Reagent antibody diluter

The reagent antibody diluter addresses the cleaning challenges of existing designs by employing a stirring mechanism with a sleeve and bevel gears for synchronous rotation and movement, ensuring efficient stirring and easy cleaning.

CN222131632UActive Publication Date: 2024-12-10SHANDONG BOREKE BIOTECHNOLOGY CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202420319569.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-02-21
Publication Date
2024-12-10
Estimated Expiration
2034-02-21

AI Technical Summary

Technical Problem

Existing antibody diluters require extensive cleaning due to the reciprocating screw, gear, and rack components coming into contact with the reagent, leading to potential contamination and increased maintenance workload.

Method used

A reagent antibody diluter with a stirring mechanism comprising a sleeve, center rod, bevel gears, and a hydraulic cylinder that allows for synchronous rotation and movement, ensuring the stirring blades rotate without contacting the reagent, thus maintaining a smooth surface for easy cleaning.

Benefits of technology

The design reduces the cleaning workload by preventing reagent adherence and facilitating efficient stirring and dilution, maintaining a smooth surface for easy cleaning.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN222131632U_ABST
    Figure CN222131632U_ABST
Patent Text Reader

Abstract

The utility model provides a reagent antibody diluter and relates to the field of medical instruments. A reagent antibody diluter comprises a dilution cylinder which is connected with a stirring mechanism. The stirring mechanism comprises a sleeve which penetrates through the top of the diluting barrel and is in sliding connection with the diluting barrel, a mechanism shell fixedly connected to the bottom of the sleeve, a center rod rotationally arranged on the inner side of the sleeve and a third bevel gear fixedly connected to the bottom end of the center rod; the rotating shaft is rotationally arranged on the side wall of the mechanism shell, the fourth bevel gear is fixedly connected to the end of the rotating shaft and meshed with the third bevel gear, a lifting plate is rotationally connected to the top end of the sleeve, a hydraulic cylinder is fixedly connected between the lifting plate and the dilution barrel, and the top end of the center rod extends out of the top of the sleeve and is fixedly connected with a U-shaped frame; and a rotating assembly matched with the sleeve is arranged on the lifting plate. The gears do not make contact with reagents, the surfaces of the sleeve and the mechanism shell are smooth, the reagents are not prone to being attached to the sleeve and the mechanism shell, cleaning is easy, and the workload of follow-up cleaning is greatly reduced.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The utility model provides a reagent antibody diluter, which relates to the field of medical instruments. Background Art

[0002] Antibodies are protective proteins produced by the body in response to antigen stimulation. They are large Y-shaped proteins secreted by plasma cells and used by the immune system to identify and neutralize foreign substances such as bacteria and viruses. During the antigen-antibody reaction, antibodies need to be diluted to match the antigen.

[0003] When diluting antibodies, antibody diluters are usually used. Existing antibody diluters, such as a reagent antibody diluter disclosed in the patent with publication number CN219502658U, in order to solve the problem of difficulty in fully stirring antibodies, the above patent has a reciprocating screw fixedly connected under the transmission rod, and the outer wall of the reciprocating screw is threadedly connected with a transmission plate, a stirring shaft is installed on one side of the transmission plate, and stirring blades are fixedly connected on the upper and lower sides of the stirring shaft, a rack is installed on one side of the stirring shaft, and a gear is installed at the front end of the rack. The transmission plate is driven up and down by the reciprocating screw, and the transmission plate drives the stirring shaft to move up and down, and at the same time, the stirring shaft is driven to rotate under the action of the gear and the rack.

[0004] However, the above patent arranges the reciprocating screw, gear and rack on the inner side of the diluter body. When diluting the antibody, the reciprocating screw, gear and rack will come into contact with the reagent. Since the surfaces of the reciprocating screw, gear and rack are uneven and there are many grooves on them, the thread transmission and gear transmission are also precision transmissions. Once impurities adhere to the surface, it is likely to affect the use. For some relatively viscous liquids, they may adhere to the thread grooves of the reciprocating screw and the tooth grooves of the gears and racks. In order to ensure the normal use of each component, a relatively thorough cleaning work must be carried out after each use, which is quite troublesome. For this reason, we propose a reagent antibody diluter. Utility Model Content

[0005] The technical problem to be solved by the utility model is that the existing stirring mechanism has a large workload for subsequent cleaning because the reciprocating screw, gears and gears are all in contact with the reagent.

