Dissolution meter rotating shaft calibration device

Abstract

The invention belongs to the technical field of dissolution instrument calibration, and particularly relates to a dissolution instrument rotating shaft calibration device which comprises a laser displacement sensor for calibrating a shaft rod of a dissolution instrument and a perpendicularity calibration unit. The base body is detachably arranged at the cup opening of the dissolution cup through a limiting buckling assembly; the bending plate is arranged on the base body; the power assembly is arranged on the bending plate, is matched with the base body and is used for driving the bending plate to do circumferential rotation around the cup opening of the dissolution cup; the radial pushing assembly is used for arranging the laser displacement sensor or the perpendicularity calibration unit on the bending plate and pushing the laser displacement sensor or the perpendicularity calibration unit to move in the radial direction of the dissolution cup; according to the scheme, the laser displacement sensor and the perpendicularity calibration unit can be in an automatic state to calibrate the shaft lever, so that the calibration accuracy of the rotating shaft of the dissolution tester can be improved.

Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of dissolution apparatus calibration, and particularly relates to a rotating shaft calibration device for a dissolution apparatus. BACKGROUND

[0002] Dissolution is the dissolution rate and degree of an active pharmaceutical ingredient from a tablet, a capsule or a granule preparation under a specified condition. It is a simple in-vitro test method for simulating the disintegration and dissolution of an oral solid preparation in a gastrointestinal tract, and is an important index for evaluating the quality of an oral solid preparation of a drug.

[0003] The existing rotating shaft or shaft rod of a dissolution apparatus is calibrated by mainly using a dial gauge which can be assembled on the shaft rod to calibrate the coaxiality of the rotating shaft. The verticality of the rotating shaft is calibrated by directly using a handheld verticality calibration unit to adhere to the rod body of the rotating shaft to calibrate the verticality parameters. However, when the verticality of the rotating shaft is calibrated, the verticality calibration unit needs to rotate at least 90 degrees around the rod body of the rotating shaft. Therefore, if the verticality calibration unit is inclined or deviated when adhering to the shaft rod of the rotating shaft, the accuracy of the verticality calibration of the rotating shaft will be affected, and the normal use of the dissolution apparatus will be affected. For the calibration of the swing degree and other parameters of the rotating shaft, a laser displacement sensor is mainly placed on the table surface of the dissolution apparatus, and the laser of the laser displacement sensor is shot on the rotating shaft to calibrate the swing degree parameters of the rotating shaft. Obviously, if the laser displacement sensor is not placed flat or the laser shot on the rotating shaft is not accurate, the accuracy of the swing degree calibration of the rotating shaft will be affected. SUMMARY

[0004] To solve the above technical problems, the application is realized by the following technical scheme: The application is a rotating shaft calibration device for a dissolution apparatus, which comprises a laser displacement sensor and a verticality calibration unit for calibrating the shaft rod of the dissolution apparatus. The base body is detachably arranged at the cup opening of the dissolution cup through a plurality of limiting buckle assemblies. The bending plate is arranged on the base body. The power assembly is arranged on the bending plate and cooperates with the base body to drive the bending plate to rotate around the cup opening of the dissolution cup. The radial pushing assembly is used to arrange the laser displacement sensor or the verticality calibration unit on the bending plate and push the laser displacement sensor or the verticality calibration unit to move in the radial direction of the dissolution cup.

[0005] In the embodiment, each set of the limiting buckle assembly comprises a bottom support plate arranged on the top boss of the dissolution cup, an arc-shaped plate arranged on the lower surface of the bottom support plate and located in the dissolution cup, a square frame seat arranged on the lower surface of the bottom support plate and located outside the dissolution cup, a clamping block movably arranged in the square frame seat and used for clamping the boss, and a first screw threadedly connected to the square frame seat and used for driving the clamping block to move. Preferably, the wall surface of the bottom support plate and the arc-shaped plate, which is in contact with the dissolution cup, is provided with a rubber layer.

[0006] In the embodiment, the base body comprises: an arc-shaped strip symmetrically arranged on the upper surface of the boss through two sets of bottom support plates; a butt joint square hole opened at both ends of the arc-shaped strip; an arc-shaped connecting strip movably arranged in the two opposite butt joint square holes respectively; a countersunk hole penetratingly opened on the top surface of the butt joint square hole; a locking hole opened on the bottom surface of the butt joint square hole and corresponding to the countersunk hole; and a locking bolt movably arranged in the countersunk hole, and the shank of the locking bolt is threadedly connected with the locking hole through the through hole opened on the arc-shaped connecting strip. Preferably, the outer circumferential surface of the butt joint square hole is penetratingly provided with a butt joint notch, and the height dimension of the butt joint notch is the same as that of the butt joint square hole.

[0007] In the embodiment, the outer circumferential surface of the butt joint square hole is penetratingly provided with a butt joint notch, and the height dimension of the butt joint notch is the same as that of the butt joint square hole; the outer circumferential surface of the arc-shaped strip away from the butt joint notch is formed with a long tooth, and the outer wall surface of the butt joint notch is symmetrically provided with a short tooth upward and downward; the outer circumferential surface of the arc-shaped connecting strip is formed with an arc-shaped protruding strip matched with the butt joint notch, and the outer circumferential surface of the arc-shaped protruding strip is formed with a middle tooth; the distance between the adjacent two short teeth, the middle tooth and the long tooth is the same, the length of the middle tooth is the same as the distance between the two short teeth upward and downward, and the shape of the middle tooth aligned with the two short teeth upward and downward is the same as that of the long tooth. The power assembly comprises a motor arranged on the bending plate and a gear connected with the output shaft of the motor; wherein the gears are in meshing transmission with the short tooth, the middle tooth and the long tooth.

