Diagnostic kit based on gastric cancer molecule sequencing

Abstract

The utility model discloses a diagnostic kit based on stomach cancer molecule sequencing, which relates to the technical field of kits and comprises a kit body, the top end of the kit body is rotatably connected with a top cover, a fixed magnetic sheet is embedded in the center of the bottom end of the top cover, a positioning plate is slidably arranged in the kit body, a channel is arranged in the center of the top end of the positioning plate, and the top end of the positioning plate is provided with a magnetic sheet. A plurality of sets of positioning holes are formed in the top end of the positioning plate and located on the outer side of the channel in an annular array mode, and a pressurizing assembly fixed to the inner wall of the bottom end of the box body is arranged in the channel. The reagent tubes are distributed in an annular array shape through the positioning plate, samples stored in the reagent tubes are clearly known in cooperation with the marking frame, the manual taking and placing effect is high, meanwhile, when the top cover is closed, the pressurizing assembly is matched to extrude the outer walls of the placed reagent tubes, the condition that the reagent tubes are damaged due to shaking is avoided, and the reagent tubes are convenient to use. The protection performance of the kit on the reagent tube is better.

Description

Technical Field

[0001] The utility model relates to the technical field of kits, in particular to a diagnostic kit based on gastric cancer molecular sequencing. Background Art

[0002] Gastric cancer is a common cancer, and its incidence ranks first among various malignant tumors in my country. Many gastric cancer patients are often in the middle or late stages when they seek medical treatment. For advanced gastric cancer, the gastric cancer molecular sequencing diagnostic kit using NGS sequencing technology can help identify potential gene mutations in advanced gastric cancer tissues, thereby guiding targeted medication for patients with advanced gastric cancer.

[0003] An existing patent (authorization announcement number: CN 211167893 U) discloses a gastric cancer molecular sequencing diagnostic kit based on NGS sequencing technology, which is convenient for placing the test tube tray by setting a test tube tray storage cavity, setting a slide groove, a slider and a screw rod to press and fix the test tube tray for easy transportation, setting a soft cushion to prevent the test tube and the inner top wall of the test tube tray storage cavity from being squeezed and damaged, setting a groove to facilitate the clamping and fixing of the cardboard, and setting a sponge to facilitate the compression and shock absorption of the reagent bottle after closing the lid.

[0004] However, the above technical solution still has certain defects. In actual use, different test tubes are needed, and the test tube storage holes opened in the cardboard cannot be installed and placed according to different test tubes, which makes it easy for the test tubes to be unable to be placed, affecting the use of the gastric cancer molecular sequencing diagnostic kit. At the same time, the cardboard test tube storage holes are larger, while the test tubes are smaller. When the test tubes are placed in the larger holes, they will collide with the inner walls of the holes when shaken, thereby causing the test tubes to be damaged or broken. Therefore, a gastric cancer molecular sequencing diagnostic kit is proposed. Utility Model Content

[0005] Based on this, the purpose of the utility model is to provide a diagnostic kit based on gastric cancer molecular sequencing to solve the technical problems raised in the above background.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a diagnostic kit based on gastric cancer molecular sequencing, comprising a box body, the top of the box body is rotatably connected to a top cover, a fixed magnetic sheet is embedded in the center of the bottom end of the top cover, a positioning plate is slidably provided in the box body, a channel is provided at the center of the top end of the positioning plate, the top end of the positioning plate is located outside the channel and has multiple groups of positioning holes in a circular array, and a booster component fixed to the inner wall of the bottom end of the box body is provided in the channel;

[0007] The boost assembly includes a boost cylinder fixed to the inner wall of the bottom end of the box body, a piston is slidably provided in the boost cylinder, a boost rod extending into the channel is provided at the top end of the piston, a moving magnetic sheet is provided at the top end of the boost rod located in the channel, a plurality of groups of arc-shaped frames fixed to the inner wall of the bottom end of the box body are provided on the outside of the boost cylinder, a plurality of groups of airbag strips are provided on the curved inner wall of the arc-shaped frames, a constraint cylinder fixed to the inner wall of the bottom end of the box body is provided on the outside of the plurality of arc-shaped frames, and a rubber ring is pasted on the inner wall of the constraint cylinder.

