044] The auxiliary member comprises a transmission block, the top of the transmission block is provided with a transmission inclined surface, the transmission inclined surface is lapped with the transmission roller, and the transmission block is slidable in the horizontal direction.

[0045] The transmission block is fixed with an auxiliary clamping plate for clamping the container, and the auxiliary clamping plate and the transmission inclined surface are arranged on two sides of the transmission block.

[0046] The two sides of the transmission block are provided with connecting parts, the connecting parts comprise "L"-shaped fixing rods, the top of the fixing rod is fixed with a sliding block, the sliding block is slidingly connected to a horizontal guide rail arranged in the horizontal direction, the horizontal guide rail is arranged in parallel with the first telescopic rod, the top of the horizontal guide rail is connected to the telescopic end of the first telescopic rod through a connecting vertical rod, and the connecting vertical rod is arranged on the inner side of the second telescopic rod.

[0047] The surface of the second telescopic rod is sleeved with a second spring, the length of the second telescopic rod is kept by the second spring, and no additional potential energy support is provided.

[0048] One end of the third spring is connected to the sliding block, and the other end of the third spring is fixed on the guide rail, and the third spring assists in clamping the arc plate on the surface of the container in the normal state.

[0049] The top and bottom of the second telescopic rod are connected through the connecting rods and synchronous rods in the "Z" shape structure, so that the spacing between the second telescopic rod and the connecting vertical rod is increased, and the transmission block is facilitated to be arranged.

[0050] When the second spring is in the normal state, the third spring does not deform.

[0051] On the basis of common sense in the art, the above-mentioned preferred conditions can be combined arbitrarily, that is, the preferred examples of the present application are obtained.

[0052] The positive progress effect of the present application is that:

[0053] The device drives the bearing shell located thereon to swing along a circular trajectory in the horizontal direction, further drives the fixed component connected to the bearing shell to swing synchronously, so that the circumferential shaking of the bottom of the clamped container (such as a test tube, a sample tube, etc.) is realized. The circumferential shaking structure simulates the gentle rotary shaking trajectory of the middle part of the test tube held by hand, and can efficiently and gently mix the reagent and the sample in the container without relying on high-speed vortex stirring or magnetic stirring.

[0054] Compared with the traditional vortex mixer or up-down shaking type mixing structure, the device has the following beneficial effects:

[0055] High mixing uniformity, avoiding local reaction deficiency

[0056] Through the circumferential trajectory movement of the container bottom, the reagent and the sample form continuous disturbance and annular flow in the entire liquid space, effectively breaking the mixing layer difference between the liquid surface and the bottom, and improving the consistency of the reaction system and the stability of the detection result.

[0057] Avoiding bubbles and activity loss caused by violent stirring

[0058] There is no strong impact and no intermittent shock in the mixing process, which effectively avoids the generation of bubbles and the destruction of the structure of active substances such as proteins and enzymes caused by traditional high-speed vortex mixing, and is especially suitable for antibody, antigen, colloidal gold, magnetic bead and other immune reagent systems sensitive to mechanical disturbance.

[0059] Simulate the trajectory of manual operation, and have bionic mixing characteristics

[0060] The circular swinging structure simulates the classic experimental action of "holding the middle of the test tube and gently rotating it", giving the device a natural and gentle human-machine process logic, and has strong adaptability and reliability in scenarios where automation replaces manual operation.

[0061] Simple structure, low power consumption, suitable for multi-scenario integration

[0062] There is no need for auxiliary devices such as magnetic stirrers or heating platforms. The overall structure is compact and easy to control. It can be integrated as a module into small and medium-sized automated equipment such as immunoassay analyzers, PCR loading systems, and rapid detection platforms.

