Flomoxef acid medical intermediate drying and storing equipment

Abstract

The invention relates to the technical field of medical intermediate storage, in particular to flomoxef acid medical intermediate drying and storing equipment which comprises a rack and a storage tank fixedly connected to the top of the rack in a penetrating mode, a suction pump is installed on the top of the rack, a barrel is vertically and fixedly connected to the rack in a penetrating mode, and a weighing disc is arranged on the inner side of the barrel. And an electric opening and closing plate is mounted on the weighing disc. The driving motor is started to enable the rotary porous disc to be communicated with the fixed porous disc, intermediates in the storage tank are discharged into the weighing disc through the rotary porous disc and the fixed porous disc to be weighed, and when the discharged intermediates reach the required weight, the rotary porous disc is rotated, reset and closed; and then the electric opening and closing plate and the electric control valve are started to discharge the intermediate on the weighing disc, due to the action of the fixed porous disc and the rotary porous disc, the discharged intermediate is separated from the remaining intermediate, moisture of the remaining intermediate due to the fact that water vapor enters the storage tank can be prevented, and therefore the intermediate storage effect is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of pharmaceutical intermediate storage, in particular to a drying and storage device for a fluoxetine pharmaceutical intermediate. Background Art

[0002] As an important pharmaceutical intermediate, fluoxetine has extensive applications in the pharmaceutical industry. During its production, drying and storage are crucial steps, directly impacting product quality and stability.

[0003] The Chinese patent with announcement number CN220097244U discloses an intermediate drying and storage device, including a storage tank and a discharge pipe, the discharge pipe is arranged at the bottom of the storage tank, and also includes a mounting frame, the mounting frame is installed on the storage tank, a feeding assembly, the feeding assembly is installed on the mounting frame, the feeding assembly is connected to the inlet of the storage tank, and a curved partition, the curved partition is arranged in the storage tank, the front and rear ends of the curved partition are connected to the inner wall of the storage tank, the upper surface of the storage tank and the upper side of the inner wall of the storage tank form a curved feeding channel. Although the above patent can dry and store the intermediates, when the discharge pipe is opened to discharge the intermediates, although the remaining intermediates can block the discharge port of the storage tank to prevent external air from entering, since the intermediates are in powder form, there are still gaps between the intermediates. Some water vapor in the air will still enter the storage tank, causing some intermediates to become moist, affecting the storage effect of the intermediates.

[0004] The present invention aims to solve the problems existing in the above-mentioned patents. To this end, a drying and storage device for fluoxetine pharmaceutical intermediates is proposed, which can separate the discharged intermediates from the remaining intermediates, prevent water vapor from entering the storage tank and causing the remaining intermediates to become wet, and improve the storage effect of the intermediates. Summary of the Invention

[0005] In order to overcome the disadvantage that since the intermediates are in powder form and there are gaps between the intermediates, some water vapor in the air will still enter and cause some intermediates to become moist, thereby affecting the storage effect of the intermediates, the present invention provides a drying and storage device for fluoxetine pharmaceutical intermediates, which can separate the discharged intermediates from the remaining intermediates, prevent water vapor from entering the storage tank and causing the remaining intermediates to become moist, and improve the storage effect of the intermediates.

[0006] The present invention is achieved through the following technical solutions:

[0007] A drying and storage device for fluoxetine pharmaceutical intermediates, comprising a frame and a storage tank fixedly connected to the top of the frame, a suction pump installed on the top of the frame, a cylinder fixedly connected to the frame vertically, a weighing plate installed inside the cylinder, an electric opening and closing plate installed on the weighing plate, and a drying component installed on the storage tank, the drying component is connected to the discharge end of the suction pump, and is used to transport and dry the intermediates, a discharge pipe is connected to the bottom of the cylinder, an electric control valve is installed on the discharge pipe, a collecting hopper is fixedly connected to the inside of the cylinder along the circumference, a fixed porous plate is fixedly connected to the inside of the collecting hopper along the circumference, and the top of the fixed porous plate is fixedly connected to the top of the fixed porous plate. The cylinder is rotatably connected to a rotating porous disk, and a driving motor is installed on the cylinder. The output shaft of the driving motor is connected to the circumference of the rotating porous disk through a synchronous belt assembly. The driving motor is used to drive the rotating porous disk to rotate, and the rotating porous disk rotates to open and close the fixed porous disk. When opened, the intermediate falls downward into the weighing disk. When closed, the intermediate stops falling downward, so that the discharged intermediate is separated from the remaining intermediate, and then the intermediate on the weighing disk is completely discharged. A conveying assembly is provided between the cylinder and the collecting hopper, which is used to drive the intermediate to be conveyed downward evenly.

