Herbicide composition containing oxazole sulcotrione and application thereof

Abstract

The invention discloses a weeding composition containing oxazole sulcotrione and application of the weeding composition, and relates to the field of pesticides, the effective components of the weeding composition comprise a herbicide A and a herbicide B. The herbicide A is the oxazole sulcotrione, and the herbicide B is an ALS inhibitor; the weight ratio of the herbicide A to the herbicide B is (1-80): (80-1); the ALS inhibitor is selected from one or more of penoxsulam, pyribenzoxim, bispyribac-sodium, pyriminobac-methyl, bensulfuron methyl, pyrazosulfuron methyl, halosulfuron-methyl, metazosulfuron methyl, triafamone, flucetosulfuron and propyrisulfuron methyl. According to the composition disclosed by the invention, the oxazole sulcotrione is compounded with two medicaments with different mechanisms, so that the composition has an obvious gain effect on preventing and removing weeds such as barnyard grass and the like in a paddy field, and the usage amount of active ingredients can be reduced.

Description

Technical Field

[0001] This invention relates to the field of pesticide technology, and in particular to a herbicide composition containing oxazolidinone and its application. Background Technology

[0002] The information contained in this background section is intended only to enhance understanding of the overall background of the invention and should not be construed as an admission or in any way implying that such information constitutes prior art known to those skilled in the art.

[0003] Chemical weeding is the most economical and effective means of controlling weeds in farmland. However, because rice paddies are usually infested with a variety of weeds and the resistance of rice paddy weeds is increasing, the difficulty of control is increasing. A single active ingredient cannot control rice paddy weeds in one go.

[0004] The rational combination or mixing of herbicides can enhance efficacy, delay resistance, and broaden the spectrum of weed control, making it an important means of solving weed problems. Therefore, there is an urgent need in agricultural production for effective herbicide compositions for controlling weeds in rice paddies.

[0005] The active ingredient, oxazolidinone, is an innovative HPPD-type highly selective systemic herbicide for rice paddies, developed by Shandong Binong Technology Co., Ltd. It is highly safe for rice and is primarily absorbed through the plant's roots and stems, causing the new leaves of weeds to turn white. It is effective against annual weeds such as barnyard grass, Echinochloa crus-galli, Cyperus difformis, and Eclipta prostrata. We use oxazolidinone in combination with herbicides of different mechanisms of action to control all annual weeds in a single application in rice paddies, reducing labor costs for farmers and solving rice paddy weed problems in the simplest way. Summary of the Invention

[0006] Purpose of the invention

[0007] To overcome the above-mentioned shortcomings, the present invention aims to provide a herbicide composition containing oxazolidinone and its application. The composition of the present invention can effectively control weeds such as barnyard grass, barnyard grass, crabgrass, duckweed, angelica, water celery, knotweed, sedge, sedge, and floating grass in crop fields. It has the characteristics of broadening the weed control spectrum, improving the control effect, eliminating weed damage and reducing the likelihood of resistance, reducing the amount of pesticide used, saving costs, and reducing environmental pressure.

[0008] Solution

[0009] To achieve the objectives of this invention, the technical solution adopted is as follows:

[0010] In a first aspect, the present invention provides a herbicide composition comprising oxazolidinone, wherein the active ingredients include herbicide A and herbicide B, wherein herbicide A is oxazolidinone and herbicide B is an ALS inhibitor; the weight ratio of herbicide A to B is 1-80:80-1.

[0011] The chemical structural formula of oxazolidinone is as follows:

[0012]

[0013] Further, the weight ratio of herbicides A and B is 1–60:60–1, optionally 1–50:50–1, optionally 1–40:40–1, optionally 1–30:30–1, optionally 1:20–20:1, optionally 1:15–15:1, optionally...

[0014] (15:1)~(5:6), optionally (15:2)~(5:6), optionally (15:2)~(5:5), optionally (15:1)~(5:5), optionally (10:1)~(5:5), optionally (5:1)~(5:5), optionally (15:1)~(5:1), optionally (10:1)~(10:3),

[0015] The possible ratios are 15:1, 10:1, 15:2, 5:1, 10:3, 3:1, 5:2, 5:3, 5:4, 5:5, and 5:6.

[0016] Furthermore, the ALS inhibitor is selected from one or more of penoxsulam, pyrimisulfuron, bispyribac-sodium, pyrimisulfuron, bensulfuron-methyl, pyrimisulfuron, chlorpyrifos, pyrimisulfuron-methyl, fluoxetine, flupyrsulfuron, and promethazine; when herbicide B includes penoxsulam, the weight ratio of oxazetine to penoxsulam is (5:1) to (1:1), and optionally the weight ratio is 5:1, 3:1, 5:3 or 1:1;

[0017] When herbicide B includes flumetsulam, the weight ratio of oxazolidinone to flumetsulam is (5:1) to (1:1).

[0018] The optional weight ratios are 5:1, 3:1, 5:3, or 1:1;

[0019] When herbicide B includes pyrimisulfuron, the weight ratio of oxazolidinone to pyrimisulfuron is (15:1) to (5:1).

[0020] The optional weight ratio is 15:1 or 5:1;

[0021] When herbicide B includes bensulfuron-methyl, the weight ratio of oxazolidinone to bensulfuron-methyl is (15:2) to (5:6).

[0022] The optional weight ratios are 15:2, 5:2, 5:4, or 5:6;

[0023] When herbicide B includes bispyribac-sodium, the weight ratio of oxazolidinone to bispyribac-sodium is (15:1) to (5:5), and optionally the weight ratio is 15:1, 5:1, 3:1, 5:3 or 1:1.

