A sample analyzer

Abstract

The present application relates to a kind of sample analyzers, including identification module, sampling module, liquid drive module, blood sedimentation detection module, blood detection module and controller.Sampling module includes sample needle and sample suction line, and blood sedimentation detection part is configured on sample suction line.Controller controls the first sample to be measured for blood sedimentation detection when detecting the detection item of the sample to be measured is identified to include blood sedimentation detection and blood detection, and the second sample to be measured for blood detection is sucked into isolation section after the first sample to be measured is sucked, so that the first sample to be measured and the second sample to be measured are separated by isolation section in sample suction line.The first sample to be measured can be moved to blood sedimentation detection part for blood sedimentation detection, and the second sample to be measured can be injected into blood detection module for blood detection.The sample analyzer can reduce the amount of blood sample, reduce the risk of sample mixing, and improve the joint detection efficiency of blood sedimentation detection and blood detection.

Description

Technical Field

[0001] This invention relates to the field of blood sample testing technology, and more particularly to a sample analyzer. Background Technology

[0002] In clinical diagnosis, erythrocyte sedimentation rate (ESR) and blood cell count are two of the most common and fundamental hematological examinations. ESR primarily reflects the aggregation state of red blood cells and is associated with inflammation, infection, and autoimmune diseases. Its capillary method requires the blood sample to be left to stand in a capillary tube, and the ESR result is calculated by measuring parameters related to red blood cell aggregation. Blood cell count, on the other hand, requires analysis of a homogeneous, anticoagulated blood sample to obtain parameters such as red blood cells, white blood cells, and platelets.

[0003] In traditional laboratory workflows, these two tests are typically performed by different instruments or on different functional modules of the same large automated equipment. This often requires collecting multiple tubes of blood samples or involves complex manual dispensing and transfer by operators, which not only increases the burden of blood collection for patients but also reduces testing efficiency and introduces potential human error and biosafety risks.

[0004] With the increasing demands for efficiency and refined sample management in laboratory medicine, developing automated combined testing systems that integrate erythrocyte sedimentation rate (ESR) and blood cell count (BCC) tests on a single blood sample has become an important development direction in this field. However, integrating these two tests into a single automated workflow presents significant technical challenges. Particularly in the sample processing stage, how to efficiently and economically manage and distribute samples to meet both the long-term settling requirements of ESR samples and the rapid dispensing requirements of BCC samples within the same aspiration tubing remains a common problem in current technology. Summary of the Invention

[0005] To address the problems of large sample volumes and low detection efficiency in existing technologies where erythrocyte sedimentation rate (ESR) testing and blood testing typically require separate sampling and testing, this invention provides a sample analyzer. This analyzer can obtain a first test sample for ESR testing and a second test sample for blood testing from a blood sample within the same sample tube, and solves the technical problems described in the background art by setting an isolation segment between the first and second test samples.

[0006] To achieve the above objectives, the present invention provides a sample analyzer, including an identification module, a sampling module, a liquid driving module, an erythrocyte sedimentation rate (ESR) detection module, a blood detection module, and a controller.

[0007] The identification module is used to identify the required tests for the sample. These tests may include erythrocyte sedimentation rate (ESR) and blood tests. Blood tests may include at least one of the following: complete blood count (CBC), specific protein analysis, and glycated hemoglobin (HbA1c) analysis. When the blood test is a CBC, blood cell data can be obtained; when the blood test is a specific protein analysis or HbA1c analysis, the corresponding specific protein analysis results and HbA1c results can be obtained.

[0008] The sampling module includes a sample needle, a suction tubing connected to the sample needle, and a sample needle drive device for moving the sample needle. One end of the sample needle is used to insert into the sample tube to draw a first and a second sample to be tested, and the other end is connected to the suction tubing. The first and second samples to be tested can come from the same blood sample in the same sample tube, and are different parts of the same blood sample.

[0009] The liquid drive module is connected to the sampling tubing and provides the driving force for the flow of fluid within the sample needle and sampling tubing. The liquid drive module can drive the first test sample, the isolation section, and the second test sample to move within the sample needle and sampling tubing.

[0010] The erythrocyte sedimentation rate (ESR) detection module includes an ESR detection component. An ESR detection section is configured on the aspiration tubing, and the ESR detection component is used to perform ESR detection on the first sample located within the ESR detection section. By placing the ESR detection section on the aspiration tubing, the first sample can be held in a suitable position for ESR detection within the tubing, eliminating the need to transfer the first sample to a separate ESR detection container, thus simplifying the sample processing procedure.

[0011] The blood testing module is configured to perform blood tests on a second sample. In some embodiments, the blood testing module may include a testing pool and a complete blood count (CBC) device. The testing pool receives the second sample dispensed by the sampling module and provides a CBC testing environment for the second sample. The CBC device performs CBC tests on the second sample in the testing pool. In other embodiments, the blood testing module may also be used to perform specific protein analysis, glycated hemoglobin analysis, or other blood sample-based tests.

[0012] The controller is connected to the identification module, sampling module, liquid driving module, erythrocyte sedimentation rate (ESR) detection module, and blood testing module. The controller is configured to control the operation of the identification module, sampling module, liquid driving module, ESR detection module, and blood testing module.

[0013] When the identification module detects that the test items for the sample include blood testing and erythrocyte sedimentation rate (ESR) testing, the controller controls the sampling module to draw in the isolation section after drawing in the first test sample and before drawing in the second test sample, thus separating the first and second test samples within the sampling tubing. This allows for the simultaneous placement of the first test sample for ESR testing and the second test sample for blood testing within the same sampling tubing, while avoiding the need to directly move the test samples to the ESR testing section, which would otherwise fill the entire sampling tubing with blood sample.

[0014] In some implementations, when the controller controls the sampling module to draw up the first sample to be tested, the liquid drive module drives the drawn-up first sample to the erythrocyte sedimentation rate (ESR) detection section of the sampling tubing for ESR detection. The controller also controls the sampling module to dispense a second sample to be tested into the blood detection module for blood detection.

[0015] In some implementations, an isolation section is provided between the first test sample and the second test sample. The isolation section may be an air isolation section, a diluent isolation section, or a composite isolation section including both an air isolation section and a diluent isolation section.

[0016] When the isolation section is an air isolation section, the controller can control the sampling module's sample needle to draw the first test sample from the sample tube. After drawing the first test sample, the controller controls the sample needle to leave the blood sample in the sample tube and controls the liquid drive module to continue aspiration, so that air enters the aspiration tubing and forms an air isolation section after the first test sample. At the same time, the controller drives the first test sample to move to the erythrocyte sedimentation rate (ESR) detection section of the aspiration tubing for ESR detection. When the first test sample moves to a preset position, the controller controls the sample needle to extend into the sample tube to draw the second test sample. After drawing the second test sample, the controller controls the sampling module to move to the blood detection module and dispense the second test sample for blood detection.