[0008] In the embodiment, the power assembly further comprises a T-shaped guide groove opened on the inner circumferential surface of the arc-shaped strip, a T-shaped sliding strip movably arranged in the T-shaped guide groove, and a second screw connecting the T-shaped sliding strip and the vertical plate of the bending plate.

[0009] In the embodiment, the radial pushing assembly comprises a T-shaped straight line strip arranged on the horizontal plate of the bending plate, a straight line sliding strip movably sleeved on the T-shaped straight line strip, and an L-shaped support plate arranged on the straight line sliding strip and used for mounting the laser displacement sensor or the perpendicularity calibration unit. The straight slide is internally provided with a T-shaped cavity matched with the T-shaped straight strip, and the T-shaped cavity is in an open state towards the end of the shaft rod, and the other end is in a blocked state. When the bending plate is installed on the base body, the T-shaped straight strip is towards the center line direction of the dissolution cup.

[0010] In the embodiment, the radial pushing assembly further comprises a spring member arranged on the horizontal plate of the L-shaped support plate, a support plate arranged on the top of the spring member, a first threaded hole arranged on the support plate and aligned with the spring member, and a second threaded hole arranged on the horizontal plate of the L-shaped support plate and aligned with the first threaded hole. When the perpendicularity calibration unit is arranged on the support plate, it is connected with the first threaded hole through the fourth screw. When the laser displacement sensor is arranged on the support plate, it is connected with the second threaded hole through the fourth screw.

[0011] In the embodiment, the perpendicularity calibration unit comprises a protective box arranged outside the inclination sensor, a threading hole arranged on the wall of the protective box, and a semicircular groove arranged on the vertical side wall of the protective box. The protective box and the laser displacement sensor are both provided with through holes through which the fourth screw passes.

[0012] The present application has the following advantages: The laser displacement sensor and the perpendicularity calibration unit are detachably installed on the bending plate through the radial pushing assembly, and the bending plate is installed on the base body fixed at the cup opening of the dissolution cup, so that the bending plate can serve as the base or reference point of the laser displacement sensor and the perpendicularity calibration unit, so that the laser displacement sensor and the perpendicularity calibration unit can be in an automatic state to calibrate the shaft rod. The perpendicularity calibration unit installed on the bending plate can be closely attached to the shaft rod to be calibrated through the pushing of the radial pushing assembly, without the need for the operator to hold the perpendicularity calibration unit and the shaft rod, and the power assembly can drive the perpendicularity calibration unit to rotate 360° around the shaft rod, so that the perpendicularity calibration unit can rotate different angles around the shaft rod as needed to calibrate the perpendicularity of the shaft rod, thereby reducing the labor intensity of the operator.

[0013] Of course, implementing any product of the present application does not necessarily need to achieve all the advantages described above at the same time. BRIEF DESCRIPTION OF DRAWINGS

[0014] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following will briefly introduce the drawings needed to be used in the description of the embodiments. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can also be obtained by those skilled in the art without any creative effort based on these drawings.

[0015] Figure 1 The schematic diagram of the verticality calibration structure of the rotating shaft of the present embodiment; Figure 2 The schematic diagram of the swing degree calibration structure of the rotating shaft of the present embodiment; Figure 3 The assembly schematic diagram of the base body, the bending plate, the power assembly and the radial pushing assembly of the present embodiment; Figure 4 The structural schematic diagram of the limiting buckle assembly of the present embodiment; Figure 5 The structural schematic diagram of the base body of the present embodiment; Figure 6 The separation state diagram of the arc-shaped strip and the arc-shaped connecting strip of the present embodiment; Figure 7 The structural schematic diagram of the bending plate of the present embodiment; Figure 8 The exploded view of the radial pushing assembly of the present embodiment; Figure 9 The exploded view of the laser displacement sensor and the supporting plate of the present embodiment; Figure 10 The exploded view of the verticality calibration unit and the supporting plate of the present embodiment.

[0016] In the figure: 1, laser displacement sensor; 2, verticality calibration unit; 3, base body; 31, arc-shaped strip; 311, butt joint square hole; 312, counterbore; 313, locking hole; 314, butt joint notch; 315, T-shaped guide groove; 32, arc-shaped connecting strip; 33, locking bolt; 34, long tooth; 35, short tooth; 36, arc-shaped protruding strip; 37, middle tooth; 4, limiting buckle assembly; 41, bottom supporting plate; 42, arc-shaped plate; 43, square frame seat; 44, clamping block; 5, bending plate; 51, hidden sliding groove; 6, power assembly; 61, gear; 62, T-shaped sliding strip; 7, radial pushing assembly; 71, T-shaped straight line strip; 72, straight line sliding strip; 73, L-shaped supporting plate; 74, T-shaped cavity; 75, adjusting long groove; 76, spring part; 77, supporting plate; 78, first threaded hole; 79, second threaded hole; 8, protection box; 81, semicircular groove; 9, dissolution cup; 91, boss; 10, shaft. DETAILED DESCRIPTION

[0017] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative work fall within the scope of protection of the present application.

[0018] In the description of the present application, it should be understood that the terms "opening", "upper", "lower", "thickness", "top", "middle", "length", "inner", "periphery" and the like indicate the orientation or positional relationship, which are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the components or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation of the present application.

