Membrane separation device for polypeptide rich in phenylalanine

By setting up a filter box and a liquid storage bucket in the separation barrel of the membrane separation device, and cleaning the filter net with a motor-driven brush plate, the problem of filter net blockage in the prior art is solved and the separation efficiency is improved.

CN222196223UActive Publication Date: 2024-12-20HUBEI QIANGYAO BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202420701892.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-08
Publication Date
2024-12-20
Estimated Expiration
2034-04-08

AI Technical Summary

Technical Problem

In existing polypeptide membrane separation devices that are rich in phenylalanine, the filter mesh is easily blocked by large impurities, which affects the filtration efficiency.

Method used

A membrane separation device including a collection barrel and a separation barrel is designed. The separation barrel is equipped with a filter box and a liquid storage barrel. The bottom of the filter box is equipped with a through hole and a filter net, and the top is equipped with a motor-driven rotating shaft and a brush plate. Used to clean the filter mesh, prevent clogging, and improve separation efficiency through multiple mesh barrels and separation membranes.

Benefits of technology

It effectively prevents impurities from being blocked, improves filtration and separation efficiency, and ensures continuous operation and efficient operation of the device.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of membrane separation, and discloses a membrane separation device for polypeptide rich in phenylalanine, which comprises a collection barrel and a separation barrel, a support column is rotatably arranged at the inner bottom of the collection barrel, the top of the support column is fixedly connected with a chassis, the top of the chassis is fixedly connected with the separation barrel, and the separation barrel is fixedly connected with the support column. A filter box is arranged at the top of the separation barrel, a liquid storage barrel is fixedly connected to the bottom of the filter box, a through hole communicating with the liquid storage barrel is formed in the bottom of the filter box, a filter screen is fixedly connected into the through hole, a first motor is fixedly connected to the top of the filter box, and a rotating shaft is fixedly connected to the output end of the first motor; and the bottom of the rotating shaft movably penetrates through the interior of the near filter box and is fixedly connected with a brush plate. According to the membrane separation device for the polypeptide rich in phenylalanine, the first motor drives the rotating shaft and the brush plate to rotate, so that the filter screen is cleaned, blockage is prevented, and the problem that the filter efficiency is influenced by the blockage of the filter screen by impurities is solved.
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Description

Technical Field

[0001] The utility model relates to the technical field of membrane separation, in particular to a membrane separation device for polypeptides rich in phenylalanine. Background Art

[0002] Phenylalanine, whose chemical name is 2-amino-3-phenylpropionic acid, is an organic compound with the chemical formula C9H11NO2 and a molecular weight of 165.19. It is a kind of α-amino acid. The optical isomer with biological activity is L-phenylalanine. Phenylalanine is a white crystal or crystalline powder solid at room temperature, sublimates under reduced pressure, is soluble in water, and is insoluble in methanol, ethanol, and ether.

[0003] A membrane separation device for phenylalanine-rich polypeptides provided in the Chinese utility model patent application disclosure CN 214344922 U comprises a base, a reciprocating motion component is arranged on the top of the base, a separation box is fixedly connected to the top of the reciprocating motion component, a rotating column is rotatably connected in the separation box, a bottom cylinder cover is connected to the top of the rotating column, a gear ring is fixedly connected to the outer side of the bottom cylinder cover, a first gear is meshingly connected to the gear ring, the first gear is connected to the output end of a first motor, a net cylinder is fixedly connected to the outer side of the bottom cylinder cover, a separation membrane is connected to the inner side of the net cylinder, a retaining ring is fixedly connected to the upper part of the separation box, a filter net is placed on the retaining ring, and a box cover is hinged on the top of the separation box; some larger impurities in the solution can be filtered out through the filter net, the first motor drives the first gear to rotate, the first gear drives the bottom cylinder cover to rotate through the gear ring, the bottom cylinder cover drives the net cylinder and the separation membrane to rotate, so as to accelerate the separation of the solution in the net cylinder, and at the same time, the separation box is driven to do reciprocating motion through the reciprocating motion component, so that the separation speed is fast and the separation effect is good.

