Protein purification column supporting mechanism
By designing a support mechanism for the protein purification column, and utilizing a combination of arc-shaped clamps and fixing pins, the stability and convenience issues of the protein purification column during use were solved, achieving efficient clamping and convenient removal.
Patent Information
- Application Number
- CN202420832584.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-22
- Publication Date
- 2024-12-20
- Estimated Expiration
- 2034-04-22
AI Technical Summary
Protein purification columns suffer from insufficient stability and low convenience during use, especially in terms of placement and removal.
A protein purification column support mechanism was designed, including an installation frame, a placement cavity, a placement plate, a support groove, an arc-shaped clamp, and a fixing pin. The protein purification column is clamped and fixed by the arc-shaped clamp, and the limiting groove and fixing pin are used to achieve stable and convenient removal.
It improves the stability of protein purification columns during use and greatly enhances the ease of placement and removal, making it highly practical.
Smart Images

Figure CN222195994U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of protein purification, in particular to a protein purification column supporting mechanism. Background Art
[0002] Protein separation and purification is an important technique used extensively in biochemical research applications. A typical eukaryotic cell can contain thousands of different proteins, some of which are very abundant and some of which contain only a few copies. In order to study a particular protein, it must first be purified from other proteins and non-protein molecules. Protein purification columns are used in the process of protein purification.
[0003] A support frame is required during the use of a protein purification column. Since it is necessary to ensure the stability of the protein purification column during use and to facilitate its removal later, and considering that the protein purification column is not convenient during placement and later removal, and is not stable enough during use, we proposed a protein purification column support mechanism to solve the above problems. Utility Model Content
[0004] The purpose of the utility model is to provide a protein purification column supporting mechanism to solve the problems raised in the above background technology.
[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a protein purification column support mechanism, comprising an installation frame and a placement cavity, a placement cavity is opened inside the installation frame, a placement plate is installed at the bottom of the inner cavity of the placement cavity, bearing grooves are evenly opened on the top surface of the placement plate, sliding cavities are opened on the inner cavity walls on both sides of the placement cavity, a connecting groove is opened on the surface of the sliding cavity, a limiting sliding groove is opened inside the connecting groove, connecting plates are symmetrically arranged on both sides of the placement cavity, a plurality of arc-shaped clamping plates are evenly arranged on the front of the connecting plate, a fixing plate is connected to the middle of the back of the connecting plate, a handle is connected to the top of the surface of the fixing plate, and fixing pins are slidably sleeved on the outer walls on both sides of the installation frame.
[0006] Preferably, the inner side wall of the sliding cavity is inclined, and the connecting groove and the limiting sliding groove are opened along the inclined surface.
[0007] Preferably, a connecting block is connected to the back side of the connecting plate, one end of the connecting block passes through the connecting groove and is connected to a limiting slider inside the limiting slide groove, and the limiting slider is slidably connected with the limiting slide groove.
[0008] Preferably, the position of the arc-shaped clamping plate corresponds to the position of the bearing groove.
[0009] Preferably, fixing holes are evenly arranged on the back side of the fixing plate, and the fixing pins are plugged into and fixedly connected with the fixing holes.
[0010] Compared with the prior art, the beneficial effects of the utility model are as follows: the utility model first places the required protein purification columns into all the bearing slots respectively, and then drives the connecting plate to move downward along the limiting slide slot through the handle, so that the arc-shaped clamping plate on the connecting plate clamps the protein purification column firmly, and fixes the position of the connecting plate through the fixing pin. When the protein purification column needs to be taken out, it is only necessary to pull out the fixing pin, adjust the handle, move the connecting plate along the limiting slide slot, and keep the arc-shaped clamping plate away from the protein purification column. Compared with the prior art, the protein purification column is inconvenient in placement and later removal, and is not stable enough during use. The method proposed in the utility model clamps the protein purification column firmly through all the arc-shaped clamping plates, and is also extremely convenient to take out the protein purification column, which has high practicality. BRIEF DESCRIPTION OF THE DRAWINGS
[0011] Figure 1 It is a schematic diagram of the overall structure of the utility model.
[0012] In the figure: 1. Installation frame; 2. Placement cavity; 3. Sliding cavity; 4. Connection groove; 5. Limit slide groove; 6. Connection plate; 7. Limit slider; 8. Connection block; 9. Fixed plate; 10. Handle; 11. Arc clamping plate; 12. Placement plate; 13. Load-bearing groove; 14. Fixed pin; 15. Fixed socket. DETAILED DESCRIPTION
[0013] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0014] In the description of the present invention, it should be noted that the terms "vertical", "up", "down", "horizontal", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.
