Cryopreservation box for hematopoietic stem cell multi-cavity cryopreservation bag

By introducing buffer components and side support into the frozen storage box, the problem of insufficient anti-collision performance of the frozen storage box is solved, and effective protection of the frozen storage bag and safety improvement in transportation is achieved.

CN222137360UInactive Publication Date: 2024-12-10HENAN BEIKE BIOTECHNOLOGY CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202420954868.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-06
Publication Date
2024-12-10
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

The existing frozen storage boxes used for hematopoietic stem cell multi-chamber frozen storage bags have poor anti-collision performance, which can easily lead to the frozen storage bag being squeezed or folded during transportation, and cannot effectively protect the frozen storage bag.

Method used

A frozen storage box is designed, including a buffer assembly and a side support member, which drives the placement assembly to move in horizontal and vertical directions through the buffer assembly, and uses the side support members to provide limiting and extrusion buffering to improve collision resistance. Storing the frozen storage bags independently by placing the components and guardrails is avoided by stacking and squeezing and folding.

Benefits of technology

Effectively improve the buffering effect of the frozen storage box during collision, prevent damage to the frozen storage bag, and avoid extrusion and folding caused by the accumulation of frozen storage bags during transportation through independent storage and impact-resistant materials, ensuring safe storage of the frozen storage bags and transportation.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN222137360U_ABST
    Figure CN222137360U_ABST
Patent Text Reader

Abstract

The utility model discloses a cryopreservation box for a hematopoietic stem cell multi-chamber cryopreservation bag, and relates to the field of medical instruments, the cryopreservation box comprises a box body and a cover plate movably installed on the top of the box body, a buffer assembly is fixedly installed on the bottom surface in the box body, a placing assembly is fixedly installed on the top of the buffer assembly, and the placing assembly is fixedly installed on the bottom surface of the box body. A side supporting piece located on the outer side of the containing assembly is fixedly installed on the inner side of the box body. By arranging the buffering assembly located in the box body and installing the containing assembly on the top of the buffering assembly, when the box body is collided, the buffering assembly drives the containing assembly to move in the horizontal direction and the vertical direction for buffering, and the containing assembly is limited while being matched with extrusion buffering of the side supporting pieces; and therefore, a buffering effect is provided when the box body is collided, the anti-collision performance is improved, and the cryopreservation bag can be protected.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The utility model relates to the field of medical instruments, in particular to a freezing box for a multi-chamber freezing bag of hematopoietic stem cells. Background Art

[0002] Hematopoietic stem cells are adult stem cells in the blood system. They are a heterogeneous group with the ability of long-term self-renewal and the potential to differentiate into various mature blood cells. They are the type of adult stem cells with the longest and most in-depth research history, and have important guiding significance for the study of various stem cells, including tumor stem cells. After the hematopoietic stem cells are extracted, the stem cells are placed in a cryopreservation bag, and then the cryopreservation bag is placed in a cryopreservation box for storage.

[0003] Existing cryopreservation boxes for multi-chamber cryopreservation bags of hematopoietic stem cells have poor anti-collision performance, making it inconvenient to protect the cryopreservation bags. Multiple cryopreservation bags are stacked, and road bumps during transportation may cause multiple cryopreservation bags in the cryopreservation box to be squeezed or folded, which is not conducive to the storage of the cryopreservation bags. Utility Model Content

[0004] In order to solve the above technical problems, the technical solution adopted by the utility model is:

[0005] A freezing box for a multi-chamber freezing bag of hematopoietic stem cells comprises a box body and a cover plate movably mounted on the top of the box body, a buffer component is fixedly mounted on the bottom surface of the box body, a placement component is fixedly mounted on the top of the buffer component, and a side support member located outside the placement component is fixedly mounted on the inner side of the box body.