[0024] When herbicide B includes pyrimiflunomide, the weight ratio of oxazolidinone to pyrimiflunomide is (10:1) to (10:1).

[0025] 3) The optional weight ratio is 10:1, 10:2 or 10:3;

[0026] When herbicide B includes chlorpyrifos, the weight ratio of oxazolidinone to chlorpyrifos is (15:2) to (5:1).

[0027] 6) The weight ratio can be optionally 5:2, 5:1 or 15:2.

[0028] Furthermore, when herbicide B is penoxsulam or fluoxetine, the weight ratio of herbicide A to herbicide B is (5-15):(1-5), and optionally the weight ratio is 5:1, 3:1, 5:3 or 1:1;

[0029] Alternatively, when herbicide B is pyrimisulfuron, the weight ratio of herbicide A to herbicide B is (15:1) to (5:1), and optionally the weight ratio is 15:1 or 5:1.

[0030] Alternatively, when herbicide B is bensulfuron-methyl or bispyribac-sodium, the weight ratio of herbicides A and B is (15:1) to (5:1).

[0031] 6), optionally (15:2) to (5:5), optionally with a weight ratio of 15:1, 15:2, 5:1, 3:1, 5:3, 5:2, 5:4, 5:5 or 5:6;

[0032] Alternatively, when herbicide B is pyrimifluazuron, the weight ratio of herbicides A and B is (10:1) to (10:3), optionally 10:1, 10:2, or 10:3.

[0033] Alternatively, when herbicide B is chlorpyrifos, the weight ratio of herbicide A to herbicide B is (15:2) to (5:2), and optionally the weight ratio is 5:2, 5:1 or 15:2.

[0034] Further, the active ingredient accounts for 1-95 wt% of the total weight of the composition, optionally 5%-80 wt%, optionally 6%-45 wt%.

[0035] Furthermore, the herbicide composition is in the form of a dispersible oil suspension, an aqueous suspension, a suspension emulsion, a wettable powder, an emulsifiable concentrate, a water-dispersible granule, an emulsion, or a microemulsion.

[0036] Furthermore, the herbicidal composition further includes adjuvants selected from one or more of the following: safeners, dispersants, wetting agents, emulsifiers, solvents, cosolvents, antifreeze agents, stabilizers, preservatives, thickeners, binders, defoamers, acid-adjusting media, alkali-adjusting media, and solid inert carriers.

[0037] Furthermore, the safener is selected from one or more of the following: bis(oxazolyl) acid, cyprosulfamide, pyrazolyl glufosinate, quinoline, gibberellic acid, furilazole, and metcamifen;

[0038] And / or, the dispersant comprises one or more of the following: sodium lignosulfonate, calcium lignosulfonate, sodium polyacrylate, methylene bis(naphthalene) sulfonate, calcium alkylbenzene sulfonate, amine alkylbenzene sulfonate, sodium methylene bis(naphthalene) sulfonate formaldehyde condensate, polyoxyethylene-polyoxypropylene block copolymer, carboxymethyl cellulose, polyvinyl alcohol, polyvinylpyrrolidone, polycarboxylate, alkylnaphthalene sulfonate condensate, etc.

[0039] And / or, the wetting agent includes one or more of the following: pull-apart powder, sodium dodecyl sulfate, condensate of fatty alcohol and ethylene oxide, fast T, naphthalene sulfonate formaldehyde condensate, alkyl naphthalene sulfonate, aryl polyoxyethylene ether phosphate, alkyl sulfate, sodium alkyl aryl sulfonate, alkylphenol polyoxyethylene ether phosphate, fatty alcohol polyoxyethylene ether, sorbitan fatty acid ester polyoxyethylene ether, azone, and organosilicon wetting agents;

[0040] And / or, the emulsifier includes one or more of the following: agricultural emulsion 400#, agricultural emulsion 500#, agricultural emulsion 600#, agricultural emulsion 700#, NP series, 0201B, 0203B, 2201, Ningru No. 31, Ningru No. 33, Ningru No. 37, 0202, 0202C, block polyether, alkylphenol polyoxyethylene ether sulfosuccinate, castor oil polyoxyethylene ether, fatty acid polyoxyethylene ether, polyoxyethylene fatty alcohol ether, ethoxylated castor oil, polymethyl acrylate, fatty acid polyethylene glycol ester, glyceryl trilaurate polyoxyethylene ether, etc.

[0041] And / or, the solvent includes one or more of the following: acetone, butanone, cyclohexanone, toluene, xylene, trimethylbenzene, tetramethylbenzene, methylnaphthalene, methyl oleate, ethyl acetate, fatty acid methyl ester, pine oil, soybean oil, rapeseed oil, biodiesel, ethanol, n-propanol, isopropanol, propylene glycol, glycerol, n-butanol, isooctyl alcohol, sec-butyl acetate, dimethyl carbonate, diesel oil, white oil, engine oil, dibasic ester, N-methylpyrrolidone, N,N-dimethylformamide, isophorone, deionized water, etc.

[0042] And / or, the cosolvent includes one or more of ethanol, n-propanol, isopropanol, propylene glycol, glycerol, n-butanol, isooctyl alcohol, etc.

[0043] And / or, the antifreeze includes one or more of sorbitol, ethylene glycol, polyethylene glycol, propylene glycol, glycerol, urea, and sodium chloride;

[0044] And / or, the stabilizer includes one or more of sodium citrate, resorcinol, epoxidized soybean oil, epichlorohydrin, epoxidized linseed oil, pentaerythritol, xylitol, butylated hydroxyanisole, etc.