[0019] Please refer to Figures 1 to 3 As shown in the drawings, the present application is a dissolution apparatus shaft calibration device, which comprises a laser displacement sensor 1 and a perpendicularity calibration unit 2 for calibrating the shaft 10 of the dissolution apparatus; further comprising: a base body 3 which is detachably installed at the cup opening of the dissolution cup 9 through a plurality of sets of limiting buckle assemblies 4; a bending plate 5 installed on the base body 3; a power assembly 6 installed on the bending plate 5 and cooperating with the base body 3, for driving the bending plate 5 to rotate around the cup opening of the dissolution cup 9; and a radial displacement assembly 7 for installing the laser displacement sensor 1 or the perpendicularity calibration unit 2 on the bending plate 5, and pushing the laser displacement sensor 1 or the perpendicularity calibration unit 2 to move along the radial direction of the dissolution cup 9; It should be noted that the base body 3 is in the form of a circular ring, which can better match the cup opening of the dissolution cup 9, and then the circular ring-shaped base body 3 is installed at the cup opening of the dissolution cup 9 through the limiting buckle assembly 4, while the bending plate 5 can be assembled on the circular ring-shaped base body 3 through the power assembly 6, and the radial displacement assembly 7 can separately install the laser displacement sensor 1 or the perpendicularity calibration unit 2 on the bending plate 5, so that the laser displacement sensor 1 or the perpendicularity calibration unit 2 can be installed near the cup opening of the dissolution cup 9 with the horizontal plate of the bending plate 5 as the "reference surface", without causing the laser displacement sensor 1 or the perpendicularity calibration unit 2 to be used in a handheld manner or a simple support manner due to the lack of "base or reference point" for the installation of the laser displacement sensor 1 or the perpendicularity calibration unit 2 around the dissolution cup 9; For example, when the verticality calibration unit 2 is installed on the bending plate 5 through the radial push assembly 7, and the verticality of the shaft 10 needs to be calibrated, the verticality calibration unit 2 needs to be extended out of the bending plate 5, and then the radial push assembly 7 is pushed to move the verticality calibration unit 2 to the shaft 10, and the semicircular groove 81 of the verticality calibration unit 2 is attached to the shaft 10, and then the power assembly 6 drives the verticality calibration unit 2 to rotate around the shaft 10 to calibrate the verticality of the shaft 10. For example, when the swing degree of the shaft 10 needs to be calibrated, the laser displacement sensor 1 is installed on the bending plate 5 through the radial push assembly 7, and the radial push assembly 7 pushes the laser displacement sensor 1 to move radially at the cup opening of the dissolution cup 9, so that the distance between the laser displacement sensor 1 and the shaft 10 can be adjusted, preventing the laser displacement sensor 1 from being too far away from the shaft 10, so that the laser beam emitted by the laser displacement sensor 1 cannot accurately hit the shaft 10, and then the shaft 10 is rotated to calculate the difference between the maximum and minimum displacements, thereby measuring the swing degree of the shaft 10. The laser displacement sensor 1 and the verticality calibration unit 2 are detachably installed on the bending plate 5 through the radial push assembly 7, and the bending plate 5 is installed on the base body 3 fixed at the cup opening of the dissolution cup 9, so that the bending plate 5 can serve as the base or reference point of the laser displacement sensor 1 and the verticality calibration unit 2, enabling the laser displacement sensor 1 and the verticality calibration unit 2 to be in an automated state for calibration of the shaft 10. The verticality calibration unit 2 installed on the bending plate 5 can be tightly attached to the shaft 10 to be calibrated through the radial push assembly 7, without the need for an operator to manually hold the verticality calibration unit 2 against the shaft 10, and the power assembly 6 can drive the verticality calibration unit 2 to rotate 360° around the shaft 10, enabling the verticality calibration unit 2 to rotate around the shaft 10 at different angles as needed to calibrate the verticality of the shaft 10, which not only reduces the labor intensity of the operator, but also prevents the handheld verticality calibration unit 2 from being affected by the limited twisting angle of the operator's arm when rotating around the shaft 10, thereby affecting the accuracy of the verticality calibration of the shaft 10.

[0020] As a preferred embodiment of the present application, refer to Figure 1 , Figure 3 and Figure 4As shown, the limiting buckle assembly 4 includes a bottom support plate 41 arranged at the top boss 91 of the dissolution cup 9, an arc-shaped plate 42 arranged on the lower surface of the bottom support plate 41 and located inside the dissolution cup 9, a square frame seat 43 arranged on the lower surface of the bottom support plate 41 and located outside the dissolution cup 9, a clamping block 44 movably arranged in the square frame seat 43 for clamping to the boss 91, and a first screw threadedly connected to the square frame seat 43 and used to drive the clamping block 44 to move; It should be noted that the bottom support plate 41 and the arc-shaped plate 42 are integrally formed, and the wall surface where the bottom support plate 41 and the arc-shaped plate 42 are attached to the boss 91 is provided with a rubber layer to prevent the base body 3 from damaging the dissolution cup 9 when the base body 3 is installed to the upper cup opening of the dissolution cup 9, and the first screw connected with the square frame seat 43 is preferably a hexagonal handle screw; When it is necessary to install the base body 3 to the cup opening of the dissolution cup 9, the base body 3 is first placed above the boss 91 of the dissolution cup 9, at this time the bottom support plate 41 will be in contact with the upper surface of the boss 91, the arc-shaped plate 42 will be attached to the cup wall of the dissolution cup 9, and the transition gap formed between the square frame seat 43 and the arc-shaped plate 42 will cooperate with the radial thickness of the boss 91, then the first screw is twisted to make the first screw cooperate with the nut welded to the outer side of the square frame seat 43 to push the clamping block 44 in the square frame seat 43 to attach to the outer circle surface of the boss 91, the corresponding surface of the clamping block 44 and the boss 91 is an arc-shaped surface and is provided with a rubber layer, thereby facilitating the fixation of the base body 3 on the boss 91 of the dissolution cup 9, and achieving the support installation of the laser displacement sensor 1 and the perpendicularity calibration unit 2; Further, when the laser displacement sensor 1 is installed on the base body 3 through the bending plate 5, at this time the laser of the laser displacement sensor 1 can be debugged to see whether it hits the shaft 10, if not, the first screw on the outer side of the symmetrical bottom support plate 41 can be twisted to make the corresponding clamping block 44 below one of the bottom support plates 41 move outward in the square frame seat 43, while the other clamping block 44 symmetrically arranged will move towards the inside of the square frame seat 43, since the arc-shaped plate 42 and the inner wall of the dissolution cup 9 are attached and contacted through the rubber layer, therefore, as the one clamping block 44 moves towards the outer circle surface of the boss 91, at this time the arc-shaped plate 42 will move towards the inner wall of the dissolution cup 9, and the corresponding rubber layer will be compressed, while the other clamping block 44 will move away from the outer circle surface of the boss 91, at this time the arc-shaped plate 42 will move away from the inner wall of the dissolution cup 9, and the corresponding rubber layer will be released, thereby facilitating the adjustment of the position of the circular base body 3 in the dissolution cup 9, so that the laser of the laser displacement sensor 1 can accurately hit the shaft 10, thereby enabling the laser displacement sensor 1 to accurately calibrate the swing degree parameter of the shaft 10, and also enabling the radially moving perpendicularity calibration unit 2 to closely attach to the shaft 10; By reversing the first screw, the clamping block 44 moves away from the outer circle surface of the boss 91, which facilitates the disassembly of the base body 3 from the cup opening of the dissolution cup 9, thereby facilitating the calibration of the next dissolution tester shaft 10.