[0006] To solve the above technical problems, the technical solution provided by the utility model is: a reagent antibody diluter, comprising a dilution cylinder, which is connected to a stirring mechanism, and the stirring mechanism comprises a sleeve that passes through the top of the dilution cylinder and is slidably connected to the dilution cylinder, a mechanism shell fixed to the bottom of the sleeve, a center rod rotatably arranged on the inner side of the sleeve, a bevel gear three fixed to the bottom end of the center rod, a rotating shaft rotatably arranged on the side wall of the mechanism shell, and a bevel gear four fixed to the end of the rotating shaft and meshing with the bevel gear three, the bevel gear three and the bevel gear four are both arranged on the inner side of the mechanism shell, the top end of the sleeve is rotatably connected to a lifting plate, a hydraulic cylinder is fixed between the lifting plate and the dilution cylinder, the top end of the center rod extends out of the top of the sleeve and is fixed to a U-shaped frame, the U-shaped frame is fixed to the top of the lifting plate, and a rotating component matching the sleeve is arranged on the lifting plate.

[0007] Preferably, a fixing plate is fixedly connected to the outer side of the rotating shaft, two fixing plates are provided, and a stirring blade is fixedly connected between the two fixing plates.

[0008] Preferably, the rotating assembly includes a bevel gear 1 coaxially fixed to the outside of the sleeve, a motor fixed to the top of the lifting plate, and a bevel gear 2 coaxially fixed to the output shaft of the motor, and the bevel gear 2 is meshed with the bevel gear 1.

[0009] Preferably, two rotating axes are symmetrically arranged.

[0010] Preferably, the bottom end of the center rod is rotatably connected to the bottom surface of the mechanism housing.

[0011] The beneficial effects of the utility model are as follows: through the setting of the stirring mechanism, the rotating shaft can realize synchronous rotation, revolution, and up and down movement, driving the stirring blades to stir the reagents and accelerate the dilution. While achieving the same stirring effect as the existing stirring mechanism, the gears of the stirring mechanism do not contact the reagents, the surfaces of the sleeve and the mechanism shell are smooth, the reagents are not easy to adhere, and they are easy to clean, which greatly reduces the workload of subsequent cleaning. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 The utility model is a schematic diagram of the overall structure of a reagent antibody diluter.

[0013] Figure 2 The utility model is a schematic diagram of the stirring mechanism structure of a reagent antibody diluter.

[0014] Figure 3 The utility model discloses a half planing diagram of a sleeve and a mechanism shell of a reagent antibody diluter.

[0015] (1. Dilution cylinder; 2. Lifting plate; 3. Motor; 4. U-shaped frame; 5. Bevel gear 1; 6. Casing; 7. Hydraulic cylinder; 8. Bevel gear 2; 9. Center rod; 10. Mechanism housing; 11. Rotating shaft; 12. Fixed plate; 13. Stirring blade; 14. Bevel gear 3; 15. Bevel gear 4) DETAILED DESCRIPTION

[0016] The preferred embodiments of the present utility model will be described in detail below in conjunction with the accompanying drawings.

[0017] Reference Figures 1 to 3 The utility model provides a reagent antibody diluter, comprising a dilution cylinder 1, wherein the dilution cylinder 1 is connected with a stirring mechanism, wherein the stirring mechanism comprises a sleeve 6 penetrating the top of the dilution cylinder 1 and being slidably connected with the dilution cylinder 1, a mechanism shell 10 fixed at the bottom of the sleeve 6, a center rod 9 rotatably arranged on the inner side of the sleeve 6, a bevel gear three 14 fixed at the bottom end of the center rod 9, a rotating shaft 11 rotatably arranged on the side wall of the mechanism shell 10, and a bevel gear four 15 fixed at the end of the rotating shaft 11 and meshing with the bevel gear three 14, wherein the bottom end of the center rod 9 is rotatably connected with the bottom surface of the mechanism shell 10, the bevel gear three 14 and the bevel gear four 15 are both arranged on the inner side of the mechanism shell 10, the top end of the sleeve 6 is rotatably connected with a lifting plate 2, a hydraulic cylinder 7 is fixed between the lifting plate 2 and the dilution cylinder 1, the top end of the center rod 9 extends out of the top of the sleeve 6 and is fixed with a U-shaped frame 4, the U-shaped frame 4 is fixed at the top of the lifting plate 2, and a rotating component matching with the sleeve 6 is arranged on the lifting plate 2. Specifically, the hydraulic cylinder 7 can drive the lifting plate 2 to move up and down. When the lifting plate 2 moves up and down, it drives the sleeve 6, the center rod 9, the mechanism shell 10, and the rotating shaft 11 to move synchronously. Then, the sleeve 6 is driven to rotate through the rotating component, and the sleeve 6 drives the mechanism shell 10 to rotate. The mechanism shell 10 drives the rotating shaft 11 to rotate. Since the center rod 9 is fixed by the U-shaped frame 4, that is, the bevel gear three 14 is fixed, when the rotating shaft 11 rotates, it drives the bevel gear four 15 to rotate circumferentially around the bevel gear three 14. Under the action of the bevel gear three 14, the bevel gear four 15 is rotated, thereby driving the rotating shaft 11 to rotate, achieving the effect that the rotating shaft 11 moves up and down while revolving and rotating synchronously.