[0063] Reduce human operation errors and improve experimental consistency and efficiency

[0064] The fixed shaking trajectory and parameter settings standardize the mixing action between different batches and different operators, effectively improving experimental repeatability and data comparability, and are particularly suitable for high-throughput or continuous sample processing. BRIEF DESCRIPTION OF THE DRAWINGS

[0065] Figure 1 It is a schematic diagram of the overall external three-dimensional structure of the present invention;

[0066] Figure 2 For the present invention Figure 1 Schematic diagram of the top view structure;

[0067] Figure 3 For the present invention Figure 2 Schematic diagram of the cross-sectional structure at AA;

[0068] Figure 4 For the present invention Figure 2 Schematic diagram of the cross-sectional structure at BB;

[0069] Figure 5 Schematic diagram of the external three-dimensional structure of the fixing assembly of the present invention;

[0070] Figure 6 For the present invention Figure 5 Schematic diagram of the top view structure;

[0071] Figure 7 For the present invention Figure 6 Schematic diagram of the cross-sectional structure at CC;

[0072] Figure 8 This is a schematic structural diagram of the connection state of the clamping portion and the container of the present invention;

[0073] Figure 9 For the present invention Figure 8 Schematic diagram of the top view structure;

[0074] Figure 10 For the present invention Figure 9Fig. 2 is a schematic view of a cross-sectional structure of the D-D of Fig. 1;

[0075] Figure 11 Fig. 3 is a schematic view of a structure of a clamping portion of the present application;

[0076] Figure 12 Fig. 4 is a schematic view of a vertical cross-sectional structure of the clamping portion of the present application;

[0077] Figure 13 Fig. 5 is an exploded schematic view of an outer supporting unit and an inner clamping unit of the present application;

[0078] Figure 14 Fig. 6 is a schematic view of a structure of a fixing assembly with an auxiliary fixing unit of the present application;

[0079] Figure 15 Fig. 7 is a schematic view of a positional relationship structure of the auxiliary fixing unit and the fixing assembly of the present application;

[0080] Figure 16 Fig. 8 is a schematic view of a structure of the present application Figure 15 Fig. 9 is a schematic view of a positional relationship structure of the auxiliary fixing unit and the fixing assembly without a container of the present application;

[0081] Figure 17 Fig. 10 is a schematic view of a structure of the present application Figure 16 Fig. 11 is a schematic view of a structure of the present application from a top perspective;

[0082] Figure 18 Fig. 12 is a schematic view of a structure of the present application from a front perspective; Figure 16

[0083] Fig. 13 is a schematic view of a structure of the present application from a side perspective; Figure 19 Figure 16 Fig. 14 is a schematic view of a structure of the present application from a partial enlarged view of I;

[0084] Figure 20 Fig. 15 is a schematic view of a structure of the present application from a partial enlarged view of J; Figure 17

[0085] Fig. 16 is a schematic view of a structure of the present application from a partial enlarged view of K; Figure 21 Figure 18 Fig. 17 is a schematic view of a structure of the present application from a partial enlarged view of L.

[0086] BRIEF DESCRIPTION OF THE DRAWINGS

[0087] 1, workbench; 11, control panel; 12, bearing plate; 13, through slot;

[0088] 2, bearing shell;

[0089] 3, driving assembly; 31, driving motor; 32, driving shaft; 33, connecting block;

[0090] 4, fixing assembly; 41, mounting shell;

[0091] ​​5. Fixing part; 51. Position limiting cover; 52. Connecting arc rod; 53. Support rod; 54. Rotating shell; 55. First telescopic rod; 56. Clamping arc plate;

[0092] 6. Counterweight; 61. Synchronous rod; 62. Counterweight block; 63. Positioning member; 64. Second telescopic rod; 65. Connecting rod;

[0093] 7. Auxiliary fixing unit; 71. Transmission block; 72. Fixing rod; 73. Slider; 74. Horizontal guide rail; 75. Connecting vertical rod; 76. Auxiliary clamping plate; 77. Transmission roller;

[0094] 8. Container. DETAILED DESCRIPTION

[0095] The present invention is further described below by way of examples, but the present invention is not limited to the scope of the examples.

[0096] like Figure 1 and Figure 2 As shown, a reagent mixing processor for medical immunoassay includes a workbench 1, wherein a driving unit is provided inside the workbench 1, and the driving unit passes through the top side wall of the workbench 1 shell and is in eccentric transmission connection with the carrying shell 2;

[0097] The driving unit drives the carrying shell 2 to swing in a circular trajectory in the horizontal direction;

[0098] The carrying shell 2 is located on the top of the workbench 1 and overlaps with the annular carrying plate 12 on the top of the shell of the workbench 1. The carrying plate 12 is used to support the carrying shell 2, and the driving unit does not bear any supporting role.

