Special sterile medical precision filling machine for clean cabinet
By designing a sterile medical precision filling machine specifically for clean cabinets, the filling process of medicines is automatically controlled, solving the problems of inaccurate filling and low efficiency in existing technologies, and realizing efficient and sterile medicine filling.
Patent Information
- Application Number
- CN202512027684.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-12-30
- Publication Date
- 2026-02-13
AI Technical Summary
In existing technologies, the drug filling process relies on manual labor or simple machinery, which makes it difficult to guarantee the accuracy and uniformity of the filling volume. This can lead to the loss of efficacy or the risk of contamination of high-value drugs. In addition, the production efficiency is low, the operation is inconsistent, and the personnel training cost is high.
A sterile medical precision filling machine for clean cabinets was designed, which includes feeding, conveying, transmitting and collecting mechanisms. It automatically conveys bottles and stoppers, controls the filling volume through photoelectric sensors, achieves partial pressure on the stopper and filling of the liquid, and finally collects the liquid into the collection box, reducing manual operation.
It enables efficient and precise drug filling, improves production efficiency, reduces the risk of bottle contamination, and ensures filling consistency and aseptic condition.
Smart Images
Figure CN121516807A_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The application relates to the technical field of filling machines, in particular to a clean cabinet special sterile medical precision filling machine. BACKGROUND
[0002] In the field of sterile drug manufacturing, especially in the production of freeze-dried preparations (freeze-dried powder injections), high-activity biological preparations, vaccines, cell and gene therapy products and high-end medical and beauty products, the sterile guarantee level of the final product is the primary lifeline. Some drugs are initially in liquid form, then filled into bottles, then a plug is added but not tightly pressed, which is called a half-plug, then the bottle is placed in a freeze-drying cabinet (similar to a refrigerator), and after a period of freezing, the drug inside will become powder, then the plug is tightly pressed, and a lid is added to complete the delivery. Then, at the hospital or beauty salon, the lid is opened, and a certain drug is injected into the bottle, causing the freeze-dried powder to return to a liquid state, which is then injected into the human body or externally applied. Therefore, in drug manufacturing, filling is a key point in ensuring product quality. Currently, drugs are filled by relying on manual or simple mechanical filling.
[0003] However, relying on manual or simple mechanical filling, the accuracy and uniformity (precision and repeatability) of the filling volume are difficult to continuously guarantee. For high-value drugs, insufficient filling volume means a lack of therapeutic effect and compliance risk, and excessive filling volume can cause powder to overflow after freeze-drying, contaminating the bottle opening and affecting the sealing and sterile state. In the semi-automatic mode, filling and half-plug insertion operations may rely on manual operation or require multiple devices to be connected, which can cause inconsistent operation, low production efficiency, high personnel training costs and limitations due to personnel fatigue.
[0004] Therefore, a clean cabinet special sterile medical precision filling machine is proposed to solve the above problems. SUMMARY
[0005] The purpose of the present application is to provide a clean cabinet special sterile medical precision filling machine.
[0006] The clean cabinet special sterile medical precision filling machine provided by the present application adopts the following technical solution: A clean cabinet special sterile medical precision filling machine, comprising a filling machine, a bottle and a bottle plug, wherein the surface of the filling machine is provided with a feeding seat, a plurality of groups of bottles are slidably connected inside the feeding seat, the surface of the filling machine is provided with a lifting frame, one end of the lifting frame is fixedly connected with a plug pressing cross arm, the surface of the feeding seat is fixedly connected with a connecting frame, the surface of the filling machine is provided with a feeding mechanism for conveying bottles, the surface of the filling machine is provided with a conveying mechanism for conveying bottle plugs, the surface of the filling machine is provided with a conveying mechanism for moving bottles, and the inside of the conveying mechanism is provided with a collecting mechanism for collecting bottles.
[0007] Preferably, the surface of the connecting frame is fixedly connected with detection electric eyes, and the bottom of the filling machine is fixedly connected with multiple groups of supporting blocks.