[0021] As a preferred embodiment of the present application, the dissolution tester is divided into a split type paddle shaft dissolution tester and a whole type rotating shaft dissolution tester, and is a multi-cup and multi-rod type, for example, an eight-cup and eight-rod type dissolution tester. The multiple shafts 10 of the multi-cup and multi-rod type dissolution tester need to be calibrated, so the base body 3 needs to be installed on the bosses 91 of the multiple dissolution cups 9 in sequence for the installation and use of the laser displacement sensor 1 or the verticality calibration unit 2. If the base body 3 is integrally arranged, the operator needs to frequently lift multiple shafts 10 to sequentially install the base body 3 on the bosses 91 of the multiple dissolution cups 9. This installation method not only affects the calibration efficiency of the shafts 10 of the multi-rod and multi-cup type dissolution tester, but also causes unnecessary waste of electrical energy due to the sequential lifting movement of the multiple shafts 10. The present application is designed as follows: Referring to FIGS. 3, Figure 5 and Figure 6 As shown, the base body 3 comprises: an arc-shaped strip 31 symmetrically arranged on the upper surface of the boss 91 by two groups of bottom supporting plates 41; a butt joint square hole 311 opened at both ends of the arc-shaped strip 31; an arc-shaped connecting strip 32 movably arranged at both ends of the butt joint square hole 311 of the two symmetric arc-shaped strips 31; a countersunk hole 312 through-opening on the top surface of the butt joint square hole 311; a locking hole 313 opened on the bottom surface of the butt joint square hole 311 and corresponding to the countersunk hole 312; and a locking bolt 33 movably arranged in the countersunk hole 312, and the shank of the locking bolt 33 is threadedly connected with the locking hole 313 through the through hole opened on the arc-shaped connecting strip 32. The outer circle surface of the butt joint square hole 311 is through-opened with a butt joint notch 314, and the height dimension of the butt joint notch 314 is equal to the height dimension of the butt joint square hole 311. It should be further explained that the butt joint square hole 311 and the butt joint notch 314 are both arc-shaped and opened at both ends of the arc-shaped strip 31. The locking bolt 33 connected to the arc-shaped connecting strip 32 is preferably an internal hexagonal cylindrical head screw, and the thickness of the cylindrical head is similar to the groove depth of the countersunk hole 312. The symmetric arc-shaped strips 31 and the symmetric arc-shaped connecting strips 32 are located on the same center although their arc lengths are different. The annular base body 3 is used as follows: When the shaft 10 of the split type paddle shaft dissolution tester needs to be calibrated, the base body 3 can be first spliced into a complete annular base body 3. The specific splicing method is as follows: First, the two ends of the two arc-shaped strips 31 are close to each other, and then the two arc-shaped connecting strips 32 are inserted into the corresponding end opening of the two arc-shaped strips 31 by radial pushing, and the two ends of the same arc-shaped connecting strip 32 are inserted into the docking gap 314 and the docking hole 311, at this time, the end face of the arc-shaped connecting strip 32 and the inner circle arc face are tightly closed to the hole wall of the docking hole 311, so that the through hole of the arc-shaped connecting strip 32 is aligned with the counterbore hole 312 and the locking hole 313, and then the inner hexagonal cylindrical head locking bolt 33 is inserted into the counterbore hole 312, so that the screw rod of the locking bolt 33 is screwed down through the through hole and the locking hole 313, and the cylindrical head of the locking bolt 33 is located in the counterbore hole 312, thereby facilitating the connection of the symmetrical arc-shaped strips 31 through the symmetrical arc-shaped connecting strips 32 to form a circular ring-shaped base body 3, and then the assembled base body 3 is installed on the boss 91 through the limiting buckle assembly 4, realizing the installation and use of the circular ring-shaped base body 3; When the shaft 10 of the dissolution tester needs to be calibrated, the base body 3 is installed and detached on the plurality of dissolution cups 9 as follows: When the base body 3 needs to be detached from the dissolution cup 9 corresponding to the calibrated shaft 10, first, the locking bolt 33 in the counterbore hole 312 of one of the arc-shaped connecting strips 32 is detached, and then the arc-shaped connecting strip 32 is pushed out of the corresponding end opening of the two arc-shaped strips 31 by radial pushing. At this time, the detached arc-shaped connecting strip 32 makes the corresponding end of the symmetrical arc-shaped strip 31 in a "gap" state, and the size of the "gap" is greater than the diameter of the shaft 10. Then, the limiting buckle assembly 4 is detached from the boss 91, at this time, the operator can pull the base body 3 upwards to make the limiting buckle assembly 4 higher than the boss 91, and then slowly pull the base body 3 radially to make the detached base body 3 can be separated from the shaft 10 through the "gap", thereby the base body 3 can be quickly detached from the dissolution cup 9 without completely separating the entire base body 3 into multiple arc-shaped strips 31; When it is necessary to install the disassembled base body 3 to the boss 91 of the next dissolution cup 9, at this time, the "notch" formed on the base body 3 is first matched with the shaft rod 10, and then the base body 3 is radially pushed to make the shaft rod 10 pass from the "notch" to the base body 3, and then the base body 3 is lowered to make the limiting buckle assembly 4 contact the boss 91, and then the separated arc-shaped connecting strip 32 is radially pushed into the "notch", so that the two ends of the arc-shaped connecting strip 32 are directly clamped into the butt joint hole 311 through the butt joint notch 314, and then the arc-shaped connecting strip 32 is fixed to the symmetrical arc-shaped strip 31 through the locking bolt 33, thereby the complete base body 3 is spliced, and the power assembly 6 can drive the verticality calibration unit 2 installed on the bent plate 5 to rotate around the base body 3, thereby the verticality calibration unit 2 can accurately calibrate the verticality of the shaft rod 10; Since the base body 3 is disassembled from the last dissolution cup 9 and transferred to the next dissolution cup 9 for installation, only one arc-shaped connecting strip 32 is disassembled from the two symmetrical arc-shaped strips 31 to form a "notch" on the base body 3 to facilitate the transition of the shaft rod 10, and then the arc-shaped connecting strip 32 is installed in the "notch", and the symmetrical arc-shaped strip 31 is connected by another arc-shaped connecting strip 32, so that the base body 3 is in a stable state, therefore, the installation of the arc-shaped connecting strip 32 is only to block the "notch" to facilitate the 360° rotation of the verticality calibration unit 2 installed on the bent plate 5 around the base body 3 driven by the power assembly 6, without affecting the overall precision of the spliced complete base body 3; The symmetrical arc-shaped strips 31 are connected by symmetrical arc-shaped connecting strips 32, rather than one arc-shaped connecting strip 32, on the one hand, when the bent plate 5 stops at the position of one arc-shaped connecting strip 32 and needs to be disassembled from the boss 91, the operator needs to drive the bent plate 5 to rotate and separate from the arc-shaped connecting strip 32 again, and then disassemble the arc-shaped connecting strip 32 from the symmetrical arc-shaped strips 31; on the other hand, when the base body 3 is installed on the boss 91 of the dissolution instrument with multiple cups and multiple rods, since one arc-shaped connecting strip 32 is located on the inner side of the boss 91, the base body 3 cannot be quickly disassembled from the boss 91; The base body 3 is spliced by two symmetrical arc-shaped strips 31 and two symmetrical arc-shaped connecting strips 32, which can be installed on the dissolution cup 9 of the dissolution instrument with split shafts and quickly assembled on the dissolution cup 9 of the dissolution instrument with integral shafts, so that the operator does not need to frequently lift multiple shaft rods 10 to install the base body 3 on the bosses 91 of multiple dissolution cups 9, thereby improving the calibration efficiency of the shaft rod 10 of the dissolution instrument with multiple rods and multiple cups.