[0006] A further improvement of the technical solution of the utility model is that: the buffer assembly includes a mounting plate, a sliding groove is opened on the inner side of the mounting plate, a fixed block is fixedly connected to the inside of the sliding groove, a sliding block located on the right side of the fixed block is movably connected to the inside of the sliding groove, a buffer spring is fixedly connected to the inner sides of the fixed block and the sliding block, a movable seat located on the inner side of the buffer spring is movably connected to the inside of the mounting plate, a supporting sleeve is fixedly connected to the top of the supporting sleeve, and a buffer spring is movably installed inside the supporting sleeve.

[0007] A further improvement of the technical solution of the utility model is that the placement component includes a storage frame, a placement slot with a top opening is provided inside the storage frame, a through hole is provided inside the storage frame, and a protective frame is movably connected inside the placement slot.

[0008] A further improvement of the technical solution of the utility model is that: a total of four buffer springs are provided, and the four buffer springs are located outside the movable seat.

[0009] A further improvement of the technical solution of the utility model is that the buffer spring is made of metal.

[0010] A further improvement of the technical solution of the utility model is that: the protection frame includes a frame body and a through opening, the frame body is open at the top, and the through opening is opened on the side of the frame body.

[0011] A further improvement of the technical solution of the utility model is that: the frame is made of polyethylene plastic.

[0012] A further improvement of the technical solution of the utility model is that a side support spring piece is arranged inside the side support member.

[0013] Due to the adoption of the above technical solution, the utility model has achieved the following technical progress compared with the prior art:

[0014] 1. The utility model provides a freezing box for a multi-chamber freezing bag of hematopoietic stem cells. The utility model provides a buffer component located inside the box body, and installs a placement component on the top of the buffer component. When the box body is hit, the buffer component drives the placement component to move horizontally and vertically for buffering. The side support members squeeze and buffer while limiting the placement component, thereby providing a buffering effect when the box body is hit, improving the anti-collision performance, and protecting the freezing bag.

[0015] 2. The utility model provides a cryopreservation box for multi-chamber cryopreservation bags of hematopoietic stem cells. By providing a placement component, the cryopreservation bags are stored independently inside the placement component, and the cryopreservation bags are separated by impact-resistant materials provided in the placement component, thereby avoiding squeezing and folding caused by the stacking of multiple cryopreservation bags during transportation. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic structural diagram of a cryopreservation box for a multi-chamber cryopreservation bag for hematopoietic stem cells according to the utility model;

[0017] Figure 2 It is a schematic diagram of the cross-sectional structure of the utility model;

[0018] Figure 3 It is a structural schematic diagram of the buffer component of the utility model;

[0019] Figure 4 It is a structural schematic diagram of the placement component of the utility model;

[0020] Figure 5 It is a structural schematic diagram of the protection frame of the utility model.

[0021] In the figure: 1. box body; 2. cover plate; 3. buffer assembly; 31. mounting plate; 32. sliding groove; 33. fixing block; 34. sliding block; 35. buffer spring; 36. movable seat; 37. supporting sleeve; 38. buffer spring; 4. placement assembly; 41. storage frame; 42. placement groove; 43. through hole; 44. protection frame; 441. frame body; 442. through opening; 5. side support member. DETAILED DESCRIPTION

[0022] The utility model is further described in detail below:

[0023] like Figures 1 to 5 As shown, the utility model provides a freezing box for a multi-chamber freezing bag of hematopoietic stem cells, comprising a box body 1 and a cover plate 2 movably mounted on the top of the box body 1, a buffer component 3 is fixedly mounted on the bottom surface of the box body 1, a placement component 4 is fixedly mounted on the top of the buffer component 3, and a side support member 5 located on the outside of the placement component 4 is fixedly mounted on the inner side of the box body 1.

[0024] By providing a buffer component 3 located inside the box body 1 and installing the placement component 4 on the top of the buffer component 3, when the box body 1 is hit, the buffer component 3 drives the placement component 4 to move horizontally and vertically for buffering, and the side support member 5 squeezes and buffers while limiting the placement component 4, thereby providing a buffering effect when the box body 1 is hit, improving the anti-collision performance, and protecting the cryobags. At the same time, by providing the placement component 4, the cryobags are stored independently inside the placement component 4, and impact-resistant materials are provided in the placement component 4 to separate the cryobags, thereby avoiding squeezing and folding caused by the stacking of multiple cryobags during transportation.