[0008] As an optimal technical solution of the gastric cancer molecular sequencing diagnostic kit of the utility model, the front end of the top cover is located on the front surface of the box body and is rotatably connected to a constraint plate, the outer wall of the constraint plate is provided with a handle that penetrates the constraint plate, the end of the handle extends to the front surface of the box body and is provided with a positioning plate, a blind hole is provided at the contact position between the front surface of the box body and the positioning plate, two groups of spring beads are provided on the inner wall of the blind hole, and a groove is provided at the contact position between the curved outer wall of the positioning plate and the spring beads.

[0009] As an optimal technical solution of the gastric cancer molecular sequencing diagnostic kit of the utility model, each group of positioning holes is provided with a marking frame on one side close to the channel, and the marking frames are distributed in a circular array on the top of the positioning plate and the number is equal to the positioning holes.

[0010] As an optimal technical solution of the gastric cancer molecular sequencing diagnostic kit of the utility model, the outer wall of the booster rod is located in the channel and is sleeved with a return spring, and the two ends of the return spring are respectively fixed to the inner wall of the channel and the outer wall of the booster rod.

[0011] As a preferred technical solution of the gastric cancer molecular sequencing diagnostic kit of the utility model, a plurality of groups of air tubes are provided in the box body below the booster cylinder, and the two ends of each group of air tubes connect the arc frame and the booster cylinder.

[0012] As a preferred technical solution of the gastric cancer molecular sequencing diagnostic kit of the utility model, the four inner corners in the box body are fixed with force-bearing pieces, and the top of the force-bearing piece is in contact with the bottom of the positioning plate.

[0013] As a preferred technical solution of the gastric cancer molecular sequencing diagnostic kit of the utility model, the fixed magnetic sheet and the moving magnetic sheet are magnets of the same polarity.

[0014] In summary, the utility model mainly has the following beneficial effects:

[0015] The utility model arranges the reagent tubes in a circular array through the positioning plate, and cooperates with the marking frame to clearly understand the samples stored in the reagent tubes, so that the manual taking and placing is efficient. At the same time, when the top cover is closed, the booster component produces a squeezing effect on the outer wall of the inserted reagent tube, avoiding the reagent tube from shaking and being damaged, so that the reagent test kit has better protection performance for the reagent tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a three-dimensional diagram of the utility model;

[0017] Figure 2 It is a perspective unfolded view of the utility model;

[0018] Figure 3 It is a top view of the box body of the utility model;

[0019] Figure 4 It is a front cutaway view of the box body of the utility model;

[0020] Figure 5 This is a diagram of the arc-shaped frame structure of the utility model;

[0021] Figure 6 This is a front structural diagram of the box body of the utility model;

[0022] Figure 7 This is a structural diagram of the positioning piece and handle of the utility model.

[0023] In the figure: 100, box body; 101, force-bearing sheet; 102, blind hole; 103, spring bead;

[0024] 110, top cover; 111, restraining plate; 112, fixed magnetic sheet; 113, positioning sheet; 114, handle;

[0025] 120. Positioning plate; 121. Positioning hole; 122. Marking frame; 123. Channel; 124. Constraint cylinder; 130. Arc-shaped frame; 131. Airbag strip; 140. Boosting assembly; 141. Boosting cylinder; 142. Piston; 143. Moving magnetic sheet; 144. Boosting rod; 145. Air pipe. DETAILED DESCRIPTION

[0026] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. The embodiments described below with reference to the drawings are exemplary and are only used to explain the utility model, and cannot be understood as limiting the utility model.

[0027] The following describes an embodiment of the utility model based on its overall structure.

[0028] A diagnostic kit based on gastric cancer molecular sequencing, such as Figures 1 to 7 As shown, it includes a box body 100, the top of the box body 100 is rotatably connected to a top cover 110, a fixed magnetic sheet 112 is embedded in the center of the bottom end of the top cover 110, a positioning plate 120 is slidably arranged in the box body 100, a channel 123 is opened at the center of the top end of the positioning plate 120, the top end of the positioning plate 120 is located outside the channel 123 and is provided with a plurality of groups of positioning holes 121 in a circular array, and a booster assembly 140 fixed to the inner wall of the bottom end of the box body 100 is arranged in the channel 123;