[0022] Further limited, in order to facilitate the power assembly 6 drive installed on the bending plate 5 on the base body 3 after the stable rotation of the verticality calibration unit 2, to realize the verticality calibration unit 2 in the automatic state of the shaft 10 parameter calibration, the scheme is designed as follows: Referring to Figure 3 , Figure 5 and Figure 6 , the outer circle surface of the arc-shaped connecting strip 32 is formed with an arc-shaped protruding strip 36 matched with the butt joint gap 314, and the outer circle surface of the arc-shaped protruding strip 36 is formed with a middle tooth 37; the distance between the adjacent two short teeth 35, the middle tooth 37 and the long tooth 34 is the same, and the length of the middle tooth 37 is the same as the distance between the upper and lower two short teeth 35, and the shape of the middle tooth 37 aligned with the upper and lower two short teeth 35 is the same as that of the long tooth 34; Specifically, when the arc-shaped connecting strip 32 is pushed into the butt joint hole 311, the arc-shaped protruding strip 36 is simultaneously pushed into the butt joint gap 314 at this time, and since the thickness of the arc-shaped protruding strip 36 is the same as that of the arc-shaped connecting strip 32, the middle tooth 37 provided on the outer circle surface of the arc-shaped protruding strip 36 will be aligned with the short tooth 35 at the butt joint gap 314, so that the length formed by the two is the same as the length formed by the long tooth 34, and then when the gear 61 of the power assembly 6 is driven by the motor to rotate around the assembled base body 3, the teeth of the gear 61 will be engaged with the long tooth 34 and the aligned middle tooth 37 and short tooth 35 formed on the outer circle surface of the base body 3, thereby facilitating the bending plate 5 to drive the verticality calibration unit 2 to rotate; Since the arc-shaped connecting strip 32 is completely inserted into the corresponding two butt joint holes 311, when the gear 61 rotates to the arc-shaped connecting strip 32, the middle tooth 37 formed on the outer circle surface of the arc-shaped protruding strip 36 will also be engaged with the gear 61 at this time, thereby facilitating the bending plate 5 to be driven by the power assembly 6 to rotate around the spliced base body 3 by 360°, preventing the spliced base body 3 from being connected by other connecting members, so that the gear 61 cannot accurately engage with the teeth formed on the outer circle surface of the spliced base body 3, thereby affecting the 360° rotation of the verticality calibration unit 2 on the base body 3, and further affecting the calibration of the verticality calibration unit 2 on the shaft 10; The two symmetrical arc-shaped strips 31 are connected by the symmetrical arc-shaped connecting strips 32, and the middle teeth 37 formed on the outer arc surface of the arc-shaped connecting strips 32 can mesh with the gear 61 and align with the short teeth 35 on the outer surface of the butt joint gap 314 to form the same structure as the long teeth 34, so that the meshing gear 61 can be stably and safely transferred from the arc-shaped connecting strip 32 to the arc-shaped strip 31, preventing the existing two arc-shaped strips 31 from being connected by the cooperation of the upper and lower connecting plates and bolts or other connection methods, which causes the gear 61 to fail to accurately mesh with the teeth formed on the outer surface of the base body 3, or causes the bending plate 5 to fail to be attached to the upper surface of the base body 3 to rotate, thereby affecting the accurate support and installation of the bending plate 5 on the verticality calibration unit 2.