[0045] And / or, the preservative includes one or more of formaldehyde, benzoic acid, sodium benzoate, potassium sorbate, Kathon, isothiazolinone, etc.

[0046] And / or, the thickener includes one or more of xanthan gum, gelatin, gum arabic, polyvinyl alcohol, bentonite, magnesium aluminum silicate, carboxymethyl cellulose, carboxyethyl cellulose, methyl cellulose, etc.

[0047] And / or, the binder includes one or more of the following: glucose, sucrose, hydroxyethyl cellulose, soluble starch, polyethylene glycol, methyl cellulose, polycarboxylic acids and water-soluble polymers such as sodium carboxymethyl cellulose, polyvinyl alcohol, paraffin wax, gypsum, hydroxypropyl methyl cellulose, and polyacrylamide.

[0048] And / or, the defoamer includes one or more of C8-10 fatty alcohol compounds, epoxidized soybean oil, ethanol, silicone compounds, organosilicon oil, and C10-20 saturated fatty acid compounds;

[0049] And / or, the acid-adjusting medium includes one or more of the following: organic acids such as benzoic acid, citric acid, acetic acid, acetic anhydride, propionic acid, and methanesulfonic acid; and inorganic acids such as hydrochloric acid, sulfuric acid, and phosphoric acid.

[0050] And / or, the alkali-adjusting medium includes one or more of the following: organic bases such as ethylenediamine, triethylamine, triethanolamine, triisopropanolamine, ammonia, and urea; and inorganic bases or salts such as sodium carbonate, sodium bicarbonate, and sodium hydroxide.

[0051] And / or, the solid inert carrier includes one or more of the following: light calcium carbonate, diatomaceous earth, bentonite, attapulgite, silica, kaolin, and corn starch.

[0052] Furthermore, it is used to control one or more of the following: barnyard grass, angelica, Echinochloa crus-galli, sedge, water hyacinth, sedge, crabgrass, duckweed, water amaranth, clove knotweed, sedge, and floating grass; optionally, it is used to control harmful weeds in paddy fields.

[0053] In a second aspect, the application of the herbicide composition described in the first aspect in the control of harmful weeds in crop fields is provided.

[0054] Furthermore, the harmful weeds are one or more of the following: barnyard grass, angelica sinensis, Echinochloa crus-galli, sedge, water hyacinth, sedge, crabgrass, duckweed, water amaranth, clove knotweed, sedge, and floating grass; optionally, they are used for the control of harmful weeds in paddy fields.

[0055] The compositions of the present invention can be prepared into the desired dosage form using conventional dosage form methods.

[0056] Beneficial effects

[0057] (1) The composition of the present invention combines oxazolidinone with two agents with different mechanisms of action, resulting in a significant synergistic effect in controlling barnyard grass in paddy fields. This reduces the amount of active ingredient used and lowers the risk of resistance to herbicides with a single mechanism of action.

[0058] (2) The composition of the present invention can be applied to the leaves or buds of the plant to be treated by spraying or applying soil, i.e., to weeds, especially weeds that are harmful to crop growth or to the soil surface on which they grow.

[0059] (3) The herbicide composition of the present invention is suitable for controlling weeds in paddy fields, including but not limited to barnyard grass, Echinochloa crus-galli, Eclipta prostrata, Amaranth, Cyperus rotundus, etc.

[0060] (4) By rationally matching the content of the components, this invention not only has good weed control effect and low cost, but also its activity and weed control effect are not a simple superposition of the activities of each component. Within the reasonable ratio range, it has a significant additive effect, good safety to crops, and meets the safety requirements of herbicide formulations.

[0061] (5) The herbicide composition of the present invention is also environmentally friendly and easily degraded in the environment.

[0062] (6) The herbicide composition of the present invention is convenient to use, saves costs, and has great economic and social benefits. Detailed Implementation

[0063] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0064] Furthermore, to better illustrate the present invention, numerous specific details are provided in the following detailed embodiments. Those skilled in the art should understand that the present invention can be practiced without certain specific details. In some embodiments, materials, methods, means, etc., well-known to those skilled in the art, are not described in detail in order to highlight the spirit of the present invention.

[0065] Unless otherwise expressly stated, throughout the specification and claims, the term "comprising" or its variations such as "including" or "comprises" shall be understood to include the stated elements or components without excluding other elements or other components.

[0066] The above-described herbicide compositions provide a new option for controlling plant diseases. The following examples further illustrate this disclosure, but this disclosure is not intended to be limiting.

[0067] Oazosulfone is an HPPD-type highly selective systemic herbicide for rice paddies, innovatively developed by Shandong Binnong Technology Co., Ltd. (The preparation method of oxazosulfone is referenced in Chinese patent application CN117247363A, which involves raw materials including 3-bromomethyl-2-chloro-4-methanesulfonylbenzoic acid, 5-methyl-1,3,4-oxadiazol-2(3H)-one, and 5-cyclopropyl-2-methyl-1,2-dihydro-3H-pyrazole-3-one (CAS: 199125-21-8)). 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carboxylic acid (also available to the public from Shandong Binong Technology Co., Ltd.), its chemical name is 5-chloro-1,3-dimethyl-1H-pyrazole-4-carboxylic acid-[4-{2-chloro-3-[(5-methyl-2-oxo-1,3,4-oxadiazol-3(2H)yl)methyl]-4-(methanesulfonyl)benzoyl}-3-cyclopropyl-1-methyl-1H-pyrazole-5-yl] ester, which is a white crystalline solid with a melting point of 212℃. Its chemical structure is as follows:

[0068]

[0069] In the following examples, penoxsulam, fluoxetine, pyrimisulfuron, bensulfuron, bispyribac-sodium, pyrimisulfuron-methyl, and clopyrimisulfuron are all commercially available, and the other adjuvants are also commercially available products.

