High yield vectors

By designing sample spots adapted to single biomolecules on the carrier surface and incubating them under saturating conditions, the problem of low single-molecule immobilization efficiency is solved, and high-yield single-molecule event analysis, especially sequence analysis of single nucleic acid molecules, is achieved.

CN120813701APending Publication Date: 2025-10-17GNOTHIS HLDG
View PDF 9 Cites 0 Cited by

Patent Information

Application Number
CN202380084144.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Priority Date
2022-12-06
Filing Date
2023-11-30
Publication Date
2025-10-17

Smart Images

  • Figure HDA0005437170910000011
    Figure HDA0005437170910000011
  • Figure HDA0005437170910000021
    Figure HDA0005437170910000021
  • Figure HDA0005437170910000031
    Figure HDA0005437170910000031
Patent Text Reader

Abstract

The present disclosure relates to carriers and methods of making such carriers comprising a substrate and a plurality of sample sites on a surface of the carrier, where the sample sites are spatially separated from one another, and where a single biomolecule is immobilized on a single sample site.
Need to check novelty before this filing date? Find Prior Art

Citation Information

Patent Citations

  • Method and device for assessing the suitability of biopolymers

    EP0679251A1

  • Composition and method for nucleic acid sequencing

    US7745116B2

  • Use of optical diffraction elements in detection methods

    WO2002097406A1

  • Evanescence-based multiplex sequencing method

    WO2003052137A2

  • Parallel high throughput single molecule sequencing process

    WO2006013110A1