Liquid level detection device for liquid chromatogram mobile phase

Abstract

The utility model provides a liquid level detection device for a liquid chromatogram mobile phase. The liquid level detection device comprises a mounting seat, the cleaning unit is arranged on the mounting seat and is used for cleaning the outer wall of the sample needle; the cleaning unit comprises a mounting bottom plate, and a cleaning tank is fixedly arranged at the bottom of the mounting bottom plate; a waste liquid discharging port is formed in the bottom of the cleaning tank, a first tank opening and a second tank opening are formed in the top face of the cleaning tank, and an air inlet connector and a liquid inlet connector are formed in the positions, away from the first tank opening and the second tank opening, of the two sides of the cleaning tank. A cleaning liquid annular cavity and a nitrogen annular cavity are formed in the first notch and the second notch correspondingly. According to the liquid level detection sensor, secondary cleaning and blow-drying actions can be performed on the sample needle, the cleanliness of the sample needle is guaranteed, and meanwhile the sensitivity of the liquid level detection sensor is improved.

Description

Technical Field

[0001] The utility model relates to a liquid level detection device for a mobile phase of a liquid chromatography. Background Art

[0002] Liquid chromatography mobile phase is a substance that carries the components to be tested forward in liquid chromatography analysis. The choice of mobile phase has a significant impact on the separation effect and the reliability of sample separation. According to the characteristics of liquid chromatography technology, the mobile phase can be a liquid, a gas or a supercritical fluid. In classical liquid chromatography, the mobile phase flows slowly through the chromatographic column by gravity, so the particle size of the stationary phase cannot be too small (about 100μm~150μm), which leads to low separation efficiency, slow analysis speed, and complex operation. In order to overcome these shortcomings, high performance liquid chromatography (HPLC) was developed, in which the mobile phase is delivered by a high-pressure infusion pump with a fast flow rate, and a fine particle stationary phase (5~10μm) is used, which greatly improves the separation efficiency and analysis speed.

[0003] However, in the actual operation process, different liquid level parameters need to be set due to different detection experiments. If the parameter configuration is incorrect, it will cause empty aspiration or aspiration of sediment in the lower layer, causing the experiment to fail. At the same time, the sample vial can only be injected once. If the injection experiment needs to be repeated, the liquid level parameters need to be reset. After the injection, the parameters need to be modified back. Such operations will lead to poor liquid aspiration accuracy of the equipment and certain errors, which is not conducive to subsequent experiments. Moreover, there is no reasonable way to handle the sample needle after use, resulting in some impurities remaining on the sample needle, which in turn affects the use of subsequent experiments. Therefore, designing a liquid level detection device for liquid chromatography mobile phase that is conducive to cleaning the sample needle and improving the liquid aspiration accuracy is the research direction of the utility model. Utility Model Content

[0004] The utility model provides a liquid level detection device for liquid chromatography mobile phase, which can effectively solve the above problems.

[0005] The utility model is achieved in this way:

[0006] A liquid level detection device for a liquid chromatography mobile phase, comprising:

[0007] Mounting seat;

[0008] A cleaning unit is arranged on the mounting seat and is used for cleaning the outer wall of the sample needle; the cleaning unit comprises a mounting base plate, a cleaning groove is fixedly arranged at the bottom of the mounting base plate; a waste liquid discharge port is arranged at the bottom of the cleaning groove, a first notch and a second notch are formed on the top surface of the cleaning groove, an air inlet interface and a liquid inlet interface are arranged on both sides of the cleaning groove and away from the first notch and the second notch, a cleaning liquid annular cavity- and a nitrogen annular cavity- are respectively formed inside the first notch and the second notch, a plurality of umbrella-shaped liquid outlets- and umbrella-shaped air outlets- are respectively formed on the inner walls of the first notch and the second notch, and a rinsing chamber and a blow-drying chamber respectively connected to the first notch and the second notch are formed inside the cleaning groove;

[0009] The driving unit is arranged on the mounting seat and is used to realize the up-down and forward-backward movement of the sample needle and automatic sampling.

[0010] As a further improvement, the plurality of umbrella-shaped liquid outlets - and the plurality of umbrella-shaped air outlets - all have an inclination R, wherein R is greater than or equal to 20 degrees or less than or equal to 135 degrees.