[0008] Further explanation, the conveying assembly includes a fixed plate fixed to the inner side of the collecting hopper, and a spiral conveying plate that is rotatably connected to the fixed plate and contacts the inner side of the collecting hopper, which is used to drive the intermediate to move downward for conveying. A stepper motor is installed on the cylinder, and the output shaft of the stepper motor and the spiral conveying plate are connected through a synchronous belt assembly.

[0009] Further explanation, the drying component includes a fixed pipe fixedly connected to the storage tank, the end of the fixed pipe is connected to the discharge end of the suction pump, an opening is opened on the right side of the bottom of the fixed pipe, which is used to discharge the dried intermediate, an exhaust pipe is fixedly connected to the storage tank, the end of the exhaust pipe is fixedly connected to the fixed pipe, an air intake pipe is fixedly connected to the storage tank, the end of the air intake pipe is fixedly connected to the fixed pipe, a spiral shaft is rotatably connected between the fixed pipe and the storage tank, which is used to drive the intermediate to move to the right for uniform drying, a servo motor is installed on the storage tank, the output shaft end of the servo motor is fixedly connected to the end of the spiral shaft, and a blocking component is provided on the fixed pipe to block the intermediate.

[0010] To further illustrate, the blocking assembly includes a frame symmetrically fixed to the inner side of the fixed pipe, a microporous filter membrane is fixed to the inner side of the frame, and the microporous filter membrane corresponds to the exhaust pipe and the intake pipe and is used to block the intermediate body.

[0011] Further explanation: the drying and storage equipment for fluoxetine pharmaceutical intermediates also includes a stirring assembly, which includes a rotating frame that is rotatably connected to the storage tank, and a heating rod is symmetrically fixed on the rotating frame for further drying the intermediate. A driving assembly is provided between the rotating frame and the storage tank for driving the rotating frame to rotate.

[0012] To further illustrate, the driving assembly includes a worm gear fixedly mounted on the rotating frame, a dual-axis motor is mounted on the storage tank, and a worm engaged with the worm gear is fixedly connected to the end of the output shaft of the dual-axis motor.

[0013] Further explanation, the drying and storage equipment for fluoxetine pharmaceutical intermediates also includes a sealing assembly, which includes evenly spaced embedded air bags fixed to the top circumference of the fixed porous disk, for sealing the holes of the rotating porous disk, an air duct is connected between the air bags, the air duct is fixed through the fixed porous disk, a fixed frame is fixed to the inside of the cylinder, a cylinder body is fixed to the inside of the fixed frame, a piston rod is slidably connected to the inside of the cylinder body, a connecting pipe fixedly connected to the air duct is connected to the cylinder body, a cylinder is fixed to the inside of the fixed frame, and the end of the telescopic rod of the cylinder is fixedly connected to the end of the piston rod.

[0014] Further explanation: the dry storage equipment for fluoxymethane pharmaceutical intermediates also includes a corrugated cover connected between the discharge end of the collecting hopper and the feed end of the discharge pipe to block the flying intermediates.

[0015] The beneficial effects of the present invention are:

[0016] 1. The intermediate is dried by hot air and then discharged into the storage tank for storage. The rotating porous disk and the fixed porous disk block the intermediate. When the intermediate is needed, the drive motor is started to connect the rotating porous disk and the fixed porous disk. The intermediate in the storage tank is discharged into the weighing disk through the rotating porous disk and the fixed porous disk for weighing. When the discharged intermediate reaches the required weight, the rotating porous disk rotates and resets to close. Then the electric opening and closing plate and the electric control valve are started to discharge the intermediate on the weighing disk. Due to the action of the fixed porous disk and the rotating porous disk, the discharged intermediate is separated from the remaining intermediate, which can prevent water vapor from entering the storage tank and causing the remaining intermediate to become wet, thereby improving the storage effect of the intermediate.