[0099] A fixing assembly 4 for fixing the reagent container 8, wherein the fixing assembly 4 is provided in a plurality and the fixing assembly 4 is evenly distributed on the carrying shell 2;

[0100] The fixing assembly 4 is clamped at the middle or upper middle portion of the container 8 , and as the carrying shell 2 swings, the bottom of the container 8 swings in a circle with the clamping point as the center.

[0101] A control panel 11 is provided on the workbench 1, which is used to control the start and speed of the drive motor 31, etc. The connection method between the control panel 11 and the drive motor 31 and the power supply method of the drive motor 31 are all existing technologies and will not be repeated in this technical solution.

[0102] The models of the driving motor 31 and the control panel 11 can be selected from the models commonly used in mixing equipment.

[0103] The driving unit drives the carrying shell 2 to swing in a circular trajectory in the horizontal direction, thereby driving the container 8 clamped by the fixing component 4 to swing, and its bottom swings in a circular shape, so that the reagents and samples can be mixed without long-term stirring.

[0104] Example 1

[0105] like Figure 3 and 4 As shown, the driving unit includes a driving motor 31, the output end of the driving motor 31 is arranged upward, and a driving shaft 32 in a "Z" shape is fixed to the output end of the driving motor 31;

[0106] The top of the drive shaft 32 passes through the through slot 13 on the top of the workbench 1 shell and the inner ring of the carrying ring in sequence, and is fixedly connected to the circular connecting block 33 at the bottom of the carrying shell 2. The connecting block 33 is located in the inner ring cavity of the carrying ring.

[0107] The connecting block 33 is fixed at a deflected position on the bottom of the carrying shell 2 , and the driving motor 31 is fixed to the side wall of the bottom of the inner cavity of the workbench 1 through an “L”-shaped connecting piece.

[0108] The driving motor 31 drives the supporting shell 2 to swing in a circular trajectory via the driving shaft 32 .

[0109] Example 2

[0110] like Figure 5-13 As shown, the fixing assembly 4 includes a mounting shell 41, and a clamping portion for clamping and fixing the container 8 is provided above the inner cavity of the mounting shell 41;

[0111] The clamping portion includes an outer supporting unit and an inner clamping unit, and the inner clamping unit clamps and fixes the container 8;

[0112] The inner clamping unit is sleeved inside the outer supporting unit, and the inner clamping unit is sleeved inside the outer supporting unit and rotates. The outer supporting unit is fixed on the mounting shell 41.

[0113] The inner clamping unit clamps the container 8 and can rotate inside the outer supporting unit, thereby providing a structural basis for the swing of the container 8.

[0114] Furthermore, the outer surface of the inner clamping unit and the outward extension surface of the outer surface constitute a complete spherical structure, and the inner cavity surface of the outer supporting unit and the outward extension surface of the inner cavity surface constitute a complete spherical structure, that is, the contact surface between the inner holding unit and the outer supporting unit is a spherical structure, and a universal rotating connection structure is formed between the inner holding unit and the outer supporting unit, so that the clamping part clamps the container 8 and swings in the horizontal direction.

[0115] The outer support unit includes a plurality of limiting outer covers 51 distributed in an annular array. Adjacent limiting outer covers 51 are connected to each other by connecting arc rods 52. Support rods 53 are fixed to the outer walls of at least two limiting outer covers 51. The support rods 53 are fixed to the inner wall of the mounting shell 41.

[0116] The inner walls of all the limiting outer covers 51 together form a spherical structure, and the limiting outer covers 51 are fitted on the outer wall of the inner clamping unit.

[0117] The inner clamping unit rotates inside the spherical cavity surrounded by all the limiting outer covers 51.

[0118] Specifically, the inner clamping unit includes a self-rotating shell 54 with an overall annular structure and a spherical outer wall. The outer wall of the self-rotating shell 54 is in contact with the inner wall of the limiting outer cover 51.

[0119] The clamping member is arranged in the inner cavity of the rotation shell 54 , the clamping member is clamped on the surface of the container 8 , and the container 8 passes through the rotation shell 54 .