[0018] Furthermore, in the utility model, two rotating shafts 11 are symmetrically arranged, and a fixing plate 12 is fixedly connected to the outer side of the rotating shaft 11. Two fixing plates 12 are arranged, and a stirring blade 13 is fixedly connected between the two fixing plates 12. Figure 2 As shown, the fixed plate 12 is a triangular plate, and the stirring blade 13 is twisted in a spiral shape and fixed between the two fixed plates 12. When the rotating shaft 11 rotates, the stirring blade 13 is driven to rotate, so as to stir the reagent and increase the dilution rate.

[0019] Furthermore, the rotating assembly in the utility model includes a bevel gear 1 5 coaxially fixed to the outside of the sleeve 6, a motor 3 fixed to the top of the lifting plate 2, and a bevel gear 2 8 coaxially fixed to the output shaft of the motor 3, and the bevel gear 2 8 is meshed with the bevel gear 1 5. Specifically, the motor 3 can drive the bevel gear 2 8 to rotate, the bevel gear 2 8 drives the bevel gear 1 5 to rotate, and the bevel gear 1 5 drives the sleeve 6 to rotate.

[0020] Working principle: After the antibody and diluent are added to the inside of the dilution cylinder 1, the motor 3 is started to drive the sleeve 6 to rotate, the sleeve 6 drives the mechanism shell 10 to rotate, the mechanism shell 10 drives the rotating shaft 11 to rotate, and the rotating shaft 11 drives the bevel gear 4 15 to rotate around the bevel gear 3 14. The bevel gear 4 15 will rotate on its own, thereby driving the rotating shaft 11 to rotate, and the rotating shaft 11 drives the stirring blade 13 to rotate, stirring the reagent and accelerating the dilution. At the same time, the hydraulic cylinder 7 is started, and the hydraulic cylinder 7 drives the lifting plate 2 to move up and down, and the lifting plate 2 drives the sleeve 6, the center rod 9, the mechanism shell 10, and the rotating shaft 11 to move synchronously, so as to achieve the effect that the rotating shaft 11 moves up and down while rotating. When the reagent is fully stirred and the dilution is accelerated, since the surface of the sleeve 6 and the mechanism shell 10 is smooth, the surface is not easy to adhere to the reagent, and it is also easy to clean after use.

[0021] The above description of the utility model and its implementation methods is not restrictive. The drawings show only one implementation method of the utility model, and the actual structure is not limited thereto. In short, if ordinary technicians in this field are inspired by it and design structural methods and embodiments similar to the technical solution without creativity without departing from the purpose of the invention of the utility model, they should all fall within the protection scope of the utility model.

Claims

1. A reagent antibody diluter, comprising a dilution cylinder, wherein the dilution cylinder is connected to a stirring mechanism, characterized in that: The stirring mechanism includes a sleeve that passes through the top of the dilution cylinder and is slidably connected to the dilution cylinder, a mechanism shell fixed to the bottom of the sleeve, a center rod rotatably arranged on the inner side of the sleeve, a bevel gear three fixed to the bottom end of the center rod, a rotating shaft rotatably arranged on the side wall of the mechanism shell, and a bevel gear four fixed to the end of the rotating shaft and meshing with the bevel gear three. The bevel gear three and the bevel gear four are both arranged on the inner side of the mechanism shell. The top end of the sleeve is rotatably connected to a lifting plate, a hydraulic cylinder is fixed between the lifting plate and the dilution cylinder, the top end of the center rod extends out of the top of the sleeve and is fixed to a U-shaped frame, the U-shaped frame is fixed to the top of the lifting plate, and a rotating component matching the sleeve is provided on the lifting plate.

2. A reagent antibody diluter according to claim 1, characterized in that: A fixing plate is fixedly connected to the outer side of the rotating shaft, two fixing plates are provided, and a stirring blade is fixedly connected between the two fixing plates.

3. A reagent antibody diluter according to claim 1, characterized in that: The rotating assembly includes a bevel gear 1 coaxially fixed to the outside of the sleeve, a motor fixed to the top of the lifting plate, and a bevel gear 2 coaxially fixed to the output shaft of the motor, wherein the bevel gear 2 is meshed with the bevel gear 1.

4. A reagent antibody diluter according to claim 1, characterized in that: Two rotating shafts are symmetrically arranged.

5. A reagent antibody diluter according to claim 1, characterized in that: The bottom end of the center rod is rotatably connected to the bottom surface of the mechanism housing.