[0011] As a further improvement, the driving unit includes a guide rail bracket, a sliding seat is slidably arranged on the guide rail bracket, and a driving motor for driving the sample needle to move back and forth is fixedly arranged at one end of the guide rail bracket, and the driving motor is cooperated with a guide member for the sample needle to move back and forth; a lifting motor is arranged on one side of the sliding seat, one end of the lifting motor is connected to a connecting seat connected to the sliding seat, so that the lifting motor drives the sliding seat up and down through the connecting seat, and a lifting guide member for limiting the lifting height of the connecting seat is arranged on the top surface of the sliding seat, a liquid level detection sensor is arranged on the top surface of the connecting seat at a position away from the sliding seat, a fixing kit is fixedly arranged at one end of the connecting seat, and the fixing kit is used to fix the sample needle, and a forward and backward movement position sensor is arranged on one side of the connecting seat and away from the liquid level detection sensor.

[0012] As a further improvement, a rotating unit is arranged on the mounting seat, and the rotating unit includes a turntable arranged on the top surface of the mounting seat, and the turntable is used to place the sample injection bottle.

[0013] As a further improvement, a second fixed seat is fixedly provided at the bottom of the mounting seat and is used to fix the rotating motor, and the rotating motor cooperates with the driven wheel to drive the turntable to rotate. A motor tensioning seat is also provided between the rotating motor and the driven wheel. A waste liquid tank is fixedly provided at the bottom of the mounting seat and close to the driven wheel, and a No. 1 sensor for detecting the position of the turntable is provided on one side of the top of the mounting seat.

[0014] The top surface of the turntable is formed with a plurality of sample bottle positions for placing bottle bodies, and washing reagent bottle positions and drain positions are arranged at the head and tail ends of the plurality of sample bottle positions; the bottom of the drain position is hollow.

[0015] An injection unit is arranged on the mounting seat; the injection unit includes an injection box, a mounting bracket arranged on the injection box, the front end face of the injection box is connected to an injection pump, a first fixed seat is arranged on the mounting bracket, a sample needle bottom position sensor and a sample needle top position sensor are arranged on one side of the first fixed seat, and the sample needle bottom position sensor is located above the sample needle top position sensor.

[0016] A rinsing box is arranged on the mounting seat and close to the cleaning unit, and a switching valve module is arranged on the front end surface of the rinsing box.

[0017] The beneficial effects of the utility model are:

[0018] (1) The driving unit in the utility model includes an up-and-down moving mechanism and a left-and-right moving mechanism. The two sets of mechanism rotation modules cooperate with each other. The up-and-down moving mechanism controls the sample needle to detect the liquid level and pipette liquid in the vertical direction of the turntable working position (the pipetting liquid is moved downward while pipetting liquid, thereby improving the pipetting accuracy and reducing the contamination of the outer wall of the sample needle); the front-and-back moving mechanism controls the sample needle to switch between the turntable working position and the first air blowing slot and the second air blowing slot. After the injection, the front-and-back translation mechanism cooperates with the up-and-down moving mechanism to drive the sample needle back to the first air blowing slot or the second air blowing slot to rinse and dry the outer wall of the sample needle.

[0019] (2) In the present invention, in order to reduce the interference between the eight samples (sample bottles), the sample needle needs to be cleaned after each sample is analyzed and injected. The cleaning module is provided with a cleaning liquid annular cavity and a nitrogen annular cavity. The cleaned sample needle is blown dry with nitrogen, which can effectively improve the cleanliness of the sample needle, thereby ensuring the sensitivity of the capacitive sensor.

[0020] (3) In the present invention, a plurality of umbrella-shaped liquid outlets and a plurality of umbrella-shaped air outlets are provided with an inclination R, wherein R is greater than or equal to 20 degrees or less than or equal to 135 degrees. In one embodiment, R is approximately 65 degrees. The advantage of such a setting is that the liquid sprayed from the umbrella-shaped liquid outlet can be ensured to directly act on the sample needle, and the cleaning is more comprehensive. Furthermore, the umbrella-shaped air outlet can effectively disperse the nitrogen in the annular cavity and spray it obliquely downward to the outer wall of the sample needle, so that the air cavity forms a downward airflow, and the cleaning liquid attached to the outer wall is taken away in time.

[0021] (4) In the present invention, a plurality of umbrella-shaped liquid outlets and a plurality of umbrella-shaped air outlets are respectively arranged in the cleaning liquid annular cavity and the nitrogen annular cavity, thereby achieving 360-degree all-round cleaning and drying of the sample needle.