[0029] The booster assembly 140 includes a booster cylinder 141 fixed to the inner wall of the bottom end of the box body 100, a piston 142 is slidably arranged in the booster cylinder 141, a booster rod 144 extending into the channel 123 is arranged at the top end of the piston 142, a moving magnetic sheet 143 is arranged at the top end of the booster rod 144 located in the channel 123, a plurality of groups of arc-shaped frames 130 fixed to the inner wall of the bottom end of the box body 100 are arranged on the outer side of the booster cylinder 141, a plurality of groups of airbag strips 131 are arranged on the curved inner wall of the arc-shaped frames 130, a constraint cylinder 124 fixed to the inner wall of the bottom end of the box body 100 is arranged on the outer side of the plurality of groups of arc-shaped frames 130, and a rubber ring is pasted on the inner wall of the constraint cylinder 124;

[0030] A plurality of air pipes 145 are provided below the booster cylinder 141 in the box body 100, and the two ends of each air pipe 145 connect the arc frame 130 and the booster cylinder 141;

[0031] A marking frame 122 is disposed on one side of each group of positioning holes 121 close to the channel 123 . The marking frames 122 are distributed in a circular array at the top of the positioning plate 120 and the number of the marking frames 122 is equal to the positioning holes 121 .

[0032] The reference mark frame 122 is used to insert the corresponding reagent tube into the positioning hole 121 from top to bottom, so as to facilitate the subsequent manual and efficient removal of the required reagent tube, providing convenience for subsequent work, and at the same time, the top cover 110 and the restraining plate 111 can be closed;

[0033] When the lower surface of the top cover 110 contacts the top of the box body 100, the fixed magnetic piece 112 and the moving magnetic piece 143 are close to each other and generate a repulsive force, so that the moving magnetic piece 143 is lowered linearly along the strip channel 123, and the piston 142 is pushed downward in the booster cylinder 141 through the booster rod 144, so that the air in the booster cylinder 141 enters the arc frame 130 through the air pipe 145, and finally enters the airbag strip 131. The airbag strip 131 expands and contacts the curved outer wall of the reagent tube, and at the same time generates a force pushing the reagent tube to one side, cooperating with the restraint cylinder 124 on the outside, and finally completing the effect of squeezing and fixing the reagent tube, thereby preventing the small diameter reagent tube from sliding in the positioning hole 121, and further improving the protection effect of the reagent tube.

[0034] Please refer to Figure 1 , Figure 6 and Figure 7 The front end of the top cover 110 is located on the front surface of the box body 100 and is rotatably connected to a constraint plate 111. The outer wall of the constraint plate 111 is provided with a handle 114 that penetrates the constraint plate 111. The end of the handle 114 extends to the front surface of the box body 100 and is provided with a positioning piece 113. A blind hole 102 is provided at the contact position between the front surface of the box body 100 and the positioning piece 113. Two groups of spring beads 103 are provided on the inner wall of the blind hole 102. A groove is provided at the contact position between the curved outer wall of the positioning piece 113 and the spring beads 103.

[0035] When closing the top cover 110, the constraint plate 111 is fitted against the front surface of the box body 100, and at the same time, an external force is applied to the handle 114 to make the positioning piece 113 at the end enter the blind hole 102, and at the same time, the spring bead is squeezed to shrink until the positioning piece completely enters the blind hole 102, and the spring bead 103 is reset and enters the groove formed on the curved outer wall of the positioning piece 113, thereby completing the constraint purpose and making the top cover 110 fit against the top of the box body 100. Conversely, applying a pulling force to the handle 114 can achieve the purpose of unlocking, and the constraint plate 111 and the top cover 110 can be rotated to open the box body 100 to carry out the process of taking in and placing the reagent tubes.

[0036] Please refer to Figure 4 The outer wall of the boost rod 144 is located in the channel 123 and is sleeved with a return spring. The two ends of the return spring are respectively fixed to the inner wall of the channel 123 and the outer wall of the boost rod 144.

[0037] The lowered booster rod 144 generates a restoring force, so that it can automatically rise upward, and finally contact the reagent tube to squeeze it, so as to facilitate the direct removal of the reagent tube when the top cover 110 is manually opened.

[0038] Please refer to Figure 3 The four inner corners in the box body 100 are all fixed with force-bearing pieces 101 , and the top of the force-bearing piece 101 contacts the bottom of the positioning plate 120 .

[0039] The purpose of supporting the positioning plate 120 is to prevent the downward movement caused by manual hand touch, thereby ensuring a better storage effect for the reagent tubes.