[0008] Preferably, the feeding mechanism comprises a feeding frame, a rotating disc, a fixed block, a baffle and a blocking frame, the surface of the filling machine is provided with the feeding frame, the inside of the feeding frame is rotatably connected with the rotating disc, the inside of the feeding frame is fixedly connected with the fixed block, the surface of the fixed block is fixedly connected with the baffle, and the surface of the connecting frame is provided with the blocking frame.
[0009] Through the above technical scheme, multiple groups of bottles are placed in the feeding frame, the rotating disc is started to drive the bottles to rotate, and the movement track of the bottles is blocked by the baffle and the blocking frame, so that the bottles can be moved to the feeding seat.
[0010] Preferably, the conveying mechanism comprises a conveyor, a conveying groove, a pressing plate, a pressing plug rod and a clamping plate, the surface of the filling machine is provided with the conveyor, the surface of the conveyor is provided with the conveying groove, and the inner wall of the conveying groove is slidably connected with multiple groups of bottle plugs.
[0011] Preferably, the surface of the pressing plug cross arm is provided with the pressing plate, the inside of the pressing plug cross arm is slidably connected with the pressing plug rod, and the surface of the pressing plug cross arm is provided with the clamping plate.
[0012] Through the above technical scheme, the bottle plug is conveyed below the pressing plate, the pressing plate is started to move the bottle plug to the clamping plate, and then the pressing plug rod is started to press the bottle plug, so that the bottle plug is half-pressed to the bottle mouth of the bottle.
[0013] Preferably, the conveying mechanism comprises a fixed frame, a sliding groove, a first driving motor, a threaded rod, a sliding block, a fixed plate, an electric push rod, a connecting plate, a second driving motor, a rotating block and a blocking rod, one end surface of the filling machine is fixedly connected with two groups of fixed frames, the inner walls of the two groups of fixed frames are both provided with sliding grooves, the inside of the fixed frame is fixedly connected with the first driving motor, one end of the first driving motor is fixedly connected with the threaded rod, one end of the threaded rod is rotatably connected with the fixed frame, the surface of the threaded rod is threadedly connected with the sliding block, and the surface of the sliding block is fixedly connected with the fixed plate.
[0014] Through the above technical scheme, the first driving motor is started to drive the threaded rod to rotate, and the sliding block can move left and right in the sliding groove through the rotation of the threaded rod.
[0015] Preferably, one end of the fixed plate is internally provided with the electric push rod, one end of the electric push rod is fixedly connected with the connecting plate, the inside of the fixed plate is slidably connected with the connecting plate, one side of the fixed plate is internally fixedly connected with the second driving motor, one end of the second driving motor is fixedly connected with the rotating block, one end of the rotating block is rotatably connected with the fixed plate, and the surface of the rotating block is fixedly connected with the blocking rod.
[0016] Preferably, the collecting mechanism comprises spring grooves, springs, catches, collecting boxes, catch grooves and handles, spring grooves are arranged in the inner walls of one side of the two groups of fixing frames, springs are arranged in the inner walls of the spring grooves, and the one ends of the springs are fixedly connected with catches.
[0017] Preferably, collecting boxes are slidingly connected between the two groups of fixing frames, catch grooves are arranged in the surfaces of the collecting boxes, the catch grooves are matched with the springs, and handles are fixedly connected to one end of the collecting boxes.
[0018] Through the above technical scheme, the collecting box is inserted between the two groups of fixing frames, the surface of the collecting box can extrude the spring and the catch, and when the position of the collecting box is appropriate, the spring reset can push the catch to be inserted into the catch groove, so that the collecting box can be clamped between the two groups of fixing frames.
[0019] Preferably, the surface of the pressing plug cross arm is slidingly connected with a liquid outlet needle, the surface of the pressing plug cross arm is provided with a handle, the inside of the filling machine is provided with a guide rail, and the surface of the guide rail is slidingly connected with a connecting block.