[0070] The present invention will be further described in detail below through examples.

[0071] Test Example 1: Indoor Toxicity Determination

[0072] The indoor toxicity test method refers to the Gowing method in "Guidelines for Indoor Bioassay Tests of Pesticides - Herbicides Part 7: Determination of Combined Effects of Mixtures NY / T 1155.7-2006".

[0073] Experimental method: The pre-prepared oxazolidinone was dissolved with the technical grade of other single herbicides (pentoxuron, fluoxetine, pyrimisulfuron, bensulfuron, bispyribac-sodium, pyrimisulfuron-methyl, chlorpyrifos, chlorpyrifos-sodium, chlorpyrifos-sodium) and combination formulations.

[0074] Taking the mixture of agents A and B as an example, the actual control effect after mixing according to the above ratio is calculated according to formula (1):

[0075] E0 = X + Y (X * Y / 100)

[0076] In the formula:

[0077] X — Weed control efficacy of herbicide A at a dosage of P;

[0078] Y—Weed control efficacy of herbicide B at a dosage of Q;

[0079] E0——Theoretical efficacy of herbicide A at dosage P + theoretical efficacy of herbicide B at dosage Q;

[0080] E—The actual control effect of herbicide A and herbicide B when mixed in the above proportions.

[0081] E-E0 > 10% indicates a synergistic effect, E-E0 < -10% indicates an antagonistic effect, and E-E0 values ​​between ±10% indicate an additive effect.

[0082] When two active ingredients are combined to enhance or add to each other's effects, the combination is reasonable and has significant implications.

[0083] Test details:

[0084] 1) Experimental subjects: Grass weeds such as barnyard grass and broadleaf weeds such as sedge were collected from rice fields in Anhui Province and stored in a seed bank for future use.

[0085] 2) Cultivation conditions: Cultivation was conducted in the intelligent biological testing greenhouse of Shandong Binnong Technology Co., Ltd., with a temperature of 20-35℃, natural light, and relative humidity of 42%-87%. Pot cultivation was used. Small plastic nutrient pots and plastic flower pots were placed inside square plastic pots filled with topsoil collected from farmland, dried and sieved, mixed with sphagnum moss (soil:sphagnum moss = 3:1) at a ratio of 1.0%-1.4% organic matter content and a pH of approximately 7.0, filling the pots to 4 / 5 full. Initially, soil moisture was controlled at 20%, first moistening the soil to saturation. Then, plump and uniform weed seeds were selected and evenly distributed on the soil surface, covered with soil, and placed in a controlled-sunlight greenhouse for cultivation until use.

[0086] 3) Test reagents: The required active ingredients, oxazolidinone and penoxsulam, are produced by our company. Other active ingredients and reagents are purchased. The raw materials are all diluted with acetone as solvent and diluted to volume with a 0.1% T-80 emulsifier aqueous solution. Dilute immediately before use.

[0087] 4) Application method: Spray evenly on stems and leaves when weeds are at the 2-4 leaf stage.

[0088] 5) Application equipment: ASS-4 type mobile spray tower

[0089] 6) Investigation methods: Visually observe changes in the growth of weed stems and leaves, emergence rate, etc., compare the changes in growth and emergence rate with the blank control treatment, visually observe the poisoning symptoms of target weeds between treatments and record them in detail.

[0090] Absolute value survey method: During the last survey, the number of weeds and their fresh weight are investigated. The surviving weeds are cut off along the soil surface with scissors, and the fresh weight of the weeds is weighed with a balance. The plant control efficacy and fresh weight control efficacy of the tested agent against the weeds are calculated.

[0091] 7) Data Analysis: The theoretical fresh weight control efficacy (E0 = X + Y) for each treatment combination was calculated using the Gowing method. This was then compared with the actual fresh weight control efficacy (E) to evaluate the combined effect of the two treatments on weeds. When E - E0 > 10%, it was considered a synergistic effect; E - E0 < -10%, an antagonistic effect; and E - E0 between ±10%, an additive effect. The optimal ratio was determined based on actual control efficacy, weeding characteristics, and the balance of the formulation. In the formula, X represents the fresh weight control efficacy when the dosage of active ingredient A is P; and Y represents the fresh weight control efficacy when the dosage of active ingredient B is Q. When the combined effect of the two active ingredients is synergistic or additive, the combination is reasonable and has high significance.

[0092] The herbicide A (oxazolidinone) and herbicide B (pentoxuron, fluoxetine, pyrimisulfuron, bensulfuron, bispyribac-sodium, pyrimisulfuron, chlorpyrifos, chlorpyrifos-sodium, chlorpyrifos-sodium) were used.

[0093] The statistical results are shown in Table 1-7 below:

[0094] Table 1A contains oxazolidinone and B contains penoxsulam, with barnyardgrass as the target.

[0095] Table 1. Combined effects of oxazolidinone and penoxsulam on barnyardgrass

[0096]

[0097] The results in Table 1 show that the combined effects of oxazolidinone and penoxsulam on barnyardgrass in the range of (25:1) to (5:5) are additive or synergistic, with significant synergistic effects in the range of (5:1) to (1:1), especially at 5:1, 3:1, 5:3, and 1:1.