[0023] As a preferred embodiment of the present application, referring to Figure 3 and Figure 7 , the power assembly 6 includes a motor mounted on the bending plate 5 and a gear 61 connected to the output shaft of the motor; wherein the gear 61 meshes with the short teeth 35, the middle teeth 37 and the long teeth 34; the power assembly 6 further includes a T-shaped guide groove 315 opened in the inner surface of the arc-shaped strip 31, a T-shaped sliding strip 62 movably mounted in the T-shaped guide groove 315, and a second screw connecting the T-shaped sliding strip 62 and the vertical plate of the bending plate 5; It should be noted that the motor is preferably a servo motor and is fixed on the upper surface of the horizontal plate of the bending plate 5 and hidden in the box body with the circuit board installed, the height of the gear 61 matches the thickness of the base body 3, so that the gear 61 can mesh with the middle teeth 37, the upper and lower symmetrical short teeth 35, the mutually aligned middle teeth 37 and short teeth 35, and the long teeth 34, the T-shaped sliding strip 62 and the vertical plate of the bending plate 5 are both arc-shaped structures, and the second screw is preferably a hexagonal handle screw or other shaped screw; When the bending plate 5 needs to be installed on the base body 3, the horizontal plate of the bending plate 5 is placed on the upper surface of the base body 3 first, ensuring that the teeth of the gear 61 mesh with the long teeth 34 formed on the outer surface of the arc-shaped strip 31, and the vertical plate of the bending plate 5 is attached to the inner surface of the arc-shaped strip 31, then the second screw on the outer surface of the vertical plate is twisted to be threadedly connected to the T-shaped sliding strip 62, thereby facilitating the installation of the bending plate 5 on the upper surface of the base body 3; The T-shaped slide 62 is slidably arranged in the T-shaped guide groove 315, so as to drive the bending plate 5 to rotate around the base body 3 without interfering with the gear 61 and the tooth engagement, and the T-shaped slide 62 can only slide in the T-shaped guide groove 315 and cannot be separated from the T-shaped guide groove 315, so that the connection between the bending plate 5 and the T-shaped slide 62 can limit the vertical rotation of the bending plate 5, prevent the bending plate 5 from being separated from the base body 3 during the rotation of the bending plate 5 on the base body 3, and ensure the accurate engagement between the gear 61 and the tooth.

[0024] As a preferred embodiment of the present application, referring to Figures 7 to 10 As shown in the figure, the radial displacement assembly 7 comprises a T-shaped straight line 71 arranged on the horizontal plate of the bending plate 5, a straight slide 72 movably sleeved on the T-shaped straight line 71, and an L-shaped support plate 73 arranged on the straight slide 72 and used for mounting the laser displacement sensor 1 or the verticality calibration unit 2. The straight slide 72 is internally provided with a T-shaped cavity 74 matched with the T-shaped straight line 71, and the end of the T-shaped cavity 74 facing the shaft 10 is open, and the other end is closed. The top wall of the T-shaped cavity 74 is provided with an adjusting long slot 75 for the third screw to move, so as to fix the straight slide 72 on the T-shaped straight line 71. When the bending plate 5 is mounted on the base body 3, the T-shaped straight line 71 faces the center line direction of the dissolution cup 9. It should be noted that if the laser displacement sensor 1 needs to be mounted on the bending plate 5, the laser displacement sensor 1 can be first mounted on the L-shaped support plate 73, then the open end of the T-shaped cavity 74 provided on the straight slide 72 is aligned with the T-shaped straight line 71, and then the straight slide 72 is pushed to slide along the T-shaped straight line 71, so that the L-shaped support plate 73 is synchronously slid to the upper side of the bending plate 5, and then the inner end of the L-shaped support plate 73 is adjusted to be flush with the vertical plate of the bending plate 5 or slightly protrude outward from the vertical plate according to the size of the laser displacement sensor 1, and then the third screw is connected through the adjusting long slot 75 and the threaded hole provided on the T-shaped straight line 71, and the third screw and the gasket are matched, so as to fix the straight slide 72 on the T-shaped straight line 71, and then the laser displacement sensor 1 is mounted on the bending plate 5 through the L-shaped support plate 73, so as to realize the calibration of the shaft 10. If the verticality calibration unit 2 needs to calibrate the verticality of the shaft 10, the verticality calibration unit 2 can be installed on the L-shaped support plate 73 first, and then the linear slide 72 is pushed. Since the length of the linear slide 72 is greater than the radius of the base body 3 when adjusted to the maximum state, it is guided by the T-shaped linear strip 71 to move the verticality calibration unit 2 to the outer ring surface of the shaft 10, thereby facilitating the accurate fitting of the verticality calibration unit 2 with the shaft 10. Since the linear slide 72 is matched with the T-shaped linear strip 71 through the T-shaped cavity 74, the linear slide 72 can be vertically limited to prevent the gravity of the verticality calibration unit 2 from causing the end of the linear slide 72 away from the verticality calibration unit 2 to be raised, thereby affecting the stable and accurate fitting of the verticality calibration unit 2 with the shaft 10.