[0020] Technical effects and advantages of the present application: Compared with the prior art, the sterile medical precision filling machine special for clean benches can automatically convey bottles and bottle plugs through the feeding mechanism and the conveying mechanism, detect the bottles through the detection electric eye, and detect the conveying speed of the bottles. When the bottle opening of the bottle passes through the liquid outlet needle, the liquid is sent into the bottle through the liquid outlet needle, so as to avoid insufficient filling amount. When the bottle body containing the liquid passes through the pressing plug rod, the pressing plate is started to move the bottle plug to the clamping plate, and then the pressing plug rod is started to press the bottle plug, so that the bottle plug is semi-pressed to the bottle opening of the bottle, and then the filling is completed. The conveying mechanism and the collecting mechanism are used to place the bottles on the collecting boxes in rows, so as to collect the filled bottles on the collecting boxes, and then the filled bottles are taken out uniformly. The filling process does not need manual operation, the filling efficiency of the bottles is greatly improved, and the possibility of bottle pollution is reduced. BRIEF DESCRIPTION OF DRAWINGS
[0021] Figure 1 It is a whole structure schematic view of the present application; Figure 2 It is a filling machine and feeding rack cooperation structure schematic view of the present application; Figure 3 It is a filling machine and feeding seat cooperation structure schematic view of the present application; Figure 4 It is a feeding seat and bottle cooperation structure schematic view of the present application; Figure 5 It is a conveying mechanism structure schematic view of the present application; Figure 6 It is a guide rail and connecting block cooperation structure schematic view of the present application; Figure 7 Figure 6 is a schematic view of the fixed plate and the electric push rod of the application; Figure 8 Figure 7 is a schematic view of the fixed frame and the blocking rod of the application; Figure 9 Figure 8 is a schematic view of the conveying mechanism of the application; Figure 10 Figure 9 is a schematic view of the rotating block and the blocking rod of the application; Figure 11 Figure 10 is a schematic view of the collecting mechanism of the application; Figure 12 Figure 11 is a schematic view of the Figure 11 Figure 12 is an enlarged view of A in Figure 11.
[0022] The reference signs are as follows: 1, filling machine; 2, feeding seat; 3, feeding mechanism; 301, feeding frame; 302, rotating disc; 303, fixed block; 304, blocking plate; 305, blocking frame; 4, lifting frame; 5, pressing plug cross arm; 6, conveying mechanism; 601, conveyor; 602, conveying groove; 603, pressing plate; 604, pressing plug rod; 605, clamping plate; 7, bottle; 8, conveying mechanism; 801, fixed frame; 802, sliding groove; 803, first driving motor; 804, threaded rod; 805, sliding block; 806, fixed plate; 807, electric push rod; 808, connecting plate; 809, second driving motor; 810, rotating block; 811, blocking rod; 9, collecting mechanism; 901, spring groove; 902, spring; 903, clamping pin; 904, collecting box; 905, clamping pin groove; 906, handle; 10, bottle plug; 11, connecting frame; 12, detection electric eye; 13, liquid outlet needle; 14, handle; 15, guide rail; 16, connecting block; 17, supporting block. DETAILED DESCRIPTION
[0023] The technical solutions in the embodiments of the application will be clearly and completely described below with reference to the drawings in the embodiments of the application. Obviously, the described embodiments are only part of the embodiments of the application, rather than all the embodiments of the application. Based on the embodiments in the application, all other embodiments obtained by those skilled in the art without creative work fall within the protection scope of the application. EMBODIMENT
[0024] As Figures 1 to 12The utility model provides a kind of sterile medical precision filling machine special for clean bench, including filling machine 1, bottle 7 and bottle plug 10, the surface of filling machine 1 is equipped with feed seat 2, the inside of feed seat 2 is slidably connected with multiple groups of bottle 7, so that bottle 7 can move in feed seat 2, the surface of filling machine 1 is equipped with lifting frame 4, one end of lifting frame 4 is fixedly connected with press plug cross arm 5, lifting frame 4 can drive press plug cross arm 5 to move up and down by being started, the surface of feed seat 2 is fixedly connected with connecting frame 11, the surface of filling machine 1 is equipped with feeding mechanism 3 for conveying bottle 7, for conveying bottle 7 into feed seat 2, the surface of filling machine 1 is equipped with conveying mechanism 6 for conveying bottle plug 10, for conveying bottle plug 10, so that bottle plug 10 can be covered on bottle 7, the surface of filling machine 1 is equipped with conveying mechanism 8 for moving bottle 7, for placing filled bottle 7 on collection box 904, the inside of conveying mechanism 8 is equipped with collection mechanism 9 for collecting bottle 7, so that filled bottle 7 is all collected on collection box 904, to be conveniently taken out uniformly.