[0098] Table 2. Combined effects of oxazolidinone and fluazinam on barnyardgrass

[0099]

[0100] The results in Table 2 show that the combined effects of oxazolidinone and fluazinam on barnyardgrass in the range of (25:1) to (5:5) are additive or synergistic, with significant synergistic effects in the range of (5:1) to (1:1), especially at 5:1, 3:1, 5:3, and 1:1.

[0101] Table 3. Combined effects of oxazolidinone and pyrimisulfuron on snake intestines

[0102]

[0103]

[0104] The results in Table 3 show that the combined effects of oxazolidinone and pyrimisulfuron on snake intestines in the range of (25:1) to (5:5) are additive or synergistic, with significant synergistic effects in the range of (15:1) to (5:1), especially at 15:1 and 5:1.

[0105] Table 4. Combined effects of oxazolidinone and bensulfuron-methyl on snake intestines

[0106] The results in Table 4 show that the combined effects of oxazolidinone and bensulfuron-methyl on snake intestines in the range of (25:2) to (5:6) are additive or synergistic, with significant synergistic effects in the range of (15:2) to (5:6), especially at 15:2, 5:2, 5:4, and 5:6.

[0107] Table 5. Combined effects of oxazolidinone and bispyribac-sodium on barnyardgrass

[0108]

[0109]

[0110] Table 5 shows that the combined effects of oxazolidinone and bispyribac-sodium on barnyardgrass in the ratios of (25:1) to (5:5) were additive or synergistic, with a significant synergistic effect in the ratios of (15:1) to (5:5), especially at ratios of 15:1 and 5:1.

[0111] The synergistic effects of ratios 1, 3:1, 5:3, and 1:1 are significant.

[0112] Table 6. Combined effects of oxazolidinone and pyrimisulfuron on barnyardgrass

[0113] The results in Table 6 show that the combined effects of oxazolidinone and pyrimisulfuron on barnyardgrass in the range of (50:3) to (10:9) are additive or synergistic, with significant synergistic effects in the range of (10:1) to (10:3), especially at 10:1, 10:2, and 10:3.

[0114] Table 7. Combined effects of oxazolidinone and chlorpyrifos on snake intestines

[0115]

[0116]

[0117] The results in Table 7 show that the combined effects of oxazolidinone and chlorpyrifos on snake intestines at ratios of (15:2) to (5:6) are additive, with significant synergistic effects at (15:2) to (5:2), especially at (5:2), (5:1), and (15:2).

[0118] Therefore, it can be seen that herbicide A (oxazolidinone) and herbicide B (ALS inhibitors including penoxsulam, fluoxetine, pyrimisulfuron, bensulfuron, bispyribac-sodium, pyrimisulfuron, and chlorpyrifos) have a synergistic effect at a weight ratio of (15:1) to (5:6), especially at 15:1, 10:1, 15:2, 5:1, 10:3, 3:1, 5:2, 5:3, 5:4, 5:5, and 5:6.

[0119] Results of indoor formulation screening test: The binary mixture of oxazolidinone and ALS inhibitors (including penoxsulam, pyrimisulfuron, etc.) significantly improved the weed control efficacy, showing an additive or synergistic effect, and has high significance for mixing.

[0120] The formulation examples are as follows. All contents in the following examples are weight percentages.

[0121] Formulation Example 1: 8% Oxazosulfuron·Pivoxil OD (6:2)

[0122] The ingredients include the following: 6% oxazolidinone, 2% penoxsulam, 5% agricultural emulsifiable concentrate 500#, 3% agricultural emulsifiable concentrate 600#, 6% castor oil polyoxyethylene ether, 1% alkylphenol polyoxyethylene ether phosphoric acid, 1% bentonite, 1% silica, and methyl oleate to 100%.

[0123] Formulation Example 2: 8% Oxazosulfuron·Fluorazon OD (6:2)

[0124] The ingredients include the following: 6% oxazolidinone, 2% fluazinam, 5% agricultural emulsifiable concentrate 500#, 3% agricultural emulsifiable concentrate 600#, 6% castor oil polyoxyethylene ether, 1% alkylphenol polyoxyethylene ether phosphoric acid, 1% bentonite, 1% silica, and methyl oleate to 100%.

[0125] Formulation Example 3: 6% Oxasulfuron·Pyrimisulfuron SE (5:1)

[0126] 5% oxazolidinone, 1% pyrimisulfuron, 2% agricultural emulsifiable concentrate 500#, 1% agricultural emulsifiable concentrate 600#, 2% castor oil polyoxyethylene ether, 2.5% polycarboxylate, 1% alkyl naphthalene sulfonate condensate, 5% ethylene glycol, 0.1% xanthan gum, 0.3% Kathon, 0.3% silicone oil, 20% isophorone, water to 100%.

[0127] Formulation Example 4: 28% Oxazosulfuron·Benzylsulfuron WP (20:8)

[0128] The raw materials include: 6% oxazolidinone, 2% fluazinam, 3% sodium lignosulfonate, 1% polyoxyethylene-polyoxypropylene block copolymer, 2% sodium dodecyl sulfate, 10% silica, and kaolin to 100%.