[0025] like Figure 3 As shown, the buffer assembly 3 includes a mounting plate 31, a sliding groove 32 is provided on the inner side of the mounting plate 31, a fixed block 33 is fixedly connected inside the sliding groove 32, a sliding block 34 located on the right side of the fixed block 33 is movably connected inside the sliding groove 32, a buffer spring 35 is fixedly connected on the inner sides of the fixed block 33 and the sliding block 34, a movable seat 36 located on the inner side of the buffer spring 35 is movably connected inside the mounting plate 31, a supporting sleeve 37 is fixedly connected to the top of the supporting sleeve 37, and a buffer spring 38 is movably installed inside the supporting sleeve 37.

[0026] The movable seat 36 is driven by the placement component 4 to slide in all directions in the installation disk 31. When the movable seat 36 slides toward one side, it squeezes the buffer spring sheet 35 on the corresponding side, so that the buffer spring sheet 35 is forced to push the sliding block 34 to slide outward along the inside of the sliding groove 32, so that the buffer spring sheet 35 is deformed and cooperates with the placement component 4 to squeeze the side support member 5 to deform and absorb energy. The buffer spring sheet 35 and the side support member 5 are elastically deformed and then reset to push the placement component 4 and the movable seat 36 to reset. At the same time, the placement component 4 can press down the support sleeve 37 to compress the buffer spring 38 inside it. The elastic force of the buffer spring 38 buffers the up and down movement of the placement component 4, thereby buffering the collision, improving the anti-collision performance and the protection effect on the cryopreservation bag.

[0027] like Figure 4 As shown, the placement component 4 includes a storage frame 41 , a placement slot 42 with a top opening is provided inside the storage frame 41 , a through hole 43 is provided inside the storage frame 41 , and a protective frame 44 is movably connected inside the placement slot 42 .

[0028] By placing the hematopoietic stem cell cryopreservation bag on the inner side of the protective frame 44 and by clamping the protective frame 44 in the placement slot 42, the placement slots 42 are separated to prevent multiple cryopreservation bags from being piled up and squeezed and folded, thereby facilitating the storage and transportation of the cryopreservation bags.

[0029] like Figure 3 As shown, there are four buffer springs 35 in total, and the four buffer springs 35 are arranged outside the movable seat 36 .

[0030] The buffer spring 35 is made of metal.

[0031] The four buffer springs 35 are located outside the movable seat 36, and the movable seat 36 movably squeezes the buffer springs 35 to provide buffering, thereby improving the anti-collision performance and the protection effect on the cryopreservation bag.

[0032] like Figure 5 As shown, the protection frame 44 includes a frame body 441 and a through opening 442 . The frame body 441 is open at the top, and the through opening 442 is opened on the side of the frame body 441 .

[0033] The frame 441 is made of polyethylene plastic.

[0034] The through opening 442 opened on the side of the frame 441 cooperates with the through hole 43 to ensure gas circulation to maintain the low temperature of the cryopreservation bag. At the same time, the frame 441 is made of polyethylene plastic material with good impact resistance, toughness and chemical corrosion resistance, thereby ensuring the protective effect.

[0035] like Figure 2 As shown, a side supporting spring piece is arranged inside the side supporting member 5 .

[0036] When the placement component 4 moves, the side support member 5 is squeezed and deformed to provide a buffer and push the placement component 4 to return to its original position.

[0037] The working principle of the cryopreservation box of the multi-chamber cryopreservation bag for hematopoietic stem cells will be described in detail below.