[0017] When the isolation section is a diluent isolation section, the controller can control the sampling module's sample needle to draw the first test sample from the sample tube. After drawing the first test sample, the controller controls the sample needle to draw diluent, so that the diluent enters the aspiration tubing and forms a diluent isolation section after the first test sample. Simultaneously, the controller drives the first test sample to move to the erythrocyte sedimentation rate (ESR) detection section of the aspiration tubing for ESR detection. When the first test sample moves to a preset position, the controller controls the sample needle to extend into the sample tube to draw the second test sample, so that the diluent isolation section is located between the first and second test samples. After drawing the second test sample, the controller controls the sample needle to move to the blood detection module and dispense the second test sample for blood detection.

[0018] When the isolation section is a composite isolation section including an air isolation section and a diluent isolation section, the composite isolation section may include a first air isolation section, a diluent isolation section, and a second air isolation section. The first air isolation section is located between the first test sample and the diluent isolation section, and the second air isolation section is located between the diluent isolation section and the second test sample. Specifically, the first air isolation section isolates the first test sample from the diluent isolation section, and the second air isolation section isolates the diluent isolation section from the second test sample. By setting up a composite isolation section, the possibility of direct contact between the diluent and either the first or second test sample can be reduced, thus minimizing the impact of the diluent on the test results.

[0019] In some implementations, after the sampling module aspirates the first test sample, the isolation section, and the second test sample, the second test sample is closer to the aspiration port of the sample needle than the isolation section. Therefore, when the sampling module dispenses a sample to the blood testing module, the second test sample located closer to the aspiration port of the sample needle can be dispensed preferentially, while the first test sample can still be held in the erythrocyte sedimentation rate (ESR) detection section of the aspiration tubing for ESR testing.

[0020] In some embodiments, a first sample segment is formed within the aspiration tubing of the first sample to be tested. The erythrocyte sedimentation rate (ESR) detection unit includes a heating region for heating the first sample to be tested and a detection region for detecting the ESR of the first sample to be tested. The functional area of ​​the ESR detection unit includes the heating region and the detection region. The length of the first sample segment along the extension direction of the aspiration tubing is greater than the length of the functional area of ​​the ESR detection unit along the extension direction of the aspiration tubing, so that the first sample segment covers both the heating region and the detection region.

[0021] By ensuring that the first sample segment covers the heating area, it is guaranteed that the location corresponding to the heating area is the first sample to be tested, which facilitates sufficient and stable heating of the first sample to be tested. By ensuring that the first sample segment covers the detection area, it is guaranteed that the detection field of view or detection range of the erythrocyte sedimentation rate (ESR) detection component is the first sample to be tested, reducing the risk that the air isolation segment, diluent isolation segment, or the end of the sample segment may enter the detection area and affect the ESR detection results.

[0022] In some embodiments, when the first sample to be tested is located in the erythrocyte sedimentation rate (ESR) detection section, the two ends of the first sample segment extending along the sampling tube are respectively located on both sides of the ESR detection section. Therefore, the entire ESR detection section, or at least its functional area, can be located in the middle region of the first sample segment, thereby further improving the stability of heating and detection.

[0023] In some embodiments, the sample analyzer further includes a heating module. The heating module is connected to the controller and is configured corresponding to the erythrocyte sedimentation rate (ESR) detection unit. The heating module is used to heat the first sample to be tested located at the ESR detection unit. The heating module can preheat the first sample to be tested before ESR detection, or maintain the first sample to be tested within a preset temperature range during ESR detection.

[0024] In some implementations, the controller is configured to: after at least a portion of the first test sample has moved to the erythrocyte sedimentation rate (ESR) detection unit, control the heating module to begin preheating the first test sample located in the ESR detection unit.

[0025] In some implementations, during at least a portion of the time the heating module preheats the first sample to be tested located in the erythrocyte sedimentation rate (ESR) detection section, the controller controls the sampling module to aspirate the isolation section and / or extract the second sample to be tested. That is, the preheating process of the first sample to be tested can at least partially overlap with the isolation section aspiration process and the extraction process of the second sample to be tested, thereby reducing the waiting time before ESR detection.

[0026] The beneficial effects of this invention are as follows: In the sample analyzer provided in this application, the erythrocyte sedimentation rate (ESR) detection unit is located on the sample aspiration line. When the controller recognizes that the test items for the sample include ESR and blood testing, it controls the sampling module to sequentially aspirate the first test sample, the isolation section, and the second test sample. The first test sample is then moved to the ESR detection unit for ESR testing, while the second test sample is dispensed into the blood testing module for blood testing. Thus, combined ESR and blood testing can be performed within the same sample analyzer.

[0027] Because an isolation section is provided between the first and second test samples, the isolation section can separate the two samples, reduce the risk of sample mixing, and occupy at least part of the tubing space in the aspiration line, thereby reducing the amount of blood sample consumed to send the first test sample to the erythrocyte sedimentation rate (ESR) detection section.

[0028] In addition, after the first sample to be tested is moved to the erythrocyte sedimentation rate (ESR) detection unit, ESR preparation or ESR detection can be performed first, and the second sample to be tested can continue to be used for blood testing. This allows the ESR preparation and the aspiration, dispensing or blood testing process of the second sample to be tested to be at least partially parallel, thereby improving the efficiency of joint detection. Attached Figure Description

[0029] Figure 1 This is a schematic block diagram of a sample analyzer according to the present invention; Figure 2 This is a schematic diagram of the structure of a sample analyzer according to the present invention; Figure 3This is a schematic diagram of different implementations of the isolation section of a sample analyzer according to the present invention.

[0030] in, 1-Identification module, 2-Sampling module, 3-Liquid driving module, 4-Erythrocyte sedimentation rate (ESR) detection module, 5-Blood detection module, 6-Controller 21-Sample needle, 22-Aspirator tubing, 23-Dilution buffer isolation section, 24-Air isolation section, 25-Combined isolation section, 251-First air isolation section, 252-Second air isolation section 41-Erythrocyte sedimentation rate (ESR) detection unit; 42-Heating module; 43-Erythrocyte sedimentation rate (ESR) detection components; 44-First sample to be tested. 7-Sample tubes 51 - Second sample to be tested. Detailed Implementation

[0031] The embodiments of the present invention will be described below with reference to the accompanying drawings. It should be understood that the following embodiments are for illustrative purposes only and are not intended to limit the scope of protection of the present invention. Equivalent substitutions or conventional modifications made by those skilled in the art to the structures, processes, parameters, or module combinations in the various embodiments without departing from the concept of the present invention should all fall within the scope of protection of the present invention.