[0025] As a preferred embodiment, the surface of connecting frame 11 is fixedly connected with detection electric eye 12, for detecting bottle 7 and the transmission speed of bottle 7, the bottom of filling machine 1 is fixedly connected with multiple groups of support blocks 17, for supporting filling machine 1, so that filling machine 1 does not shake when in use.
[0026] As a preferred embodiment, feeding mechanism 3 includes feeding rack 301, turntable 302, fixed block 303, baffle 304 and blocking frame 305, the surface of filling machine 1 is equipped with feeding rack 301, the inside of feeding rack 301 is rotatably connected with turntable 302, the inside of feeding rack 301 is fixedly connected with fixed block 303, the surface of fixed block 303 is fixedly connected with baffle 304, the surface of connecting frame 11 is equipped with blocking frame 305, multiple bottles 7 are placed in feeding rack 301, start turntable 302 to drive bottle 7 to rotate, the movement track of bottle 7 is blocked by baffle 304 and blocking frame 305, so that bottle 7 can move into feed seat 2.
[0027] As a preferred embodiment, conveying mechanism 6 includes conveyor 601, conveying groove 602, pressing plate 603, press plug rod 604 and clamping plate 605, the surface of filling machine 1 is equipped with conveyor 601, the surface of conveyor 601 is provided with conveying groove 602, the inner wall of conveying groove 602 is slidably connected with multiple bottle plugs 10, for conveying bottle plug 10.
[0028] As a preferred embodiment, the surface of press plug cross arm 5 is provided with pressing plate 603, the inside of press plug cross arm 5 is slidably connected with press plug rod 604, the surface of press plug cross arm 5 is provided with clamping plate 605, bottle plug 10 is conveyed to the lower side of pressing plate 603, start pressing plate 603 to move bottle plug 10 to clamping plate 605, and then start press plug rod 604 to press bottle plug 10, so that bottle plug 10 is half-pressed to the bottle mouth of bottle 7.
[0029] As a preferred implementation, the conveying mechanism 8 comprises a fixed frame 801, a sliding groove 802, a first drive motor 803, a threaded rod 804, a sliding block 805, a fixed plate 806, an electric push rod 807, a connecting plate 808, a second drive motor 809, a rotating block 810 and a stop rod 811, one end surface of the filling machine 1 is fixedly connected with two groups of fixed frames 801, the inner walls of the two groups of fixed frames 801 are each provided with a sliding groove 802, the inside of the fixed frame 801 is fixedly connected with a first drive motor 803, one end of the first drive motor 803 is fixedly connected with a threaded rod 804, one end of the threaded rod 804 is rotatably connected with the fixed frame 801, the surface of the threaded rod 804 is threadedly connected with a sliding block 805, the surface of the sliding block 805 is fixedly connected with a fixed plate 806, starting the first drive motor 803 can drive the threaded rod 804 to rotate, and the sliding block 805 can move left and right in the sliding groove 802 through the rotation of the threaded rod 804.
[0030] As a preferred implementation, one end of the fixed plate 806 is internally provided with an electric push rod 807, one end of the electric push rod 807 is fixedly connected with a connecting plate 808, the inside of the fixed plate 806 is slidably connected with the connecting plate 808, starting the electric push rod 807 can drive the connecting plate 808 to move left and right in the fixed plate 806, one side of the fixed plate 806 is internally fixedly connected with a second drive motor 809, one end of the second drive motor 809 is fixedly connected with a rotating block 810, one end of the rotating block 810 is rotatably connected with the fixed plate 806, the surface of the rotating block 810 is fixedly connected with a stop rod 811, starting the second drive motor 809 can drive the rotating block 810 to rotate, so that the stop rod 811 can be lifted.
[0031] As a preferred implementation, the collecting mechanism 9 comprises a spring groove 901, a spring 902, a bayonet 903, a collecting box 904, a bayonet groove 905 and a handle 906, the inner walls of one side of the two groups of fixed frames 801 are each provided with a spring groove 901, the inner walls of the spring groove 901 are provided with a spring 902, one end of the spring 902 is fixedly connected with a bayonet 903.