[0015] In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0016] See also Figure 1 The utility model provides a technical solution: a protein purification column support mechanism, including an installation frame 1 and a placement cavity 2, a placement cavity 2 is opened inside the installation frame 1, a placement plate 12 is installed at the bottom of the inner cavity of the placement cavity 2, and a bearing groove 13 is evenly opened on the top surface of the placement plate 12, sliding cavities 3 are opened on the inner cavity walls on both sides of the placement cavity 2, a connecting groove 4 is opened on the surface of the sliding cavity 3, and a limited position sliding groove 5 is opened inside the connecting groove 4, connecting plates 6 are symmetrically arranged on both sides of the placement cavity 2, and a plurality of arc-shaped clamping plates 11 are evenly arranged on the front of the connecting plate 6, a fixing plate 9 is connected to the middle of the back of the connecting plate 6, and a handle 10 is connected to the top of the surface of the fixing plate 9, and fixing pins 14 are slidably sleeved on the outer walls on both sides of the installation frame 1.
[0017] Furthermore, the inner side wall of the sliding cavity 3 is inclined, and the connecting groove 4 and the limiting sliding groove 5 are opened along the inclined surface.
[0018] Furthermore, a connecting block 8 is connected to the back of the connecting plate 6 , one end of the connecting block 8 passes through the connecting groove 4 and is connected to a limiting slider 7 inside the limiting slide groove 5 , and the limiting slider 7 is engaged and slidably connected with the limiting slide groove 5 .
[0019] Furthermore, the position of the arc-shaped clamping plate 11 corresponds to the position of the bearing groove 13 .
[0020] Furthermore, fixing holes 15 are evenly formed on the back of the fixing plate 9 , and the fixing pins 14 are plugged into and fixedly connected with the fixing holes 15 .
[0021] The utility model first places the protein purification columns to be used into all the bearing grooves 13 respectively, and then drives the connecting plate 8 to move downward along the limiting slide groove 5 through the handle 10, so that the arc-shaped clamping plate 11 on the connecting plate 8 clamps the protein purification column firmly, and fixes the position of the connecting plate 6 through the fixing pin 14. When the protein purification column needs to be taken out, it is only necessary to pull out the fixing pin 14, adjust the handle 10, move the connecting plate 6 along the limiting slide groove 5, and keep the arc-shaped clamping plate 11 away from the protein purification column. Compared with the problem of low convenience in the placement and later removal of the protein purification column in the prior art, and insufficient stability during use, the method proposed in the utility model clamps the protein purification column firmly through all the arc-shaped clamping plates 11, and is also extremely convenient when taking out the protein purification column, which has high practicality.
[0022] Although the embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A protein purification column support mechanism, comprising a mounting frame (1) and a placement cavity (2), Features: The installation frame (1) is provided with a placement cavity (2) inside, a placement plate (12) is installed at the bottom of the inner cavity of the placement cavity (2), and a bearing groove (13) is evenly provided on the top surface of the placement plate (12). The inner cavity walls on both sides of the placement cavity (2) are provided with sliding cavities (3), and the surface of the sliding cavity (3) is provided with a connecting groove (4). A limiting sliding groove (5) is provided inside the connecting groove (4). Connecting plates (6) are symmetrically arranged on both sides of the placement cavity (2), and a plurality of arc-shaped clamping plates (11) are evenly arranged on the front of the connecting plate (6). A fixing plate (9) is connected in the middle of the back of the connecting plate (6), and a handle (10) is connected to the top of the surface of the fixing plate (9). Fixed latches (14) are slidably sleeved on the outer walls on both sides of the installation frame (1).
2. A protein purification column support structure according to claim 1, Features: The inner cavity side wall of the sliding cavity (3) is arranged to be inclined, and the connecting groove (4) and the limiting sliding groove (5) are opened along the inclined surface.
3. A protein purification column support structure according to claim 1, Features: The back of the connecting plate (6) is connected to a connecting block (8), one end of the connecting block (8) passes through the connecting groove (4) and is connected to a limiting slide block (7) inside the limiting slide groove (5), and the limiting slide block (7) is slidably connected to the limiting slide groove (5).
4. A protein purification column support mechanism according to claim 1, Features: The position of the arc-shaped clamping plate (11) corresponds to the position of the bearing groove (13).
5. A protein purification column support structure according to claim 1, Features: The back side of the fixing plate (9) is evenly provided with fixing holes (15), and the fixing pins (14) are plugged into and fixedly connected with the fixing holes (15).