[0022] (5) The utility model also has the characteristics of high detection sensitivity, low carryover contamination rate, compact structure, and convenient peripheral matching mechanism design. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the technical solution of the implementation mode of the utility model, the drawings required for use in the implementation mode will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the utility model and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other relevant drawings can be obtained based on these drawings without paying creative work.

[0024] Figure 1 It is the front view of the utility model.

[0025] Figure 2 It is a structural schematic diagram of the injection unit of the utility model.

[0026] Figure 3 It is a structural schematic diagram of the cleaning unit of the utility model.

[0027] Figure 4 It is a structural schematic diagram of the installation base plate of the utility model.

[0028] Figure 5 It is a structural schematic diagram of the cleaning tank of the utility model.

[0029] Figure 6 It is a bottom view of the installation base plate of the utility model.

[0030] Figure 7 It is a cross-sectional view of the first notch and the second notch of the utility model.

[0031] Figure 8 It is a structural schematic diagram of the rotating unit of the utility model.

[0032] Fig. 9 It is a structural schematic diagram of a turntable of the utility model.

[0033] Description of Figure Numbers:

[0034] 1. Mounting seat;

[0035] 2. Cleaning unit; 20. Mounting base plate; 200. Cleaning tank; 202. First notch; 202-0. Cleaning liquid annular cavity; 202-1. Umbrella-shaped liquid outlet; 2001. Waste discharge interface; 2003. Second notch; 2003-0. Nitrogen annular cavity; 2003-1. Umbrella-shaped air outlet; 2004. Air inlet interface; 2006. Liquid inlet interface; 2007. Rinse cavity; 2008. Dry cavity; 21. Driving unit; 210. Sliding seat; 211. Driving motor; 212. Lifting guide; 213. Liquid level detection sensor; 214. Guide; 215. Forward and backward motion position sensor; 216. Fixing kit; 217. Lifting motor;

[0036] 3. Injection unit; 30. Injection box; 31. Mounting bracket; 32. Injection pump; 33. First fixing seat; 34. Sample needle bottom position sensor; 35. Sample needle top position sensor;

[0037] 4. Rotating unit; 41. Second fixed seat; 42. Rotating motor; 43. Driven wheel; 44. Motor tensioning seat; 45. Turntable; 450. Washing reagent bottle position; 451. Drain position; 452. Sample bottle position; 46. Sensor No. 1; 47. Waste liquid tank;

[0038] 5. Eluent box; 6. Switching valve module. DETAILED DESCRIPTION

[0039] In order to make the purpose, technical scheme and advantages of the embodiments of the utility model clearer, the technical scheme in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work belong to the scope of protection of the utility model. Therefore, the following detailed description of the embodiments of the utility model provided in the drawings is not intended to limit the scope of the utility model for which protection is sought, but merely represents the selected embodiments of the utility model. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work belong to the scope of protection of the utility model.

[0040] In the description of the present invention, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present invention, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0041] Reference Figure 1-9 As shown, a liquid level detection device for a mobile phase of a liquid chromatography comprises a mounting seat 1; a cleaning unit 2, which is arranged on the mounting seat 1 and is used to clean the outer wall of a sample needle; the cleaning unit 2 comprises a mounting base 20, and a cleaning tank 200 is fixedly arranged at the bottom of the mounting base 20; a waste liquid discharge port 2001 is arranged at the bottom of the cleaning tank 200, and a first notch 202 and a second notch 2003 are formed on the top surface of the cleaning tank 200, and both sides of the cleaning tank 200 are away from the first notch 202 and the second notch 2003. An air inlet interface 2004 and a liquid inlet interface 2006 are provided, and a cleaning liquid annular cavity 202-0 and a nitrogen annular cavity 2003-0 are formed inside the first slot 202 and the second slot 2003 respectively, and a plurality of umbrella-shaped liquid outlets 202-1 and umbrella-shaped air outlets 2003-1 are formed on the inner walls of the first slot 202 and the second slot 2003 respectively, and a rinsing cavity 2007 and a drying cavity 2008 which are respectively connected to the first slot 202 and the second slot 2003 are formed inside the cleaning tank 200.