[0032] As a preferred implementation, the two groups of fixed frames 801 are slidably connected with a collecting box 904, the surface of the collecting box 904 is provided with a bayonet groove 905, the bayonet groove 905 cooperates with the spring 902, one end of the collecting box 904 is fixedly connected with a handle 906, the collecting box 904 is inserted between the two groups of fixed frames 801, the surface of the collecting box 904 will press the spring 902 and the bayonet 903, after the position of the collecting box 904 is appropriate, the spring 902 resets to push the bayonet 903 to be inserted in the bayonet groove 905, so that the collecting box 904 can be clamped between the two groups of fixed frames 801.
[0033] As a preferred embodiment, the surface of the plug cross arm 5 is slidably connected with the liquid outlet needle 13, the liquid can be sent into the bottle 7 through the liquid outlet needle 13, the surface of the plug cross arm 5 is provided with a handle 14, the height of the liquid outlet needle 13 can be adjusted, the inside of the filling machine 1 is provided with a guide rail 15, the surface of the guide rail 15 is slidably connected with a connecting block 16, the guide rail 15 drives the connecting block 16 to move left and right, so that the bottle 7 can move in the feeding seat 2.
[0034] The working process of the present application is as follows: a plurality of bottles 7 are placed in the feeding frame 301, the rotating disc 302 drives the bottles 7 to rotate, the movement track of the bottles 7 is blocked by the baffle 304 and the blocking frame 305, so that the bottles 7 can move into the feeding seat 2, the bottles 7 and the transmission speed are detected by the detection eye 12, when the bottle opening of the bottle 7 passes through the liquid outlet needle 13, the liquid is sent into the bottle 7 through the liquid outlet needle 13, when the bottle body containing liquid passes through the plug rod 604, the pressing plate 603 is started to move the bottle plug 10 to the clamping plate 605, and then the plug rod 604 is started to press the bottle plug 10, so that the bottle plug 10 is half-pressed to the bottle opening of the bottle 7, thereby completing the filling and conveying to the right side of the receiving end, the connecting plate 808 is driven by the electric push rod 807 to move, so that the bottles 7 move in order between the fixed plate 806 and the blocking rod 811, when the bottles 7 between the fixed plate 806 and the blocking rod 811 are collected, the first drive motor 803 drives the threaded rod 804 to rotate, the sliding block 805 moves in the sliding groove 802 through the rotation of the threaded rod 804, and then the fixed plate 806 is driven by the sliding block 805 to move, thereby moving the bottles 7 into the collecting box 904, when a row of bottles 7 are placed, the second drive motor 809 drives the rotating block 810 to rotate, so that the blocking rod 811 can be lifted, and then the fixed plate 806 is restored to the original position, so as to continue to move the subsequent bottles 7, and the above process is repeated, so that the bottles 7 can be placed row by row on the collecting box 904, thereby collecting the filled bottles 7 on the collecting box 904, so as to be taken out uniformly, the above is the working principle of the sterile cabinet special sterile medical precision filling machine.
Claims
1. A sterile medical precision filling machine for clean cabinets, comprising a filling machine (1), bottles (7) and bottle stoppers (10), wherein the surface of the filling machine (1) is provided with a feeding seat (2), and multiple sets of bottles (7) are slidably connected inside the feeding seat (2); the surface of the filling machine (1) is provided with a lifting frame (4), one end of the lifting frame (4) is fixedly connected with a stopper cross arm (5); and the surface of the feeding seat (2) is fixedly connected with a connecting frame (11), characterized in that: The surface of the filling machine (1) is provided with a feeding mechanism (3) for conveying bottles (7), the surface of the filling machine (1) is provided with a conveying mechanism (6) for conveying bottle plugs (10), the surface of the filling machine (1) is provided with a conveying mechanism (8) for moving bottles (7), and the inside of the conveying mechanism (8) is provided with a collecting mechanism (9) for collecting bottles (7).