[0025] By adjusting the third screw on the long groove 75 in the reverse direction, the linear slide 72 and the T-shaped linear strip 71 can be separated from the fixing, thereby facilitating the movement of the linear slide 72 to adjust the position of the laser displacement sensor 1.

[0026] Further limited, in order to make the verticality calibration unit 2 accurately fit the shaft 10 with different inclination angles, realize the verticality calibration of the shaft 10 with different inclination angles, thereby expanding the verticality calibration range of the verticality calibration unit 2 to the shaft 10, and at the same time, without affecting the accurate installation of the laser displacement sensor 1 on the L-shaped support plate 73; Referring to Figures 7 to 10 As shown, the radial pushing assembly 7 further comprises a spring member 76 arranged on the horizontal plate of the L-shaped support plate 73, a support plate 77 arranged on the top of the spring member 76, a first threaded hole 78 opened on the support plate 77 and aligned with the spring member 76, and a second threaded hole 79 opened on the horizontal plate of the L-shaped support plate 73 and aligned with the first threaded hole 78; When the verticality calibration unit is arranged on the support plate 77, it is connected with the first threaded hole 78 through the fourth screw; When the laser displacement sensor is arranged on the support plate 77, it is connected with the second threaded hole 79 through the fourth screw; It should be noted that the spring member 76, the first threaded hole 78 and the second threaded hole 79 are all 4, and are close to the four corners of the support plate 77, and the hole diameters of the first threaded hole 78 and the second threaded hole 79 are smaller than the inner diameter of the spring member 76; When it is needed to install the laser displacement sensor 1 on the L-shaped support plate 73, at this time, the fourth screws of the longer star-shaped handle are first inserted into the through holes of the laser displacement sensor 1, and the number of through holes is preferably 4, then the laser displacement sensor 1 is placed on the support plate 77, and then the fourth screws on the laser displacement sensor 1 are rotated in sequence, so that the shanks of the fourth screws are screwed into the second threaded holes 79 through the first threaded holes 78 and the spring members 76, so that the fourth screws can not only stably install the laser displacement sensor 1 on the support plate 77, but also fix the support plate 77 to the L-shaped support plate 73 through the fourth screws, so that the support plate 77 in a fixed state can safely and stably support the laser displacement sensor 1, preventing the laser displacement sensor 1 from being installed on the support plate 77 elastically supported by the spring members 76, and the support plate 77 from shaking on the L-shaped support plate 73 when the straight slide bar 72 is installed by sliding on the T-shaped straight bar 71, thereby affecting the firmness and stability of the laser displacement sensor 1 fixedly installed on the bending plate 5 by the radial pushing assembly 7. When it is needed to install the perpendicularity calibration unit 2 on the L-shaped support plate 73, at this time, the fourth screws of the shorter star-shaped handle are first inserted into the through holes of the perpendicularity calibration unit 2, then the perpendicularity calibration unit 2 is placed on the support plate 77, and then the fourth screws on the perpendicularity calibration unit 2 are pressed, so that the shanks of the fourth screws are aligned with the first threaded holes 78, then the fourth screws are twisted to be screwed into the first threaded holes 78, and when the shanks of the fourth screws are flush with the bottoms of the first threaded holes 78, the twisting of the fourth screws is stopped, so that the perpendicularity calibration unit 2 is installed on the support plate 77 only through the fourth screws. When the straight slide bar 72 moves along the T-shaped straight bar 71, the perpendicularity calibration unit 2 installed on the support plate 77 moves towards the shaft 10, and when the semicircular groove 81 formed on the perpendicularity calibration unit 2 is attached to the shaft 10, if the shaft 10 is in an inclined state at this time, the moving perpendicularity calibration unit 2 will first make one part of the groove wall of the semicircular groove 81 contact the shaft 10, then the operator continues to push the straight slide bar 72, at this time, the moving force of the straight slide bar 72 acts on the perpendicularity calibration unit 2 through the L-shaped support plate 73, the spring member 76 and the support plate 77, so that the semicircular groove 81 on the perpendicularity calibration unit 2 continues to attach to the shaft 10, and because the support plate 77 is elastically supported on the horizontal plate of the L-shaped support plate 73 by the spring member 76 at this time, the continued movement of the perpendicularity calibration unit 2 will cause it to have a certain inclination, for example, the upper part of the semicircular groove 81 contacts the shaft 10 first, then as the perpendicularity calibration unit 2 continues to move, it will produce a backward inclination to make the semicircular groove 81 contact the shaft 10, thereby facilitating accurate detection and processing of the shaft 10 in different inclined states.

[0027] Referring to Figure 9 and Figure 10 As shown in the figure, the verticality calibration unit 2 comprises a protective box 8 installed outside the tilt sensor, a threading hole opened on the wall of the protective box 8, and a semicircular groove 81 opened on the vertical side wall of the protective box 8; wherein the protective box 8 and the laser displacement sensor 1 are both provided with through holes for the fourth screw to pass through. It should be noted that the tilt sensor is installed on the L-shaped support plate 73 through the protective box 8, and the semicircular groove 81 is opened on the wall surface of the protective box 8 close to the center line of the dissolution cup 9, so that the vertical wall surface of the protective box 8 is accurately fitted with the shaft 10, and the protective box 8 can not only protect the tilt sensor, but also does not need to open a semicircular groove 81 on the outer wall of the body of the tilt sensor, so as not to cause damage to the outer wall of the body of the tilt sensor; and the through holes opened on the protective box 8 and the laser displacement sensor 1 are convenient for the screw to pass through, and then convenient for installation on the support plate 77.