[0017] 2. Under the action of the heating rod, whenever the intermediate is stored for a long time, the heating rod is started to heat, and at the same time, the heating rod is rotated to stir and dry the intermediate, which can prevent the intermediate from being wet due to water droplets in the storage tank in the environment of south wind, thereby ensuring the dryness of the intermediate.

[0018] 3. Under the action of the airbag, whenever the rotating porous disk is not connected with the fixed porous disk, the airbag expands to seal the holes of the rotating porous disk, preventing the intermediate from entering the gap between the rotating porous disk and the fixed porous disk and affecting the rotation of the rotating porous disk, thereby ensuring the smooth rotation of the rotating porous disk. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention.

[0020] Figure 2 It is a schematic diagram of the three-dimensional structure of the weighing plate and the electric opening and closing plate of the present invention.

[0021] Figure 3 It is a schematic diagram of the three-dimensional structure of the air supply pump, three-way pipe and collecting hopper of the present invention.

[0022] Figure 4 This is a schematic diagram of the three-dimensional structure of the fixed porous disk, the rotating porous disk and the driving motor of the present invention.

[0023] Figure 5 This is a structural separation diagram of the fixed porous disk and the rotating porous disk of the present invention.

[0024] Figure 6 It is a schematic diagram of the three-dimensional structure of the drying component of the present invention.

[0025] Figure 7 It is a schematic cross-sectional structural diagram of the fixed tube of the present invention.

[0026] Figure 8 It is a schematic diagram of the three-dimensional structure of the stirring assembly of the present invention.

[0027] Figure 9 It is a schematic diagram of the three-dimensional structure of the sealing component of the present invention.

[0028] Figure 10 It is a schematic diagram of the three-dimensional structure of the air guide pipe and the connecting pipe of the present invention.

[0029] Figure 11 It is a schematic diagram of the three-dimensional structure of the bellows of the present invention.

[0030] Names of the labels in the figure: 1. Frame, 2. Storage tank, 3. Suction pump, 4. Cylinder, 5. Weighing plate, 6. Electric opening and closing plate, 7. Discharge pipe, 8. Electric control valve, 9. Air supply pump, 10. Three-way pipe, 11. Collecting hopper, 12. Stepper motor, 121. Fixed plate, 122. Screw conveyor plate, 13. Fixed porous plate, 14. Rotating porous plate, 15. Drive motor, 16. Fixed pipe, 161. Inlet pipe, 1 62. Exhaust pipe, 163. Servo motor, 164. Screw shaft, 165. Opening, 166. Frame, 167. Microporous filter membrane, 17. Rotating frame, 171. Heating rod, 172. Worm gear, 173. Dual-axis motor, 174. Worm, 18. Airbag, 181. Fixed frame, 182. Cylinder, 183. Cylinder body, 184. Piston rod, 185. Air guide tube, 186. Connecting pipe, 19. Bellows. DETAILED DESCRIPTION