[0120] The clamping member clamps the container 8 , and the clamping member rotates along with the rotation shell 54 inside the spherical cavity surrounded by the limiting outer cover 51 .

[0121] Specifically, the clamping member includes two symmetrically arranged clamping arc plates 56, and the clamping arc plates 56 are connected to the inner wall of the rotation shell 54 through a first telescopic rod 55 arranged in the horizontal direction;

[0122] The connecting line of the two first telescopic rods 55 passes through the center of the rotating shell 54 and the center point between the two clamping arc plates 56;

[0123] A first spring is sleeved on the surface of the first telescopic rod 55 , and the container 8 is clamped by the elastic force provided by the first spring.

[0124] Insert the container 8 containing reagents and samples between the two clamping arc plates 56, and the two clamping arc plates 56 are squeezed outward so that the clamping arc plates 56 are clamped in the middle or upper middle part of the container 8. At this time, the first spring is deformed, and the elastic force generated by the potential energy of the first spring to recover the deformation clamps the container 8.

[0125] A clamping layer made of soft rubber can be bonded to the clamping arc plate 56 to increase the static friction between the clamping arc plate 56 and the container 8.

[0126] During mixing, if necessary, a corresponding stopper may be plugged at the inlet of the container 8 .

[0127] When the carrying shell 2 swings, the rotating shell 54 holding the container 8 moves and rotates in the inner cavity of the limiting outer cover 51. Since it is clamped in the middle or upper middle part of the container 8, the bottom of the container 8 swings in a circle.

[0128] An optimized technical solution in the present application also includes a counterweight portion 6 that facilitates the follow-up movement of the clamping portion. The counterweight portion 6 includes two symmetrically arranged "L"-shaped synchronization rods 61, such as Figure 10 As shown, the vertical portions of the two synchronization rods 61 are distributed along both sides of the clamped container 8, and the vertical portions extend to the bottom of the container 8. The horizontal portions of the two synchronization rods 61 are located at the bottom of the container 8 and are both connected to the top of the counterweight 62, which is located directly below the two clamping arc plates 56.

[0129] The top of the synchronization rod 61 is fixed to the telescopic end of the first telescopic rod 55;

[0130] Furthermore, the horizontal portion of the synchronization rod 61 is telescopic, that is, the horizontal portion of the synchronization rod 61 and the first telescopic rod 55 are telescopic synchronously.

[0131] The counterweight 62 can lower the center of gravity of the fixing portion 5 and increase the center of gravity of the bottom of the container 8 so that it can swing better with the supporting shell 2, which is beneficial for the clamping portion to clamp the container 8.

[0132] The counterweight block 62 is made of material, and a limiter 63 that can generate a circular magnetic field is arranged around the swinging trajectory of the counterweight block 62. The limiter 63 is fixed on the inner wall of the mounting shell 41. The magnetic field generated by the limiter 63 and the counterweight block 62 repel each other. Through the mutual repulsion of the magnetic force, the diameter of the circular trajectory can be prevented from being too large when the bottom of the counterweight block 62 swings, that is, the swing amplitude of the container 8 can be prevented from being too large.

[0133] The limiting member 63 is preferably an electromagnet, which can adjust the size of the magnetic field.

[0134] Example 3

[0135] like Figure 14-21 As shown, it also includes two symmetrically arranged auxiliary fixing units 7, and the two auxiliary fixing units 7 are distributed on both sides of the two synchronization rods 61;

[0136] The auxiliary fixing unit 7 includes a driving member and an auxiliary member for assisting in clamping the container 8. The driving member is arranged on the telescopic area of ​​the vertical part of the synchronization rod 61, and the driving member pushes the auxiliary member to clamp on the surface of the container 8 as the telescopic area of ​​the vertical part of the synchronization rod 61 extends.

[0137] like Figure 18 As shown, the telescopic region of the vertical portion of the synchronization rod 61 is a second telescopic rod 64 arranged vertically, and the second telescopic rod 64 replaces the middle region of the original vertical portion of the synchronization rod 61;

[0138] The driving member is a rotatable transmission roller 77 , which is mounted on the bottom end of the second telescopic rod 64 . The transmission roller 77 that moves downward (outward) is in transmission connection with the auxiliary member.