[0032] In the description of this invention, the terms "first," "second," etc., are used only to distinguish different objects and do not indicate a specific order or degree of importance. The "first sample to be tested" and the "second sample to be tested" can originate from the same blood sample within the same sample tube, and are different portions of that blood sample. The first sample to be tested is primarily used for erythrocyte sedimentation rate (ESR) detection, while the second sample to be tested is primarily used for blood tests, such as at least one of complete blood count analysis, specific protein analysis, and glycated hemoglobin analysis.

[0033] When erythrocyte sedimentation rate (ESR) testing and blood testing are performed together, if the ESR testing unit is located on the aspiration tubing, the first sample to be tested needs to be moved from the sample needle aspiration port to the ESR testing unit on the aspiration tubing. Since there is usually a certain volume of tubing between the sample needle aspiration port and the ESR testing unit, relying entirely on blood samples to fill this section of tubing would increase the amount of blood used. Furthermore, ESR testing requires the first sample to meet preheating, settling, or testing requirements at the ESR testing unit, while blood testing requires the timely dispensing of another portion of blood sample to the blood testing module. This makes sample arrangement and fluid control within the same aspiration tubing quite difficult.

[0034] Based on this, this application integrates the erythrocyte sedimentation rate (ESR) detection module and the blood detection module into the same instrument, forming a fluid arrangement of "first sample to be tested – isolation section – second sample to be tested" in the sampling tubing. The first sample to be tested is moved to the ESR detection section on the sampling tubing for ESR detection; the second sample to be tested is located near the sample needle aspiration port and is subsequently dispensed into the blood detection module; the isolation section is located between the first and second samples to be tested. Thus, the isolation section can, on the one hand, separate the first and second samples to be tested, reducing the risk of them mixing within the sampling tubing; on the other hand, it can occupy at least part of the tubing space between the first and second samples to be tested, reducing the amount of blood sample consumed to deliver the first sample to the ESR detection section.

[0035] refer to Figure 1 and Figure 2 This invention provides a sample analyzer, including an identification module 1, a sampling module 2, a liquid driving module 3, an erythrocyte sedimentation rate (ESR) detection module 4, a blood detection module 5, and a controller 6.

[0036] The identification module 1 is used to identify the testing items of the sample to be tested. The identification module 1 can determine whether the current sample to be tested needs to undergo erythrocyte sedimentation rate (ESR) testing and blood testing by reading the barcode, QR code, or RFID tag on the sample tube 7, or by receiving testing item information sent by the laboratory information system.

[0037] The sampling module 2 includes a sample needle 21, a suction tubing 22, and a sample needle drive device. One end of the sample needle 21 is used to insert into the sample tube 7 to draw blood samples, and the other end is connected to the suction tubing 22. The sample needle drive device is used to drive the sample needle 21 to move between the sample tube 7 suction position, the diluent position, and the blood detection module 5.

[0038] The liquid drive module 3 is connected to the aspiration tubing 22 and is used to drive the flow of liquid or gas within the sample needle 21 and the aspiration tubing 22. The liquid drive module 3 can be a syringe pump, plunger pump, negative pressure pump, peristaltic pump, or other device capable of generating aspiration and dissipation driving force. The controller 6 can control the position of each fluid segment within the sample needle 21 and the aspiration tubing 22 by controlling the aspiration volume, dissipation volume, aspiration speed, dissipation speed, or pump stroke of the liquid drive module 3.

[0039] The erythrocyte sedimentation rate (ESR) detection module 4 includes an ESR detection unit 41, a heating module 42, and an ESR detection component 43. The ESR detection unit 41 is mounted on the sample suction line 22. The heating module 42 is positioned corresponding to the ESR detection unit 41 and is used to heat the first sample 44 located within the ESR detection unit 41. The ESR detection component 43 is used to perform ESR detection on the first sample 44 within the ESR detection unit 41. The ESR detection component 43 can employ optical detection methods, such as obtaining ESR results by detecting parameters like changes in erythrocyte aggregation.

[0040] The blood testing module 5 is used to receive the second test sample 51 dispensed by the sampling module 2 and to perform blood testing on the second test sample 51. The blood testing module 5 may include a testing pool and a routine blood count testing device for performing routine blood count analysis; it may also include a specific protein detection device, a glycated hemoglobin detection device, or other blood testing devices.

[0041] The controller 6 is connected to the identification module 1, the sampling module 2, the liquid driving module 3, the erythrocyte sedimentation rate detection module 4, and the blood detection module 5 respectively, and is used to control the coordinated operation of each module.

[0042] When the identification module 1 identifies that the current test items for the sample include erythrocyte sedimentation rate (ESR) and blood testing, the controller 6 controls the sampling module 2 to aspirate the first test sample 44 for ESR and drives it to the ESR detection unit 41 via the liquid drive module 3. Subsequently, the controller 6 controls the sampling module 2 to aspirate the isolation section and then aspirate the second test sample 51 for blood testing. After aspiration, within the aspiration tubing 22, the second test sample 51 is closer to the aspiration port of the sample needle 21 than the isolation section, while the first test sample 44 is closer to the ESR detection unit 41 than the isolation section.

[0043] After the first sample 44 is moved to the erythrocyte sedimentation rate (ESR) detection unit 41, the controller 6 can control the heating module 42 to begin preheating or isothermal treatment of the first sample 44. During at least part of the preheating or ESR detection preparation time, the controller 6 can also control the sampling module 2 to continue performing actions such as isolation section aspiration, second sample 51 aspiration, and second sample 51 dispensing, so that the ESR detection preparation process and the blood sampling or dispensing process are at least partially parallel, improving the efficiency of joint detection.

[0044] The first sample 44 to be tested forms a first sample segment within the aspiration tube 22. The erythrocyte sedimentation rate (ESR) detection unit 41 may include a heating area and a detection area. The heating area is used to heat or maintain the temperature of the first sample 44 to be tested, and the detection area is used for the ESR detection component 43 to perform ESR detection on the first sample 44 to be tested. The heating area and the detection area may at least partially overlap, or they may be arranged adjacently or at intervals along the extension direction of the aspiration tube 22. The functional area of ​​the ESR detection unit 41 may include the heating area and the detection area.

[0045] In some embodiments, the length of the first sample segment extending along the suction line 22 is greater than the length of the functional area of ​​the erythrocyte sedimentation rate (ESR) detection unit 41 extending along the suction line 22, enabling the first sample segment to cover both the heating area and the detection area. Furthermore, when the first sample to be tested 44 is located in the ESR detection unit 41, the two ends of the first sample segment extending along the suction line 22 can be located on opposite sides of the ESR detection unit 41. Thus, the entire ESR detection unit 41 or its functional area can be located in the middle region of the first sample segment, thereby reducing the risk of disturbances at the ends, isolation sections, or interfaces of the first sample segment entering the effective heating area or the effective detection area.