[0129] Formulation Example 5: 8% Oxazosylsulfuron·Bissodium OD (6:2)

[0130] The ingredients include the following: 6% oxazolidinone, 2% bispyribac-sodium, 5% agricultural emulsifiable concentrate 500#, 4% agricultural emulsifiable concentrate 600#, 5% castor oil polyoxyethylene ether, 1% alkylphenol polyoxyethylene ether phosphoric acid, 1% bentonite, 1% silica, and methyl oleate to 100%.

[0131] Formulation Example 6: 26% Oxazosulfuron·Pyrimidine oxime-methyl EW (20:6)

[0132] The ingredients include: 20% oxazolidinone, 6% pyrimimethoxam, 20% solvent oil 150#, 1% agricultural emulsion 600#, 2% castor oil polyoxyethylene ether, 5% ethylene glycol, and water to make up the difference.

[0133] Formulation Example 7: 45% Oxazosulfuron·Clopyram WDG (35:15)

[0134] The ingredients include: 35% oxazolidinone, 15% chlorpyrifos, 3% sodium lignosulfonate, 1% polycarboxylate, 3% sodium dodecyl sulfate, 2% ammonium sulfate, 5% bentonite, and kaolin to make up to 100%.

[0135] Comparative Example 1: 6% Oxazolidinone OD

[0136] Formula: Includes the following raw materials: 6% oxazolidinone, 5% agricultural emulsion 500#, 2% agricultural emulsion 600#, 6% castor oil polyoxyethylene ether, 2% alkylphenol polyoxyethylene ether phosphoric acid, 1% bentonite, 1% silica, and methyl oleate to 100%.

[0137] Comparative Example 2: 2% Oxazosulfan Suspension

[0138] Formula: Oxalide 2%, polycarboxylate 2.5%, alkyl naphthalene sulfonate condensate 1%, aryl polyoxyethylene ether phosphate 1.0%, ethylene glycol 5%, xanthan gum 0.5%, magnesium aluminum silicate 1.2%, Kathon 0.3%, silicone oil 0.3%, water to 100%.

[0139] Comparative Example 3: 20% penoxsulam OD

[0140] The product is manufactured using finished products from Shandong Binnong Technology Co., Ltd. and is currently on sale.

[0141] Comparative Example 4: 10% Pyrimisulfuron WP

[0142] The product is manufactured using finished products from Shandong Binnong Technology Co., Ltd. and is currently on sale.

[0143] Comparative Example 5: 10% Pyrimioxime SC

[0144] Purchase finished formulations from Anhui Provincial Chemical Research Institute; they are currently for sale.

[0145] Comparative Example 6: 28% chlorpyrifos·triazolesulfonate OD

[0146] Purchase Qingyuan Nongguan's finished formulations, which are available for sale.

[0147] Field trials were conducted on the formulations of the above examples and comparative examples.

[0148] Field efficacy trial: Field efficacy trial of oxazolidinone combination formulation against weeds in paddy fields

[0149] Experimental crop: Direct-seeded rice field

[0150] Experimental subjects: barnyard grass, Echinochloa crus-galli, Cyperus rotundus, Alpinia oxyphylla, Eclipta prostrata, etc.

[0151] Experimental Methods: The experiment was conducted in Wuwei, Anhui Province. The rice variety used was Quanliangyou 851. A total of 14 treatments were included, with 3 replicates per treatment, for a total of 42 plots. Each plot was 50 m². 2 The study employed a randomized block design. Foliar spraying was conducted on rice plants at the 3-4 leaf stage, using 30L of water per mu (approximately 0.067 hectares). Drainage was applied during spraying to ensure that more than two-thirds of the weed stems and leaves were above the water surface. Water was returned to the surface two days after application, maintaining a water layer of 3-5 cm for 5-7 days. Weed fresh weight control efficacy was assessed 14 days post-application. Results are shown in Table 8.

[0152] Fresh weight control efficacy % = [(fresh weight of control weeds - fresh weight of treatment weeds) / fresh weight of control weeds] × 100.

[0153] Results: The field test results of the oxazolidinone compound formulation against weeds in paddy fields are shown in Table 8. At an effective dose of 7.2-12 g / mu, the compound formulation showed an inhibition rate of over 90% on the total fresh weight of weeds in paddy fields. Field observations at an effective dose of 12 g / mu showed the compound formulation to be safe for rice.

[0154] Table 8. Field efficacy trials of oxazolidinone combination formulations against weeds in rice paddies

[0155] Serial Number Treatment agents Effective dose per mu (g) Total protective efficacy % Formulation Example 1 8% Oxazolidinone·Pyfluzoxystrobin OD 8 96.32％ Formulation Example 2 8% Oxazolidinone·Fluoronesulfuron OD 8 92.15％ Formulation Example 3 6% Oxazosulfuron·Pyrimisulfuron SE 7.2 90.63％ Formulation Example 4 28% Oxazosulfuron·Benzylsulfuron WP 8 91.08％ Formulation Example 5 8% Oxazolidinone·Bismuth subtilis OD 8 92.33％ Formulation Example 6 26% Oxazosulfan·Pyrimisulfan EW 8 93.24％ Formulation Example 7 45% Oxazosulfuron·Clopyram WDG 8 92.87％ Comparative Example 1 6% Oxazolidinone OD 10 85.77％ Comparative Example 2 2% Oxazosulfan SC 10 73.51％ Comparative Example 3 20% penoxsulam OD 2.5 71.82％ Comparative Example 4 10% pyrimisulfuron WP 2 63.35％ Comparative Example 5 10% pyrimimethoxam SC 2.5 69.44％ Comparative Example 6 28% Diphthyl Acetate·Triazole Sulfonate OD 60 90.52％ - Blank control - -

[0156] Based on observations throughout the field trial, the rice grew well within the experimental dosage range, and no phytotoxicity was observed in any of the treatments, indicating that they are safe for rice.

