Edible combined preparation for regulating spleen and stomach

Abstract

The invention relates to an edible combined preparation for regulating spleen and stomach and clearing damp, and belongs to the field of homology of medicine and food. The combined preparation comprises medicinal and edible plant components such as Chinese yam, bighead atractylodes rhizome, poria cocos, coix seeds, hyacinth beans, dried tangerine or orange peel, lotus seeds, Chinese dates, fresh ginger and liquorice, and the medicinal and edible plant components are compatible according to a specific proportion to construct a synergistic effect mechanism of tonifying spleen and qi and eliminating dampness and turbidity. The preparation is prepared through the steps of functional group extraction, vacuum concentration, spray drying, wet granulation and the like, and granules, powder or electuary products are obtained and have the advantages of being stable in component, good in instant solubility and high in palatability.

Description

Technical Field

[0001] The present invention relates to the technical field of medicine and food homology, and in particular to an edible combination preparation for regulating the spleen and stomach. Background Art

[0002] In traditional Chinese medicine, the spleen and stomach are considered the "foundation of acquired constitution and the source of Qi and blood." They are responsible for transporting and transforming nutrients, promoting the flow of clear fluids, and providing nutritional support for maintaining normal physiological activities. Due to factors such as unhealthy diets, work pressure, and irregular work and rest schedules, the incidence of spleen and stomach dysfunction in the modern population is increasing year by year. These symptoms include loss of appetite, abdominal distension, loose stools, limb fatigue, and a sallow complexion. In severe cases, these conditions can even develop into chronic digestive diseases. Therefore, daily conditioning the spleen and stomach to enhance their transport and transformation capabilities has become an important approach to preventing disease and maintaining health.

[0003] Currently, there are several edible combination products on the market that aim to regulate the spleen and stomach. These often use ingredients like Chinese yam, Atractylodes macrocephala, and Poria cocos as their primary ingredients, aiming to improve digestion and absorption by tonifying the spleen. Other products focus on dispelling dampness and promoting diuresis, such as by incorporating coix seed, lentils, and dried tangerine peel, to alleviate indigestion symptoms caused by dampness trapped in the middle burner. However, these products often focus on a single approach—either tonifying the spleen and nourishing the stomach or dispelling dampness and stagnating stagnation. These products often fail to address the dual goals of "tonifying while dispelling, dispelling while tonifying," limiting their intended users and resulting in limited effectiveness.

[0004] Traditional formulas or modern preparations often fail to take into account the balanced relationship between strengthening the spleen and replenishing Qi and removing dampness and turbidity, resulting in the phenomenon of "tonifying but stagnating the middle" or "removing but damaging the body". In addition, there is a lack of systematic integration in the combination of ingredients, and the synergistic effect between multiple medicinal and edible ingredients cannot be achieved, affecting the actual conditioning effect. At the same time, the dosage forms are mostly coarse particles or pieces of medicine, which have poor taste and solubility, and are difficult to meet the needs of modern consumer groups for ready-to-drink, portable, and gentle conditioning. Therefore, an edible combination preparation is proposed that can achieve the dual functions of strengthening the spleen and replenishing Qi and removing dampness and transporting turbidity at the dietary level, and is suitable for modern sub-healthy people. Summary of the Invention

[0005] In view of the deficiencies in the prior art, the present invention provides an edible combination preparation for regulating the spleen and stomach, which solves the problems raised in the background art.

[0006] The above technical objectives of the present invention are achieved through the following technical solutions:

[0007] An edible combination preparation for regulating the spleen and stomach, comprising the following medicinal and edible plant raw materials in a combination proportion by weight:

[0008] 18-25 servings of Chinese yam;

[0009] 12-18 parts of Poria cocos;

[0010] 8-12 parts of Atractylodes macrocephala;

[0011] 18-25 parts coix seed;

[0012] 8-12 servings of lentils;

[0013] 4-6 parts dried tangerine peel;

[0014] 4-6 lotus seeds;

[0015] 6-10 servings of jujube;

[0016] 1-3 portions of ginger;

[0017] 3-6 parts of licorice;

[0018] Among them, the total weight of yam, white atractylodes and poria accounts for 40-50% of the total preparation, and the total weight of coix seed and lentil is not less than 30%. The combined preparation is any one of granules, instant preparations, powders or substitute tea.