[0046] It should be noted that, in this application, the first sample segment is not required to remain absolutely stationary throughout the entire combined detection process. Since the sampling module 2 also needs to aspirate the isolation segment, absorb the second test sample 51, and dispense the second test sample 51 into the blood detection module 5, the first sample segment may undergo certain positional changes during these fluid operations, depending on the fluid column within the aspiration tubing 22. This positional change can be controlled by the controller 6 through the aspiration volume, discharge volume, pump stroke, and volume of each fluid segment of the liquid drive module 3.

[0047] Specifically, the first sample segment may include a target detection portion for erythrocyte sedimentation rate (ESR) detection and a position margin portion located on one or both sides of the target detection portion. The target detection portion is the part of the first sample segment that is heated by the heating module 42 and subjected to ESR detection by the ESR detection component 43. The position margin portion is not directly used for ESR detection; it is used to provide length margin when the position of the first sample segment changes, making it difficult for the end or isolation section of the first sample segment to enter the effective functional area of ​​the ESR detection unit 41.

[0048] The controller 6 can determine the expected position of the first sample segment within the aspiration tubing 22 based on the aspiration volume of the first sample 44, the volume of the isolation section, the aspiration volume of the second sample 51, the dispensing volume of the second sample 51, the inner diameter of the aspiration tubing 22, and the position of the erythrocyte sedimentation rate (ESR) detection section 41 relative to the aspiration port of the sample needle 21. Therefore, even if the first sample segment shifts during the aspiration of the isolation section, the aspiration of the second sample 51, or the dispensing of the second sample 51, the target detection portion within the first sample segment can be positioned within the heating area during preheating and / or within the detection area during ESR detection.

[0049] In other words, this application does not require the entire length of the first sample segment to participate in the erythrocyte sedimentation rate (ESR) detection, nor does it require the first sample segment to remain completely stationary during the aspiration and dispensing of the second test sample 51. As long as the controller 6 can control the volume of each fluid segment and the movement of the liquid drive module 3 to ensure that the target detection portion in the first sample segment is within the functional area of ​​the ESR detection unit 41 at the required time for ESR detection, the ESR detection requirements can be met. This approach improves the fault tolerance of fluid control and also facilitates the aspiration and dispensing of the second test sample 51 while the first test sample 44 is being preheated or prepared for detection.

[0050] The following is combined Figure 3 The three specific implementation methods of the isolation section are explained.

[0051] Example 1: The isolation section is an air isolation section refer to Figures 1 to 3 In this embodiment, the isolation section between the first test sample 44 and the second test sample 51 is an air isolation section 24.

[0052] When the identification module 1 detects that the blood sample in the sample tube 7 needs to be tested for erythrocyte sedimentation rate (ESR) and blood tests simultaneously, the controller 6 controls the sample needle drive device to drive the sample needle 21 into the sample tube 7. Under the control of the controller 6, the liquid drive module 3 generates a suction force, causing the sample needle 21 to draw a predetermined amount of blood sample from the sample tube 7, forming the first test sample 44.

[0053] After aspirating the first sample 44, the controller 6 controls the sample needle 21 to leave the blood sample in the sample tube 7, for example, by raising the sample needle 21 above the liquid surface in the sample tube 7 or moving it into the air environment. Subsequently, the controller 6 controls the liquid drive module 3 to continue aspiration, allowing air to enter the aspiration tube 22 through the sample needle 21, forming an air isolation section 24 after the first sample 44.

[0054] During the process of being drawn into the air isolation section 24, the air isolation section 24 pushes the first test sample 44 along the suction tube 22, causing the first test sample 44 to gradually move to the erythrocyte sedimentation rate (ESR) detection section 41. When at least a portion of the first test sample 44 is located in the ESR detection section 41, preferably when the target detection portion of the first test sample 44 covers the heating area and detection area of ​​the ESR detection section 41, the controller 6 can control the liquid drive module 3 to stop or reduce suction, so that the first test sample 44 is kept near the ESR detection section 41.

[0055] At this time, the controller 6 can control the heating module 42 to preheat or keep the temperature of the first sample 44 to be tested located in the erythrocyte sedimentation rate (ESR) detection unit 41, and control the ESR detection component 43 to perform ESR detection on the first sample 44 to be tested at a preset time.

[0056] Subsequently, the controller 6 controls the sample needle drive device to drive the sample needle 21 to re-enter the sample tube 7, and the liquid drive module 3 continues to aspirate, causing the sample needle 21 to draw the second sample 51 from the sample tube 7. After aspiration, in the aspiration tubing 22, from the aspiration port of the sample needle 21 towards the inside of the tubing, the second sample 51, the air isolation section 24, and the first sample 44 are arranged in sequence. That is, the second sample 51 is closer to the aspiration port of the sample needle 21 than the air isolation section 24, and the first sample 44 is located on the side of the air isolation section 24 away from the aspiration port of the sample needle 21, and is located at or near the erythrocyte sedimentation rate (ESR) detection section 41.

[0057] Subsequently, the controller 6 controls the sample needle 21 to move to the blood detection module 5, and controls the liquid drive module 3 to discharge the second test sample 51 near the suction port of the sample needle 21, so that the second test sample 51 is dispensed into the blood detection module 5. The blood detection module 5 performs blood tests on the second test sample 51, such as complete blood count analysis, specific protein analysis, or glycated hemoglobin analysis.

[0058] During the aspiration and / or dispensing of the second sample 51, the first sample segment may undergo a certain positional change due to the fluid column within the aspiration tubing 22. The controller 6 can control this positional change based on the volume of the air isolation section 24, the aspiration volume of the second sample 51, and the dispensing volume, ensuring that the target detection portion of the first sample segment is located within the heating area during preheating and / or within the detection area during erythrocyte sedimentation rate (ESR) testing. The positional margin at both ends of the first sample segment can be used to absorb the effects of the aforementioned positional change, reducing the risk of the air isolation section 24 entering the effective detection area of ​​the ESR detection unit 41.

[0059] In this embodiment, the air isolation section 24 can separate the first test sample 44 and the second test sample 51, reducing the risk of the two blood samples mixing in the aspiration tubing 22. At the same time, the air isolation section 24 occupies part of the tubing volume between the first test sample 44 and the second test sample 51, so that the tubing space between the sample needle 21 and the erythrocyte sedimentation rate detection section 41 does not need to be completely filled by blood sample, thereby reducing the amount of blood sample required for joint detection.

[0060] Example 2: The isolation section is a diluent isolation section. refer to Figures 1 to 3 In this embodiment, the isolation section between the first test sample 44 and the second test sample 51 is the diluent isolation section 23.

[0061] When the identification module 1 recognizes that the blood sample in the sample tube 7 needs to be tested for erythrocyte sedimentation rate and blood test at the same time, the controller 6 controls the sample needle 21 to extend into the sample tube 7 and controls the liquid drive module 3 to draw aspiration, so that the sample needle 21 draws a predetermined amount of the first test sample 44 from the sample tube 7.