[0031] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0032] Example: A drying and storage device for fluoxetine pharmaceutical intermediates, see Figure 1-Figure 7 As shown, it includes a frame 1 and a storage tank 2 vertically fixed and connected to the middle of the top of the frame 1. A suction pump 3 is installed on the left side of the top of the frame 1. The suction pump 3 can pump the intermediate. A cylinder 4 is vertically fixed and connected to the middle of the lower part of the frame 1. A weighing plate 5 is provided on the lower inner side of the cylinder 4. An electric opening and closing plate 6 is installed under the weighing plate 5. The electric opening and closing plate 6 can control the discharge of the intermediate on the weighing plate 5. The electric opening and closing plate 6 is composed of a circular plate and a micro motor, wherein the circular plate is rotatably connected to the weighing plate 5. At the lower left side of the weighing plate 5, the circular plate contacts the inner side of the weighing plate 5, the micro motor is installed on the outer left side of the weighing plate 5, and the output shaft end of the micro motor is fixedly connected to the shaft of the circular plate. It also includes a discharge pipe 7, an electric control valve 8, an air supply pump 9, a three-way pipe 10, a collecting hopper 11, a conveying component, a fixed porous plate 13, a rotating porous plate 14, a drive motor 15 and a drying component. A drying component is provided on the upper part of the storage tank 2, and the drying component is connected to the discharge end of the suction pump 3. When the drying component is in operation, the drying component is dried. The dry component can realize the conveying and drying of the intermediate. The middle of the bottom of the cylinder 4 is connected to a discharge pipe 7, and an electric control valve 8 is installed at the lower part of the discharge pipe 7. The upper part of the inner side of the cylinder 4 is fixedly connected with a collecting hopper 11 along the circumference. The middle part of the inner side of the collecting hopper 11 is fixedly connected with a fixed porous disk 13 along the circumference. The top of the fixed porous disk 13 is rotatably connected with a rotating porous disk 14. A driving motor 15 is installed on the upper right side of the cylinder 4. The output shaft of the driving motor 15 is connected to the circumference of the outer side of the rotating porous disk 14 through a synchronous belt assembly. Next, the driving motor 15 is used to drive the rotating porous disk 14 to rotate, and the rotating porous disk 14 rotates to open and close the fixed porous disk 13. When opened, the intermediate falls downward into the weighing disk 5. When closed, the intermediate stops falling downward, so that the discharged intermediate is separated from the remaining intermediate, and then the intermediate on the weighing disk 5 is completely discharged. A conveying component is provided between the cylinder 4 and the collecting hopper 11. When the conveying component is in operation, the conveying component can drive the intermediate to be evenly conveyed downward.

[0033] See also Figure 3 and Figure 4As shown, the conveying assembly includes a stepper motor 12, a fixed plate 121 and a spiral conveying plate 122. The fixed plate 121 is fixedly connected to the lower left part of the collecting hopper 11, and the spiral conveying plate 122 is rotatably connected to the right side of the fixed plate 121. The spiral conveying plate 122 is in contact with the lower inner part of the collecting hopper 11. When the spiral conveying plate 122 rotates, the spiral conveying plate 122 can drive the intermediate to move downward for conveying. The stepper motor 12 is installed on the upper left part of the cylinder 4, and the output shaft of the stepper motor 12 is connected to the lower part of the spiral conveying plate 122 through a synchronous belt assembly.

[0034] See also Figure 6 and Figure 7 As shown, the drying assembly includes a fixed pipe 16, an air inlet pipe 161, an exhaust pipe 162, a servo motor 163, a spiral shaft 164 and a blocking assembly. The upper part of the storage tank 2 is fixedly connected with the fixed pipe 16, the left end of the fixed pipe 16 is connected to the discharge end of the suction pump 3, and an opening 165 is opened on the right side of the bottom of the fixed pipe 16. The opening 165 is used to discharge the dried intermediate. The upper front part of the storage tank 2 is fixedly connected with the exhaust pipe 162, the rear end of the exhaust pipe 162 is fixedly connected to the front side of the fixed pipe 16, the upper rear part of the storage tank 2 is fixedly connected with the air inlet pipe 161, the front end of the air inlet pipe 161 is fixedly connected to the rear end of the fixed pipe 16, and the right side of the fixed pipe 16 is rotatably connected with the spiral shaft 16 4. When the screw shaft 164 rotates, the screw shaft 164 can drive the intermediate to move to the right for uniform drying. A servo motor 163 is installed on the upper right side of the storage tank 2. The output shaft end of the servo motor 163 is fixedly connected to the right end of the screw shaft 164. A blocking component is provided on the fixed tube 16. When the blocking component is in operation, the blocking component can block the intermediate; the blocking component includes a frame 166 and a microporous filter membrane 167. The frame 166 is fixedly connected to the inner side of the fixed tube 16 symmetrically front and back. The microporous filter membranes 167 are fixedly connected to the inner sides of the front and rear frames 166. The front microporous filter membrane 167 corresponds to the exhaust pipe 162, and the rear microporous filter membrane 167 corresponds to the intake pipe 161. The microporous filter membrane 167 can block the intermediate.