[0139] The auxiliary member includes a transmission block 71, a transmission inclined surface is provided on the top of the transmission block 71, the transmission inclined surface overlaps the transmission roller 77, and the transmission block 71 is slidable in the horizontal direction;

[0140] An auxiliary clamping plate 76 for clamping the container 8 is fixed on the transmission block 71 , and the auxiliary clamping plate 76 and the transmission inclined surface are located on both sides of the transmission block 71 .

[0141] The transmission block 71 is provided with a connecting portion on both sides, and the connecting portion includes a fixed rod 72 with an "L"-shaped structure. A slider 73 is fixed to the top of the fixed rod 72. The slider 73 is slidably connected to a transverse guide rail 74 arranged along the horizontal direction. The transverse guide rail 74 is arranged parallel to the first telescopic rod 55. The top of the transverse guide rail 74 is connected to the telescopic end of the first telescopic rod 55 through a connecting vertical rod 75, and the connecting vertical rod 75 is located on the inner side of the second telescopic rod 64.

[0142] The second spring is sleeved on the surface of the second telescopic rod 64 , and the length of the second telescopic rod 64 is maintained by the second spring without providing additional potential energy support.

[0143] The slider 73 is connected to one end of the third spring, and the other end of the third spring is fixed on the guide rail. When the third spring is in a normal state, when the clamping arc plate 56 is clamped on the surface of the container 8, the auxiliary clamping plate 76 does not contact the surface of the container 8.

[0144] The top and bottom of the second telescopic rod 64 are connected to the synchronization rod 61 through a connecting rod 65 of a "Z"-shaped structure, thereby increasing the distance between the second telescopic rod 64 and the connecting vertical rod 75 to facilitate the installation of the transmission block 71.

[0145] When the second spring is in a normal state, the third spring does not deform either.

[0146] When the bottom of the container 8 swings in a circular trajectory, the counterweight block 62 also swings accordingly, and the second telescopic rod 64 indirectly connected to the counterweight block 62 is stretched, and the telescopic end of the stretched second telescopic rod 64 moves outward, thereby driving the transmission roller 77 to move synchronously. The moving roller pushes the transmission block 71 toward one side of the container 8 through the transmission inclined surface until the auxiliary clamping plate 76 on the transmission block 71 clamps on the container 8, completing the auxiliary clamping of the container 8.

[0147] The faster the container 8 swings, the greater the clamping force provided by the auxiliary fixing unit 7 , which can further enhance the fixing effect of the container 8 .

[0148] The auxiliary fixing unit 7 utilizes the synchronous swing of the counterweight block 62 when the bottom of the container 8 swings, and automatically drives the auxiliary clamping structure through mechanical linkage. No additional power source is required, and the structure is self-driven.

[0149] The present invention is not limited to the above-described embodiments. Any changes in shape or structure fall within the scope of protection of the present invention. The scope of protection of the present invention is defined by the appended claims. Those skilled in the art may make various changes or modifications to these embodiments without departing from the principles and essence of the present invention. Such changes and modifications shall fall within the scope of protection of the present invention.

Claims

1. A reagent mixing processor for medical immunoassay, comprising a workbench (1), wherein a driving unit is provided inside the workbench (1), wherein the driving unit passes through the top side wall of the workbench (1) shell and is connected to the supporting shell (2) in a biased transmission manner, characterized in that: The driving unit drives the supporting shell (2) to swing in a circular trajectory in the horizontal direction; The bearing shell (2) is located on the top of the workbench (1) and is overlapped with the annular bearing plate (12) on the top of the shell of the workbench (1); A fixing assembly (4) for fixing the reagent container (8), wherein there are a plurality of fixing assemblies (4), and the plurality of fixing assemblies (4) are evenly distributed on the carrying shell (2); The fixing assembly (4) is clamped at the middle or upper middle portion of the container (8), and as the supporting shell (2) swings, the bottom of the container (8) swings in a circle with the clamping point as the center.

2. The medical immunoassay reagent mixing processor according to claim 1, wherein: The driving unit comprises a driving motor (31), the output end of the driving motor (31) is arranged upward, and a driving shaft (32) in a "Z" shape is fixed to the output end of the driving motor (31); The top of the drive shaft (32) passes through the through slot (13) at the top of the workbench (1) shell and the inner ring of the bearing ring in sequence, and is fixedly connected to the circular connecting block (33) at the bottom of the bearing shell (2). The connecting block (33) is located in the inner ring cavity of the bearing ring.