[0157] The efficacy comparisons of various examples and comparative examples show that the mixture of herbicide A (oxazolidinone) and herbicide B (pentoxuron, fluoxazolidinone, pyrimisulfuron, bensulfuron, bispyribac-sodium, pyrimisulfuron, chlorpyrifos, chlorpyrifos-sodium, chlorpyrifos-sodium) can reduce the amount of herbicide applied and improve the control effect.

[0158] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A herbicide composition comprising oxazolidinone, characterized in that, Its active ingredients include herbicide A and herbicide B, where herbicide A is oxazolidinone and herbicide B is an ALS inhibitor; the weight ratio of herbicide A to herbicide B is 1-80:80-1. The chemical structural formula of oxazolidinone is as follows:

2. The herbicide composition according to claim 1, characterized in that, The weight ratio of herbicides A and B is 1-60:60-1, optionally 1-50:50-1, optionally 1-40:40-1, optionally 1-30:30-1, optionally 1:20-20:1, optionally 1:15-15:1, optionally (15:1)-(5:6), optionally (15:2)-(5:6), optionally (15:2)-(5:5), optionally (15:1)-(5:5), optionally (10:1)-(5:5), optionally (5:1)-(5:5), optionally (15:1)-(5:5). (5:1), optionally (10:1) to (10:3), optionally 15:1, 10:1, 15:2, 5:1, 10:3, 3:1, 5:2, 5:3, 5:4, 5:5, 5:

6.

3. The herbicide composition according to claim 1 or 2, characterized in that, ALS inhibitors are selected from one or more of penoxsulam, pyrimisulfuron, bispyribac-sodium, pyrimisulfuron, bensulfuron-methyl, pyrimisulfuron, chlorpyrifos, pyrimisulfuron-methyl, fluoxetine, flupyrsulfuron-methyl, and promethazine. When herbicide B includes penoxsulam, the weight ratio of oxazolidinone to penoxsulam is (5:1). (1:1), with optional weight ratios of 5:1, 3:1, 5:3 or 1:1; Alternatively, when herbicide B includes flumetsulam, the weight ratio of oxazolidinone to flumetsulam is (5:1) to (1:1), and optionally the weight ratio is 5:1, 3:1, 5:3 or 1:

1. Alternatively, when herbicide B includes pyrimisulfuron, the weight ratio of oxazolidinone to pyrimisulfuron is (15:1) to (5:1), optionally 15:1 or 5:

1. Alternatively, when herbicide B includes bensulfuron-methyl, the weight ratio of oxazolidinone to bensulfuron-methyl is (15:2) to (5:6), and optionally the weight ratio is 15:2, 5:2, 5:4 or 5:

6. Alternatively, when herbicide B includes bispyribac-sodium, the weight ratio of oxazolidinone to bispyribac-sodium is (15:1) to (5:5), and optionally the weight ratio is 15:1, 5:1, 3:1, 5:3 or 1:

1. Alternatively, when herbicide B includes pyrimisulfuron, the weight ratio of oxazolidinone to pyrimisulfuron is (10:1) to (10:3), and optionally the weight ratio is 10:1, 10:2 or 10:

3. Alternatively, when herbicide B includes chlorpyrifos, the weight ratio of oxazolidinone to chlorpyrifos is (15:2) to (5:2), and optionally the weight ratio is 5:2, 5:1 or 15:

2.

4. The herbicide composition according to claim 3, characterized in that, When herbicide B is penoxsulam or fluroxypyr, the weight ratio of herbicide A to herbicide B is (5-15):(1-5), and optionally the weight ratio is 5:1, 3:1, 5:3 or 1:

1. Alternatively, when herbicide B is pyrimisulfuron, the weight ratio of herbicide A to herbicide B is (15:1) to (5:1), and optionally the weight ratio is 15:1 or 5:

1. Alternatively, when herbicide B is bensulfuron-methyl or bispyribac-sodium, the weight ratio of herbicide A to herbicide B is (15:1) to (5:6), optionally (15:2) to (5:5), optionally 15:1, 15:2, 5:1, 3:1, 5:3, 5:2, 5:4, 5:5 or 5:6; Alternatively, when herbicide B is pyrimisulfuron, the weight ratio of herbicide A to herbicide B is (10:1) to (10:3), and optionally the weight ratio is 10:1, 10:2 or 10:3; Alternatively, when herbicide B is chlorpyrifos, the weight ratio of herbicide A to herbicide B is (15:2) to (5:2), and optionally the weight ratio is 5:2, 5:1 or 15:

2.

5. The herbicide composition according to any one of claims 1 to 4, characterized in that, The active ingredient comprises 1-95 wt% of the total weight of the composition, optionally 5%-80 wt%, optionally 6%-45 wt%.

6. The herbicide composition according to any one of claims 1 to 5, characterized in that, The herbicide composition is formulated as a dispersible oil suspension, an aqueous suspension, a suspension emulsion, a wettable powder, an emulsifiable concentrate, a water-dispersible granule, an emulsion, or a microemulsion. And / or, the herbicidal composition further includes an adjuvant selected from one or more of the following: safeners, dispersants, wetting agents, emulsifiers, solvents, cosolvents, antifreeze agents, stabilizers, preservatives, thickeners, binders, defoamers, acid-adjusting media, alkali-adjusting media, and solid inert carriers.