[0035] Initially, the air inlet pipe 161 is externally connected to a hot air pump, the exhaust pipe 162 is externally connected to a discharge pipe, and the air supply pump 9 is externally connected to nitrogen. First, the suction end of the suction pump 3 is placed in the fluoxetine pharmaceutical intermediate, and then the servo motor 163 is started to drive the screw shaft 164 to reverse, and the external hot air pump is started at the same time. The hot air pump discharges the hot air into the air inlet pipe 161, and the hot air in the air inlet pipe 161 passes through the rear microporous filter membrane 167 and is discharged into the fixed pipe 16. As the hot air continues to flow, the hot air flows forward through the front microporous filter membrane 167 and is discharged into the exhaust pipe 162. The suction pump 3 is started, and the suction pump 3 draws the intermediate into the fixed pipe 16 and contacts the screw shaft 164. The screw shaft 164 reverses and drives the intermediate to move to the right for transportation. The intermediate moving to the right contacts the hot air, and the hot air The intermediate moving to the right is blown and dried, and the microporous filter membrane 167 can block the intermediate to prevent the intermediate from entering the exhaust pipe 162 and the intake pipe 161. As the intermediate continues to move to the right to above the opening 165, the dried intermediate falls downward through the opening 165 into the storage tank 2 for storage. The intermediate in the storage tank 2 falls into the collecting hopper 11 and is blocked by the fixed porous disk 13 and the rotating porous disk 14. When the storage tank 2 is filled with an appropriate amount of dry intermediate, the suction pump 3 is turned off, and the intermediate stops being discharged into the storage tank 2. The storage tank 2 continues to store the dried intermediate. When the required amount of intermediate needs to be taken out for use, the stepper motor 12 is first started to reverse, and the stepper motor 12 reverses and is driven by the synchronous belt assembly Drive the spiral conveying plate 122 to reverse, and then start the drive motor 15. The drive motor 15 drives the rotating porous disk 14 to rotate through the synchronous belt assembly. When the rotating porous disk 14 rotates and corresponds to the holes of the fixed porous disk 13, the rotating porous disk 14 is connected to the fixed porous disk 13, and the drive motor 15 is turned off. At this time, the dry intermediate in the storage tank 2 falls into the cylinder 4 through the rotating porous disk 14 and the fixed porous disk 13. The intermediate in the cylinder 4 falls onto the weighing disk 5 and is blocked by the electric opening and closing plate 6. The weighing disk 5 weighs the fallen intermediate. At this time, the falling intermediate is still in a dry environment. When the fallen intermediate reaches the required weight, start the drive motor 15 and drive the rotating porous disk 14 to rotate through the synchronous belt assembly. The rotating porous disk 14 rotates so that the holes are not in correspondence with the holes of the fixed porous disk 13, and the intermediate in the storage tank 2 stops being discharged into the cylinder 4. At this time, the discharged intermediate is separated from the remaining intermediate, and the electric control valve 8 can be started to open, and the electric control valve 8 stops blocking the discharge pipe 7. Then the electric opening and closing plate 6 is started to rotate ninety degrees to open, and the electric opening and closing plate 6 stops blocking the intermediate in the weighing pan 5. The intermediate on the weighing pan 5 falls downward into the discharge pipe 7, and the discharge pipe 7 discharges the intermediate for collection. Due to the action of the fixed porous disk 13 and the rotating porous disk 14, the discharged intermediate is separated from the remaining intermediate, which can prevent water vapor from entering the storage tank 2 and causing the remaining intermediate to become wet, thereby improving the intermediate storage effect. When all the intermediate in the weighing pan 5 is discharged,Start the air supply pump 9 to discharge nitrogen into the tee pipe 10. The nitrogen in the tee pipe 10 is discharged into the lower inner part of the cylinder 4 and the collecting hopper 11. The flow of nitrogen dries the lower inner part of the cylinder 4 and the collecting hopper 11. When the lower inner part of the cylinder 4 and the collecting hopper 11 are dry, turn off the air supply pump 9, and the discharge of nitrogen into the lower inner part of the cylinder 4 and the collecting hopper 11 stops. Then start the electric opening and closing plate 6 to rotate 90 degrees in the opposite direction to reset and seal the discharge end of the weighing pan 5. Then start the electric control valve 8 to close it.