[0028] In the description of the present specification, the description of the terms "one embodiment", "example", "specific example" and the like means that the specific features, structures, materials or characteristics described in connection with the embodiment or example are contained in at least one embodiment or example of the present application. In the present specification, the illustrative description of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0029] The preferred embodiments of the application disclosed above are only used to help explain the application. The preferred embodiments do not describe all the details and limit the application to the specific embodiments described. Obviously, many modifications and changes can be made according to the content of the present specification. The present specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the application, so that those skilled in the art can well understand and utilize the application. The application is limited only by the claims and their full scope and equivalents.

Claims

1. A dissolution apparatus spindle calibration apparatus comprising a laser displacement sensor and a perpendicularity calibration unit for calibration of a dissolution apparatus spindle; characterized in that, Also comprising: a base body which is detachably installed at the cup mouth of the dissolution cup through a plurality of sets of limiting buckle assembly; a bending plate which is installed on the base body; a power assembly which is installed on the bending plate and cooperates with the base body to drive the bending plate to rotate around the cup mouth of the dissolution cup; and a radial pushing assembly which is used to install the laser displacement sensor or the perpendicularity calibration unit on the bending plate and push the laser displacement sensor or the perpendicularity calibration unit to move along the radial direction of the dissolution cup.

2. The rotation shaft calibration device of the dissolution tester according to claim 1, wherein each set of the limiting buckle assembly comprises a bottom support plate installed at the top boss of the dissolution cup, an arc-shaped plate placed on the lower surface of the bottom support plate and located inside the dissolution cup, a square box seat placed on the lower surface of the bottom support plate and located outside the dissolution cup, a clamping block movably placed in the square box seat for clamping the boss, and a first screw threadedly connected to the square box seat and used to drive the clamping block to move; wherein the wall surface of the bottom support plate and the arc-shaped plate which is in contact with the dissolution cup is provided with a rubber layer.

3. The rotation shaft calibration device of the dissolution tester according to claim 2, wherein the base body comprises: an arc-shaped strip which is symmetrically installed on the upper surface of the boss through two sets of bottom support plates; a butt joint square hole which is opened at both ends of the arc-shaped strip; an arc-shaped connecting strip which is movably installed in two opposite butt joint square holes respectively; a countersunk hole which is opened through the top surface of the butt joint square hole; a locking hole which is opened on the bottom surface of the butt joint square hole and corresponds to the countersunk hole; and a locking bolt which is movably placed in the countersunk hole, and the shank of the locking bolt is threadedly connected with the locking hole through the through hole opened on the arc-shaped connecting strip; wherein the outer ring surface of the butt joint square hole is opened through a butt joint notch, and the height dimension of the butt joint notch is the same as that of the butt joint square hole.

4. The rotation shaft calibration device of the dissolution tester according to claim 3, wherein the outer ring surface of the arc-shaped strip away from the butt joint notch is formed with a long tooth, and the outer wall surface of the butt joint notch is symmetrically provided with a short tooth upward and downward; the outer ring surface of the arc-shaped connecting strip is formed with an arc-shaped protruding strip which cooperates with the butt joint notch, and the outer ring surface of the arc-shaped protruding strip is formed with a middle tooth; the distance between adjacent two short teeth, the middle tooth and the long tooth is the same, the length of the middle tooth is the same as the distance between the upward and downward two short teeth, and the shape of the middle tooth aligned with the upward and downward two short teeth is the same as that of the long tooth; the power assembly comprises a motor installed on the bending plate and a gear connected with the output shaft of the motor; wherein the gears are in meshing transmission with the short tooth, the middle tooth and the long tooth.

5. The rotation shaft calibration device of the dissolution tester according to claim 4, wherein the power assembly further comprises a T-shaped guide groove opened on the inner ring surface of the arc-shaped strip, a T-shaped sliding strip movably installed in the T-shaped guide groove, and a second screw connecting the T-shaped sliding strip and the vertical plate of the bending plate.

6. The rotation shaft calibration device of the dissolution tester according to claim 5, wherein The radial pushing assembly comprises a T-shaped linear strip arranged on the horizontal plate of the bending plate, a linear sliding strip movably sleeved on the T-shaped linear strip, and an L-shaped supporting plate arranged on the linear sliding strip and used for mounting the laser displacement sensor or the verticality calibration unit; The linear sliding strip is internally provided with a T-shaped cavity matched with the T-shaped linear strip, and the end of the T-shaped cavity facing the shaft rod is in an open state, and the other end is in a blocked state. The top wall of the T-shaped cavity is provided with an adjusting long groove for the third screw to move through; When the bending plate is mounted on the base body, the T-shaped linear strip faces the center line direction of the dissolution cup.

7. The shaft calibration device of the dissolution tester according to claim 6, wherein, The radial pushing assembly further comprises a spring member arranged on the horizontal plate of the L-shaped supporting plate, a supporting plate arranged on the top of the spring member, a first threaded hole arranged on the supporting plate and aligned with the spring member, and a second threaded hole arranged on the horizontal plate of the L-shaped supporting plate and aligned with the first threaded hole; When the verticality calibration unit is arranged on the supporting plate, it is connected with the first threaded hole through the fourth screw; When the laser displacement sensor is arranged on the supporting plate, it is connected with the second threaded hole through the fourth screw.

8. The shaft calibration device of the dissolution tester according to claim 7, wherein, The verticality calibration unit comprises a protective box arranged outside the inclination sensor, a threading hole arranged on the wall of the protective box, and a semicircular groove arranged on the vertical side wall of the protective box; The protective box and the laser displacement sensor are both provided with through holes for the fourth screw to pass through.

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