7. The herbicide composition according to claim 6, characterized in that, The safener is selected from one or more of the following: bis(oxazolyl) acid, cyprosulfamide, pyrazolyl glufosinate, quinoline, gibberellic acid, furilazole, and metcamifen; And / or, the dispersant comprises one or more of the following: sodium lignosulfonate, calcium lignosulfonate, sodium polyacrylate, methylene bis(naphthalene) sulfonate, calcium alkylbenzene sulfonate, amine alkylbenzene sulfonate, sodium methylene bis(naphthalene) sulfonate formaldehyde condensate, polyoxyethylene-polyoxypropylene block copolymer, carboxymethyl cellulose, polyvinyl alcohol, polyvinylpyrrolidone, polycarboxylate, alkylnaphthalene sulfonate condensate, etc. And / or, the wetting agent includes one or more of the following: pull-apart powder, sodium dodecyl sulfate, condensate of fatty alcohol and ethylene oxide, fast T, naphthalene sulfonate formaldehyde condensate, alkyl naphthalene sulfonate, aryl polyoxyethylene ether phosphate, alkyl sulfate, sodium alkyl aryl sulfonate, alkylphenol polyoxyethylene ether phosphate, fatty alcohol polyoxyethylene ether, sorbitan fatty acid ester polyoxyethylene ether, azone, and organosilicon wetting agents; And / or, the emulsifier includes one or more of the following: agricultural emulsion 400#, agricultural emulsion 500#, agricultural emulsion 600#, agricultural emulsion 700#, NP series, 0201B, 0203B, 2201, Ningru No. 31, Ningru No. 33, Ningru No. 37, 0202, 0202C, block polyether, alkylphenol polyoxyethylene ether sulfosuccinate, castor oil polyoxyethylene ether, fatty acid polyoxyethylene ether, polyoxyethylene fatty alcohol ether, ethoxylated castor oil, polymethyl acrylate, fatty acid polyethylene glycol ester, glyceryl trilaurate polyoxyethylene ether, etc. And / or, the solvent includes one or more of the following: acetone, butanone, cyclohexanone, toluene, xylene, trimethylbenzene, tetramethylbenzene, methylnaphthalene, methyl oleate, ethyl acetate, fatty acid methyl ester, pine oil, soybean oil, rapeseed oil, biodiesel, ethanol, n-propanol, isopropanol, propylene glycol, glycerol, n-butanol, isooctyl alcohol, sec-butyl acetate, dimethyl carbonate, diesel oil, white oil, engine oil, dibasic ester, N-methylpyrrolidone, N,N-dimethylformamide, isophorone, deionized water, etc. And / or, the cosolvent includes one or more of ethanol, n-propanol, isopropanol, propylene glycol, glycerol, n-butanol, isooctyl alcohol, etc. And / or, the antifreeze includes one or more of sorbitol, ethylene glycol, polyethylene glycol, propylene glycol, glycerol, urea, and sodium chloride; And / or, the stabilizer includes one or more of sodium citrate, resorcinol, epoxidized soybean oil, epichlorohydrin, epoxidized linseed oil, pentaerythritol, xylitol, butylated hydroxyanisole, etc. And / or, the preservative includes one or more of formaldehyde, benzoic acid, sodium benzoate, potassium sorbate, Kathon, isothiazolinone, etc. And / or, the thickener includes one or more of xanthan gum, gelatin, gum arabic, polyvinyl alcohol, bentonite, magnesium aluminum silicate, carboxymethyl cellulose, carboxyethyl cellulose, methyl cellulose, etc. And / or, the binder includes one or more of the following: glucose, sucrose, hydroxyethyl cellulose, soluble starch, polyethylene glycol, methyl cellulose, polycarboxylic acids and water-soluble polymers such as sodium carboxymethyl cellulose, polyvinyl alcohol, paraffin wax, gypsum, hydroxypropyl methyl cellulose, and polyacrylamide. And / or, the defoamer includes one or more of C8-10 fatty alcohol compounds, epoxidized soybean oil, ethanol, silicone compounds, organosilicon oil, and C10-20 saturated fatty acid compounds; And / or, the acid-adjusting medium includes one or more of the following: organic acids such as benzoic acid, citric acid, acetic acid, acetic anhydride, propionic acid, and methanesulfonic acid; and inorganic acids such as hydrochloric acid, sulfuric acid, and phosphoric acid. And / or, the alkali-adjusting medium includes one or more of the following: organic bases such as ethylenediamine, triethylamine, triethanolamine, triisopropanolamine, ammonia, and urea; and inorganic bases or salts such as sodium carbonate, sodium bicarbonate, and sodium hydroxide. And / or, the solid inert carrier includes one or more of the following: light calcium carbonate, diatomaceous earth, bentonite, attapulgite, silica, kaolin, and corn starch.

8. The herbicide composition according to any one of claims 1 to 7, characterized in that, It is used to control one or more of the following: barnyard grass, angelica, sedge, water hyacinth, sedge, crabgrass, duckweed, water amaranth, clove knotweed, sedge, and floating grass; optionally, it can be used to control harmful weeds in paddy fields.

9. The use of a herbicide composition according to any one of claims 1 to 8 in the control of harmful weeds in crop fields.

10. The application according to claim 9, characterized in that, The harmful weeds are one or more of the following: barnyard grass, angelica sinensis, Echinochloa crus-galli, sedge, water hyacinth, sedge, crabgrass, duckweed, water amaranth, clove knotweed, sedge, and floating grass; optionally, they are used for the control of harmful weeds in paddy fields.

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