[0036] See also Figure 8 As shown, the drying and storage equipment for fluoxetine pharmaceutical intermediates also includes a stirring assembly installed on the storage tank 2, the stirring assembly includes a rotating frame 17, a heating rod 171 and a driving assembly, and two rotating frames 17 are rotatably connected to the upper front side of the storage tank 2, and the rear sides of the upper and lower rotating frames 17 are symmetrically fixed with heating rods 171. When the heating rods 171 rotate, the heating rods 171 can achieve further drying of the intermediate, and a driving assembly is provided between the rotating frame 17 and the storage tank 2. When the driving assembly is in operation, the driving assembly can drive the rotating frame 17 to rotate; the driving assembly includes a worm gear 172, a dual-axis motor 173 and a worm 174. The front sides of the upper and lower rotating frames 17 are fixedly covered with worm gears 172, and a dual-axis motor 173 is installed on the upper outer front side of the storage tank 2. The output shaft ends of the upper and lower sides of the dual-axis motor 173 are fixed with worms 174, and the upper and lower worms 174 are respectively engaged with the upper and lower worm gears 172.

[0037] See also Figure 9 and Figure 10 As shown, the drying and storage device for fluoxetine pharmaceutical intermediates also includes a sealing assembly installed between the cylinder 4 and the fixed porous disk 13, the sealing assembly includes an airbag 18, a fixing frame 181, a cylinder 182, a cylinder body 183, a piston rod 184, an air guide tube 185 and a connecting tube 186, and five airbags 18 are embedded and fixed at even intervals along the circumference of the top of the fixed porous disk 13. When the airbags 18 are inflated, the airbags 18 can seal the holes of the rotating porous disk 14. The bottoms of the five airbags 18 are connected. It is connected to an air guide pipe 185, which is fixed through the fixed porous disk 13. A fixing frame 181 is fixed to the upper left side of the cylinder 4. A cylinder body 183 is fixed to the right side of the fixing frame 181. A piston rod 184 is slidably connected to the inside of the cylinder body 183. A connecting pipe 186 is connected to the middle of the right side of the cylinder body 183. The tail end of the connecting pipe 186 is fixedly connected to the middle of the air guide pipe 185. A cylinder 182 is fixed to the left side of the fixing frame 181. The end of the telescopic rod of the cylinder 182 is fixedly connected to the left end of the piston rod 184.

[0038] When the dried intermediate is stored in the storage tank 2, the intermediate contacts the heating rod 171. When the intermediate is stored for a long time, the heating rod 171 is first started, and then the dual-axis motor 173 is started. The dual-axis motor 173 drives the upper and lower worms 174 to rotate. The worms 174 drive the worm gear 172 to rotate. The worm gear 172 drives the rotating frame 17 to rotate. The rotating frame 17 drives the heating rod 171 to rotate. The rotation of the heating rod 171 stirs the intermediate in the storage tank 2, and the heating rod 171 also heats and dries the stirred intermediate. When the intermediate is dried for a suitable time, the heating rod 171 is turned off, and the dual-axis motor 173 is also turned off. The dual-axis motor 173 stops driving the worm 174, the worm 174 stops driving the worm gear 172, the worm gear 172 stops driving the rotating frame 17, and the rotating frame 17 stops rotating the heating rod 171. In this way, water droplets can be prevented from forming in the storage tank 2 on a southerly windy day, which may cause the intermediate to become wet, thereby ensuring the dryness of the intermediate.