[0004] However, the above-mentioned prior art first filters out some larger impurities in the solution of the phenylalanine-rich polypeptide through a filter net. The larger impurities will clog the filter net during filtration, affecting the filtration efficiency. Therefore, a membrane separation device for phenylalanine-rich polypeptides is urgently needed. Utility Model Content

[0005] The utility model aims to provide a membrane separation device for polypeptides rich in phenylalanine to solve the problems raised in the above background technology.

[0006] In order to solve the above technical problems, the utility model provides the following technical solutions: a membrane separation device for phenylalanine-rich polypeptides, comprising a collecting barrel and a separating barrel, wherein the inner bottom of the collecting barrel is rotatably provided with a support, the top of the support is fixedly connected with a chassis, the top of the chassis is fixedly connected with the separating barrel, and the top of the separating barrel is provided with a filter box;

[0007] The bottom of the filter box is fixedly connected to a liquid storage barrel, the bottom of the filter box is provided with a through hole connected to the liquid storage barrel, a filter screen is fixedly connected in the through hole, the top of the filter box is fixedly connected to a first motor, the output end of the first motor is fixedly connected to a rotating shaft, the bottom of the rotating shaft movably passes through the filter box and is fixedly connected to a brush plate.

[0008] Preferably, a plurality of mesh cylinders are fixedly connected to the inner bottom of the separation barrel, and separation membranes are respectively arranged on the outer surfaces of the plurality of mesh cylinders. A first liquid outlet pipe is arranged at the bottom of the separation barrel.

[0009] The inner bottom of the separation barrel is fixedly connected with a plurality of mesh cylinders, and the outer surface of the mesh cylinder is provided with a separation membrane, which is used to separate the polypeptides. The plurality of mesh cylinders correspond to a plurality of liquid down pipes, which facilitates the injection of liquid into the mesh cylinder and improves the separation efficiency.

[0010] Preferably, a plurality of liquid down pipes are fixedly connected to the bottom of the liquid storage barrel, sealing pads are respectively provided on the surfaces of the plurality of liquid down pipes, the plurality of liquid down pipes are respectively matched with the mesh cylinder, and the plurality of liquid down pipes are respectively inserted into the mesh cylinder.

[0011] Preferably, a liquid injection pipe is movably provided on the top of the filter box, and a sealing door is provided on the right side of the filter box.

[0012] A movable liquid injection pipe is provided on the top of the filter box for injecting the liquid to be treated into the filter box. A sealed door is provided on the right side of the filter box for maintaining and cleaning the components inside the filter box.

[0013] Preferably, an electric hydraulic rod is fixedly connected to the top of the chassis, a connecting plate is fixedly connected to the top of the electric hydraulic rod, and the right side of the connecting plate is fixedly connected to the filter box.

[0014] Preferably, a second liquid outlet pipe is provided on the right side of the collecting barrel, a protection box is fixedly connected to the interior of the collecting barrel, a second motor is provided inside the protection box, and an output shaft of the second motor movably passes through the protection box and is fixedly connected to the first gear.

[0015] A second liquid outlet pipe is provided on the right side of the collecting barrel for discharging the liquid in the collecting barrel. A protective box is provided inside the collecting barrel. A first motor and a first gear are installed inside the protective box. The output shaft of the first motor movably passes through the protective box and is fixedly connected to the first gear. The first gear is meshed with the second gear on the surface of the pillar to drive the rotation of the pillar and the separation barrel.

[0016] Preferably, a second gear is fixedly connected to the surface of the pillar, and the second gear is meshed with the first gear.