[0062] After aspirating the first sample 44, the controller 6 moves the sample needle 21 to the diluent location. This diluent location can be a diluent container, a diluent pool, a diluent supply port, or a location in the blood testing module 5 used to provide the diluent. Subsequently, the controller 6 controls the liquid drive module 3 to continue aspirating, causing the diluent to enter the aspiration tubing 22 via the sample needle 21, forming a diluent isolation section 23 after the first sample 44.

[0063] During the aspiration of the diluent isolation section 23, the diluent isolation section 23 pushes the first test sample 44 along the aspiration tube 22, causing the first test sample 44 to move to the erythrocyte sedimentation rate (ESR) detection section 41. When the first test sample 44 reaches the preset position, the controller 6 controls the liquid drive module 3 to stop or adjust the aspiration state. The preset position can be the position where the target detection part of the first test sample 44 covers the detection area of ​​the ESR detection section 41, or it can be the position where the target detection part simultaneously covers both the heating area and the detection area of ​​the ESR detection section 41.

[0064] After the first sample to be tested 44 is located in the erythrocyte sedimentation rate (ESR) detection unit 41, the controller 6 can control the heating module 42 to start preheating the first sample to be tested 44. After the preheating treatment of the first sample to be tested 44 is completed, the controller controls the ESR detection component 43 to perform ESR detection on the first sample to be tested 44.

[0065] During at least a portion of the preheating period of the first sample 44, the controller 6 can control the sample needle 21 to re-insert into the sample tube 7 and control the liquid drive module 3 to continue aspiration, causing the sample needle 21 to aspirate the second sample 51. After aspiration, within the aspiration tubing 22, from the aspiration port of the sample needle 21 towards the interior of the tubing, are the second sample 51, the diluent isolation section 23, and the first sample 44. The diluent isolation section 23 is located between the first sample 44 and the second sample 51, serving to separate the two blood samples.

[0066] The controller 6 controls the sample needle 21 to move to the blood detection module 5, and controls the liquid drive module 3 to dispense the second test sample 51 into the blood detection module 5. The blood detection module 5 performs corresponding blood tests on the second test sample 51.

[0067] In this embodiment, the length of the first sample segment can be greater than the length of the functional area of ​​the erythrocyte sedimentation rate (ESR) detection unit 41. The middle area of ​​the first sample segment serves as the target detection portion, and the two side areas serve as positional margin portions. When the controller 6 aspirates the diluent isolation section 23, aspirates the second test sample 51, or dispenses the second test sample 51, the first sample segment can undergo controlled displacement. By controlling the volume of the diluent isolation section 23, the aspirated amount of the second test sample 51, and the dispensing amount, the controller 6 ensures that the target detection portion is within the functional area of ​​the ESR detection unit 41 during preheating and / or detection. Thus, even if there is an interface between the first test sample 44 and the diluent isolation section 23, the interface can be located outside the functional area, or at least prevented from entering the effective detection area.

[0068] In this embodiment, the diluent isolation section 23 forms a liquid barrier between the first test sample 44 and the second test sample 51. Compared to completely filling the tubing with blood samples, the diluent isolation section 23 can replace part of the blood sample in the tubing volume, thereby reducing blood sample consumption. Using a diluent isolation section avoids the problems associated with using an air isolation section. When the isolation section is an air isolation section 24, the liquid driven by the liquid drive device 3 to move the liquid in the aspiration tubing 22 may lead to inaccurate liquid movement, especially during the aspiration of the second test sample 51. The air isolation section 24 may cause inaccurate aspiration of the second test sample 51 or inaccurate sample dispensing after aspiration, ultimately affecting the final test results. Using a diluent as the isolation section allows for more precise control of the movement of the first test sample 44 and the second test sample 51 within the aspiration tubing 22, reducing detection problems caused by inaccurate liquid movement. However, using an air isolation section 24 is faster than using a diluent isolation section 23. The action of removing blood sample and aspirating diluent with sample needle 21 has been reduced. Sample needle 21 can aspirate the air isolation section simply by leaving the blood sample.

[0069] Example 3: The isolation section is a composite isolation section refer to Figures 1 to 3 In this embodiment, the isolation segment between the first test sample 44 and the second test sample 51 is a composite isolation segment 25. The composite isolation segment 25 includes a first air isolation segment 251, a diluent isolation segment 23, and a second air isolation segment 252. The first air isolation segment 251 is located between the first test sample 44 and the diluent isolation segment 23, and the second air isolation segment 252 is located between the diluent isolation segment 23 and the second test sample 51.

[0070] When the identification module 1 recognizes that the blood sample in the sample tube 7 needs to be tested for erythrocyte sedimentation rate and blood test at the same time, the controller 6 controls the sample needle 21 to be inserted into the sample tube 7 and controls the liquid drive module 3 to draw up the first sample to be tested 44.

[0071] After aspirating the first test sample 44, the controller 6 controls the sample needle 21 to leave the blood sample in the sample tube 7 and controls the liquid drive module 3 to continue drawing air, allowing air to enter the suction line 22, forming a first air isolation section 251 after the first test sample 44. Subsequently, the controller 6 controls the sample needle 21 to move to the diluent position and controls the liquid drive module 3 to draw diluent, allowing the diluent to enter the suction line 22, forming a diluent isolation section 23 after the first air isolation section 251. Then, the controller 6 again controls the sample needle 21 to leave the diluent and controls the liquid drive module 3 to draw air, allowing air to enter the suction line 22, forming a second air isolation section 252 after the diluent isolation section 23.

[0072] During the sequential formation of the first air isolation section 251, the diluent isolation section 23, and the second air isolation section 252, the composite isolation section 25 pushes the first sample to be tested 44 along the sampling tube 22, causing the first sample to be tested 44 to move to the erythrocyte sedimentation rate (ESR) detection section 41. When at least a portion of the first sample to be tested 44 is located in the ESR detection section 41, preferably when the target detection portion of the first sample to be tested 44 covers the heating area and the detection area of ​​the ESR detection section 41, the controller 6 can control the heating module 42 to preheat or maintain a constant temperature for the first sample to be tested 44, and control the ESR detection component 43 to perform ESR detection on the first sample to be tested 44.

[0073] After the composite isolation section 25 is formed, the controller 6 controls the sample needle 21 to re-enter the sample tube 7 and controls the liquid drive module 3 to aspirate the second sample 51. After aspiration, in the aspiration tube 22, from the aspiration port of the sample needle 21 towards the inside of the tube, the sequence is: the second sample 51, the second air isolation section 252, the diluent isolation section 23, the first air isolation section 251, and the first sample 44. That is, the composite isolation section 25 is located between the first sample 44 and the second sample 51, wherein the first air isolation section 251 is used to isolate the first sample 44 and the diluent isolation section 23, and the second air isolation section 252 is used to isolate the diluent isolation section 23 and the second sample 51.