[0039] When the intermediate on the weighing plate 5 reaches the required amount, the driving motor 15 is started, so that the rotating porous plate 14 rotates and is not connected with the fixed porous plate 13, and then the cylinder 182 is started, and the telescopic rod of the cylinder 182 is extended to drive the piston rod 184 to move to the right, and the piston rod 184 moves to the right to push the air in the cylinder body 183 into the connecting pipe 186, and the air in the connecting pipe 186 is discharged into the air guide pipe 185, and the air in the air guide pipe 185 is discharged into the air bag 18, and the air bag 18 continuously expands to seal the hole of the rotating porous plate 14. At this time, the intermediate in the storage tank 2 will not enter the rotating porous plate 14 and the fixed porous plate 13. In the gap between the fixed porous disks 13, the air cylinder 182 is closed, the piston rod 184 stops moving to the right, and the air bag 18 stops expanding. When it is necessary to discharge the intermediate in the storage tank 2 into the cylindrical body 4, the air cylinder 182 is first started, and the telescopic rod of the cylinder 182 is shortened to drive the piston rod 184 to move to the left and reset. The piston rod 184 moves to the left and resets to pump the air in the air bag 18 back into the cylinder body 183 through the connecting pipe 186 and the air guide pipe 185. As the air is pumped out, the air bag 18 continuously contracts and stops sealing the hole of the rotating porous disk 14, so that the rotating porous disk 14 can be rotated and connected to the fixed porous disk 13. In this way, the intermediate can be prevented from entering the gap between the rotating porous disk 14 and the fixed porous disk 13 and affecting the rotation of the rotating porous disk 14, thereby ensuring the smooth rotation of the rotating porous disk 14.

[0040] See also Figure 11 As shown, the drying and storage equipment for fluoxymethane pharmaceutical intermediates further includes a corrugated cover 19 . The corrugated cover 19 is connected between the discharge end of the collecting hopper 11 and the feed end of the discharge pipe 7 . The corrugated cover 19 can block the flying intermediates.

[0041] When the intermediate in the weighing pan 5 is discharged, the intermediate is discharged into the discharge pipe 7 through the corrugated cover 19. The corrugated cover 19 can guide the intermediate discharged from the weighing pan 5. In this way, the intermediate in the weighing pan 5 can be accurately discharged into the discharge pipe 7 for collection.

[0042] Although the present invention has been described in detail with reference to the above embodiments, it will be apparent to those skilled in the art from this disclosure that various changes or modifications may be made to the present invention without departing from the principle and spirit of the invention as defined in the claims.

Claims

1. A drying and storage device for a fluoxetine pharmaceutical intermediate, comprising a frame (1) and a storage tank (2) fixedly connected to the top of the frame (1), a suction pump (3) installed on the top of the frame (1), a cylinder (4) fixedly connected vertically to the frame (1), a weighing plate (5) provided inside the cylinder (4), and an electric opening and closing plate (6) installed on the weighing plate (5), wherein the device is characterized in that: The invention also includes a drying component arranged on the storage tank (2), the drying component is connected to the discharge end of the suction pump (3), and is used to transport and dry the intermediate. The bottom of the cylinder (4) is connected to a discharge pipe (7), and an electric control valve (8) is installed on the discharge pipe (7). A collecting hopper (11) is fixedly connected to the inner side of the cylinder (4) along the circumferential direction, and a fixed porous disk (13) is fixedly connected to the inner side of the collecting hopper (11) along the circumferential direction. The top of the fixed porous disk (13) is rotatably connected to a rotating porous disk (14). A driving motor (15) is installed on the cylinder (4), and the output shaft of the driving motor (15) is connected to the rotating The porous discs (14) are connected to each other in the circumferential direction by a synchronous belt assembly. The driving motor (15) is used to drive the rotating porous disc (14) to rotate. The rotating porous disc (14) rotates to open and close the fixed porous disc (13). When opened, the intermediate falls downward into the weighing disc (5). When closed, the intermediate stops falling downward so that the discharged intermediate is separated from the remaining intermediate. Then, the intermediate on the weighing disc (5) is completely discharged. A conveying assembly is provided between the cylinder (4) and the collecting hopper (11) for driving the intermediate to be uniformly conveyed downward.