[0019] Preferably, the Chinese yam, Poria cocos, Atractylodes macrocephala, lotus seeds, jujubes and liquorice constitute the first functional component, which is responsible for strengthening the spleen and replenishing the middle; coix seed, lentil, tangerine peel and ginger constitute the second functional component, which is responsible for removing dampness and regulating qi.

[0020] Preferably, each raw material is decocted and extracted according to functional groups, concentrated separately and then combined and spray-dried;

[0021] The spray drying adopts an air inlet temperature of 150-165° C. and an air outlet temperature of 85-95° C., and the effective component retention rate in the obtained dry powder is not less than 90%.

[0022] Preferably, the jujubes are pitted before use, and the ginger is dried ginger slices obtained by low-temperature drying fresh ginger.

[0023] Preferably, the particle size of the granules is controlled between 30 and 60 meshes, and the brewing time does not exceed 30 seconds to form a uniform solution;

[0024] It is suitable for daily consumption and conditioning for people in sub-healthy conditions such as weak spleen and stomach, dampness in the middle, loss of appetite, abdominal distension and loose stools, and sleepy limbs.

[0025] A method for preparing an edible combination preparation for regulating the spleen and stomach comprises the following steps:

[0026] (1) Weigh 18-25 parts of Chinese yam, 12-18 parts of Poria cocos, 8-12 parts of Atractylodes macrocephala, 18-25 parts of Coix seeds, 8-12 parts of Lentils, 4-6 parts of Tangerine peel, 4-6 parts of Lotus seeds, 6-10 parts of Jujube, 1-3 parts of Ginger, and 3-6 parts of Licorice according to the following weight ratio; wash the raw materials, dry them at a low temperature below 45°C, and grind them;

[0027] (2) Dioscorea opposita, Poria cocos, Atractylodes macrocephala, lotus seeds, jujube, and licorice constitute the first extraction group, and coix seed, lentil, dried tangerine peel, and ginger constitute the second extraction group. Each group is decocted twice with water (8 times the amount of water each time, 40 minutes), the residue is filtered to obtain the liquid, and the decoction is combined for later use;

[0028] (3) The filtrates were combined and concentrated under reduced pressure to 1 / 3 of their original volume;

[0029] (4) combining the concentrated solutions and spray drying them;

[0030] (5) The spray-dried material is mixed with the excipients and then wet granulated. After drying and screening, it is packaged into granules.

[0031] Preferably, 5% to 10% of dextrin or starch is added as a binder during the granulation process, and after granulation, hot air drying is adopted at a temperature below 60° C. for a drying time of not less than 4 hours.

[0032] Preferably, the particle size of the powder after spray drying is controlled below 80 mesh, and the moisture content of the dried product is controlled at 5% to 8% to ensure the solubility and storage stability of the product.

[0033] In summary, the present invention mainly has the following beneficial effects:

[0034] Compared with the prior art, the present invention has the following beneficial effects:

[0035] The present invention realizes the synergy of multiple effects such as strengthening the spleen, removing dampness, regulating qi, and nourishing the heart through the design of compound structure. It not only improves the symptoms of spleen and stomach weakness, but also can effectively deal with the manifestations such as abdominal distension, loose stools, and fatigue caused by dampness in the middle burner, and meets the multi-dimensional conditioning needs of sub-healthy people.

[0036] There is a clear functional division and proportional coordination relationship between each component. By using yam + Atractylodes macrocephala to nourish the spleen, coix seed + lentil to remove dampness, and tangerine peel + ginger to regulate qi and invigorate the spleen, a conditioning structure with layered functions is constructed, which is different from the traditional "homogeneous mixing" concept of compound prescriptions and strengthens the systematic nature of the prescription.

[0037] The process adopts a combination of group decoction, independent concentration, spray drying and wet granulation to ensure the retention of heat-sensitive components and the stability of effective ingredients. The product has a soft taste, good instant solubility, and good industrial conversion capabilities. DETAILED DESCRIPTION

[0038] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below in combination with the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all the embodiments. Based on the described embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0039] The following examples are intended to illustrate the present invention but are not intended to limit the scope of protection of the present invention. The conditions in the examples may be further adjusted according to specific conditions. Simple improvements to the method of the present invention within the scope of the present invention are also within the scope of protection claimed in the present invention.