[0074] After the first test sample 44, the second test sample 51, and the composite isolation section 25 are aspirated into place, the controller 6 controls the sample needle 21 to move to the blood detection module 5, and controls the liquid drive module 3 to dispense the second test sample 51 into the blood detection module 5. The blood detection module 5 performs blood tests on the second test sample 51. At the same time, the first test sample 44 can continue to be preheated, left to stand, or subjected to erythrocyte sedimentation rate (ESR) testing at the ESR detection section 41.

[0075] In this embodiment, the sampling tube 22 can form a fluid segment arrangement consisting of a first sample to be tested 44, a first air isolation section 251, a diluent isolation section 23, a second air isolation section 252, and a second sample to be tested 51. For ease of description, the first sample to be tested 44 can be referred to as the first sample segment S1, the first air isolation section 251 as A1, the diluent isolation section 23 as D1, the second air isolation section 252 as A2, and the second sample to be tested 51 as the second sample segment S2. Depending on the observation direction, the fluid segment in the sampling tube 22 can be represented as S1-A1-D1-A2-S2, or as S2-A2-D1-A1-S1 from the suction port of the sample needle 21 into the tube.

[0076] The controller 6 can control the position of the first sample segment S1 within the aspiration tubing 22 based on the preset volumes of A1, D1, A2, S1, and S2, as well as the dispensing volume of the second sample 51 to be tested. Specifically, the first sample segment S1 includes a target detection section and a position margin section. During the aspiration of A1, D1, A2, and S2, the first sample segment S1 is pushed to the erythrocyte sedimentation rate (ESR) detection section 41; during the dispensing of S2, the first sample segment S1 may undergo a certain positional change due to pressure changes or fluid column movement within the tubing. The controller 6 controls the aspiration and dispensing volume of the liquid drive module 3 to keep this positional change within a preset range, thereby ensuring that the target detection section is located within the functional area of ​​the ESR detection section 41 during preheating and detection.

[0077] In this embodiment, the composite isolation section 25 can occupy a larger tubing volume through the diluent isolation section 23 to reduce blood sample consumption, and can also prevent the diluent isolation section 23 from directly contacting the first test sample 44 and the second test sample 51 through the first air isolation section 251 and the second air isolation section 252 respectively, thereby further reducing the impact of the diluent on the erythrocyte sedimentation rate (ESR) detection and blood test results. This method is particularly suitable for scenarios where the tubing volume between the sample needle 21 and the ESR detection section 41 is large, using only an air isolation section is not conducive to stable fluid control, or where it is desirable to further reduce the risk of mixing between the diluent and the blood sample while reducing blood sample consumption.

[0078] Example 4: Control method of parallel injection of erythrocyte sedimentation rate preheating and second test sample In any of the above embodiments, the controller 6 can control the heating module 42 to start preheating the first test sample 44 after at least a portion of the first test sample 44 has moved to the erythrocyte sedimentation rate (ESR) detection unit 41. At this time, the sampling module 2 does not need to wait for the ESR preheating to be completed, but can continue to perform at least one of the following operations: isolation segment inhalation, aspiration of the second test sample 51, or dispensing of the second test sample 51.

[0079] For example, after the first test sample 44 moves to the erythrocyte sedimentation rate (ESR) detection unit 41 and begins preheating, the controller 6 controls the sample needle 21 to move to the sample tube 7 to aspirate the second test sample 51. Subsequently, the controller 6 controls the sample needle 21 to move to the blood testing module 5, dispensing the second test sample 51 into the detection pool or reaction pool. After receiving the second test sample 51, the blood testing module 5 can perform routine blood tests, specific protein tests, glycated hemoglobin tests, or other blood tests.

[0080] During at least a portion of the time that the second test sample 51 is aspirated, transferred, and dispensed, the first test sample 44 can be in a preheating state, a static state, or a state ready for erythrocyte sedimentation rate (ESR) testing. Therefore, this application can at least partially overlap the originally sequentially executed ESR preheating waiting time and blood sampling and dispensing time, thereby shortening the total time for combined testing.

[0081] During this process, the first sample segment can remain relatively stable or undergo controlled displacement. The controller 6 can determine the position of the first sample segment within the aspiration tubing 22 using a pre-established volume-position correspondence. For example, the controller 6 can calculate or look up the current or expected position of the first sample segment based on the pump stroke of the liquid drive module 3, the cross-sectional area of ​​the aspiration tubing 22, the tubing volume from the sample needle 21 to the erythrocyte sedimentation rate (ESR) detection unit 41, the volume of each isolation section, and the dispensing volume. When it is determined that the target detection portion in the first sample segment is located within the heating area and / or the detection area, the controller 6 allows preheating or ESR detection to continue; when position adjustment is required, the controller 6 can control the liquid drive module 3 to perform small-volume aspiration or dispensing, so that the target detection portion returns to or remains within the functional area of ​​the ESR detection unit 41.

[0082] Through the above control method, this application can meet two requirements: firstly, the first sample to be tested 44 can meet the requirements of preheating and ESR detection at the ESR detection section 41 on the sampling tube 22; secondly, the second sample to be tested 51 can be promptly dispensed into the blood detection module 5 for blood detection. Thus, while reducing the amount of blood sample used, the combined detection efficiency of ESR detection and blood detection is improved.

[0083] In the above embodiments, the volume of the isolation section, the volume of the first sample to be tested 44, and the volume of the second sample to be tested 51 can be preset according to parameters such as the inner diameter of the aspiration tube 22, the length of the tube between the sample needle 21 and the erythrocyte sedimentation rate (ESR) detection section 41, the length of the functional area of ​​the ESR detection section 41, and the sample volume required by the blood detection module 5, and are realized by the controller 6 controlling the aspiration volume of the liquid drive module 3. Through the above method, this application can complete ESR detection and blood detection using blood samples in the same sample tube 7 in the same sample analyzer, reducing sample volume, lowering the risk of sample mixing, and improving the efficiency of combined detection.

[0084] Example 5: The first sample to be tested is kept still during the heating process of the erythrocyte sedimentation rate (ESR) detection section by means of a branch pipeline.

[0085] Based on any of the above embodiments, in some other embodiments, the sampling tubing 22 may include a main tubing and branch tubing connected to the main tubing. The branch tubing may serve as an erythrocyte sedimentation rate (ESR) detection branch, with an ESR detection unit 41 disposed on the branch tubing. The heating module 42 and the ESR detection assembly 43 are disposed corresponding to the ESR detection unit 41 on the branch tubing to heat, allow to stand, and perform ESR detection on the first sample 44 entering the branch tubing.