[0017] Compared with the prior art, the beneficial effects achieved by the utility model are:

[0018] First, in the utility model, the separation barrel is used for separating polypeptides, and the collection barrel is used for collecting the separated liquid. A rotatable pillar is provided at the inner bottom of the collection barrel, and a chassis is fixedly connected to the top of the pillar. The chassis is fixedly connected to the separation barrel, so that the separation barrel can be rotated on the pillar for subsequent operation and processing. A filter box is provided on the top of the separation barrel for filtering the incoming liquid. A liquid storage barrel is connected to the bottom of the filter box for temporarily storing the filtered liquid. A through hole is provided at the bottom of the filter box, and a filter screen is installed in the through hole for filtering impurities in the liquid. A first motor is installed on the top of the filter box, and a rotating shaft is connected to the output end of the first motor. The bottom of the rotating shaft is movable A brush plate is fixedly connected to the filter box and is penetrated by the first motor, so that the rotating shaft and the brush plate are rotated, thereby cleaning the filter screen and preventing clogging, thus solving the problem of impurities clogging the filter screen and affecting the filtration efficiency. A plurality of mesh cylinders are fixedly connected to the inner bottom of the separation barrel, and a separation membrane is arranged on the outer surface of the mesh cylinder. The separation membrane is used to separate the polypeptides, and the plurality of mesh cylinders correspond to a plurality of liquid down pipes for facilitating the injection of liquid into the mesh cylinder, thereby improving the separation efficiency. A first liquid outlet pipe is arranged at the bottom of the separation barrel for discharging the separated liquid, and a movable liquid injection pipe is arranged on the top of the filter box for injecting the liquid to be treated into the filter box. A sealing door is arranged on the right side of the filter box for maintaining and cleaning the components inside the filter box.

[0019] Second, in the utility model, an electric hydraulic rod is fixedly connected to the top of the chassis, a connecting plate is fixedly connected to the top of the electric hydraulic rod, the right side of the connecting plate is fixedly connected to the filter box, the electric hydraulic rod can control the height and position of the filter box for easy operation and maintenance, a second liquid outlet pipe is provided on the right side of the collecting barrel for discharging the liquid in the collecting barrel, a protective box is provided inside the collecting barrel, a second motor and a first gear are installed inside the protective box, the output shaft of the second motor movably passes through the protective box and is fixedly connected to the first gear, the first gear is meshed with the second gear on the surface of the pillar, and is used to drive the rotation of the pillar and the separation barrel, thereby improving the separation efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the structure of the utility model;

[0021] Figure 2 It is a schematic diagram of the structure of the utility model;

[0022] Figure 3 It is a schematic diagram of the structure of the utility model;

[0023] Figure 4 It is a schematic diagram of the structure of the utility model.

[0024] Among them: 1. collecting barrel; 2. separating barrel; 11. supporting column; 12. chassis; 3. filtering box; 31. liquid storage barrel; 32. filtering net; 33. first motor; 34. rotating shaft; 35. brush plate; 21. mesh cylinder; 22. separating membrane; 23. first liquid outlet pipe; 36. lower liquid pipe; 37. sealing pad; 38. liquid injection pipe; 13. electric hydraulic rod; 14. second liquid outlet pipe; 15. protective box; 16. second motor; 17. first gear; 18. second gear. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0026] The utility model provides the following technical solutions:

[0027] Embodiment 1

[0028] See also Figure 1 , Figure 2 , Figure 3 A membrane separation device for phenylalanine-rich polypeptides comprises a collecting barrel 1 and a separating barrel 2, wherein a support 11 is rotatably provided at the inner bottom of the collecting barrel 1, a bottom plate 12 is fixedly connected to the top of the support 11, the top of the bottom plate 12 is fixedly connected to the separating barrel 2, and a filter box 3 is provided at the top of the separating barrel 2;

[0029] A liquid storage barrel 31 is fixedly connected to the bottom of the filter box 3, a through hole communicating with the liquid storage barrel 31 is opened at the bottom of the filter box 3, a filter screen 32 is fixedly connected in the through hole, a first motor 33 is fixedly connected to the top of the filter box 3, a rotating shaft 34 is fixedly connected to the output end of the first motor 33, and the bottom of the rotating shaft 34 movably passes through the filter box 3 and is fixedly connected to a brush plate 35.