[0042] The plurality of umbrella-shaped liquid outlets 202-1 and the plurality of umbrella-shaped air outlets 2003-1 all have an inclination R, wherein R is greater than or equal to 20 degrees or less than or equal to 135 degrees. In one embodiment, R is about 65 degrees. The advantage of such a setting is that the liquid sprayed from the umbrella-shaped liquid outlet 202-1 can be ensured to directly act on the sample needle, and the cleaning is more comprehensive. Furthermore, the umbrella-shaped air outlet 2003-1 can effectively disperse the nitrogen in the annular cavity and spray it obliquely downward to the outer wall of the sample needle, and the air cavity forms a downward airflow, which promptly takes away the cleaning liquid attached to the outer wall. More specifically, if R is too large, the umbrella-shaped liquid outlet 202-1 or the umbrella-shaped air outlet 2003-1 will not be able to directly act on the sample needle, and the desired effect will not be achieved; if R is too small, the umbrella-shaped liquid outlet 202-1 or the umbrella-shaped air outlet 2003-1 will be parallel to the sample needle, and the umbrella-shaped air outlet 2003-1 will not be able to form a downward airflow with the nitrogen annular cavity 2003-0, and will not be able to take away the liquid on the outer wall of the sample needle.

[0043] The nitrogen annular cavity 2003-0 includes but is not limited to using nitrogen to blow dry the sample needle, and can also be an inert gas such as argon or helium. These gases are characterized by high purity and low cost, and can be used to blow dry the sample needle or as an auxiliary gas for the mobile phase. Of course, the specific gas to be selected also needs to be determined according to the experimental conditions and sample properties, because different gases may interact differently with the sample, which will affect the separation effect and detection sensitivity. Therefore, comprehensive consideration and experimental verification are required when selecting the gas to ensure the accuracy and reliability of the experimental results.

[0044] The driving unit 21 is arranged on the mounting base 1 and is used to realize the up and down forward and backward movement of the sample needle and automatic injection; the driving unit 21 includes a guide rail bracket, a sliding base 210 is slidably arranged on the guide rail bracket, and a driving motor 211 for driving the sample needle to move forward and backward is fixedly arranged at one end of the guide rail bracket, and the driving motor 211 is matched with a guide member 214 for the forward and backward movement of the sample needle; a lifting motor 217 is arranged on one side of the sliding base 210, one end of the lifting motor 217 is connected to the connecting base connected to the sliding base 210, so that the lifting motor 217 drives the sliding base 210 to move up and down through the connecting base, and a lifting guide member 212 for limiting the lifting height of the connecting base is arranged on the top surface of the sliding base 210, and a liquid level detection sensor 213 is arranged on the top surface of the connecting base at a position away from the sliding base 210, and a fixing kit 216 is fixedly arranged at one end of the connecting base, and the fixing kit 216 is used to fix the sample needle, and a forward and backward movement position sensor 215 is arranged on one side of the connecting base and away from the liquid level detection sensor 213. It should be noted that the liquid level detection sensor 213 is a capacitive sensor, which is a type of sensor that converts the measured non-electrical quantity into a capacitance change. It has high sensitivity, does not require direct contact between electrodes and liquids, and is suitable for liquid level detection of extremely fine inner diameters of chromatographic sample needles. Since the sample needle fixing part adopts a plastic structure, it can effectively reduce noise interference to the capacitive sensor, thereby facilitating the use of the device.

[0045] A rotating unit 4 is arranged on the mounting base 1, and the rotating unit 4 includes a turntable 45 arranged on the top surface of the mounting base 1, and the turntable 45 is used to place the sample bottle; a second fixed seat 41 is fixedly arranged at the bottom of the mounting base 1, and is used to fix the rotating motor 42, and the rotating motor 42 cooperates with the driven wheel 43 to drive the turntable 45 to rotate, and a motor tensioning seat 44 is also arranged between the rotating motor 42 and the driven wheel 43, a waste liquid tank 47 is fixedly arranged at the bottom of the mounting base 1 and close to the driven wheel 43, and a sensor No. 1 46 for detecting the position of the turntable 45 is arranged on one side of the top of the mounting base 1.

[0046] The top surface of the turntable 45 is formed with a plurality of sample bottle positions 452 for placing bottles, and at the head and tail ends of the plurality of sample bottle positions 452 are arranged immersion reagent bottle positions 450 and drain positions 451; the bottom of the drain position 451 is hollow.

