Saliva DNA extraction kit based on paramagnetic particle method

By designing a magnetic bead saliva DNA extraction kit with threaded connection and deformation clamp pad, the problem of easy damage and inconvenient cleaning of the test tube during handling is solved, the test tube is quickly fixed and conveniently cleaned, and the safety of the test tube is improved. and maintenance efficiency.

CN222180226UActive Publication Date: 2024-12-17SIRIUS BIOTECHNOLOGY (JILIN) CO LTD
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Patent Information

Application Number
CN202322817462.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2023-10-19
Publication Date
2024-12-17
Estimated Expiration
2033-10-19

AI Technical Summary

Technical Problem

The existing magnetic bead saliva DNA extraction kit is prone to damage to the test tube due to handling when storing the test tube, and it is inconvenient to clean after breaking.

Method used

A reagent kit including a box body, a box cover, a hollow column and a clamp pad is designed to achieve the fixing and rapid disassembly of the test tube through threaded connection and deformed clamp pad, making it easy to clean.

Benefits of technology

It realizes rapid fixation and storage of test tubes, and is conveniently cleaned after the test tubes rupture, avoiding the accumulation of contamination in the kit.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a paramagnetic particle method saliva DNA (deoxyribonucleic acid) extraction kit, which comprises a kit body and a kit cover, an internal space is arranged in the kit body, a plurality of threaded holes are arranged on the bottom wall of the internal space, connecting columns are in threaded connection with the interiors of the threaded holes, hollow columns for placing reagent tubes are fixedly connected with the upper ends of the connecting columns, and the lower ends of the hollow columns are fixedly connected with the kit cover. A fixing mechanism for fixing a reagent tube is arranged in the hollow column, the fixing mechanism comprises four clamping grooves formed in the inner wall of the hollow column, clamping strips are inserted into the clamping grooves, a test tube can be rapidly fixed and stored through a first clamping pad and a second clamping pad, and when the test tube is accidentally broken, the clamping strips are inserted into the clamping grooves. The hollow column can be taken out, and the first clamping pad and the second clamping pad can be detached, so that the broken polluted part can be conveniently cleaned.
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Description

Technical Field

[0001] The utility model relates to the field of test kits, in particular to a test kit for extracting saliva DNA using a magnetic bead method. Background Art

[0002] In the prior art, the magnetic bead method saliva DNA extraction kit needs to be frequently carried when storing the test tube, but the test tube cannot be fixed in the kit, so the test tube is constantly shaken during the transportation process, which is very likely to cause the test tube storing the reagent to be damaged. After the test tube is damaged, it is inconvenient to clean the kit because the test tube placement hole for placing the test tube is integrated with the kit.

[0003] Based on this, the utility model proposes a magnetic bead method saliva DNA extraction kit which can fix a test tube and can be easily cleaned after the test tube is accidentally broken. Utility Model Content

[0004] In order to overcome the defects in the above-mentioned prior art, the utility model provides a magnetic bead method saliva DNA extraction kit, which can realize rapid fixation and storage of the test tube through the first clamping pad and the second clamping pad, and when the test tube is accidentally broken, the hollow column can be taken out and the first clamping pad and the second clamping pad can be removed, thereby realizing convenient cleaning of the broken and contaminated areas.

[0005] Technical Solution

[0006] A magnetic bead method saliva DNA extraction kit comprises a box body and a box cover, wherein an internal space is arranged in the box body, a plurality of threaded holes are arranged on the bottom wall of the internal space, a connecting column is threadedly connected in the threaded hole, a hollow column for placing a reagent tube is fixedly connected to the upper end of the connecting column, and a fixing mechanism for fixing the reagent tube is arranged in the hollow column.

[0007] Furthermore, the fixing mechanism includes four slots arranged inside the inner wall of the hollow column, and the slots are inserted with clamping strips.

[0008] Furthermore, a first clamping pad and a second clamping pad are fixedly disposed on the two opposite clamping strips respectively.

[0009] Furthermore, a bottom pad is provided on the inner bottom wall of the hollow column.

[0010] Furthermore, the first clamping pad and the second clamping pad are capable of deformation.

[0011] Furthermore, a circular channel is provided between the first clamping pad and the second clamping pad.

[0012] Furthermore, the diameter of the circular channel is smaller than the diameter of the reagent tube.

[0013] Furthermore, a low resistance layer is provided on the annular side wall of the first clamping pad and the second clamping pad that constitute the circular channel.