[0030] A plurality of mesh cylinders 21 are fixedly connected to the inner bottom of the separation barrel 2 , and separation membranes 22 are respectively arranged on the outer surfaces of the plurality of mesh cylinders 21 . A first liquid outlet pipe 23 is arranged at the bottom of the separation barrel 2 .

[0031] A plurality of liquid down pipes 36 are fixedly connected to the bottom of the liquid storage barrel 31 . Sealing pads 37 are respectively arranged on the surfaces of the plurality of liquid down pipes 36 . The plurality of liquid down pipes 36 are respectively matched with the mesh cylinder 21 , and the plurality of liquid down pipes 36 are respectively inserted into the mesh cylinder 21 .

[0032] A liquid injection pipe 38 is movably provided on the top of the filter box 3 , and a sealing door is provided on the right side of the filter box 3 .

[0033] Through the above technical solution, the separation barrel 2 is used to separate the polypeptides, and the collection barrel 1 is used to collect the separated liquid. A rotatable pillar 11 is provided at the inner bottom of the collection barrel 1. A chassis 12 is fixedly connected to the top of the pillar 11. The chassis 12 is fixedly connected to the separation barrel 2, so that the separation barrel 2 can rotate on the pillar 11 to facilitate subsequent operation and processing. A filter box 3 is provided on the top of the separation barrel 2 for filtering the incoming liquid. A liquid storage barrel 31 is connected to the bottom of the filter box 3 for temporarily storing the filtered liquid. A through hole is provided at the bottom of the filter box 3, and a filter screen 32 is installed in the through hole for filtering impurities in the liquid. A first motor 33 is installed on the top of the filter box 3, and a rotating shaft 34 is connected to the output end of the first motor 33. The bottom of the rotating shaft 34 is movable through The filter box 3 is fixedly connected with a brush plate 35. The first motor 33 drives the rotating shaft 34 and the brush plate 35 to rotate, so as to clean the filter screen 32 and prevent clogging, thereby solving the problem that impurities clog the filter screen 32 and affect the filtration efficiency. A plurality of mesh cylinders 21 are fixedly connected to the inner bottom of the separation barrel 2. A separation membrane 22 is arranged on the outer surface of the mesh cylinder 21. The separation membrane 22 is used to separate the polypeptides, and the plurality of mesh cylinders 21 correspond to a plurality of liquid down pipes 36 to facilitate the injection of liquid into the mesh cylinder 21, thereby improving the separation efficiency. A first liquid outlet pipe 23 is arranged at the bottom of the separation barrel 2 for discharging the separated liquid. A movable liquid injection pipe 38 is arranged at the top of the filter box 3 for injecting the liquid to be treated into the filter box 3. A sealing door is arranged on the right side of the filter box 3 for maintaining and cleaning the components inside the filter box 3.

[0034] Embodiment 2

[0035] See also Figure 3 , Figure 4 On the basis of the first embodiment, it is further obtained that: the top of the chassis 12 is fixedly connected with an electric hydraulic rod 13, the top of the electric hydraulic rod 13 is fixedly connected with a connecting plate, and the right side of the connecting plate is fixedly connected with the filter box 3.

[0036] A second liquid outlet pipe 14 is arranged on the right side of the collecting barrel 1 , a protection box 15 is fixedly connected to the inside of the collecting barrel 1 , a second motor 16 is arranged inside the protection box 15 , and an output shaft of the second motor 16 movably passes through the protection box 15 and is fixedly connected to a first gear 17 .

[0037] A second gear 18 is fixedly connected to the surface of the pillar 11 , and the second gear 18 is meshed with the first gear 17 .

[0038] Through the above technical scheme, an electric hydraulic rod 13 is fixedly connected to the top of the chassis 12, and a connecting plate is fixedly connected to the top of the electric hydraulic rod 13. The right side of the connecting plate is fixedly connected to the filter box 3. The electric hydraulic rod 13 can control the height and position of the filter box 3 for easy operation and maintenance. A second liquid outlet pipe 14 is provided on the right side of the collecting barrel 1 for discharging the liquid in the collecting barrel 1. A protective box 15 is provided inside the collecting barrel 1. A second motor 16 and a first gear 17 are installed inside the protective box 15. The output shaft of the second motor 16 movably passes through the protective box 15 and is fixedly connected to the first gear 17. The first gear 17 is meshed with the second gear 18 on the surface of the pillar 11 to drive the rotation of the pillar 11 and the separation barrel 2, thereby improving the separation efficiency.