[0047] A rinsing box 5 is arranged on the mounting base 1 and near the cleaning unit 2, and a switching valve module 6 is arranged on the front end surface of the rinsing box 5. The switching valve module 6 is a prior art and will not be described in detail here.

[0048] The injection unit 3 is arranged on the mounting base 1 and is used to clean the inner wall of the sample needle. The injection unit 3 includes an injection box 30, a mounting bracket 31 arranged on the injection box 30, a front end surface of the injection box 30 is connected to an injection pump 32, a first fixing base 33 is arranged on the mounting bracket 31, and a sample needle bottom position sensor 34 and a sample needle top position sensor 35 are arranged on one side of the first fixing base 33, and the sample needle bottom position sensor 34 is located above the sample needle top position sensor 35.

[0049] The equipment of the utility model also includes sampling, cleaning and drying actions, which are as follows:

[0050] S1. Turn on the detection equipment and check whether the mobile phase is sufficient. If not, replenish it;

[0051] S2, filtering the mobile phase through a mixed filter membrane to remove impurities therein;

[0052] S3. Perform ultrasonic degassing on the filtered mobile phase to remove the gas in it, prevent the gas from entering the chromatographic column and damaging the chromatographic column, affecting the column efficiency, and start the instrument power supply, computer monitor, host and other equipment to ensure normal display. Check whether the deuterium lamp is on, and whether the pump pressure is too high after turning on the pump. If there is any abnormality, it should be eliminated first. Replace the appropriate mobile phase according to the sample to be tested, set the appropriate detection wavelength and flow rate, turn the pump's drain valve 180° counterclockwise, open the drain valve, start the pump, and after checking that the flow rate is stable and there are no bubbles, turn the drain valve clockwise to the bottom, close the drain valve, and if there are still bubbles in the pipeline, repeat the above steps until all the bubbles are exhausted;

[0053] S4, injecting samples, placing the sample bottle on the sample bottle position 452 on the turntable 45, and then the sample needle used in conjunction with the drive unit 21 absorbs the supernatant in the sample bottle, and the liquid level detection sensor 213 senses the depth of the sample needle descending;

[0054] S5. After the injection is completed, the driving motor 211 drives the sample needle to move to a suitable position, and then the lifting motor 217 drives the sample needle to move down and insert it into the empty position 451. At this time, the switching valve module 6 is started, the injection pump 32 is cut in, and the inner wall of the sample needle is cleaned;

[0055] S6, after the inner wall of the sample needle is cleaned, the sample needle is driven up by the lifting motor 217, and the driving motor 211 drives the sample needle to move to a suitable position, and the lifting motor 217 is started again, and the sample needle is inserted into the immersion reagent bottle position 450 for rinsing;

[0056] S7, after the rinsing is completed, the sample needle enters the cleaning liquid annular cavity 202-0 through the first notch 202 via the driving unit 21, the elution pump is turned on, and the cleaning liquid is sprayed on the outer wall of the sample needle to rinse the outer wall of the sample needle, and the umbrella-shaped liquid outlet 202-1 disperses the cleaning liquid annular cavity 202-0 and flows out from the waste discharge interface 2001 in time;

[0057] S8, after the elution is completed, the sample needle is moved to the second notch 2003 through the driving unit 21 and inserted into the nitrogen annular cavity 2003-0, the nitrogen pump is turned on, and the cleaning liquid on the outer wall of the sample needle is removed through the umbrella-shaped air outlet 2003-1;

[0058] S9. Finally, the sample needle is reset through the driving unit 21, and the turntable 45 is rotated to the next sample bottle 452 through the rotating motor 42. Then, the sample needle repeats steps S4 to S8 to complete the injection, cleaning and drying actions.

[0059] The above description is only the preferred implementation of the utility model, and is not intended to limit the utility model. For those skilled in the art, the utility model can have various modifications and changes. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included in the protection scope of the utility model.