[0086] The main pipeline can be connected to the sample needle 21 for drawing the first test sample 44, the isolation section, and the second test sample 51, and for dispensing the second test sample 51 into the blood detection module 5. One or both ends of the branch pipeline are connected to the main pipeline. The sample analyzer may also include a valve assembly connected to the controller 6 for controlling the connection or disconnection between the main pipeline and the branch pipelines. The valve assembly may include a three-way valve, a switching valve, a pinch valve, a shut-off valve, or a combination of multiple valves.

[0087] In this embodiment, when the identification module 1 identifies that the current test items for the sample include erythrocyte sedimentation rate (ESR) and blood tests, the controller 6 controls the sample needle 21 to extend into the sample tube 7 and controls the liquid drive module 3 to draw up the first test sample 44. Subsequently, the controller 6 controls the valve assembly to switch to a state that connects the main pipeline and the branch pipeline, and controls the liquid drive module 3 to introduce the first test sample 44 into the branch pipeline, so that at least a portion of the first test sample 44, preferably its target detection portion, is located in the ESR detection section 41 on the branch pipeline.

[0088] When the first test sample 44 moves to the erythrocyte sedimentation rate (ESR) detection unit 41, the controller 6 controls the valve assembly to close or disconnect the fluid connection between the branch pipeline and the main pipeline, so that the first test sample 44 located in the branch pipeline remains stationary or essentially stationary during the heating process. At this time, the controller 6 controls the heating module 42 to preheat or maintain a constant temperature for the first test sample 44 in the branch pipeline, and can control the ESR detection assembly 43 to perform ESR detection on the first test sample 44 after a preset time.

[0089] While the first test sample 44 is being preheated, left to stand, or subjected to erythrocyte sedimentation rate (ESR) testing within the branch pipeline for at least a portion of the time, the main pipeline can continue to perform subsequent fluid operations. Specifically, the controller 6 can control the sample needle 21 to aspirate into the isolation section and further control the sample needle 21 to draw the second test sample 51 from the sample tube 7. Subsequently, the controller 6 controls the sample needle 21 to move to the blood detection module 5 and controls the liquid drive module 3 to dispense the second test sample 51 into the blood detection module 5 for complete blood count analysis, specific protein analysis, glycated hemoglobin analysis, or other blood tests.

[0090] Therefore, the first test sample 44 is relatively independently held at the erythrocyte sedimentation rate (ESR) detection unit 41 within the branch pipeline, while the second test sample 51 is aspirated and dispensed into the blood testing module 5 within the main pipeline. Since the branch pipeline can be isolated by a valve assembly after the first test sample 44 enters the ESR detection unit 41, subsequent operations in the main pipeline, such as the aspiration isolation section, aspiration of the second test sample 51, and dispensing of the second test sample 51, will not, or will minimally, cause any change in the position of the first test sample 44 within the branch pipeline. This allows the first test sample 44 to remain stationary or essentially stationary during heating, settling, and testing, thereby improving the stability of the ESR detection.

[0091] In some embodiments, the volume of the branch pipeline can be greater than or equal to the volume of the first test sample 44 required for erythrocyte sedimentation rate (ESR) testing. The ESR detection section 41 on the branch pipeline may include a heating area and a detection area. The first test sample 44 forms a first sample segment within the branch pipeline. The length of the first sample segment can be greater than the functional area lengths of the heating area and the detection area, so that the first sample segment covers the functional area of ​​the ESR detection section 41. Furthermore, the two ends of the first sample segment along the extension direction of the branch pipeline can be located on both sides of the ESR detection section 41 to reduce the influence of the sample segment ends, gas-liquid interfaces, or other fluid interfaces on heating and detection.

[0092] In some embodiments, the branch pipeline can be a blind-end branch. After the first test sample 44 is pushed into the blind-end branch, the controller 6 controls the valve assembly to close the branch inlet, keeping the first test sample 44 within the blind-end branch. The heating module 42 and the erythrocyte sedimentation rate (ESR) detection assembly 43 are respectively provided on the ESR detection section 41 on the blind-end branch. This method has a simple structure and facilitates keeping the first test sample 44 stationary during the ESR detection process.

[0093] In other embodiments, the branch pipeline can also be a bypass branch connected to the main pipeline at both ends. Valves are installed at both ends of the branch pipeline, and the controller 6 can close the valves at both ends of the branch pipeline after the first sample 44 enters the branch pipeline, thus confining the first sample 44 within the branch pipeline. This method can more stably restrict the position of the first sample 44 and reduce the impact of changes in fluid pressure in the main pipeline on the first sample 44.

[0094] In this embodiment, the isolation section can still be an air isolation section 24, a diluent isolation section 23, or a composite isolation section 25 including a first air isolation section 251, a diluent isolation section 23, and a second air isolation section 252. The isolation section can be formed within the main pipeline and located on the fluid path between the branch pipeline where the first sample to be tested 44 is located and the second sample to be tested 51, or it can be used to separate the residual liquid section after the first sample to be tested 44 is transferred from the second sample to be tested 51 within the main pipeline. The branch pipeline is part of the sampling pipeline 22, the first sample to be tested 44 is located within the branch pipeline, the second sample to be tested 51 is located within the main pipeline, and the isolation section is located between the second sample to be tested 51 and the inlet of the branch pipeline, or between the second sample to be tested 51 and the fluid path where the first sample to be tested 44 is located, thus still separating the first sample to be tested 44 and the second sample to be tested 51 within the sampling pipeline 22 by the isolation section. By coordinating the isolation section and branch pipelines, the amount of blood sample used can be reduced while ensuring that the first sample to be tested 44 meets the requirements of erythrocyte sedimentation rate (ESR) testing for standing, preheating, and testing stability.

[0095] This embodiment differs from the aforementioned controlled displacement method in that, in the former, the first sample to be tested 44 can undergo controlled displacement along with the fluid column within the aspiration tube 22, and the controller 6 keeps the target detection portion within the functional area of ​​the erythrocyte sedimentation rate (ESR) detection unit 41 by controlling the displacement range; however, in this embodiment, after the first sample to be tested 44 enters the branch tube, the branch tube is isolated by a valve assembly, keeping the first sample to be tested 44 stationary or substantially stationary during heating and detection. Both methods ensure that the first sample to be tested 44 is located within the ESR detection unit 41 at the required time for ESR detection, and both methods allow the preheating or detection preparation process of the first sample to be tested 44 to be at least partially parallel to the aspiration, dispensing, or blood detection process of the second sample to be tested 51.

[0096] In the above embodiments, the descriptions of each embodiment have different focuses. For parts not described in detail in a certain embodiment, please refer to the relevant descriptions in other embodiments.