[0040] Please refer to Figure 2 , the fixed magnetic piece 112 and the moving magnetic piece 143 are magnets of the same pole.

[0041] By utilizing the repulsive force generated between magnets of the same polarity, the moving magnetic sheet 143 is driven downward to achieve the purpose of squeezing the reagent tube.

[0042] When in use, the parts not involved in the device are the same as those in the prior art or can be implemented using the prior art.

[0043] Although an embodiment of the utility model has been shown and described, this specific embodiment is merely an explanation of the utility model and is not a limitation of the utility model. The specific features, structures, materials or characteristics described may be combined in a suitable manner in any one or more embodiments or examples. After reading this specification, those skilled in the art may make modifications, substitutions and variations to the embodiments without creative contributions as needed without departing from the principles and purpose of the utility model. However, as long as they are within the scope of the claims of the utility model, they are protected by patent law.

Claims

1. A gastric cancer molecular sequencing diagnostic kit, comprising a box body (100), Features: The top end of the box body (100) is rotatably connected to a top cover (110), a fixed magnetic sheet (112) is embedded in the center of the bottom end of the top cover (110), a positioning plate (120) is slidably arranged in the box body (100), a channel (123) is provided at the center of the top end of the positioning plate (120), a top end of the positioning plate (120) is located outside the channel (123) and has a plurality of groups of positioning holes (121) in a circular array, and a booster assembly (140) is provided in the channel (123) and is fixed to the inner wall of the bottom end of the box body (100); The boost component (140) includes a boost cylinder (141) fixed to the inner wall of the bottom end of the box body (100), a piston (142) is slidably arranged in the boost cylinder (141), a boost rod (144) extending into the channel (123) is arranged at the top end of the piston (142), a moving magnetic sheet (143) is arranged at the top end of the boost rod (144) located in the channel (123), a plurality of groups of arc-shaped frames (130) fixed to the inner wall of the bottom end of the box body (100) are arranged on the outer side of the boost cylinder (141), a plurality of groups of airbag strips (131) are arranged on the curved inner wall of the arc-shaped frames (130), a restraining cylinder (124) fixed to the inner wall of the bottom end of the box body (100) is arranged on the outer side of the plurality of groups of the arc-shaped frames (130), and a rubber ring is pasted on the inner wall of the restraining cylinder (124).

2. A gastric cancer molecular sequencing diagnostic kit according to claim 1, Features: The front end of the top cover (110) is located on the front surface of the box body (100) and is rotatably connected to a restraining plate (111); the outer wall of the restraining plate (111) is provided with a handle (114) penetrating the restraining plate (111); the end of the handle (114) extends to the front surface of the box body (100) and is provided with a positioning piece (113); a blind hole (102) is provided at a position where the front surface of the box body (100) contacts the positioning piece (113); two groups of spring beads (103) are provided on the inner wall of the blind hole (102); and a groove is provided at a position where the curved outer wall of the positioning piece (113) contacts the spring beads (103).

3. A gastric cancer molecular sequencing diagnostic kit according to claim 1, Features: A marking frame (122) is provided on one side of each group of the positioning holes (121) close to the channel (123). The marking frames (122) are distributed in a circular array at the top of the positioning plate (120) and the number of the marking frames (122) is equal to the positioning holes (121).

4. A gastric cancer molecular sequencing diagnostic kit according to claim 1, Features: The outer wall of the boosting rod (144) is located in the channel (123) and is sleeved with a return spring, and two ends of the return spring are respectively fixed to the inner wall of the channel (123) and the outer wall of the boosting rod (144).

5. A gastric cancer molecular sequencing diagnostic kit according to claim 1, Features: A plurality of groups of air pipes (145) are provided in the box body (100) below the boost cylinder (141), and the two ends of each group of air pipes (145) connect the arc-shaped frame (130) and the boost cylinder (141).

6. A gastric cancer molecular sequencing diagnostic kit according to claim 1, Features: The four inner corners in the box body (100) are all fixed with force-bearing sheets (101), and the top end of the force-bearing sheet (101) is in contact with the bottom end of the positioning plate (120).

7. A gastric cancer molecular sequencing diagnostic kit according to claim 1, Features: The fixed magnetic piece (112) and the moving magnetic piece (143) are magnets of the same polarity.

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