[0040] The technical solution of this patent is further described in detail below in conjunction with specific implementation methods.

[0041] Example 1

[0042] An edible combination preparation for regulating the spleen and stomach, comprising the following raw materials:

[0043] Raw material preparation

[0044] Weigh the raw materials according to the following weight ratio: 18-25 parts of Chinese yam;

[0045] 12-18 parts of Poria cocos;

[0046] 8-12 parts of Atractylodes macrocephala;

[0047] 18-25 parts coix seed;

[0048] 8-12 servings of lentils;

[0049] 4-6 parts dried tangerine peel;

[0050] 4-6 lotus seeds;

[0051] 6-10 servings of jujube;

[0052] 1-3 portions of ginger;

[0053] 3-6 parts of licorice;

[0054] The jujubes used are seedless red dates, which need to be pitted in advance; the ginger used is fresh ginger, which is air-dried at a temperature below 45°C to a moisture content of <10%, and then sliced ​​for later use;

[0055] All raw materials were washed with running water to remove sand and impurities, drained, and dried in a hot air drying oven at 45°C for 6 hours until the surface was dry and no obvious moisture remained;

[0056] After drying, all raw materials were crushed into coarse powder (passed through a 20-mesh sieve) for subsequent decoction and extraction.

[0057] Feature grouping and extraction

[0058] According to the raw material efficacy and extraction requirements, the extraction is divided into two groups:

[0059] (1) The first functional group (spleen-strengthening and qi-invigorating group):

[0060] Including Chinese yam, Poria cocos, Atractylodes macrocephala, lotus seeds, jujube, and licorice;

[0061] Add 8 times the volume of purified water to the total raw materials of this group, decoct twice, 40 minutes each time, maintain a slight boiling state at 90-95℃, and stir evenly;

[0062] The two decoctions were combined and filtered to obtain the first extract.

[0063] (2) The second functional group (dampness-removing and qi-regulating group):

[0064] Includes coix seed, lentil, tangerine peel, and ginger;

[0065] Add 8 times the volume of purified water and decoct twice, each time for 40 minutes;

[0066] After combining the filtrates, a second extract was obtained.

[0067] Reduced pressure concentration

[0068] The first extract and the second extract are placed in concentration tanks respectively, and each extract is concentrated to 1 / 3 of the original volume by using a reduced pressure concentration process below 70°C;

[0069] The concentrate is semi-fluid with moderate viscosity and specific gravity controlled between 1.25 and 1.30;

[0070] The two concentrates were mixed evenly in a volume ratio of 1:1 to obtain a unified concentrate for spray drying.

[0071] spray drying

[0072] Place the mixed concentrate into the spray dryer storage tank and set the nozzle atomization pressure to 0.6 MPa;

[0073] The drying parameters were set to an inlet air temperature of 155°C and an outlet air temperature of 90°C;

[0074] After continuous spray drying, the dry powder is collected. The particles are light yellow to light brown, loose, and have no burnt smell.

[0075] The obtained dry powder was passed through an 80-mesh sieve to remove lumps and impurities.

[0076] Excipient mixing and wet granulation

[0077] Mix the dry powder with maltodextrin at a ratio of main drug powder to auxiliary material of 1:0.2;

[0078] Add 5% starch paste as a binder and use a high-speed stirring granulator for wet granulation to form wet granules;

[0079] Spread the wet granules on a baking tray and place them in a hot air circulation oven at 60°C to dry for 4 hours until the moisture content of the granules drops to ≤8%;

[0080] The dried particles are sieved to 30-60 mesh, and particles with complete shape and uniform size are retained as the finished product.

[0081] Packaging and storage

[0082] The dried qualified granules were divided into 3g per bag, placed in composite aluminum foil bags, and sealed;

[0083] After packaging, store in a cool, dry place, away from direct sunlight and high humidity;

[0084] The finished product is light yellow to yellowish brown granules with a light aroma and slightly sweet taste. It is suitable for brewing with boiling water and has good solubility.