3. The reagent mixing processor for medical immunoassay according to claim 2, characterized in that: The connecting block (33) is fixed at a deflected position on the bottom of the carrying shell (2), and the driving motor (31) is fixed to the side wall of the bottom of the inner cavity of the workbench (1) via an "L"-shaped connecting piece.

4. The medical immunoassay reagent mixing processor according to claim 1, wherein: The fixing assembly (4) comprises a mounting shell (41), and a clamping portion for clamping and fixing the container (8) is provided above the inner cavity of the mounting shell; The clamping portion comprises an outer supporting unit and an inner clamping unit, and the inner clamping unit clamps and fixes the container (8); The inner clamping unit is sleeved inside the outer supporting unit, and the inner clamping unit is sleeved inside the outer supporting unit and rotates, and the outer supporting unit is fixed on the mounting shell (41).

5. The medical immunoassay reagent mixing processor according to claim 4, characterized in that: The outer surface of the inner clamping unit and the outward extension surface of the outer surface form a complete spherical structure, and the inner cavity surface of the outer supporting unit and the outward extension surface of the inner cavity surface form a complete spherical structure.

6. The reagent mixing processor for medical immunoassay according to claim 5, characterized in that: The outer supporting unit comprises a plurality of position-limiting outer covers (51) distributed in a circular array, wherein two adjacent position-limiting outer covers (51) are connected to each other via connecting arc rods (52), wherein support rods (53) are fixed on the outer walls of at least two position-limiting outer covers (51), and the support rods (53) are fixed on the inner wall of the mounting shell (41); The inner walls of all the limiting outer covers (51) together form a spherical structure, and the limiting outer covers (51) are fitted on the outer wall of the inner clamping unit.

7. The reagent mixing processor for medical immunoassay according to claim 6, characterized in that: The inner clamping unit comprises a self-rotating shell (54) having an overall annular structure and an outer wall having a spherical structure, wherein the outer wall of the self-rotating shell (54) is in contact with the inner wall of the limiting outer cover (51); A clamping member is arranged in the inner cavity of the self-rotating shell (54), the clamping member is clamped on the surface of the container (8), and the container (8) passes through the self-rotating shell (54).

8. The reagent mixing processor for medical immunoassay according to claim 7, characterized in that: The clamping member comprises two symmetrically arranged clamping arc plates (56), and the clamping arc plates (56) are connected to the inner wall of the rotation shell (54) via a first telescopic rod (55) arranged in the horizontal direction; A first spring is sleeved on the surface of the first telescopic rod (55), and the container (8) is clamped by the elastic force provided by the first spring.

9. The reagent mixing processor for medical immunoassay according to claim 8, characterized in that: The container (8) further comprises a counterweight portion (6) that facilitates the follow-up movement of the clamping portion. The counterweight portion (6) comprises two symmetrically arranged "L"-shaped synchronization rods (61). The vertical portions of the two synchronization rods (61) are distributed along both sides of the clamped container (8), and the vertical portions extend to the bottom of the container (8). The horizontal portions of the two synchronization rods (61) are located at the bottom of the container (8) and are both connected to the top of a counterweight block (62). The counterweight block (62) is located directly below between the two clamping arc plates (56). The top of the synchronization rod (61) is fixed to the telescopic end of the first telescopic rod (55); Furthermore, the horizontal portion of the synchronization rod (61) is retractable.

10. The reagent mixing processor for medical immunoassay according to claim 9, characterized in that: It also includes two symmetrically arranged auxiliary fixing units (7), the two auxiliary fixing units (7) being distributed on both sides of the two synchronization rods (61); The auxiliary fixing unit (7) includes a driving member and an auxiliary member for assisting in clamping the container (8), wherein the driving member is arranged on the telescopic region of the vertical portion of the synchronization rod (61), and the driving member pushes the auxiliary member to clamp on the surface of the container (8) as the telescopic region of the vertical portion of the synchronization rod (61) extends.

Images