[0014] Beneficial Effects

[0015] Compared with the prior art, the utility model has the following beneficial effects: the test tube can be quickly fixed and stored by the first clamping pad and the second clamping pad, and when the test tube is accidentally broken, the hollow column can be taken out and the first clamping pad and the second clamping pad can be removed, thereby realizing convenient cleaning of the broken and contaminated parts. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a schematic diagram of the structure of a magnetic bead-based saliva DNA extraction kit of the utility model;

[0017] Figure 2 for Figure 1 Schematic diagram of the structure in the AA direction.

[0018] Reference Numbers

[0019] Fixing mechanism 900 , box cover 1 , first clamping pad 2 , clamping strip 3 , internal space 4 , connecting column 5 , hollow column 6 , threaded hole 7 , box body 8 , second clamping pad 9 , clamping groove 10 , circular channel 11 , bottom pad 12 . DETAILED DESCRIPTION

[0020] In order to better illustrate the content of the utility model, the following is a description with reference to the accompanying drawings and implementation examples:

[0021] have Figure 1-Figure 2 As shown, the utility model discloses a magnetic bead method saliva DNA extraction kit, comprising a box body 8 and a box cover 1, wherein the box body 8 is provided with an internal space 4, a plurality of threaded holes 7 are provided on the bottom wall of the internal space 4, a connecting column 5 is threadedly connected to the threaded hole 7, a hollow column 6 for placing a reagent tube is fixedly connected to the upper end of the connecting column 5, and a fixing mechanism 900 for fixing the reagent tube is provided in the hollow column 6.

[0022] Furthermore, the fixing mechanism 900 includes four slots 10 disposed inside the inner wall of the hollow column 6 , and the clips 3 are inserted into the slots 10 .

[0023] Furthermore, a first clamping pad 2 and a second clamping pad 9 are fixedly disposed on the two opposite clamping strips 3 respectively.

[0024] Furthermore, a bottom pad 12 is provided on the inner bottom wall of the hollow column 6 .

[0025] Furthermore, the first clamping pad 2 and the second clamping pad 9 are capable of deformation.

[0026] Furthermore, a circular channel 11 is provided between the first clamping pad 2 and the second clamping pad 9 .

[0027] Furthermore, the diameter of the circular channel 11 is smaller than the diameter of the reagent tube.

[0028] Furthermore, a low resistance layer (not shown) is provided on the annular side wall of the first clamping pad 2 and the second clamping pad 9 that constitutes the circular channel 11 .

[0029] Specifically, when in use, the box cover 1 is opened, and the reagent tube is inserted into the circular channel 11 until the bottom of the reagent tube contacts the bottom pad 12. At this time, the first clamping pad 2 and the second clamping pad 9 are squeezed and deformed by the reagent tube and squeezed toward the reagent tube to clamp the reagent tube;

[0030] When the reagent tube breaks accidentally, directly rotate the hollow column 6 to screw the connecting column 5 out of the threaded hole. Then take out the hollow column 6, pull out the card strip 3, take out the first clamping pad 2 and the second clamping pad 9, and then clean the inside of the hollow column 6.

[0031] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model, rather than to limit it. Although the technical solution of the utility model has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solution recorded in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solution from the spirit and scope of the technical solution of each embodiment of the utility model.

Claims

1. A magnetic bead method saliva DNA extraction kit, characterized in that: The invention comprises a box body (8) and a box cover (1), wherein an internal space (4) is arranged in the box body (8), a plurality of threaded holes (7) are arranged on the bottom wall of the internal space (4), a connecting column (5) is threadedly connected to the threaded hole (7), a hollow column (6) for placing a reagent tube is fixedly connected to the upper end of the connecting column (5), and a fixing mechanism (900) for fixing the reagent tube is arranged in the hollow column (6); The fixing mechanism (900) comprises four card slots (10) arranged inside the inner wall of the hollow column (6), and the card strips (3) are inserted into the card slots (10); A first clamping pad (2) and a second clamping pad (9) are fixedly arranged on the two opposite clamping strips (3) respectively; The first clamping pad (2) and the second clamping pad (9) are capable of deformation; A circular channel (11) is provided between the first clamping pad (2) and the second clamping pad (9).

2. A magnetic bead method saliva DNA extraction kit according to claim 1, characterized in that: A bottom pad (12) is provided on the inner bottom wall of the hollow column (6).

3. A magnetic bead method saliva DNA extraction kit according to claim 2, characterized in that: The diameter of the circular channel (11) is smaller than the diameter of the reagent tube.

4. A magnetic bead method saliva DNA extraction kit according to claim 3, characterized in that: A low resistance layer is provided on the annular side wall of the first clamping pad (2) and the second clamping pad (9) forming the circular channel (11).