[0085] Although the embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that, unless otherwise defined, the technical or scientific terms used in the present invention shall have the ordinary meanings understood by persons having ordinary skills in the field to which the present invention belongs. The words "include" or "comprise" and the like used in the present invention mean that the elements or objects preceding the word include the elements or objects listed after the word and their equivalents, without excluding other elements or objects. The words "connect" or "connected" and the like are not limited to physical or mechanical connections, but may also include electrical connections, whether direct or indirect. The words "upper", "lower", "left", "right", etc. are only used to indicate relative position relationships. When the absolute position of the described object changes, the relative position relationship may also change accordingly.

[0086] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. An edible combination preparation for regulating the spleen and stomach, characterized in that: The composition includes the following medicinal and edible plant raw materials in proportions by weight: 18-25 servings of Chinese yam; 12-18 parts of Poria cocos; 8-12 parts of Atractylodes macrocephala; 18-25 parts coix seed; 8-12 servings of lentils; 4-6 parts dried tangerine peel; 4-6 lotus seeds; 6-10 servings of jujube; 1-3 portions of ginger; 3-6 parts of licorice; Among them, the total weight of yam, white atractylodes and poria accounts for 40-50% of the total preparation, and the total weight of coix seed and lentil is not less than 30%. The combined preparation is any one of granules, instant preparations, powders or substitute tea.

2. An edible combination preparation for regulating the spleen and stomach according to claim 1, characterized in that: The Chinese yam, Poria cocos, Atractylodes macrocephala, lotus seeds, jujubes and liquorice constitute the first functional component, which is responsible for strengthening the spleen and replenishing the middle; the coix seed, lentil, tangerine peel and ginger constitute the second functional component, which is responsible for removing dampness and regulating qi.

3. The edible combination preparation for regulating the spleen and stomach according to claim 1, characterized in that: Each raw material was decocted and extracted according to its functional group, concentrated separately and then combined and spray-dried; The spray drying adopts an air inlet temperature of 150-165° C. and an air outlet temperature of 85-95° C., and the effective component retention rate in the obtained dry powder is not less than 90%.

4. The edible combination preparation for regulating the spleen and stomach according to claim 1, characterized in that: The jujubes are pitted before use, and the ginger is dried ginger slices obtained by low-temperature drying of fresh ginger.

5. The edible combination preparation for regulating the spleen and stomach according to claim 1, characterized in that: The particle size of the granules should be controlled between 30 and 60 meshes, and the brewing time should not exceed 30 seconds to form a uniform solution; It is suitable for daily consumption and conditioning for people in sub-healthy conditions such as weak spleen and stomach, dampness in the middle, loss of appetite, abdominal distension and loose stools, and sleepy limbs.

6. The method for preparing the edible combined preparation for regulating the spleen and stomach according to claim 1, comprising the following steps: (1) Weigh 18-25 parts of Chinese yam, 12-18 parts of Poria cocos, 8-12 parts of Atractylodes macrocephala, 18-25 parts of Coix seeds, 8-12 parts of Lentils, 4-6 parts of Tangerine peel, 4-6 parts of Lotus seeds, 6-10 parts of Jujube, 1-3 parts of Ginger, and 3-6 parts of Licorice according to the following weight ratio; wash the raw materials, dry them at a low temperature below 45°C, and grind them; (2) Dioscorea opposita, Poria cocos, Atractylodes macrocephala, lotus seeds, jujube, and licorice constitute the first extraction group, and coix seed, lentil, dried tangerine peel, and ginger constitute the second extraction group. Each group is decocted twice with water (8 times the amount of water each time, 40 minutes), the residue is filtered to obtain the liquid, and the decoction is combined for later use; (3) The filtrates were combined and concentrated under reduced pressure to 1 / 3 of their original volume; (4) combining the concentrated solutions and spray drying them; (5) The spray-dried material is mixed with the excipients and then wet granulated. After drying and screening, it is packaged into granules.

7. The method for preparing the edible combined preparation for regulating the spleen and stomach according to claim 6, characterized in that: During the granulation process, 5% to 10% of dextrin or starch is added as a binder. After granulation, hot air drying below 60° C. is adopted for drying for not less than 4 hours.

8. The method for preparing the edible combined preparation for regulating the spleen and stomach according to claim 6, characterized in that: The particle size of the powder after spray drying is controlled below 80 mesh, and the moisture content in the dried product is controlled at 5% to 8% to ensure the solubility and storage stability of the product.