Claims

1. A liquid level detection device for a liquid chromatography mobile phase, characterized in that: include, Mounting seat (1); A cleaning unit (2) is arranged on the mounting seat (1) and is used for cleaning the outer wall of the sample needle; the cleaning unit (2) comprises a mounting base plate (20), the bottom of the mounting base plate (20) being fixedly provided with a cleaning groove (200); the bottom of the cleaning groove (200) is provided with a waste liquid discharge port (2001), the top surface of the cleaning groove (200) is formed with a first notch (202) and a second notch (2003), and both sides of the cleaning groove (200) and away from the first notch (202) and the second notch (2003) are provided with an air inlet interface (2004) and a second notch (2005). A liquid inlet interface (2006), a cleaning liquid annular cavity (202-0) and a nitrogen annular cavity (2003-0) are respectively formed inside the first notch (202) and the second notch (2003), a plurality of umbrella-shaped liquid outlets (202-1) and umbrella-shaped gas outlets (2003-1) are respectively formed on the inner walls of the first notch (202) and the second notch (2003), and a rinsing cavity (2007) and a drying cavity (2008) are respectively formed inside the cleaning tank (200); The driving unit (21) is arranged on the mounting seat (1) and is used to realize the up-down and forward-backward movement of the sample needle and automatic sampling.

2. A liquid level detection device for liquid chromatography mobile phase according to claim 1, characterized in that: The plurality of umbrella-shaped liquid outlets (202-1) and the plurality of umbrella-shaped air outlets (2003-1) all have an inclination R, wherein R is greater than or equal to 20 degrees or less than or equal to 135 degrees.

3. A liquid level detection device for liquid chromatography mobile phase according to claim 1, characterized in that: The driving unit (21) comprises a guide rail bracket, a sliding seat (210) is slidably arranged on the guide rail bracket, and a driving motor (211) for driving the sample needle to move forward and backward is fixedly arranged at one end of the guide rail bracket, and the driving motor (211) is matched with a guide member (214) for the sample needle to move forward and backward; a lifting motor (217) is arranged on one side of the sliding seat (210), and one end of the lifting motor (217) is connected to a connecting seat connected to the sliding seat (210), so that the lifting motor (217) can move forward and backward through the sliding seat (210). The connecting seat drives the sliding seat (210) to move up and down, and the top surface of the sliding seat (210) is provided with a lifting guide (212) for limiting the lifting height of the connecting seat. A liquid level detection sensor (213) is provided on the top surface of the connecting seat at a position away from the sliding seat (210). A fixing kit (216) is fixedly provided at one end of the connecting seat, and the fixing kit (216) is used to fix the sample needle. A forward and backward movement position sensor (215) is provided on one side surface of the connecting seat and away from the liquid level detection sensor (213).

4. A liquid level detection device for liquid chromatography mobile phase according to claim 1, characterized in that: A rotating unit (4) is arranged on the mounting seat (1), wherein the rotating unit (4) comprises a rotating disk (45) arranged on the top surface of the mounting seat (1), and the rotating disk (45) is used to place a sample injection bottle.

5. A liquid level detection device for liquid chromatography mobile phase according to claim 4, characterized in that: A second fixing seat (41) is fixedly provided at the bottom of the mounting seat (1) and is used to fix a rotating motor (42), and the rotating motor (42) cooperates with a driven wheel (43) to drive the turntable (45) to rotate, and a motor tensioning seat (44) is also provided between the rotating motor (42) and the driven wheel (43), a waste liquid tank (47) is fixedly provided at the bottom of the mounting seat (1) and close to the driven wheel (43), and a sensor (46) for detecting the position of the turntable (45) is provided on one side of the top of the mounting seat (1).

6. A liquid level detection device for liquid chromatography mobile phase according to claim 5, characterized in that: The top surface of the turntable (45) is formed with a plurality of sample bottle positions (452) for placing bottles, and washing reagent bottle positions (450) and drain positions (451) are arranged at the head and tail ends of the plurality of sample bottle positions (452); the bottom of the drain position (451) is hollow.

7. A liquid level detection device for liquid chromatography mobile phase according to claim 1, characterized in that: An injection unit (3) is arranged on the mounting seat (1); the injection unit (3) includes an injection box (30), a mounting bracket (31) arranged on the injection box (30), the front end surface of the injection box (30) is connected to an injection pump (32), a first fixed seat (33) is arranged on the mounting bracket (31), a sample needle bottom position sensor (34) and a sample needle top position sensor (35) are arranged on one side of the first fixed seat (33), and the sample needle bottom position sensor (34) is located above the sample needle top position sensor (35).

8. A liquid level detection device for liquid chromatography mobile phase according to claim 1, characterized in that: A washing box (5) is arranged on the mounting seat (1) and close to the cleaning unit (2), and a switching valve module (6) is arranged on the front end surface of the washing box (5).

Images