2. A drying and storage device for a fluoxetine pharmaceutical intermediate according to claim 1, characterized in that: The conveying assembly includes a fixed plate (121) fixed to the inner side of the collecting hopper (11), a spiral conveying plate (122) rotatably connected to the fixed plate (121) and in contact with the inner side of the collecting hopper (11), and is used to drive the intermediate to move downward for conveying. A stepper motor (12) is installed on the cylinder (4), and the output shaft of the stepper motor (12) and the spiral conveying plate (122) are connected by a synchronous belt assembly.

3. A drying and storage device for a fluoxetine pharmaceutical intermediate according to claim 1, characterized in that: The drying component includes a fixed pipe (16) fixedly connected to the storage tank (2), the end of the fixed pipe (16) is connected to the discharge end of the suction pump (3), an opening (165) is opened on the right side of the bottom of the fixed pipe (16) for discharging the dried intermediate, an exhaust pipe (162) is fixedly connected to the storage tank (2), the end of the exhaust pipe (162) is fixedly connected to the fixed pipe (16), an air intake pipe (161) is fixedly connected to the storage tank (2), the end of the air intake pipe (161) is fixedly connected to the fixed pipe (16), a spiral shaft (164) is rotatably connected between the fixed pipe (16) and the storage tank (2), and is used to drive the intermediate to move to the right for uniform drying, a servo motor (163) is installed on the storage tank (2), the end of the output shaft of the servo motor (163) is fixedly connected to the end of the spiral shaft (164), and a blocking component is provided on the fixed pipe (16) for blocking the intermediate.

4. A drying and storage device for a fluoxetine pharmaceutical intermediate according to claim 3, characterized in that: The blocking assembly includes a frame (166) symmetrically fixed to the inner side of the fixed tube (16), a microporous filter membrane (167) fixed to the inner side of the frame (166), and the microporous filter membrane (167) corresponds to the exhaust pipe (162) and the intake pipe (161) and is used to block the intermediate body.

5. A drying and storage device for a fluoxetine pharmaceutical intermediate according to claim 1, characterized in that: The drying and storage device for fluoxetine pharmaceutical intermediates further comprises a stirring assembly, which comprises a rotating frame (17) rotatably connected to the storage tank (2), a heating rod (171) being symmetrically fixed to the rotating frame (17) for further drying the intermediate, and a driving assembly being provided between the rotating frame (17) and the storage tank (2) for driving the rotating frame (17) to rotate.

6. A drying and storage device for a fluoxetine pharmaceutical intermediate according to claim 5, characterized in that: The driving assembly includes a worm gear (172) fixedly mounted on the rotating frame (17), a dual-axis motor (173) is mounted on the storage tank (2), and a worm (174) meshing with the worm gear (172) is fixedly connected to the end of the output shaft of the dual-axis motor (173).

7. The drying and storage equipment for fluoxetine pharmaceutical intermediate according to claim 1, characterized in that: The drying and storage device for fluoxetine pharmaceutical intermediates also includes a sealing component, which includes air bags (18) embedded and fixed to the top circumference of the fixed porous disk (13) at uniform intervals, and is used to seal the holes of the rotating porous disk (14). An air guide tube (185) is connected between the air bags (18), and the air guide tube (185) is fixedly passed through the fixed porous disk (13). A fixed frame (181) is fixedly connected to the inner side of the cylinder (4), and a cylinder (183) is fixedly connected to the inside of the fixed frame (181). A piston rod (184) is slidably connected to the inner side of the cylinder (183). A connecting pipe (186) fixedly connected to the air guide tube (185) is connected to the cylinder (183). A cylinder (182) is fixedly connected to the inside of the fixed frame (181), and the end of the telescopic rod of the cylinder (182) is fixedly connected to the end of the piston rod (184).

8. The drying and storage equipment for fluoxetine pharmaceutical intermediate according to claim 1, characterized in that: The dry storage device for fluoxycephalosporin pharmaceutical intermediates further comprises a corrugated cover (19) connected between the discharge end of the collecting hopper (11) and the feed end of the discharge pipe (7) for blocking the flying intermediates.

Images