[0097] The sample analyzer provided in the embodiments of this application has been described in detail above. Specific examples have been used to illustrate the principles and implementation methods of this application. The description of the above embodiments is only for the purpose of helping to understand the technical solutions and core ideas of this application. Those skilled in the art should understand that they can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. These modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application.

Claims

1. A sample analyzer, characterized in that, include: The identification module is used to identify the detection items of the sample to be tested. The sampling module includes a sample needle, a suction tube connected to the sample needle, and a sample needle driving device for moving the sample needle; one end of the sample needle is used to insert into the sample tube to draw a first sample to be tested and a second sample to be tested, and the other end is connected to the suction tube. A liquid drive module, which is connected to the sample suction line to provide driving force for the flow of fluid within the sample needle and the sample suction line; The erythrocyte sedimentation rate (ESR) detection module includes an ESR detection component; an ESR detection section is configured on the sampling tube, and the ESR detection component is used to perform ESR detection on the first sample to be tested on the ESR detection section of the sampling tube. A blood testing module, configured to perform blood testing on the second test sample to obtain blood testing data of the second test sample; The controller is configured to control the identification module, sampling module, liquid driving module, erythrocyte sedimentation rate (ESR) detection module, and blood detection module. When the identification module identifies that the test items of the sample to be tested include blood testing and erythrocyte sedimentation rate testing, the controller controls the sampling module to draw in the isolation section after drawing in the first sample to be tested and before drawing in the second sample to be tested, so that the first sample to be tested and the second sample to be tested are separated by the isolation section in the sampling tube.

2. The sample analyzer according to claim 1, characterized in that, When the sampling module picks up the first sample to be tested, the controller controls the liquid driving module to drive the picked-up first sample to be tested to the erythrocyte sedimentation rate (ESR) detection section of the sampling tube for the ESR detection component to perform ESR detection. The controller controls the sampling module to dispense the second sample to be tested into the blood detection module for blood testing.

3. The sample analyzer according to claim 1, characterized in that, The first test sample and the second test sample are separated by an isolation section; the isolation section is an air isolation section, a diluent isolation section, or a composite isolation section including an air isolation section and a diluent isolation section.

4. A sample analyzer according to claim 3, characterized in that, When the isolation section is an air isolation section, the controller is configured to: The sampling module controls the sampling needle to draw the first test sample from the sample tube. After drawing the first test sample, the sampling needle is controlled to leave the blood sample in the sample tube, and the liquid driving module is controlled to continue to draw, so that air enters the aspiration tube and forms the air isolation section after the first test sample. At the same time, the first test sample is driven to move to the erythrocyte sedimentation rate (ESR) detection section of the aspiration tube for the ESR detection component to perform ESR detection. When at least a portion of the first test sample moves to a preset position, the controller controls the sample needle to extend into the sample tube to aspirate the second test sample; after aspirating the second test sample, the controller controls the sampling module to move to the blood detection module to dispense the second test sample for blood detection; When the isolation section is a diluent isolation section, the controller is configured to: The sampling module controls the sample needle to draw the first test sample from the sample tube, and after drawing the first test sample, controls the sample needle to draw diluent so that the diluent enters the aspiration tubing and forms the diluent isolation section after the first test sample; at the same time, it drives the first test sample to move to the erythrocyte sedimentation rate (ESR) detection section of the aspiration tubing so that the ESR detection component can perform ESR detection. When the first sample to be tested moves to the preset position, the controller controls the sample needle to extend into the sample tube to draw up the second sample to be tested, so that the diluent isolation section is located between the first sample to be tested and the second sample to be tested; After aspirating the second test sample, the sample needle is controlled to move to the blood detection module to dispense the second test sample for blood testing; When the isolation section is a composite isolation section including an air isolation section and a diluent isolation section, the composite isolation section includes a first air isolation section, a diluent isolation section, and a second air isolation section; The first air isolation section is located between the first test sample and the diluent isolation section; the second air isolation section is located between the diluent section and the second test sample. The first air isolation section is used to isolate the first test sample and the diluent isolation section; The second air isolation section is used to isolate the diluent isolation section and the second sample to be tested.

5. A sample analyzer according to claim 3, characterized in that, The controller is configured to control the sampling module to sequentially absorb air, diluent, and air after absorbing the first test sample to form a first air isolation section, a diluent isolation section, and a second air isolation section, and to absorb the second test sample after forming the composite isolation section.

6. A sample analyzer according to claim 1, characterized in that, The first test sample and the second test sample are from the same blood sample in the same sample tube, and are different parts of the same blood sample.

7. A sample analyzer according to claim 1, characterized in that, The blood testing module performs blood tests selected from at least one of the following groups: complete blood count analysis, specific protein analysis, and glycated hemoglobin analysis.

8. A sample analyzer according to claim 1, characterized in that, The blood testing module includes a testing pool and a routine blood test device. The testing pool is used to receive the second test sample dispensed by the sampling module and to provide a routine blood test environment for the second test sample. The routine blood test device is used to perform routine blood tests on the second test sample in the testing pool.

9. A sample analyzer according to claim 1, characterized in that, After the sampling module absorbs the first sample to be tested, the isolation section, and the second sample to be tested, the second sample to be tested is closer to the suction port of the sample needle than the isolation section.

10. A sample analyzer according to claim 1, characterized in that, The first sample to be tested forms a first sample segment in the sampling tube, and the erythrocyte sedimentation rate (ESR) detection unit includes a heating area for heating the first sample to be tested and a detection area for detecting the ESR of the first sample to be tested. The length of the first sample segment extending along the sampling tube is greater than the length of the functional area of ​​the erythrocyte sedimentation rate (ESR) detection unit extending along the sampling tube. The functional area includes the heating area and the detection area, so that the first sample segment covers the heating area and the detection area.

11. A sample analyzer according to claim 10, characterized in that, When the first sample to be tested is located in the erythrocyte sedimentation rate (ESR) detection section, the two ends of the first sample segment along the extension direction of the sampling tube are respectively located on both sides of the ESR detection section.

12. A sample analyzer according to claim 1, characterized in that, The sample analyzer also includes a heating module, which is connected to the controller and is configured corresponding to the erythrocyte sedimentation rate (ESR) detection unit. The heating module is used to heat the first sample to be tested located in the ESR detection unit.

13. A sample analyzer according to claim 12, characterized in that, The controller is configured to control the heating module to begin preheating the first sample to be tested located in the erythrocyte sedimentation rate (ESR) detection unit after at least a portion of the first sample to be tested has moved to the ESR detection unit.

14. A sample analyzer according to claim 13, characterized in that, The controller is configured to: control the heating module to start preheating after at least a portion of the first test sample is located in the erythrocyte sedimentation rate (ESR) detection section; and control the sampling module to perform at least one operation in the blood detection module during at least a portion of the preheating time, such as inhaling the isolation section, aspirating the second test sample, or dispensing the second test sample into the blood detection module.

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