[0039] In actual operation, when this device is in use, liquid is injected from the injection pipe 38 into the filter box 3, and the filter screen 32 in the filter box 3 filters large impurities. To prevent the filter screen 32 from being blocked, the first motor 33 drives the rotating shaft 34 to rotate so that the brush plate 35 cleans the filter screen 32. The filtered liquid enters the liquid storage barrel 31, and enters the mesh tube 21 through multiple liquid down pipes 36 at the bottom of the liquid storage barrel 31. The liquid is separated by the mesh tube 21 and the separation membrane 22 on the surface. After separation, it is discharged from the first liquid outlet pipe 23 at the bottom of the separation barrel 2 into the collection barrel 1, and then discharged from the second liquid outlet pipe 14 on the right side of the collection barrel 1, thereby completing the separation work.

[0040] Although the embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit thereof, and the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A membrane separation device for phenylalanine-rich polypeptides, comprising a collecting barrel (1) and a separating barrel (2), Features: The inner bottom of the collecting barrel (1) is rotatably provided with a support (11), the top of the support (11) is fixedly connected to a chassis (12), the top of the chassis (12) is fixedly connected to the separation barrel (2), and the top of the separation barrel (2) is provided with a filter box (3); The bottom of the filter box (3) is fixedly connected to a liquid storage barrel (31), the bottom of the filter box (3) is provided with a through hole communicating with the liquid storage barrel (31), a filter screen (32) is fixedly connected in the through hole, the top of the filter box (3) is fixedly connected to a first motor (33), the output end of the first motor (33) is fixedly connected to a rotating shaft (34), the bottom of the rotating shaft (34) movably passes through the filter box (3) and is fixedly connected to a brush plate (35).

2. A membrane separation device for phenylalanine-rich polypeptides according to claim 1, Features: A plurality of net cylinders (21) are fixedly connected to the inner bottom of the separation barrel (2), and separation membranes (22) are respectively arranged on the outer surfaces of the plurality of net cylinders (21). A first liquid outlet pipe (23) is arranged at the bottom of the separation barrel (2).

3. A membrane separation device for phenylalanine-rich polypeptides according to claim 1, Features: A plurality of liquid lowering pipes (36) are fixedly connected to the bottom of the liquid storage barrel (31), and sealing pads (37) are respectively provided on the surfaces of the plurality of liquid lowering pipes (36). The plurality of liquid lowering pipes (36) are respectively adapted to the net cylinder (21), and the plurality of liquid lowering pipes (36) are respectively inserted into the net cylinder (21).

4. A membrane separation device for phenylalanine-rich polypeptides according to claim 1, Features: A liquid injection pipe (38) is movably provided on the top of the filter box (3), and a sealing door is provided on the right side of the filter box (3).

5. A membrane separation device for phenylalanine-rich polypeptides according to claim 1, Features: The top of the chassis (12) is fixedly connected to an electric hydraulic rod (13), the top of the electric hydraulic rod (13) is fixedly connected to a connecting plate, and the right side of the connecting plate is fixedly connected to the filter box (3).

6. A membrane separation device for phenylalanine-rich polypeptides according to claim 1, Features: A second liquid outlet pipe (14) is arranged on the right side of the collecting barrel (1), a protection box (15) is fixedly connected to the interior of the collecting barrel (1), a second motor (16) is arranged inside the protection box (15), and an output shaft of the second motor (16) movably passes through the protection box (15) and is fixedly connected to a first gear (17).

7. A membrane separation device for phenylalanine-rich polypeptides according to claim 1, Features: A second gear (18) is fixedly connected to the surface of the pillar (11), and the second gear (18) is meshed with the first gear (17).