[0038] like Figures 1 to 5 As shown, by placing the frame 441 in the placement groove 42, and placing the hematopoietic stem cell freezing bag on the inner side of the frame 441, the placement grooves 42 separated by the storage frame 41 prevent multiple freezing bags from being piled up and squeezed and folded, and the frame 441 is made of rubber material to prevent scratches on the freezing bags. At the same time, during transportation, the storage frame 41 moves along the inside of the box body 1 to squeeze the side support member 5 and drive the movable seat 36 to slide in all directions in the installation plate 31, and the movable seat 36 slides toward one side. When the movable seat 36 is moved, the buffer spring piece 35 on the corresponding side is squeezed, so that the buffer spring piece 35 is forced to push the sliding block 34 to slide outward along the inside of the sliding groove 32, so that the buffer spring piece 35 is deformed and cooperates with the protective frame 44 to squeeze the side support member 5 to deform and absorb energy. The buffer spring piece 35 and the side support member 5 are elastically deformed and then reset to push the protective frame 44 and the movable seat 36 to reset. At the same time, the protective frame 44 can press down the support sleeve 37 to compress the buffer spring 38 inside it. The elastic force of the buffer spring 38 buffers the up and down movement of the protective frame 44, thereby buffering the collision.

[0039] The above generally describes the present invention in detail, but it is obvious to a person skilled in the art that some modifications or improvements can be made to the present invention. Therefore, modifications or improvements that do not deviate from the spirit of the present invention are within the scope of protection of the present invention.

Claims

1. A cryopreservation box for a multi-chamber cryopreservation bag for hematopoietic stem cells, comprising a box body (1) and a cover plate (2) movably mounted on the top of the box body (1), characterized in that: A buffer component (3) is fixedly mounted on the bottom surface of the box body (1), a placement component (4) is fixedly mounted on the top of the buffer component (3), and a side support component (5) located outside the placement component (4) is fixedly mounted on the inner side of the box body (1).

2. A cryopreservation box for a multi-chamber cryopreservation bag for hematopoietic stem cells according to claim 1, characterized in that: The buffer assembly (3) comprises a mounting plate (31), a sliding groove (32) is provided on the inner side of the mounting plate (31), a fixed block (33) is fixedly connected to the inside of the sliding groove (32), a sliding block (34) located on the right side of the fixed block (33) is movably connected to the inside of the sliding groove (32), a buffer spring (35) is fixedly connected to the inner sides of the fixed block (33) and the sliding block (34), a movable seat (36) located on the inner side of the buffer spring (35) is movably connected to the inside of the mounting plate (31), a supporting sleeve (37) is fixedly connected to the top of the movable seat (36), and a buffer spring (38) is movably installed inside the supporting sleeve (37).

3. A cryopreservation box for a multi-chamber cryopreservation bag for hematopoietic stem cells according to claim 2, characterized in that: The placement assembly (4) comprises a storage frame (41), a placement slot (42) with a top opening is provided inside the storage frame (41), a through hole (43) is provided inside the storage frame (41), and a protective frame (44) is movably connected inside the placement slot (42).

4. A cryopreservation box for a multi-chamber cryopreservation bag for hematopoietic stem cells according to claim 2, characterized in that: A total of four buffer spring sheets (35) are provided, and the four buffer spring sheets (35) are arranged outside the movable seat (36).

5. The cryopreservation box of the multi-chamber cryopreservation bag for hematopoietic stem cells according to claim 2, characterized in that: The buffer spring (35) is made of metal.

6. The cryopreservation box of the multi-chamber cryopreservation bag for hematopoietic stem cells according to claim 3, characterized in that: The protection frame (44) comprises a frame body (441) and a through opening (442); the frame body (441) is open at the top, and the through opening (442) is opened on the side of the frame body (441).

7. A cryopreservation box for a multi-chamber cryopreservation bag for hematopoietic stem cells according to claim 6, characterized in that: The frame (441) is made of polyethylene plastic.

8. The cryopreservation box of the multi-chamber cryopreservation bag for hematopoietic stem cells according to claim 1, characterized in that: A side supporting spring sheet is arranged inside the side supporting member (5).