2. A sterile medical precision filling machine for clean room according to claim 1, characterized in that: The surface of the connecting frame (11) is fixedly connected with a detection electric eye (12), and the bottom of the filling machine (1) is fixedly connected with a plurality of supporting blocks (17).
3. A sterile medical precision filling machine for clean room according to claim 1, wherein: The feeding mechanism (3) comprises a feeding frame (301), a rotating disc (302), a fixed block (303), a baffle (304) and a blocking frame (305), the surface of the filling machine (1) is provided with a feeding frame (301), the inside of the feeding frame (301) is rotatably connected with a rotating disc (302), the inside of the feeding frame (301) is fixedly connected with a fixed block (303), the surface of the fixed block (303) is fixedly connected with a baffle (304), and the surface of the connecting frame (11) is provided with a blocking frame (305).
4. A sterile medical precision filling machine for clean room according to claim 1, wherein: The conveying mechanism (6) comprises a conveyor (601), a conveying groove (602), a pressing plate (603), a plug pressing rod (604) and a clamping plate (605), the surface of the filling machine (1) is provided with a conveyor (601), the surface of the conveyor (601) is provided with a conveying groove (602), and the inner wall of the conveying groove (602) is slidably connected with a plurality of bottle plugs (10).
5. A sterile medical precision filling machine dedicated to clean room according to claim 4, characterized in that: The surface of the plug pressing cross arm (5) is provided with a pressing plate (603), the inside of the plug pressing cross arm (5) is slidably connected with a plug pressing rod (604), and the surface of the plug pressing cross arm (5) is provided with a clamping plate (605).
6. A sterile medical precision filling machine for clean room according to claim 1, wherein: The conveying mechanism (8) comprises a fixed frame (801), a sliding groove (802), a first driving motor (803), a threaded rod (804), a sliding block (805), a fixed plate (806), an electric push rod (807), a connecting plate (808), a second driving motor (809), a rotating block (810) and a blocking rod (811), one end surface of the filling machine (1) is fixedly connected with two groups of fixed frames (801), the inner walls of the two groups of fixed frames (801) are both provided with sliding grooves (802), the inside of the fixed frame (801) is fixedly connected with a first driving motor (803), one end of the first driving motor (803) is fixedly connected with a threaded rod (804), one end of the threaded rod (804) is rotatably connected with a fixed frame (801), the surface of the threaded rod (804) is threadedly connected with a sliding block (805), and the surface of the sliding block (805) is fixedly connected with a fixed plate (806).
7. A sterile medical precision filling machine dedicated to clean room according to claim 6, characterized in that: One end of the fixed plate (806) is internally provided with an electric push rod (807), one end of the electric push rod (807) is fixedly connected with a connecting plate (808), the inside of the fixed plate (806) is slidably connected with the connecting plate (808), one side of the fixed plate (806) is internally fixedly connected with a second driving motor (809), one end of the second driving motor (809) is fixedly connected with a rotating block (810), one end of the rotating block (810) is rotatably connected with the fixed plate (806), the surface of the rotating block (810) is fixedly connected with a blocking rod (811).
8. A sterile medical precision filling machine for clean room according to claim 1, wherein: The collecting mechanism (9) includes spring grooves (901), springs (902), catch pins (903), collecting boxes (904), catch pin grooves (905) and handles (906), the inner walls of the two groups of fixed frames (801) are both provided with spring grooves (901), the inner walls of the spring grooves (901) are provided with springs (902), one end of the spring (902) is fixedly connected with a catch pin (903).
9. A sterile medical precision filling machine dedicated to clean room according to claim 8, characterized in that: The collecting boxes (904) are slidably connected between the two groups of fixed frames (801), the surface of the collecting box (904) is provided with a catch pin groove (905), the catch pin groove (905) is matched with the spring (902), one end of the collecting box (904) is fixedly connected with a handle (906).
10. A sterile medical precision filling machine for clean room cabinet as claimed in claim 1, wherein: The surface of the pressing plug cross arm (5) is slidably connected with a liquid outlet needle (13), the surface of the pressing plug cross arm (5) is provided with a handle (14), the inside of the filling machine (1) is provided with a guide rail (15), the surface of the guide rail (15) is slidably connected with a connecting block (16).